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Outline SLUDGE * S-Salivation * L-Lacrimation * U-Urination * D-Defecation * G-Gastric upset * E-Emesis

Description A cholinergic crisis can occur if the body stops properly breaking down Acetylcholine. This can cause overactivity of Acetylcholine at the neuromuscular junction. Acetylcholine is part of Rest & Digest (Parasympathetic) – so we see overactive digestion and secretion.