COVID-19 Blog ## Update Monday, May 25, 2020
aerosols as well as droplets, so maybe distancing of less value in closed rooms and in the line of air flow from infected to uninfected
Aerosols with long persistence in the air and carriage on air currents
Droplets in sputum or talking that drop away pretty quickly
Fomites and surface transmission probably not so high * Up to 3 days asymptomatic but contagious
Face masks useful only when case numbers are high,
Testing is problematic as still there is no “gold standard”, the PCR testing and antibody testing measure different things and should NOT be conflated
PCR measures viral RNA that belongs to SARS-CoV-2 but which may not be infectious virus. Sometimes it settles after 14 days and sometimes it appears that infected individuals can carry actual viral particles for over 40 days
Antibody testing is measurement of the immune response to the SARS-CoV-2 developed during a COVID-19 infection. We do not know if it is protective, nor for how long it is protective. It’s the part of the immune response that any vaccine is likely to target.
Persistent fatigue after COVID-19 - ?awakening of old EBV, coinfection
I think the issue of coinfection and the consequences of reactivated old battles of our immune systems against herpesviruses and maybe mycoplasma, chlamydia and the like may be an issue
Predispositions to persistent viral symptoms may depend on innate immune redispositions such as mannose-binding lectin deficiency or being a Lewis non-secretor. These allow for pathogen persistence or adhesion that may end up being important inherited risks for complications
Natural therapies with evidence = Vit D and Vit A, probably zinc and ascorbate at mod doses * Olfactory loss - treatment with omega-3 fish oils and vit A nasal spray
Clotting issues apparent now, maintaining omega-3, salicylates in diet and maybe even low dose asirin
Up immunity to prevent and in early stages of the illness, then dampen down and settle so that 2nd phase does not get out of hand