DTB podcast: Recent Episodes

BMJ Group

For 50 years, Drug and Therapeutics Bulletin (DTB) has provided rigorous and independent evaluations of, and practical advice on, individual treatments and the overall management of disease for doctors, pharmacists and other healthcare professionals. DTB has always been wholly independent of the pharmaceutical industry, Government and regulatory authorities. DTB is also free of advertising and other forms of commercial sponsorship. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page - https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. * The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

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In this podcast accompanying the March 2026 issue of the DTB (https://dtb.bmj.com/content/64/3), Syba Sunny (DTB Clinical Editor) is joined by Shivali Fulchand (Editorials and Education editor at The BMJ). Syba and Shivali discuss this month’s editorial on clinically important differences (https://dtb.bmj.com/content/64/3/34) and talk about why this is such an important topic. Then they go on to talk through the DTB’s drug review on the new adrenaline nasal spray that’s been formulated for the treatment of anaphylaxis (https://dtb.bmj.com/content/64/3/36). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us, please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the February 2026 issue of the DTB (https://dtb.bmj.com/content/64/2), Syba Sunny (DTB Clinical Editor) is joined by Julian Treadwell (DTB Associate Editor). Syba and Julian start by talking about this month’s ‘thank you’ editorial (https://dtb.bmj.com/content/64/2/18) before delving into the hot topic of GLP-1 drugs for the treatment of obesity, which is the subject of a DTB review article that summarises what is known about their benefits and harms (https://dtb.bmj.com/content/64/2/19). Finally, they discuss an intervention to reduce sedative use in patients who have been taking these drugs for a long time (https://dtb.bmj.com/content/64/2/25).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us, please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the January 2026 issue of the DTB (https://dtb.bmj.com/content/64/1), Syba Sunny (DTB Clinical Editor) is joined by Tom Nolan, an NHS general practitioner and Clinical Editor at BMJ Medicine. Syba and Tom first talk through this month’s editorial on disinformation and misinformation (https://dtb.bmj.com/content/64/1/2), and discuss ways to combat these in medicine. They then provide an overview of a DTB Forum article, which explains the benefits of taking people off antidepressants using the hyperbolic tapering method (https://dtb.bmj.com/content/64/1/3). The episode ends with Tom sharing his thoughts about the role of artificial intelligence (AI) in primary care.

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us, please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the December issue of the DTB (https://dtb.bmj.com/content/63/12), David Phizackerley (DTB Editor) is joined by Syba Sunny (Clinical Editor). David and Syba discuss this month’s editorial, written by Julian Treadwell, academic GP and DTB editorial board member, which delves into the challenges of prioritising preventative medicine in primary care (https://dtb.bmj.com/content/63/12/178). They then talk about a review article that provides an overview of the new drug elinzanetant, a non-hormonal treatment for vasomotor symptoms associated with menopause (https://dtb.bmj.com/content/63/12/182). Finally, the journal bids an emotional farewell to David, who is retiring after many good years at the DTB.
Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us, please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the November issue of DTB (https://dtb.bmj.com/content/63/11) David Phizackerley (DTB Editor) is joined by Syba Sunny (DTB Clinical Editor). David and Syba discuss the editorial that argues that NHS budgets should not be used to ensure that pharmaceutical companies invest in the UK (https://dtb.bmj.com/content/63/11/162). They talk about a DTB Select article that summarises a systematic review and meta-analysis of trials that assessed patients with a reported penicillin or beta-lactam allergy who underwent direct oral penicillin challenge (https://dtb.bmj.com/content/63/11/163). They finish by discussing the main article that explores the intersection of medication errors, prescribing errors, harms resulting from the use of medicines and some legal consequences (https://dtb.bmj.com/content/63/11/168).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the October issue of DTB (https://dtb.bmj.com/content/63/10) David Phizackerley (DTB Editor) is joined by Julian Treadwell (DTB Associate Editor). David and Julian discuss the editorial that highlights a few of the challenges associated with the introduction of an orphan medicine into clinical practice (https://dtb.bmj.com/content/63/10/146). They talk about a DTB Select article that summarises a randomised clinical trial that assessed the effect of allopurinol on cardiovascular outcomes in people with ischaemic heart disease who did not have gout (https://dtb.bmj.com/content/63/10/147). They finish by discussing the main article that provides an overview of the evidence for mavacamten (▼Camzyos) for the treatment of symptomatic obstructive hypertrophic cardiomyopathy in adults (https://dtb.bmj.com/content/63/10/150). LinksGP Evidence: https://gpevidence.org/Preventing Overdiagnosis 2025 International Conference: https://www.cebm.ox.ac.uk/preventing-overdiagnosis Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the September issue of DTB (https://dtb.bmj.com/content/63/9), David Phizackerley (DTB Editor) is joined by Syba Sunny (DTB Clinical Editor). David and Syba discuss the editorial that highlights changes to antibiotic susceptibility reports, and in particular, the change to the 'I' classification from 'intermediate' to 'susceptible, increased exposure’ (https://dtb.bmj.com/content/63/9/130). They talk about a DTB Select article that summarises an evidence review of deprescribing interventions in primary care and the importance of collaborative multidisciplinary teams, education and training, and shared-decision making (https://dtb.bmj.com/content/63/9/131). They finish by discussing the main article that provides an overview of pharmacological management of chronic heart failure with reduced ejection fraction and the four main groups of drugs that form the four pillars of treatment (https://dtb.bmj.com/content/63/9/133). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the August issue of DTB (https://dtb.bmj.com/content/63/8), David Phizackerley (DTB Editor) is joined by James Cave (former DTB Editor-in-Chief). David and James discuss an editorial generated by artificial intelligence (AI) (https://dtb.bmj.com/content/63/8/114) which looks at the role of AI in publishing. They talk about a DTB Forum article (https://dtb.bmj.com/content/63/8/115) that explores some of the practical problems of implementing drug safety alerts. A DTB Select article (https://dtb.bmj.com/content/63/8/117) provides an overview of a double-blind, randomised, placebo-controlled trial of tirzepatide for weight reduction in people without diabetes. They finish by reviewing the main article (https://dtb.bmj.com/content/63/8/118) that provides an overview of the evidence for lecanemab for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease. Link
BMJ policy on AI use: https://www.bmj.com/content/ai-use Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the July issue of DTB (https://dtb.bmj.com/content/63/7), David Phizackerley (DTB Editor) is joined by Syba Sunny (Clinical Editor). David and Syba discuss the editorial (https://dtb.bmj.com/content/63/7/98) which focuses on some key changes in the new national asthma guideline and the implications for patients and healthcare professionals. A DTB Select article (https://dtb.bmj.com/content/63/7/99) provides an overview of a double-blind randomised placebo-controlled trial that assessed whether bisoprolol reduced the number of exacerbations in people with COPD. The main article (https://dtb.bmj.com/content/63/7/103) is an overview of abaloparatide, which is licensed for the treatment of osteoporosis in postmenopausal women at increased risk of fracture. The podcast begins with a discussion about ideas for new articles for DTB and the therapeutic areas currently under consideration. If you have a suggestion for an article that you would like DTB to cover, please email details to dtb@bmj.com. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the June issue of DTB, David Phizackerley (DTB Editor) is joined by Julian Treadwell (DTB Associate Editor) and Laurence Leaver (GP). David and Julian start by discussing the editorial - https://dtb.bmj.com/content/63/6/82 - which highlights some of the challenges in preventing VTE in early pregnancy. They also talk about a cohort study - https://dtb.bmj.com/content/63/6/84 - that assessed whether gabapentinoid use was associated with severe exacerbations among patients aged >55 years with chronic obstructive pulmonary disease (COPD). In the second half of the podcast, Julian talks to Laurence about two articles - https://dtb.bmj.com/content/63/5/74 and https://dtb.bmj.com/content/63/6/85 - he wrote on managing ADHD in adults. Their discussion includes issues relating to diagnosis, effectiveness of medication, starting and titrating medication and some of the common adverse effects associated with medication. Both articles are currently free to access on the DTB website. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast accompanying the May issue (https://dtb.bmj.com/content/63/5) of DTB, David Phizackerley (DTB Editor) welcomes Syba Sunny (DTB Clinical Editor) to the podcast. Syba provides an overview of her role with DTB, discusses her previous work as a Consultant Microbiologist and talks about areas of interest for future DTB articles. The editorial (https://dtb.bmj.com/content/63/5/66) discusses a paper in The BMJ which proposed offering a polypill containing rosuvastatin, hydrochlorothiazide, amlodipine and losartan to all people in the UK over the age of 50 years to reduce the risk of heart attacks and strokes.

A DTB Select item (https://dtb.bmj.com/content/63/5/68) summarises the results of a small study that assessed whether cytisinicline (cytisine) plus behavioural support was more effective than behavioural support alone for vaping cessation. The main article (https://dtb.bmj.com/content/63/5/74) is the first of two articles on the medical management of ADHD and there will be a longer discussion and an interview with the author in the June podcast.

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early March, David Phizackerley (DTB Editor-in-Chief) and James Cave (DTB Editor-in-Chief Emeritus) provide an overview of the April 2025 issue of DTB. The editorial discusses concerns over the use of feminist empowerment messages to sell tests and treatments - https://dtb.bmj.com/content/63/4/50. A DTB Select item summarises the results of an observational study that assessed the association between initiation of a triptan and the risk of myocardial infarction or stroke - https://dtb.bmj.com/content/63/4/51. The main article provides an overview of initiating angiotensin-converting enzyme inhibitors or angiotensin-II receptor antagonists in adults with CKD, highlighting current guideline recommendations and providing a practical approach to dealing with the challenges associated with their use - https://dtb.bmj.com/content/63/4/54. Links
Health Innovation Network: https://thehealthinnovationnetwork.co.uk/news/launch-of-new-game-changing-guide-to-tackle-overprescribing-and-support-governments-shifts-to-prevention-and-community/ Tackling overprescribing report: https://thehealthinnovationnetwork.co.uk//wp-content/uploads/2025/02/Health-Innovation-Network-Polypharmacy-Guide-Feb-2025.pdf GP Evidence: (https://gpevidence.org/) Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early February, David Phizackerley and Julian Treadwell (DTB Associate Editor) provide an overview of the March 2025 issue of DTB. Julian talks about his work as an academic GP based at Bristol University. He explains why and how he developed the GP Evidence website (https://gpevidence.org/) as a resource for health professionals to use as part of a shared decision making process, and talks about the importance of providing patients with information on the absolute benefits and harms of different treatment options for long-term conditions. The editorial discusses a paper published in The Lancet on the population-health impact of new drugs recommended by NICE and highlights the tension between NICE's role in ensuring that treatments are a cost-effective use of taxpayers’ money and its role in championing the for-profit life-sciences - https://dtb.bmj.com/content/63/3/34. A DTB Select item summarises safety alerts issued by the US Food and Drug Administration and the European Medicines Agency on liver problems associated with fezolinetant (▼Veoza), a drug licensed for the treatment of moderate-to-severevasomotor symptoms associated with the menopause - https://dtb.bmj.com/content/63/3/36. The main article provides an overview of systemic anticancer treatments and conventional cytotoxic drugs - https://dtb.bmj.com/content/63/3/37. LinksGP Evidence (https://gpevidence.org/) Naci H, Murphy P, Woods B, et al. Population-health impact of new drugs recommended by the National Institute for Health and Care Excellence in England during 2000–20: a retrospective analysis. The Lancet 2025;405:50–60. (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02352-3/fulltext)
Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early January, David Phizackerley provides a brief overview of the February 2025 issue of DTB. The editorial discusses the importance of shared decision making and calls on guideline developers to produce patient decision aids to accompany their guidance - https://dtb.bmj.com/content/63/2/18. A DTB Select item summarises a study that evaluated implementation of NHS England’s type 2diabetes path to remission programme - https://dtb.bmj.com/content/63/2/19. The authors of a DTB Commentary article review a UK primary care study which reported that treatment with antihypertensive medicines in older people with complex health needs was associated with an increased risk ofacute kidney injury (AKI) and a short-term increased risk of falls - https://dtb.bmj.com/content/63/2/20. The main article explores the evidence for gefapixant in the treatment of refractory or unexplained chronic cough in adults - https://dtb.bmj.com/content/63/2/22. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early December, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the January 2025 issue of DTB. They provide an overview of the editorial that questions whether it is time for the medicine Patient Information Leaflet (PIL) to include information on the impact of a medicine on clinical outcomes - https://dtb.bmj.com/content/63/1/2. They talk about a recent announcement from the Irish College of GPs that it is phasing out sponsorship from pharmaceutical companies as evidence suggests that ‘engagement between pharmaceutical companies and prescribers is associated with inappropriately increased prescribing rates, lower prescribing quality and increased prescription costs’ - https://dtb.bmj.com/content/63/1/3. The main article provides an overview of Ryeqo (relugolix, estradiol and norethisterone acetate) for the treatment of moderate to severe symptoms of uterine fibroids - https://dtb.bmj.com/content/63/1/6. The podcast ends with a farewell to James, who is stepping down as Editor-in-Chief after more than 12 years. James reflects on his time as a doctor, GP and Editor of DTB. Other links:Is ASCOT all it's cracked up to be? https://www.bmj.com/content/331/7523/1023.1Don't lose your head over ASCOT https://www.bmj.com/content/331/7523/1022.1

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In this podcast recorded in early November, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the December issue of DTB. They provide an overview of the editorial that discusses the need to record the sex and gender of all participants in clinical trials and the importance of recognising diversity and inclusivity in clinical research - https://dtb.bmj.com/content/62/12/178. They talk about a commentary article that addresses claims made in a systematic review that menopausal HT may support neurological function and reduce the risk of Alzeheimer's disease - https://dtb.bmj.com/content/62/12/179. The main article provides an overview of daridorexant for the management of chronic sleep - https://dtb.bmj.com/content/62/12/183.They begin by providing an update on the NICE guidance for tirzepatide and highlighting the publication of a toolkit for repeat prescribing in general practice. Other related linksNICE guidance on tirzepatide: https://www.nice.org.uk/guidance/gid-ta11156/documents/html-content-10Repeat prescribing toolkit: https://www.rpharms.com/resources/repeat-prescribing-toolkit

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In this podcast recorded in early October, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the November issue of DTB. They provide an overview of the editorial that discusses the need to support people taking drugs to help with weight loss: "Providing the drug is only one part of the process and if the other elements are not available to support people with obesity the full benefits of these expensive treatments will not be realised" - https://dtb.bmj.com/content/62/11/162. They talk about the results of an observational study that assessed the risk of major bleeds with concomitant use of selective serotonin reuptake inhibitors (SSRIs) and oral anticoagulants - https://dtb.bmj.com/content/62/11/164. The main article discusses equity of care in the management of COPD and that those more at risk of COPD are also more likely toexperience barriers to care - https://dtb.bmj.com/content/62/11/165. They begin by highlighting two articles in the BMJ that consider the problem of conflicts of interest. Fabbri A, Grundy Q. Protecting early career physicians from commercial influence. BMJ. 2024 Sep 9;386:q1939.(https://www.bmj.com/content/386/bmj.q1939)McCartney M. Transparency as a means to conquer conflicts of interest is illusory. BMJ. 2024 Sep 24;386:q2092.(https://www.bmj.com/content/386/bmj.q2092) Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early September, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the October issue of DTB. They discuss the editorial that highlights the work of the Common Sense in Oncology movement and its aim "to counteract the trend towards irrational, industry-designed, profit-driven cancer drug development" - https://dtb.bmj.com/content/62/10/146. They talk about the results of a systematic review and meta-analysis of two randomised controlled trials that assessed the effect of treating people who have device-detected subclinical atrial fibrillation (AF) with a direct oral anticoagulant - https://dtb.bmj.com/content/62/10/147. The main article discusses the management of hypertension in older people - https://dtb.bmj.com/content/62/10/149. They begin by highlighting an article* that considers the challenges associated with the introduction of new drugs for the treatment of Alzheimer's disease.

*Walsh S, Merrick R, Milne R, et al. Considering challenges for the new Alzheimer's drugs: clinical, population, and health system perspectives. Alzheimers Dement. 2024. doi: 10.1002/alz.14108. [Epub ahead of print 4 Aug 2024].
https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.14108

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early August, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the September issue of DTB. They discuss the editorial (https://dtb.bmj.com/content/62/9/130) that highlights some of the challenges associated with NHS England's national medicines optimisation measures for Integrated Care Boards. They talk about the MHRA's recent safety alert on the risk of an interaction between tramadol and warfarin (https://dtb.bmj.com/content/62/9/131), which was prompted by a coroner's prevention of future deaths report (summarised in a DTB article in March https://dtb.bmj.com/content/62/3/36). The main article reviews the evidence for icosapent ethyl for cardiovascular risk reduction (https://dtb.bmj.com/content/62/9/135).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early July, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) continue to ignore political and sporting events and talk about the August issue of DTB. They discuss the editorial that highlights the growth in the use of psychotropic medication in children and young people and some of the challenges associated with this trend. They talk about a study that assessed the harms of changing frail older people with AF from warfarin to a DOAC. The main article is an overview of the evidence for fezolinetant for the treatment of menopausal vasomotor symptoms.

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early June, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) ignore the UK general election, the T20 cricket world cup and the European football championship and talk about the July 2024 issue of DTB. They discuss the editorial that highlights trial data showing that dupilumab had a modest effect on reducing COPD exacerbations, and question whether more drugs or greater investment in pulmonary rehabilitation and smoking cessation services are a better use of resources. They review a coroner's prevention of future deaths report that highlights the need to raise awareness of the dangers of propranolol overdose. The main article discusses the management of exacerbations of COPD in primary care. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page. If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early May, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the June 2024 issue of DTB. They discuss the editorial that highlights changes to the use of gonadal and fetal shielding for diagnostic imaging (see link). They review the results of a study that assessed the benefit of antibiotics for treating acute sinusitis in children aged 2-11 years. The main article considers the evidence for ritlecitinib, a Janus kinase enzyme inhibitor that is licensed for the treatment of severe alopecia areata in adults and adolescents aged ≥12 years. They begin the podcast by discussing newspaper headlines generated by an international conference on obesity.Linkhttps://www.bir.org.uk/education-and-events/patient-shielding-guidance.aspx

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early April, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the May 2024 issue of DTB. They discuss the editorial that highlights the effect medicines have on greenhouse gas emissions and the need to consider the environmental impact of all aspects of the patient care pathway​ (https://dtb.bmj.com/content/62/5/66). They review the results of a study that assessed the effect of donanemab on early symptomatic Alzheimer's disease​ (https://dtb.bmj.com/content/62/5/67). The main article considers the evidence for cytisine, a nicotine receptor partial agonist, that has recently been licensed to facilitate quitting smoking​ (https://dtb.bmj.com/content/62/5/71). They begin by highlighting some useful resources relating to the safe use of valproate. Other links:https://www.england.nhs.uk/patient-safety/sodium-valproate/ https://www.england.nhs.uk/publication/decision-support-tool-is-valproate-the-right-epilepsy-treatment-for-me/https://www.gov.uk/government/collections/valproate-safety-measureshttps://www.gov.uk/guidance/valproate-use-by-women-and-girls Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early March, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the April 2024 issue of DTB. They discuss the editorial that questions whether drug safety alerts are effective in changing practice and whether more needs to be done to implement safety recommendations (https://dtb.bmj.com/content/62/4/50). They review the Medicines and Healthcare products Regulatory Agency's latest risk minimisation measures for using valproate, which include a guide for healthcare professionals, a guide for patients, an annual risk acknowledgement form and an information card for patients (https://dtb.bmj.com/content/62/4/53). The main article considers the evidence for a new progestogen only pill containing drospirenone (https://dtb.bmj.com/content/62/4/55). They begin by discussing recent concerns over neuropsychiatric reactions associated with montelukast.

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early February, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the March 2024 issue of DTB. They discuss the editorial highlighting the important work that the founders of The Medical Letter, Worst Pills, Best Pills and Drug and Therapeutics Bulletin did to scrutinise the safety of medicines and the need to challenge the processes by which medicines are licensed, appraised, commissioned and promoted (https://dtb.bmj.com/content/62/3/34). They review a coroner's Prevention of Future Deaths report that highlighted an interaction between tramadol and warfarin (https://dtb.bmj.com/content/62/3/36). They also talk about a study that compared the emergency contraceptive efficacy of levonorgestrel plus piroxicam with levonorgestrel plus placebo (https://dtb.bmj.com/content/62/3/38). The main article considers the effectiveness of low or very low calorie diets in achieving remission of type 2 diabetes (https://dtb.bmj.com/content/62/3/39). LinkMathew R. Prescribing isn’t a single act—getting it right requires time and effort. BMJ 2024;384:q279 (https://www.bmj.com/content/384/bmj.q279)

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in early January, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the February 2024 issue of DTB. They discuss the editorial that highlights problems associated with shortages of ADHD medicines. They talk about two safety alerts issued by the Medicines and Healthcare products Regulatory Agency that focus on the adverse effects of fluoroquinolone antibiotics on physical and mental health. The main article considers various NHS initiatives that have attempted to limit primary care prescribing of drugs that are deemed to have limited clinical value. They begin the podcast with sad news of the death of Dr Sidney Wolfe (1937-2024), a colleague and friend who co-founded the US Health Research Group and Public Citizen (a nonprofit consumer advocacy organisation) and who was "a towering public health leader and an unparalleled consumer champion". Links* Remembering Sid Wolfe: https://www.citizen.org/remembering-sidney-wolfe/ * Mandatory disclosure of all pharmaceutical and medical device companies’ payments to healthcare providers: learning from the US: https://dtb.bmj.com/content/60/4/52 * Worst Pills, Best Pills: https://www.citizen.org/topic/safe-affordable-drugs-devices/worst-pills-best-pills/

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast recorded in BMA House in December, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the January 2024 issue of DTB. They discuss continuity of care in general practice and the benefits it offers (https://dtb.bmj.com/content/62/1/2). They discuss a safety alert issued by the Medicines and Healthcare products Regulatory Agency that highlights a very small number of reports of new-onset or aggravation of pre-existing myasthenia gravis associated with statins (https://dtb.bmj.com/content/62/1/4). The main article is an overview of the management of acne (https://dtb.bmj.com/content/62/1/6). They begin the podcast by providing a brief update on the results of a trial that assessed the effect of semaglutide on cardiovascular outcomes in people aged ≥45 years with cardiovascular disease (but not diabetes) and a BMI ≥27 kg/m2 (plot spoiler: make sure you know your ARRs from your RRRs).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the December 2023 issue of DTB. They discuss monitoring drugs in primary care and the need to rationalise the number of blood tests undertaken (https://dtb.bmj.com/content/61/12/178). They talk about a study that reported the effect of bempedoic acid on a composite cardiovascular outcome (https://dtb.bmj.com/content/61/12/180). The main article is a review of semaglutide as an option for weight management and discusses the evidence for its use and some of the hype that has surrounded the its launch (https://dtb.bmj.com/content/61/12/182). They begin by responding to a listener's complaint about terminology. Related link: Aronson JK. When I use a word . . . Medicines regulation—apothecaries, quacks, chemists, druggists, pharmacists. BMJ 2023;383:p2603. https://www.bmj.com/content/383/bmj.p2603 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the November 2023 issue of DTB. They discuss the history of the BNF and the announcement that the 86th edition of the BNF and the 2023–2024 edition of the BNF for Children will be the last print issues to be purchased by the National Institute for Health and Care Excellence for the NHS in England (https://dtb.bmj.com/content/61/11/162 and https://dtb.bmj.com/content/61/11/166). They talk about a retrospective review of a case series of UK coroners’ Reports to Prevent Future Deaths that found that around one in five reports involved a medicine (https://dtb.bmj.com/content/61/11/165). The main article provides an introduction to pharmacogenetics (https://dtb.bmj.com/content/61/11/168). They begin by responding to a listener's email. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the October 2023 issue of DTB. They discuss NHS prescription charges in England and the impact they have on people with long-term ill health (https://dtb.bmj.com/content/61/10/146). They talk about a study that assessed the incidence of retinopathy associated with hydroxychloroquine (https://dtb.bmj.com/content/61/10/148). The main article discusses intravenous vitamins and reviews the evidence for their use for serious medical conditions and the evidence for their use in the absence of a specific vitamin deficiency or medical condition (https://dtb.bmj.com/content/61/10/151). The latest issue of Australian Prescriber mentioned in thia podcast is available from https://australianprescriber.tg.org.au/. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the September 2023 issue of DTB. They discuss concerns over redacted data in NICE appraisal documents (https://dtb.bmj.com/content/61/9/130). They review a placebo-controlled study that assessed the use of spironolactone for women with acne (https://dtb.bmj.com/content/61/9/132). The main article explores anticholinergic burden and the risk of cognitive decline, dementia and increased mortality associated with long-term use of drugs with anticholinergic activity (https://dtb.bmj.com/content/61/9/135).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the August 2023 issue of DTB. They discuss measurement of fractional exhaled nitric oxide (FeNO) in the management of asthma (https://dtb.bmj.com/content/61/8/114). They review a study that assessed the use of H. pylori eradication in people taking low-dose aspirin (https://dtb.bmj.com/content/61/8/116). The main article explores the evidence for the use of finerenone for CKD associated with type 2 diabetes (https://dtb.bmj.com/content/61/8/120).

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the July 2023 issue of DTB. They discuss evidence-based medicine, access to evidence and increasing use of press releases and social media to present evidence (https://dtb.bmj.com/content/61/7/98). They talk about the safety of isotretinoin (https://dtb.bmj.com/content/61/7/99) and review a study that assessed the accuracy of conflict of interest statements in clinical guidelines (https://dtb.bmj.com/content/61/7/100). The main review article explores the evidence for cardiac and renal effects of SGLT2 inhibitors (https://dtb.bmj.com/content/61/7/103). They begin by discussing the impact of the shortage of Utrogestan.

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In a series of podcasts to mark the 60th anniversary of DTB, we talk to some of DTB's Editorial Board members and other colleagues about their work and their involvement with DTB. In this podcast, David Phizackerley (DTB deputy editor) talks to Barbara Mintzes (DTB associate editor) who is Associate Professor at the School of Pharmacy and Charles Perkins Centre at the University of Sydney, where she has worked since 2015. Her background is in epidemiology and the main focus of her work is on pharmaceutical policy, including the effects of direct-to-consumer advertising and physician-directed promotion on medicine use. Barbara talks about her interest in medicines policies, the impact of pharmaceutical and medical device company payments to clinicians, medicalisation of normal life, medicine safety scandals and the impact on those who have been harmed by medicines with a particular focus on women's health. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the June 2023 issue of DTB. They discuss new guidelines on post-exposure prophylaxis
for varicella or shingles during pregnancy (https://dtb.bmj.com/content/61/6/82). They review the effect of low-dose aspirin on fractures and falls (https://dtb.bmj.com/content/61/6/85), and talk about a study that does not provide meaningful cardiovascular outcome data for inclisiran (https://dtb.bmj.com/content/61/6/86). The main review article explores hospitalisation as a consequence of medication-related harm and the need to reduce the burden of harm caused by medication (https://dtb.bmj.com/content/61/6/87). They begin by discussing an announcement from NHS England that antibiotics will be provided without the need for a prescription from community pharmacies to free up GP time.

The contact address for the DTB team is dtb@bmj.com.
Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the June 2023 issue of DTB. They discuss new guidelines on post-exposure prophylaxis for varicella or shingles during pregnancy (https://dtb.bmj.com/content/61/6/82). They review the effect of low-dose aspirin on fractures and falls (https://dtb.bmj.com/content/61/6/85), and talk about a study that does not provide meaningful cardiovascular outcome data for inclisiran (https://dtb.bmj.com/content/61/6/86). The main review article explores hospitalisation as a consequence of medication-related harm and the need to reduce the burden of harm caused by medication (https://dtb.bmj.com/content/61/6/87). They begin by discussing an announcement from NHS England that antibiotics will be provided without the need for a prescription from community pharmacies to free up GP time.

The contact address for the DTB team is dtb@bmj.com. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the May 2023 issue of DTB. They celebrate 60 years since DTB became independent from The Medical Letter and discuss what DTB stands for (https://dtb.bmj.com/content/61/5/66). They review a retrospective cohort study involving people taking oral anticoagulants that compared the risk of bleeding and embolic events in new users of NSAIDs with those not prescribed NSAIDs (https://dtb.bmj.com/content/61/5/67). They also talk about the main review article that explores the therapeutics of siRNA medicines (https://dtb.bmj.com/content/61/5/72). They begin by discussing the UK Government’s recent Budget statement that the MHRA will introduce a new approval process for medicines that have been licensed elsewhere.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the April 2023 issue of DTB. They discuss evidence around morning and evening doses of antihypertensive medication (https://dtb.bmj.com/content/61/4/50). They review a study that analysed health technology assessment decisions made in Australia, Canada and England (https://dtb.bmj.com/content/61/4/51) and also talk about managing skin conditions in women who are planning pregnancy or who are pregnant (https://dtb.bmj.com/content/61/4/55). They begin by responding to a listener's letter about last month's podcast.The Prescribing for pregnancy series of articles can be found here: https://dtb.bmj.com/pages/prescribing-for-pregnancy-series/

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In a series of podcasts to mark the 60th anniversary of DTB, we talk to some of DTB's Editorial Board members and other colleagues about their work and their involvement with DTB. In this podcast, recorded May 2022, David Phizackerley (DTB's deputy editor) talks to Joanna Girling who is a consultant in obstetric medicine in north London and has been involved with DTB since 2006. Joanna talks about her clinical work, her role with establishing the local maternity network and her involvement in research. She also talks about supporting women who have pre-existing medical conditions and who are pregnant or who are planning pregnancy and the importance of checking that they are on the most appropriate medicines.The contact address for the DTB team is dtb@bmj.com.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listenin

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the March 2023 issue of DTB. They discuss incorrect penicillin allergy labels and ways that these can be corrected (https://dtb.bmj.com/content/61/3/34). They review clinical trial results for lecanameb in early Alzheimer's disease (https://dtb.bmj.com/content/61/3/37) and also talk about a new combined oral contraceptive that contains estetrol and drospirenone (https://dtb.bmj.com/content/61/3/39). They begin by discussing a proposal from the National Institute for Health and Care Excellence to lower the threshold for offering statins for primary prevention.The contact address for the DTB team is dtb@bmj.com.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the February 2023 issue of DTB. They discuss concerns over a national initiative in England to transfer people with atrial fibrillation to edoxaban from other DOACs (https://dtb.bmj.com/content/61/2/18). They review a study that examined whether the correct dose of DOAC was used in people with renal impairment (https://dtb.bmj.com/content/61/2/21). They talk about the use of empagliflozin in people with heart failure (https://dtb.bmj.com/content/61/2/22) and finish with an overview of an article that discusses prescribing for pregnancy for those with inflammatory rheumatic disease (https://dtb.bmj.com/content/61/2/24).60th anniversary interview with Dr John Dowden: https://soundcloud.com/bmjpodcasts/dtb-60th-anniversary-podcast-interview-john-dowdenTrends in direct oral anticoagulant (DOAC) prescribing in English primary care (2014–2019): https://heart.bmj.com/content/109/3/195The contact address for the DTB team is dtb@bmj.com.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In a series of podcasts to mark the 60th anniversary of DTB, we talk to some of DTB's Editorial Board members and other colleagues about their work and their involvement with DTB.In this podcast, David Phizackerley (DTB's deputy editor) talks to Dr John Dowden, the editor of Australian Prescriber since 1990. Australian Prescriber (https://www.nps.org.au/australian-prescriber) is an independent peer-reviewed journal providing critical commentary on drugs and therapeutics for health professionals, and like DTB, Australian Prescriber was a founder member of the International Society of Drug Bulletins. At the time of recording, John highlighted that public funding for NPS Medicinewise (https://www.nps.org.au/), the organisation that publishes Australian Prescriber, was under threat and unfortunately the Australian Government withdrew funding and the organisation closed at the end of December. John and his team were made redundant, and the future of Australian Prescriber is uncertain.We wrote an editorial that criticises the decision to remove funding from NPS Medicinewise and you can find this in the January 2023 issue of DTB (https://dtb.bmj.com/content/61/1/2).This special series of the DTB Podcast is produced by Leticia Amorim.This podcast was edited by Brian O'Toole.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the January 2023 issue of DTB. They begin with another reminder of the concerns over the use of sodium valproate. They talk about the closure of NPS MedicineWise in Australia and the uncertainty over the future of Australian Prescriber - https://dtb.bmj.com/content/61/1/2. They highlight the risk of eye problems with dupilumab - https://dtb.bmj.com/content/61/1/6 (see more links below) and the challenge of making sure that primary care clinical systems record drugs prescribed by specialists. They discuss toxocarosis in humans and the risk of environmental contamination from parasiticides used for deworming cats and dogs (https://dtb.bmj.com/content/61/1/3 and https://dtb.bmj.com/content/61/1/7).Dupilumab links:1. Reji MA, Haque A, Goyal S, et al. Dupilumab-induced ocular surface disease: a primer. BMJ Case Reports CP 2022;15:e249019. https://casereports.bmj.com/content/15/4/e2490192. Nahum Y, Mimouni M, Livny E, et al. Dupilumab-induced ocular surface disease (DIOSD) in patients with atopic dermatitis: clinical presentation, risk factors for development and outcomes of treatment with tacrolimus ointment. British Journal of Ophthalmology 2020;104:776-9. https://bjo.bmj.com/content/104/6/776The contact address for the DTB team is dtb@bmj.com.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the December 2022 issue of DTB. They discuss cognitive changes that have been reported during the menopause and whether there is a role for MHT (https://dtb.bmj.com/content/60/12/178). They highlight an observational study that found an association between the use of sodium-containing paracetamol and cardiovascular events (https://dtb.bmj.com/content/60/12/181), and talk about the evidence for increasing the dose of vedolizumab in IBD (https://dtb.bmj.com/content/60/12/183). They begin the podcast by talking about their top three highlights from 2022.The contact address for the DTB team is dtb@bmj.com.Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In a series of podcasts to mark the 60th anniversary of DTB, we talk to some of DTB's Editorial Board members and other colleagues about their work and their involvement with DTB.

In this podcast, David Phizackerley (DTB's deputy editor) talks to Dr Jo Congleton, who is a consultant in Integrated Respiratory Care in Brighton and Hove. She is also clinical lead for the Kent, Surrey, Sussex Academic Health and Science Network (AHSN) Respiratory Programme. Her interests are in chronic respiratory conditions (particularly COPD) and reducing both variation, and inequalities, in care.

This special series of the DTB Podcast is produced by Leticia Amorim.

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the November 2022 issue of DTB. They discuss the use of faecal microbiota transplantation to treat gastrointestinal infections and in particular its role in managing Clostridioides difficile infection (https://dtb.bmj.com/content/60/11/162). They highlight a study that assessed the effect of interrupting methotrexate treatment on COVID-19 booster vaccine response (https://dtb.bmj.com/content/60/11/163) and review a new drug that is licensed for treatment of patients aged 4 to 17 years with a confirmed diagnosis of peanut allergy (https://dtb.bmj.com/content/60/11/166). The podcast begins with the editors talking about the response to October's editorial "Stop advertising". Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the October 2022 issue of DTB. They discuss whether the language used in announcements from organisations such as NHS England, NICE and the MHRA regarding new medicines is appropriate and highlight concerns that some press releases are at risk of promoting POMs to the public (https://dtb.bmj.com/content/60/10/146). They review a study that assessed the effect that regular doses of paracetamol had on blood pressure (https://dtb.bmj.com/content/60/10/147) and talk about an article that discusses the role played over the past 20 years by groups, organisations and individuals that have been critical of the pharmaceutical industry (https://dtb.bmj.com/content/60/10/151). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the September 2022 issue of DTB. They discuss a new national guideline on the management of gout. They highlight a safety update on the risk of vitamin B12 deficiency with metformin and provide an overview of a study that analysed the way countries across Europe report payments made by pharmaceutical companies to healthcare professionals. They end the podcast with a discussion on the evidence for carbetocin in the prevention of postpartum haemorrhage.

The contact address for the DTB team is dtb@bmj.com.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the August 2022 issue of DTB. They discuss progress in reducing use of psychotropic medications in adults and children with a learning disability, autism or both (https://dtb.bmj.com/content/60/8/114). They also provide an overview of a study that assessed the effect of deprescribing antihypertensive medication in older people (https://dtb.bmj.com/content/60/8/118) and talk about a national safety alert relating to amiodarone (https://dtb.bmj.com/content/60/8/116). They end the podcast with a discussion on the evidence for the lipid-lowering drug bempedoic acid and its effect on reducing low-density lipoprotein-cholesterol and the lack of evidence on clinical outcomes (https://dtb.bmj.com/content/60/8/120). The contact address for the DTB team is dtb@bmj.com. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the July 2022 issue of DTB. They discuss the proposed reclassification of estradiol vaginal tablets from Prescription Only Medicine to a Pharmacy medicine (https://dtb.bmj.com/content/60/7/98) and review a study that assessed pharmaceutical industry funding of All Party Parliamentary Groups (https://dtb.bmj.com/content/60/7/100). They talk about the evidence for the lipid-lowering drug inclisiran and its effect on reducing low-density lipoprotein-cholesterol and the lack of evidence on clinical outcomes (https://dtb.bmj.com/content/60/7/102). The editors also highlight a case report of acute lung toxicity caused by nitrofurantoin (https://dtb.bmj.com/content/60/7/108). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the June 2022 issue of DTB. They discuss the impact that the cessation of spirometry services in primary care has had on diagnosing obstructive lung disease (https://dtb.bmj.com/content/60/6/82). They highlight two separate patient safety incident reports from the Healthcare Safety Investigation Branch - confusion over the prescribed dose of oral morphine solution and the harm caused by a standard therapeutic dose of paracetamol in a frail older person (https://dtb.bmj.com/content/60/6/84). The editors also talk about an article on serotonin syndrome (https://dtb.bmj.com/content/60/6/88). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Read the June issue: https://dtb.bmj.com/content/60/6

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the May 2022 issue of DTB. They talk about drug bulletins across the world and the role of the International Society of Drug Bulletins in supporting bulletins and ensuring that they are intellectually and financially independent (https://dtb.bmj.com/content/60/5/66). They review a study that assessed the use of mirtazapine for treating agitation in people with dementia (https://dtb.bmj.com/content/60/5/68). The editors also discuss the evidence behind two new oral antivirals that have been licensed for the treatment of covid-19 (https://dtb.bmj.com/content/60/5/73). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the April 2022 issue of DTB. They talk about DTB's 60th anniversary, the importance of independent scrutiny of new medicines and the need to question how medicines are licensed and used (https://dtb.bmj.com/content/60/4/50). They highlight the benefits of a comprehensive national register of conflicts of interest and discuss a study that compared a quadpill containing low doses of four antihypertensive agents with a standard dose of irbesartan (https://dtb.bmj.com/content/60/4/56). They also review a study that assessed clinicians' awareness of the harms from long-term use of nitrofurantoin (https://dtb.bmj.com/content/60/4/59) and provide an overview of an article on managing hypertension in pregnancy (https://dtb.bmj.com/content/60/4/60). The editors also look back at the very first issue of DTB that was published on 20th April 1962 (https://dtb.bmj.com/content/s1-1/1). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the March 2022 issue of DTB. They talk about paracetamol and its effect on blood pressure and discuss progress on moving to inhalers that have less of an impact on the environment (https://dtb.bmj.com/content/60/3/34). The editors review a study that examined harms from medicines (https://dtb.bmj.com/content/60/3/37) and discuss the use of naldemedine in the management of opioid-induced constipation (https://dtb.bmj.com/content/60/3/39). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the February 2022 issue of DTB. They talk about some of the details from a national report on overprescribing and discuss its implications (https://dtb.bmj.com/content/60/2/18). The editors review a study that highlighted overprescribing of short-acting beta agonists in people with asthma (https://dtb.bmj.com/content/60/2/21). They also discuss an article on prescribing for women of childbearing age who have inflammatory bowel disease and managing medicines during pregnancy (https://dtb.bmj.com/content/60/2/24). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the January 2022 issue of DTB. They discuss the UK Medicines and Healthcare products Regulatory Agency's decision to license the oral antiviral drug molnupiravir (Lagevrio) and the paucity of publicly available clinical trial data - https://dtb.bmj.com/content/60/1/2. The editors talk about a study that highlighted potentially inappropriate prescribing in middle-aged adults - https://dtb.bmj.com/content/60/1/6. They also review an article on some of the challenges facing people when they try to stop taking antidepressants - https://dtb.bmj.com/content/60/1/7. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the December issue of DTB. They discuss a recently published national report on overprescribing of medicines. The editors talk about a study that assessed the accuracy of home blood pressure monitors (https://dtb.bmj.com/content/59/12/179) and highlight a safety alert on topical steroid withdrawal reactions (https://dtb.bmj.com/content/59/12/184). They also review an article on the US Food and Drug Administration's decision to license bremelanotide and flibanserin for 'hypoactive sexual desire disorder’ in women (https://dtb.bmj.com/content/59/12/185). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the November issue of DTB. They discuss a French initiative that identifies a range of drugs that should not be prescribed (https://dtb.bmj.com/content/59/11/162) and talk about the difficulty of assessing whether patients' penicillin allergy records are correct (https://dtb.bmj.com/content/59/11/163). They also review an article on the use of romosozumab for osteoporosis (https://dtb.bmj.com/content/59/11/169). They begin by highlighting DTB's blog for World Evidence-Based Healthcare Day (https://worldebhcday.org/) on the role of independent drug bulletins during an info-demic. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the October issue of DTB. They discuss the impact of making desogestrel contraceptives available for purchase from pharmacies (https://dtb.bmj.com/content/59/10/146) and talk about the role of percutaneous coronary intervention in patients with stable ischaemic heart disease (https://dtb.bmj.com/content/59/10/150). They also review an article about managing migraine in pregnancy (https://dtb.bmj.com/content/59/10/152). They begin by highlighting the decision to remove pregabalin from the Northern Ireland formulary for neuropathic pain. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the September issue of DTB. They discuss the US FDA's controversial decision to license aducanumab for Alzheimer's disease (https://dtb.bmj.com/content/59/9/130) and consider barriers to prescribing shorter courses of antibiotics in primary care (https://dtb.bmj.com/content/59/9/131). The editors also highlight the impact that some medicines have on oral health and dental treatment (https://dtb.bmj.com/content/59/9/135). Before all of that though, the recent NICE's guideline on shared decision making. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the August issue of DTB (https://dtb.bmj.com/content/59/8). The editors talk about the MHRA's decision to reverse the EMA's decision and allow boron-containing chloramphenicol eye drops to be used in children aged below 2 years. They discuss a scheme in England that allows hospital staff to refer patients who would benefit from extra guidance around their medicines regimen for support from a community pharmacy (https://dtb.bmj.com/content/59/8/114). They also highlight the risk from concurrent opioid and benzodiazepine use (https://dtb.bmj.com/content/59/8/116), and talk about home blood pressure monitoring (https://dtb.bmj.com/content/59/8/119). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the July issue of DTB. The editors catch up on developments with proposals for all doctors in the UK to provide financial and non-financial declarations of interest. They discuss the problem of boron in chloramphenicol eye drop products and the impact on treating children aged under 2 years (https://dtb.bmj.com/content/59/7/98). The editors also talk about PPIs for persistent throat symptoms (https://dtb.bmj.com/content/59/7/102), the dose of folic acid for use with methotrexate (https://dtb.bmj.com/content/59/7/103) and a case of a patient who developed severe hypophosphataemia with an oral bisphosphonate (https://dtb.bmj.com/content/59/7/107). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the June issue of DTB. The list of articles mentioned in this podcast: The Editorial “COVID-19 vaccination in pregnancy” - https://dtb.bmj.com/content/59/6/82 DTB select “Stepping down asthma treatment” - https://dtb.bmj.com/content/59/6/85 Review “Prescribing for pregnancy: managing diabetes” - https://dtb.bmj.com/content/59/6/88 Republished case report “Euglycaemic diabetic ketoacidosis in a 43-year-old woman with type 2 diabetes mellitus on SGLT-2 inhibitor (empagliflozin)” - https://dtb.bmj.com/content/59/6/93 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the May issue of DTB. In light of the "First do no harm" report, the editorial discusses the need for a mandatory register of payments made by pharmaceutical and medical device companies to healthcare professionals, healthcare organisations and patient support organisations (https://dtb.bmj.com/content/59/5/66). The editors talk about the BTS guideline on long-term use of macrolides (https://dtb.bmj.com/content/59/5/67). The main article explores the use of CAR T-cell therapy (https://dtb.bmj.com/content/59/5/73) and the case report is of a patient who developed quinidine hypersensitivity (https://dtb.bmj.com/content/59/5/77). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the April issue of DTB. The editorial discusses variability in the management of people with severe asthma (https://dtb.bmj.com/content/59/4/50). The editors talk about a summary of an article on changes in prescribing of statins (https://dtb.bmj.com/content/59/4/53). The main article explores the use of aspirin for pre-eclampsia (https://dtb.bmj.com/content/59/4/56) and the case report is of a patient who developed omeprazole-induced hypomagnesaemia (https://dtb.bmj.com/content/59/4/60). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) review the March issue of DTB (https://dtb.bmj.com/content/59/3). The editorial discusses a national safety alert that highlighted the risk of dependence associated with prolonged use of opioids for non-cancer pain and a proposal that all opioid medicines in the UK carry the warning "can cause addiction" (https://dtb.bmj.com/content/59/3/34). The editors talk about an article on the rationale and science behind bisphosphonate holidays (https://dtb.bmj.com/content/59/3/35). The main article explores the risk of nitrosamine contamination in medicines (https://dtb.bmj.com/content/59/3/39) and the case report is of a patient who developed an unusually impressive atorvastatin-induced elevation of serum alkaline phosphatase (https://dtb.bmj.com/content/59/3/43). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Also, DTB is running a short survey to find out what people think of our content. Please visit https://dtb.bmj.com to find a link to the survey.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) discuss the February issue of DTB. This includes an editorial that highlights the benefits associated with the human papillomavirus (HPV) and herpes zoster vaccination programmes (https://dtb.bmj.com/content/early/2021/01/11/dtb.2020.000048). The editors talk about a cohort study, which found that many older people who had recently been prescribed a calcium-channel blocker for hypertension were subsequently given a loop diuretic. The main article reviews the use of prescribing safety indicators to improve outcomes for patients and the case report is of a patient who developed immune checkpoint inhibitor-mediated large vessel vasculitis. Read the issue on the DTB website: https://dtb.bmj.com/content/59/2 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) discuss the January issue of DTB (https://dtb.bmj.com/content/59/1). This includes an editorial that highlights the urgent need for more information for the public to support the national COVID-19 vaccination programme (https://dtb.bmj.com/content/59/1/2). The editors talk about the importance of knowing how patients use their medicines at home (https://dtb.bmj.com/content/59/1/3)and discuss advice for population vitamin D supplementation in adults in the UK (https://dtb.bmj.com/content/59/1/7). This month's case report involves two patients who developed severe hypothermia, bradycardia and cardiac arrest in association with risperidone (https://dtb.bmj.com/content/59/1/13). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

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In this podcast James Cave (Editor in Chief) and David Phizackerley (Deputy Editor) discuss some of the challenges associated with the national COVID-19 vaccination programme. In particular, they highlight the importance of making information on the vaccines’ safety and efficacy available to help people make an informed decision on vaccination. Read the paper: https://dtb.bmj.com/content/early/2020/11/24/dtb.2020.000071 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) preview the December issue of DTB. This includes an editorial that discusses the results of a study that suggested that people who took antihypertensive medication at bedtime had a lower risk of a cardiovascular event. The editors talk about a threat to the supply of the Priadel brand of lithium carbonate. They also discuss the use of esketamine for treatment-resistant depression. This month's case report involves an unintentional overdose of hyoscine hydrobromide in a young child. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) preview the November issue of DTB. This includes an editorial that focuses on the National Institute of Health and Care Excellence's draft guideline on the management of chronic pain, and in particular, the approach to treating chronic primary pain (https://dtb.bmj.com/content/58/11/162). The editors talk about a new patient-held steroid emergency card that has been introduced to help healthcare staff identify adult patients with adrenal insufficiency (https://dtb.bmj.com/content/58/11/163). They also discuss the diagnosis and treatment of orthostatic hypotension. This month's case report involves a patient who developed medication-related osteonecrosis (MRONJ) of the mandible and maxilla (https://dtb.bmj.com/content/58/11/172). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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A socially distanced podcast with James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) previewing the October issue of DTB. This includes an editorial that discusses the harms caused by medicines and medical devices and highlights concerns over proposals to speed up the UK licensing process for medicines. The editors talk about an article that looks at the influence of pharmaceutical marketing. They also review three new medicines used to prevent migraines. This month's case report involves a patient with rheumatoid arthritis who received latent tuberculosis infection treatment prior to treatment with a biologic agent, and developed shock with resistant hypotension on re-exposure to rifampicin.

Read the full issue: https://dtb.bmj.com/content/58/10

Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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As we continue with our socially distanced DTB podcasts James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the September issue of DTB. This includes an editorial discussing the challenges facing commissioning organisations when changes to clinical practice or market authorisation have a significant impact on how biological therapies can be used. The editors highlight a study that showed a lack of adherence to guidelines on direct oral anticoagulant dosing in people with atrial fibrillation and renal impairment, and review an article that discusses the risk of seizures with antidepressants. This month's case report involves an Infant with status epilepticus secondary to systemic lidocaine toxicity from topical application. Read the full issue: https://dtb.bmj.com/content/58/9 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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Another socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) who provide an overview of the August issue of DTB. This includes an editorial discussing the changes that have taken place in general practices and the new ways of working that have been developed during the coronavirus pandemic (https://dtb.bmj.com/content/58/8/114). The main article reviews the evidence for using vitamin D and calcium in older people who have osteoporosis (https://dtb.bmj.com/content/58/8/122) and the case report highlights the problems faced by a young man who developed a hyperkinetic reaction to dihydrocodeine (https://dtb.bmj.com/content/58/8/126). Read the full issue: https://dtb.bmj.com/content/58/8. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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Another socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor), who provide an overview of the July issue of DTB. This includes an editorial that discusses some of the challenges in supplying low-dose aspirin to pregnant women for prevention of pre-eclampsia, a DTB Forum article by Margaret McCartney on some of the challenges to evidence-based medicine during the coronavirus pandemic and a DTB Select update on the safety of ibuprofen in people with COVID-19. The main article discusses managing antiepileptic drugs before and during pregnancy for women with epilepsy, and this month's case report is of amiodarone-induced diffuse alveolar haemorrhage. Read the full issue: https://dtb.bmj.com/content/58/7 Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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With the coronavirus pandemic restrictions still in place, this socially distanced DTB podcast features James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor), who provide an overview of the June issue of DTB. This includes an editorial that discusses whether clinicians should be deprescribing some medicines during the pandemic, and a summary of the EMA's advice on the use of drugs that affect the renin-angiotensin system in people who have COVID-19. The main article looks at the gastrointestinal risks of NSAIDs and the evidence for gastroprotection, and the issue finishes with a case report of drug reaction with eosinophilia and systemic symptoms syndrome in a patient taking lamotrigine. Please read the full issue: https://dtb.bmj.com/content/58/6. Subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Go well and stay well.

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As the UK continues to be in lockdown because of the coronavirus pandemic, this podcast only features David Phizackerley, DTB's Deputy Editor, who provides a brief overview of the May issue of DTB. This includes an editorial that discusses the challenges facing clinicians in involving children and young people in decisions about their healthcare; a summary of the EMA's advice on the use of ibuprofen in people who have Covid-19; and an article on the development of shared care prescribing guidelines over the last 30 years. The main article looks at the benefits and harms of using potassium permanganate for wound care, and the issue finishes with a case report of hypersensitivity pneumonitis associated with sertraline. Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (podcasts.apple.com/gb/podcast/dtb-…ast/id307773309). Thank you for listening. Go well and stay well.

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In April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss lung volume reduction surgery for patients with emphysema-predominant COPD (https://dtb.bmj.com/content/58/4/50). They highlight the results of a trial of low-dose amitriptyline for chronic low back pain (https://dtb.bmj.com/content/58/4/53), discuss the use of depot triamcinolone injection for hay fever (https://dtb.bmj.com/content/58/4/57), and talk about a case in which dapagliflozin was thought to have caused euglycaemic diabetic ketoacidosis (https://dtb.bmj.com/content/58/4/60). If you enjoy the DTB podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening. Read the full April issue: dtb.bmj.com/content/58/4

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In March's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the decision to extend the license for dapagliflozin 5 mg tablets to include use by people with type 1 diabetes and highlight concerns over the incidence of diabetic ketoacidosis. They review an article on managing asthma before and during pregnancy and talk about a case of partial nephrogenic diabetes insipidus associated with lithium therapy. Read the full March issue: dtb.bmj.com/content/58/3 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

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In February's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the impact of conflicts of interest and highlight the need to establish comprehensive registers of conflicts of interest for healthcare professionals, healthcare providers and patient support groups. They briefly review an article on melatonin for jet lag (a longer version is available here: https://soundcloud.com/bmjpodcasts/melatonin-for-jet-lag?in=bmjpodcasts/sets/dtb-podcast), discuss a review of the management of nocturnal enuresis and highlight a report of a possible case of statin-induced delayed rhabdomyolysis. Read the full February issue: https://dtb.bmj.com/content/58/2 If you enjoy the podcast, please subscribe to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a formulation of melatonin that has been licensed in the UK for the management of jet lag. The editors review the evidence for its effectiveness in reducing symptoms of jet lag and consider whether it should be available from the National Health Service. Read the article here: http://dx.doi.org/10.1136/dtb.2019.000074. Please subscribe to the DTB Podcast to get episodes automatically downloaded to your phone and computer every month. If you enjoy the show, please leave us a review or a comment at podcasts.apple.com/gb/podcast/dtb-…ast/id307773309. Thank you for listening!

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In January's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the burden of overprescribing and discuss how to tackle some of the barriers to deprescribing (https://dtb.bmj.com/content/58/1/2). They also review an article on the place of aspirin for primary prevention of cardiovascular disease (https://dtb.bmj.com/content/58/1/3), highlight an article on prescribing for pregnancy for women with mental health issues (https://dtb.bmj.com/content/58/1/8), and discuss a case report of sitagliptin-induced seronegative rheumatoid arthritis (https://dtb.bmj.com/content/58/1/12). Please subscribe to get episodes automatically downloaded to your phone and computer every month. If you enjoy the podcast, please leave us a review or a comment at https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309. Thank you for listening.

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In December's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the results of a recent study that assessed the effect of a combination pill containing aspirin, atorvastatin, enalapril and hydrochlorothiazide on major cardiovascular outcomes - https://dtb.bmj.com/content/57/12/178. The editors discuss prasterone, a newly introduced treatment for vulvar and vaginal atrophy - https://dtb.bmj.com/content/57/12/185. They also review a case report of retrograde ejaculation associated with quetiapine and treatment with low-dose imipramine - https://dtb.bmj.com/content/57/12/189. Read the December issue on the DTB website: https://dtb.bmj.com/content/57/12.

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In November's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether primary care targets for managing blood pressure control in older people are achievable or desirable. The editors also introduce the first of a series of articles that consider therapeutic challenges when preparing for pregnancy and highlight some of the key issues that should be considered for all women as part of pre-pregnancy care. They also review a case report of apixaban-induced acute interstitial nephritis. Read the full November issue: https://dtb.bmj.com/content/57/11

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In October's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss wide variation in the use of fibrates and the need for clinicians to consider whether their prescribing of fibrates is up to date and appropriate for their patients. The editors also talk about the evidence for fibrates in primary and secondary prevention of cardiovascular disease, highlight recent changes in the BNF and review a case of severe acute ocular hypertension following pulsed methylprednisolone. Read the full October issue: https://dtb.bmj.com/content/57/10

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In September's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the roll out of social prescribing across the NHS in England. The editors also talk about a new formulation of naloxone for emergency treatment of opioid overdose in adults and review a case that involved successful thrombolysis for acute ischaemic stroke after using idarucizumab to reverse the action of dabigatran etexilate. To read any of the September articles, please visit: https://dtb.bmj.com/content/57/9.

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In August's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss pre-eclampsia and the benefit of measuring the level of placental growth factor to help speed up diagnosis. The editors also talk about the challenge of communicating evidence to patients and review a case of complex encephalopathy arising from the combination of opioids and gabapentin. Read the full issue: https://dtb.bmj.com/content/57/8.

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In July's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the work that patients have to do to manage their health and how this is not recognised by clinical guidelines. The editors also talk about the non-drug management of low back pain and discuss a case of metformin-associated lactic acidosis precipitated by liraglutide use. Read the full issue: dtb.bmj.com/content/57/7.

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In June's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) consider the European Medicines Agency's decision to amend the licence for omega-3 fatty acid medicines so that they will no longer be authorised for secondary prevention after myocardial infarction. The editors also review ospemifene, a new medicine for the management of vulvar and vaginal atrophy and discuss a case of delusional infestation in the treatment of ADHD with atomoxetine. Read the full issue: https://dtb.bmj.com/content/57/6.

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In May's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the opportunities for drugs and therapeutics in the new GP contract for England. The editors also talk about the management of chronic cough and discuss a case of acute liver failure associated with a short course of nitrofuantoin. Read the issue online: https://dtb.bmj.com/content/57/5.

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In April's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the challenges of prescribing direct acting oral anticoagulant (DOAC) drugs for people with renal impairment. The editors also talk about the use of saline nasal irrigation and discuss central sensitisation syndrome. Read the issue online: https://dtb.bmj.com/content/57/4.

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In March's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) get excited about the impact that the results of the Direct study could have on the management of type 2 diabetes. The editors also discuss the combination of doxylamine and pyridoxine for the treatment of nausea and vomiting in pregnancy and consider the role of primary care in supporting patients who are taking clozapine. Read the full issue: https://dtb.bmj.com/content/57/3.

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In February's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of inhaled corticosteroids in the management of COPD (https://dtb.bmj.com/content/57/2/18). The editors also consider subclinical hypothyroidism in pregnancy (https://dtb.bmj.com/content/57/2/22) and discuss Gilbert’s syndrome (https://dtb.bmj.com/content/57/2/27). Read the full issue: https://dtb.bmj.com/content/57/2

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In January's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether intravenous antibiotics are always needed. The editors also consider the challenge of stopping antipsychotic drug treatment in people with intellectual disability and review a case of angioedema of the small bowel caused by lisinopril. Read the issue: dtb.bmj.com/content/57/1.

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In December's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the conditional authorisation process for medicines and the need for clearer labelling of medicines that have been through this approval processes. The editors also consider common sources of information on medicines for patients and review a case of interstitial lung disease associated with adalimumab. Read the issue: https://dtb.bmj.com/content/56/12.

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In November's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a recent study that compared a coordinated, multi-professional, multi-faceted primary care approach to managing people with multiple long-term conditions with usual general practice care. The editors also consider problems faced by patients who need to travel overseas with controlled drugs and review a case of splenic rupture associated with rivaroxaban. Read the November issue: https://dtb.bmj.com/content/56/11.

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In October's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the place of population screening for atrial fibrillation and the need for more evidence to support a change in national policy (https://dtb.bmj.com/content/56/10/112). The editors also consider problems associated with long-term opioid use in the management of chronic pain (https://dtb.bmj.com/content/56/10/118). Please watch the video about Michael's moving story on this subject at dtb.bmj.com. The launch of slidenafil as an over-the-counter pharmacy medicine (https://dtb.bmj.com/content/56/10/123) is also discussed. Read the latest from the reinvented Drug and Therapeutics Bulletin here: dtb.bmj.com.

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In September's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) highlight some of the changes to DTB that have taken place this month and discuss the background and rationale to these changes. Read this month's editorial: https://dtb.bmj.com/content/56/9/98. The editors also consider the place for monitored dosage systems (https://dtb.bmj.com/content/56/9/102) and discuss the evidence for using labetalol as a first-line treatment option for hypertension in pregnancy (https://dtb.bmj.com/content/56/9/107). Meet the new DTB here: https://dtb.bmj.com/content/56/9.

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In the August's podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the results of an awarding research paper that assessed the impact of spending the second stage of labour either in a recumbent or upright position. Read the editorial: https://dtb.bmj.com/content/56/8/85. The editors also consider nutritional support in primary care (https://dtb.bmj.com/content/56/8/90) and discuss new licensing pathways that provide faster access to medicines (https://dtb.bmj.com/content/56/8/93).

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In July’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the risk of drug interactions with herbal medicines. Read the editorial: https://dtb.bmj.com/content/56/7/73. The editors also review the evidence for ocrelizumab for relapsing MS and early primary progressive MS (https://dtb.bmj.com/content/56/7/80), and discuss the role of metformin in people with type 1 diabetes (https://dtb.bmj.com/content/56/7/78).

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In the June’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss whether a recently published large meta-analysis on the effectiveness of antidepressants tells us anything new. Read the editorial here: dtb.bmj.com/content/56/6/61. The editors also review the evidence for the combination analgesic of tramadol/dexketoprofen (dtb.bmj.com/content/56/6/66), and question the dose of paracetamol for older people (dtb.bmj.com/content/56/6/69).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the evidence for pulmonary rehabilitation for COPD and highlight the need for more publicity for its benefits. Read the editorial here: http://dtb.bmj.com/content/56/5/49. The editors also review the evidence for safinamide for Parkinson’s disease (http://dtb.bmj.com/content/56/5/54), and discuss the use of bezlotoxumab, a monoclonal antibody licensed for the prevention of recurrence of Clostridium difficile infection in adults who are at high risk of recurrence (http://dtb.bmj.com/content/56/5/57).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a national campaign in England that is tackling the inappropriate use of antipsychotic and antidepressant medicines in people with learning or intellectual disability. Read the article: http://dtb.bmj.com/content/56/4/37. The editors also review the evidence for a once-daily triple inhaler for maintenance treatment for adults with moderate to severe COPD (http://dtb.bmj.com/content/56/4/42), and discuss off-label use of high-dose antihistamines for chronic spontaneous urticaria in adults (http://dtb.bmj.com/content/56/4/45).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss some of the difficulties in implementing clinical guidelines for the management of elevated blood pressure and the potential impact of changes in the threshold for a diagnosis of hypertension (http://dtb.bmj.com/content/56/3/25). The editors also review the evidence for dupliumab for the treatment of moderate-to-severe atopic dermatitis in adults (http://dtb.bmj.com/content/56/3/30) and discuss drug names (http://dtb.bmj.com/content/56/3/33). Read the full March 2018 issue here: http://dtb.bmj.com/content/56/3.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the importance of developing patient decision aids to support the implementation of clinical guidelines (http://dtb.bmj.com/content/56/2/13). The editors also review the evidence for cladribine for the treatment of highly active relapsing multiple sclerosis (http://dtb.bmj.com/content/56/2/21) and discuss the latest levonorgestrel IUS device to be marketed for contraception (http://dtb.bmj.com/content/56/2/18).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the importance of exercise, diet and behaviour modification in the management of obesity and consider the limitations of anti-obesity drugs. http://dtb.bmj.com/content/56/1/1

The editors also review the evidence for ▼patiromer, a cation exchange polymer, that has recently been marketed for the management of hyperkalaemia - http://dtb.bmj.com/content/56/1/6 and discuss the management of gout. http://dtb.bmj.com/content/56/1/9

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the challenge of prescribing specialist drugs in primary care and highlight problems associated with the use of shared care protocols. http://dtb.bmj.com/content/55/12/133

The editors also review the evidence for an inhaler containing beclometasone, formoterol and glycopyrronium that has recently been licensed for the management of COPD - http://dtb.bmj.com/content/55/12/138 - and discuss the use of dimethyl fumarate for psoriasis. http://dtb.bmj.com/content/55/12/141

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the challenges associated with prescribing for long-term conditions in women who are pregnant and raise concerns that medicines may be stopped inappropriately. Read the editorial here: http://dtb.bmj.com/content/55/11/121. The editors also review a combination product containing naltrexone and bupropion that is licensed for the management of obesity - http://dtb.bmj.com/content/55/11/126 - and discuss bleeding risks associated with direct oral anticoagulants (DOACs)- http://dtb.bmj.com/content/55/11/129. http://dtb.bmj.com/

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the fragmented approach to communicating additional risk minimisation measures for medicines. Article available here: http://dtb.bmj.com/content/55/10/1.

The editors also review the long-term safety of PPIs (http://dtb.bmj.com/content/55/10/117) and discuss the use of the live attenuated influenza vaccine for children (http://dtb.bmj.com/content/55/10/114).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss vitamin D deficiency in teenagers and highlight the challenge of implementing national recommendations on vitamin D intake in young people. Full article here: http://dtb.bmj.com/content/55/9/1.

The editors also review the management of scarlet fever (http://dtb.bmj.com/content/55/9/102.2) and consider two drugs (baricitinib and tofacitinib) recently licensed for the management of rheumatoid arthritis (http://dtb.bmj.com/content/55/9/102.1).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the supply of medicines from online primary care services (article here: http://dtb.bmj.com/content/55/8/85).

The editors also review two recently licensed drugs: eluxadoline, a mixed opioid receptor agonist/antagonist for irritable bowel syndrome (http://dtb.bmj.com/content/55/8/90) and an oral formulation of glycopyrronium (http://dtb.bmj.com/content/55/8/93) for severe drooling in children.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the role of Electroconvulsive Therapy (ECT) in the management of psychiatric disorders. Article here: http://dtb.bmj.com/content/55/7/1.

The editors also discuss the use of liraglutide for obesity (related article here: http://dtb.bmj.com/content/55/7/78)and highlight some of the challenges associated with the management of people with clinical features of both asthma and COPD (http://dtb.bmj.com/content/55/7/66).

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of high-dose inhaled corticosteroids in asthma and COPD.

The editors also highlight some of the challenges associated with the management of superficial venous thrombosis of the leg and discuss the use of carbohydrate deficient transferrin as a biomarker for the assessment of chronic alcohol use.

Read more about the DTB's June 2017 issue: http://dtb.bmj.com/content/55/6#DTBSelect. Editorial: http://dtb.bmj.com/content/55/6/61. Related articles: http://dtb.bmj.com/content/55/6/66 and http://dtb.bmj.com/content/55/6/69.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss attempts by the NHS in England to target £400m of prescribing expenditure that is reported to be wasted on a range of products that are considered to be of low value. Editorial available here: http://dtb.bmj.com/content/55/5/49

The editors also review the evidence for the use of off-label testosterone supplementation in menopausal women (http://dtb.bmj.com/content/55/5/57) and discuss a new formulation of the topical antiseptic dequalinium (http://dtb.bmj.com/content/55/5/54) that is licensed for treatment of bacterial vaginosis.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a national initiative to identify and manage people at high risk of developing type 2 diabetes. Full article available here: http://dtb.bmj.com/content/55/4/37.

The editors also review the evidence for an HRT product containing bazedoxifene and conjugated oestrogens (http://dtb.bmj.com/content/55/4/42) and discuss a new formulation of lidocaine and prilocaine licensed for treatment of premature ejaculation (http://dtb.bmj.com/content/55/4/45).

The highlights of the DTB April 2017's issue here: http://dtb.bmj.com/content/55/4/38.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss some of the implications related to funding of pre-exposure prophylaxis (PrEP) for human immunodeficiency virus (HIV). They consider the Court of Appeal decision on funding and the role of clinical and health economic evaluations for preventative treatments. Full article available here: http://dtb.bmj.com/content/55/3/25.

The editors also review the evidence for a new formulation of desmopressin for nocturia in adults (http://dtb.bmj.com/content/55/3/30) and discuss penicillin allergy (http://dtb.bmj.com/content/55/3/33).

Find out more about the March issue here: http://dtb.bmj.com/content/55/3/26.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the risk of hyperkalaemia associated with spironolactone in people with heart failure. They consider recent advice issued by the Medicines and Healthcare products Regulatory Agency and highlight the importance of regular monitoring of potassium and renal function.

The editors also review the evidence for daclizumab, a drug for relapsing multiple sclerosis, and provide a brief introduction to the rationale and methods of qualitative research in health care.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss a proposal from NHS England to introduce a sore throat test-and-treat service in community pharmacies. They review the evidence on the management of sore throat and examine the assumptions that underpin the proposed service.

The editors also discuss pitolisant, a new drug for narcolepsy, and review the evidence for LAMA/LABA inhaler combinations for people with COPD.

Read more about this issue here: http://dtb.bmj.com/content/55/1.toc.

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"Clarity begins at home". In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) start by remembering DTB's founding editor, Andrew Herxheimer's golden rules for prescribing.

The DTB editors also discuss 'gliptins' in the management of diabetes and evidence from recent cardiovascular outcome studies, as well as, psychological interventions for eating disorders.

The full editorial is available here: http://dtb.bmj.com/content/early/2016/12/05/dtb.2016.12.0439.full. You can also watch the video interview with Andrew Herxheimer here: http://tinyurl.com/jybvocp.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss changes to the rubella screening programme and the need to ensure that MMR vaccinations are up to date, especially in younger women born outside the UK. Read the full editorial here: http://dtb.bmj.com/content/54/11/121.full.

The editors also discuss prescribing information sources (http://dtb.bmj.com/content/54/11/129.full) and the evidence on the management of difficult to treat severe asthma (http://dtb.bmj.com/content/54/11/126.full).

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Why should we worry about the new European Medicines Agency (EMA) pilot project to accelerate the approval of new drugs? James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the October issue Editorial, that looks at the pros and cons of this new trend both in the USA and Europe. Read the full article here: http://dtb.bmj.com/content/54/10/109.full.

Also in this podcast: • the use of the new antibiotic Fosfomycin trometamol for the treatment of acute uncomplicated lower urinary tract infections (UTIs) –http://dtb.bmj.com/content/54/10/114.abstract; • as well as the "health condition" of point-of-care tests for respiratory tract infections (RTI) in improving diagnosis capabilities in GP surgeries - http://dtb.bmj.com/content/54/10/117.full.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of nalmefene in the management of alcohol dependence. Although the drug has been approved for use in the NHS, DTB's editorial highlights limitations of the evidence supporting its use and discusses concerns raised by three groups of researchers. Currently, the NHS in England spends £20,000 per month on the drug in primary care. Read the full editorial here: http://dtb.bmj.com/content/54/9/97.full.

There’s also a review of the management of hidradenitis suppurativa. Article accessible here: http://dtb.bmj.com/content/54/9/102.full.

The DTB editors also talk about the benefits and limitations of observational studies. Article accessible here: http://dtb.bmj.com/content/54/9/105.full.

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In this month’s podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the presentation of guidelines and ways of making them more accessible. Read the full editorial here: http://dtb.bmj.com/content/54/8/85.full

There’s also an evaluation of the use of capsaicin for diabetic peripheral neuropathy. Article accessible here: http://dtb.bmj.com/content/54/8/90.full

The DTB editors also talk about medicines, excipients and dietary intolerances. Article accessible here: http://dtb.bmj.com/content/54/8/93.full

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss proposals to stop the prescription of some medicines and foods in order to help manage the deficit in NHS budgets. Full article available here: http://dtb.bmj.com/content/early/2016/07/07/dtb.2016.7.0409.full.

The podcast also includes a review of an article about the effects of the antidiabetic drug empagliflozin on cardiovascular outcomes, as well as a review of an article on the use of vitamin supplementation during pregnancy. Read this article here: http://dtb.bmj.com/content/early/2016/07/11/dtb.2016.7.0414.full.

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the use of herbal products. They also develop the highlights of the articles: Articles: "Frailty, polypharmacy and deprescribing" and "Sacubitril valsartan for heart failure"

Read all the articles featured here: dtb.bmj.com/content/54/6.toc

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss health checks for young people with learning disabilities and review two recently licensed drugs - one for treating orthostatic hypotension and the other for managing ADHD in children and adolescents.

Read all the articles featured here: dtb.bmj.com/content/54/5.toc

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the Cancer Drug Fund for England; review a new indication for the combination of oxycodone and naloxone for the management of restless legs syndrome; and consider the impact of animal-derived medicines. Read the articles featured here:

Editorial: NICE and the cancer drugs fund for England Articles: 1. Targinact for restless legs syndrome 2. Implications of religious and cultural beliefs on selection of medicines

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss testosterone replacement therapy; review the new antidepressant vortioxetine; and consider the impact of drugs on the QT interval.

The DTB podcast is recorded monthly to coincide with the release of the print issue of DTB.

Read all the articles featured here: dtb.bmj.com/content/54/3.toc

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss the proliferation of new drugs for managing COPD; review two new lipid-lowering drugs (evolocumab and alirocumab) from a new class (proprotein convertase subtilisin/kexin type 9 inhibitors); and consider total ankle joint replacement.

The DTB podcast is recorded monthly to coincide with the release of the print issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/54/2.toc

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss NHS Health Checks in England; the challenges facing young people taking medicines for long-term conditions; and the management of dry eye disease.

The DTB podcast is recorded monthly to coincide with the release of the print issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/54/1.toc

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In this podcast, James Cave (DTB Editor-in-Chief) and David Phizackerley (DTB Deputy Editor) discuss stopping rules for medicines used to manage long-term conditions; naloxegol for the management of opioid-induced constipation that has failed to respond to laxative therapy; and the plethora of new drugs and preparations for the management of open-angle glaucoma in adults.

The DTB podcast is recorded monthly to coincide with the release of the print issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/12.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the November 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/11.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the September 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/9.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the October 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/10.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the August 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/8.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the July 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/7.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the June 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/6.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the May 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/5.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the April 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/4.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the February 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/3.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the March 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/3.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the January 2015 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/53/1.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the December 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/12.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and Caroline Blaine (DTB Clinical Editor) discuss the contents of the October 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/11.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the October 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/10.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the September 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/9.toc

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Welcome to the DTB podcast, which is recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the August 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/8.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the July 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/7.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the June 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/6.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the May 2014 issue of DTB.

Read all the articles featured here: http://dtb.bmj.com/content/52/5.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the April 2014 issue of DTB:

Metformin OK in CKD? Lubiprostone for chronic constipation in adults Management of adults with PTSD part II: drugs and other interventions EMA to review efficacy of emergency contraceptives

Read them all here: dtb.bmj.com/content/52/4.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the February 2014 issue of DTB:

Editorial - Describing deprescribing

Article - Dapoxetine for premature ejaculation

Article - Management of adults with PTSD

DTB Select - Further restrictions on the use of strontium ranelate

Read all the articles here: dtb.bmj.com/content/52/3.toc

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Welcome to a new series of DTB podcasts that are being recorded monthly to coincide with the release of the print issue of DTB.

James Cave (DTB Editor in Chief) and David Phizackerley (DTB Deputy Editor) discuss the contents of the February 2014 issue of DTB:

Editorial - What price change?

Article - Interactions with herbal products: what do we know?

Article - Azelastine and fluticasone nasal spray: any advantage?

DTB Select - Cardiovascular risk with medicines containing sodium

dtb.bmj.com

Read all the articles here: http://dtb.bmj.com/content/52/2.toc

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A monthly audio round-up detailing the contents of the latest issue of DTB.

HIV services - what role for primary care?

DTB Select: 7 - August 2011

The place of routine HIV testing

What role for ▼prucalopride in constipation?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Adults with ADHD: ignored and under treated

DTB Select: 6 - July 2011

Management of acute infective conjunctivitis

Systemic lupus erythematosus - an update

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This month’s issue considers whether use of sunscreens helps to prevent skin cancer.

This podcast focuses on these topics and related issues, and involves discussion between Brian Diffey (Emeritus Professor of Photobiology at Newcastle University), Ike Iheanacho and David Phizackerley (Editor and Deputy Editor, DTB, respectively).

Accompanying this is an editorial that questions recent public health guidance on sunscreens from the National Institute for Health and Clinical Excellence.

Articles:

Sunscreen SPFs: clear as daylight?

Do sunscreens have a role in preventing skin cancer?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Sunscreen SPFs: clear as daylight?

DTB Select: 5 | June 2011

▼Ticagrelor for acute coronary syndrome?

Do sunscreens have a role in preventing skin cancer?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

PPIs: too much of a good thing?

DTB Select: 4 | May 2011

Managing diffuse oesophageal spasm

Nanomedicines - what are they?

Update: Artemisinins in malaria treatment in the UK

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Herbal medicine - all change

DTB Select: 3 | April 2011

Curing patients with liver metastases from colorectal cancer

Roflumilast for severe COPD?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Don’t bank on savings

DTB Select: 2 | March 2011

OTC tranexamic acid for heavy menstrual bleeding – an update

Post-exposure prophylaxis for HIV

Pain management programmes for chronic pain?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Polypillomania

DTB Select: 1 ∣ February 2011

Reducing NSAID-induced gastrointestinal complications

Botox for chronic migraine

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Playing the numbers game

Can beta-blockers be used for people with COPD?

OTC tranexamic acid for heavy menstrual bleeding?

Which oral aminosalicylate for ulcerative colitis?

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

60 and counting

Which insulin, regimen and device in type 2 diabetes?

Targinact – opioid pain relief without constipation?

What role for topical antibacterials in acne?

Don’t Drop Mixtard 30 campaign: Thank you

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Price, pragmatism and prasugrel

Seasonal flu vaccination for healthcare workers?

Dronedarone for atrial fibrillation?

Artemisinins in malaria treatment in the UK

Don’t Drop Mixtard 30: what people say

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Back to the future

The use of ‘specials’ in primary care

OTC tamsulosin for benign prostatic hyperplasia

Do corticosteroids improve outcome in meningitis?

Mixtard 30: time’s running out

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

The price you pay

Management of corticosteroid-induced osteoporosis

What role for Qlaira in contraception?

A guide to health economic evaluations

Don’t Drop Mixtard 30 campaign

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As part of DTB’s “Don’t Drop Mixtard” campaign, this podcast discusses the implications of the drug’s withdrawal from the UK market for people with diabetes, healthcare professionals and the NHS.

The conversation involves Dr Wing May Kong (consultant endocrinologist and member of the DTB Editorial Board), Cathy Moulton (Care Adviser at Diabetes UK), and Dr Ike Iheanacho and David Phizackerley (Editor and Deputy Editor of DTB, respectively).

To find out more about the campaign, including DTB’s petition against the withdrawal of Mixtard 30, please go to dtb.bmj.com.

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Mixtard 30 - going, going, gone?

Ulipristal – a new emergency contraceptive pill

Management of fibromyalgia

Agomelatine for major depressive episodes

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Money, money, money

Preventing exacerbations in COPD

Febuxostat for gout

How medical devices are regulated in the UK

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Why pregabalin? DTB 2010; 48: 61

Acupuncture for tension-type headaches and migraine DTB 2010; 48: 62 - 5

Misoprostol for postpartum haemorrhage DTB 2010; 48: 66 - 9

Testosterone for ‘late-onset hypogonadism’ in men? DTB 2010; 48: 69 - 72

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Alcoholic neglect DTB 2010; 48: 49

Liraglutide for type 2 diabetes? DTB 2010; 48: 50 - 3

Grazax for hay fever – what’s new? DTB 2010; 48: 54 - 6

I.V. immunoglobulin therapy for infectious diseases DTB 2010; 48: 57 - 60

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

The computer says “no”? DTB 2010; 48: 37

Silver dressings – do they work? DTB 2010; 48: 38 - 42

Vagus nerve stimulation for epilepsy DTB 2010; 48: 42 - 45

Herbal medicines – what do clinicians know? DTB 2010; 48: 46 - 47

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This month, we publish the results of a Drug and Therapeutics Bulletin Survey on Herbal Medicines, an online research designed to explore healthcare professionals’ knowledge of and attitudes towards herbal medicines. In this podcast, Dr Ike Iheanacho, DTB Editor, and David Phizackerley, DTB Deputy Editor, discuss the results of the survey, and issues related to the use and regulation herbal medicines, with Dr Linda Anderson, Principal Pharmaceutical Assessor at the MHRA and Mr Michael McIntyre, Chairman of the European Herbal and Traditional Medicine Practitioners Association. The results of DTB Survey on Herbal Medicines are available on our website, dtb.bmj.com.

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

A risky business? DTB 2010; 48: 25

Using NSAIDs in cardiovascular disease DTB 2010; 48: 26 - 29

Managing primary hyperparathyroidism in primary care DTB 2010; 48: 30 - 33

Body surface area for adjustment of drug dose DTB 2010; 48: 33 - 36

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Patient safety first? DTB 2010; 48: 13

Management of community-associated MRSA DTB 2010; 48: 14 - 19

▼Pregabalin for generalised anxiety disorder DTB 2010; 48: 19 - 22

A change of units for HbA1c DTB 2010; 48: 23 - 24

Conversion chart for HbA1c values

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

More on high street mole checks DTB 2010; 48: 1

Management of medication overuse headache DTB 2010; 48: 2 - 6

Cognitive behavioural therapy for schizophrenia DTB 2010; 48: 6 - 9

Tocilizumab for rheumatoid arthritis DTB 2010; 48: 9 - 12

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

C. difficile outside hospital DTB 2009; 47: 133

Managing gastro-oesophageal reflux in infants DTB 2009; 47: 134 - 137

Strong opioids for osteoarthritis in primary care? DTB 2009; 47: 138 - 141

Generic prescribing in epilepsy DTB 2009; 47: 141 - 144

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Uncommon knowledge DTB 2009; 47: 121

Aspirin for primary prevention of cardiovascular disease? DTB 2009; 47: 122 - 125

Over-the-counter weight loss with orlistat? DTB 2009; 47: 125 - 127

Management of seasonal affective disorder DTB 2009; 47: 128 - 132

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Generically speaking DTB 2009; 47: 109

Does BNP testing aid diagnosis of heart failure? DTB 2009; 47: 110 - 113

Imiquimod for superficial and in situ skin malignancy DTB 2009; 47: 113 - 116

Anticoagulation with dabigatran or rivaroxaban DTB 2009; 47: 116 - 120

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The widespread use of oseltamivir (Tamiflu) has been a key strategy in tackling the H1N1 ‘swine flu’ pandemic in the UK. However, there have been growing concerns about the communication of this approach and rationale behind the policy itself. In this podcast Dr Ike Iheanacho, DTB editor, discusses the policy with two members of the DTB editorial board, Dr Paul Caldwell, a general practitioner and Dr Mahdad Noursadeghi, an infectious diseases consultant. This is an extension of our September 2009 Editorial, Tamiflu − the wrong message? DTB 2009; 47: 97.

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Tamiflu − the wrong message? DTB 2009; 47: 97

Self-monitoring for patients on warfarin? DTB 2009; 47: 98 - 101

Non-drug management of chronic low back pain DTB 2009; 47: 102 - 108

Correction: How to misinform patients DTB 2009; 47: 108

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

How to misinform patients DTB 2009; 47: 85

Management of carpal tunnel syndrome DTB 2009; 47: 86 - 89

So, what exactly is a cytokine? DTB 2009; 47: 89 - 91

Ezetimibe – an update DTB 2009; 47: 91 - 95

Understanding statistical terms: 5 – systematic reviews and meta-analyses DTB 2009; 47: 95 - 96

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Only in England DTB 2009; 47: 73

Melatonin for primary insomnia? DTB 2009; 47: 74 - 77

Which approach for first trimester miscarriage? DTB 2009; 47: 77 - 80

What are excipients doing in medicinal products? DTB 2009; 47: 81 - 84

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

Real costs of end-of-life drugs DTB 2009; 47: 61

Management of benign paroxysmal positional vertigo DTB 2009; 47: 62 - 66

Interferon-gamma release assays and TB diagnosis DTB 2009; 47: 67 - 70

Understanding statistical terms: 4 – Diagnostic tests DTB 2009; 47: 71 - 72

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In January 2009, NICE began a policy for valuing the use of drugs for extending life in people with a short life-expectancy. This development arose from concerns that NICE had been denying patients life-extending treatments because they were too expensive. However, the new policy also raises important ethical and moral dilemmas. In this podcast Dr Martin Duerden, General Practitioner and member of the DTB editorial board, and Dr Ike Iheanacho, DTB Editor, discuss this policy and the issues it raises. This is an extension of our June 2009 Editorial, Real costs of end-of-life drugs DTB 2009; 47: 61.

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

The mad world of epilepsy drugs DTB 2009; 47: 49

Update on treatments for head lice DTB 2009; 47: 50 - 52

What role for colesevelam in cardiovascular prevention? DTB 2009; 47: 53 - 5

Why look at an SPC? DTB 2009; 47: 56 - 58

Understanding statistical terms: 3 DTB 2009; 47: 59 - 60

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A monthly audio round-up detailing the contents of the latest issue of DTB.

Articles:

What are you on? DTB 2009; 47: 37

Preventing recurrent venous thromboembolism. DTB 2009; 47: 38 - 41

Drospirenone in HRT? DTB 2009; 47: 41 - 4

The licensing of medicines in the UK. DTB 2009; 47: 45 – 48

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Drugs prescribed and administered solely under specialist care or as part of clinical trials, without being specifically recorded in GPs’ prescribing systems, can have serious consequences for patient safety. Here, in our second podcast, Dr Pawan Randev, general practitioner and primary care cancer lead, and Dr Ike Iheanacho, DTB Editor, discuss these issues. This is an extension of our April 2009 Editorial, What are you on? (DTB 2009; 47: 37).

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Early diagnosis in malignant melanoma is crucial to long-term survival. With this knowledge have come new imaging technologies for assessing suspect pigmented lesions. These, in turn, have led to privately run ‘high street mole clinics’. Here, in our first podcast, Dr Julia Schofield, Principal Lecturer in Dermatology at the University of Hertfordshire and member of the DTB editorial board, and Dr Ike Iheanacho, DTB Editor, discuss the place of these clinics. This is an extension of our March 2009 Editorial, Mole checks on the high street (DTB 2009; 47: 25).

DTB articles you may be interested in:

Mole checks on the high street. DTB 2009; 47: 25

Minocycline for acne – an update. DTB 2009; 47: 7 - 8

How should fungal nail infection be treated? DTB 2008; 46: 3 - 8

Managing scalp ringworm in children. DTB 2007; 45: 89 - 92

Bath emollients for atopic eczema: why use them? DTB 2007; 45: 73 - 5