As Denmark has not had an foot and mouth disease (FMD)-outbreak since 1983, the objective of this study was to use epidemiological modelling to compare the effects of a set of different mitigation measures on e.g. predicted number of infected and culled herds, and epidemic control duration1. The epidemiological impact of basic mitigation measures was compared to additional mitigation strategies on top of the basic measures. Additionally, the geographical influence and the impact of specific cattle production systems as index herds were analysed in terms of the predictive variables.