indiaviagra
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Erection of the penis is a hemodynamic process based on the relaxation of the smooth muscles of cavernous bodies and the arterioles located in it. During sexual stimulation, nitrogen oxide (N0) is excreted from the nerve endings of cavernous bodies, which activates the guanilatcycle enzyme, leading to an increase in the content of cyclic guanosine monophosphate (cGMP) in cavernous bodies. As a result, smooth muscles of cavernous bodies are relaxed, which increases blood flow into the penis. The level of cGMF is regulated by the synthesis of guanylate cyclase on the one hand, and by the cleavage of cGMF by phosphody-esterase hydrolysis (PDE) on the other. The most well-known PDE is cGMF specific phosphodiester-type 5 (PDE5).
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