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Ralph Turchiano
My Personal Biomedical Research Feed - Ralph Turchiano, CEO Alchepharma Support this podcast: https://anchor.fm/ralph-turchiano/support
The present study demonstrates that green tea extract and ginger supplementation, individually and in combination, enhanced endurance performance, metabolic efficiency, and thermal perception in recreationally active males under normothermic and cold conditions. Green tea alone increased time to exhaustion and reduced respiratory exchange ratio in normothermic conditions, indicating improved fat oxidation and endurance capacity. In cold conditions, the combination of green tea and ginger enhanced time to exhaustion, lowered the respiratory exchange ratio, improved thermal sensation, and reduced muscle soreness. These effects are most pronounced in cold environments, where the combined supplementation mitigated the heightened physiological demands of cold exposure while amplifying metabolic benefits. To our knowledge, this is the first randomized, double-blind crossover trial to systematically evaluate the supportive combined effects of green tea and ginger across different environmental conditions.
A 2025 study in the journal Nutrients investigated the effects of green tea extract and ginger on endurance performance in different temperatures. In a randomized, double-blind crossover trial, sixteen recreationally active males were tested under eight different conditions. The conditions included taking a placebo, 500 mg of green tea extract, 1000 mg of ginger, or a combination of both, each in normal (normothermic) and cold environments (
). In normal temperatures, both green tea alone and the combined supplement significantly increased the time-to-exhaustion (endurance) and reduced the respiratory exchange ratio (RER), indicating greater fat oxidation, compared to the placebo. In cold conditions, the combination of green tea and ginger was most effective, significantly enhancing endurance, improving thermal sensation (feeling warmer), and reducing RER compared to both placebo and ginger alone. All active supplements (green tea, ginger, and combined) also significantly decreased muscle soreness 24 hours after exercise in the cold compared to the placebo.
Disclaimers:
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed was conducted on a small sample of 16 recreationally active males. The findings cannot be extrapolated to women, older adults, or competitive athletes, and further research is needed."
•"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
•"This channel is not monetized and does not provide medical advice."
•(Reminder: Please include a verbal disclaimer in the video itself.)
GreenTea #Ginger #EndurancePerformance #ColdEnvironment #FatOxidation
Demirli, A.; Ulupınar, S.; Terzi, M.; Özbay, S.; Özkara, A.B.; Gençoğlu, C.; Ouergui, L; Ardigò, L.P. Synergistic Effects of Green Tea Extract and Ginger Supplementation on Endurance Performance and Thermal Perception in Normothermic and Cold Environments: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial. Nutrients 2025, 17, 2949. https://doi.org/10.3390/nu17182949.
Alchepharma,Ralph Turchiano,citation,research,study,green tea extract,ginger supplementation,endurance performance,cold environment,normothermic,thermal perception,fat oxidation,time to exhaustion,perceived exertion,muscle soreness,synergistic effects,catechins,epigallocatechin gallate,gingerols,ergogenic aids,thermogenesis,randomized controlled trial,crossover trial,exercise physiology,submaximal exercise,VO2 max,sports nutritionNarrator: Ralph Turchiano, AlchePharma CEO
A major scientific review looked at the best available evidence on apple cider vinegar (ACV) and its effects on body weight. Researchers combined the results from 9 different studies that included adults who were overweight, obese, or had type 2 diabetes.
Here’s what they found:
•Taking ACV daily was linked to a significant drop in body weight, BMI, and waist size.
•The authors calculated this could amount to an average weight loss of about 7.4 kg (over 16 pounds).
•The most effective approach seemed to be taking about two tablespoons (30 mL) per day for up to 12 weeks.
The main takeaway is that science suggests ACV may be a helpful tool for short-term weight management.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed is a meta-analysis of randomized controlled trials conducted on adult humans who were overweight, obese, or had type 2 diabetes. The intervention periods in the included studies were relatively short, ranging from 4 to 12 weeks."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
AppleCiderVinegar #WeightLoss #BodyComposition #MetaAnalysis #ObesityResearch
Source Article Citation:
Castagna, A.; Ferro, Y.; Noto, F.R.; et al. Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients 2025, 17, 3000. DOI: https://doi.org/10.3390/nu17183000
Apple cider vinegar, ACV, acetic acid, weight management, body composition, obesity, overweight, type 2 diabetes, meta-analysis, randomized controlled trial, RCT, body weight, BMI, body mass index, waist circumference, visceral adiposity, anthropometric measurements, weight loss, dietary supplement, short-term weight management, metabolic health, adiposity, nutritional intervention, systematic review, dose-response
A recent randomized, double-blind, placebo-controlled study published in the journal Nutrients investigated the effects of Cistanche deserticola (CD) supplementation on muscle strength and recovery. The eight-week trial involved 48 male participants, who were divided into resistance-trained and untrained groups. Participants in the intervention group received 5 g of CD extract twice daily, for a total of 10 g per day, while following a standardized resistance training program three times per week.
Among untrained individuals, the CD group showed significantly greater improvements in 1RM bench press, 1RM squat, maximal voluntary isometric contraction (MVIC), and repetitions to failure (RTF) compared to the placebo group. Furthermore, the CD group exhibited significantly improved recovery markers, including increased serum testosterone and decreased levels of cortisol, C-reactive protein (CRP), and creatine kinase (CK). In the trained group, CD supplementation led to significant increases in 1RM squat strength and MVIC. While upper body strength and endurance gains were not statistically different from the placebo group, the trained CD group still showed significantly better recovery markers, including improved testosterone and cortisol levels and marked reductions in CRP and CK. The authors concluded that eight weeks of CD supplementation effectively enhanced muscle strength and facilitated post-exercise recovery.
Disclaimers:
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed was conducted on healthy male participants (both resistance-trained and untrained). Further research may be needed to confirm these findings in other populations."
•"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
•"This channel does not provide medical advice."
CistancheDeserticola #MuscleStrength #ResistanceTraining #MuscleRecovery #SportsNutrition
Tao B, Lian W, Min R, Zhang X, Chen L, Hao S, Li Z, Ma C, Zhang H, Liu C. Effects of Cistanche deserticola Y.C. Ma Supplementation on Muscle Strength and Recovery: A Randomized Controlled Trial. Nutrients. 2025; 17(18):2965. https://doi.org/10.3390/nu17182965
Alchepharma,Ralph Turchiano,citation,research,study,Cistanche deserticola,Desert Ginseng,muscle strength,muscle recovery,resistance training,testosterone,cortisol,creatine kinase,C-reactive protein,randomized controlled trial,ergogenic aid,sports nutrition,phenylethanoid glycosides,echinacoside,acteoside,traditional Chinese medicine,strength gains,muscle endurance,post-exercise recovery,hormonal response,inflammation markers,1RM bench press,1RM squat
A new study in the journal Food Quality and Preference investigated if increasing the spiciness of a meal could influence eating behaviors and reduce how much food people consume. In a series of experiments, researchers had adults eat either a mild or a spicy version of beef chili or chicken tikka masala in a lab setting. The results were significant: when participants ate the spicy beef chili, they consumed 11% less food (about 46 grams) and ate 11% more slowly compared to when they ate the mild version. A similar outcome was observed with a reformulated chicken tikka masala, where the spicy version led to an 18% reduction in food intake (about 64 grams) and a 17% slower eating rate. Interestingly, this reduction in consumption was not because participants liked the spicy food less or drank more water. The findings suggest that the “oral burn” from capsaicin—the active component in chili peppers—directly leads to slower eating and bite rates, which in turn reduces overall food and energy intake.
Disclaimers
This information is for educational purposes only and should not be interpreted as medical advice.
The study discussed was conducted on adults in a controlled laboratory setting. These findings may not apply to different populations or real-world dining situations.
Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.
Capsaicin #EatingRate #FoodIntake #Satiation #Paprika
Cunningham, P. M., Smith, I. M., & Hayes, J. E. (2025). Increasing the spiciness of a lunch meal influences oral processing behaviors and decreases food and energy intake. Food Quality and Preference, 131, 105566.
Capsaicin, paprika, oral burn, spice, chili pepper, eating rate, food intake, energy intake, oral processing, satiation, satiety, ad libitum intake, beef chili, chicken tikka masala, eating behavior, weight management, food formulation, paprika, non-textural manipulation, bite rate, meal duration, food pleasure, calorie reduction, appetite, human study, crossover design
A recent crossover randomized controlled trial published in the journal Nutrients investigated the effects of paprika xanthophylls (PX) on endurance and cognitive function in 21 healthy college students. Participants took a supplement containing 9 mg of PX daily for one month and were compared against a control condition (no intake). The study found significant improvements in physical endurance for the PX group, including higher exercise efficiency during both incremental (p=0.004) and constant load tests (p=0.030). Heart rate was also significantly lower during both the incremental test (p=0.032) and the constant load test (p=0.020). While there were no significant differences between the groups on cognitive tests, the PX group alone showed significant internal improvements in scores on the Trail Making Test Type B (p=0.034) and the Stroop test interference rate I (p=0.040). The authors speculate these benefits may be due to improved oxygen delivery efficiency.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on a small sample of healthy college students and was predominantly male (18 males, 3 females). The authors note the results should be interpreted with caution and may not be generalizable to other populations."
"This study did not use a placebo control group, which is a methodological limitation."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This Channel does not provide medical advice."
PaprikaXanthophyll #EndurancePerformance #CognitiveFunction #ExerciseEfficiency #OxygenDelivery
Kim D, Wadazumi T. Effects of Paprika Xanthophyll Intake on Endurance and Cognitive Function in College Students: A Crossover Randomized Controlled Trial. Nutrients. 2025; 17(17):2780. https://doi.org/10.3390/nu17172780
Alchepharma,Ralph Turchiano,citation,research,study,Paprika xanthophylls,capsanthin,capsorubin,endurance performance,cognitive function,exercise efficiency,oxygen delivery efficiency,DO2,red blood cell deformability,heart rate during exercise,college students,Stroop test,ventilatory threshold,antioxidant supplements,sports nutrition,ergogenic aids,brain oxygenation,executive function,neurocognitive function,microcirculation,athletic performance
A recent study in the journal GeroScience investigated how age-related declines in cellular energy, specifically the molecule Guanosine triphosphate (GTP), affect waste clearance in brain cells. Using hippocampal neurons from an Alzheimer's disease (AD) mouse model, researchers found a significant, age-dependent reduction in free GTP levels, which was accelerated in the AD model neurons. This energy deficit was shown to impair critical cellular processes like endocytosis and autophagy, leading to the accumulation of toxic amyloid-beta (Aß) aggregates and increased protein oxidation. Remarkably, the researchers then treated aged neurons for 24 hours with a combination of nicotinamide (a precursor to the energy-related molecule NAD+) and EGCG (a redox modulator found in green tea). This treatment was highly effective, restoring the depleted GTP levels in aged neurons all the way back to the normal, youthful levels seen in healthy, young neurons. This restoration of cellular energy enhanced the clearance of Aß aggregates and improved the viability of aged AD model neurons by 22%.
Disclaimers
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed was conducted in vitro on neurons isolated from mice. Further research is needed to confirm these findings in humans."
•"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
•"This channel is not monetized and does not provide medical advice."
GTP #Autophagy #AlzheimersResearch #Nicotinamide #EGCG
Source: Santana, R. A., McWhirt, J. M., & Brewer, G. J. (2025). Treatment of age-related decreases in GTP levels restores endocytosis and autophagy. GeroScience. https://doi.org/10.1007/s11357-025-01786-4
Guanosine triphosphate, GTP, Alzheimer's disease, neuronal aging, autophagy, endocytosis, bioenergetics, nicotinamide, EGCG, NAD+, Nrf2, 3xTg-AD mouse model, proteostasis, amyloid-beta clearance, Aß aggregates, mitochondrial dysfunction, cellular energy, redox state, Rab7, Arl8b, neuronal viability, protein oxidation, neurodegeneration, in vitro study, hippocampal neurons
A recent study in Advanced Healthcare Materials reports a novel method for regenerating tooth enamel using water-based films made from keratin, a protein abundant in sources like wool. Researchers found that these keratin films can self-assemble into organized scaffolds that guide the growth of aligned apatite nanocrystals, mimicking natural enamel formation. When applied to artificially created early enamel lesions (white spot lesions), the keratin-based system was able to repair the damage, restoring both the tooth's optical appearance and its mechanical properties. Notably, the mechanical recovery was significant; nanoindentation tests showed the elastic modulus of damaged enamel increased from ~5 GPa back to ~53 GPa, and hardness recovered from ~0.1 GPa to over 1.0 GPa after treatment. These findings present a promising, simple, and potentially low-cost strategy for the clinical treatment of early dental caries.
Disclaimers:
•This information is for educational purposes only and should not be interpreted as medical or dental advice.
•The study discussed was conducted in vitro (on extracted human teeth in a laboratory setting). Further research and human clinical trials are necessary to confirm these findings and evaluate safety and efficacy.
•Always consult with a qualified dental professional before making any changes to your oral healthcare routine or treatment plan.
•This channel does not provide medical advice.
Keratin #EnamelRegeneration #Biomineralization #DentalResearch #RegenerativeDentistry
S. Gamea, E. Radvar, D. Athanasiadou, et al. “ Biomimetic Mineralization of Keratin Scaffolds for Enamel Regeneration.” Adv. Healthcare Mater. (2025): e02465. https://doi.org/10.1002/adhm.202502465
Alchepharma,Ralph Turchiano,citation,research,study,Keratin,enamel regeneration,biomimetic mineralization,apatite nanocrystals,hard tissue regeneration,dental caries,white spot lesion repair,protein scaffolds,self-assembly,spherulites,nanoindentation,Knoop microhardness,tooth decay treatment,regenerative dentistry,biomaterials,apatite nucleation,hierarchical structure,dental tissue engineering,keratin films,in vitro study,restorative dentistry,tooth repair
A study in the journal Nature has uncovered a significant link between the brain's natural lithium levels and Alzheimer's disease (AD). After analyzing 27 different metals in post-mortem human brain tissue, researchers found lithium was the only one significantly reduced in individuals with both mild cognitive impairment (MCI) and AD. The research also showed that amyloid-β plaques, a key marker of AD, trap lithium, which further lowers its availability for use by brain cells.
To confirm this link, scientists conducted experiments on mouse models. They found that reducing the brain's lithium levels by roughly 50% caused an acceleration of AD-like pathology, including increased amyloid-β and phospho-tau deposits, greater neuroinflammation, and a more rapid decline in cognitive function. These effects appear to be driven, at least in part, by the over-activity of a kinase known as GSK3β.
As a potential therapeutic strategy, the team tested a specific salt, lithium orotate (LiO), which is less likely to be sequestered by amyloid plaques. In AD mouse models, low-dose treatment with LiO successfully prevented memory loss and the accumulation of amyloid and tau pathology. The therapy was highly effective, reducing the Aβ plaque burden by about 70% in one model. Furthermore, LiO even reversed age-related memory decline in normal aging mice, pointing to a broader role for lithium in maintaining cognitive health. The findings suggest that a disruption of lithium balance may be a treatable early event in the development of Alzheimer's disease.
Disclaimers
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on human post-mortem brain samples and mouse models. Further research may be needed to confirm these findings in human clinical trials."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications. Lithium can be toxic at high doses and should only be used under medical supervision."
"This channel does not provide medical advice."
Lithium #AlzheimersDisease #NeuroscienceResearch #CognitiveHealth #LithiumOrotate
Aron, L., Ngian, Z.K., Qiu, C., et al. "Lithium deficiency and the onset of Alzheimer's disease." Nature (2025).
A recent network meta-analysis published in the journal
Nutrients systematically compared the effectiveness of seven common nutritional supplements for treating knee osteoarthritis (KOA). The analysis included 39 randomized controlled trials (RCTs) with a total of 4,599 patients. Researchers evaluated the impact of eggshell membrane, vitamin D, Boswellia, curcumin, ginger, krill oil, and collagen against a placebo for improving pain, stiffness, and function. The results showed that compared to a placebo, Boswellia provided statistically significant improvements across all measures, including WOMAC pain (mean difference [MD] = -10.58), stiffness (MD = -9.47), function (MD = -14.00), and VAS pain (MD = -17.26). Bayesian analysis consistently ranked Boswellia as the most likely to be the best option for pain and stiffness relief. Other supplements also showed benefits; krill oil, curcumin, and collagen significantly improved function, while collagen, curcumin, and ginger significantly reduced VAS pain scores. Importantly, no supplement was associated with an increase in adverse events compared to the placebo. The authors conclude that certain supplements, particularly Boswellia, appear to be effective and well-tolerated for managing KOA symptoms.
Disclaimers:
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed is a network meta-analysis of randomized controlled trials conducted on humans. Further research may be needed to confirm these findings."
•"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
#Boswellia #Curcumin #Collagen #KrillOil #Ginger
Zhang Y, Gui Y, Adams R, Farragher J, Itsiopoulos C, Bow K, Cai M, Han J. Comparative Effectiveness of Nutritional Supplements in the Treatment of Knee Osteoarthritis: A Network Meta-Analysis. Nutrients. 2025; 17(15):2547. https://doi.org/10.3390/nu17152547
Alchepharma,Ralph Turchiano,citation,research,study,Knee osteoarthritis,nutritional supplements,Boswellia,curcumin,collagen,ginger,krill oil,eggshell membrane,vitamin D,network meta-analysis,randomized controlled trials,WOMAC pain,WOMAC stiffness,WOMAC function,VAS pain,joint pain relief,osteoarthritis treatment,supplement efficacy,anti-inflammatory supplements
A recent study published in Frontiers in Psychology surveyed 1,082 participants to investigate how food influences sleep and dreams, exploring direct food effects, physiological symptoms (food distress), and altered sleep quality. The study found that 40.2% of participants reported food affecting their sleep, with 24.7% claiming it worsened sleep and 20.1% reporting improvement. Furthermore, 5.5% of participants experienced food-dependent dreaming. The perceived effect of food on dreams was linked to higher nightmare recall and Nightmare Disorder Index scores. Desserts/sweets (31%) and dairy (22%) were most frequently blamed for disturbing dream changes. The study also revealed associations between perceived food-dependent dreaming and food allergies and gluten intolerance, while worse sleep perceptions were tied to lactose intolerance. Importantly, higher Nightmare Disorder Index scores were strongly associated with food allergy and lactose intolerance, with the latter being mediated by the severity of gastrointestinal symptoms. Healthy eating, such as less evening eating, predicted higher dream recall, while unhealthy eating, including gastric symptoms, lower reliance on hunger/satiety cues, and evening eating, predicted nightmares and dream negativity. These findings suggest that food sensitivities, particularly lactose intolerance, can contribute to nightmare prevalence, potentially through gastrointestinal symptoms, opening new avenues for research on food-dependent dreaming and non-pharmacological interventions for sleep disturbances.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice." "The study discussed was conducted on humans via an online survey and focuses on perceived effects and associations. Further experimental research is needed to confirm direct causal links between specific foods and dream content." "Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications." "This channel is not monetized and does not provide medical advice
FoodAndDreams #NightmareResearch #LactoseIntolerance #SleepHealth #DietAndSleep
Nielsen T, Radke J, Picard-Deland C and Powell RA (2025) More dreams of the rarebit fiend: food sensitivity and dietary correlates of sleep and dreaming. Front. Psychol. 16:1544475. doi: 10.3389/fpsyg.2025.1544475
Alchepharma,Ralph Turchiano,food sensitivity dreams,dietary correlates sleep,dreaming nightmares,lactose intolerance nightmares,food allergy dreams,gluten intolerance dreams,night eating dreams,evening eating sleep,gastrointestinal symptoms dreams,diet sleep quality,food-dependent dreaming,healthy eating dreams,unhealthy eating nightmares,psychological effects food,sleep disturbances diet,specific food effects dreams,dream recall diet
A recent randomized, placebo-controlled, crossover trial investigated the link between high-dose oral thiamine supplementation and chronic fatigue in 40 patients with quiescent inflammatory bowel disease (qIBD). The study found that while high-dose thiamine (600-1800 mg/day for 4 weeks) significantly reduced fatigue, it did not alter the overall gut microbiota composition or short-chain fatty acid (SCFA) concentrations.
Instead, the study revealed a significant correlation: patients with higher baseline levels of the gut bacteria Faecalibacterium prausnitzii and Roseburia hominis were more likely to respond positively to thiamine treatment. Specifically, Faecalibacterium prausnitzii was more abundant in thiamine responders both before (P=.019) and after (P=.038) treatment. The relative abundance of both Faecalibacterium prausnitzii and Roseburia hominis inversely correlated with improvements in IBD fatigue scores. Of the patients classified as responders (those who decreased their IBD-FQ1 score by 3 or more points), all 17 individuals showed this positive response. Furthermore, Faecalibacterium prausnitzii abundance was significantly greater in these responders compared to nonresponders. These findings suggest that these specific bacteria may serve as markers to predict who will benefit from thiamine for IBD-related fatigue, rather than being directly modified by the thiamine itself.
- Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice." "The study discussed was conducted on a specific population (patients with quiescent inflammatory bowel disease). Further research may be needed to confirm these findings in other populations." "Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications." "This channel is not monetized and does not provide medical advice."
IBDFatigue #Thiamine #IBD #FaecalibacteriumPrausnitzii #InflammatoryBowelDisease
Thiamine-Reduced Fatigue in Quiescent Inflammatory Bowel Disease Is Linked to Faecalibacterium prausnitzii Abundance Bermúdez-Sánchez, Sandra et al. Gastro Hep Advances, Volume 4, Issue 1, 100533
Alchepharma,Ralph Turchiano,citation,Thiamine inflammatory bowel disease fatigue,quiescent IBD fatigue treatment,Faecalibacterium prausnitzii IBD,Roseburia hominis fatigue,gut microbiota IBD fatigue,vitamin B1 IBD,chronic fatigue IBD,butyrate gut bacteria,gut-brain axis IBD,microbial diversity IBD,thiamine supplementation benefits,Crohn's disease fatigue,ulcerative colitis fatigue,fatigue biomarkers IBD,gut health IBD,Faecalibacterium prausnitzii abundance
Vitamin A5 is a fascinating "new" vitamin that acts as a vital key in your body. It helps activate something called the Retinoid X Receptor (RXR), which is like a central control panel or "master switch" for many important functions. This crucial vitamin comes from certain foods, especially leafy green vegetables. Research suggests that many people in Western countries aren't consuming enough of these foods, leading to a potential Vitamin A5 deficiency. This lack could be a contributing factor to the rising rates of poor mental health and neurological issues. By making sure you get enough Vitamin A5 through your diet, you're essentially providing your body with the right tool to keep these vital systems running smoothly, offering a plausible explanation for why a diet rich in vegetables is so protective against many common diseases.
Disclaimers
"This video shares information for learning only and isn't medical advice." "The science on Vitamin A5 is still growing, and we need more studies in people to fully understand all its effects, especially on the brain."
"Always talk to your doctor or a health expert before changing your diet or taking any new supplements, especially if you have health concerns or take medications." "This channel does not make money from videos and does not give medical advice."
VitaminA5 #BrainHealth #HealthyEating #MentalWellness #EatYourGreens
Bohn T, Rohn S, Böhm V, Despotovic M, de Lera AR, Krezel W, Kucuk O, Bánáti D, Rühl R. Vitamin A5: Evidence, Definitions, Gaps, and Future Directions. Nutrients. 2025; 17(14):2317. https://doi.org/10.3390/nu17142317
Alchepharma,Ralph Turchiano,citation,research,study,Vitamin A5 benefits,new vitamin discovery,leafy greens brain,healthy diet mental health,RXR activation,retinoid X receptor,neurodegenerative disease prevention,cognitive function diet,what is Vitamin A5,natural brain boost,dietary supplements science,mental clarity food,immune system vitamin,cellular differentiation,chronic disease diet,carotenoids health,future of vitamins,9-cis-beta-carotene
A randomized, double-blind, placebo-controlled trial investigated the sleep-promoting effects of Heukharang lettuce (Lactuca sativa L.) extract in Korean adults aged 30-65 with poor sleep quality (Pittsburgh Sleep Quality Index (PSQI) score > 5). Over four weeks, participants received two capsules daily of either the test extract or a placebo. The study found that the test group showed a greater improvement in global PSQI scores compared to the placebo group (6.48 ± 0.63 vs. 7.41 ± 0.57, p=0.0462). Objective measurements from actigraphy revealed significant improvements in total sleep time (TST) (421.68 ± 13.29 min vs. 386.57 ± 12.27 min, p=0.0023) and sleep efficiency (SE) (83.90 ± 1.60% vs. 81.01 ± 1.50%, p=0.0342) in the test group. Polysomnography (PSG) results also favored the test group, demonstrating higher TST (358.90 ± 19.75 min vs. 322.11 ± 17.66 min, p=0.0457), higher SE (86.86 ± 3.31% vs. 79.60 ± 2.99%, p=0.0182), and lower wake after sleep onset (WASO) (39.26 ± 10.57 min vs. 68.15 ± 9.60 min, p=0.0042). These findings suggest that Heukharang extract can enhance both sleep quality and quantity and is considered safe, indicating its potential as a functional food for improving sleep.
- Disclaimers:
•This information is for educational purposes only and should not be interpreted as medical advice.
•The study discussed was conducted on Korean adults aged 30-65 with poor sleep quality. Further research may be needed to confirm these findings in other populations.
•Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.
•This channel is not monetized and does not provide medical advice.
•(Remember to include a verbal disclaimer in the video itself.)
LettuceSleep #HeukharangExtract #SleepQualityImprovement #SleepResearch #FunctionalFood
Son K, Lee M, Bok MK, Hwang KJ, Lim H. Sleep Promoting Effects of Lettuce (Lactuca sativa L.) Extracts in Korean Adults with Poor Sleep Quality: A Randomized, Double-Blind Placebo-Controlled Trial. Nutrients. 2025; 17(13):2172. https://doi.org/10.3390/nu17132172
Alchepharma,Ralph Turchiano,citation,research,study,Pittsburgh Sleep Quality Index (PSQI),total sleep time (TST),sleep efficiency (SE),wake after sleep onset (WASO),Heukharang extract efficacy,sleep disorder natural remedies,sesquiterpene lactones (BSLs),lactucin sleep,lactucopicrin sleep,GABA receptors sleep,subjective sleep quality assessment,objective sleep measures,Korean adults health,sleep duration improvement,non-pharmacological sleep aids
A recent study published in LabMed Discovery investigated the effectiveness of a vitamin D3-loaded nanoemulsion in improving core manifestations of autism spectrum disorder (ASD) in children, compared to a widely available vitamin D3 product. The research involved 80 children with ASD, aged 3 to 6 years, divided into two groups over six months. Group I received an oral vitamin D3-loaded nanoemulsion, while Group II received a marketed oral vitamin D3 product.
Results showed that supplementation with the vitamin D3-loaded nanoemulsion in Group I led to significant elevations in both 25(OH) and 1,25(OH)2 forms of vitamin D3 (P < 0.0001). This group also experienced behavioral improvements, including a reduction in ASD severity (P = 0.0002), an increase in social IQ (P = 0.04), and a rise in total language age (P = 0.0009). In contrast, Group II, receiving the marketed vitamin D3 product, did not show significant adaptive behavioral improvements, despite elevated vitamin D3 levels. The study concludes that the vitamin D3-loaded nanoemulsion offered superior bioavailability and a tangible positive influence on ASD severity, adaptive behavior, fine motor abilities, and language performance.
- Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on human participants (children with ASD). While promising, further research may be needed to confirm these findings across broader populations."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
AutismResearch #VitaminD3Nanoemulsion #ASDTreatment #Neurodevelopment #ChildhoodAutism
Study Citation:
Meguid, N. A., et al. (2025). Improved core manifestations of autism following supplementation with vitamin D3-loaded nanoemulsion. LabMed Discovery. doi.org/10.1016/j.lmd.2025.100071.
Alchepharma,Ralph Turchiano,Autism spectrum disorder,vitamin D3 nanoemulsion,core manifestations autism,language performance autism,social IQ autism,adaptive behavior ASD,vitamin D bioavailability,ASD intervention,childhood autism rating scale,Vineland adaptive behavior scale,preschool language scale,25-hydroxycholecalciferol,25-dihydroxycholecalciferol,vitamin D deficiency autism,clinical trial vitamin D,cognitive function autism,motor skills autism
A recent systematic review in the journal Nutrients analyzed 146 studies to evaluate the safety and efficacy of glucosamine and chondroitin in humans. Researchers found that for conditions like osteoarthritis and joint pain, the supplements are generally effective and well-tolerated. Over 90% of the efficacy studies included in the review reported positive outcomes for patients. Similarly, a majority of safety studies (80 out of 107) concluded that the supplements have minimal to no adverse effects, with the most common being mild gastrointestinal complaints. The most frequently studied and effective daily dosages were 1500 mg for glucosamine and 1200 mg for chondroitin, typically taken together in two or three divided doses.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The information presented is from a systematic review of 146 human studies, the majority of which were randomized controlled trials."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
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Glucosamine #Chondroitin #Osteoarthritis #JointPain #SystematicReview
Baden KER, Hoeksema SL, Gibson N, Gadi DN, Craig E, Draime JA, Tubb SM, Chen AMH. The Safety and Efficacy of Glucosamine and/or Chondroitin in Humans: A Systematic Review. Nutrients. 2025; 17(13):2093. https://doi.org/10.3390/nu17132093
Glucosamine, Chondroitin, Glucosamine Chondroitin, Osteoarthritis, Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis, Temporomandibular Disorder, Cartilage, Joint Health, Supplement Efficacy, Supplement Safety, WOMAC score, Lequesne Index, Visual Analog Scale, Joint Pain Relief, Anti-inflammatory supplements, Systematic Review, Human Studies, Clinical Trial, Glucosamine d
A recent 6-month study looked at whether taking hawthorn fruit (HF) supplements could improve facial skin and a biological marker of aging called telomere length. They had 36 adults, aged 25 to 75, participate, with some taking a hawthorn fruit powder supplement (900 mg/day) and others taking a dummy pill (placebo). The exciting news is that the group taking hawthorn fruit saw a significant boost in their skin's hydration (how moist and plump it was) compared to the placebo group. Specifically, the hawthorn group's hydration scores went up by 1.71 points on average, while the placebo group's went down by 3.00 points. While there wasn't a big change in overall telomere length, the study found that the improvements in skin hydration were particularly noticeable in people with a specific genetic makeup (those with the "CC" genotype of rs7705526). What's more, the hawthorn group also saw a reduction in wrinkles, while the control group's wrinkles actually increased, especially for those with another specific genetic makeup (the "AA" genotype of rs2853669). These results suggest that adding hawthorn fruit to your routine might help fight skin aging, and it might even work better for some people depending on their genes.
Disclaimers:
"This information is just for learning and shouldn't be taken as medical advice."
"This study was done on adults. More research might be needed to see if these results apply to everyone or if different amounts of hawthorn fruit would have the same effect."
"Always talk to a doctor or healthcare professional before changing your diet, taking new supplements, or changing any treatment plans, especially if you have health issues or are on medication."
"This channel isn't monetized, and we don't give medical advice." (Remember to say these disclaimers in your video.)
Hashtags:
HawthornForSkin #YouthfulSkin #NaturalBeauty #SkinScience #HealthyAging
Kim M, Baik I. Effects of Hawthorn Fruit Supplementation on Facial Skin Phenotypes and Leukocyte Telomere Length Stratified by TERT Polymorphisms. Nutrients. 2025; 17(12):1983. https://doi.org/10.3390/nu17121983
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Alchepharma,Ralph Turchiano,citation,research,study,Hawthorn skin benefits,younger looking skin,natural wrinkle reduction,anti-aging supplements,hawthorn fruit extract skin,healthy skin diet,genetic factors skin aging,telomeres and skin,what helps wrinkles,best supplements for skin,clear skin tips,natural remedies for dry skin,hawthorn berries benefits,skin health research,how to get glowing skin,research on natural anti-aging,improve skin elasticity
The Liver & Weight Connection: New Curcumin Research Ep. 1246 JUN 2025
Summary
A 12-month, double-blind, placebo-controlled trial has revealed that daily supplementation with 1500 mg of curcumin offers significant benefits for both liver health and weight management in individuals with Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The study demonstrated remarkable improvements in liver health markers for the curcumin group compared to the placebo group. Specifically, after 12 months, participants taking curcumin had significantly lower liver stiffness (4.2 kPa vs 6.9 kPa) and significantly less liver fat, as measured by the Controlled Attenuation Parameter (223 dB/m vs 292 dB/m). Fatty liver-associated indicators such as the Fatty Liver Index (FLI) and Hepatic Steatosis Index (HSI) also showed significant reductions.
In addition to these direct liver benefits, the curcumin group also experienced significant improvements in body composition. Body Mass Index (BMI) was significantly reduced from the 6-month mark onward. At the end of the study, the median BMI for the curcumin group was 25.97 kg/m², notably lower than the placebo group's 27.70 kg/m². Furthermore, significant decreases in total body fat and waist circumference were observed. The researchers suggest that curcumin's anti-inflammatory and antioxidant properties may underlie these combined benefits, making it a promising adjunctive therapy for managing both liver health and weight.
Disclaimers
This information is for educational purposes only and should not be interpreted as medical advice.
The study discussed was conducted on humans with Type 2 Diabetes and MASLD. Further research may be needed to confirm these findings in other populations.
Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.
This channel does not provide medical advice.
Curcumin #LiverHealth #WeightLoss #MASLD #BMI
Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Curcumin for Inflammation Control in Individuals with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Controlled Trial. Nutrients. 2025; 17(12):1972. https://doi.org/10.3390/nu17121972
Alchepharma,Ralph Turchiano,citation,research,study,Curcumin liver health,Curcumin weight loss,MASLD treatment,hepatic steatosis curcumin,curcumin liver stiffness,curcumin BMI reduction,fatty liver index,FibroScan curcumin,supplements for liver fat,curcumin body fat,clinical trial curcumin liver,antioxidant supplements liver,non-alcoholic fatty liver disease,weight management supplements,liver enzyme improvement,curcumin for metabolic syndrome
This video explores the significant potential of bergamot, particularly its Bergamot Polyphenolic Fraction (BPF), in managing cholesterol levels, based on a review in Nutrients. Bergamot primarily lowers cholesterol by inhibiting HMG-CoA reductase, the same enzyme targeted by statins, with compounds like brutieridin and melitidin playing a key role ; in vitro studies have shown up to a 30-40% reduction in cholesterol synthesis in liver cells. Clinical trials demonstrate notable LDL-C reductions, for example, 500 mg/day of BPF decreased LDL-C by 24.1% in 30 days , while 1000 mg/day lowered LDL-C by 40.8%. Doses up to 1300 mg/day have resulted in LDL-C reductions of 37.7% over 120 days in patients with metabolic syndrome.
Regarding safety, bergamot has generally been well-tolerated in human trials lasting up to 120 days, with no significant adverse effects reported. Animal studies also indicate a good safety profile, with doses up to 150 mg/kg/day of BPF showing no liver, kidney, or blood toxicity. Even in statin-intolerant patients, 1500 mg/day of bergamot extract showed favorable results without adverse effects in one study. However, it's important to note that data on long-term safety and use at higher doses are still limited. Caution is advised for individuals on multiple medications due to the potential for drug-nutraceutical interactions, which are not yet fully understood.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The review discusses findings from preclinical studies and clinical trials. While short-term human studies (up to 120 days) suggest bergamot is generally well-tolerated , comprehensive long-term safety data, especially at higher doses, is still emerging. The effects of bergamot can vary based on the individual, the formulation, and dosage."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, particularly if you have a medical condition, are taking medications (especially for cholesterol or other cardiovascular issues), or are considering bergamot supplementation. Discuss potential interactions if you are on polypharmacy."
"This channel does not provide medical advice."
BergamotCholesterol #NutraceuticalSafety #LipidManagement #HeartHealthSupplements #Bergamot
Carpenito M, Coletti F, Muscoli S, Guarino L, Di Cristo A, Cammalleri V, Mega S, Emerenziani S, Cicala M, Fanali C, et al. Unveiling the Power of Bergamot: Beyond Lipid-Lowering Effects. Nutrients. 2025; 17(11):1871. https://doi.org/10.3390/nu17111871
Alchepharma,Ralph Turchiano,Bergamot cholesterol reduction,bergamot safety profile,bergamot side effects,bergamot HMG-CoA reductase,bergamot triglycerides,bergamot clinical trials cholesterol,safe cholesterol supplements,natural cholesterol lowering,bergamot long-term use,bergamot dosage for cholesterol,bergamot vascular benefits,bergamot antioxidant heart,bergamot and statins,small dense LDL reduction,dyslipidemia nutraceuticals,bergamot mechanisms of action
Vitamin D Slows Biological Aging? New 4-Year Study on Telomeres! Ep. 1244 JUN 2025
A recent sub-study of the large-scale VITamin D and OmegA-3 TriaL (VITAL), published in The American Journal of Clinical Nutrition, has revealed significant findings regarding vitamin D and cellular aging. Researchers analyzed leukocyte telomere length (LTL) in 1,054 participants over four years. The results showed that daily supplementation with 2,000 IU of vitamin D3 significantly reduced telomere shortening compared to a placebo. Specifically, vitamin D3 supplementation decreased LTL attrition by 0.14 kilobase pairs over the four years (p=0.039), an effect described as equivalent to preventing nearly three years of biological aging. This is the first large-scale, long-term randomized trial to show this protective effect on telomeres, which are caps at the ends of chromosomes linked to aging. Interestingly, marine omega-3 fatty acid supplementation did not show a significant effect on telomere length in this sub-study. These findings add to previous VITAL results showing vitamin D's role in reducing inflammation and risks of certain age-related diseases.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on U.S. females aged 55 years and older and males aged 50 years and older. Findings may not apply to other populations."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications. Do not exceed recommended dosages of Vitamin D without medical supervision."
"This channel does not provide medical advice."
VitaminD #Telomeres #AntiAgingResearch #VITALStudy #CellularHealth
Haidong Zhu, JoAnn E. Manson, Nancy R. Cook, Bayu B. Bekele, Li Chen, Kevin J. Kane, Ying Huang, Wenjun Li, William Christen, I-Min Lee, Yanbin Dong. Vitamin D3 and Marine Omega-3 Fatty Acids Supplementation and Leukocyte Telomere Length: 4-Year Findings from the VITAL Randomized Controlled Trial. The American Journal of Clinical Nutrition, 2025; DOI: 10.1016/j.ajcnut.2025.05.003
Alchepharma,Ralph Turchiano,citation,research,study,Vitamin D3 supplementation,leukocyte telomere length,LTL attrition,VITAL trial,biological aging,cellular aging,chromosome protection,anti-aging supplements,vitamin D benefits,telomere shortening reduction,2000 IU vitamin D,chronic disease prevention,inflammation reduction,advanced cancer risk,autoimmune disease risk,Mass General Brigham,genetic aging markers,DNA protection,long-term vitamin D effects
A recent randomized, double-blind, crossover trial published in Nutrients investigated the effects of short-term beetroot juice (BJ) supplementation on resistance-trained males. Eleven healthy men (average age 21.3±1.9 years) consumed either beetroot juice, providing 450 mg of nitrate per day, or a nitrate-free placebo. The study found that BJ supplementation significantly enhanced high-intensity resistance performance. Specifically, participants completed more repetitions at 80% of their one-repetition maximum (1RM) in both bench press and back squat exercises when taking beetroot juice compared to the placebo. Peak movement velocity also improved across all tested intensities (60-80% 1RM) with BJ supplementation. Furthermore, beetroot juice led to higher muscle oxygenation (SmO2 ) particularly at 70-80% 1RM and this effect was even more pronounced after 72 hours of supplementation. The study also noted reduced cardiovascular strain, evidenced by lower peak heart rates during exercise with BJ. Post-exercise recovery favored beetroot juice, with participants showing faster recovery in jump performance (both countermovement and squat jumps) at 24 hours and experiencing reduced upper-limb delayed-onset muscle soreness (DOMS) at 24-48 hours. These findings suggest that short-term BJ supplementation can be a practical strategy for physically active individuals looking to optimize training performance and accelerate recovery.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on healthy, physically active young men. Further research may be needed to confirm these findings in other populations, including women, older adults, or individuals with medical conditions."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
BeetrootJuice #NitrateSupplementation #ResistanceTraining #ExercisePerformance #MuscleRecovery
Salem A, Ammar A, Kerkeni M, Boujelbane MA, Uyar AM, Köbel LM, Selvaraj S, Zare R, Heinrich KM, Jahrami H, et al. Short-Term Beetroot Juice Supplementation Enhances Strength, Reduces Fatigue, and Promotes Recovery in Physically Active Individuals: A Randomized, Double-Blind, Crossover Trial. Nutrients. 2025; 17(10):1720. https://doi.org/10.3390/nu17101720
A recent study in mice explored how a combination of two supplements, lactoferrin and creatine, might help with age-related muscle loss, a condition called sarcopenia. Scientists induced sarcopenia in mice, causing their muscle mass and function to decline. For 8 weeks, these mice were given lactoferrin, creatine, or a mixture of both. The results were promising: the group of mice receiving both lactoferrin and creatine showed the most significant improvements. For example, the lean body content in the sarcopenia model group dropped to around 47-48%, while the group receiving the combination treatment saw their lean body content increase to about 51-52%, bringing them above the levels of the healthy control group (around 50%). In terms of muscle function, the combination group's endurance on a treadmill test was approximately 1200 seconds, a significant improvement compared to the sarcopenia model group (around 600 seconds) and even surpassing the healthy control group (around 900 seconds). Their grip strength also increased to roughly 180g with the combination, compared to about 130g in the model group and 150g in controls. These findings suggest that combining lactoferrin and creatine could be a beneficial nutritional strategy to combat muscle decay associated with aging, potentially by improving how muscles use energy and build protein.
- Disclaimers:
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed was conducted on mice. Further research is needed to confirm these findings in humans."
•"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
•"This Channel does not provide medical advice."
Sarcopenia #MuscleHealth #Lactoferrin #Creatine #AgingWell
Wu W, Guo X, Qu T, Huang Y, Tao J, He J, Wang X, Luo J, An P, Zhu Y, et al. The Combination of Lactoferrin and Creatine Ameliorates Muscle Decay in a Sarcopenia Murine Model. Nutrients. 2024; 16(12):1958. https://doi.org/10.3390/nu16121958
Sarcopenia, creatine, lactoferrin, muscle mass, muscle function, aging, muscle decay, D-galactose, C57BL/6 mice, muscle strength, endurance, grip strength, lean body mass, nutritional intervention, muscle protein synthesis, energy metabolism, myogenic factors, RNA-seq, mTOR signaling, PI3K-Akt signaling, longevity regulating pathway, muscle atrophy, animal model, skeletal muscle, nutritional supplements
Monk Fruit Extract: Zero-Calorie Sweetener, Surprising Benefits? Ep. 1241 MAY 2025
A recent PRISMA-guided systematic review published in Nutrients synthesized findings from randomized controlled trials (RCTs) to assess the impact of monk fruit extract (MFE) on metabolic health, lipid profiles, inflammation, and regulatory considerations. The review included a number of RCTs (note: while some search results indicated 10, others mentioned 5 included studies; refer to the final published article for the definitive number). The findings indicate that MFE may help reduce postprandial glucose levels (by 10–18% in included studies) and insulin responses (by 12–22%). Some studies also reported reductions in inflammatory markers such as IL-6 and TNF-α. No severe adverse effects were observed in the reviewed trials. The review also notes that MFE is approved for use in the United States and China, with its status under review in the European Union. The authors suggest MFE shows potential as a functional food ingredient for metabolic health, though they highlight the need for long-term clinical trials and a harmonized regulatory framework to confirm its long-term safety and efficacy within sustainable health strategies.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"This video discusses a systematic review of randomized controlled trials. While this represents a high level of evidence, individual results may vary, and further research is always ongoing."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
MonkFruitExtract #MetabolicHealth #SystematicReview #RandomizedControlledTrials #SustainableHealth
Kaim U, Labus K. Monk Fruit Extract and Sustainable Health: A PRISMA-Guided Systematic Review of Randomized Controlled Trials. Nutrients. 2025; 17(9):1433. https://doi.org/10.3390/nu17091433
Alchepharma,Ralph Turchiano,citation,research,study,Monk fruit extract,Siraitia grosvenorii,mogrosides,metabolic health,glycemic control,insulin response,inflammation,blood glucose,type 2 diabetes,natural sweeteners,low-calorie sweeteners,functional foods,dietary supplements,clinical trials,systematic review,PRISMA,nutritional science,dietary interventions,sugar substitutes,glucose metabolism,insulin sensitivity,inflammatory markers,regulatory status
Unlock the science behind Ashwagandha and stress! A pivotal 2023 systematic review published in Nutrients meticulously analyzed the current evidence on Withania somnifera's effect on the primary stress hormone, cortisol. By synthesizing data from nine clinical studies involving stressed human subjects, researchers investigated Ashwagandha's potential to modulate the hypothalamic-pituitary-adrenal (HPA) axis. The compelling finding? Supplementation with Ashwagandha for periods ranging from 30 to 112 days was consistently associated with significant reductions in cortisol levels, ranging from 11% to as much as 32.6%, compared to placebo groups. This review strongly suggests that short-term Ashwagandha use holds promise for buffering the physiological stress response in humans. However, the authors caution that dosages and formulations varied, and the long-term effects on adrenal function require further investigation.
- Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"This video discusses findings from a systematic review of studies conducted on stressed human subjects over short durations (30-112 days). Individual results can vary significantly based on dosage, formulation, duration of use, and individual health status. Long-term effects are not well established."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition (like thyroid disorders, autoimmune diseases, or hormone-sensitive conditions), are pregnant or breastfeeding, or are taking medications (such as immunosuppressants, sedatives, thyroid hormone, or medications for diabetes or high blood pressure)."
"This channel does not provide medical advice."
Ashwagandha #Cortisol #StressResponse #SystematicReview #Adaptogens
Della Porta M, Maier JA, Cazzola R. Effects of Withania somnifera on Cortisol Levels in Stressed Human Subjects: A Systematic Review. Nutrients. 2023; 15(24):5015.
A 2024 randomized controlled trial published in the journal Nutrients investigated curcumin's effects on obese patients managing both type 2 diabetes and depression. The primary finding was a highly significant improvement in depression scores (measured by PHQ-9) for the group receiving curcumin compared to the placebo group over 12 months.
Importantly, the positive benefits extended substantially beyond mood improvement. The study revealed several other markedly positive secondary outcomes in the curcumin group:
Neurotransmitter Support: Significantly higher levels of serotonin (often linked to mood regulation).
Reduced Inflammation: Significantly lower levels of key pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α).
Enhanced Antioxidant Defense: Significantly increased total antioxidant status and activity of crucial antioxidant enzymes (glutathione peroxidase, superoxide dismutase).
Lowered Oxidative Stress: Significantly lower levels of malondialdehyde, a marker of lipid peroxidation and oxidative damage.
These impressive and wide-ranging results, demonstrating statistically significant positive effects across depression symptoms, neurotransmitter levels, inflammation, and oxidative stress pathways, suggest that curcumin supplementation shows considerable potential as a beneficial complementary strategy for this specific patient population dealing with the complex interplay of obesity, type 2 diabetes, and depression.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on a specific population: obese adults with type 2 diabetes. These findings may not be generalizable to other populations or individuals with different health conditions."
"Curcumin supplements can interact with various medications (like blood thinners or diabetes medications which might increase the risk of low blood sugar) and may not be appropriate for everyone. Always consult with a qualified healthcare professional before starting or stopping any supplement, including curcumin, or making changes to your treatment plan, especially if you have diabetes, depression, or any other medical condition."
"This channel is not monetized and does not provide medical advice."
Curcumin #Depression #Type2Diabetes #Obesity #mood
Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Curcumin Reduces Depression in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial. Nutrients. 2024; 16(15):2414. https://doi.org/10.3390/nu16152414
Alchepharma,Ralph Turchiano,research,Curcumin,depression,type 2 diabetes,T2DM,obesity,metabolic syndrome,inflammation,oxidative stress,mental health,mood disorders,complementary therapy,turmeric,human study,obese patients,diabetic complications,glycemic control,insulin resistance,neuroinflammation,serotonin,interleukin,IL-6,TNF-alpha,dietary supplement,mental well-being,comorbid mood symptoms,diabetes management,alternative treatments,PHQ-9,biomarkers
A recent 12-week randomised controlled trial involving healthy adults aged 55-70 yielded significant positive findings regarding pomegranate extract's effect on blood pressure. While the study might not have shown significant differences compared to placebo across all initially measured markers, it revealed important reductions within the group taking pomegranate extract daily. Specifically, participants supplementing with pomegranate extract saw a statistically significant average decrease in Systolic Blood Pressure (SBP) by 5.22 mmHg and Diastolic Blood Pressure (DBP) by 3.6 mmHg. The researchers highlight the potential clinical relevance of the SBP reduction, noting that a 5 mmHg drop is associated with an estimated 10% decrease in the risk of major cardiovascular events. These findings align with previous research and meta-analyses confirming pomegranate's blood pressure-lowering effects, suggesting pomegranate extract could be a supportive strategy for hypertension prevention in older adults.
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was a randomised controlled trial in healthy adults aged 55-70."
"The significant positive findings highlighted are the reductions in Systolic and Diastolic blood pressure observed within the group taking pomegranate extract. The authors note the SBP reduction is potentially clinically relevant."
"These blood pressure findings are consistent with other studies and meta-analyses on pomegranate, strengthening the evidence for this specific effect."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially regarding blood pressure management or if you have existing health conditions or take medications."
"This channel is not monetized and does not provide medical advice."
PomegranateExtract, #BloodPressure, #SystolicBloodPressure, #ClinicalRelevance, #HypertensionPrevention
Farhat G, Malla J, Vadher J, Al-Dujaili EAS. Effects of Pomegranate Extract on Inflammatory Markers and Cardiometabolic Risk Factors in Adults Aged 55–70 Years: A Randomised Controlled Parallel Trial. Nutrients. 2025; 17(7):1235.
This video explores a comprehensive review published in the journal Nutrients focusing on Astragalus membranaceus and its potential role in delaying aging. What's fascinating is the breadth of mechanisms discussed: the review highlights how active phytochemicals in Astragalus root – like specific polysaccharides, flavonoids, and saponins – exert powerful antioxidant, anti-inflammatory, and immune-regulating effects. These properties are linked to protecting cells from damage and dysfunction associated with aging. The review specifically points to benefits for skin health, suggesting these compounds may help maintain skin condition and prevent tissue degeneration. Beyond the skin, the research surveyed indicates potential protective effects across multiple body systems – including the cardiovascular, nervous, and immune systems – painting a picture of Astragalus as a multifaceted agent in promoting healthspan and potentially slowing the aging process at a cellular level.
Disclaimers:
"This information is based on a scientific review article summarizing existing research and is for educational purposes only. It is not medical advice."
"This review covers a range of studies (potentially including human, animal, and cell-based research). Consult the original review article for details on the sources of evidence. Further research is often needed."
"Always consult a qualified healthcare professional before using Astragalus supplements or making changes to your health plan. Astragalus can interact with medications and may not be suitable for everyone, especially those with certain medical conditions."
"This channel is not monetized and does not provide medical advice."
AstragalusMembranaceus #CellularAging #SkinAging #Astragalus #Phytochemicals
Borowicz KK, Jach ME. Astragalus Membranaceus—Can It Delay Cellular Aging? Nutrients. 2025; 17(8):1299. https://doi.org/10.3390/nu17081299
Astragalus membranaceus,cellular aging,review,anti-aging,traditional Chinese medicine,antioxidants,flavonoids,saponins,polysaccharides,immunomodulation,inflammation,skin health,longevity,phytotherapy,herbal remedies,natural supplements,oxidative stress,senescence,gerontology,nutrients journal,adaptogen,cardiovascular health,immune support,regenerative medicine,systemic effects
This research overview explores nutritional approaches to combat muscle loss, also known as sarcopenia, a common age-related issue. The study emphasizes the critical role of diet in maintaining muscle health and strength. Key nutrients like protein, vitamin D, leucine, creatine, and HMB are discussed regarding their impact on muscle protein synthesis, directly affecting the progression of sarcopenia. The review highlights that personalized dietary strategies, tailored to individual needs, combined with exercise, are essential for effectively addressing muscle loss, mitigating sarcopenia, and improving overall physical functionDisclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The information reviewed is based on research studies, and individual results may vary."
"Always consult with a qualified healthcare professional or registered dietitian before making any changes to your diet or1 treatment plan, especially if you have a medical condition or are taking medications."
MuscleLoss #Sarcopenia #Nutrition #Protein #VitaminD
Muscle loss, sarcopenia, muscle atrophy, aging, nutrition, protein intake, vitamin D, leucine, creatine, HMB, muscle health, elderly nutrition, dietary interventions, muscle strength, physical function, geriatric nutrition, muscle protein synthesis, sarcopenia treatment, muscle loss treatment, nutritional management, muscle mass, healthy aging, diet for muscle loss, muscle wasting, geriatric care, nutritional supplements
Barone M, Baccaro P, Molfino A. An Overview of Sarcopenia: Focusing on Nutritional Treatment Approaches. Nutrients. 2025; 17(7):1237. https://doi.org/10.3390/nu17071237
A recent review published in Nutrients explored the potential benefits of magnesium supplementation for migraine management. The research analyzed existing studies and found that magnesium may play a significant role in alleviating migraine symptoms. Specifically, the review indicates that magnesium can influence neurological pathways involved in migraine attacks, potentially reducing their frequency and severity. The review points to magnesium's ability to modulate neurotransmitter function and decrease neuronal excitability. The findings suggest that magnesium supplementation could be a valuable tool for individuals seeking natural migraine relief. While the review highlights promising benefits, further clinical trials are necessary to solidify these results and optimize magnesium dosage for migraine sufferers
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"This study is a review of existing literature, and further research, including clinical trials, is needed to confirm these findings."
"Always consult with a qualified healthcare professional before starting any new supplement regimen, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
MagnesiumMigraineRelief #MagnesiumBenefits #NaturalMigraineSupport #MigraineSupplement #MagnesiumForHeadaches
Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025; 17(4):725. https://doi.org/10.3390/nu17040725
This research explored the potential of Keyfobell Powder (KFB), a novel extract, to mimic the longitudinal bone growth effects of somatropin (human growth hormone) through the upregulation of IGF-1. KFB is composed of a mixture of Astragalus membranaceus water extract, red ginseng (Panax ginseng C.A. Meyer) 30% ethanolic extract, and Cervi Parvum Cornu 50% ethanolic extract, mixed in a ratio of 1:1.1:7.4. The study found that KFB supplementation significantly increased IGF-1 levels, leading to enhanced bone elongation in animal models. This suggests KFB may offer a natural alternative to somatropin, potentially with a reduced risk of side effects. While somatropin is effective for growth promotion, it can be associated with adverse effects. This study proposes that KFB, through its combination of Astragalus, red ginseng, and deer antler extract, could provide similar benefits by naturally stimulating IGF-1 production, thus promoting bone growth. It's crucial to acknowledge that this research was conducted on animal models, and human clinical trials are necessary to confirm these findings and assess the safety and efficacy of KFB as a somatropin alternative
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on animal models. Further research is needed to confirm these findings in humans."
"Always consult with a qualified healthcare professional before considering any growth hormone or growth-promoting alternatives, especially if you have a medical condition or are taking medications."
SomatropinAlternative #KeyfobellPowder #IGF1 #BoneGrowth #NaturalGrowth
YouTube Channel ID: UCSxq36i1g2yb-GdmNq77U7w
Lee MJ, Jeong D, Lee JH, Kang J, Choi J, Seo J, Kim HI, Seo J, Ko K, Nam DH, et al. The Effects of a Novel Astragalus-Based Extract (Keyfobell Powder (KFB)) on Longitudinal Bone Growth via IGF-1 Upregulation: A Potential Growth Hormone Alternative. Nutrients. 2025; 17(3):416. https://doi.org/10.3390/nu17030416
Alchepharma,Ralph Turchiano,citation,research,study,Somatropin,growth hormone,Astragalus membranaceus,Panax ginseng,Cervi Parvum Cornu,Keyfobell Powder,longitudinal bone growth,growth hormone alternative,natural growth hormone,bone elongation,skeletal growth,pediatric growth,growth disorders,growth hormone deficiency,clinical trials,bone density,cartilage growth,growth promotion,somatropin side effects,IGF-1 upregulation,phytotherapy,natural bone growth
4X Thicker Hair? Gynostemma pentaphyllum Clinical Trial Results Ep. 1233 MAR 2025
A recent randomized, double-blind, placebo-controlled clinical trial published in Nutrients (2025) investigated the therapeutic potential of Gynostemma pentaphyllum extract for enhancing hair health. The study involved participants experiencing hair thinning. After 24 weeks, the Gynostemma pentaphyllum group showed a threefold increase in hair elasticity and density and a fourfold increase in hair diameter compared to the placebo group. Additionally, participants reported better outcomes in terms of reducing hair damage and dryness. These findings suggest that Gynostemma pentaphyllum extract may offer a natural and effective approach to promoting hair health.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on a specific population experiencing hair thinning. Further research may be needed to confirm these findings in broader populations and to understand the long-term effects."
"Always consult with a qualified healthcare professional before starting any new supplement or treatment regimen, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
Channel ID: UCSxq36i1g2yb-GdmNq77U7w
GynostemmaPentaphyllum #HairHealth #HairLoss #ClinicalTrial #NaturalRemedies
Lee J, Jin Y, Zhang X, Kim M, Koh A, Zhou S, Lee C, Seo M, Kim S, Jo S, et al. Therapeutic Potential of Gynostemma pentaphyllum Extract for Hair Health Enhancement: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2025; 17(5):767. https://doi.org/10.3390/nu17050767
Gynostemma pentaphyllum, jiaogulan, hair loss, hair growth, hair density, hair thickness, clinical trial, natural hair remedies, hair thinning, supplement, hair health, study results, randomized controlled trial, double-blind, placebo controlled, hair follicle count, hair shaft diameter, herbal remedies, nutrition, hair care, scalp health, androgenetic alopecia, alopecia, natural treatment, botanical extracts, nutrients, hair revitalization
This systematic review, published in Nutrients in 2025, examined the multifaceted health impacts of Yacon syrup, focusing on its role as a natural sweetener and its potential benefits for weight management and overall well-being. Yacon syrup, derived from the Yacon plant, is valued for its sweet taste and high content of fructooligosaccharides (FOS), which function as prebiotics. This review highlights several potential benefits: Yacon syrup can serve as a lower-calorie alternative to refined sugars, potentially aiding in weight management. Its FOS content promotes the growth of beneficial gut bacteria, contributing to a healthy gut microbiome. Additionally, some studies suggest potential positive impacts on glucose metabolism and lipid profiles, potentially benefiting individuals with metabolic concerns. The prebiotic effects may also contribute to improved satiety, assisting in calorie control. While these findings are promising, it’s important to remember that more robust clinical trials are needed to solidify these results and understand the long-term effects of Yacon syrup. It should be used in moderation as part of a balanced diet and healthy lifestyle.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"While Yacon syrup is a natural sweetener, it should still be consumed in moderation."
"The weight loss effects of Yacon syrup are still under investigation, and results may vary."
"Always consult with a qualified healthcare professional before making any changes to your diet or supplement regimen, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
(Remember to include a verbal disclaimer in the video.)
YaconSyrupSweetener #NaturalSweetener #WeightLossSweetener #HealthySweetener #PrebioticSweetener
Pereira MF, Soares IdC, Cabral MM, de Freitas PA, Sousa GMA, Magalhães SC, Carioca AAF, de Oliveira MRC, Magalhães FEA, de Oliveira AC, et al. Impacts of Yacon Syrup (Smallanthus sonchifolius) on Human Health: A Systematic Review of Scientific Evidence from the Last Decade. Nutrients. 2025; 17(5):888. https://doi.org/10.3390/nu17050888
Alchepharma,Ralph Turchiano,citation,research,study,Yacon syrup sweetener,natural sweeteners and weight loss,low-calorie sweeteners,prebiotic sweeteners,healthy sugar alternatives,Yacon syrup and sugar replacement,FOS sweeteners,weight management sweeteners,dietary sweeteners,sugar substitutes,blood sugar friendly sweeteners,natural sweeteners benefits,healthy dessert sweeteners,nutritional sweetening,alternative sweeteners,weight loss and sweet food
This research, a component of the larger DO-HEALTH trial, specifically examined the impact of vitamin D, omega-3 fatty acids, and exercise on DNA methylation clocks, indicators of biological aging, in a subset of approximately 777 older adults. While the broader DO-HEALTH trial included over 2,000 participants, this particular study focused on those with available DNA methylation data. The researchers found that a combined intervention of vitamin D, omega-3, and exercise led to a noticeable slowing of biological aging, as reflected in the DunedinPACE epigenetic clock. Although individual interventions also showed some positive trends, the combined approach demonstrated the most significant effect. This study highlights how targeted lifestyle interventions can potentially influence biological aging in older adults, based on analysis of a specific subset of the DO-HEALTH trial participants.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on a subset of older adults from the DO-HEALTH trial. Further research may be needed to confirm these findings in other populations."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or exercise program, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
BiologicalAging #VitaminD #Omega3 #Exercise #DNAMethylation
Bischoff-Ferrari, H.A., Gängler, S., Wieczorek, M. et al. Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial. Nat Aging (2025). https://doi.org/10.1038/s43587-024-00793-y
Biological aging, DNA methylation, vitamin D, omega-3 fatty acids, exercise, older adults, DO-HEALTH trial, aging reversal, epigenetic clock, lifestyle interventions, healthy aging, cellular aging, gerontology, longevity, aging biomarkers, clinical trial, nutritional supplements, physical activity, epigenetic modifications, methylation patterns, aging research, preventative medicine, geriatrics, anti-aging strategies, molecular biology, healthspan.
This groundbreaking study has shed light on the potential of lycopene, a powerful antioxidant found in tomatoes, to combat depression-like behavior in mice subjected to chronic social defeat stress, a model for chronic stress. Researchers found that lycopene treatment significantly alleviated these behaviors. The study's key discovery centers around synaptic plasticity, the brain's ability to modify and strengthen connections between neurons, which is often impaired by stress. The research suggests that lycopene may exert its beneficial effects by enhancing synaptic plasticity, specifically through the BDNF-TrkB signaling pathway. This pathway is essential for neuronal growth, survival, and function, and plays a critical role in mood regulation. This breakthrough discovery linking lycopene, synaptic plasticity, and stress opens new avenues for depression research and potential treatment strategies. While these pre-clinical findings in mice are promising, further human studies are necessary to validate these results and explore the therapeutic potential of lycopene for depression.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on mice. Further research, including human clinical trials, is needed to confirm these findings."
"Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
Lycopene #Depression #MentalHealth #BDNF #SynapticPlasticity #Neurobiology #PreclinicalResearch #MouseModel #ChronicSocialDefeatStress #Antioxidant #Breakthrough #StressResearch
Lycopene, depression, mental health, BDNF, synaptic plasticity, chronic social defeat stress, mouse model, antidepressant, natural remedies, carotenoid, brain health, neurobiology, TrkB pathway, mood regulation, behavioral study, preclinical research, lycopene benefits, dietary interventions, nutritional psychiatry, tomato benefits, antioxidant, brain function, neuroplasticity, synaptic strengthening, neuronal connections, animal model of depression, synaptic modulation, neurotrophic factors, stress, chronic stress, breakthrough research
Zeng, Q., Gao, J., Liu, Y., Li, X., & Luo, J. (2023). Lycopene alleviates depression-like behavior in chronic social defeat stress-induced mice by promoting synaptic plasticity via the BDNF–TrkB pathway. Food Science and Nutrition, 11(1), 585–595. https://doi.org/10.1002/fsn3.70003
Hope for Heart Failure: New Research on Tricaprin Ep. 1229 FEB 2025
This study explored the potential benefits of tricaprin, a natural supplement, for individuals with a specific, less common type of heart failure. This particular form of heart failure makes it difficult for the body to process certain fats. The research suggests that tricaprin may offer a promising approach for improving both survival rates and the overall health of the heart in these patients. The study followed a small group of patients who received tricaprin and compared their outcomes to a larger group who did not. Specifically, the study showed a 100% 3-year and 5-year survival rate for the patients receiving tricaprin, compared to 78.6% and 68.1% respectively for the control group. These results indicated that those taking tricaprin experienced significant improvements in long-term survival and heart function. While these findings are encouraging, it's important to remember that this research focused on a specific type of heart failure.
Disclaimer:
This information is for educational purposes only and should not be interpreted as medical advice.
This study looked at a specific group of patients with a rare form of heart failure. More research is needed to see if these findings apply to other types of heart failure.
Always talk to your doctor or other qualified healthcare provider before starting any new supplement or making changes to your treatment plan, especially if you have a heart condition.
This channel does not provide medical advice.
HeartFailure #Tricaprin #NaturalHealth #HeartHealth #Research
Ken-ichi Hirano et al, Long-term survival and durable recovery of heart failure in patients with triglyceride deposit cardiomyovasculopathy treated with tricaprin, Nature Cardiovascular Research (2025). DOI: 10.1038/s44161-025-00611-7
Tricaprin, heart failure, research, natural supplement, cardiac health, survival rates, clinical trial, heart condition, rare disease, potential treatment, promising results
A new study published in the journal Antioxidants investigated the effects of luteolin, a natural compound found in plants, on hair graying in mice. The researchers found that both external (topical) and internal (oral) administration of luteolin significantly reduced the number of gray hairs in the mice. The study also revealed that luteolin works by improving the signaling between cells involved in hair pigmentation, ultimately leading to a reduction in hair graying. These findings suggest that luteolin may be a promising natural treatment for hair graying in humans, although further research is needed to confirm these effects.
- Disclaimers:
This information is for educational purposes only and should not be interpreted as medical advice.
The study discussed was conducted on mice. Further research is needed to confirm these findings in humans.
Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.
This channel does not provide medical advice.
Luteolin #GrayHair #HairLoss #Antioxidants #HairScience
Luteolin, gray hair, hair loss, hair graying, antioxidants, flavonoids, hair health, hair pigmentation, melanocytes, keratinocytes, stem cells, Ednrb, RET mice, study, research findings, natural treatment, hair care, hair growth, anti-aging
This research article investigated the effects of Brussels chicory on exercise performance and recovery in untrained college students. The study found that consuming Brussels chicory juice daily for 7 days increased time to exhaustion during high-intensity exercise by 8.3% in men and 12.2% in women. This improvement in performance was observed despite no significant changes in maximal oxygen consumption (VO2 max). Additionally, Brussels chicory consumption promoted post-exercise recovery, evidenced by a reduction in blood lactate levels by 14.5% in men and 10.6% in women. The study suggests that these improvements may be due to the promotion of lactate oxidation, a process that helps clear lactate from the muscles and improve acid-base balance
Disclaimers:
This information is for educational purposes only and should not be interpreted as medical advice.
The study discussed was conducted on a specific population (untrained college students). Further research is needed to confirm these findings in other populations.
Always consult with a qualified healthcare professional before making any changes to your diet or exercise plan, especially if you have a medical condition or are taking medications.
This channel is not monetized and does not provide medical advice.
BrusselsChicory #ExercisePerformance #PostExerciseRecovery #LactateOxidation #SportsScience
Mao Y, Huang J, Li S, Chen G, Du Y, Kang M, Zhu S, Zhang W, Xu Q, Wang Y, et al. Brussels Chicory Enhances Exhaustive Aerobic Exercise Performance and Post-Exercise Recovery, Possibly Through Promotion of Lactate Oxidation: A Pilot Randomized, Single-Blind, Placebo-Controlled, Two-Way Crossover Study. Nutrients. 2025; 17(2):365. https://doi.org/10.3390/nu17020365
A fascinating new study published in the journal Nutrients explored the impact of elderberry juice on metabolic health. Researchers had participants drink elderberry juice every day for one week, and the results were pretty amazing.
They discovered that elderberry juice led to a significant 24% reduction in blood sugar levels after meals. This means the body became much better at regulating blood sugar, which is crucial for overall health and for people managing conditions like prediabetes or type 2 diabetes.
But that's not all! The study also found a 27% increase in fat oxidation, meaning the body became more efficient at burning fat for energy. This could have exciting implications for weight management and metabolic health.
While more research is needed to confirm these findings in larger populations, this study provides compelling evidence for the potential benefits of elderberry juice.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on healthy adults. Further research is needed to confirm these findings in other populations and individuals with health conditions."
"Always consult with a qualified healthcare professional before making any changes to your diet or lifestyle, especially if you have a medical condition or are taking medications."
ElderberryJuice #BloodSugar #FatBurning #Metabolism #WeightLoss
Teets C, Ghanem N, Ma G, Minj J, Perkins-Veazie P, Johnson SA, Etter AJ, Carbonero FG, Solverson PM. A One-Week Elderberry Juice Intervention Augments the Fecal Microbiota and Suggests Improvement in Glucose Tolerance and Fat Oxidation in a Randomized Controlled Trial. Nutrients. 2024; 16(20):3555. https://doi.org/10.3390/nu16203555
elderberry juice, blood sugar, glucose, insulin, fat burning, weight loss, metabolism, metabolic health, study, research, science, health benefits, healthy living, natural remedies, type 2 diabetes, prediabetes, gut health, antioxidants
A recent study published in the journal Nutrients investigated the effects of Weizmannia coagulans BC99 on strength performance and muscle quality in a group of male college students majoring in physical education. These students were likely already engaged in regular physical activity, making them a good test group for this type of supplement.
Here's what the researchers found:
Significant Improvement in Strength: Participants who took BC99 showed a marked increase in their strength performance across various exercises. This suggests that BC99 could help athletes and fitness enthusiasts achieve new levels of strength.
Enhanced Muscle Growth: The study also revealed that BC99 supplementation led to an increase in skeletal muscle mass. This finding indicates that BC99 may play a role in promoting muscle growth and development.
Improved Protein Digestion: Researchers observed that BC99 enhanced protein digestion in the participants. This is important because efficient protein digestion is crucial for muscle building and recovery.
Regulation of Muscle Quality: BC99 appeared to positively influence hormones related to muscle growth and repair, suggesting a potential role in improving overall muscle quality.
This study provides compelling evidence that Weizmannia coagulans BC99 could be a valuable supplement for those seeking to enhance their strength and muscle health. However, it's important to remember that more research is needed, especially in diverse populations.
- Disclaimers:
"The information presented in this video is intended for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications.
"The study discussed was conducted on young, healthy male college students. Further research is needed to determine if these findings apply to other populations, including women, older adults, and individuals with different health backgrounds."
"This channel is not monetized and does not endorse any specific products or brands. Any mention of supplements is for informational purposes only."
WeizmanniaCoagulans #BC99 #StrengthTraining #MuscleGrowth #SportsNutrition #Supplements #Fitness #AthleticPerformance #HealthAndWellness #ResearchUpdate
Cao L, Guo M, Zhou Y, Zhang J, Tie S, Li X, Tian P, Wu Y, Gu S. Weizmannia coagulans BC99 Improves Strength Performance by Enhancing Protein Digestion and Regulating Skeletal Muscle Quality in College Students of Physical Education Major. Nutrients. 2024; 16(23):3990. https://doi.org/10.3390/nu16233990
Weizmannia coagulans BC99, strength training, muscle growth, athletic performance, sports nutrition, supplements, probiotics, gut health, protein digestion, amino acids, muscle protein synthesis, testosterone, growth hormone, exercise physiology, clinical trial, research study, health and wellness, fitness enthusiasts, athletes, dietary supplements, nutritional strategies
A groundbreaking 2025 systematic review and meta-analysis published in Nutrients investigated the effects of maca (Lepidium meyenii) on physical performance in both animals and humans. This comprehensive review analyzed numerous studies, finding compelling evidence that maca supplementation can significantly enhance various aspects of physical performance, including endurance, strength, and speed. These findings have exciting implications for athletes and anyone seeking to optimize their physical capabilities.
Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The studies discussed in this review were conducted on both animals and humans. Further research may be needed to confirm these findings and explore optimal dosages and long-term effects."
"Always consult with a qualified healthcare professional before taking maca or any new supplement, especially if you have a medical condition or are taking medications."
Maca #Superfoods #Fitness #Workout #EnergyBoost
Huerta Ojeda Á, Rodríguez Rojas J, Cancino-López J, Barahona-Fuentes G, Pavez L, Yeomans-Cabrera M-M, Jorquera-Aguilera C. Effects of Maca (Lepidium meyenii Walp.) on Physical Performance in Animals and Humans: A Systematic Review and Meta-Analysis. Nutrients. 2025; 17(1):107. https://doi.org/10.3390/nu17010107
Maca, Lepidium meyenii, performance enhancement, athletic performance, endurance, stamina, strength training, muscle growth, fatigue reduction, speed, agility, power output, VO2 max, lactate threshold, muscle damage, recovery time, energy metabolism, hormonal balance, cortisol, antioxidant status, oxidative stress, inflammation, mood, cognition, sleep quality
This new research in Nutrients has exciting news for female athletes! Beetroot juice was shown to significantly improve VO2 max by 4.82%. That's a big deal because VO2 max is a key indicator of aerobic fitness and endurance. But that's not all – the study also found that beetroot juice enhanced breathing efficiency, meaning athletes could use oxygen more effectively during exercise. This combination of benefits could lead to significant improvements in performance.
- Disclaimers:
"This information is for educational purposes only and should not be interpreted as medical advice."
"The study discussed was conducted on a specific group of female athletes. Further research is needed to confirm these findings in larger and more diverse populations."
"Always consult with a qualified healthcare professional before making any changes to your diet or supplement regimen, especially if you have a medical condition or are taking medications."
"This channel does not provide medical advice."
BeetrootJuice #VO2Max #FemaleAthletes #SportsPerformance #EnduranceTraining
A recent study investigated the effects of Salvia miltiorrhiza root extract (Danshen, also known as red sage), at two different dosages (400 mg/day and 800 mg/day), on men with lower urinary tract symptoms (LUTS). The randomized, double-blind, placebo-controlled trial involved 136 male participants. The study found that Danshen, at both dosages, significantly improved LUTS compared to a placebo. This improvement was observed in various aspects of urinary health, including nighttime urination frequency and quality of life. These findings suggest that Danshen may be a promising natural approach for managing LUTS in men.
- Disclaimers:
•"This information is for educational purposes only and should not be interpreted as medical advice."
•"The study discussed was conducted on a specific population (adult males with LUTS). Further research is needed to confirm these findings in other populations."
•"Always consult with a qualified healthcare professional before taking any new supplement, especially if you have a medical condition or are taking medications."
redsage #danshen #Salvia_miltiorrhiza #BPH #prostatehealth #LUTS
Liu, Z.; Wang, W.; Li, C.; Liu, Y.; Qin, X.; Sun, H.; Wang, X.; Wang, C.; Hu, T. A Randomized, Double-Blind, Placebo-Controlled Trial of Salvia miltiorrhiza Extract in the Treatment of Lower Urinary Tract Symptoms in Men. Nutrients 2024, 17, 24. https://doi.org/10.3390/nu17010024
Alchepharma,Ralph Turchiano,citation,research,study,Salvia miltiorrhiza,Danshen,red sage,red root sage,Tan Shen,Chinese sage,lower urinary tract symptoms,LUTS,men's health,prostate health,benign prostatic hyperplasia,BPH,enlarged prostate,nocturia,frequent urination at night,urinary frequency,urgency,weak stream,quality of life,natural remedies,herbal remedies,TCM,clinical trial,research study,prostate supplements,urinary health supplements
Alpha-Ketoglutarate (AKG) is a naturally occurring compound found in the body with a growing list of potential health benefits. While it's been studied for its role in muscle health and exercise performance, research suggests AKG may also offer anti-aging properties, immune system support, and wound healing benefits. AKG is involved in various metabolic processes, including energy production and amino acid synthesis. As we age, AKG levels decline, which may contribute to age-related health issues. Supplementing with AKG could potentially slow down aging processes, boost immunity, and improve overall healthspan.
AlphaKetoglutarate #MuscleProteinSynthesis #AntiCatabolic #MuscleHypertrophy #AKG
Xu M, Zhang Q, Liu X, Lu L, Li Z. Impact of Alpha-Ketoglutarate on Skeletal Muscle Health and Exercise Performance: A Narrative Review. Nutrients. 2024; 16(22):3968. https://doi.org/10.3390/nu16223968
Alpha-Ketoglutarate, AKG, anti-aging, longevity, healthspan, immune system, immunity, wound healing, metabolism, amino acid synthesis, Krebs cycle, NAD+ metabolism, oxidative stress, inflammation, lifespan, age-related decline, supplementation, health benefits, clinical trials, cell function, collagen synthesis, gut health, bone health
This study explored the effects of elderberry extract on testosterone levels in rats experiencing testosterone deficiency syndrome (TDS). The researchers focused on how elderberry extract affected key enzymes involved in testosterone production and metabolism. They found that the extract increased total testosterone levels by 113.4% in the low-dose group, 219.3% in the mid-dose group, and 267.1% in the high-dose group compared to the control group. 1 Importantly, the high-dose group's testosterone levels were restored to levels similar to those of young rats. 2 The extract also increased free testosterone (the active form that's not bound to proteins) and improved sperm motility. 3 Furthermore, the researchers found no negative effects on prostate health, liver function, or kidney function, suggesting that elderberry extract could be a safe and effective natural approach for managing testosterone deficiency.
elderberry #testosterone #menshealth #hormones #naturalremedies #supplements #diet #aging #testosteronedeficiency #lowtestosterone #malehormones #andropause #fertility #libido #energy #moodenhancing #sambucus
Kim J, An J, Song Y, Jang M, Kong H, Kim S. Effect of Elderberry (Sambucus nigra L.) Extract Intake on Normalizing Testosterone Concentration in Testosterone Deficiency Syndrome Rat Model Through Regulation of 17β-HSD, 5α-Reductase, and CYP19A1 Expression. Nutrients. 2024; 16(23):4169. https://doi.org/10.3390/nu16234169
A recent study, the PPaX trial, has shown promising results in preventing preterm birth. By simply chewing xylitol gum twice daily, pregnant women in Malawi experienced a significant reduction in preterm births. The study, involving over 10,000 women, found that those who chewed xylitol gum had a 24% lower risk of preterm birth and a 30% lower risk of low birth weight compared to those who did not. This simple intervention could have a profound impact on global maternal and infant health, particularly in regions with limited access to advanced healthcare.
xylitol #xylitolgum #maternalhealth #preganancy
Valentine et al., A cluster randomized trial of xylitol chewing gum for prevention of preterm birth: The PPaX trial, Med (2024), https://doi.org/10.1016/j.medj.2024.10.016
Alchepharma,Ralph Turchiano,citation,research,study,preterm birth,xylitol,gum,xylitol gum,oral health,periodontal disease,pregnancy complications,maternal health,infant mortality,randomized controlled trial,cluster randomized trial,public health intervention,low birth weight,oral microbiota,inflammation,immune response,oxidative stress,nutritional intervention,global health,developing countries,healthcare disparities,cost-effective interventions
A recent study published in the Journal of Functional Foods delved into the impact of kimchi consumption on body composition. Researchers conducted a randomized, double-blind, placebo-controlled trial, where participants were assigned to either a kimchi or placebo group. After a specific period of kimchi or placebo consumption, the kimchi group exhibited a significant reduction in body fat compared to the placebo group. This suggests that regular kimchi consumption may contribute to weight loss and improved body composition.
kimchi #bodyfat #weightloss #metabolism #Leuconostocmesenteroides
Wooje Lee, Min-Sung Kwon, Ye-Rang Yun, et al. (2024) Effects of kimchi consumption on body fat and intestinal microbiota in overweight participants: A randomized, double-blind, placebo-controlled, single-center clinical trial, Journal of Functional Foods. doi:https://doi.org/10.1016/j.jff.2024.106401. https://www.sciencedirect.com/science/article/pii/S1756464624004031
Alchepharma,Ralph Turchiano,citation,research,study,kimchi,gut microbiota,obesity,weight loss,body composition,probiotics,prebiotics,kimchi starter,fermented foods,metabolic health,inflammatory bowel disease,irritable bowel syndrome,digestive health,microbiome,microbiome diversity,short-chain fatty acids,SCFAs,Leuconostoc mesenteroides,mental health,Korean food,Asian diet,nutrition research,clinical trial,randomized controlled trial,Akkermansia muciniphila
Recent research has shown promising results for using kimchi and cheonggukjang probiotics to combat hair loss. In a clinical study, participants experienced a significant increase in hair count and thickness after just one month of consuming a probiotic product derived from these traditional Korean foods. This suggests that the probiotics may stimulate hair growth by promoting the anagen phase, the active growth phase of the hair cycle. While further research is needed, these findings offer a potential natural solution for those struggling with hair loss.
Park, S. Y., Lee, J. H., Park, J. H., Lee, M. K., Kim, H. J., & Kim, H. J. (2019). Do Kimchi and Cheonggukjang Probiotics as a Functional Food Improve Androgenetic Alopecia? A Clinical Pilot Study. Journal of Microbiology and Biotechnology, 29(1), 1-8.
kimchi #cheonggukjang #probiotics #hairgrowth
kimchi, cheonggukjang, probiotics, functional food, androgenetic alopecia, hair loss, hair growth, hair count, hair thickness, 5-α reductase, DHT, scalp circulation, anagen phase, hair follicle, microbial strategy, nutritional strategy, Korean food, fermented food, gut health, skin health, clinical trial, pilot study, scientific research, medical research
Recent scientific research suggests that jujube seeds, a traditional Chinese medicine, may hold the key to natural brain regeneration. Studies have shown that consuming jujube seeds can improve cognitive function, reduce inflammation in the brain, and even reverse some of the damage caused by neurodegenerative diseases. While more research is needed to fully understand the mechanisms behind these effects, jujube seeds offer a promising natural approach to promoting brain health and potentially reversing age-related cognitive decline.
jujubesseds #dementia #brainhealth
Umeda Tomohiro, Sakai Ayumi, Uekado Rumi, Shigemori Keiko, Nakajima Ryota, Yamana Kei, Tomiyama Takami (2024) Simply crushed Zizyphi spinosi semen prevents neurodegenerative diseases and reverses age-related cognitive decline in mice eLife 13:RP100737 https://doi.org/10.7554/eLife.100737.1
Ziziphus jujuba, jujube seeds, brain regeneration, neurogenesis, neuroprotection, cognitive function, memory impairment, Alzheimer's disease, dementia, Parkinson's disease, oxidative stress, inflammation, neuroinflammation, antioxidant, polyphenol, triterpenoid, flavonoid, animal model, mouse model, in vitro study, cell culture, neuronal differentiation, synaptic plasticity, neurotrophic factor, traditional Chinese medicine
Lemon balm (Melissa officinalis L.) has garnered significant attention for its potential to promote psychological well-being. Research suggests that this herb may exert anxiolytic and antidepressant effects, improve sleep quality, and enhance cognitive function. These benefits are attributed to its diverse phytochemical profile, including compounds like rosmarinic acid, citral, and terpenes. While further rigorous clinical trials are needed, preliminary studies indicate that lemon balm may offer a safe and effective non-pharmacological approach for managing mild to moderate psychological concerns.
LemonBalm #mood #anxiety
Mathews IM, Eastwood J, Lamport DJ, Cozannet RL, Fanca-Berthon P, Williams CM. Clinical Efficacy and Tolerability of Lemon Balm (Melissa officinalis L.) in Psychological Well-Being: A Review. Nutrients. 2024; 16(20):3545. https://doi.org/10.3390/nu16203545
Alchepharma,Ralph Turchiano,citation,research,study,Melissa officinalis,lemon balm,herbal medicine,phytotherapy,anxiolytic,antidepressant,cognitive enhancement,sleep disorders,stress reduction,GABAergic system,cholinergic system,serotonergic system,neurotransmitter,phytochemical,rosmarinic acid,citral,clinical trial,randomized controlled trial (RCT),placebo-controlled trial,psychological well-being,mental health,quality of life,herbal supplement
Pistachios Boost Eye Health: Study Ep. 1213 OCT 2024
A recent study has revealed that incorporating pistachios into your diet could offer significant benefits for your eye health. Researchers discovered that regular pistachio consumption can increase macular pigment optical density, a vital component of the macula, the central part of the retina responsible for sharp, detailed vision. This increase in macular pigment density is linked to a reduced risk of age-related macular degeneration, a leading cause of vision loss in older adults. By understanding the potential positive impact of pistachios on eye health, individuals can make informed choices about their diet and take proactive steps to protect their vision
pistachios #mpod #amd #pigment #nightvision
Scott, T. M., Ogunbodede, O., McKay, D., & Johnson, E. J. (2024). Pistachio consumption increases macular pigment optical density in healthy adults: A randomized controlled trial. The Journal of Nutrition , [Publish Ahead of Print]. https://doi.org/10.1016/j.tjnut.2024.10.022
A groundbreaking new study has revealed a startling connection between extra virgin olive oil and mortality. Researchers in South Italy discovered that individuals who regularly consumed EVOO were significantly less likely to die prematurely, especially those battling non-alcoholic fatty liver disease. This astonishing finding sheds new light on the incredible power of dietary choices and could revolutionize our understanding of longevity and health.
oliveoil #health #mortality #study #NAFLD
"This video delves into the fascinating world of cranberry juice and its potential benefits for skin health. A recent randomized controlled trial explored the effects of a polyphenol-rich cranberry beverage on various aspects of skin health in women. The results revealed that regular consumption of this cranberry drink positively impacted skin lipids, skin microbiome, inflammation, and oxidative stress. Discover how this natural beverage could contribute to healthier, more radiant skin."
cranberry #cranberryjuice #wrinkles #skinhealth #antiaging
Christman L, De Benedetto A, Johnson E, Khoo C, Gu L. Polyphenol-Rich Cranberry Beverage Positively Affected Skin Health, Skin Lipids, Skin Microbiome, Inflammation, and Oxidative Stress in Women in a Randomized Controlled Trial. Nutrients. 2024; 16(18):3126. https://doi.org/10.3390/nu16183126
skin, cranberry, juice, aging, wrinkles, antioxidants, collagen, elastin, elasticity, firmness, texture, fine lines, wrinkles, sagging, premature aging, photoaging, sun damage, UV rays, free radicals, oxidative stress, inflammation, microbiome, skin barrier, hydration, moisture, youthful, radiant, glowing, natural, beverage, nutrition, dermatology, clinical, research
This video delves into the potential benefits of creatine supplementation for firefighters, tactical athletes, and warfighters. Based on a comprehensive review of scientific literature, we explore the physiological mechanisms underlying creatine's effects on muscle strength, power, and endurance. By examining the unique physical demands of these professions, we discuss how creatine supplementation may enhance performance, reduce fatigue, and improve overall physical fitness. We also address potential safety concerns and provide recommendations for proper creatine dosage and supplementation strategies.
creatine #creatinebenefits #creatinesupplementation #creatineperformance #creatineresearch
Gonzalez DE, Forbes SC, Zapp A, Jagim A, Luedke J, Dickerson BL, Root A, Gil A, Johnson SE, Coles M, et al. Fueling the Firefighter and Tactical Athlete with Creatine: A Narrative Review of a Key Nutrient for Public Safety. Nutrients. 2024; 16(19):3285. https://doi.org/10.3390/nu16193285
Alchepharma,Ralph Turchiano,citation,research,study,creatine,creatine supplementation,creatine benefits,muscle strength,muscle power,muscle endurance,athletic performance,firefighter performance,tactical athlete performance,warfighter performance,creatine for athletes,creatine for strength training,creatine for weightlifting,creatine for military personnel,creatine for law enforcement,creatine for first responders,creatine research,creatine studies
This is a research paper about sports supplements and the effects of five different supplements on athletic performance. The five supplements studied are creatine, beta-alanine, nitrates, caffeine, and protein. The article discusses how creatine increases muscle strength and power, beta-alanine reduces fatigue during exercise, nitrates improve endurance, caffeine reduces pain and improves focus, and protein helps muscles grow and recover.
sportsupplements #athleticperformance #creatine #betaalanine #nitrates
Antonio J, Pereira F, Curtis J, Rojas J, Evans C. The Top 5 Can’t-Miss Sport Supplements. Nutrients. 2024; 16(19):3247. https://doi.org/10.3390/nu16193247
sports supplements, athletic performance, creatine, beta-alanine, nitrates, caffeine, protein, muscle strength, power, fatigue, endurance, pain, focus, muscle growth, recovery, exercise, supplements, nutrition, fitness, workout, health, bodybuilding, weightlifting, sports, athletes
"This study investigates the potential of blackcurrant supplementation to mitigate postmenopausal bone loss. Previous research has demonstrated the beneficial effects of blackcurrants on bone health in animal models. In this randomized controlled trial, we examined the impact of blackcurrant supplementation on whole-body bone mineral density in peri- and early post-menopausal women. Our findings suggest that blackcurrant supplementation can effectively prevent bone loss and may even promote bone gain in this population. These results highlight the potential of dietary interventions to address the health challenges associated with menopause."
Blackcurrants #BoneHealth #PostmenopausalOsteoporosis #GutMicrobiome #NaturalRemedies
Nosal BM, Thornton SN, Darooghegi Mofrad M, Sakaki JR, Mahoney KJ, Macdonald Z, Daddi L, Tran TDB, Weinstock G, Zhou Y, Lee EC, Chun OK. Blackcurrants shape gut microbiota profile and reduce risk of postmenopausal osteoporosis via the gut-bone axis: Evidence from a pilot randomized controlled trial. J Nutr Biochem. 2024 Nov;133:109701. doi: 10.1016/j.jnutbio.2024.109701. Epub 2024 Jul 15. PMID: 39019119.
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"This study investigates the potential of blackcurrant supplementation to mitigate postmenopausal bone loss. Previous research has demonstrated the beneficial effects of blackcurrants on bone health in animal models. In this randomized controlled trial, we examined the impact of blackcurrant supplementation on whole-body bone mineral density in peri- and early post-menopausal women. Our findings suggest that blackcurrant supplementation can effectively prevent bone loss and may even promote bone gain in this population. These results highlight the potential of dietary interventions to address the health challenges associated with menopause."
Blackcurrants #BoneHealth #PostmenopausalOsteoporosis #GutMicrobiome #NaturalRemedies
Nosal BM, Thornton SN, Darooghegi Mofrad M, Sakaki JR, Mahoney KJ, Macdonald Z, Daddi L, Tran TDB, Weinstock G, Zhou Y, Lee EC, Chun OK. Blackcurrants shape gut microbiota profile and reduce risk of postmenopausal osteoporosis via the gut-bone axis: Evidence from a pilot randomized controlled trial. J Nutr Biochem. 2024 Nov;133:109701. doi: 10.1016/j.jnutbio.2024.109701. Epub 2024 Jul 15. PMID: 39019119.
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This video presents a compelling case for the efficacy of hypertonic saline nasal drops in mitigating the symptoms and duration of the common cold in young children. A recent randomized controlled trial, presented at the European Respiratory Society Congress, demonstrated that the use of saline drops significantly reduced the overall duration of illness compared to conventional care. The underlying mechanism, involving the enhancement of cellular defense mechanisms, is explained in detail. Additionally, the potential for reducing the transmission of the cold virus to family members is highlighted. This video offers valuable insights for parents seeking safe and effective strategies to manage their children's respiratory health.
hypertonic_saline_nasal_drops #common_cold #salinesolution #saltwater #cold
[1] Abstract no: OA1985 “A randomised controlled trial of hypertonic saline nose drops as a treatment in children with the common cold (ELVIS-Kids trial)”, by Dr Sandeep Ramalingam et al; Presented in session “Advancements in paediatric infectious respiratory health” at 15:45–17:00 CEST on Sunday 8 September 2024.
hypertonic saline nasal drops, common cold, pediatric health, child health, natural remedies, randomized controlled trial, clinical research, public health, evidence-based medicine, pediatric respiratory health, ELVIS-Kids trial, European Respiratory Society, ERS Congress, saltwater nose drops, child health research, cold symptoms, viral replication, immune system, nasal congestion, sinusitis, upper respiratory infection, antiviral therapy, pediatrics, health care, medical research, health science
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This video presents a compelling case for the efficacy of hypertonic saline nasal drops in mitigating the symptoms and duration of the common cold in young children. A recent randomized controlled trial, presented at the European Respiratory Society Congress, demonstrated that the use of saline drops significantly reduced the overall duration of illness compared to conventional care. The underlying mechanism, involving the enhancement of cellular defense mechanisms, is explained in detail. Additionally, the potential for reducing the transmission of the cold virus to family members is highlighted. This video offers valuable insights for parents seeking safe and effective strategies to manage their children's respiratory health.#hypertonic_saline_nasal_drops #common_cold #salinesolution #saltwater #cold [1] Abstract no: OA1985 “A randomised controlled trial of hypertonic saline nose drops as a treatment in children with the common cold (ELVIS-Kids trial)”, by Dr Sandeep Ramalingam et al; Presented in session “Advancements in paediatric infectious respiratory health” at 15:45–17:00 CEST on Sunday 8 September 2024.hypertonic saline nasal drops, common cold, pediatric health, child health, natural remedies, randomized controlled trial, clinical research, public health, evidence-based medicine, pediatric respiratory health, ELVIS-Kids trial, European Respiratory Society, ERS Congress, saltwater nose drops, child health research, cold symptoms, viral replication, immune system, nasal congestion, sinusitis, upper respiratory infection, antiviral therapy, pediatrics, health care, medical research, health science
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This video presents a compelling case for the efficacy of hypertonic saline nasal drops in mitigating the symptoms and duration of the common cold in young children. A recent randomized controlled trial, presented at the European Respiratory Society Congress, demonstrated that the use of saline drops significantly reduced the overall duration of illness compared to conventional care. The underlying mechanism, involving the enhancement of cellular defense mechanisms, is explained in detail. Additionally, the potential for reducing the transmission of the cold virus to family members is highlighted. This video offers valuable insights for parents seeking safe and effective strategies to manage their children's respiratory health.#hypertonic_saline_nasal_drops #common_cold #salinesolution #saltwater #cold [1] Abstract no: OA1985 “A randomised controlled trial of hypertonic saline nose drops as a treatment in children with the common cold (ELVIS-Kids trial)”, by Dr Sandeep Ramalingam et al; Presented in session “Advancements in paediatric infectious respiratory health” at 15:45–17:00 CEST on Sunday 8 September 2024.hypertonic saline nasal drops, common cold, pediatric health, child health, natural remedies, randomized controlled trial, clinical research, public health, evidence-based medicine, pediatric respiratory health, ELVIS-Kids trial, European Respiratory Society, ERS Congress, saltwater nose drops, child health research, cold symptoms, viral replication, immune system, nasal congestion, sinusitis, upper respiratory infection, antiviral therapy, pediatrics, health care, medical research, health science
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The Liver-Healthy Benefits of Camu-Camu Ep. 1206 SEP 2024
Recent research suggests that camu-camu, a vibrant Amazonian fruit packed with antioxidants, may offer significant benefits for liver health. Studies have shown that camu-camu consumption can help reduce hepatic steatosis and improve liver function markers, particularly in individuals with excess weight and high triglycerides.
CamuCamu #HepaticSteatosis #LiverHealth #AST #ALT
Agrinier AL, Morissette A, Daoust L, Gignac T, Marois J, Varin TV, Pilon G, Larose É, Gagnon C, Desjardins Y, Anhê FF, Carreau AM, Vohl MC, Marette A. Camu-camu decreases hepatic steatosis and liver injury markers in overweight, hypertriglyceridemic individuals: A randomized crossover trial. Cell Rep Med. 2024 Aug 20;5(8):101682. doi: 10.1016/j.xcrm.2024.101682. PMID: 39168095.
liver health, camu-camu, camu camu, hepatic steatosis, antioxidants, natural remedies, weight management, hypertriglyceridemia, metabolic health, non-alcoholic fatty liver disease (NAFLD), cirrhosis, liver injury markers, liver function, dietary supplements, nutrition, health science, medical research, clinical trials, randomized controlled trials, systematic reviews, meta-analyses
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The Liver-Healthy Benefits of Camu-Camu Ep. 1206 SEP 2024
Recent research suggests that camu-camu, a vibrant Amazonian fruit packed with antioxidants, may offer significant benefits for liver health. Studies have shown that camu-camu consumption can help reduce hepatic steatosis and improve liver function markers, particularly in individuals with excess weight and high triglycerides.
CamuCamu #HepaticSteatosis #LiverHealth #AST #ALT
Agrinier AL, Morissette A, Daoust L, Gignac T, Marois J, Varin TV, Pilon G, Larose É, Gagnon C, Desjardins Y, Anhê FF, Carreau AM, Vohl MC, Marette A. Camu-camu decreases hepatic steatosis and liver injury markers in overweight, hypertriglyceridemic individuals: A randomized crossover trial. Cell Rep Med. 2024 Aug 20;5(8):101682. doi: 10.1016/j.xcrm.2024.101682. PMID: 39168095.
liver health, camu-camu, camu camu, hepatic steatosis, antioxidants, natural remedies, weight management, hypertriglyceridemia, metabolic health, non-alcoholic fatty liver disease (NAFLD), cirrhosis, liver injury markers, liver function, dietary supplements, nutrition, health science, medical research, clinical trials, randomized controlled trials, systematic reviews, meta-analyses
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This study explores the science behind coffee and body composition. Researchers compared lightly roasted coffee to regular roasted coffee and found that both can help reduce body fat. But there's a twist: lightly roasted coffee might be even more effective! Tune in to find out why and get motivated to brew your next cup.
coffee #fitness #fitness #regularroastcoffee #bodycomposition #coffeetime
Fernández-Cardero Á, Sierra-Cinos JL, Bravo L, Sarriá B. Consumption of a Coffee Rich in Phenolic Compounds May Improve the Body Composition of People with Overweight or Obesity: Preliminary Insights from a Randomized, Controlled and Blind Crossover Study. Nutrients. 2024; 16(17):2848. https://doi.org/10.3390/nu16172848
coffee, roast level, weight loss, body composition, fat mass, body fat percentage, lightly roasted coffee, regular roasted coffee, middle-aged adults, overweight, obesity, caffeine, antioxidants, metabolism, thermogenesis, gut health, microbiome, inflammation, blood sugar, insulin, blood pressure, cholesterol, heart health, weight management, healthy lifestyle, coffee consumption, scientific research, health benefits
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Roast Matters: Coffee and Body Fat Ep. 1205 SEP 2024
This study explores the science behind coffee and body composition. Researchers compared lightly roasted coffee to regular roasted coffee and found that both can help reduce body fat. But there's a twist: lightly roasted coffee might be even more effective! Tune in to find out why and get motivated to brew your next cup.
coffee #fitness #fitness #regularroastcoffee #bodycomposition #coffeetime
Fernández-Cardero Á, Sierra-Cinos JL, Bravo L, Sarriá B. Consumption of a Coffee Rich in Phenolic Compounds May Improve the Body Composition of People with Overweight or Obesity: Preliminary Insights from a Randomized, Controlled and Blind Crossover Study. Nutrients. 2024; 16(17):2848. https://doi.org/10.3390/nu16172848
coffee, roast level, weight loss, body composition, fat mass, body fat percentage, lightly roasted coffee, regular roasted coffee, middle-aged adults, overweight, obesity, caffeine, antioxidants, metabolism, thermogenesis, gut health, microbiome, inflammation, blood sugar, insulin, blood pressure, cholesterol, heart health, weight management, healthy lifestyle, coffee consumption, scientific research, health benefits
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A groundbreaking study from UCLA Health reveals the potential of Manuka honey as a natural alternative for breast cancer treatment. Researchers discovered that Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer, while also showing promise in targeting cancer cells specifically. This exciting research offers hope for natural, less invasive approaches to breast cancer therapy.
manukahoney #breastcancer #cancer #research #study #clinicaltrials #UCLA #alternativemedicine #naturaltherapy #ERpositive #hormonepositive #breastcancersurvivor
Márquez-Garbán DC, Yanes CD, Llarena G, Elashoff D, Hamilton N, Hardy M, Wadehra M, McCloskey SA, Pietras RJ. Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models. Nutrients. 2024; 16(14):2369. https://doi.org/10.3390/nu16142369
manuka honey, breast cancer, cancer, research, study, clinical trials, UCLA, alternative medicine, natural therapy, ER-positive, hormone-positive, breast cancer survivor, preclinical study, scientific study, potential, treatment, natural remedies, health, healthcare, health tips, cancer awareness, prevention, medicine, science, medical research, medical studies, medical trials
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A groundbreaking study from UCLA Health reveals the potential of Manuka honey as a natural alternative for breast cancer treatment. Researchers discovered that Manuka honey significantly reduced tumor growth in mice with ER-positive breast cancer, while also showing promise in targeting cancer cells specifically. This exciting research offers hope for natural, less invasive approaches to breast cancer therapy.
manukahoney #breastcancer #cancer #research #study #clinicaltrials #UCLA #alternativemedicine #naturaltherapy #ERpositive #hormonepositive #breastcancersurvivor
Márquez-Garbán DC, Yanes CD, Llarena G, Elashoff D, Hamilton N, Hardy M, Wadehra M, McCloskey SA, Pietras RJ. Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models. Nutrients. 2024; 16(14):2369. https://doi.org/10.3390/nu16142369
manuka honey, breast cancer, cancer, research, study, clinical trials, UCLA, alternative medicine, natural therapy, ER-positive, hormone-positive, breast cancer survivor, preclinical study, scientific study, potential, treatment, natural remedies, health, healthcare, health tips, cancer awareness, prevention, medicine, science, medical research, medical studies, medical trials
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A new Australian study has highlighted the importance of magnesium in preventing accelerated aging. By reducing DNA damage and protecting against chronic diseases, magnesium plays a crucial role in preserving cellular health. The research suggests that maintaining adequate magnesium levels through dietary intake or supplementation could potentially slow down the aging process and reduce the risk of age-related health problems.
magnesium #health #antiaging #diseaseprevention #cancer #dnadamage #cellularhealth #alzheimers #parkinsons #cancer #diabetes #hearthealth #brainhealth
Dhillon, V.S., Deo, P. & Fenech, M. Low magnesium in conjunction with high homocysteine increases DNA damage in healthy middle aged Australians. Eur J Nutr (2024). https://doi.org/10.1007/s00394-024-03449-0
magnesium, disease risk, DNA damage, chronic diseases, Alzheimer's, Parkinson's, cancer, diabetes, heart health, brain health, nutrition, supplements, cellular health, aging, anti-aging, longevity, health, wellness, lifestyle, healthy living, public health, medical research, scientific studies, health tips, medical advice, health information
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A new Australian study has highlighted the importance of magnesium in preventing accelerated aging. By reducing DNA damage and protecting against chronic diseases, magnesium plays a crucial role in preserving cellular health. The research suggests that maintaining adequate magnesium levels through dietary intake or supplementation could potentially slow down the aging process and reduce the risk of age-related health problems.
magnesium #health #antiaging #diseaseprevention #cancer #dnadamage #cellularhealth #alzheimers #parkinsons #cancer #diabetes #hearthealth #brainhealth
Dhillon, V.S., Deo, P. & Fenech, M. Low magnesium in conjunction with high homocysteine increases DNA damage in healthy middle aged Australians. Eur J Nutr (2024). https://doi.org/10.1007/s00394-024-03449-0
magnesium, disease risk, DNA damage, chronic diseases, Alzheimer's, Parkinson's, cancer, diabetes, heart health, brain health, nutrition, supplements, cellular health, aging, anti-aging, longevity, health, wellness, lifestyle, healthy living, public health, medical research, scientific studies, health tips, medical advice, health information
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Aging is often accompanied by a decline in organ function, and the urinary tract is no exception. This video explores how cellular aging within the bladder contributes to increased vulnerability to urinary tract infections (UTIs). By understanding these age-related changes, we aim to identify potential anti-aging strategies that can improve bladder health and reduce the risk of UTIs. Our research offers insights into preserving urinary tract function as we age and highlights the potential of natural compounds like D-mannose in supporting overall well-being.
aging #mannose #urinarytractinfection #UTI #bladderhealth #autophagy #oxidativestress #Dmannose #cellularaging #antiaging #urothelialcells
Joshi CS, Salazar AM, Wang C, Ligon MM, Chappidi RR, Fashemi BE, Felder PA, Mora A, Grimm SL, Coarfa C, Mysorekar IU. D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder. Dev Cell. 2024 Jan 8;59(1):33-47.e5. doi: 10.1016/j.devcel.2023.11.017. Epub 2023 Dec 14. PMID: 38101412; PMCID: PMC10872954.
Alchepharma,Ralph Turchiano,citation,research,study,aging,urinary tract infection,UTI,bladder health,autophagy,D-mannose,cellular aging,anti-aging,urothelial cells,bladder dysfunction,recurrent UTI,age-related UTI,mannose supplementation,bladder inflammation,urothelium,lysosomes,cellular debris,reactive oxygen species,ROS,cell death,exfoliation,bladder integrity,mouse model,UTI susceptibility,aging process,urinary tract health,D-mannose benefits
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Aging is often accompanied by a decline in organ function, and the urinary tract is no exception. This video explores how cellular aging within the bladder contributes to increased vulnerability to urinary tract infections (UTIs). By understanding these age-related changes, we aim to identify potential anti-aging strategies that can improve bladder health and reduce the risk of UTIs. Our research offers insights into preserving urinary tract function as we age and highlights the potential of natural compounds like D-mannose in supporting overall well-being.
aging #mannose #urinarytractinfection #UTI #bladderhealth #autophagy #oxidativestress #Dmannose #cellularaging #antiaging #urothelialcells
Joshi CS, Salazar AM, Wang C, Ligon MM, Chappidi RR, Fashemi BE, Felder PA, Mora A, Grimm SL, Coarfa C, Mysorekar IU. D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder. Dev Cell. 2024 Jan 8;59(1):33-47.e5. doi: 10.1016/j.devcel.2023.11.017. Epub 2023 Dec 14. PMID: 38101412; PMCID: PMC10872954.
Alchepharma,Ralph Turchiano,citation,research,study,aging,urinary tract infection,UTI,bladder health,autophagy,D-mannose,cellular aging,anti-aging,urothelial cells,bladder dysfunction,recurrent UTI,age-related UTI,mannose supplementation,bladder inflammation,urothelium,lysosomes,cellular debris,reactive oxygen species,ROS,cell death,exfoliation,bladder integrity,mouse model,UTI susceptibility,aging process,urinary tract health,D-mannose benefits
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A new study shows a butyrate-based supplement can help people with fatty liver disease. Participants with fatty liver and metabolic syndrome took either the supplement or a placebo for 3 months. Those taking the supplement saw significant improvements in liver health markers like FLI and reduced levels of harmful fats in the blood.
While more research is needed, these results are promising for finding new treatments for fatty liver disease.
fattyliver #NAFLD #butyrate #metaboliscsyndrome #liverhealth #liverdisease #guthealth #nutritionresearch #supplementation #dietandhealth #zinc #vitamind
Fogacci F, Giovannini M, Di Micoli V, Grandi E, Borghi C, Cicero AFG. Effect of Supplementation of a Butyrate-Based Formula in Individuals with Liver Steatosis and Metabolic Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2024; 16(15):2454. https://doi.org/10.3390/nu16152454
butyrate, fatty liver disease, NAFLD, metabolic syndrome, liver steatosis, gut microbiota, short-chain fatty acids, inflammation, insulin resistance, obesity, zinc, vitamin D, clinical trial, randomized controlled trial, placebo-controlled, supplementation, dietary intervention, liver enzymes, lipid profile, quality of life, patient outcomes, hepatic fibrosis
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A new study shows a butyrate-based supplement can help people with fatty liver disease. Participants with fatty liver and metabolic syndrome took either the supplement or a placebo for 3 months. Those taking the supplement saw significant improvements in liver health markers like FLI and reduced levels of harmful fats in the blood.
While more research is needed, these results are promising for finding new treatments for fatty liver disease.
fattyliver #NAFLD #butyrate #metaboliscsyndrome #liverhealth #liverdisease #guthealth #nutritionresearch #supplementation #dietandhealth #zinc #vitamind
Fogacci F, Giovannini M, Di Micoli V, Grandi E, Borghi C, Cicero AFG. Effect of Supplementation of a Butyrate-Based Formula in Individuals with Liver Steatosis and Metabolic Syndrome: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Nutrients. 2024; 16(15):2454. https://doi.org/10.3390/nu16152454
butyrate, fatty liver disease, NAFLD, metabolic syndrome, liver steatosis, gut microbiota, short-chain fatty acids, inflammation, insulin resistance, obesity, zinc, vitamin D, clinical trial, randomized controlled trial, placebo-controlled, supplementation, dietary intervention, liver enzymes, lipid profile, quality of life, patient outcomes, hepatic fibrosis
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A groundbreaking study reveals that the over-the-counter supplement nicotinamide riboside can significantly improve walking ability in patients with peripheral artery disease (PAD). Participants in a six-month trial experienced a remarkable increase in walking distance, while those taking a placebo saw a decline. This affordable and accessible supplement offers new hope for millions living with this debilitating condition, potentially revolutionizing treatment options.
nicotinamide_riboside #peripheral_artery_disease #PAD #clinical_trial #vitamin_B3
McDermott, M.M., Martens, C.R., Domanchuk, K.J. et al. Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial. Nat Commun 15, 5046 (2024). https://doi.org/10.1038/s41467-024-49092-5
nicotinamide riboside, peripheral artery disease, PAD, walking endurance, clinical trial, NAD, energy metabolism, muscle function, blood flow, DNA repair, randomized controlled trial, placebo, gastrocnemius, satellite cells, supplement, vitamin B3, over-the-counter, chronic leg disease, treatment options, exercise, rehabilitation, patient outcomes, quality of life, cost-effectiveness, healthcare, geriatrics, cardiology
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A groundbreaking study reveals that the over-the-counter supplement nicotinamide riboside can significantly improve walking ability in patients with peripheral artery disease (PAD). Participants in a six-month trial experienced a remarkable increase in walking distance, while those taking a placebo saw a decline. This affordable and accessible supplement offers new hope for millions living with this debilitating condition, potentially revolutionizing treatment options.
nicotinamide_riboside #peripheral_artery_disease #PAD #clinical_trial #vitamin_B3
McDermott, M.M., Martens, C.R., Domanchuk, K.J. et al. Nicotinamide riboside for peripheral artery disease: the NICE randomized clinical trial. Nat Commun 15, 5046 (2024). https://doi.org/10.1038/s41467-024-49092-5
nicotinamide riboside, peripheral artery disease, PAD, walking endurance, clinical trial, NAD, energy metabolism, muscle function, blood flow, DNA repair, randomized controlled trial, placebo, gastrocnemius, satellite cells, supplement, vitamin B3, over-the-counter, chronic leg disease, treatment options, exercise, rehabilitation, patient outcomes, quality of life, cost-effectiveness, healthcare, geriatrics, cardiology
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This video explores the "sleep-low method," a dietary strategy involving short-term nighttime carbohydrate restriction. A recent study published in Nutrients investigated its impact on exercise performance and fat metabolism in young adults. Participants followed a two-week protocol with daily exercise and either unrestricted or nighttime carbohydrate restriction after 4 pm. The sleep-low group displayed significant improvements in peak oxygen consumption, workload capacity, and respiratory exchange ratio, indicating enhanced fat utilization. These findings suggest the sleep-low method may be a promising strategy for individuals seeking to optimize exercise efficiency and potentially manage weight through increased fat metabolism.
vo2max #fatmetabolism #carbohydrates
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This new study suggests prunes might be a tasty way for older women to keep their bones strong! While doctors usually rely on flat X-rays, this research used fancy 3D scans to get a better look at bone health. Women over 50 were given no prunes, a small handful (4-6) daily, or a bigger handful for a year. The women who enjoyed some prunes daily showed no weakening in their shin bones, while those who skipped them entirely did. Prunes might have bone-friendly ingredients and the smaller handful seems easier to manage as a daily habit.
prunes #bonestrength #osteoporosis
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This new study suggests prunes might be a tasty way for older women to keep their bones strong! While doctors usually rely on flat X-rays, this research used fancy 3D scans to get a better look at bone health. Women over 50 were given no prunes, a small handful (4-6) daily, or a bigger handful for a year. The women who enjoyed some prunes daily showed no weakening in their shin bones, while those who skipped them entirely did. Prunes might have bone-friendly ingredients and the smaller handful seems easier to manage as a daily habit.
prunes #bonestrength #osteoporosis
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This video explores the "sleep-low method," a dietary strategy involving short-term nighttime carbohydrate restriction. A recent study published in Nutrients investigated its impact on exercise performance and fat metabolism in young adults. Participants followed a two-week protocol with daily exercise and either unrestricted or nighttime carbohydrate restriction after 4 pm. The sleep-low group displayed significant improvements in peak oxygen consumption, workload capacity, and respiratory exchange ratio, indicating enhanced fat utilization. These findings suggest the sleep-low method may be a promising strategy for individuals seeking to optimize exercise efficiency and potentially manage weight through increased fat metabolism.
vo2max #fatmetabolism #carbohydrates
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Multiple studies explored the potential of dietary components to influence women's health. In endometriosis, pilot studies on quercetin, resveratrol, and curcumin-containing polyphenols suggest pain reduction. Similarly, a pilot trial investigating dihydroartemisinin, an antimalarial drug, in PCOS patients yielded promising results for regulating menstrual cycles. For postmenopausal women, another pilot study demonstrated improved endothelial function, a marker of heart health, following beetroot juice supplementation. These findings highlight the need for further investigation through larger trials to confirm the efficacy and understand the mechanisms by which these dietary interventions may impact various aspects of women's health.
pcos #endometriosis #hearthealth
Markowska A, Antoszczak M, Markowska J, Huczyński A. The Role of Selected Dietary Factors in the Development and Course of Endometriosis. Nutrients. 2023; 15(12):2773. https://doi.org/10.3390/nu15122773
Liu, Y., Ye, Y., Ding, M., Tang, Y., Li, W., & Dong, X. (2024). Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction. Science. https://doi.org/adk5382
Delgado Spicuzza, J. M., Gosalia, J., Zhong, L., Bondonno, C., Petersen, K. S., De Souza, M. J., Alipour, E., B., D., Somani, Y. B., & Proctor, D. N. (2024). Seven-day dietary nitrate supplementation clinically significantly improves basal macrovascular function in postmenopausal women: A randomized, placebo-controlled, double-blind, crossover clinical trial. Frontiers in Nutrition, 11, 1359671. https://doi.org/10.3389/fnut.2024.1359671
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Emerging Data on Diet & Endometriosis, PCOS, Heart Health Ep. 1195 JUN 2024
Multiple studies explored the potential of dietary components to influence women's health. In endometriosis, pilot studies on quercetin, resveratrol, and curcumin-containing polyphenols suggest pain reduction. Similarly, a pilot trial investigating dihydroartemisinin, an antimalarial drug, in PCOS patients yielded promising results for regulating menstrual cycles. For postmenopausal women, another pilot study demonstrated improved endothelial function, a marker of heart health, following beetroot juice supplementation. These findings highlight the need for further investigation through larger trials to confirm the efficacy and understand the mechanisms by which these dietary interventions may impact various aspects of women's health.
pcos #endometriosis #hearthealth
Markowska A, Antoszczak M, Markowska J, Huczyński A. The Role of Selected Dietary Factors in the Development and Course of Endometriosis. Nutrients. 2023; 15(12):2773. https://doi.org/10.3390/nu15122773
Liu, Y., Ye, Y., Ding, M., Tang, Y., Li, W., & Dong, X. (2024). Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction. Science. https://doi.org/adk5382
Delgado Spicuzza, J. M., Gosalia, J., Zhong, L., Bondonno, C., Petersen, K. S., De Souza, M. J., Alipour, E., B., D., Somani, Y. B., & Proctor, D. N. (2024). Seven-day dietary nitrate supplementation clinically significantly improves basal macrovascular function in postmenopausal women: A randomized, placebo-controlled, double-blind, crossover clinical trial. Frontiers in Nutrition, 11, 1359671. https://doi.org/10.3389/fnut.2024.1359671
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This video explores a scientific study on how Cordyceps militaris, a type of mushroom extract, might benefit long-distance runners. The researchers found that runners who took this extract for 16 weeks showed signs of improved iron levels and reduced muscle damage compared to those who took a placebo. This suggests Cordyceps militaris could be helpful for runners during pre-season training by potentially preventing anemia and muscle injury.
Cordyceps #Anemia #SportsScience
Nakamura, A., Shinozaki, E., Suzuki, Y., Santa, K., Kumazawa, Y., Kobayashi, F., Nagaoka, I., & Koikawa, N. (2024). Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners. Nutrients, 16(12), 1835. https://doi.org/10.3390/nu16121835
Cordyceps , Cordyceps militaris, anemia, iron, runners, muscle damage, creatine kinase, exercise physiology, placebo-controlled, double-blind, sports nutrition, supplementation, pre-season training, hemoglobin, hematocrit, ergogenic effects, recovery, bioavailability, high-altitude training.
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This video explores a scientific study on how Cordyceps militaris, a type of mushroom extract, might benefit long-distance runners. The researchers found that runners who took this extract for 16 weeks showed signs of improved iron levels and reduced muscle damage compared to those who took a placebo. This suggests Cordyceps militaris could be helpful for runners during pre-season training by potentially preventing anemia and muscle injury.
Cordyceps #Anemia #SportsScience
Nakamura, A., Shinozaki, E., Suzuki, Y., Santa, K., Kumazawa, Y., Kobayashi, F., Nagaoka, I., & Koikawa, N. (2024). Effect of the Administration of Cordyceps militaris Mycelium Extract on Blood Markers for Anemia in Long-Distance Runners. Nutrients, 16(12), 1835. https://doi.org/10.3390/nu16121835
Cordyceps , Cordyceps militaris, anemia, iron, runners, muscle damage, creatine kinase, exercise physiology, placebo-controlled, double-blind, sports nutrition, supplementation, pre-season training, hemoglobin, hematocrit, ergogenic effects, recovery, bioavailability, high-altitude training.
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This video explores the growing interest in natural products as potential cancer treatments. Researchers are looking to nature for new options alongside existing therapies like surgery and chemotherapy. This video discusses a study that reviewed existing clinical trials and promising natural products. Curcumin, found in turmeric, and flaxseed are just two examples with potential anti-cancer properties. The video concludes that natural products are a promising area for future cancer research.
NaturalOncology
ClinicalPhytotherapy
PhytoOncology
Zhisen Wang, Zhengcheng Liu and Jiao Qu et al. Role of natural products in tumor therapy from basic research and clinical perspectives. Acta Materia Medica. 2024. Vol. 3(2):163-206. DOI: 10.15212/AMM-2023-0050
natural products, clinical trials, cancer treatment, curcumin, flaxseed, lung cancer, breast cancer, ovarian cancer, endometrial cancer, leukemia, rutin, silibinin, EGCG, sulforaphane (SFN), 2-methoxyestradiol (2MeOE), DHA, apoptosis, angiogenesis, pterostilbene
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Natural Hope: Plants & New Cancer Treatments
This video explores the growing interest in natural products as potential cancer treatments. Researchers are looking to nature for new options alongside existing therapies like surgery and chemotherapy. This video discusses a study that reviewed existing clinical trials and promising natural products. Curcumin, found in turmeric, and flaxseed are just two examples with potential anti-cancer properties. The video concludes that natural products are a promising area for future cancer research.
NaturalOncology
ClinicalPhytotherapy
PhytoOncology
Zhisen Wang, Zhengcheng Liu and Jiao Qu et al. Role of natural products in tumor therapy from basic research and clinical perspectives. Acta Materia Medica. 2024. Vol. 3(2):163-206. DOI: 10.15212/AMM-2023-0050
natural products, clinical trials, cancer treatment, curcumin, flaxseed, lung cancer, breast cancer, ovarian cancer, endometrial cancer, leukemia, rutin, silibinin, EGCG, sulforaphane (SFN), 2-methoxyestradiol (2MeOE), DHA, apoptosis, angiogenesis, pterostilbene
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This research examined the potential of tomato juice to combat bacterial infections. The study found that tomato juice effectively eliminated Salmonella Typhi, the cause of typhoid fever, and uropathogenic E. coli, a bacterium associated with urinary tract infections, within 24 hours. The authors suggest these antimicrobial properties stem from naturally occurring peptides in tomatoes. These findings raise the possibility that incorporating tomato juice into one's diet could be a valuable tool for managing certain bacterial infections.
tomato #typhoid #UTI
Kwon RS, Lee GY, Lee S, Song J.2024.Antimicrobial properties of tomato juice and peptides against typhoidal Salmonella. Microbiol Spectr12:e03102-23.https://doi.org/10.1128/spectrum.03102-23
Alchepharma,Ralph Turchiano,citation,research,study,tomato juice,Salmonella Typhi,typhoid fever,uropathogenic E. coli,UTIs,urinary tract infections,foodborne pathogens,antimicrobial properties,tomato-derived antimicrobial peptides,tdAMPs,lifestyle interventions,natural antimicrobials,plant-based antimicrobials,Salmonella Typhimurium,E. coli,cationic peptides,amphipathic peptides,immune system,public health,dietary interventions,antimicrobial resistance
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This research examined the potential of tomato juice to combat bacterial infections. The study found that tomato juice effectively eliminated Salmonella Typhi, the cause of typhoid fever, and uropathogenic E. coli, a bacterium associated with urinary tract infections, within 24 hours. The authors suggest these antimicrobial properties stem from naturally occurring peptides in tomatoes. These findings raise the possibility that incorporating tomato juice into one's diet could be a valuable tool for managing certain bacterial infections.
tomato #typhoid #UTI
Kwon RS, Lee GY, Lee S, Song J.2024.Antimicrobial properties of tomato juice and peptides against typhoidal Salmonella. Microbiol Spectr12:e03102-23.https://doi.org/10.1128/spectrum.03102-23
Alchepharma,Ralph Turchiano,citation,research,study,tomato juice,Salmonella Typhi,typhoid fever,uropathogenic E. coli,UTIs,urinary tract infections,foodborne pathogens,antimicrobial properties,tomato-derived antimicrobial peptides,tdAMPs,lifestyle interventions,natural antimicrobials,plant-based antimicrobials,Salmonella Typhimurium,E. coli,cationic peptides,amphipathic peptides,immune system,public health,dietary interventions,antimicrobial resistance
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Exciting new research suggests urolithin A, a natural compound found in pomegranates, may offer benefits for Alzheimer's disease. In mouse models, urolithin A improved memory and learning, while also reducing hallmarks of Alzheimer's like amyloid beta plaques. This effect appears linked to its ability to promote mitophagy, the removal of damaged mitochondria in brain cells. While human trials are needed, these findings highlight the potential of dietary components for neurodegenerative diseases.
UrolithinA #Mitophagy #Alzheimers
Hou Y, Chu X, Park J-H, et al. Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions. Alzheimer's Dement. 2024; 1-22. https://doi.org/10.1002/alz.13847
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Urolithin A May Fight Memory Loss EP. 1191 MAY 2024
Exciting new research suggests urolithin A, a natural compound found in pomegranates, may offer benefits for Alzheimer's disease. In mouse models, urolithin A improved memory and learning, while also reducing hallmarks of Alzheimer's like amyloid beta plaques. This effect appears linked to its ability to promote mitophagy, the removal of damaged mitochondria in brain cells. While human trials are needed, these findings highlight the potential of dietary components for neurodegenerative diseases.
UrolithinA #Mitophagy #Alzheimers
Hou Y, Chu X, Park J-H, et al. Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions. Alzheimer's Dement. 2024; 1-22. https://doi.org/10.1002/alz.13847
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This research examined the effectiveness and safety of Red Yeast Rice Extract (RYR) for lowering cholesterol. They analyzed data from multiple studies and found that RYR extract significantly reduced total and LDL cholesterol levels, which are the "bad" cholesterols. The reductions were comparable to low-dose statins, medications commonly used for cholesterol control. Importantly, there was no increased risk of serious side effects. While more research is needed, this suggests RYR extract may be a safe and effective option for managing cholesterol levels.#cholesterol #redyeastrice #monacolinTrogkanis, E., Karalexi, M. A., Sergentanis, T. N., Kornarou, E., & Vassilakou, T. (2024). Safety and Efficacy of the Consumption of the Nutraceutical “Red Yeast Rice Extract” for the Reduction of Hypercholesterolemia in Humans: A Systematic Review and Meta-Analysis. Nutrients, 16(10), 1453. https://doi.org/10.3390/nu16101453RedYeastRice, cholesterol, LDL, HDL, triglycerides, hypercholesterolemia, natural remedy, statins, heart health, cardiovascular, meta-analysis, safety, efficacy, RYR extract, monacolin K, side effects, alternative medicine, supplement, clinical trials, blood pressure, diet, lifestyle, prevention, red yeast rice
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This research examined the effectiveness and safety of Red Yeast Rice Extract (RYR) for lowering cholesterol. They analyzed data from multiple studies and found that RYR extract significantly reduced total and LDL cholesterol levels, which are the "bad" cholesterols. The reductions were comparable to low-dose statins, medications commonly used for cholesterol control. Importantly, there was no increased risk of serious side effects. While more research is needed, this suggests RYR extract may be a safe and effective option for managing cholesterol levels.#cholesterol #redyeastrice #monacolinTrogkanis, E., Karalexi, M. A., Sergentanis, T. N., Kornarou, E., & Vassilakou, T. (2024). Safety and Efficacy of the Consumption of the Nutraceutical “Red Yeast Rice Extract” for the Reduction of Hypercholesterolemia in Humans: A Systematic Review and Meta-Analysis. Nutrients, 16(10), 1453. https://doi.org/10.3390/nu16101453RedYeastRice, cholesterol, LDL, HDL, triglycerides, hypercholesterolemia, natural remedy, statins, heart health, cardiovascular, meta-analysis, safety, efficacy, RYR extract, monacolin K, side effects, alternative medicine, supplement, clinical trials, blood pressure, diet, lifestyle, prevention, red yeast rice
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A new study from the University of Cincinnati suggests strawberries might be more than just a delicious treat. Researchers gave overweight middle-aged adults a daily powder supplement with the equivalent of one cup of strawberries. After 12 weeks, those on the strawberry powder showed improvements in memory and reduced symptoms of depression. Scientists believe this might be due to the anti-inflammatory properties of anthocyanins, a type of antioxidant found in strawberries. This is exciting preliminary research, but further studies with larger groups and longer durations are needed to confirm these findings.
StrawberryPower #BrainHealth #MemoryBoost
Krikorian, R., Shidler, M. D., & Summer, S. S. (2023). Early Intervention in Cognitive Aging with Strawberry Supplementation. Nutrients, 15(20), 4431. https://doi.org/10.3390/nu15204431
strawberry, dementia, depression, cognitive, function, memory, UC, Cincinnati, study, overweight, middle-aged, anthocyanins, antioxidant, inflammation, supplement, powder, intervention, executive function, ellagitannin, ellagic acid
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A new study from the University of Cincinnati suggests strawberries might be more than just a delicious treat. Researchers gave overweight middle-aged adults a daily powder supplement with the equivalent of one cup of strawberries. After 12 weeks, those on the strawberry powder showed improvements in memory and reduced symptoms of depression. Scientists believe this might be due to the anti-inflammatory properties of anthocyanins, a type of antioxidant found in strawberries. This is exciting preliminary research, but further studies with larger groups and longer durations are needed to confirm these findings.
StrawberryPower #BrainHealth #MemoryBoost
Krikorian, R., Shidler, M. D., & Summer, S. S. (2023). Early Intervention in Cognitive Aging with Strawberry Supplementation. Nutrients, 15(20), 4431. https://doi.org/10.3390/nu15204431
strawberry, dementia, depression, cognitive, function, memory, UC, Cincinnati, study, overweight, middle-aged, anthocyanins, antioxidant, inflammation, supplement, powder, intervention, executive function, ellagitannin, ellagic acid
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A giant study from Monash University followed over 86,000 people to see how light exposure impacted their mental health. Participants shared their sleep habits, how much light they saw during the day and night, and any mental health diagnoses they had. The big finding? People exposed to more light at night seemed more likely to experience depression, anxiety, and other mental health challenges. But that's not all! People who got plenty of daytime sunshine were less likely to struggle with these conditions. This suggests a simple yet powerful way to support your mental well-being: embrace the sunshine during the day and dim the lights at night.
LightExposureStudy #DaylightMentalHealth #NightLightRisk
Low daytime light and bright night-time light are associated with psychiatric disorders: an objective light study in greater than 85,000 UK Biobank participants Angus C. Burns, Daniel P. Windred, Martin K. Rutter, Patrick Olivier, Céline Vetter, Richa Saxena, Jacqueline M. Lane, Andrew J. K. Phillips, Sean W. Cain medRxiv 2022.10.16.22280934; doi: https://doi.org/10.1101/2022.10.16.22280934
Alchepharma,Ralph Turchiano,citation,research,study,light exposure,mental health,Monash University,large study,depression,anxiety,bipolar disorder,self-harm,psychosis,sleep,circadian rhythm,daytime light,nighttime light,mood,wellbeing,light hygiene,mental health prevention,natural treatment,mental health tips,sunlight,mental health risk factors,blue light,sleep hygiene,dark therapy,light therapy
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A giant study from Monash University followed over 86,000 people to see how light exposure impacted their mental health. Participants shared their sleep habits, how much light they saw during the day and night, and any mental health diagnoses they had. The big finding? People exposed to more light at night seemed more likely to experience depression, anxiety, and other mental health challenges. But that's not all! People who got plenty of daytime sunshine were less likely to struggle with these conditions. This suggests a simple yet powerful way to support your mental well-being: embrace the sunshine during the day and dim the lights at night.
LightExposureStudy #DaylightMentalHealth #NightLightRisk
Low daytime light and bright night-time light are associated with psychiatric disorders: an objective light study in greater than 85,000 UK Biobank participants Angus C. Burns, Daniel P. Windred, Martin K. Rutter, Patrick Olivier, Céline Vetter, Richa Saxena, Jacqueline M. Lane, Andrew J. K. Phillips, Sean W. Cain medRxiv 2022.10.16.22280934; doi: https://doi.org/10.1101/2022.10.16.22280934
Alchepharma,Ralph Turchiano,citation,research,study,light exposure,mental health,Monash University,large study,depression,anxiety,bipolar disorder,self-harm,psychosis,sleep,circadian rhythm,daytime light,nighttime light,mood,wellbeing,light hygiene,mental health prevention,natural treatment,mental health tips,sunlight,mental health risk factors,blue light,sleep hygiene,dark therapy,light therapy
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Struggling with ulcerative colitis flare-ups? This video explores a new study on Indigo Naturalis, a plant-based supplement. Researchers followed patients who achieved remission with Indigo Naturalis and found it very effective in preventing future flare-ups. Even those who relapsed after stopping the supplement saw success when restarting it. This is promising news, but remember, it's one study. Talk to your doctor before trying anything new.
NaturalTreatment #UlcerativeColitis #IndigoNaturalis
Matsuno, Y., Umeno, J., Hirano, A., Fuyuno, Y., Nagasue, T., Fujioka, S., Kawasaki, K., Moriyama, T., & Torisu, T. (2024). MAINTENANCE EFFICACY OF ORAL INDIGO NATURALIS FOR ULCERATIVE COLITIS: A SINGLE-CENTER, OPEN-LABEL, RANDOMIZED, CONTROLLED STUDY. Inflammatory Bowel Diseases, 30(Supplement_1), S9. https://doi.org/10.1093/ibd/izae020.020
Matsuno, Y., Torisu, T., Umeno, J., Shibata, H., Hirano, A., Fuyuno, Y., Okamoto, Y., Fujioka, S., Kawasaki, K., Moriyama, T., Nagasue, T., Zeze, K., Hirakawa, Y., Kawatoko, S., Koga, Y., Oda, Y., Esaki, M., & Kitazono, T. (2022). One-year clinical efficacy and safety of indigo naturalis for active ulcerative colitis: A real-world prospective study. Intestinal Research, 20(2), 260-268. https://doi.org/10.5217/ir.2021.00124
Alchepharma,Ralph Turchiano,citation,research,study,IndigoNaturalis,UlcerativeColitis,remission,maintenance therapy,herbal remedy,plant-based treatment,oral Indigo Naturalis,clinical trial,UC study,gut health,inflammatory bowel disease,flare-up prevention,mucosal healing,relapse rates,single-center study,open-label trial,randomized controlled trial,Mayo endoscopic subscore,dose-dependent effect,year-long study,safety profile,natural medicine
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Struggling with ulcerative colitis flare-ups? This video explores a new study on Indigo Naturalis, a plant-based supplement. Researchers followed patients who achieved remission with Indigo Naturalis and found it very effective in preventing future flare-ups. Even those who relapsed after stopping the supplement saw success when restarting it. This is promising news, but remember, it's one study. Talk to your doctor before trying anything new.
NaturalTreatment #UlcerativeColitis #IndigoNaturalis
Matsuno, Y., Umeno, J., Hirano, A., Fuyuno, Y., Nagasue, T., Fujioka, S., Kawasaki, K., Moriyama, T., & Torisu, T. (2024). MAINTENANCE EFFICACY OF ORAL INDIGO NATURALIS FOR ULCERATIVE COLITIS: A SINGLE-CENTER, OPEN-LABEL, RANDOMIZED, CONTROLLED STUDY. Inflammatory Bowel Diseases, 30(Supplement_1), S9. https://doi.org/10.1093/ibd/izae020.020
Matsuno, Y., Torisu, T., Umeno, J., Shibata, H., Hirano, A., Fuyuno, Y., Okamoto, Y., Fujioka, S., Kawasaki, K., Moriyama, T., Nagasue, T., Zeze, K., Hirakawa, Y., Kawatoko, S., Koga, Y., Oda, Y., Esaki, M., & Kitazono, T. (2022). One-year clinical efficacy and safety of indigo naturalis for active ulcerative colitis: A real-world prospective study. Intestinal Research, 20(2), 260-268. https://doi.org/10.5217/ir.2021.00124
Alchepharma,Ralph Turchiano,citation,research,study,IndigoNaturalis,UlcerativeColitis,remission,maintenance therapy,herbal remedy,plant-based treatment,oral Indigo Naturalis,clinical trial,UC study,gut health,inflammatory bowel disease,flare-up prevention,mucosal healing,relapse rates,single-center study,open-label trial,randomized controlled trial,Mayo endoscopic subscore,dose-dependent effect,year-long study,safety profile,natural medicine
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Researchers are looking at ways to help hair growth, and a new study shows promise with cinnamon! They found a tiny molecule in cinnamon called cinnamic acid that can increase hair growth by helping the body use oxytocin, a hormone important for hair health. In lab tests, cinnamic acid showed results almost as good as oxytocin itself, but with the advantage of being small enough to be absorbed by the scalp. This is exciting news for future hair growth products!
Cinnamonhairoil #Hairgrowthbreakthrough #Naturalhaircare
Kageyama, T., Seo, J., Yan, L., & Fukuda, J. (2024). Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation. Scientific Reports, 14(1), 1-8. https://doi.org/10.1038/s41598-024-55377-y
cinnamon, hair growth, hair loss, new treatment, oxytocin, science, natural, scalp health, longer hair, chinese medicine, cinnamic acid, follicle, cells, lab study, promising results, future products, hair care, men's hair, women's hair, androgenic alopecia, hair loss treatment, hair growth serum, hair growth oil, hair growth shampoo, healthy hair
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Researchers are looking at ways to help hair growth, and a new study shows promise with cinnamon! They found a tiny molecule in cinnamon called cinnamic acid that can increase hair growth by helping the body use oxytocin, a hormone important for hair health. In lab tests, cinnamic acid showed results almost as good as oxytocin itself, but with the advantage of being small enough to be absorbed by the scalp. This is exciting news for future hair growth products!
Cinnamonhairoil #Hairgrowthbreakthrough #Naturalhaircare
Kageyama, T., Seo, J., Yan, L., & Fukuda, J. (2024). Cinnamic acid promotes elongation of hair peg-like sprouting in hair follicle organoids via oxytocin receptor activation. Scientific Reports, 14(1), 1-8. https://doi.org/10.1038/s41598-024-55377-y
cinnamon, hair growth, hair loss, new treatment, oxytocin, science, natural, scalp health, longer hair, chinese medicine, cinnamic acid, follicle, cells, lab study, promising results, future products, hair care, men's hair, women's hair, androgenic alopecia, hair loss treatment, hair growth serum, hair growth oil, hair growth shampoo, healthy hair
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This video explores the potential of Gynostemma pentaphyllum (Jiaogulan) leaf hydrodistillate (GPHD) as a hair growth promoter. We examine in vitro and in vivo studies investigating the hair-inducing properties of GPHD and its major component, damulin B. The video delves into the Wnt/β-catenin pathway and its role in GPHD's hair growth effects, comparing its efficacy to minoxidil.
HairGrowthScience #NaturalHairSolutions #Gynostemma
Kovale L, Lee S, Song M, Lee J, Son HJ, Sung YK, Kwack MH, Choe W, Kang I, Kim SS, et al. Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth-Inducing Properties In Vivo and In Vitro via the Wnt/β-Catenin Pathway in Dermal Papilla Cells. Nutrients. 2024; 16(7):985. https://doi.org/10.3390/nu16070985
Gynostemma pentaphyllum, jiaogulan, hair growth, alopecia, minoxidil, dermal papilla cells, damulin B, hydrodistillate (GPHD), in vivo, in vitro, Wnt/β-catenin pathway, hair growth-inducing properties, growth factors, hair follicle, AKT signaling pathway, proliferation, differentiation, clinical trials
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This video explores the potential of Gynostemma pentaphyllum (Jiaogulan) leaf hydrodistillate (GPHD) as a hair growth promoter. We examine in vitro and in vivo studies investigating the hair-inducing properties of GPHD and its major component, damulin B. The video delves into the Wnt/β-catenin pathway and its role in GPHD's hair growth effects, comparing its efficacy to minoxidil.
HairGrowthScience #NaturalHairSolutions #Gynostemma
Kovale L, Lee S, Song M, Lee J, Son HJ, Sung YK, Kwack MH, Choe W, Kang I, Kim SS, et al. Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth-Inducing Properties In Vivo and In Vitro via the Wnt/β-Catenin Pathway in Dermal Papilla Cells. Nutrients. 2024; 16(7):985. https://doi.org/10.3390/nu16070985
Gynostemma pentaphyllum, jiaogulan, hair growth, alopecia, minoxidil, dermal papilla cells, damulin B, hydrodistillate (GPHD), in vivo, in vitro, Wnt/β-catenin pathway, hair growth-inducing properties, growth factors, hair follicle, AKT signaling pathway, proliferation, differentiation, clinical trials
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This video explores surprising new research on a potential natural remedy for high blood pressure: lemons! Studies suggest citric acid, a key component in lemons, might help lower blood pressure in rats. While the exact mechanism needs further investigation, this discovery opens doors for exploring natural approaches to managing hypertension. Important Note: This information is for educational purposes only and should not be taken as medical advice. Always consult a healthcare professional before making any dietary changes.
LemonPower #NaturalBloodPressure #ScienceDiscovery
Nakamura K, Suzuki Y, Goto K, Yamaguchi S, Hiramitsu M. Antihypertensive and Vasorelaxant Effects of Citric Acid and Lemon Juice in Spontaneously Hypertensive Rats: In Vivo and Ex Vivo Studies. Nutrients. 2023; 15(17):3849. https://doi.org/10.3390/nu15173849
Alchepharma,Ralph Turchiano,citation,research,study,high blood pressure,hypertension,natural remedy,lemon juice,citric acid,blood pressure control,hypertension management,blood pressure reduction,lemon benefits,citric acid health benefits,vasorelaxant effect,DASH diet,vitamin C,flavonoids,antioxidant properties,alternative approaches,scientific discovery,endothelial function,nitric oxide production,arterial stiffness,blood pressure lowering effect
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Lemon Juice Hypertension Discovery Episode 1181 MAR 2024
This video explores surprising new research on a potential natural remedy for high blood pressure: lemons! Studies suggest citric acid, a key component in lemons, might help lower blood pressure in rats. While the exact mechanism needs further investigation, this discovery opens doors for exploring natural approaches to managing hypertension. Important Note: This information is for educational purposes only and should not be taken as medical advice. Always consult a healthcare professional before making any dietary changes.
LemonPower #NaturalBloodPressure #ScienceDiscovery
Nakamura K, Suzuki Y, Goto K, Yamaguchi S, Hiramitsu M. Antihypertensive and Vasorelaxant Effects of Citric Acid and Lemon Juice in Spontaneously Hypertensive Rats: In Vivo and Ex Vivo Studies. Nutrients. 2023; 15(17):3849. https://doi.org/10.3390/nu15173849
Alchepharma,Ralph Turchiano,citation,research,study,high blood pressure,hypertension,natural remedy,lemon juice,citric acid,blood pressure control,hypertension management,blood pressure reduction,lemon benefits,citric acid health benefits,vasorelaxant effect,DASH diet,vitamin C,flavonoids,antioxidant properties,alternative approaches,scientific discovery,endothelial function,nitric oxide production,arterial stiffness,blood pressure lowering effect
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This study explores the exciting potential of lycopene, a natural compound found in tomatoes, for combating liver disease. Researchers followed participants for over a decade, finding a link between higher lycopene intake and a reduced risk of fatty liver disease (NAFLD). The study even identified a specific daily dosage (around 9.5mg) that showed the strongest protective effect. This video will break down the science behind lycopene's potential benefits, including its antioxidant and anti-inflammatory properties, and how it might specifically target liver health.
LycopeneResearch #NALFLDprevention #LiverHealth
Donghia R, Campanella A, Bonfiglio C, Cuccaro F, Tatoli R, Giannelli G. Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study. Nutrients. 2024; 16(4):562. https://doi.org/10.3390/nu16040562
lycopene benefits, liver health foods, foods for fatty liver disease, natural ways to improve liver health, antioxidant rich foods, lycopene and liver disease, NUTRIHEP study, lycopene dosage for liver health, how to reduce risk of NAFLD, is tomato good for liver, non-alcoholic fatty liver disease (NAFLD), antioxidant properties, anti-inflammatory properties, free radicals, liver disease prevention, liver cirrhosis, cardiovascular disease prevention, immune system support, AFLD, FLD
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This study explores the exciting potential of lycopene, a natural compound found in tomatoes, for combating liver disease. Researchers followed participants for over a decade, finding a link between higher lycopene intake and a reduced risk of fatty liver disease (NAFLD). The study even identified a specific daily dosage (around 9.5mg) that showed the strongest protective effect. This video will break down the science behind lycopene's potential benefits, including its antioxidant and anti-inflammatory properties, and how it might specifically target liver health.
LycopeneResearch #NALFLDprevention #LiverHealth
Donghia R, Campanella A, Bonfiglio C, Cuccaro F, Tatoli R, Giannelli G. Protective Role of Lycopene in Subjects with Liver Disease: NUTRIHEP Study. Nutrients. 2024; 16(4):562. https://doi.org/10.3390/nu16040562
lycopene benefits, liver health foods, foods for fatty liver disease, natural ways to improve liver health, antioxidant rich foods, lycopene and liver disease, NUTRIHEP study, lycopene dosage for liver health, how to reduce risk of NAFLD, is tomato good for liver, non-alcoholic fatty liver disease (NAFLD), antioxidant properties, anti-inflammatory properties, free radicals, liver disease prevention, liver cirrhosis, cardiovascular disease prevention, immune system support, AFLD, FLD
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This study reveals a strong link between low levels of both selenium and zinc and significantly reduced survival rates in prostate cancer patients. Our findings suggest that optimizing both elements could be crucial for improving survival outcomes. We call for further research to determine the ideal levels for different regions, paving the way for potential personalized treatment approaches.
ProstateCancerResearch #SeleniumZinc #SurvivalOutcomes
Pietrzak S, Marciniak W, Derkacz R, Matuszczak M, Kiljańczyk A, Baszuk P, Bryśkiewicz M, Sikorski A, Gronwald J, Słojewski M, et al. Correlation between Selenium and Zinc Levels and Survival among Prostate Cancer Patients. Nutrients. 2024; 16(4):527. https://doi.org/10.3390/nu16040527
prostate cancer, selenium, zinc, survival, combined deficiency, prognosis, biomarker, Se, Zn, blood levels, optimal levels, element therapy, micronutrients, essential trace elements, personalized medicine, targeted therapy, dietary factors, cancer treatment, complementary medicine, alternative therapy
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This study reveals a strong link between low levels of both selenium and zinc and significantly reduced survival rates in prostate cancer patients. Our findings suggest that optimizing both elements could be crucial for improving survival outcomes. We call for further research to determine the ideal levels for different regions, paving the way for potential personalized treatment approaches.
ProstateCancerResearch #SeleniumZinc #SurvivalOutcomes
Pietrzak S, Marciniak W, Derkacz R, Matuszczak M, Kiljańczyk A, Baszuk P, Bryśkiewicz M, Sikorski A, Gronwald J, Słojewski M, et al. Correlation between Selenium and Zinc Levels and Survival among Prostate Cancer Patients. Nutrients. 2024; 16(4):527. https://doi.org/10.3390/nu16040527
prostate cancer, selenium, zinc, survival, combined deficiency, prognosis, biomarker, Se, Zn, blood levels, optimal levels, element therapy, micronutrients, essential trace elements, personalized medicine, targeted therapy, dietary factors, cancer treatment, complementary medicine, alternative therapy
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Sun got you down? Say goodbye to wrinkles and hello to youthful skin with a surprising hero: cloves! This study found that feeding mice a special clove extract called isoeugenol while exposing them to sun-like rays actually reversed aging signs! Imagine, smoother, less dry skin and thicker collagen, all thanks to a common spice! Plus, the good news doesn't stop there - the extract even balanced their gut bacteria, which can also impact skin health. This is a game-changer for natural anti-aging solutions! While more research is needed, this spicy discovery is definitely something to get excited about - your skin (and gut) might just thank you for it!
NaturalAntiAging #SpiceUpYourSkincare #GutSkinConnection
Geng, R., Kang, S., Huang, K., & Tong, T. (2024). Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice. Nutrients, 16(4), 481. https://doi.org/10.3390/nu16040481
clove oil, skin aging, wrinkles, sun damage, natural remedy, gut health, anti-aging, mice study, isoeugenol, collagen, UV protection, healthier skin, microbiome, DIY skincare, affordable anti-aging, prevent wrinkles, natural collagen booster, gut bacteria for skin, kitchen ingredient beauty hack, sun protection alternative, healthy aging
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Sun got you down? Say goodbye to wrinkles and hello to youthful skin with a surprising hero: cloves! This study found that feeding mice a special clove extract called isoeugenol while exposing them to sun-like rays actually reversed aging signs! Imagine, smoother, less dry skin and thicker collagen, all thanks to a common spice! Plus, the good news doesn't stop there - the extract even balanced their gut bacteria, which can also impact skin health. This is a game-changer for natural anti-aging solutions! While more research is needed, this spicy discovery is definitely something to get excited about - your skin (and gut) might just thank you for it!
NaturalAntiAging #SpiceUpYourSkincare #GutSkinConnection
Geng, R., Kang, S., Huang, K., & Tong, T. (2024). Dietary Isoeugenol Supplementation Attenuates Chronic UVB-Induced Skin Photoaging and Modulates Gut Microbiota in Mice. Nutrients, 16(4), 481. https://doi.org/10.3390/nu16040481
clove oil, skin aging, wrinkles, sun damage, natural remedy, gut health, anti-aging, mice study, isoeugenol, collagen, UV protection, healthier skin, microbiome, DIY skincare, affordable anti-aging, prevent wrinkles, natural collagen booster, gut bacteria for skin, kitchen ingredient beauty hack, sun protection alternative, healthy aging
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In a scientific knockout, a study found that athletes who consumed both alkaline water and L-glutamine before exercise experienced a significant boost in salivary α-amylase activity, indicating enhanced immunity. They also saw a rise in testosterone levels, potentially indicating faster muscle recovery. While the mechanisms require further investigation, this suggests a possible synergistic effect between the two substances. Although research focuses on athletes, it raises intriguing possibilities for anyone seeking to optimize recovery and potentially improve immune function. Remember, science is always evolving, offering new tools to support your well-being.
SportRecovery #AlkalineWater #LGlutamine
Lu, T., He, C., Suzuki, K., Lu, C., Wang, C., & Fang, S. (2024). Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes. Nutrients, 16(3), 454. https://doi.org/10.3390/nu16030454
boxing, testosterone boost, alkaline water, L-glutamine, immune function, muscle recovery, salivary markers, training performance, athlete study, randomized controlled trial, pre-workout supplement, hydration,, sport science, recovery, glutamine benefits,alkaline water research, amylase, mucosal, immune
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In a scientific knockout, a study found that athletes who consumed both alkaline water and L-glutamine before exercise experienced a significant boost in salivary α-amylase activity, indicating enhanced immunity. They also saw a rise in testosterone levels, potentially indicating faster muscle recovery. While the mechanisms require further investigation, this suggests a possible synergistic effect between the two substances. Although research focuses on athletes, it raises intriguing possibilities for anyone seeking to optimize recovery and potentially improve immune function. Remember, science is always evolving, offering new tools to support your well-being.
SportRecovery #AlkalineWater #LGlutamine
Lu, T., He, C., Suzuki, K., Lu, C., Wang, C., & Fang, S. (2024). Concurrent Ingestion of Alkaline Water and L-Glutamine Enhanced Salivary α-Amylase Activity and Testosterone Concentration in Boxing Athletes. Nutrients, 16(3), 454. https://doi.org/10.3390/nu16030454
boxing, testosterone boost, alkaline water, L-glutamine, immune function, muscle recovery, salivary markers, training performance, athlete study, randomized controlled trial, pre-workout supplement, hydration,, sport science, recovery, glutamine benefits,alkaline water research, amylase, mucosal, immune
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'Furry fruit' improves mental health – fast Ep. 1175 FEB 2024EP
A new study found kiwifruit can significantly boost mood and vitality within just 4 days, faster than vitamin C supplements. While both improved mood, participants consuming kiwifruit saw stronger and earlier effects, suggesting synergistic benefits from the whole fruit's nutrients like fiber, folate, and antioxidants. This highlights the potential of kiwifruit as a readily available and natural way to support mental well-being, even for those with good baseline mental health.
KiwifruitMoodBoost #FastMoodFix #WholeFoodWellness
Benjamin D. Fletcher, Jillian J. Haszard, Margreet C. M. Vissers, Tamlin S. Conner. Smartphone survey data reveals the timecourse of changes in mood outcomes following vitamin C or kiwifruit intervention in adults with low vitamin C. British Journal of Nutrition, 2023; 1 DOI: 10.1017/S0007114523002787
kiwifruit mood boost, kiwifruit mental health, vitamin c mood, kiwifruit study, kiwifruit research, improve mood fast, natural mood boosters, gut health mood, antioxidant mood, depression and food, kiwi youtube video, sunshine gold kiwifruit
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'Furry fruit' improves mental health – fast Ep. 1175 FEB 2024
A new study found kiwifruit can significantly boost mood and vitality within just 4 days, faster than vitamin C supplements. While both improved mood, participants consuming kiwifruit saw stronger and earlier effects, suggesting synergistic benefits from the whole fruit's nutrients like fiber, folate, and antioxidants. This highlights the potential of kiwifruit as a readily available and natural way to support mental well-being, even for those with good baseline mental health.
KiwifruitMoodBoost #FastMoodFix #WholeFoodWellness
Benjamin D. Fletcher, Jillian J. Haszard, Margreet C. M. Vissers, Tamlin S. Conner. Smartphone survey data reveals the timecourse of changes in mood outcomes following vitamin C or kiwifruit intervention in adults with low vitamin C. British Journal of Nutrition, 2023; 1 DOI: 10.1017/S0007114523002787
kiwifruit mood boost, kiwifruit mental health, vitamin c mood, kiwifruit study, kiwifruit research, improve mood fast, natural mood boosters, gut health mood, antioxidant mood, depression and food, kiwi youtube video, sunshine gold kiwifruit
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Combat athletes, facing explosive bursts and grueling rounds, might find a friend in β-alanine. This amino acid, not a direct performance booster, fuels carnosine, a muscle buffer that fights fatigue. Studies suggest 4-6 grams daily for 4 weeks can improve performance in combat-like bursts (60-240 seconds), potentially boosting strength, power, work capacity, and even recovery. While more research is needed, β-alanine, timed with meals, could be a safe weapon in a combat athlete's arsenal, helping them push their limits and dominate the ring.
betaalanine #fightfatigue #CarnosinePower
Fiandor, E. M., García, J. F., Busto, N., & Roche, E. (2023). β-Alanine Supplementation in Combat Sports: Evaluation of Sports Performance, Perception, and Anthropometric Parameters and Biochemical Markers—A Systematic Review of Clinical Trials. Nutrients, 15(17), 3755. https://doi.org/10.3390/nu15173755
beta-alanine, combat sports, fatigue reduction, performance enhancement, carnosine, muscle buffer, strength, power, work capacity, recovery, combat athletes, amino acid, supplement, safety, dosage, timing, research, studies, benefits, drawbacks, effectiveness, scientific evidence, #betaalanine #fightfatigue #CarnosinePower
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Combat athletes, facing explosive bursts and grueling rounds, might find a friend in β-alanine. This amino acid, not a direct performance booster, fuels carnosine, a muscle buffer that fights fatigue. Studies suggest 4-6 grams daily for 4 weeks can improve performance in combat-like bursts (60-240 seconds), potentially boosting strength, power, work capacity, and even recovery. While more research is needed, β-alanine, timed with meals, could be a safe weapon in a combat athlete's arsenal, helping them push their limits and dominate the ring.
betaalanine #fightfatigue #CarnosinePower
Fiandor, E. M., García, J. F., Busto, N., & Roche, E. (2023). β-Alanine Supplementation in Combat Sports: Evaluation of Sports Performance, Perception, and Anthropometric Parameters and Biochemical Markers—A Systematic Review of Clinical Trials. Nutrients, 15(17), 3755. https://doi.org/10.3390/nu15173755
beta-alanine, combat sports, fatigue reduction, performance enhancement, carnosine, muscle buffer, strength, power, work capacity, recovery, combat athletes, amino acid, supplement, safety, dosage, timing, research, studies, benefits, drawbacks, effectiveness, scientific evidence, #betaalanine #fightfatigue #CarnosinePower
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Researchers gave breast cancer patients an extract from the Boswellia tree (aka frankincense) daily before surgery. Comparing tumor activity before and after, they found that the extract significantly slowed the tumors' growth, suggesting its potential as a natural anti-cancer treatment. This is promising early evidence, but further research is needed to confirm its long-term effects and potential side effects.
Boswellia #Frankincense #cancer
Valente, I.V.B., Garcia, D., Abbott, A. et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat (2024). https://doi.org/10.1007/s10549-023-07215-4
Boswellia, frankincense, breast cancer, tumor growth, clinical trial, MUSC Hollings Cancer Center, natural cancer treatment, alternative medicine, cancer research, breakthrough, promising results, early study, reduce tumor size, slow cancer growth, inhibit cancer cells, proliferation, apoptosis, safe and well-tolerated, Phase Ia window of opportunity trial, oral administration, 2400mg daily, human study, in vivo, in vitro
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Researchers gave breast cancer patients an extract from the Boswellia tree (aka frankincense) daily before surgery. Comparing tumor activity before and after, they found that the extract significantly slowed the tumors' growth, suggesting its potential as a natural anti-cancer treatment. This is promising early evidence, but further research is needed to confirm its long-term effects and potential side effects.
Boswellia #Frankincense #cancer
Valente, I.V.B., Garcia, D., Abbott, A. et al. The anti-proliferative effects of a frankincense extract in a window of opportunity phase ia clinical trial for patients with breast cancer. Breast Cancer Res Treat (2024). https://doi.org/10.1007/s10549-023-07215-4
Boswellia, frankincense, breast cancer, tumor growth, clinical trial, MUSC Hollings Cancer Center, natural cancer treatment, alternative medicine, cancer research, breakthrough, promising results, early study, reduce tumor size, slow cancer growth, inhibit cancer cells, proliferation, apoptosis, safe and well-tolerated, Phase Ia window of opportunity trial, oral administration, 2400mg daily, human study, in vivo, in vitro
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A single dose of mangiferin-quercetin, taken one hour before exercise, significantly improved participants' performance in a demanding physical test. They completed circuits faster and reported feeling less exertion compared to those given a placebo. This suggests the supplement could enhance overall exercise performance by boosting endurance and reducing fatigue. Further studies are needed to confirm these findings in different exercise types and populations.
NaturalEnergyFuel #BreakThroughFatigue #alchepharma
Alchepharma,Ralph Turchiano,citation,research,study,Mangiferin,Quercetin,mango,Mangifera indica,exercise performance,single dose,muscle oxygen extraction,basketball simulation,circuit time,perceived exertion,endurance,fatigue,athletes,natural supplement,pre-workout,recovery,brain oxygenation,oxygen extraction,high-intensity exercise,non-athletes,double-blind study,randomized controlled trial,sports performance,athletic performance,exercise science
Bourdas, D. I., Travlos, A. K., Souglis, A., Stavropoulou, G., Zacharakis, E., Gofas, D. C., & Bakirtzoglou, P. (2024). Effects of a Singular Dose of Mangiferin–Quercetin Supplementation on Basketball Performance: A Double-Blind Crossover Study of High-Level Male Players. Nutrients, 16(1), 170. https://doi.org/10.3390/nu16010170
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A single dose of mangiferin-quercetin, taken one hour before exercise, significantly improved participants' performance in a demanding physical test. They completed circuits faster and reported feeling less exertion compared to those given a placebo. This suggests the supplement could enhance overall exercise performance by boosting endurance and reducing fatigue. Further studies are needed to confirm these findings in different exercise types and populations.
NaturalEnergyFuel #BreakThroughFatigue #alchepharma
Alchepharma,Ralph Turchiano, citation,research,study,Mangiferin,Quercetin,mango,Mangifera indica,exercise performance,single dose,muscle oxygen extraction,basketball simulation,circuit time,perceived exertion,endurance,fatigue,athletes,natural supplement,pre-workout,recovery,brain oxygenation,oxygen extraction,high-intensity exercise,non-athletes,double-blind study,randomized controlled trial,sports performance,athletic performance,exercise science
Bourdas, D. I., Travlos, A. K., Souglis, A., Stavropoulou, G., Zacharakis, E., Gofas, D. C., & Bakirtzoglou, P. (2024). Effects of a Singular Dose of Mangiferin–Quercetin Supplementation on Basketball Performance: A Double-Blind Crossover Study of High-Level Male Players. Nutrients, 16(1), 170. https://doi.org/10.3390/nu16010170
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A new study suggests that simply swapping one serving of starchy carbohydrates for vegetables daily can significantly improve fatty liver disease (NAFLD), even in advanced stages. Researchers found that after just three months, this minor dietary change led to reductions in liver fibrosis, inflammation, and other NAFLD markers. The key seems to be the type of vegetables chosen: the study focused on four cruciferous varieties (mizuna, chicory, kale, and Chinese mustard) rich in glucobrassicin-derived compounds with antioxidant and anti-fatty liver properties. This easy-to-implement dietary tweak could offer a promising first step for managing and potentially reversing NAFLD.
NAFLD #diet #fattyliver
De Nucci S, Rinaldi R, Di Chito M, Donghia R, Giannuzzi V, Shahini E, Cozzolongo R, Pesole PL, Coletta S, De Pergola G, et al. The Replacement of Only One Portion of Starchy Carbohydrates with Green Leafy Vegetables Regresses Mid and Advanced Stages of NAFLD: Results from a Prospective Pilot Study. Nutrients. 2023; 15(10):2289. https://doi.org/10.3390/nu15102289
NAFLD,fatty liver diet,natural remedies,reversal,diet changes,liver health,cruciferous veggies,glucobrassicin,one serving change,mid advanced NAFLD,pilot study,replace carbs greens,leafy greens fatty liver,3 month diet challenge,fibrosis reduction swaps,manage reverse
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This report investigates purple corn extract (PCE) as a potential natural remedy for dry eye disease (DED). Studies show PCE possesses antioxidant and anti-inflammatory properties, suggesting its ability to protect against DED's damaging effects. Oral PCE administration in animal models significantly improved tear production, corneal health, and goblet cell density, demonstrating its effectiveness in treating DED symptoms. These findings suggest PCE can be a safe and effective functional food for promoting eye health, particularly in DED cases, offering a promising alternative to conventional treatments.
Anthocyanin #PurpleCorn #Dryeyes
Lee J-M, Choi A, Lee H-H, Park SJ, Kim B-H. Purple Corn Extract Improves Dry Eye Symptoms in Models Induced by Desiccating Stress and Extraorbital Lacrimal Gland Excision. Nutrients. 2023; 15(24):5063. https://doi.org/10.3390/nu15245063
DryEye, PurpleCornExtract, Anthocyanins, TearsOfJoy, NaturalRemedy, GobletCells, InflammationRelief, Omega3Comparison, EyeHealthFood, FutureOfEyeCare, DryEyeModels, DesiccationStress, LacrimalGlandExcision, #DryEye #PurpleCorn #EyeCare #NaturalHealth
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This report investigates purple corn extract (PCE) as a potential natural remedy for dry eye disease (DED). Studies show PCE possesses antioxidant and anti-inflammatory properties, suggesting its ability to protect against DED's damaging effects. Oral PCE administration in animal models significantly improved tear production, corneal health, and goblet cell density, demonstrating its effectiveness in treating DED symptoms. These findings suggest PCE can be a safe and effective functional food for promoting eye health, particularly in DED cases, offering a promising alternative to conventional treatments.
Anthocyanin #PurpleCorn #Dryeyes
Lee J-M, Choi A, Lee H-H, Park SJ, Kim B-H. Purple Corn Extract Improves Dry Eye Symptoms in Models Induced by Desiccating Stress and Extraorbital Lacrimal Gland Excision. Nutrients. 2023; 15(24):5063. https://doi.org/10.3390/nu15245063
DryEye, PurpleCornExtract, Anthocyanins, TearsOfJoy, NaturalRemedy, GobletCells, InflammationRelief, Omega3Comparison, EyeHealthFood, FutureOfEyeCare, DryEyeModels, DesiccationStress, LacrimalGlandExcision, #DryEye #PurpleCorn #EyeCare #NaturalHealth
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This report investigates purple corn extract (PCE) as a potential natural remedy for dry eye disease (DED). Studies show PCE possesses antioxidant and anti-inflammatory properties, suggesting its ability to protect against DED's damaging effects. Oral PCE administration in animal models significantly improved tear production, corneal health, and goblet cell density, demonstrating its effectiveness in treating DED symptoms. These findings suggest PCE can be a safe and effective functional food for promoting eye health, particularly in DED cases, offering a promising alternative to conventional treatments.
Anthocyanin #PurpleCorn #Dryeyes
Lee J-M, Choi A, Lee H-H, Park SJ, Kim B-H. Purple Corn Extract Improves Dry Eye Symptoms in Models Induced by Desiccating Stress and Extraorbital Lacrimal Gland Excision. Nutrients. 2023; 15(24):5063. https://doi.org/10.3390/nu15245063
DryEye, PurpleCornExtract, Anthocyanins, TearsOfJoy, NaturalRemedy, GobletCells, InflammationRelief, Omega3Comparison, EyeHealthFood, FutureOfEyeCare, DryEyeModels, DesiccationStress, LacrimalGlandExcision, #DryEye #PurpleCorn #EyeCare #NaturalHealth
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Purple Corn: A Delicious Solution to Dry Eye Discomfort Ep. 1168 DEC 2023
This report investigates purple corn extract (PCE) as a potential natural remedy for dry eye disease (DED). Studies show PCE possesses antioxidant and anti-inflammatory properties, suggesting its ability to protect against DED's damaging effects. Oral PCE administration in animal models significantly improved tear production, corneal health, and goblet cell density, demonstrating its effectiveness in treating DED symptoms. These findings suggest PCE can be a safe and effective functional food for promoting eye health, particularly in DED cases, offering a promising alternative to conventional treatments.
Anthocyanin #PurpleCorn #Dryeyes
Lee J-M, Choi A, Lee H-H, Park SJ, Kim B-H. Purple Corn Extract Improves Dry Eye Symptoms in Models Induced by Desiccating Stress and Extraorbital Lacrimal Gland Excision. Nutrients. 2023; 15(24):5063. https://doi.org/10.3390/nu15245063
DryEye, PurpleCornExtract, Anthocyanins, TearsOfJoy, NaturalRemedy, GobletCells, InflammationRelief, Omega3Comparison, EyeHealthFood, FutureOfEyeCare, DryEyeModels, DesiccationStress, LacrimalGlandExcision, #DryEye #PurpleCorn #EyeCare #NaturalHealth
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A new study suggests that simply swapping one serving of starchy carbohydrates for vegetables daily can significantly improve fatty liver disease (NAFLD), even in advanced stages. Researchers found that after just three months, this minor dietary change led to reductions in liver fibrosis, inflammation, and other NAFLD markers. The key seems to be the type of vegetables chosen: the study focused on four cruciferous varieties (mizuna, chicory, kale, and Chinese mustard) rich in glucobrassicin-derived compounds with antioxidant and anti-fatty liver properties. This easy-to-implement dietary tweak could offer a promising first step for managing and potentially reversing NAFLD.
NAFLD #diet #fattyliver
De Nucci S, Rinaldi R, Di Chito M, Donghia R, Giannuzzi V, Shahini E, Cozzolongo R, Pesole PL, Coletta S, De Pergola G, et al. The Replacement of Only One Portion of Starchy Carbohydrates with Green Leafy Vegetables Regresses Mid and Advanced Stages of NAFLD: Results from a Prospective Pilot Study. Nutrients. 2023; 15(10):2289. https://doi.org/10.3390/nu15102289
NAFLD,fatty liver diet,natural remedies,reversal,diet changes,liver health,cruciferous veggies,glucobrassicin,one serving change,mid advanced NAFLD,pilot study,replace carbs greens,leafy greens fatty liver,3 month diet challenge,fibrosis reduction swaps,manage reverse
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This study investigated the effects of consuming a combination of Bifidobacterium animalis subsp. lactis GCL2505 and inulin on abdominal fat reduction. The results showed that participants who consumed the combined beverage had significant reductions in visceral fat area and total fat area compared to the placebo group. Additionally, the intervention increased the total number of bifidobacteria in the gut and affected several lipid markers. The authors suggest that the combined intake of GCL2505 and inulin improves the intestinal environment and reduces abdominal fat through a mechanism involving short-chain fatty acids (SCFAs). Further research is needed to investigate the full mechanisms involved in this effect. Overall, the study suggests that the combined intake of GCL2505 and inulin may be a simple and effective way to reduce abdominal fat and potentially prevent metabolic abnormalities.
probiotics #weightloss #BMI
Baba Y, Saito Y, Kadowaki M, Azuma N, Tsuge D. Effect of Continuous Ingestion of Bifidobacteria and Inulin on Reducing Body Fat: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study. Nutrients. 2023; 15(24):5025. https://doi.org/10.3390/nu15245025
visceral fat reduction, inulin and bifidobacteria, GCL2505 probiotic, gut health and weight loss, natural ways to reduce abdominal fat, reducing inflammation through diet, probiotics for metabolic health, improving digestion and gut microbiome, "GCL2505 and inulin combined", "Bifidobacterium animalis subsp. lactis GCL2505 study",
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Synbiotic drink result in important Fat Loss Ep. 1167 DEC 2023
This study investigated the effects of consuming a combination of Bifidobacterium animalis subsp. lactis GCL2505 and inulin on abdominal fat reduction. The results showed that participants who consumed the combined beverage had significant reductions in visceral fat area and total fat area compared to the placebo group. Additionally, the intervention increased the total number of bifidobacteria in the gut and affected several lipid markers. The authors suggest that the combined intake of GCL2505 and inulin improves the intestinal environment and reduces abdominal fat through a mechanism involving short-chain fatty acids (SCFAs). Further research is needed to investigate the full mechanisms involved in this effect. Overall, the study suggests that the combined intake of GCL2505 and inulin may be a simple and effective way to reduce abdominal fat and potentially prevent metabolic abnormalities.
probiotics #weightloss #BMI
Baba Y, Saito Y, Kadowaki M, Azuma N, Tsuge D. Effect of Continuous Ingestion of Bifidobacteria and Inulin on Reducing Body Fat: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Study. Nutrients. 2023; 15(24):5025. https://doi.org/10.3390/nu15245025
visceral fat reduction, inulin and bifidobacteria, GCL2505 probiotic, gut health and weight loss, natural ways to reduce abdominal fat, reducing inflammation through diet, probiotics for metabolic health, improving digestion and gut microbiome, "GCL2505 and inulin combined", "Bifidobacterium animalis subsp. lactis GCL2505 study",
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A new study by Johns Hopkins Medicine suggests that epigallocatechin gallate (EGCG), a compound found in green tea, could be a promising treatment for uterine fibroids. The study found that EGCG reduced the protein levels of fibronectin, a protein involved in fibroid growth, by up to 52%. Additionally, EGCG disrupted pathways involved in fibroid tumor cell growth, movement, signaling and metabolism. These results suggest that EGCG may be an effective way to treat and prevent uterine fibroids.#EGCG #GreenTea #fibroidtreatment Islam, M. S., Parish, M., Brennan, J. T., Winer, B. L., & Segars, J. H. (2023). Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids. Scientific Reports, 13(1), 1-13. https://doi.org/10.1038/s41598-023-35212-6EGCG for uterine fibroids, Green tea extract for fibroids, Natural treatment for uterine fibroids, Alternative therapy for fibroids, Uterine fibroid research, Shrinking uterine fibroids, Johns Hopkins fibroid study, EGCG and fibroid growth, Fibroid cell study, Fibroid signaling pathways, EGCG mechanism of action, Uterine fibroid treatment options, FRIEND clinical trial, EGCG dosage for fibroids, EGCG side effects, Green tea and fibroids, Uterine fibroid symptoms, Uterine fibroid causes, EGCG+fibroids, Green tea extract+uterine fibroids, Fibroid treatment+natural, Johns Hopkins+EGCG+fibroids,
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A new study by Johns Hopkins Medicine suggests that epigallocatechin gallate (EGCG), a compound found in green tea, could be a promising treatment for uterine fibroids. The study found that EGCG reduced the protein levels of fibronectin, a protein involved in fibroid growth, by up to 52%. Additionally, EGCG disrupted pathways involved in fibroid tumor cell growth, movement, signaling and metabolism. These results suggest that EGCG may be an effective way to treat and prevent uterine fibroids.#EGCG #GreenTea #fibroidtreatment Islam, M. S., Parish, M., Brennan, J. T., Winer, B. L., & Segars, J. H. (2023). Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids. Scientific Reports, 13(1), 1-13. https://doi.org/10.1038/s41598-023-35212-6EGCG for uterine fibroids, Green tea extract for fibroids, Natural treatment for uterine fibroids, Alternative therapy for fibroids, Uterine fibroid research, Shrinking uterine fibroids, Johns Hopkins fibroid study, EGCG and fibroid growth, Fibroid cell study, Fibroid signaling pathways, EGCG mechanism of action, Uterine fibroid treatment options, FRIEND clinical trial, EGCG dosage for fibroids, EGCG side effects, Green tea and fibroids, Uterine fibroid symptoms, Uterine fibroid causes, EGCG+fibroids, Green tea extract+uterine fibroids, Fibroid treatment+natural, Johns Hopkins+EGCG+fibroids,
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This trial examined the effects of H. erinaceus on cognitive function and mood in young adults. Participants took a single 1.8 g dose of H. erinaceus and then supplemented for 28 days. Results showed faster performance on the Stroop task with a single dose and a potential stress-reducing effect with supplementation.#lionsmanemushroom #brainhealth #stressrelief Docherty, S., Doughty, F. L., & Smith, E. F. (2023). The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients, 15(22), 4842. https://doi.org/10.3390/nu15224842Hericium erinaceus , lions mane benefits, lions mane mushroom for anxiety, lions mane mushroom for depression, lions mane mushroom for cognitive function, lions mane mushroom for focus, lions mane mushroom for memory, lions mane mushroom for nerve health, lions mane mushroom for pain, lions mane mushroom for inflammation, lions mane mushroom for cancer, lions mane mushroom dosage, lions mane mushroom side effects, lions mane mushroom recipes, lions mane mushroom powder, lions mane mushroom extract, lions mane mushroom supplements
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This trial examined the effects of H. erinaceus on cognitive function and mood in young adults. Participants took a single 1.8 g dose of H. erinaceus and then supplemented for 28 days. Results showed faster performance on the Stroop task with a single dose and a potential stress-reducing effect with supplementation.#lionsmanemushroom #brainhealth #stressrelief Docherty, S., Doughty, F. L., & Smith, E. F. (2023). The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study. Nutrients, 15(22), 4842. https://doi.org/10.3390/nu15224842Hericium erinaceus , lions mane benefits, lions mane mushroom for anxiety, lions mane mushroom for depression, lions mane mushroom for cognitive function, lions mane mushroom for focus, lions mane mushroom for memory, lions mane mushroom for nerve health, lions mane mushroom for pain, lions mane mushroom for inflammation, lions mane mushroom for cancer, lions mane mushroom dosage, lions mane mushroom side effects, lions mane mushroom recipes, lions mane mushroom powder, lions mane mushroom extract, lions mane mushroom supplements
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The Physicians Committee for Responsible Medicine has conducted a study that shows a low-fat vegan diet, which includes soy, can significantly reduce postmenopausal vasomotor symptoms, commonly known as hot flashes. The study observed a 95% decrease in hot flashes overall, while severe hot flashes were completely eliminated. Moderate-to-severe hot flashes decreased by 96%, and daytime and nighttime hot flashes reduced by 96% and 94%, respectively. In addition, participants on the vegan diet lost an average of 6.4 pounds.#MenopauseRelief #HotFlashes #nightsweats Kahleova, H., Holtz, D. N., Strom, N., La Reau, A., Kolipaka, S., Schmidt, N., Hata, E., Znayenko-Miller, T., Holubkov, R., & Barnard, N. D. (2023). A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis. Complementary Therapies in Medicine, 79, 103002. https://doi.org/10.1016/j.ctim.2023.103002Vegan diet, gut microbiome, hot flashes, low-fat vegan diet, menopause, soybeans, plant-based diet, menopausal symptoms, WAVS trial, Physicians Committee for Responsible Medicine, postmenopausal vasomotor symptoms, moderate-to-severe hot flashes, Fusicatenibacter, Holdemanella
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The Physicians Committee for Responsible Medicine has conducted a study that shows a low-fat vegan diet, which includes soy, can significantly reduce postmenopausal vasomotor symptoms, commonly known as hot flashes. The study observed a 95% decrease in hot flashes overall, while severe hot flashes were completely eliminated. Moderate-to-severe hot flashes decreased by 96%, and daytime and nighttime hot flashes reduced by 96% and 94%, respectively. In addition, participants on the vegan diet lost an average of 6.4 pounds.
MenopauseRelief #HotFlashes #nightsweats
Kahleova, H., Holtz, D. N., Strom, N., La Reau, A., Kolipaka, S., Schmidt, N., Hata, E., Znayenko-Miller, T., Holubkov, R., & Barnard, N. D. (2023). A dietary intervention for postmenopausal hot flashes: A potential role of gut microbiome. An exploratory analysis. Complementary Therapies in Medicine, 79, 103002. https://doi.org/10.1016/j.ctim.2023.103002
Vegan diet, gut microbiome, hot flashes, low-fat vegan diet, menopause, soybeans, plant-based diet, menopausal symptoms, WAVS trial, Physicians Committee for Responsible Medicine, postmenopausal vasomotor symptoms, moderate-to-severe hot flashes, Fusicatenibacter, Holdemanella
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Study shows intermittent fasting helps Type 2 diabeticsmanage weight and blood sugar levels. Participants who ate within an 8-hourwindow lost more weight in 6 months than those who reduced calorie intake by25%. No adverse events or blood sugar issues reported.
TRE #timerestrictedeating #diabetes
Pavlou V, Cienfuegos S, Lin S, et al. Effect ofTime-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: ARandomized Clinical Trial. JAMA Netw Open. 2023;6(10):e2339337.doi:10.1001/jamanetworkopen.2023.39337
Alchepharma,RalphTurchiano,citation,research,study,time-restricted eating,type 2diabetes,intermittent fasting,type 2 diabetes diet breakthrough,reversediabetes with time-restricted eating,time-restricted eating weight lossresults,time-restricted eating blood sugar control,time-restricted eatingsafety,intermittent fasting for beginners,time-restricted eating tips andtricks,intermittent fasting for weight loss,8-hour time-restricted eating fortype 2 diabetes
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Study shows intermittent fasting helps Type 2 diabetics manage weight and blood sugar levels. Participants who ate within an 8-hour window lost more weight in 6 months than those who reduced calorie intake by 25%. No adverse events or blood sugar issues reported.
TRE #timerestrictedeating #diabetes
Pavlou V, Cienfuegos S, Lin S, et al. Effect of Time-Restricted Eating on Weight Loss in Adults With Type 2 Diabetes: A Randomized Clinical Trial. JAMA Netw Open. 2023;6(10):e2339337. doi:10.1001/jamanetworkopen.2023.39337
Alchepharma,Ralph Turchiano,citation,research,study,time-restricted eating,type 2 diabetes,intermittent fasting,type 2 diabetes diet breakthrough,reverse diabetes with time-restricted eating,time-restricted eating weight loss results,time-restricted eating blood sugar control,time-restricted eating safety,intermittent fasting for beginners,time-restricted eating tips and tricks,intermittent fasting for weight loss,8-hour time-restricted eating for type 2 diabetes
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New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) formation, also known as NETosis, and what it may mean for controlling inflammation.
ginger #autoimmune #gingerol
Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, M. Kristen Demoruelle. Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans. JCI Insight, 2023; 8 (18) DOI: 10.1172/jci.insight.172011
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Ginger consumption and possible autoimmune benefits Ep. 1162 NOV 2023
New research has revealed a potentially important role ginger supplements can play in controlling inflammation for people living with autoimmune diseases. The research focused on studying the impact of ginger supplementation on a type of white blood cell called the neutrophil. The study was especially interested in neutrophil extracellular trap (NET) formation, also known as NETosis, and what it may mean for controlling inflammation.
ginger #autoimmune #gingerol
Ramadan A. Ali, Valerie C. Minarchick, Miela Zahavi, Christine E. Rysenga, Kristin A. Sturm, Claire K. Hoy, Cyrus Sarosh, Jason S. Knight, M. Kristen Demoruelle. Ginger intake suppresses neutrophil extracellular trap formation in autoimmune mice and healthy humans. JCI Insight, 2023; 8 (18) DOI: 10.1172/jci.insight.172011
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Establishing the relationship between inflammatory markers like IL-6 and CRP [and vitamin B12 levels] could have direct clinical relevance and open doors to novel therapeutic strategies.
B12 #Inflammation #Homocysteine
Domínguez-López, I., Kovatcheva, M., Casas, R., Toledo, E., Fitó, M., Ros, E., Estruch, R., Serrano, M., & Lamuela-Raventós, R. M. Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.12976
B12, Homocysteine, Inflammation, interlukin-6, CRP, IL-6 C reactive protein, diabetes, cancer, atherosclerosis, B12 deficiency
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Establishing the relationship between inflammatory markers like IL-6 and CRP [and vitamin B12 levels] could have direct clinical relevance and open doors to novel therapeutic strategies.’
B12 #Inflammation #Homocysteine
Domínguez-López, I., Kovatcheva, M., Casas, R., Toledo, E., Fitó, M., Ros, E., Estruch, R., Serrano, M., & Lamuela-Raventós, R. M. Higher circulating vitamin B12 is associated with lower levels of inflammatory markers in individuals at high cardiovascular risk and in naturally aged mice. Journal of the Science of Food and Agriculture. https://doi.org/10.1002/jsfa.12976
B12, Homocysteine, Inflammation, interlukin-6, CRP, IL-6 C reactive protein, diabetes, cancer, atherosclerosis, B12 deficiency
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It can increase the rate of protein synthesis within muscle cells and inhibit protein degradation processes [53]. This allows muscle cells to more effectively synthesize new proteins and maintain muscle mass. Additionally, Urolithin A can improve muscle endurance and exercise performance by promoting mitochondrial function and muscle energy metabolism [66]. This may lead to longer and more intense training sessions, further promoting muscle hypertrophy and the maintenance of muscle mass.
urolitinA #strength #endurance
Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., Xie, Y., & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441. https://doi.org/10.3390/nu15204441
Urolithin a, Ellagitannins, muscle mass, strength, speed, endurance, energy, contraction speed, atp, Enhanced Muscle Function, Delaying Muscle Fatigue, Muscle Atrophy, Antioxidant Defense, Mitochondrial Dysfunction, Inflammatory Conditions, Oxidative Stress,
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It can increase the rate of protein synthesis within muscle cells and inhibit protein degradation processes [53]. This allows muscle cells to more effectively synthesize new proteins and maintain muscle mass. Additionally, Urolithin A can improve muscle endurance and exercise performance by promoting mitochondrial function and muscle energy metabolism [66]. This may lead to longer and more intense training sessions, further promoting muscle hypertrophy and the maintenance of muscle mass.
urolitinA #strength #endurance
Zhao, H., Song, G., Zhu, H., Qian, H., Pan, X., Song, X., Xie, Y., & Liu, C. (2023). Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects. Nutrients, 15(20), 4441. https://doi.org/10.3390/nu15204441
Urolithin a, Ellagitannins, muscle mass, strength, speed, endurance, energy, contraction speed, atp, Enhanced Muscle Function, Delaying Muscle Fatigue, Muscle Atrophy, Antioxidant Defense, Mitochondrial Dysfunction, Inflammatory Conditions, Oxidative Stress,
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Choline may affect muscle responses to RET through many potential mechanisms. Since choline is a precursor to a neurotransmitter, ACh, which relays a signal from motor neurons to skeletal muscle to contract and generate force, and of which synthesis is reported to be affected by availability of choline [36,37], insufficient choline consumption may limit the availability of ACh at the neuromuscular junction (NMJ) and, in turn, muscle contraction and force generation.
choline #strength #muscle
Lee, C. W., Lee, T. V., Galvan, E., Chen, V. C., Bui, S., Crouse, S. F., Fluckey, J. D., Smith, S. B., & Riechman, S. E. (2023). The Effect of Choline and Resistance Training on Strength and Lean Mass in Older Adults. Nutrients, 15(18), 3874. https://doi.org/10.3390/nu15183874
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Choline may affect muscle responses to RET through many potential mechanisms. Since choline is a precursor to a neurotransmitter, ACh, which relays a signal from motor neurons to skeletal muscle to contract and generate force, and of which synthesis is reported to be affected by availability of choline [36,37], insufficient choline consumption may limit the availability of ACh at the neuromuscular junction (NMJ) and, in turn, muscle contraction and force generation.
choline #strength #muscle
Lee, C. W.,Lee, T. V., Galvan, E., Chen, V. C., Bui, S., Crouse, S. F., Fluckey, J. D.,Smith, S. B., & Riechman, S. E. (2023). The Effect of Choline and Resistance Training on Strength and Lean Mass in Older Adults. Nutrients, 15(18), 3874. https://doi.org/10.3390/nu15183874
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Dark tea may Dramatically HELP control blood sugar to reduce diabetes risk Episode 1158 OCT 2023
The study, by researchers from the University of Adelaide in Australia and Southeast University in China, found that compared with never tea drinkers, daily consumers (never, occasionally, often and every day) ) of dark tea had 53% lower risk for prediabetes and 47% reduced risk for type 2 diabetes, even after taking into account established risk factors known to drive the risk for diabetes, including age, gender, ethnicity, body mass index (BMI), average arterial blood pressure, fasting plasma glucose, cholesterol, alcohol intake, smoking status, family history of diabetes and regular exercise.
darktea #bloodsugar #diabetes
Poster presentation 329 at the annual meeting of the European Association for the Study of Diabetes (EASD), Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults T. Li, M. Sang, J. Wang, Z. Sun, C. Xie, C. Rayner, M. Horowitz, S. Qiu, T. Wu, Australia, China
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The study, by researchers from the University of Adelaide in Australia and Southeast University in China, found that compared with never tea drinkers, daily consumers (never, occasionally, often and every day) ) of dark tea had 53% lower risk for prediabetes and 47% reduced risk for type 2 diabetes, even after taking into account established risk factors known to drive the risk for diabetes, including age, gender, ethnicity, body mass index (BMI), average arterial blood pressure, fasting plasma glucose, cholesterol, alcohol intake, smoking status, family history of diabetes and regular exercise.
darktea #bloodsugar #diabetes
Poster presentation 329 at the annual meeting of the European Association for the Study of Diabetes (EASD), Tea consumption is associated with increased urinary glucose excretion, improved insulin resistance and reduced risk of dysglycaemia, in Chinese community-dwelling adults T. Li, M. Sang, J. Wang, Z. Sun, C. Xie, C. Rayner, M. Horowitz, S. Qiu, T. Wu, Australia, China
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Recent studies have reported the beneficial effects of KRG extract— a traditional herbal medicine— in treating neuroinflammation. Although, it has been traditionally used to treat a number of ailments, KRG is now finding use in diseases of the modern day, such as cardiovascular diseases, cancer, and Alzheimer’s disease. Previous research on rodents has demonstrated that KRG can relieve addiction against psychoactive agents. However, not much is known about the its effects on alcohol-induced addictive responses and cognitive impariment.
koreanredginseng #addiction #neuroinflammation
Kim, H. J., Lee, M. Y., Kim, G. R., Lee, H. J., Sayson, L. V., Ortiz, D. M. D., Cheong, J. H., & Kim, M. (2023). Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation. Journal of Ginseng Research, 47(4), 583-592. https://doi.org/10.1016/j.jgr.2023.02.003
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Recent studies have reported the beneficial effects of KRG extract— a traditional herbal medicine— in treating neuroinflammation. Although, it has been traditionally used to treat a number of ailments, KRG is now finding use in diseases of the modern day, such as cardiovascular diseases, cancer, and Alzheimer’s disease. Previous research on rodents has demonstrated that KRG can relieve addiction against psychoactive agents. However, not much is known about the its effects on alcohol-induced addictive responses and cognitive impariment.
koreanredginseng #addiction #neuroinflammation
Kim, H. J., Lee, M. Y., Kim, G. R., Lee, H. J., Sayson, L. V., Ortiz, D. M. D., Cheong, J. H., & Kim, M. (2023). Korean Red Ginseng extract attenuates alcohol-induced addictive responses and cognitive impairments by alleviating neuroinflammation. Journal of Ginseng Research, 47(4), 583-592. https://doi.org/10.1016/j.jgr.2023.02.003
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Implications for the Future- In essence, this groundbreaking research indicates that by encouraging the recycling of mitochondria using Urolithin A, it is possible to reverse the aging process within the hematopoietic and immune systems. These findings hold immense promise for the development of interventions targeted at addressing age-related health conditions in older individuals and pave the way for envisioning clinical trials.
urolithinA #ellagic #ellagitannins
Girotra, M., Chiang, Y., Charmoy, M., Ginefra, P., Hope, H. C., Bataclan, C., Yu, Y., Schyrr, F., Franco, F., Geiger, H., Cherix, S., Ho, P., Naveiras, O., Auwerx, J., Held, W., & Vannini, N. (2023). Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems. Nature Aging, 1-10. https://doi.org/10.1038/s43587-023-00473-3
An, L., Lu, Q., Wang, K., & Wang, Y. (2023). Urolithins: A Prospective Alternative against Brain Aging. Nutrients, 15(18), 3884. https://doi.org/10.3390/nu15183884
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Implicationsfor the Future- In essence, this groundbreaking research indicates that byencouraging the recycling of mitochondria using Urolithin A, it is possible toreverse the aging process within the hematopoietic and immune systems. Thesefindings hold immense promise for the development of interventions targeted ataddressing age-related health conditions in older individuals and pave the wayfor envisioning clinical trials.
urolithinA#ellagic #ellagitannins
Girotra, M.,Chiang, Y., Charmoy, M., Ginefra, P., Hope, H. C., Bataclan, C., Yu, Y.,Schyrr, F., Franco, F., Geiger, H., Cherix, S., Ho, P., Naveiras, O., Auwerx,J., Held, W., & Vannini, N. (2023). Induction of mitochondrial recyclingreverts age-associated decline of the hematopoietic and immune systems. NatureAging, 1-10. https://doi.org/10.1038/s43587-023-00473-3
An, L., Lu,Q., Wang, K., & Wang, Y. (2023). Urolithins: A Prospective Alternativeagainst Brain Aging. Nutrients, 15(18), 3884. https://doi.org/10.3390/nu15183884
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Peppermint Oil Endurance Booster
Peppermint essential oil, with its active ingredients, isbelieved to reduce oxidative stress and inflammation induced by exercise andthus relieve exercise-induced fatigue and improve exercise performance
peppermint #endurance #exercise
Zhang, W., Shi, R., Gao, T., Hu, Y., Zhou, J., Li, C., Wang,P., Yang, H., Xing, W., Dong, L., & Gao, F. (2023). Repeated Inhalation ofPeppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats.Nutrients, 15(11), 2480. https://doi.org/10.3390/nu15112480
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Peppermint essential oil, with its active ingredients, isbelieved to reduce oxidative stress and inflammation induced by exercise andthus relieve exercise-induced fatigue and improve exercise performance
peppermint #endurance #exercise
Zhang, W., Shi, R., Gao, T., Hu, Y., Zhou, J., Li, C., Wang,P., Yang, H., Xing, W., Dong, L., & Gao, F. (2023). Repeated Inhalation ofPeppermint Essential Oil Improves Exercise Performance in Endurance-Trained Rats.Nutrients, 15(11), 2480. https://doi.org/10.3390/nu15112480
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The active ingredients of ginseng mainly contribute to aging delay through the following mechanisms: (1) the increase in the expression of antioxidant enzymes to achieve a balance between intracellular oxidation and antioxidation, the mitigation of excessive production of ROS, and the reduction in endogenous DNA damage, which prevent cell cycle arrest and delay aging; and (2) the regulation of the activities of DNA glycosylase and sirtuins in the process of DNA damage repair to ensure that the DNA repair pathway can accurately repair DNA damage caused by various factors associated with aging.
ginseng #aging #microbiota
Su, J., Su, Q., Hu, S., Ruan, X., & Ouyang, S. (2023). Research Progress on the Anti-Aging Potential of the Active Components of Ginseng. Nutrients, 15(15), 3286. https://doi.org/10.3390/nu15153286
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The active ingredients of ginseng mainly contribute to aging delay through the following mechanisms: (1) the increase in the expression of antioxidant enzymes to achieve a balance between intracellular oxidation and antioxidation, the mitigation of excessive production of ROS, and the reduction in endogenous DNA damage, which prevent cell cycle arrest and delay aging; and (2) the regulation of the activities of DNA glycosylase and sirtuins in the process of DNA damage repair to ensure that the DNA repair pathway can accurately repair DNA damage caused by various factors associated with aging.
ginseng #aging #microbiota
Su, J., Su, Q., Hu, S., Ruan, X., & Ouyang, S. (2023). Research Progress on the Anti-Aging Potential of the Active Components of Ginseng. Nutrients, 15(15), 3286. https://doi.org/10.3390/nu15153286
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226% increase in Cognition with Essential Oils Show 1150 AUG 2023
When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia.
cognition #aromatherapy #olfactory
Woo, C. C., Miranda, B., Sathishkumar, M., Yassa, M. A., & Leon, M. (2023). Overnight olfactory enrichment using an odorant diffuser improves memory and modifies the uncinate fasciculus in older adults. Frontiers in Neuroscience, 17, 1200448. https://doi.org/10.3389/fnins.2023.1200448
Cognition, memory, scent, essential oils, verbal learning, dementia, aromatherapy , uncinate fasciculus, rose, orange, eucalyptus, lemon, peppermint, rosemary, lavender, gray matter, white matter, olfactory enrichment, olfactory stimulation, olfactory ability, Alzheimer’s
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226% increase in Cognition with Essential Oils Show 1150 AUG 2023
When a fragrance wafted through the bedrooms of older adults for two hours every night for six months, memories skyrocketed. Participants in this study by University of California, Irvine neuroscientists reaped a 226% increase in cognitive capacity compared to the control group. The researchers say the finding transforms the long-known tie between smell and memory into an easy, non-invasive technique for strengthening memory and potentially deterring dementia.
cognition #aromatherapy #olfactory
Woo, C. C., Miranda, B., Sathishkumar, M., Yassa, M. A., & Leon, M. (2023). Overnight olfactory enrichment using an odorant diffuser improves memory and modifies the uncinate fasciculus in older adults. Frontiers in Neuroscience, 17, 1200448. https://doi.org/10.3389/fnins.2023.1200448
Cognition, memory, scent, essential oils, verbal learning, dementia, aromatherapy , uncinate fasciculus, rose, orange, eucalyptus, lemon, peppermint, rosemary, lavender, gray matter, white matter, olfactory enrichment, olfactory stimulation, olfactory ability, Alzheimer’s
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Muscadine shows great promise in improving aging skin. Show 1149 AUG 2023
Researchers measured participants’ skin conditions and markers of inflammation and oxidative stress at the start of the study and at the end of each six-week period. They found that drinking muscadine wine significantly improved skin elasticity (a loss of elasticity is what causes skin to sag more as we age). In addition, the wine was associated with a decrease in water loss at the skin surface, a measurement that indicates the skin is providing a more effective barrier against damage.
skin #skinhealth #skinage
(P23-018-23) Dealcoholized Muscadine Wine Improved Skin Health, Reduced Oxidative Stress and Inflammation in Women in a Randomized Controlled Trial
Skin, muscadine, skin elasticity, viscoelasticity, anti wrinkle, skin moisture, polyphenols, inflammation. Oxidative stress, anti aging, youthing, healthy skin,
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Muscadine shows great promise in improving aging skin. Show 1149 AUG 2023
Researchers measured participants’ skin conditions and markers of inflammation and oxidative stress at the start of the study and at the end of each six-week period. They found that drinking muscadine wine significantly improved skin elasticity (a loss of elasticity is what causes skin to sag more as we age). In addition, the wine was associated with a decrease in water loss at the skin surface, a measurement that indicates the skin is providing a more effective barrier against damage.
skin #skinhealth #skinage
(P23-018-23) Dealcoholized Muscadine Wine Improved Skin Health, Reduced Oxidative Stress and Inflammation in Women in a Randomized Controlled Trial
Skin, muscadine, skin elasticity, viscoelasticity, anti wrinkle, skin moisture, polyphenols, inflammation. Oxidative stress, anti aging, youthing, healthy skin,
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Best Type 2 Diabetes Diet Strategy?
A new randomized controlled study of people with type 2 diabetes showed that study participants who restricted eating to between noon and 8 p.m. daily lost more weight than those who reduced their overall calorie intake by counting calories. Both dieting strategies produced similar improvements in blood sugar levels.
diabetes #diet #timerestrictedeating
(OR14-01-23) Effect of 8-Hour Time Restricted Eating Versus Daily Calorie Restriction on Body Weight and Glycemic Control in Adults With Type 2 Diabetes
Diabetes, type 2 diabetes, diet, tre, time restricted eating, caloric restriction, calorie restriction, weight loss, lose weight
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A new randomized controlled study of people with type 2 diabetes showed that study participants who restricted eating to between noon and 8 p.m. daily lost more weight than those who reduced their overall calorie intake by counting calories. Both dieting strategies produced similar improvements in blood sugar levels.
diabetes #diet #timerestrictedeating
(OR14-01-23) Effect of 8-Hour Time Restricted Eating Versus Daily Calorie Restriction on Body Weight and Glycemic Control in Adults With Type 2 Diabetes
Diabetes, type 2 diabetes, diet, tre, time restricted eating, caloric restriction, calorie restriction, weight loss, lose weight
Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support
Hydroxyapatite a powerful alternative to Fluoride Show 1147 JUL 2023
In summary, the three clinical caries studies [Paszynska et al. (6), Schlagenhauf et al. (7), and the present study] as well as a number of in situ (8, 12, 13, 67) studies and in vitro studies (9, 17, 29, 39) in the field of remineralization and biofilm control, have demonstrated that hydroxyapatite serves as an efficient and safe alternative to fluoride in anticaries toothpastes for all age groups.
cavities #hydroyapatite #caries
Paszynska, E., Pawinska, M., Enax, J., Meyer, F., May, T. W., Amaechi, B. T., Limeback, H., Hernik, A., Krahel, A., Kaminska, I., Stokowska, E., & Gawriolek, M. (2023). Caries-preventing effect of a hydroxyapatite-toothpaste in adults: A 18-month double-blinded randomized clinical trial. Frontiers in Public Health, 11, 1199728. https://doi.org/10.3389/fpubh.2023.1199728
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Hydroxyapatite a powerful alternative to Fluoride Show 1147 JUL 2023
In summary, the three clinical caries studies [Paszynska et al. (6), Schlagenhauf et al. (7), and the present study] as well as a number of in situ (8, 12, 13, 67) studies and in vitro studies (9, 17, 29, 39) in the field of remineralization and biofilm control, have demonstrated that hydroxyapatite serves as an efficient and safe alternative to fluoride in anticaries toothpastes for all age groups.
cavities #hydroyapatite #caries
Paszynska, E., Pawinska, M., Enax, J., Meyer, F., May, T. W., Amaechi, B. T., Limeback, H., Hernik, A., Krahel, A., Kaminska, I., Stokowska, E., & Gawriolek, M. (2023). Caries-preventing effect of a hydroxyapatite-toothpaste in adults: A 18-month double-blinded randomized clinical trial. Frontiers in Public Health, 11, 1199728. https://doi.org/10.3389/fpubh.2023.1199728
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Ancient Honey Vinegar Mixture, Powerful Medicine
The mixture of honey and vinegar, also known as oxymel, has been used as a medical treatment throughout history and now scientists have established that this combination could have modern applications in the treatment of wounds.
oxymel #honey #vinegar
Freya Harrison, Anisa Blower, Christopher de Wolf, Erin Connelly. Sweet and sour synergy: exploring the antibacterial and antibiofilm activity of acetic acid and vinegar combined with medical-grade honeys. Microbiology, 2023; 169 (7) DOI: 10.1099/mic.0.001351
Honey, manuka honey, vinegar, fermented vinegar, oxymel, oximel, hydromel, squill oxymel, infections, inflammation, bacterial infections, wound healing, pomegranate vinegars, antibacterial, ancient remedy, pathogenic bacteria, honey vinegar solutions
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Ancient Honey Vinegar Mixture, Powerful Medicine
The mixture of honey and vinegar, also known as oxymel, has been used as a medical treatment throughout history and now scientists have established that this combination could have modern applications in the treatment of wounds.
oxymel #honey #vinegar
Freya Harrison, Anisa Blower, Christopher de Wolf, Erin Connelly. Sweet and sour synergy: exploring the antibacterial and antibiofilm activity of acetic acid and vinegar combined with medical-grade honeys. Microbiology, 2023; 169 (7) DOI: 10.1099/mic.0.001351
Honey, manuka honey, vinegar, fermented vinegar, oxymel, oximel, hydromel, squill oxymel, infections, inflammation, bacterial infections, wound healing, pomegranate vinegars, antibacterial, ancient remedy, pathogenic bacteria, honey vinegar solutions
Support this podcast: https://podcasters.spotify.com/pod/show/ralph-turchiano/support
DIM may be a Mighty Tooth Protector
Most of the world's population either chronically suffers from plaque and dental cavities or will develop them at some point in their lives. Toothpastes, mouthwashes, and regular checkups do their part, but more could always be done. Ben-Gurion University of the Negev scientists and their colleagues at Sichuan University and the National University of Singapore have discovered that 3,3′-Diindolylmethane (DIM), a naturally occurring molecule also known as bisindole, reduces the biofilms that produce plaque and cavities by 90%. The molecule is also found to have anti-carcinogenic properties.
DIM #Cavities #Plaque
Baruch Y, Golberg K, Sun Q, Yew-Hoong Gin K, Marks RS, Kushmaro A. 3,3′-Diindolylmethane (DIM): A Potential Therapeutic Agent against Cariogenic Streptococcus mutans Biofilm. Antibiotics. 2023; 12(6):1017. https://doi.org/10.3390/antibiotics12061017
DIM, Cavity Fighter, S.Mutans, Oral Health, Oral Microbiome, Diindolylmethane, biofilm, teeth, tooth, cavity preventer, anti-plaque, healthy mouth, natural anti-biofilm agents, extracellular polymeric substance, toothpaste, mouthwash
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MSM and Knee Pain
Both clinical and pre-clinical animal studies have supported the therapeutic usefulness of MSM for joint diseases such as OA; however, there is no direct evidence to support prophylactic use for joint diseases or use to maintain the normal condition of joints in a healthy population. In the present study, we conducted a randomized, double-blind, placebo-controlled trial of oral consumption of MSM on mild pain of the knee joint in healthy participants.
MSM #methylsulfonylmethane #KneePain
Toguchi, A., Noguchi, N., Kanno, T., & Yamada, A. (2023). Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients, 15(13), 2995. https://doi.org/10.3390/nu15132995
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Both clinical and pre-clinical animal studies have supported the therapeutic usefulness of MSM for joint diseases such as OA; however, there is no direct evidence to support prophylactic use for joint diseases or use to maintain the normal condition of joints in a healthy population. In the present study, we conducted a randomized, double-blind, placebo-controlled trial of oral consumption of MSM on mild pain of the knee joint in healthy participants.
MSM #methylsulfonylmethane #KneePain
Toguchi, A., Noguchi, N., Kanno, T., & Yamada, A. (2023). Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients, 15(13), 2995. https://doi.org/10.3390/nu15132995
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“In a long series of studies, we have shown that increasing amounts of lutein and zeaxanthin in the retina and brain decrease glare disability and discomfort and improve chromatic contrast and visual-motor reaction time, and supplementing these compounds facilitates executive functions like problem-solving and memory. All of these tasks are particularly important for athletes,”
vision #lutein #zeaxanthin
Harth, Jacob B.1; Renzi-Hammond, Lisa M.1,2; Hammond, Billy R. Jr2. A Dietary Strategy for Optimizing the Visual Range of Athletes. Exercise and Sport Sciences Reviews 51(3):p 103-108, July 2023. | DOI: 10.1249/JES.0000000000000318
Visual range, distance vision, macular pigment optical density . reaction speed, yellow pigment , blue light, contrast, visual-motor function, executive cognition, glare disability, photo stress, chromatic contrast, athletic performance, coincidence anticipation ability, carotenoid
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How far can you see, Lutein and Zeaxanthin
“In a long series of studies, we have shown that increasing amounts of lutein and zeaxanthin in the retina and brain decrease glare disability and discomfort and improve chromatic contrast and visual-motor reaction time, and supplementing these compounds facilitates executive functions like problem-solving and memory. All of these tasks are particularly important for athletes,”
vision #lutein #zeaxanthin
Harth, Jacob B.1; Renzi-Hammond, Lisa M.1,2; Hammond, Billy R. Jr2. A Dietary Strategy for Optimizing the Visual Range of Athletes. Exercise and Sport Sciences Reviews 51(3):p 103-108, July 2023. | DOI: 10.1249/JES.0000000000000318
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The researchers found that taurine suppressed age-associated weight gain in female mice (even in “menopausal” mice), increased energy expenditure, increased bone mass, improved muscle endurance and strength, reduced depression-like and anxious behaviors, reduced insulin resistance, and promoted a younger-looking immune system, among other benefits.
“Not only did we find that the animals lived longer, we also found that they’re living healthier lives,” Yadav says.
taurine #aging #health
Singh, P., Gollapalli, K., Mangiola, S., Schranner, D., Yusuf, M. A., Chamoli, M., Shi, S. L., Bastos, B. L., Nair, T., Riermeier, A., Vayndorf, E. M., Wu, J. Z., Nilakhe, A., Nguyen, C. Q., Muir, M., Kiflezghi, M. G., Foulger, A., Junker, A., Devine, J., . . . Yadav, V. K. (2023). Taurine deficiency as a driver of aging. Science. https://doi.org/abn9257
Taurine, serum concentration, aging, anti-aging, disease, hypotaurine, type 2 diabetes, wbc, insulin, bmi. Metabolism, waist circumference, N-acetyl taurine, exercise, hemoglobin, platelets, circulating taurine, age-associated pathologies, lower glucose
Taurine and a Longer, Healthier Life #taurine #hypotaurine #stem #aging #health #longlife #endurance #strength #youthfulskin #nacetyltaurine #antiaging
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The researchers found that taurine suppressed age-associated weight gain in female mice (even in “menopausal” mice), increased energy expenditure, increased bone mass, improved muscle endurance and strength, reduced depression-like and anxious behaviors, reduced insulin resistance, and promoted a younger-looking immune system, among other benefits.
“Not only did we find that the animals lived longer, we also found that they’re living healthier lives,” Yadav says.
taurine #aging #health
Singh, P., Gollapalli, K., Mangiola, S., Schranner, D., Yusuf, M. A., Chamoli, M., Shi, S. L., Bastos, B. L., Nair, T., Riermeier, A., Vayndorf, E. M., Wu, J. Z., Nilakhe, A., Nguyen, C. Q., Muir, M., Kiflezghi, M. G., Foulger, A., Junker, A., Devine, J., . . . Yadav, V. K. (2023). Taurine deficiency as a driver of aging. Science. https://doi.org/abn9257
Taurine, serum concentration, aging, anti-aging, disease, hypotaurine, type 2 diabetes, wbc, insulin, bmi. Metabolism, waist circumference, N-acetyl taurine, exercise, hemoglobin, platelets, circulating taurine, age-associated pathologies, lower glucose
Taurine and a Longer, Healthier Life #taurine #hypotaurine #stem #aging #health #longlife #endurance #strength #youthfulskin #nacetyltaurine #antiaging
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Frailty and Flavonols Episode 1141 JUN 2023
Frailty and Flavonols
Other subclasses showed no association (P values range: 0.12–0.99), but every 10 mg/d of higher quercetin intake was associated with 35% lower odds of frailty onset (OR: 0.65; 95% CI: 0.48–0.88).
Frailty #quercetin #flavonols
Oei, S., Millar, C. L., Nguyen Lily, T. N., Mukamal, K. J., Kiel, D. P., Lipsitz, L. A., Hannan, M. T., & Sahni, S. (2023). Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2023.04.013
Frailty, falling, weakness, quercetin, flavonols, osteoporosis, sarcopenia. kaempferol , myricetin, aging, elderly, fisetin, strength, balance
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Frailty and Flavonols Episode 1141 JUN 2023
Other subclasses showed no association (P values range: 0.12–0.99), but every 10 mg/d of higher quercetin intake was associated with 35% lower odds of frailty onset (OR: 0.65; 95% CI: 0.48–0.88).
Frailty #quercetin #flavonols
Oei, S., Millar, C. L., Nguyen Lily, T. N., Mukamal, K. J., Kiel, D. P., Lipsitz, L. A., Hannan, M. T., & Sahni, S. (2023). Higher intake of dietary flavonols, specifically dietary quercetin, is associated with lower odds of frailty onset over 12 years of follow-up among adults in the Framingham Heart Study. The American Journal of Clinical Nutrition. https://doi.org/10.1016/j.ajcnut.2023.04.013
Frailty, falling, weakness, quercetin, flavonols, osteoporosis, sarcopenia. kaempferol , myricetin, aging, elderly, fisetin, strength, balance
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The MIT group is not the first to show that gamma frequency tactile stimulation can affect brain activity and improve motor function, but they are the first to show that the stimulation can also reduce levels of the hallmark Alzheimer’s protein phosphorylated tau, keep neurons from dying or losing their synapse circuit connections, and reduce neural DNA damage.
Vibrotactile #Alzheimers #tau
Suk, H., Buie, N., Xu, G., Banerjee, A., Boyden, E. S., & Tsai, L. (2023). Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function. Frontiers in Aging Neuroscience, 15. https://doi.org/10.3389/fnagi.2023.1129510
Neurodegenerative, dementia, Alzheimer’s, tau, somatosensory cortex, primary motor cortex, motor function, gamma frequency, 40hz, Vibrotactile stimulation, GENUS, for Gamma Entrainment Using Sensory stimuli, als, ftd, Pick disease, progressive supranuclear palsy, tauopathies, frontotemporal dementia, Parkinson’s disease
Gamma Frequency clears brain debris and improves motor function #40hz #vibrotactile #stem #neurodegenerative #dementia #tau #alzheimer #cortex #brain
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The MIT group is not the first to show that gamma frequency tactile stimulation can affect brain activity and improve motor function, but they are the first to show that the stimulation can also reduce levels of the hallmark Alzheimer’s protein phosphorylated tau, keep neurons from dying or losing their synapse circuit connections, and reduce neural DNA damage.
Vibrotactile #Alzheimers #tau
Suk, H., Buie, N., Xu, G., Banerjee, A., Boyden, E. S., & Tsai, L. (2023). Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function. Frontiers in Aging Neuroscience, 15. https://doi.org/10.3389/fnagi.2023.1129510
Neurodegenerative, dementia, Alzheimer’s, tau, somatosensory cortex, primary motor cortex, motor function, gamma frequency, 40hz, Vibrotactile stimulation, GENUS, for Gamma Entrainment Using Sensory stimuli, als, ftd, Pick disease, progressive supranuclear palsy, tauopathies, frontotemporal dementia, Parkinson’s disease
Gamma Frequency clears brain debris and improves motor function #40hz #vibrotactile #stem #neurodegenerative #dementia #tau #alzheimer #cortex #brain
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Ear acupuncture with beads may help shed the pounds Episode 1139 MAY 2023
The study found substantial differences after 3 months, with participants losing on average 10.4cm off their waist circumference (from an average 98.4cm at the start of the study to 88cm) and 4% of total body fat (from average 28.2% to 24.3%).
auricular #ear #weightloss
Poster presentation PO4.085 at the European Congress on Obesity (ECO) Dublin, Ireland (17-20 May 2023)
Auricular, ear, acupuncture, acupressure, appetite, metabolism, weight loss, bmi, hunger, digestion, vagus nerve, beads, acupoint stimulation
Ear acupuncture with beads may help shed the pounds #ear #stem #auricular #acupuncture #acupressure #weightloss #bmi #vagusnerve #metabolism
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Ear acupuncture with beads may help shed the pounds. Episode 1139 MAY 2023
The study found substantial differences after 3 months, with participants losing on average 10.4cm off their waist circumference (from an average 98.4cm at the start of the study to 88cm) and 4% of total body fat (from average 28.2% to 24.3%).
auricular #ear #weightloss
Poster presentation PO4.085 at the European Congress on Obesity (ECO) Dublin, Ireland (17-20 May 2023)
Auricular, ear, acupuncture, acupressure, appetite, metabolism, weight loss, bmi, hunger, digestion, vagus nerve, beads, acupoint stimulation
Ear acupuncture with beads may help shed the pounds #ear #stem #auricular #acupuncture #acupressure #weightloss #bmi #vagusnerve #metabolism
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The manipulation of the timing and dose of kiwifruit mayhave applications in terms of sleep and recovery (e.g., antioxidant consumptionin relation to training) in athletes that warrant further investigation. Theresults presented suggest a potential role for kiwifruit consumption in sleeppromotion and recovery protocols for elite athletes. Consuming 2 kiwifruit 1 hbefore bed is a practical wholefood-based intervention that can easily beimplemented in real-world settings. Kiwifruit is available in wholefood form,but it is also consumed in various processed forms, e.g., drinks, sweets,lyophilised products (i.e., freeze dried), dehydrated products and juices [64].Further research is warranted to develop protocols and/or products designedspecifically to promote sleep and/or recovery in elite athletes.
kiwi #exercise #sleep
Doherty, R., Madigan, S., Nevill, A., Warrington, G., &Ellis, J. G. (2023). The Impact of Kiwifruit Consumption on the Sleep and Recoveryof Elite Athletes. Nutrients, 15(10), 2274. https://doi.org/10.3390/nu15102274
Kiwi, kiwifruit, sleep, Actinidia Deliciosa, training, recovery, disturbed sleep, anxiety ,vitamin c, serotonin, melatonin, folate, Regulatory, Satisfaction, Alertness,Timing, Efficiency, athletes, exercise, overtraining, restful sleep, protocol,wholefood, unexplained underperformance syndrome, uup, overtraining, RU-SATED
Kiwi Fruit Improved Sleep and Recovery Episode 1138 MAY 2023#kiwi🥝 #kiwi #kiwifruit #stem #sleep #insomnia #training #rest #wholefood#athletes
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The manipulation of the timing and dose of kiwifruit mayhave applications in terms of sleep and recovery (e.g., antioxidant consumptionin relation to training) in athletes that warrant further investigation. Theresults presented suggest a potential role for kiwifruit consumption in sleeppromotion and recovery protocols for elite athletes. Consuming 2 kiwifruit 1 hbefore bed is a practical wholefood-based intervention that can easily beimplemented in real-world settings. Kiwifruit is available in wholefood form,but it is also consumed in various processed forms, e.g., drinks, sweets,lyophilised products (i.e., freeze dried), dehydrated products and juices [64].Further research is warranted to develop protocols and/or products designedspecifically to promote sleep and/or recovery in elite athletes.
kiwi #exercise #sleep
Doherty, R., Madigan, S., Nevill, A., Warrington, G., &Ellis, J. G. (2023). The Impact of Kiwifruit Consumption on the Sleep and Recoveryof Elite Athletes. Nutrients, 15(10), 2274. https://doi.org/10.3390/nu15102274
Kiwi, kiwifruit, sleep, Actinidia Deliciosa, training, recovery, disturbed sleep, anxiety ,vitamin c, serotonin, melatonin, folate, Regulatory, Satisfaction, Alertness,Timing, Efficiency, athletes, exercise, overtraining, restful sleep, protocol,wholefood, unexplained underperformance syndrome, uup, overtraining, RU-SATED
Kiwi Fruit Improved Sleep and Recovery Episode 1138 MAY 2023#kiwi🥝 #kiwi #kiwifruit #stem #sleep #insomnia #training #rest #wholefood#athletes
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Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023
The results of this study provide proof-of-concept that GlyNAC supplementation improves age-associated cognitive decline and supports brain health in aging by improving/correcting brain GSH deficiency, elevated OxS, mitochondrial dysfunction, abnormal mitophagy and autophagy, inflammation, impaired glucose transport/uptake, elevated genomic damage, and reversing the decline in brain neurotrophic growth factors. GlyNAC could be a simple and effective nutritional supplement to support brain health and cognitive function in aging, and warrants additional investigation.
glynac #brainrespiration #cognition
Kumar, P., Osahon, O. W., & Sekhar, R. V. (2023). GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Glutathione Deficiency, Oxidative Stress, Glucose Uptake, Mitochondrial Dysfunction, Genomic Damage, Inflammation and Neurotrophic Factors to Reverse Age-Associated Cognitive Decline: Implications for Improving Brain Health in Aging. Antioxidants, 12(5), 1042. https://doi.org/10.3390/antiox12051042
Glynac, glycine, N-Acetylcysteine, correction, GSH Synthesis , cognitive improvement, brain health, GSH, OxS, mitochondrial energetics, autophagy/mitophagy, glucose transporters, inflammation, genomic damage, neurotrophic factors
Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023 #glynac #glycine #nacetylcysteine #brain #aging #brainheath #stem
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Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023
The results of this study provide proof-of-concept that GlyNAC supplementation improves age-associated cognitive decline and supports brain health in aging by improving/correcting brain GSH deficiency, elevated OxS, mitochondrial dysfunction, abnormal mitophagy and autophagy, inflammation, impaired glucose transport/uptake, elevated genomic damage, and reversing the decline in brain neurotrophic growth factors. GlyNAC could be a simple and effective nutritional supplement to support brain health and cognitive function in aging, and warrants additional investigation.
glynac #brainrespiration #cognition
Kumar, P., Osahon, O. W., & Sekhar, R. V. (2023). GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Old Mice Improves Brain Glutathione Deficiency, Oxidative Stress, Glucose Uptake, Mitochondrial Dysfunction, Genomic Damage, Inflammation and Neurotrophic Factors to Reverse Age-Associated Cognitive Decline: Implications for Improving Brain Health in Aging. Antioxidants, 12(5), 1042. https://doi.org/10.3390/antiox12051042
Glynac, glycine, N-Acetylcysteine, correction, GSH Synthesis , cognitive improvement, brain health, GSH, OxS, mitochondrial energetics, autophagy/mitophagy, glucose transporters, inflammation, genomic damage, neurotrophic factors
Brain Energy and Function, Improved with Glycine/NAC? Episode 1137 MAY 2023 #glynac #glycine #nacetylcysteine #brain #aging #brainheath #stem
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Testosterone And Enokitake Mushroom Show 1135 MAY 2023
This study showed that the ingestion of adenosine-containing mushrooms and vegetables may effectively increase testicular testosterone production. We conclude that mushrooms with a relatively high adenosine content, such as enokitake, may be useful against aging and fatigue.
enokitake #testosterone #leydig
Iguchi, K., Nagashima, K., Mochizuki, J., Yamamoto, H., Unno, K., & Miyoshi, N. (2023). Enokitake Mushroom and Its Active Component, Adenosine, Which Restores Testosterone Production in Impaired and Fatigued Mouse Models. Nutrients, 15(9), 2142. https://doi.org/10.3390/nu15092142
Adenosine, enokitake mushroom, enoki, testosterone, male menopause, mushrooms, Leydig cells, polyphenols, Flammulina velutipes. Golden needle, winter mushroom, fatigue, anti aging,
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Testosterone And Enokitake Mushroom Show 1135 MAY 2023
This study showed that the ingestion of adenosine-containing mushrooms and vegetables may effectively increase testicular testosterone production. We conclude that mushrooms with a relatively high adenosine content, such as enokitake, may be useful against aging and fatigue.
enokitake #testosterone #leydig
Iguchi, K., Nagashima, K., Mochizuki, J., Yamamoto, H., Unno, K., & Miyoshi, N. (2023). Enokitake Mushroom and Its Active Component, Adenosine, Which Restores Testosterone Production in Impaired and Fatigued Mouse Models. Nutrients, 15(9), 2142. https://doi.org/10.3390/nu15092142
Adenosine, enokitake mushroom, enoki, testosterone, male menopause, mushrooms, Leydig cells, polyphenols, Flammulina velutipes. Golden needle, winter mushroom, fatigue, anti aging,
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Inhaled ethanol may treat respiratory infections and stop pandemics
The scientists think that the ethanol vapor must increase ethanol concentrations in the fluid to 20% to successfully treat the infection. This concentration is not toxic to lung cells the scientists created in the lab to mimic human cells. At body temperature, 20% ethanol can not only inactivate the influenza A virus outside of the cells in one minute, but also stop the virus from replicating inside these cells.
Tamai, M., Taba, S., Mise, T., Yamashita, M., Ishikawa, H., & Shintake, T. Effect of Ethanol Vapor Inhalation Treatment on Lethal Respiratory Viral Infection With Influenza A. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiad089
Influenza A virus, ethanol, Influenza , Avian Flu, Sars COV 2, coronavirus, inhalation, enveloped virus, etoh vapor, progeny virus, respiratory infections, severe acute respiratory syndrome coronavirus 2
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The scientists think that the ethanol vapor must increase ethanol concentrations in the fluid to 20% to successfully treat the infection. This concentration is not toxic to lung cells the scientists created in the lab to mimic human cells. At body temperature, 20% ethanol can not only inactivate the influenza A virus outside of the cells in one minute, but also stop the virus from replicating inside these cells.
Tamai, M., Taba, S., Mise, T., Yamashita, M., Ishikawa, H., & Shintake, T. Effect of Ethanol Vapor Inhalation Treatment on Lethal Respiratory Viral Infection With Influenza A. The Journal of Infectious Diseases. https://doi.org/10.1093/infdis/jiad089
Influenza A virus, ethanol, Influenza , Avian Flu, Sars COV 2, coronavirus, inhalation, enveloped virus, etoh vapor, progeny virus, respiratory infections, severe acute respiratory syndrome coronavirus 2
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"Remarkably, the cognitive scores increased to levels similar to undergraduates taking the same cognitive tests for the first time," Wu said. "Our finding of continuous cognitive growth in older adulthood is unique because most studies show only maintenance of cognitive abilities or cognitive decline over time."
Leah Ferguson, Debaleena Sain, Esra Kürüm, Carla M. Strickland-Hughes, George W. Rebok, Rachel Wu. One-year cognitive outcomes from a multiple real-world skill learning intervention with older adults. Aging & Mental Health, 2023; 1 DOI: 10.1080/13607863.2023.2197847
brain #cognitive #aging
Musical expertise makes older adults better listeners by keeping brain young
"Playing music makes older adults better listeners by preserving youthful neural patterns as well as recruiting additional compensatory brain regions. Our study provides empirical evidence to support that playing music keeps your brain sharp, young, and focused,” said Dr. DU, corresponding author of this study.
Zhang, L., Wang, X., Alain, C., & Du, Y. (2023). Successful aging of musicians: Preservation of sensorimotor regions aids audiovisual speech-in-noise perception. Science Advances. https://doi.org/adg7056
Cognition, learning, DMN, frontoparietal, cognitive control, working memory, episodic memory, default mode network, continuous cognitive growth, successful aging, youthful brain, dementia, Alzheimers, speech processing, reverse aging brain, improve brain function, older learners
Older Brains learn to Outperform Younger Ones #aging #successfulaging #brain #cognition #memory #learning #stem #DMN #workingmemory #episodicmemory
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"Remarkably, the cognitive scores increased to levels similar to undergraduates taking the same cognitive tests for the first time," Wu said. "Our finding of continuous cognitive growth in older adulthood is unique because most studies show only maintenance of cognitive abilities or cognitive decline over time."
Leah Ferguson, Debaleena Sain, Esra Kürüm, Carla M. Strickland-Hughes, George W. Rebok, Rachel Wu. One-year cognitive outcomes from a multiple real-world skill learning intervention with older adults. Aging & Mental Health, 2023; 1 DOI: 10.1080/13607863.2023.2197847
brain #cognitive #aging
Musical expertise makes older adults better listeners by keeping brain young
"Playing music makes older adults better listeners by preserving youthful neural patterns as well as recruiting additional compensatory brain regions. Our study provides empirical evidence to support that playing music keeps your brain sharp, young, and focused,” said Dr. DU, corresponding author of this study.
Zhang, L., Wang, X., Alain, C., & Du, Y. (2023). Successful aging of musicians: Preservation of sensorimotor regions aids audiovisual speech-in-noise perception. Science Advances. https://doi.org/adg7056
Cognition, learning, DMN, frontoparietal, cognitive control, working memory, episodic memory, default mode network, continuous cognitive growth, successful aging, youthful brain, dementia, Alzheimers, speech processing, reverse aging brain, improve brain function, older learners
Older Brains learn to Outperform Younger Ones #aging #successfulaging #brain #cognition #memory #learning #stem #DMN #workingmemory #episodicmemory
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In summary, this RCT, evaluating the functionality of daily consumption of flaxseed oil containing 2.2 g of ALA, improved verbal fluency in healthy individuals aged between 65 to 80 years, with no abnormalities in cognitive function, despite declines with age. Since the improvement in verbal fluency is significant in cognitive health, as it is one of the factors of Alzheimer’s disease progress [37], further validation studies, with a focus on ALA’s impact on verbal fluency and executive function, are needed to extend the obtained evidence in this study to older adults.
Ogawa, T., Sawane, K., Ookoshi, K., & Kawashima, R. (2023). Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults. Nutrients, 15(6), 1499. https://doi.org/10.3390/nu15061499
flaxseedoil #verbalfluency #executivefunction
Ala, cognitive function, age, flax seed oil, executive function, Alzheimer’s , verbal fluency, dha, alpha linolenic acid, docosahexaenoic acid
Flax Seed Oil Brain Function Verbal Fluency #flaxseedoil #verbalfluency #stem #cognitivefunctions #ala #alphalinolenicacid #dha #docosahexaenoicacid #agingwell Ogawa, T., Sawane, K., Ookoshi, K., & Kawashima, R. (2023). Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid Improves Verbal Fluency in Healthy Older Adults.
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In summary, this RCT, evaluating the functionality of dailyconsumption of flaxseed oil containing 2.2 g of ALA, improved verbal fluency inhealthy individuals aged between 65 to 80 years, with no abnormalities incognitive function, despite declines with age. Since the improvement in verbalfluency is significant in cognitive health, as it is one of the factors ofAlzheimer’s disease progress [37], further validation studies, with a focus onALA’s impact on verbal fluency and executive function, are needed to extend theobtained evidence in this study to older adults.
Ogawa, T., Sawane, K., Ookoshi, K., & Kawashima, R.(2023). Supplementation with Flaxseed Oil Rich in Alpha-Linolenic Acid ImprovesVerbal Fluency in Healthy Older Adults. Nutrients, 15(6), 1499. https://doi.org/10.3390/nu15061499
flaxseedoil #verbalfluency #executivefunction
Ala, cognitive function, age, flax seed oil, executivefunction, Alzheimer’s , verbal fluency, dha, alpha linolenic acid, docosahexaenoicacid
Flax Seed Oil Brain Function Verbal Fluency #flaxseedoil#verbalfluency #stem #cognitivefunctions #ala #alphalinolenicacid #dha#docosahexaenoicacid #agingwell Ogawa, T., Sawane, K., Ookoshi, K., &Kawashima, R. (2023). Supplementation with Flaxseed Oil Rich in Alpha-LinolenicAcid Improves Verbal Fluency in Healthy Older Adults.
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There was a statistically significant (p=.039) difference in the participants' mean biological age before (55.83 years) and after (51.23 years) the 8-week diet and lifestyle intervention, with an average decrease of 4.60 years. The average chronological age at the start of the program was 57.9 years and all but one participant had a biological age younger than their chronological age at the start of the program, suggesting that biological age changes were unrelated to disease improvement and instead might be attributed to underlying aging mechanisms.
agereversal #methylationdiet #biologicalage
Fitzgerald KN, Campbell T, Makarem S, Hodges R. Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series. Aging (Albany NY). 2023 Mar 22; 15:1833-1839 . https://doi.org/10.18632/aging.204602
DNA methylation, age reversal, biological age, health span, life span, longevity, polyphenolic modulators of DNA methyl transferase, ten-eleven translocation (TET) demethylase cofactors, DMNT, a methylation-supportive diet, epinutrients, curcumin, epigallocatechin gallate (EGCG), rosmarinic acid, quercetin, luteolin
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There was a statistically significant (p=.039) difference in the participants' mean biological age before (55.83 years) and after (51.23 years) the 8-week diet and lifestyle intervention, with an average decrease of 4.60 years. The average chronological age at the start of the program was 57.9 years and all but one participant had a biological age younger than their chronological age at the start of the program, suggesting that biological age changes were unrelated to disease improvement and instead might be attributed to underlying aging mechanisms.
agereversal #methylationdiet #biologicalage
Fitzgerald KN, Campbell T, Makarem S, Hodges R. Potential reversal of biological age in women following an 8-week methylation-supportive diet and lifestyle program: a case series. Aging (Albany NY). 2023 Mar 22; 15:1833-1839 . https://doi.org/10.18632/aging.204602
DNA methylation, age reversal, biological age, health span, life span, longevity, polyphenolic modulators of DNA methyl transferase, ten-eleven translocation (TET) demethylase cofactors, DMNT, a methylation-supportive diet, epinutrients, curcumin, epigallocatechin gallate (EGCG), rosmarinic acid, quercetin, luteolin
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Near Infrared Light and Heart Health Episode 1130 APR 2023
PBM therapy has demonstrated efficacy in a broad range ofneurocognitive and musculoskeletal diseases such as Parkinson's disease,depression, age-related dry macular degeneration, chronic wounds, arthritis,knee osteoarthritis, tendinopathy, and oral mucositis among many others
Photobiomodulation #heartdisease #850nm
Syed, SB, Ahmet, I, Chakir, K, Morrell,CH, Arany, PR, Lakatta, EG. Photobiomodulation therapy mitigatescardiovascular aging and improves survival. Lasers SurgMed. 2023; 55: 278– 293. https://doi.org/10.1002/lsm.23644
Photobiomodulation, heart disease, coronary disease, healing,near infrared light, 850 nm, PBM, TGF, nonvisual phototransduction pathways, transforminggrowth factor beta , light therapy, Parkinson'sdisease, depression, age-related dry macular degeneration, chronic wounds,arthritis, knee osteoarthritis, tendinopathy,
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PBM therapy has demonstrated efficacy in a broad range ofneurocognitive and musculoskeletal diseases such as Parkinson's disease,depression, age-related dry macular degeneration, chronic wounds, arthritis,knee osteoarthritis, tendinopathy, and oral mucositis among many others
Photobiomodulation #heartdisease #850nm
Syed, SB, Ahmet, I, Chakir, K, Morrell,CH, Arany, PR, Lakatta, EG. Photobiomodulation therapy mitigatescardiovascular aging and improves survival. Lasers SurgMed. 2023; 55: 278– 293. https://doi.org/10.1002/lsm.23644
Photobiomodulation, heart disease, coronary disease, healing,near infrared light, 850 nm, PBM, TGF, nonvisual phototransduction pathways, transforminggrowth factor beta , light therapy, Parkinson'sdisease, depression, age-related dry macular degeneration, chronic wounds,arthritis, knee osteoarthritis, tendinopathy,
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In conclusion, the results of this study indicated that BA supplementationenhanced cognitive performance in older adults whose baseline cognitive levelswere borderline to below normal. In addition, taking BA supplementation wasable to reduce symptoms of depression.
betaalanine #depression #brain
Ostfeld I,Ben-Zeev T, Zamir A, Levi C, Gepner Y, Springer S, Hoffman JR. Role ofβ-Alanine Supplementation on Cognitive Function, Mood, and Physical Function inOlder Adults; Double-Blind Randomized Controlled Study. Nutrients. 2023;15(4):923. https://doi.org/10.3390/nu15040923
Beta alanine, geriatric depression, cognitive, Montreal cognitive scale, neuroinflammation, older,senior citizen, amino acid, mood, stress, cognitive function, improve, feelbetter, symptoms, supplementation, cognitive decline, enhanced cognitiveperformance, Moca, GDS
betaalanine #mood #brainfunction #depressionanxiety #neuroinflammation #cognitivefunctions
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In conclusion, the results of this study indicated that BA supplementationenhanced cognitive performance in older adults whose baseline cognitive levelswere borderline to below normal. In addition, taking BA supplementation wasable to reduce symptoms of depression.
betaalanine#depression #brain
Ostfeld I,Ben-Zeev T, Zamir A, Levi C, Gepner Y, Springer S, Hoffman JR. Role ofβ-Alanine Supplementation on Cognitive Function, Mood, and Physical Function inOlder Adults; Double-Blind Randomized Controlled Study. Nutrients. 2023;15(4):923. https://doi.org/10.3390/nu15040923
Beta alanine,geriatric depression, cognitive, Montreal cognitive scale, neuroinflammation, older,senior citizen, amino acid, mood, stress, cognitive function, improve, feelbetter, symptoms, supplementation, cognitive decline, enhanced cognitiveperformance, Moca, GDS
betaalanine#mood #brainfunction #depressionanxiety #neuroinflammation #cognitivefunctions
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The current study demonstrated that a 14-day intake of 25 gof freeze-dried WBs, supplying 375 mg of anthocyanins and approximately 1 cupof fresh fruit equivalent, significantly increased FAT-ox rates, decreasedCHO-ox rates, and led to lower blood lactate values without changes in glyceroland FA concentrations during 40 min of cycling at 65% of vo2peak inendurance-trained males. These findings may have potential effects on enduranceexercise performance.
blueberries #lactate #metabolism
Pilolla KD, Armendariz J, Burrus BM, Baston DS, McCarthy KA,Bloedon TK. Effects of Wild Blueberries on Fat Oxidation Rates in AerobicallyTrained Males. Nutrients. 2023; 15(6):1339. https://doi.org/10.3390/nu15061339
Anthocyanins, polyphenols, wild blueberry, fatty acidoxidation, lipolysis, exercise, endurance, carbohydrates, glycogen sparing, blueberries.Blueberry, metabolism, FAT-ox, CHO-ox
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The current study demonstrated that a 14-day intake of 25 gof freeze-dried WBs, supplying 375 mg of anthocyanins and approximately 1 cupof fresh fruit equivalent, significantly increased FAT-ox rates, decreasedCHO-ox rates, and led to lower blood lactate values without changes in glyceroland FA concentrations during 40 min of cycling at 65% of vo2peak inendurance-trained males. These findings may have potential effects on enduranceexercise performance.
blueberries #lactate #metabolism
Pilolla KD, Armendariz J, Burrus BM, Baston DS, McCarthy KA,Bloedon TK. Effects of Wild Blueberries on Fat Oxidation Rates in AerobicallyTrained Males. Nutrients. 2023; 15(6):1339. https://doi.org/10.3390/nu15061339
Anthocyanins, polyphenols, wild blueberry, fatty acidoxidation, lipolysis, exercise, endurance, carbohydrates, glycogen sparing, blueberries.Blueberry, metabolism, FAT-ox, CHO-ox
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“We found that reduced oxygen cost and improved running economy, as well as improvements in acute recovery, indicate it could potentially benefit those who are undertaking regular aerobic exercise training.”
olivefruitwater #hydroxytyrosol #exercise
Roberts JD, Lillis JB, Pinto JM, Chichger H, López-Samanes Á, Coso JD, Zacca R, Willmott AGB. The Effect of a Hydroxytyrosol-Rich, Olive-Derived Phytocomplex on Aerobic Exercise and Acute Recovery. Nutrients. 2023; 15(2):421. https://doi.org/10.3390/nu1502042
Olive fruit water, hydroxytyrosol, aerobic capacity, exercise, running, polyphenols, exercise recovery, endurance, lactate threshold, running economy
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“We found that reduced oxygen cost and improved running economy, as well as improvements in acute recovery, indicate it could potentially benefit those who are undertaking regular aerobic exercise training.”
olivefruitwater #hydroxytyrosol #exercise
Roberts JD, Lillis JB, Pinto JM, Chichger H, López-Samanes Á, Coso JD, Zacca R, Willmott AGB. The Effect of a Hydroxytyrosol-Rich, Olive-Derived Phytocomplex on Aerobic Exercise and Acute Recovery. Nutrients. 2023; 15(2):421. https://doi.org/10.3390/nu1502042
Olive fruit water, hydroxytyrosol, aerobic capacity, exercise, running, polyphenols, exercise recovery, endurance, lactate threshold, running economy
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(ABSTRACT) With over 6 million coronavirus pandemic deaths, the African continent reported the lowest death rate despite having a high disease burden. The African community’s resilience to the pandemic has been attributed to climate and weather conditions, herd immunity, repeated exposure to infectious organisms that help stimulate the immune system, and a disproportionately large youth population. In addition, functional foods, herbal remedies, and dietary supplements contain micronutrients and bioactive compounds that can help boost the immune system.
africa #herbs #immune
Frazzoli C, Grasso G, Husaini DC, Ajibo DN, Orish FC, Orisakwe OE. Immune System and Epidemics: The Role of African Indigenous Bioactive Substances. Nutrients. 2023; 15(2):273. https://doi.org/10.3390/nu15020273
African herbs, Moringa oleifera, Achyranthes Aspera, Artemisia, Garcinia kola, Fermented milk, Indigenous Bioactive Substances, Garcinia kola, new castle disease virus, herpes simplex virus, Epstein-Barr virus, hepatitis B virus, camel milk,
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(ABSTRACT) With over 6 million coronavirus pandemic deaths, the African continent reported the lowest death rate despite having a high disease burden. The African community’s resilience to the pandemic has been attributed to climate and weather conditions, herd immunity, repeated exposure to infectious organisms that help stimulate the immune system, and a disproportionately large youth population. In addition, functional foods, herbal remedies, and dietary supplements contain micronutrients and bioactive compounds that can help boost the immune system.
africa #herbs #immune
Frazzoli C, Grasso G, Husaini DC, Ajibo DN, Orish FC, Orisakwe OE. Immune System and Epidemics: The Role of African Indigenous Bioactive Substances. Nutrients. 2023; 15(2):273. https://doi.org/10.3390/nu15020273
African herbs, Moringa oleifera, Achyranthes Aspera, Artemisia, Garcinia kola, Fermented milk, Indigenous Bioactive Substances, Garcinia kola, new castle disease virus, herpes simplex virus, Epstein-Barr virus, hepatitis B virus, camel milk,
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“Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer’s disease and to lower cholesterol”
oleicacid #oliveoil #mufa
Santa-María C, López-Enríquez S, Montserrat-de la Paz S, Geniz I, Reyes-Quiroz ME, Moreno M, Palomares F, Sobrino F, Alba G. Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid. Nutrients. 2023; 15(1):224. https://doi.org/10.3390/nu15010224
Olive oil, oleic acid, Oleoylethanolamide, polyphenol, sirt1,, Alzheimer’s disease, inflammation, hypocholesterolaemic, depression, malondialdehyde, cholesterol absorption, NAD, OA, OEA, neuroprotective effects
Olive Oil New Discoveries #oliveoil #oleicacid #oleic #oleoylethanolamide #depresion #polyphenols #neuroprotector #alzheimers
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“Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer’s disease and to lower cholesterol”
oleicacid #oliveoil #mufa
Santa-María C, López-Enríquez S, Montserrat-de la Paz S, Geniz I, Reyes-Quiroz ME, Moreno M, Palomares F, Sobrino F, Alba G. Update on Anti-Inflammatory Molecular Mechanisms Induced by Oleic Acid. Nutrients. 2023; 15(1):224. https://doi.org/10.3390/nu15010224
Olive oil, oleic acid, Oleoylethanolamide, polyphenol, sirt1,, Alzheimer’s disease, inflammation, hypocholesterolaemic, depression, malondialdehyde, cholesterol absorption, NAD, OA, OEA, neuroprotective effects
Olive Oil New Discoveries #oliveoil #oleicacid #oleic #oleoylethanolamide #depresion #polyphenols #neuroprotector #alzheimers
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Andiroba Oil Skin Healing and Scar Prevention Episode 1121 JAN 23
“The andiroba extract in wounds provides acceleration in healing process, with increase of contraction rate and local re-epithelialization, resulting in the complete closure of wounds [52].”
andiroba #scar #healing
Gomes J. T., Wanzeler A. Márcia V., Júnior S. M.A., Soares R. Helena F. Chaves, Oliveira C. P. de, Rodrigues E. de M., Soares B. M., Alcantara D. D.F.A., Burbano R. M.R., Tuji F. M. The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option. Oncotarget. 2023; 14: 23-39. Retrieved from https://www.oncotarget.com/article/28338/text/
Andiroba oil, seed oil, scar prevention, skin ulcers, oral mucositis, chemotherapy damage, radiation damage, chemotherapy, cancer therapy, cuts, skin healing, youthful skin, skin regeneration, wound healing, ulcer healing, natural, topical
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“The andiroba extract in wounds provides acceleration in healing process, with increase of contraction rate and local re-epithelialization, resulting in the complete closure of wounds [52].”
andiroba #scar #healing
Gomes J. T., Wanzeler A. Márcia V., Júnior S. M.A., Soares R. Helena F. Chaves, Oliveira C. P. de, Rodrigues E. de M., Soares B. M., Alcantara D. D.F.A., Burbano R. M.R., Tuji F. M. The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option. Oncotarget. 2023; 14: 23-39. Retrieved from https://www.oncotarget.com/article/28338/text/
Andiroba oil, seed oil, scar prevention, skin ulcers, oral mucositis, chemotherapy damage, radiation damage, chemotherapy, cancer therapy, cuts, skin healing, youthful skin, skin regeneration, wound healing, ulcer healing, natural, topical
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Almonds A Workout Superfood
improved mitochondrial function, reduced fat mass, fasting insulin and triglycerides, and is elevated in the blood compartment after an acute bout of exercise in both male and female subjects (57). In general, the elevated post-exercise plasma levels of 12,13-DiHOME with almond intake support positive metabolic outcomes for adults engaging in unaccustomed eccentric exercise bouts. Other almond-related benefits for exercisers revealed in this study include reduced feelings of fatigue and tension, better leg-back strength during recovery, and decreased muscle damage during the first day of recovery.
oxylipin #almonds #musclerecovery
Nieman, D. C., Omar, A. M., Kay, C. D., Kasote, D. M., Sakaguchi, C. A., Lkhagva, A., Weldemariam, M. M., & Zhang, Q. (2023). Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.1042719
Almonds, polyphenols, muscle, recovery, training, mood, endurance, stamina, octadecenoic acid , almond skin, POMS, exercise
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Almonds A Workout Superfood
improved mitochondrial function, reduced fat mass, fasting insulin and triglycerides, and is elevated in the blood compartment after an acute bout of exercise in both male and female subjects (57). In general, the elevated post-exercise plasma levels of 12,13-DiHOME with almond intake support positive metabolic outcomes for adults engaging in unaccustomed eccentric exercise bouts. Other almond-related benefits for exercisers revealed in this study include reduced feelings of fatigue and tension, better leg-back strength during recovery, and decreased muscle damage during the first day of recovery.
oxylipin #almonds #musclerecovery
Nieman, D. C., Omar, A. M., Kay, C. D., Kasote, D. M., Sakaguchi, C. A., Lkhagva, A., Weldemariam, M. M., & Zhang, Q. (2023). Almond intake alters the acute plasma dihydroxy-octadecenoic acid (DiHOME) response to eccentric exercise. Frontiers in Nutrition, 9. https://doi.org/10.3389/fnut.2022.1042719
Almonds, polyphenols, muscle, recovery, training, mood, endurance, stamina, octadecenoic acid , almond skin, POMS, exercise
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Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives
“In this review article, we aimed to summarize the current evidence for creatine supplementation in advanced chronic liver disease and primarily in sarcopenic cirrhotic patients who would potentially benefit from creatine supplementation.”
creatine #kidney #liver
Casciola R, Leoni L, Cuffari B, Pecchini M, Menozzi R, Colecchia A, Ravaioli F. Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives. Nutrients. 2023; 15(4):863. https://doi.org/10.3390/nu15040863
Creatine monohydrate, myostatin, hyperammonemia , hyperammonaemia ,healthy aging, myokine, aging, weakness, chronic liver disease, nutrition, ACLD, advanced liver diseases, portal hypertension, cirrhosis, creatine, supplementation, sarcopenia, muscle, fatigue, lipids, vldl, ammonia, cognition, brain energy, liver
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Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives
“In this review article, we aimed to summarize the current evidence for creatine supplementation in advanced chronic liver disease and primarily in sarcopenic cirrhotic patients who would potentially benefit from creatine supplementation.”
creatine #kidney #liver
Casciola R, Leoni L, Cuffari B, Pecchini M, Menozzi R, Colecchia A, Ravaioli F. Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives. Nutrients. 2023; 15(4):863. https://doi.org/10.3390/nu15040863
Creatine monohydrate, myostatin, hyperammonemia , hyperammonaemia ,healthy aging, myokine, aging, weakness, chronic liver disease, nutrition, ACLD, advanced liver diseases, portal hypertension, cirrhosis, creatine, supplementation, sarcopenia, muscle, fatigue, lipids, vldl, ammonia, cognition, brain energy, liver
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“In this review, we focus on the decrease in nicotinamide adenine dinucleotide (NAD+) with age and the supplementation of NAD+ precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), in combination with other geroprotective compounds, to restore NAD+ levels present in youth.”
NAD #NMN #geroprotective
Sharma A, Chabloz S, Lapides RA, Roider E, Ewald CY. Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan. Nutrients. 2023; 15(2):445. https://doi.org/10.3390/nu15020445
Aging, longevity, supplements, geroprotectors, SIRT1, NAD+, NMN, resveratrol, nutraceuticals, age-related diseases, flavonoids, senolytic, healthspan, EGCG, COQ10, Lycopene, Astaxanthin, Apigenein, luteolin, pterostilbene, betaine, quercetin, fisten, pronounce, CD38, PARP1, optimization, geroprotective
Optimizing Longevity with NAD+ Boosters #NMN #NR #geroprotector #longevity #SIRT #CD38 #astaxanthin #lycopene #quercitin #EGCG #pterostilbene #PARP1
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“In this review, we focus on the decrease in nicotinamide adenine dinucleotide (NAD+) with age and the supplementation of NAD+ precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), in combination with other geroprotective compounds, to restore NAD+ levels present in youth.”
NAD #NMN #geroprotective
Sharma A, Chabloz S, Lapides RA, Roider E, Ewald CY. Potential Synergistic Supplementation of NAD+ Promoting Compounds as a Strategy for Increasing Healthspan. Nutrients. 2023; 15(2):445. https://doi.org/10.3390/nu15020445
Aging, longevity, supplements, geroprotectors, SIRT1, NAD+, NMN, resveratrol, nutraceuticals, age-related diseases, flavonoids, senolytic, healthspan, EGCG, COQ10, Lycopene, Astaxanthin, Apigenein, luteolin, pterostilbene, betaine, quercetin, fisten, pronounce, CD38, PARP1, optimization, geroprotective
Optimizing Longevity with NAD+ Boosters #NMN #NR #geroprotector #longevity #SIRT #CD38 #astaxanthin #lycopene #quercitin #EGCG #pterostilbene #PARP1
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“Curcumin seems to preserve, and even repair, damaged tendons. In this systematic review, we focus more especially on the benefits of curcumin.”
curcumin #tendon #tendinopathy
Córdova A, Drobnic F, Noriega-González D, Caballero-García A, Roche E, Alvarez-Mon M. Is Curcumine Useful in the Treatment and Prevention of the Tendinopathy and Myotendinous Junction Injury? A Scoping Review. Nutrients. 2023; 15(2):384. https://doi.org/10.3390/nu15020384
Curcumin, tendon, tendinopathy, collagen, type 1, inflammation, substance p, Curcuma longa, Myotendinous Junction Injury, prevention, repair, regeneration, leukocytes, Curcumine, crosslinking, antialgic
Curcumin, Tendinopathy and Myotendinous Junction Injury Episode 1120 JAN 2023 #curcumin #tendon #tendinopathy #myotendinous #repair #regeneration
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“Curcumin seems to preserve, and even repair, damaged tendons. In this systematic review, we focus more especially on the benefits of curcumin.”
curcumin #tendon #tendinopathy
Córdova A, Drobnic F, Noriega-González D, Caballero-García A, Roche E, Alvarez-Mon M. Is Curcumine Useful in the Treatment and Prevention of the Tendinopathy and Myotendinous Junction Injury? A Scoping Review. Nutrients. 2023; 15(2):384. https://doi.org/10.3390/nu15020384
Curcumin, tendon, tendinopathy, collagen, type 1, inflammation, substance p, Curcuma longa, Myotendinous Junction Injury, prevention, repair, regeneration, leukocytes, Curcumine, crosslinking, antialgic
Curcumin, Tendinopathy and Myotendinous Junction Injury Episode 1120 JAN 2023 #curcumin #tendon #tendinopathy #myotendinous #repair #regeneration
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Brazilian Propolis Lean Muscle Mass and Body Fat Loss Episode 1119 JAN 2023
Taken together, a lower fat mass, as observed in this study, may be accounted for by a higher lipolytic capacity in adipocytes and skeletal muscles. In addition, another possible explanation for reduced fat mass may be attributed to the positive effect of propolis on skeletal muscle mass, resulting in increased energy expenditure through the basal metabolic rate.
propolis #lean muscle #fatloss
Kanazashi, M.; Iida, T.; Nakanishi, R.; Tanaka, M.; Ikeda, H.; Takamiya, N.; Maeshige, N.; Kondo, H.; Nishigami, T.; Harada, T.; Fujino, H. Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial. Nutrients 2023, 15, 364. https://doi.org/10.3390/nu15020364
Propolis, Artepillin C, brown fat, skeletal muscle, lean muscle, fat loss, metabolism, green propolis, Brazilian green propolis, adipocytes, peroxisome proliferator-activated receptor, AMPK, PPARγ, activated protein kinase, diet, elderly, fragile
Brazilian Propolis Lean Muscle Mass and Body Fat Loss #propolis #greenpropolis #leanmuscle #metabolism #leanbodymass #elderly #brownfat #artepillin
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Brazilian Propolis Lean Muscle Mass and Body Fat Loss Episode 1119 JAN 2023
Taken together, a lower fat mass, as observed in this study, may be accounted for by a higher lipolytic capacity in adipocytes and skeletal muscles. In addition, another possible explanation for reduced fat mass may be attributed to the positive effect of propolis on skeletal muscle mass, resulting in increased energy expenditure through the basal metabolic rate.
propolis #lean muscle #fatloss
Kanazashi, M.; Iida, T.; Nakanishi, R.; Tanaka, M.; Ikeda, H.; Takamiya, N.; Maeshige, N.; Kondo, H.; Nishigami, T.; Harada, T.; Fujino, H. Brazilian Propolis Intake Decreases Body Fat Mass and Oxidative Stress in Community-Dwelling Elderly Females: A Randomized Placebo-Controlled Trial. Nutrients 2023, 15, 364. https://doi.org/10.3390/nu15020364
Propolis, Artepillin C, brown fat, skeletal muscle, lean muscle, fat loss, metabolism, green propolis, Brazilian green propolis, adipocytes, peroxisome proliferator-activated receptor, AMPK, PPARγ, activated protein kinase, diet, elderly, fragile
Brazilian Propolis Lean Muscle Mass and Body Fat Loss #propolis #greenpropolis #leanmuscle #metabolism #leanbodymass #elderly #brownfat #artepillin
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Natural Compounds and Radiation InjuryThe aim of this review is to describe the most recent evidence on radiation-induced injury and the emerging protective role of natural compounds in preventing and treating this specific damage without compromising treatment efficacy.#radiation #mucositis, #naturalAltomare, A.; Fiore, M.; D’Ercole, G.; Imperia, E.; Nicolosi, R.M.; Della Posta, S.; Pasqua, G.; Cicala, M.; De Gara, L.; Ramella, S.; Guarino, M.P.L. Protective Role of Natural Compounds under Radiation-Induced Injury. Nutrients 2022, 14, 5374. https://doi.org/10.3390/nu14245374Radiation, Protective Compounds, Protective Plant Compounds, Natural, Ionizing radiation. ROS, Mucositis, radiotherapy induced mucositis, gamma radiation exposure, DNA, propolis, lutein, quercetin, egcg, rosmarinic acid, Chlorogenic Acid, Cinnamic Acid, Gallic Acid, reactive oxygen species, radiation exposure, radiation illness
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Natural Compounds and Radiation InjuryThe aim of this review is to describe the most recent evidence on radiation-induced injury and the emerging protective role of natural compounds in preventing and treating this specific damage without compromising treatment efficacy.#radiation #mucositis, #naturalAltomare, A.; Fiore, M.; D’Ercole, G.; Imperia, E.; Nicolosi, R.M.; Della Posta, S.; Pasqua, G.; Cicala, M.; De Gara, L.; Ramella, S.; Guarino, M.P.L. Protective Role of Natural Compounds under Radiation-Induced Injury. Nutrients 2022, 14, 5374. https://doi.org/10.3390/nu14245374Radiation, Protective Compounds, Protective Plant Compounds, Natural, Ionizing radiation. ROS, Mucositis, radiotherapy induced mucositis, gamma radiation exposure, DNA, propolis, lutein, quercetin, egcg, rosmarinic acid, Chlorogenic Acid, Cinnamic Acid, Gallic Acid, reactive oxygen species, radiation exposure, radiation illness
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Lactoferrin anti-viral powerhouse Episode 1117 JAN 2023
Although LF has several biological benefits, the host-protective effects against pathogens including viruses, bacteria, and fungi are regarded as one of its most beneficial [83]. Several reviews have highlighted the in vitro anti-viral effects of LF against pathogens that cause common infections such as influenza, the common cold, summer cold, gastroenteritis, polio, and herpes.
antiviral #lactoferrin #antimicrobial
Einerhand, A.W.C.; van Loo-Bouwman, C.A.; Weiss, G.A.; Wang, C.; Ba, G.; Fan, Q.; He, B.; Smit, G. Can Lactoferrin, a Natural Mammalian Milk Protein, Assist in the Battle against COVID-19? Nutrients 2022, 14, 5274. https://doi.org/10.3390/nu14245274
Lactoferrin, anti-viral, anti-microbial, iron-binding, immunomodulatory, microbiota-modulatory, covid, sars, B-cell differentiation, total T-cell activation, T-helper cell activation, cytotoxic T-cell activation, SARS-CoV-2, influenza, the common cold, summer cold, gastroenteritis, polio, herpes, iron binding
Lactoferrin anti-viral powerhouse #lactoferrin #sarscov2 #antiviral #antimicrobial #covid19 #nutraceutical #bovine#polio #herpes #commoncold#influenza
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Lactoferrin anti-viral powerhouse Episode 1117 JAN 2023
Although LF has several biological benefits, the host-protective effects against pathogens including viruses, bacteria, and fungi are regarded as one of its most beneficial [83]. Several reviews have highlighted the in vitro anti-viral effects of LF against pathogens that cause common infections such as influenza, the common cold, summer cold, gastroenteritis, polio, and herpes.
antiviral #lactoferrin #antimicrobial
Einerhand, A.W.C.; van Loo-Bouwman, C.A.; Weiss, G.A.; Wang, C.; Ba, G.; Fan, Q.; He, B.; Smit, G. Can Lactoferrin, a Natural Mammalian Milk Protein, Assist in the Battle against COVID-19? Nutrients 2022, 14, 5274. https://doi.org/10.3390/nu14245274
Lactoferrin, anti-viral, anti-microbial, iron-binding, immunomodulatory, microbiota-modulatory, covid, sars, B-cell differentiation, total T-cell activation, T-helper cell activation, cytotoxic T-cell activation, SARS-CoV-2, influenza, the common cold, summer cold, gastroenteritis, polio, herpes, iron binding
Lactoferrin anti-viral powerhouse #lactoferrin #sarscov2 #antiviral #antimicrobial #covid19 #nutraceutical #bovine#polio #herpes #commoncold#influenza
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BB68S significantly improved subjects’ cognitive functions (total RBANS score increased by 18.89 points after intervention, p less than 0.0001), especially immediate memory, visuospatial/constructional, attention, and delayed memory domains. BB68S intervention increased the relative abundances of beneficial bacteria Lachnospira, Bifidobacterium, Dorea, and Cellulosilyticum, while decreasing those of bacteria related to cognition impairment, such as Collinsella, Parabacteroides, Tyzzerella, Bilophila, unclassified_c_Negativicutes, Epulopiscium, Porphyromonas, and Granulicatella.
BifidobacteriumlongumBB68S #memory #probiotic
Shi, S.; Zhang, Q.; Sang, Y.; Ge, S.; Wang, Q.; Wang, R.; He, J. Probiotic Bifidobacterium longum BB68S Improves Cognitive Functions in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 2023, 15, 51. https://doi.org/10.3390/nu15010051
Bifidobacterium longum BB68S, RBANS, Cognition, immediate memory, visuospatial, attention, delayed memory, Repeatable Battery for the Assessment of Neuropsychological Status, human enhancement, memory enhancement, probiotic intervention, microbiota, Cognitive Functions
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Bifidobacterium longum BB68S Cognition Enhancement Super Star Episode #1116 DEC 2022
BB68S significantly improved subjects’ cognitive functions (total RBANS score increased by 18.89 points after intervention, p less than 0.0001), especially immediate memory, visuospatial/constructional, attention, and delayed memory domains. BB68S intervention increased the relative abundances of beneficial bacteria Lachnospira, Bifidobacterium, Dorea, and Cellulosilyticum, while decreasing those of bacteria related to cognition impairment, such as Collinsella, Parabacteroides, Tyzzerella, Bilophila, unclassified_c_Negativicutes, Epulopiscium, Porphyromonas, and Granulicatella.
BifidobacteriumlongumBB68S #memory #probiotic
Shi, S.; Zhang, Q.; Sang, Y.; Ge, S.; Wang, Q.; Wang, R.; He, J. Probiotic Bifidobacterium longum BB68S Improves Cognitive Functions in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients 2023, 15, 51. https://doi.org/10.3390/nu15010051
Bifidobacterium longum BB68S, RBANS, Cognition, immediate memory, visuospatial, attention, delayed memory, Repeatable Battery for the Assessment of Neuropsychological Status, human enhancement, memory enhancement, probiotic intervention, microbiota, Cognitive Functions
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Time-restricted Eating for the Prevention and Management of Metabolic Diseases
In pilot human studies, TRE with or without explicit calorie reduction can reduce body weight, glucose intolerance, hypertension, and dyslipidemia.
Manoogian ENC, Chow LS, Taub PR, Laferrère B, Panda S. Time-restricted Eating for the Prevention and Management of Metabolic Diseases. Endocr Rev. 2022 Mar 9;43(2):405-436. doi: 10.1210/endrev/bnab027. PMID: 34550357; PMCID: PMC8905332.
TRE #Timerestrictedeating #melatonin
Intermittent fasting may reverse type 2 diabetes, according to study
The researchers conducted a 3-month intermittent fasting diet intervention among 36 people with diabetes and found almost 90% of participants, including those who took blood sugar-lowering agents and insulin, reduced their diabetes medication intake after intermittent fasting. Fifty-five percent of these people experienced diabetes remission, discontinued their diabetes medication and maintained it for at least one year.
Xiao Yang, Jiali Zhou, Huige Shao, Bi Huang, Xincong Kang, Ruiyu Wu, Fangzhou Bian, Minghai Hu, Dongbo Liu, Effect of an Intermittent Calorie-restricted Diet on Type 2 Diabetes Remission: A Randomized Controlled Trial, The Journal of Clinical Endocrinology & Metabolism, 2022;, dgac661, https://doi.org/10.1210/clinem/dgac661
TRE, CMNT, Time restricted eating, time restricted feeding, reduce body weight, glucose intolerance, hypertension, dyslipidemia, diet, intermittent fasting, diabetes, blood sugar, type 2, Chinese Medical Nutrition Therapy, melatonin, circadian rhythm, metabolic diseases, cardiac health, heart health, sleep cycles, best time to eat
--- Support this podcast: https://anchor.fm/ralph-turchiano/support
Time-restricted Eating for the Prevention and Management of Metabolic Diseases
In pilot human studies, TRE with or without explicit calorie reduction can reduce body weight, glucose intolerance, hypertension, and dyslipidemia.
Manoogian ENC, Chow LS, Taub PR, Laferrère B, Panda S. Time-restricted Eating for the Prevention and Management of Metabolic Diseases. Endocr Rev. 2022 Mar 9;43(2):405-436. doi: 10.1210/endrev/bnab027. PMID: 34550357; PMCID: PMC8905332.
TRE #Timerestrictedeating #melatonin
Intermittent fasting may reverse type 2 diabetes, according to study
The researchers conducted a 3-month intermittent fasting diet intervention among 36 people with diabetes and found almost 90% of participants, including those who took blood sugar-lowering agents and insulin, reduced their diabetes medication intake after intermittent fasting. Fifty-five percent of these people experienced diabetes remission, discontinued their diabetes medication and maintained it for at least one year.
Xiao Yang, Jiali Zhou, Huige Shao, Bi Huang, Xincong Kang, Ruiyu Wu, Fangzhou Bian, Minghai Hu, Dongbo Liu, Effect of an Intermittent Calorie-restricted Diet on Type 2 Diabetes Remission: A Randomized Controlled Trial, The Journal of Clinical Endocrinology & Metabolism, 2022;, dgac661, https://doi.org/10.1210/clinem/dgac661
TRE, CMNT, Time restricted eating, time restricted feeding, reduce body weight, glucose intolerance, hypertension, dyslipidemia, diet, intermittent fasting, diabetes, blood sugar, type 2, Chinese Medical Nutrition Therapy, melatonin, circadian rhythm, metabolic diseases, cardiac health, heart health, sleep cycles, best time to eat
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“The data are thrilling,” said Jordan Karp, MD, professor and chair of the College of Medicine – Tucson’s Department of Psychiatry. “This nonpharmacological intervention is a promising life-changing and life-saving possibility for people suffering from PTSD.”
John R. Vanuk, Edward F. Pace-Schott, Ayla Bullock, Simon Esbit, Natalie S. Dailey, William D. S. Killgore. Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder. Frontiers in Behavioral Neuroscience, 2022; 16 DOI: 10.3389/fnbeh.2022.886816
BLT #Bluelight #PTSD
Blue light, 469nm, ptsd, fear extinction, sleep, fear expression, morning light, therapy, post-traumatic stress disorder. Bly, trauma, post-traumatic stress disorder, circadian rhythm
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“The data are thrilling,” said Jordan Karp, MD, professor and chair of the College of Medicine – Tucson’s Department of Psychiatry. “This nonpharmacological intervention is a promising life-changing and life-saving possibility for people suffering from PTSD.”
John R. Vanuk, Edward F. Pace-Schott, Ayla Bullock, Simon Esbit, Natalie S. Dailey, William D. S. Killgore. Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder. Frontiers in Behavioral Neuroscience, 2022; 16 DOI: 10.3389/fnbeh.2022.886816
BLT #Bluelight #PTSD
Blue light, 469nm, ptsd, fear extinction, sleep, fear expression, morning light, therapy, post-traumatic stress disorder. Bly, trauma, post-traumatic stress disorder, circadian rhythm
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Fat Loss and the New Green Med Diet Episode 1113 Fall 2022
The green Mediterranean diet (MED) significantly reduces visceral adipose tissue, a type of fat around internal organs that is much more dangerous than the extra "tire" around your waist. The green Mediterranean diet was pitted against the Mediterranean diet and a healthy diet in a large-scale clinical interventional trial- the DIRECT PLUS. Subsequent analysis found that the green Med diet reduced visceral fat by 14%, the Med diet by 7% and the healthy diet by 4.5%. The study was published in BMC Medicine.
VAT #duckweed #diet
Zelicha, H., Kloting, N., Kaplan, A. et al. The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial. BMC Med 20, 327 (2022). https://doi.org/10.1186/s12916-022-02525-8
Urolithin A, duckweed, VAT, visceral fat tissue, Subcutaneous adipose tissue, visceral adipose tissue, green med diet, Mediterranean diet, waist circumference, polyphenol, Mankai, Wolffia globose, green tea, SAT, green Mediterranean diet, fat loss, heart health
--- Support this podcast: https://anchor.fm/ralph-turchiano/support
The green Mediterranean diet (MED) significantly reduces visceral adipose tissue, a type of fat around internal organs that is much more dangerous than the extra "tire" around your waist. The green Mediterranean diet was pitted against the Mediterranean diet and a healthy diet in a large-scale clinical interventional trial- the DIRECT PLUS. Subsequent analysis found that the green Med diet reduced visceral fat by 14%, the Med diet by 7% and the healthy diet by 4.5%. The study was published in BMC Medicine.
VAT #duckweed #diet
Zelicha, H., Kloting, N., Kaplan, A. et al. The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial. BMC Med 20, 327 (2022). https://doi.org/10.1186/s12916-022-02525-8
Urolithin A, duckweed, VAT, visceral fat tissue, Subcutaneous adipose tissue, visceral adipose tissue, green med diet, Mediterranean diet, waist circumference, polyphenol, Mankai, Wolffia globose, green tea, SAT, green Mediterranean diet, fat loss, heart health
--- Support this podcast: https://anchor.fm/ralph-turchiano/support
l-arginine plus vitamin C supplementation improved walking performance, muscle strength, endothelial function, and fatigue in adults with long COVID. This supplement may, therefore, be considered to restore physical performance and relieve persistent symptoms in this patient population.
longcovid #arginine #fatigue
Tosato M, Calvani R, Picca A, Ciciarello F, Galluzzo V, Coelho-Júnior HJ, Di Giorgio A, Di Mario C, Gervasoni J, Gremese E, Leone PM, Nesci A, Paglionico AM, Santoliquido A, Santoro L, Santucci L, Tolusso B, Urbani A, Marini F, Marzetti E, Landi F on behalf of the Gemelli against COVID-19 Post-Acute Care Team. Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial. Nutrients. 2022; 14(23):4984. https://doi.org/10.3390/nu14234984
Long covid, fatigue, arginine, liposomal c, vitamin c, recovery, post-acute COVID-19 syndrome, SARS-CoV-2, 6 min walk test, handgrip strength, flow-mediated dilation, nitric oxide, nutraceuticals, oral supplement, persistent symptoms
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Long Covid Fatigue L-Arginine Liposomal C
l-arginine plus vitamin C supplementation improved walking performance, muscle strength, endothelial function, and fatigue in adults with long COVID. This supplement may, therefore, be considered to restore physical performance and relieve persistent symptoms in this patient population.
longcovid #arginine #fatigue
Tosato M, Calvani R, Picca A, Ciciarello F, Galluzzo V, Coelho-Júnior HJ, Di Giorgio A, Di Mario C, Gervasoni J, Gremese E, Leone PM, Nesci A, Paglionico AM, Santoliquido A, Santoro L, Santucci L, Tolusso B, Urbani A, Marini F, Marzetti E, Landi F on behalf of the Gemelli against COVID-19 Post-Acute Care Team. Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial. Nutrients. 2022; 14(23):4984. https://doi.org/10.3390/nu14234984
Long covid, fatigue, arginine, liposomal c, vitamin c, recovery, post-acute COVID-19 syndrome, SARS-CoV-2, 6 min walk test, handgrip strength, flow-mediated dilation, nitric oxide, nutraceuticals, oral supplement, persistent symptoms
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Hibiscus Tea Flavonoid may beat Alzheimer's disease Episode 1111 Fall 2022
“The research team treated AD model mice with gossypetin through intragastric administration for three months and concluded that their impaired memory and cognition were almost restored to the normal level. (13wk) Furthermore, they saw a decrease in the various types of Aβ aggregates, which are commonly found in the brain tissue with AD-type dementia.
gossypetin #hibiscus #alzheimers
Kyung Won Jo, Dohyun Lee, Dong Gon Cha, Eunji Oh, Yoon Ha Choi, Somi Kim, Eun Seo Park, Jong Kyoung Kim, Kyong-Tai Kim. Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ. Alzheimer's Research & Therapy, 2022; 14 (1) DOI: 10.1186/s13195-022-01096-3
Hibiscus, gossypetin, amyloid, tau, flavonoid, alzheimers, microgila, phagocytes, dementia, amyloid-beta, Hibiscus sabdariffa, roselle, ruby red hibiscus, phagocytosis, cognitive decline, memory loss
Support this podcast: https://anchor.fm/ralph-turchiano/support
“The research team treated AD model mice with gossypetin through intragastric administration for three months and concluded that their impaired memory and cognition were almost restored to the normal level. (13wk) Furthermore, they saw a decrease in the various types of Aβ aggregates, which are commonly found in the brain tissue with AD-type dementia.
gossypetin #hibiscus #alzheimers
Kyung Won Jo, Dohyun Lee, Dong Gon Cha, Eunji Oh, Yoon Ha Choi, Somi Kim, Eun Seo Park, Jong Kyoung Kim, Kyong-Tai Kim. Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ. Alzheimer's Research & Therapy, 2022; 14 (1) DOI: 10.1186/s13195-022-01096-3
Hibiscus, gossypetin, amyloid, tau, flavonoid, alzheimers, microgila, phagocytes, dementia, amyloid-beta, Hibiscus sabdariffa, roselle, ruby red hibiscus, phagocytosis, cognitive decline, memory loss
Support this podcast: https://anchor.fm/ralph-turchiano/support
"Our study provides novel insights on how brain metabolism relates to behavior and puts forward nutritional interventions targeting key oxidative process as ideal interventions to facilitate effortful endurance," conclude the authors. The study's findings "suggest that improvement of accumbal antioxidant function may be a feasible approach to boost motivation."
#NAC #nucleusaccumbens #motivation
Eva Ramos-Fernández, Ioannis Zalachoras, Fiona Hollis, Laura Trovo, João Rodrigues, Alina Strasser, Olivia Zanoletti, Pascal Steiner, Nicolas Preitner, Lijing Xin, Simone Astori, Carmen Sandi. Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort. eLife, 2022; 11 DOI: 10.7554/eLife.77791
NAC, Nucleus Accumbens, motivation, effort , glutathione, N-acetylcysteine, oxidative stress, GSH, persistence, antioxidant, ros, brain, reward, accumbal GSH, behavior, NuAc, accumbal antioxidant, effortful endurance, nutritional interventions
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Motivation Increased With NAC / (GSH)
"Our study provides novel insights on how brain metabolism relates to behavior and puts forward nutritional interventions targeting key oxidative process as ideal interventions to facilitate effortful endurance," conclude the authors. The study's findings "suggest that improvement of accumbal antioxidant function may be a feasible approach to boost motivation."
#NAC #nucleusaccumbens #motivation
Eva Ramos-Fernández, Ioannis Zalachoras, Fiona Hollis, Laura Trovo, João Rodrigues, Alina Strasser, Olivia Zanoletti, Pascal Steiner, Nicolas Preitner, Lijing Xin, Simone Astori, Carmen Sandi. Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort. eLife, 2022; 11 DOI: 10.7554/eLife.77791
NAC, Nucleus Accumbens, motivation, effort , glutathione, N-acetylcysteine, oxidative stress, GSH, persistence, antioxidant, ros, brain, reward, accumbal GSH, behavior, NuAc, accumbal antioxidant, effortful endurance, nutritional interventions
Support this podcast: https://anchor.fm/ralph-turchiano/support
Wearing special green eyeglasses for several hours a day reduces pain-related anxiety and may help decrease the need for opioids to manage severe pain in fibromyalgia patients and possibly others who experience chronic pain, according to a study being presented at the ANESTHESIOLOGY® 2022 annual meeting.
#green #anxiety #fibromyalgia
Effects Of Light Induced Analgesia On Anxiety For Fibromyalgia Patients Padma Gulur, M.D., Mary Wright, MS, Amanda Nelli, M.D. Duke University, Chapel Hill, North Carolina, United States A2094 October 23, 2022 American Society of Anesthesiologists
https://www.medpagetoday.com/meetingcoverage/asa/101375
https://www.painnewsnetwork.org/s/A2094-Effects-Of-Light-Induced-Analgesia-On-Anxiety-For-Fibromyalgia-Patients.pdf
Green light, green glasses, fibromyalgia, anxiety, fear, opioid, pain, pain reduction, pain relief, chronic pain, pain control, green
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Green Glasses may reduce Fear based Anxiety and Opioid Use
Wearing special green eyeglasses for several hours a day reduces pain-related anxiety and may help decrease the need for opioids to manage severe pain in fibromyalgia patients and possibly others who experience chronic pain, according to a study being presented at the ANESTHESIOLOGY® 2022 annual meeting.
#green #anxiety #fibromyalgia
Effects Of Light Induced Analgesia On Anxiety For Fibromyalgia Patients Padma Gulur, M.D., Mary Wright, MS, Amanda Nelli, M.D. Duke University, Chapel Hill, North Carolina, United States A2094 October 23, 2022 American Society of Anesthesiologists
https://www.medpagetoday.com/meetingcoverage/asa/101375
https://www.painnewsnetwork.org/s/A2094-Effects-Of-Light-Induced-Analgesia-On-Anxiety-For-Fibromyalgia-Patients.pdf
Green light, green glasses, fibromyalgia, anxiety, fear, opioid, pain, pain reduction, pain relief, chronic pain, pain control, green
Support this podcast: https://anchor.fm/ralph-turchiano/support
AKG may increase exercise performance and muscle size Episode 1108 Fall 2022
Previous studies have shown that AKG plays biological functions such as regulating energy metabolism, promoting osteogenesis, improving immunity, and prolonging life span of animal organism
AKG #musclegrowth #muscleendurance
Jinping Yang, Guli Xu, Yiming Xu, Pei Luo, Yexian Yuan, Lin Yao, Jingjing Zhou, Yunlong Zhu, Ishwari Gyawali, Chang Xu, Jinlong Feng, Zewei Ma, Yuxian Zeng, Songbo Wang, Ping Gao, Canjun Zhu, Qingyan Jiang, Gang Shu, AKG/OXGR1 promotes skeletal muscle blood flow and metabolism by relaxing vascular smooth muscle, Life Metabolism, 2022;, loac026, https://doi.org/10.1093/lifemeta/loac026
TCA, AKG, α-Ketoglutarate, alpha Ketoglutarate, muscle mass, metabolism, . Oxoglutarate receptor, muscle aging, OXGR1, type 1, exercise performance, endurance hypertrophy , tricarboxylic acid cycle, nerve regulation, hormone secretion, blood flow, fat deposition, slow oxidizing, angiogenesis, muscle growth, muscle size, vascular perfusion, skeletal muscle, krebs, citric
Support this podcast: https://anchor.fm/ralph-turchiano/support
AKG may increase exercise performance and muscle size Episode 1108 Fall 2022
Previous studies have shown that AKG plays biological functions such as regulating energy metabolism, promoting osteogenesis, improving immunity, and prolonging life span of animal organism
AKG #musclegrowth #muscleendurance
Jinping Yang, Guli Xu, Yiming Xu, Pei Luo, Yexian Yuan, Lin Yao, Jingjing Zhou, Yunlong Zhu, Ishwari Gyawali, Chang Xu, Jinlong Feng, Zewei Ma, Yuxian Zeng, Songbo Wang, Ping Gao, Canjun Zhu, Qingyan Jiang, Gang Shu, AKG/OXGR1 promotes skeletal muscle blood flow and metabolism by relaxing vascular smooth muscle, Life Metabolism, 2022;, loac026, https://doi.org/10.1093/lifemeta/loac026
TCA, AKG, α-Ketoglutarate, alpha Ketoglutarate, muscle mass, metabolism, . Oxoglutarate receptor, muscle aging, OXGR1, type 1, exercise performance, endurance hypertrophy , tricarboxylic acid cycle, nerve regulation, hormone secretion, blood flow, fat deposition, slow oxidizing, angiogenesis, muscle growth, muscle size, vascular perfusion, skeletal muscle, krebs, citric
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Licorice Compounds and their Amazing Potential
GL Glycyrrhizin and its derivative, glycyrrhetinic acid ( GA , exhibit a wide range of activities to elicit their oncoprotective and oncotherapeutic effects. The effects range from inducing cell cycle arrest, inducing apoptosis, inhibiting invasion and metastasis, immunomodulation, attenuating the inflammatory microenvironment in cancer to antioxidants, sensitizing the tumor to other drugs, and protecting from conventional therapy side effects
licorice #Glycyrrhizin #glycyrrhetinicacid
Rifika Jain, Mohamed Ali Hussein, Shannon Pierce, Chad Martens, Preksha Shahagadkar, Gnanasekar Munirathinam, Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights,Pharmacological Research,Volume 178,2022,106138,ISSN 1043-6618, https://doi.org/10.1016/j.phrs.2022.106138.
Licorice, Glycyrrhizin, glycyrrhetinic, anti inflammatory, metastasis, immunomodulation, oncoprotective, oncotherapeutic, apoptosis, antioxidant, gza, gl, ga, Anti-estrogenic, chemotherapy,
Support this podcast: https://anchor.fm/ralph-turchiano/support
Licorice Compounds and their Amazing Potential
GL Glycyrrhizin and its derivative, glycyrrhetinic acid ( GA , exhibit a wide range of activities to elicit their oncoprotective and oncotherapeutic effects. The effects range from inducing cell cycle arrest, inducing apoptosis, inhibiting invasion and metastasis, immunomodulation, attenuating the inflammatory microenvironment in cancer to antioxidants, sensitizing the tumor to other drugs, and protecting from conventional therapy side effects
licorice #Glycyrrhizin #glycyrrhetinicacid
Rifika Jain, Mohamed Ali Hussein, Shannon Pierce, Chad Martens, Preksha Shahagadkar, Gnanasekar Munirathinam, Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights,Pharmacological Research,Volume 178,2022,106138,ISSN 1043-6618, https://doi.org/10.1016/j.phrs.2022.106138.
Licorice, Glycyrrhizin, glycyrrhetinic, anti inflammatory, metastasis, immunomodulation, oncoprotective, oncotherapeutic, apoptosis, antioxidant, gza, gl, ga, Anti-estrogenic, chemotherapy,
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Licorice Compounds and their Amazing Potential
GL Glycyrrhizin and its derivative, glycyrrhetinic acid ( GA , exhibit a wide range of activities to elicit their oncoprotective and oncotherapeutic effects. The effects range from inducing cell cycle arrest, inducing apoptosis, inhibiting invasion and metastasis, immunomodulation, attenuating the inflammatory microenvironment in cancer to antioxidants, sensitizing the tumor to other drugs, and protecting from conventional therapy side effects
licorice #Glycyrrhizin #glycyrrhetinicacid
Rifika Jain, Mohamed Ali Hussein, Shannon Pierce, Chad Martens, Preksha Shahagadkar, Gnanasekar Munirathinam, Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights,Pharmacological Research,Volume 178,2022,106138,ISSN 1043-6618, https://doi.org/10.1016/j.phrs.2022.106138.
Licorice, Glycyrrhizin, glycyrrhetinic, anti inflammatory, metastasis, immunomodulation, oncoprotective, oncotherapeutic, apoptosis, antioxidant, gza, gl, ga, Anti-estrogenic, chemotherapy,
Support this podcast: https://anchor.fm/ralph-turchiano/support
"Using a weighted blanket increased melatonin concentrations in saliva by about 30 percent”
melatonin #blanket #weightedblanket
Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743
Support this podcast: https://anchor.fm/ralph-turchiano/support
melatonin #blanket #weightedblanket
Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743
Support this podcast: https://anchor.fm/ralph-turchiano/support
"Using a weighted blanket increased melatonin concentrations in saliva by about 30 percent”
#melatonin #blanket #weightedblanket
Meth, E. M. S., Brandão, L. E. M., van Egmond, L. T., Xue, P., Grip, A., Wu, J., Adan, A., Andersson, F., Pacheco, A. P., Uvnäs-Moberg, K., Cedernaes, J., & Benedict, C. (2022). A weighted blanket increases pre-sleep salivary concentrations of melatonin in young, healthy adults. Journal of Sleep Research, e13743. https://doi.org/10.1111/jsr.13743
Support this podcast: https://anchor.fm/ralph-turchiano/support
Daikenchuto may protect the gut against inflammatory bowel disease
Researchers report on the effects of a common herbal remedy on inflammatory bowel disease. A new study shows that DKT -- an herbal medicine containing ginger, pepper, ginseng, and maltose -- reduced the severity of colitis in lab mice by preventing the loss of important gut bacteria and by increasing levels of immune cells in the colon that fight inflammation.
Daikenchuto #colitis #ibd
Zhengzheng Shi, Tadashi Takeuchi, Yumiko Nakanishi, Tamotsu Kato, Katharina Beck, Ritsu Nagata, Tomoko Kageyama, Ayumi Ito, Hiroshi Ohno, Naoko Satoh-Takayama. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Frontiers in Immunology, 2022; 13 DOI: 10.3389/fimmu.2022.903459
Daikenchuto, inflammatory bowel disease, IBD. Colitis, gut, kampo, Lactobacillaceae, Lactobacillus, microbiome, DKT, ginger, pepper, ginseng, propionate, scfa, short-chain fatty acid
Support this podcast: https://anchor.fm/ralph-turchiano/support
Daikenchuto may protect the gut against inflammatory bowel disease
Researchers report on the effects of a common herbal remedy on inflammatory bowel disease. A new study shows that DKT -- an herbal medicine containing ginger, pepper, ginseng, and maltose -- reduced the severity of colitis in lab mice by preventing the loss of important gut bacteria and by increasing levels of immune cells in the colon that fight inflammation.
Daikenchuto #colitis #ibd
Zhengzheng Shi, Tadashi Takeuchi, Yumiko Nakanishi, Tamotsu Kato, Katharina Beck, Ritsu Nagata, Tomoko Kageyama, Ayumi Ito, Hiroshi Ohno, Naoko Satoh-Takayama. A Japanese Herbal Formula, Daikenchuto, Alleviates Experimental Colitis by Reshaping Microbial Profiles and Enhancing Group 3 Innate Lymphoid Cells. Frontiers in Immunology, 2022; 13 DOI: 10.3389/fimmu.2022.903459
Daikenchuto, inflammatory bowel disease, IBD. Colitis, gut, kampo, Lactobacillaceae, Lactobacillus, microbiome, DKT, ginger, pepper, ginseng, propionate, scfa, short-chain fatty acid
Support this podcast: https://anchor.fm/ralph-turchiano/support
Guar Gum may be a potent Immune regulator
Diets high in guar gum, a common food additive and dietary fibre, limited inflammation and delayed the onset of multiple sclerosis (MS) symptoms in mice, according to new research by members of the University of British Columbia (UBC) Microbiology and Immunology department.
guargum #ms # neuroinflammation
Fettig NM, Robinson HG, Allanach JR, Davis KM, Simister RL, Wang EJ, Sharon AJ, Ye J, Popple SJ, Seo JH, Gibson DL, Crowe SA, Horwitz MS, Osborne LC. Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis. Cell Rep. 2022 Sep 13;40(11):111328. doi: 10.1016/j.celrep.2022.111328. PMID: 36103823.
Guar gum, fiber, fibre, autoimmune, neuroinflammation, th1, autoimmune encephalomyelitis, dietary fiber, microbiota, experimental autoimmune encephalomyelitis, EAE, multiple sclerosis, MS, CD4+ T cells
Support this podcast: https://anchor.fm/ralph-turchiano/support
Guar Gum may be a potent Immune regulator
Diets high in guar gum, a common food additive and dietary fibre, limited inflammation and delayed the onset of multiple sclerosis (MS) symptoms in mice, according to new research by members of the University of British Columbia (UBC) Microbiology and Immunology department.
guargum #ms # neuroinflammation
Fettig NM, Robinson HG, Allanach JR, Davis KM, Simister RL, Wang EJ, Sharon AJ, Ye J, Popple SJ, Seo JH, Gibson DL, Crowe SA, Horwitz MS, Osborne LC. Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis. Cell Rep. 2022 Sep 13;40(11):111328. doi: 10.1016/j.celrep.2022.111328. PMID: 36103823.
Guar gum, fiber, fibre, autoimmune, neuroinflammation, th1, autoimmune encephalomyelitis, dietary fiber, microbiota, experimental autoimmune encephalomyelitis, EAE, multiple sclerosis, MS, CD4+ T cells
Support this podcast: https://anchor.fm/ralph-turchiano/support
Folic acid treatment associated with decreased risk of suicide attempts
The study, published in JAMA Psychiatry on September 28th, used data from the health insurance claims of 866,586 patients and looked at the relationship between folic acid treatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm). Robert Gibbons, PhD, the Blum-Riese Professor of Biostatistics and Medicine at the University of Chicago, the lead author of the study~~,~~ is hopeful that these findings could improve suicide prevention efforts, especially because of how accessible folic acid is.
“There are no real side effects, it doesn’t cost a lot of money, you can get it without a prescription,” Gibbons said. “This could potentially save tens of thousands of lives.”
mentalhealth #folicacid #B9
Gibbons RD, Hur K, Lavigne JE, Mann JJ. Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults. JAMA Psychiatry. Published online September 28, 2022. doi:10.1001/jamapsychiatry.2022.2990
Self harm, folic acid, b9, folate, suicide attempts, psychiatry, suicide prevention, safe, suicide prevention efforts, save lives, mental health
Support this podcast: https://anchor.fm/ralph-turchiano/support
Folic acid treatment associated with decreased risk of suicide attempts
The study, published in JAMA Psychiatry on September 28th, used data from the health insurance claims of 866,586 patients and looked at the relationship between folic acid treatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm). Robert Gibbons, PhD, the Blum-Riese Professor of Biostatistics and Medicine at the University of Chicago, the lead author of the study~~,~~ is hopeful that these findings could improve suicide prevention efforts, especially because of how accessible folic acid is.
“There are no real side effects, it doesn’t cost a lot of money, you can get it without a prescription,” Gibbons said. “This could potentially save tens of thousands of lives.”
mentalhealth #folicacid #B9
Gibbons RD, Hur K, Lavigne JE, Mann JJ. Association Between Folic Acid Prescription Fills and Suicide Attempts and Intentional Self-harm Among Privately Insured US Adults. JAMA Psychiatry. Published online September 28, 2022. doi:10.1001/jamapsychiatry.2022.2990
Self harm, folic acid, b9, folate, suicide attempts, psychiatry, suicide prevention, safe, suicide prevention efforts, save lives, mental health
Support this podcast: https://anchor.fm/ralph-turchiano/support
Melatonin's Amazing Research Discoveries: Episode 1102 FALL 2022
Like vitamin D, melatonin is found throughout the body. Melatonin has been found in many tissues other than the pineal gland and gut mucosa, including the brain, retina, lens, cochlea, trachea, skin, liver, kidney, thyroid, pancreas, thymus, spleen, and reproductive tissues. It is present in nearly all bodily fluids:
melatonin #antioxidant #chronobiotic
Minich DM, Henning M, Darley C, Fahoum M, Schuler CB, Frame J. Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements. Nutrients. 2022; 14(19):3934. https://doi.org/10.3390/nu14193934
Melatonin, vitamin d, chronobiotic, enterochromaffin, hormone, pineal, gut, darkness deficiency, plant derived, immune-active agent, mitochondrial regulator, migraine, Alzheimer’s disease, multiple sclerosis, fertility, PCOS, lowering body temperature, sleep
Support this podcast: https://anchor.fm/ralph-turchiano/support
Melatonin's Amazing Research Discoveries: Episode 1102 FALL 2022
Like vitamin D, melatonin is found throughout the body. Melatonin has been found in many tissues other than the pineal gland and gut mucosa, including the brain, retina, lens, cochlea, trachea, skin, liver, kidney, thyroid, pancreas, thymus, spleen, and reproductive tissues. It is present in nearly all bodily fluids:
melatonin #antioxidant #chronobiotic
Minich DM, Henning M, Darley C, Fahoum M, Schuler CB, Frame J. Is Melatonin the “Next Vitamin D”?: A Review of Emerging Science, Clinical Uses, Safety, and Dietary Supplements. Nutrients. 2022; 14(19):3934. https://doi.org/10.3390/nu14193934
Melatonin, vitamin d, chronobiotic, enterochromaffin, hormone, pineal, gut, darkness deficiency, plant derived, immune-active agent, mitochondrial regulator, migraine, Alzheimer’s disease, multiple sclerosis, fertility, PCOS, lowering body temperature, sleep
Support this podcast: https://anchor.fm/ralph-turchiano/support
"We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls," says senior author Dr. Richard Schwartz, chair of the MCG Department of Emergency Medicine. "Both of those are pretty significant endpoints."
nasal #bakingsoda #iodine
Amy L Baxter, Kyle R Schwartz, Ryan W Johnson, Ann-Marie Kuchinski, Kevin M Swartout, Arni S R Srinivasa Rao, Robert W Gibson, Erica Cherian, Taylor Giller, Houlton Boomer, Matthew Lyon, Richard Schwartz. Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients. Ear, Nose & Throat Journal, 2022; 014556132211237 DOI: 10.1177/01455613221123737
bakingsoda #alkaline #iodine #nasalirrigation #coronavirus #saline
Baking soda, alkaline, iodine, nasal irrigation, coronavirus, saline, spike protein, isotonic, sars, sodium bicarbonate, mucous membrane, furin, virus, povidone-iodine, salt
Support this podcast: https://anchor.fm/ralph-turchiano/support
Twice-daily nasal irrigation reduces COVID-related illness, death, study finds
"We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls," says senior author Dr. Richard Schwartz, chair of the MCG Department of Emergency Medicine. "Both of those are pretty significant endpoints."
nasal #bakingsoda #iodine
Amy L Baxter, Kyle R Schwartz, Ryan W Johnson, Ann-Marie Kuchinski, Kevin M Swartout, Arni S R Srinivasa Rao, Robert W Gibson, Erica Cherian, Taylor Giller, Houlton Boomer, Matthew Lyon, Richard Schwartz. Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients. Ear, Nose & Throat Journal, 2022; 014556132211237 DOI: 10.1177/01455613221123737
bakingsoda #alkaline #iodine #nasalirrigation #coronavirus #saline
Baking soda, alkaline, iodine, nasal irrigation, coronavirus, saline, spike protein, isotonic, sars, sodium bicarbonate, mucous membrane, furin, virus, povidone-iodine, salt
Support this podcast: https://anchor.fm/ralph-turchiano/support
Spirulina may be a powerful Memory Treatment
The 12-week supplementation with SM70EE was shown to be valid and safe. Therefore, the significant findings of this study suggest that SM70EE supplementation in patients with MCI with memory disorders is safe and can play a role in the prevention and management of AD
spirulina #MCI #memory
Choi W-Y, Lee W-K, Kim T-H, Ryu Y-K, Park A, Lee Y-J, Heo S-J, Oh C, Chung Y-C, Kang D-H. The Effects of Spirulina maxima Extract on Memory Improvement in Those with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2022; 14(18):3714. https://doi.org/10.3390/nu1418371
Microalgae, cyanobacterium, Spirulina, Spirulina maxima, memory improvement, Alzheimer’s disease, functional food, mild cognitive impairment, MCI, visual learning, visual working memory
spirulina #MCI #memory #Microalgae #cyanobacterium #Alzheimers #food
Support this podcast: https://anchor.fm/ralph-turchiano/support
Spirulina may be a powerful Memory Treatment
The 12-week supplementation with SM70EE was shown to be valid and safe. Therefore, the significant findings of this study suggest that SM70EE supplementation in patients with MCI with memory disorders is safe and can play a role in the prevention and management of AD
spirulina #MCI #memory
Choi W-Y, Lee W-K, Kim T-H, Ryu Y-K, Park A, Lee Y-J, Heo S-J, Oh C, Chung Y-C, Kang D-H. The Effects of Spirulina maxima Extract on Memory Improvement in Those with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2022; 14(18):3714. https://doi.org/10.3390/nu1418371
Microalgae, cyanobacterium, Spirulina, Spirulina maxima, memory improvement, Alzheimer’s disease, functional food, mild cognitive impairment, MCI, visual learning, visual working memory
spirulina #MCI #memory #Microalgae #cyanobacterium #Alzheimers #food
Support this podcast: https://anchor.fm/ralph-turchiano/support
Lupus, Memory Loss and Cancer Breakthroughs
Lupus pill shows promise in mice; clinical trial underway
https://www.eurekalert.org/news-releases/960980#.YwejKjE4TUo.wordpress
“scientists report they have begun phase 2 clinical trials with a pill containing a compound that, in mice, not only prevents lupus-like symptoms, but also reverses signs of organ damage caused by the disease and prevents death.”
Can we reverse the effects of age related memory loss? Experts say yes
https://www.eurekalert.org/news-releases/963187
“and found that electrical brain stimulation for 20 minutes on four consecutive days can improve working memory and long-term memory in individuals 65 years and older for at least one month”
Cancer study: Major preventive effect from resistant starch in people with Lynch syndrome
https://www.sciencedaily.com/releases/2022/07/220725203606.htm
"We found that resistant starch reduces a range of cancers by over 60%.”
lupus #cancer #memory
Lupus, afimetoran, organ damage, working memory, long term memory, electrodes, electrical stimulation, novelose, resistant starch, cancer, cancer prevention, lynch syndrome, oesophageal, gastric, biliary tract, pancreatic, duodenum cancers.
Support this podcast: https://anchor.fm/ralph-turchiano/support
Lupus, Memory Loss and Cancer Breakthroughs
Lupus pill shows promise in mice; clinical trial underway
https://www.eurekalert.org/news-releases/960980#.YwejKjE4TUo.wordpress
“scientists report they have begun phase 2 clinical trials with a pill containing a compound that, in mice, not only prevents lupus-like symptoms, but also reverses signs of organ damage caused by the disease and prevents death.”
Can we reverse the effects of age related memory loss? Experts say yes
https://www.eurekalert.org/news-releases/963187
“and found that electrical brain stimulation for 20 minutes on four consecutive days can improve working memory and long-term memory in individuals 65 years and older for at least one month”
Cancer study: Major preventive effect from resistant starch in people with Lynch syndrome
https://www.sciencedaily.com/releases/2022/07/220725203606.htm
"We found that resistant starch reduces a range of cancers by over 60%.”
lupus #cancer #memory
Lupus, afimetoran, organ damage, working memory, long term memory, electrodes, electrical stimulation, novelose, resistant starch, cancer, cancer prevention, lynch syndrome, oesophageal, gastric, biliary tract, pancreatic, duodenum cancers.
Support this podcast: https://anchor.fm/ralph-turchiano/support
Grapes Have Astonishing Potential for Health and Longevity
Adding grapes to a high-fat diet also increased levels of antioxidant genes and delayed natural death. Acknowledging that it is not an exact science to translate years of lifespan from a mouse to a human, Pezzuto said that his best estimate is the change observed in the study would correspond to an additional 4-5 years in the life of a human.
grapes #longevity #NAFLD
Dave A, Park E-J, Kumar A, Parande F, Beyoğlu D, Idle JR, Pezzuto JM. Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet. Foods. 2022; 11(13):1984. https://doi.org/10.3390/foods11131984
Grapes, metabolic diseases, high-fat diet, RNA sequencing, nutrigenomics, nafld, life extension, life expectancy, glutathione, California table grapes, health, gene expression. Microbiome, hepatic oxidative stress, glucose uptake, liver health, energy metabolism
grapes #longevity #NAFLD #gene #microbiome #longevity #liver #glucose #energy #health
Support this podcast: https://anchor.fm/ralph-turchiano/support
Grapes Have Astonishing Potential for Health and Longevity
Adding grapes to a high-fat diet also increased levels of antioxidant genes and delayed natural death. Acknowledging that it is not an exact science to translate years of lifespan from a mouse to a human, Pezzuto said that his best estimate is the change observed in the study would correspond to an additional 4-5 years in the life of a human.
grapes #longevity #NAFLD
Dave A, Park E-J, Kumar A, Parande F, Beyoğlu D, Idle JR, Pezzuto JM. Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet. Foods. 2022; 11(13):1984. https://doi.org/10.3390/foods11131984
Grapes, metabolic diseases, high-fat diet, RNA sequencing, nutrigenomics, nafld, life extension, life expectancy, glutathione, California table grapes, health, gene expression. Microbiome, hepatic oxidative stress, glucose uptake, liver health, energy metabolism
grapes #longevity #NAFLD #gene #microbiome #longevity #liver #glucose #energy #health
Support this podcast: https://anchor.fm/ralph-turchiano/support
GlyNAC may reverse multiple hallmarks of aging
“This is the first randomized clinical trial of GlyNAC supplementation in older humans (*March 2021 was smaller and open label), and it found that a wide variety of age-associated abnormalities improved in older adults supplemented with GlyNAC, while no improvements were seen in those receiving placebo,” said corresponding author Dr. Rajagopal Sekhar, professor of medicine - endocrinology, diabetes and metabolism at Baylor.
Premranjan Kumar, PhD, Chun Liu, BS, James Suliburk, MD, Jean W Hsu, PhD, Raja Muthupillai, PhD, Farook Jahoor, PhD, Charles G Minard, PhD, George E Taffet, MD, Rajagopal V Sekhar, MD, Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial, The Journals of Gerontology: Series A, 2022;, glac135, https://doi.org/10.1093/gerona/glac135
GlyNAC #longevity #glutathione
GlyNAC, NAC, glycine, glutathione, N-Acetylcysteine, aging, longevity, n acetyl cysteine, celltrient, mitochondrial dysfunction, mitophagy, inflammation, insulin resistance, endothelial dysfunction, genomic damage, stem cell fatigue, cellular senescence, glutathione deficiency, gait, gait speed, Oxidative Stress, Physical Function
#GlyNAC #longevity#glutathione #nac #nacetylcysteine #aging #muscle #glycine
Support this podcast: https://anchor.fm/ralph-turchiano/support
GlyNAC may reverse multiple hallmarks of aging
“This is the first randomized clinical trial of GlyNAC supplementation in older humans (*March 2021 was smaller and open label), and it found that a wide variety of age-associated abnormalities improved in older adults supplemented with GlyNAC, while no improvements were seen in those receiving placebo,” said corresponding author Dr. Rajagopal Sekhar, professor of medicine - endocrinology, diabetes and metabolism at Baylor.
Premranjan Kumar, PhD, Chun Liu, BS, James Suliburk, MD, Jean W Hsu, PhD, Raja Muthupillai, PhD, Farook Jahoor, PhD, Charles G Minard, PhD, George E Taffet, MD, Rajagopal V Sekhar, MD, Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial, The Journals of Gerontology: Series A, 2022;, glac135, https://doi.org/10.1093/gerona/glac135
GlyNAC #longevity #glutathione
GlyNAC, NAC, glycine, glutathione, N-Acetylcysteine, aging, longevity, n acetyl cysteine, celltrient, mitochondrial dysfunction, mitophagy, inflammation, insulin resistance, endothelial dysfunction, genomic damage, stem cell fatigue, cellular senescence, glutathione deficiency, gait, gait speed, Oxidative Stress, Physical Function
#GlyNAC #longevity#glutathione #nac #nacetylcysteine #aging #muscle #glycine
Support this podcast: https://anchor.fm/ralph-turchiano/support
B vitamins can potentially be used to treat advanced NAFLD
"Our findings are both exciting and important because they suggest that a relatively inexpensive therapy, vitamin B12 and folic acid, could be used to prevent and/or delay the progression of NASH," said Dr Singh. "Additionally, serum and hepatic homocysteine levels could serve as a biomarker for NASH severity."
Madhulika Tripathi, Brijesh Kumar Singh, Jin Zhou, Keziah Tikno, Anissa Widjaja, Reddemma Sandireddy, Kabilesh Arul, Siti Aishah Binte Abdul Ghani, George Goh Boon Bee, Kiraely Adam Wong, Ho Jia Pei, Shamini Guna Shekeran, Rohit Anthony Sinha, Manvendra K. Singh, Stuart Alexander Cook, Ayako Suzuki, Teegan Reina Lim, Chang-Chuen Cheah, Jue Wang, Rui-Ping Xiao, Xiuqing Zhang, Pierce Kah Hoe Chow, Paul Michael Yen. Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing Syntaxin 17 homocysteinylation. Journal of Hepatology, 2022; DOI: 10.1016/j.jhep.2022.06.033
B12 #NAFLD #NASH
Homocysteine,Vitamin therapy,Syntaxin-17,Autophagy,Protein homocysteinylation,Non-alcoholic steatohepatitis (NASH),Fibrosis,B12,Folate. Folic acid, fatty liver, nafld, liver disease
Support this podcast: https://anchor.fm/ralph-turchiano/support
B vitamins can potentially be used to treat advanced NAFLD
"Our findings are both exciting and important because they suggest that a relatively inexpensive therapy, vitamin B12 and folic acid, could be used to prevent and/or delay the progression of NASH," said Dr Singh. "Additionally, serum and hepatic homocysteine levels could serve as a biomarker for NASH severity."
Madhulika Tripathi, Brijesh Kumar Singh, Jin Zhou, Keziah Tikno, Anissa Widjaja, Reddemma Sandireddy, Kabilesh Arul, Siti Aishah Binte Abdul Ghani, George Goh Boon Bee, Kiraely Adam Wong, Ho Jia Pei, Shamini Guna Shekeran, Rohit Anthony Sinha, Manvendra K. Singh, Stuart Alexander Cook, Ayako Suzuki, Teegan Reina Lim, Chang-Chuen Cheah, Jue Wang, Rui-Ping Xiao, Xiuqing Zhang, Pierce Kah Hoe Chow, Paul Michael Yen. Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing Syntaxin 17 homocysteinylation. Journal of Hepatology, 2022; DOI: 10.1016/j.jhep.2022.06.033
B12 #NAFLD #NASH
Homocysteine,Vitamin therapy,Syntaxin-17,Autophagy,Protein homocysteinylation,Non-alcoholic steatohepatitis (NASH),Fibrosis,B12,Folate. Folic acid, fatty liver, nafld, liver disease
Support this podcast: https://anchor.fm/ralph-turchiano/support
Leaky Gut and Blood Glucose Quickly Improved with Green Tea
“We did not attempt to cure metabolic syndrome with a one-month study,” he said. “But based on what we know about the causal factors behind metabolic syndrome, there is potential for green tea to be acting at least in part at the gut level to alleviate the risk for either developing it or reversing it if you already have metabolic syndrome.”
greentea #metabolicsyndrome #leakygut
Joanna Hodges, Min Zeng, Sisi Cao, Avinash Pokala, Shahabbedin Rezaei, Geoffrey Sasaki, Yael Vodovotz, Richard Bruno, Catechin-Rich Green Tea Extract Reduced Intestinal Inflammation and Fasting Glucose in Metabolic Syndrome and Healthy Adults: A Randomized, Controlled, Crossover Trial, Current Developments in Nutrition, Volume 6, Issue Supplement_1, June 2022, Page 981, https://doi.org/10.1093/cdn/nzac068.010
Green Tea Extract, Green tea, GTE, Leaky Gut, Blood Sugars, Blood Glucose , Mets, gut inflammation, intestinal inflammation, cardiometabolic disorders, catechins, Gut permeability, diabetes, insulin sensitivity,
greentea #metabolicsyndrome #leakygut #gte #mets #catechins #gte
Support this podcast: https://anchor.fm/ralph-turchiano/support
Leaky Gut and Blood Glucose Quickly Improved with Green Tea
“We did not attempt to cure metabolic syndrome with a one-month study,” he said. “But based on what we know about the causal factors behind metabolic syndrome, there is potential for green tea to be acting at least in part at the gut level to alleviate the risk for either developing it or reversing it if you already have metabolic syndrome.”
greentea #metabolicsyndrome #leakygut
Joanna Hodges, Min Zeng, Sisi Cao, Avinash Pokala, Shahabbedin Rezaei, Geoffrey Sasaki, Yael Vodovotz, Richard Bruno, Catechin-Rich Green Tea Extract Reduced Intestinal Inflammation and Fasting Glucose in Metabolic Syndrome and Healthy Adults: A Randomized, Controlled, Crossover Trial, Current Developments in Nutrition, Volume 6, Issue Supplement_1, June 2022, Page 981, https://doi.org/10.1093/cdn/nzac068.010
Green Tea Extract, Green tea, GTE, Leaky Gut, Blood Sugars, Blood Glucose , Mets, gut inflammation, intestinal inflammation, cardiometabolic disorders, catechins, Gut permeability, diabetes, insulin sensitivity,
greentea #metabolicsyndrome #leakygut #gte #mets #catechins #gte
Support this podcast: https://anchor.fm/ralph-turchiano/support
Markers of oxidative stress were analyzed in blood samples collected before and at the end of the intervention. One of the most interesting results was an increase of almost 20% in levels of the antioxidant enzyme superoxide dismutase (SOD) in the group that received taurine, compared with a decrease of 3.5% in the control group. As the authors explain, SOD protects cells against harmful reactions of the superoxide radical.
Abud GF, De Carvalho FG, Batitucci G, Travieso SG, Bueno Junior CR, Barbosa Junior F, Marchini JS, de Freitas EC. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70. Nutrition. 2022 Sep;101:111706. doi: 10.1016/j.nut.2022.111706. Epub 2022 Apr 22. PMID: 35700594.
taurine #antiaging #SOD
Taurine, sod, superoxide dismutase, free radicals, youth, aging, anti aging, malondialdehyde, lipid peroxidation, antioxidant, antiaging therapy, enzyme
Support this podcast: https://anchor.fm/ralph-turchiano/support
Markers of oxidative stress were analyzed in blood samples collected before and at the end of the intervention. One of the most interesting results was an increase of almost 20% in levels of the antioxidant enzyme superoxide dismutase (SOD) in the group that received taurine, compared with a decrease of 3.5% in the control group. As the authors explain, SOD protects cells against harmful reactions of the superoxide radical.
Abud GF, De Carvalho FG, Batitucci G, Travieso SG, Bueno Junior CR, Barbosa Junior F, Marchini JS, de Freitas EC. Taurine as a possible antiaging therapy: A controlled clinical trial on taurine antioxidant activity in women ages 55 to 70. Nutrition. 2022 Sep;101:111706. doi: 10.1016/j.nut.2022.111706. Epub 2022 Apr 22. PMID: 35700594.
taurine #antiaging #SOD
Taurine, sod, superoxide dismutase, free radicals, youth, aging, anti aging, malondialdehyde, lipid peroxidation, antioxidant, antiaging therapy, enzyme
Support this podcast: https://anchor.fm/ralph-turchiano/support
Acidic activated charcoal improved HFD-induced obesity and insulin resistance without any serious adverse effects. These beneficial effects were likely due to modulating lipid absorption and altered FA/BA metabolism.
Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Wang X, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N. Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice. Front Nutr. 2022 May 12;9:852767. doi: 10.3389/fnut.2022.852767. PMID: 35634388; PMCID: PMC9134190.
charcoal #diet #metabolism
Acidic activated charcoal, red pine, High fat diet, Ultra processed foods, adipose microinflammation, lipid absorption, Akamatsu tree, bile acids, insulin resistance, metabolism, body weight
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High Fat Diet Completely Suppressed by Acidic Activated Charcoal
Acidic activated charcoal improved HFD-induced obesity and insulin resistance without any serious adverse effects. These beneficial effects were likely due to modulating lipid absorption and altered FA/BA metabolism.
Zhang X, Diao P, Yokoyama H, Inoue Y, Tanabe K, Wang X, Hayashi C, Yokoyama T, Zhang Z, Hu X, Nakajima T, Kimura T, Nakayama J, Nakamuta M, Tanaka N. Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice. Front Nutr. 2022 May 12;9:852767. doi: 10.3389/fnut.2022.852767. PMID: 35634388; PMCID: PMC9134190.
charcoal #diet #metabolism
Acidic activated charcoal, red pine, High fat diet, Ultra processed foods, adipose microinflammation, lipid absorption, Akamatsu tree, bile acids, insulin resistance, metabolism, body weight
Support this podcast: https://anchor.fm/ralph-turchiano/support
Wound Healing Accelerated with Topical DIM
The phytochemical 3,3'-diindolylmethane (DIM) successfully broke down the biofilms protecting two different pathogens including Acinetobacter baumannii and pseudomonas aeruginosa– enabling their eradication 65% and 70% of the time, respectively. Combined with antibiotics, that number jumped to 94%.
Golberg K, Markus V, Kagan B-e, Barzanizan S, Yaniv K, Teralı K, Kramarsky-Winter E, Marks RS, Kushmaro A. Anti-Virulence Activity of 3,3′-Diindolylmethane (DIM): A Bioactive Cruciferous Phytochemical with Accelerated Wound Healing Benefits. Pharmaceutics. 2022; 14(5):967. https://doi.org/10.3390/pharmaceutics14050967
DIM #wounds #healing #ulcers
DIM, Wounds, Healing, ULCERS, BIOFILM, P. aeruginosa , Pseudomonas aeruginosa, Gram-negative pathogens, Phytochemicals, Antimicrobial , Acinetobacter baumannii, hospital infections, battlefield infections, A. baumannii, Diindolylmethane, acne, candida
Support this podcast: https://anchor.fm/ralph-turchiano/support
Wound Healing Accelerated with Topical DIM
The phytochemical 3,3'-diindolylmethane (DIM) successfully broke down the biofilms protecting two different pathogens including Acinetobacter baumannii and pseudomonas aeruginosa– enabling their eradication 65% and 70% of the time, respectively. Combined with antibiotics, that number jumped to 94%.
Golberg K, Markus V, Kagan B-e, Barzanizan S, Yaniv K, Teralı K, Kramarsky-Winter E, Marks RS, Kushmaro A. Anti-Virulence Activity of 3,3′-Diindolylmethane (DIM): A Bioactive Cruciferous Phytochemical with Accelerated Wound Healing Benefits. Pharmaceutics. 2022; 14(5):967. https://doi.org/10.3390/pharmaceutics14050967
DIM #wounds #healing #ulcers
DIM, Wounds, Healing, ULCERS, BIOFILM, P. aeruginosa , Pseudomonas aeruginosa, Gram-negative pathogens, Phytochemicals, Antimicrobial , Acinetobacter baumannii, hospital infections, battlefield infections, A. baumannii, Diindolylmethane, acne, candida
DIM, Wounds, Healing, ULCERS, BIOFILM, P. aeruginosa , Pseudomonas aeruginosa, Gram-negative pathogens, Phytochemicals, Antimicrobial , Acinetobacter baumannii, hospital infections, battlefield infections, A. baumannii, Diindolylmethane, acne, candida
Support this podcast: https://anchor.fm/ralph-turchiano/support
Muscle Fatigue Improved with Urolithin A
these results are still exciting because they demonstrate that just taking a supplement for a short duration actually improved muscle endurance. Fatigue resistance got better in the absence of exercise."
Sophia Liu, Davide D’Amico, Eric Shankland, Saakshi Bhayana, Jose M. Garcia, Patrick Aebischer, Chris Rinsch, Anurag Singh, David J. Marcinek. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults. JAMA Network Open, 2022; 5 (1): e2144279 DOI: 10.1001/jamanetworkopen.2021.44279
urolithinA #endurance #fatigue
Urolithin A, Fatigue, Muscle, CRP, Mitochondrial, acylcarnitines, maximum voluntary contraction, mitophagy, elderly, weakness, endurance,
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Muscle Fatigue Improved with Urolithin A
these results are still exciting because they demonstrate that just taking a supplement for a short duration actually improved muscle endurance. Fatigue resistance got better in the absence of exercise."
Sophia Liu, Davide D’Amico, Eric Shankland, Saakshi Bhayana, Jose M. Garcia, Patrick Aebischer, Chris Rinsch, Anurag Singh, David J. Marcinek. Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults. JAMA Network Open, 2022; 5 (1): e2144279 DOI: 10.1001/jamanetworkopen.2021.44279
urolithinA #endurance #fatigue
Urolithin A, Fatigue, Muscle, CRP, Mitochondrial, acylcarnitines, maximum voluntary contraction, mitophagy, elderly, weakness, endurance,
Support this podcast: https://anchor.fm/ralph-turchiano/support
AHCC shows promise in clearing HPV
Patients in the placebo group received a placebo for 12 months. The study found that 14 of 22 patients (63.6%) in the treatment arm became HPV-negative
AHCC® Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections Front. Oncol., 22 June 2022 | https://doi.org/10.3389/fonc.2022.881902
https://www.eurekalert.org/news-releases/956667#.YrUfbtgh65k.wordpress
HPV #AHCC #HumanPapillomavirus
HPV #AHCC #HumanPapillomavirus #lentinula #ifn #igg1 #nk #infection #mushroom #immune
human papillomavirus, HPV, AHCC, NEGATIVE, active hexose correlated compound, lentinula edodes mycelia, MUSHROOM, INFECTION, IMMUNE, ONCOLOGY, interferon alpha, interferon beta, IFN, interferon gamma, IFN, IgG1, T lymphocytes, natural killer cell levels, NK
Support this podcast: https://anchor.fm/ralph-turchiano/support
AHCC shows promise in clearing HPV
Patients in the placebo group received a placebo for 12 months. The study found that 14 of 22 patients (63.6%) in the treatment arm became HPV-negative
AHCC® Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections Front. Oncol., 22 June 2022 | https://doi.org/10.3389/fonc.2022.881902
https://www.eurekalert.org/news-releases/956667#.YrUfbtgh65k.wordpress
HPV #AHCC #HumanPapillomavirus
HPV #AHCC #HumanPapillomavirus #lentinula #ifn #igg1 #nk #infection #mushroom #immune
human papillomavirus, HPV, AHCC, NEGATIVE, active hexose correlated compound, lentinula edodes mycelia, MUSHROOM, INFECTION, IMMUNE, ONCOLOGY, interferon alpha, interferon beta, IFN, interferon gamma, IFN, IgG1, T lymphocytes, natural killer cell levels, NK
Support this podcast: https://anchor.fm/ralph-turchiano/support
Discoveries in Depression Autism Liver Aging and Athletic Performance
Your liver is just under three years old
An international team of scientists used retrospective radiocarbon birth dating to show that the human liver stays young throughout life and is on average less than three years old.
https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00171-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405471222001715%3Fshowall%3Dtrue
Drumming improves behaviour and brain function in autistic adolescents, scientists reveal
Drumming for 90 minutes each week helps autistic children overcome hyperactivity and attention deficit difficulties
https://www.pnas.org/doi/10.1073/pnas.2106244119
Good bacteria to tackle depression
Intestinal flora plays an important role in health – including mental health. Researchers from the University of Basel and the University Psychiatric Clinics Basel (UPK) have shown that probiotics can support the effect of antidepressants and help to alleviate depression.
Antibiotics wreak havoc on athletic performance -Knocking out gut bacteria deflates the will, ability to exercise
New research demonstrates that by killing essential gut bacteria, antibiotics ravage athletes' motivation and endurance. The UC Riverside-led mouse study suggests the microbiome is a big factor separating athletes from couch potatoes.
https://www.sciencedirect.com/science/article/pii/S0376635722000675?via%3Dihub
probiotocs #depression #endurance
Probiotics, autism, music, grey matter, gray matter, motivation, autism autistic, depression, mood, bacteria, microbiome, liver age, cell renewal, cell age, c14, carbon dating, drumming, drums, antibiotics, energy, fuel, glucose, gut brain axis, muscle
probiotocs #depression #endurance #exercise #microbiome #aging #cell #autism #mood #gutbrain #energy #bacteria #impulse
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Discoveries in Depression Autism Liver Aging and Athletic Performance
Your liver is just under three years old
An international team of scientists used retrospective radiocarbon birth dating to show that the human liver stays young throughout life and is on average less than three years old.
https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00171-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405471222001715%3Fshowall%3Dtrue
Drumming improves behaviour and brain function in autistic adolescents, scientists reveal
Drumming for 90 minutes each week helps autistic children overcome hyperactivity and attention deficit difficulties
https://www.pnas.org/doi/10.1073/pnas.2106244119
Good bacteria to tackle depression
Intestinal flora plays an important role in health – including mental health. Researchers from the University of Basel and the University Psychiatric Clinics Basel (UPK) have shown that probiotics can support the effect of antidepressants and help to alleviate depression.
Antibiotics wreak havoc on athletic performance -Knocking out gut bacteria deflates the will, ability to exercise
New research demonstrates that by killing essential gut bacteria, antibiotics ravage athletes' motivation and endurance. The UC Riverside-led mouse study suggests the microbiome is a big factor separating athletes from couch potatoes.
https://www.sciencedirect.com/science/article/pii/S0376635722000675?via%3Dihub
probiotocs #depression #endurance
Probiotics, autism, music, grey matter, gray matter, motivation, autism autistic, depression, mood, bacteria, microbiome, liver age, cell renewal, cell age, c14, carbon dating, drumming, drums, antibiotics, energy, fuel, glucose, gut brain axis, muscle
probiotocs #depression #endurance #exercise #microbiome #aging #cell #autism #mood #gutbrain #energy #bacteria #impulse
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Breakthroughs in DHA ZINC INULIN & D
Study shows people with a high omega-3 DHA level in their blood are at 49% lower risk of Alzheimer’s
https://www.mdpi.com/2072-6643/14/12/2408/htm
Zinc found to play an important role in lung fibrosis
https://www.jci.org/articles/view/157338
Dietary fibre in the gut may help with skin allergies: Monash study
https://www.nature.com/articles/s41385-022-00524-9
Vitamin D may restore the body’s natural barrier against ovarian cancer
https://www.sciencedirect.com/science/article/pii/S0945053X22000397?via%3Dihub
alzheimers #IPF #Ovarian
Alzheimer’s , Dementia, Memory, DHA, Fibrosis, IPF, idiopathic pulmonary fibrosis, zinc, zip8, lungs, Docosahexaenoic acid, omega, inulin, skin barrier, dust mites, butyrate, SCFA, Fiber, Vitamin D, Ovarian Cancer, allergic skin inflammation, skin barrier, fermentable, mesothelial cells, zinc transporter 8, peritoneal
alzheimers #IPF #Ovarian #DHA #fibrosis #zinc #inulin #VitaminD #zip8 #omega #cancer #skin #scfa #fiber #fibre #ovarian #allergies #lungs
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Study shows people with a high omega-3 DHA level in their blood are at 49% lower risk of Alzheimer’s
https://www.mdpi.com/2072-6643/14/12/2408/htm
Zinc found to play an important role in lung fibrosis
https://www.jci.org/articles/view/157338
Dietary fibre in the gut may help with skin allergies: Monash study
https://www.nature.com/articles/s41385-022-00524-9
Vitamin D may restore the body’s natural barrier against ovarian cancer
https://www.sciencedirect.com/science/article/pii/S0945053X22000397?via%3Dihub
alzheimers #IPF #Ovarian
Alzheimer’s , Dementia, Memory, DHA, Fibrosis, IPF, idiopathic pulmonary fibrosis, zinc, zip8, lungs, Docosahexaenoic acid, omega, inulin, skin barrier, dust mites, butyrate, SCFA, Fiber, Vitamin D, Ovarian Cancer, allergic skin inflammation, skin barrier, fermentable, mesothelial cells, zinc transporter 8, peritoneal
alzheimers #IPF #Ovarian #DHA #fibrosis #zinc #inulin #VitaminD #zip8 #omega #cancer #skin #scfa #fiber #fibre #ovarian #allergies #lungs
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Opioid use cut in Half with essential oils post-surgery
The researchers concluded: “Our results suggest that, by controlling anxiety, aromatherapy can help control pain and reduce opioid consumption. This is important, given the established role of the use of opioids in surgical patients in the overall opioid crisis in the US.”
opioid #aromatherapy #pain
Abstract 08AP02-05 at Euroanaesthesia, the annual meeting of the European Society of Anaesthesiology and Intensive Care (ESAIC)
Opioid, aromatherapy, peppermint, lavender, anxiety, surgery, pain killers, limbic system, pain reduction, anxious, calming, relaxing, therapy, essential oils, addiction, opiates
opioid #aromatherapy #pain #peppermint #lavender #pain #anxiety #essentialoils #opiates #addiction #relaxation
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How cranberries could improve memory and ward off dementia
Researchers have found that eating cranberries could improve memory, ward off dementia, and reduce 'bad' cholesterol. The research team studied the benefits of consuming the equivalent of a cup of cranberries a day among 50 to 80-year-olds. They hope that their findings could have implications for the prevention of neurodegenerative diseases such as dementia.
cranberries #memory #dementia
Emma Flanagan, Donnie Cameron, Rashed Sobhan, Chloe Wong, Matthew G. Pontifex, Nicole Tosi, Pedro Mena, Daniele Del Rio, Saber Sami, Arjan Narbad, Michael Müller, Michael Hornberger, David Vauzour. Chronic Consumption of Cranberries (Vaccinium macrocarpon) for 12 Weeks Improves Episodic Memory and Regional Brain Perfusion in Healthy Older Adults: A Randomised, Placebo-Controlled, Parallel-Groups Feasibility Study. Frontiers in Nutrition, 2022; 9 DOI: 10.3389/fnut.2022.849902
Cranberry, cranberries, polyphenols, memory, recall, dementia, ldl, nucleus accumbens, medial temporal, prefrontal, episodic memory, visual episodic memory, ), neural functioning, brain perfusion, oxygen, glucose, brain energy, Vaccinium macrocarpon
cranberries #memory #dementia #recall #polyphenol #perfusion #accumbens #episodic #temporal #Vacciniummacrocarpon #ldl
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Herbs for Tendons / Carpal Tunnel Syndrome
This review discusses the utility of herbal nutraceuticals that have demonstrated safety and tolerability as anti-inflammatory agents for the prevention and treatment of tendinitis through the suppression of catabolic signaling pathways
Mueller A-L, Brockmueller A, Kunnumakkara AB, Shakibaei M. Modulation of Inflammation by Plant-Derived Nutraceuticals in Tendinitis. Nutrients. 2022; 14(10):2030. https://doi.org/10.3390/nu14102030
Carpal tunnel syndrome, tendonitis, herb, phytochemicals, phytopharmaceuticals, inflammation, anti-inflammatory, echinacea, icariin, Epimedium grandiflorum, flavonoids, bromelain, curcumin, quercetin, egcg, green tea, genistein, avocado, resveratrol, polyphenols Achilles, rotator cuff, Boswellia serrata, tendinopathy, epicondylitis
tendons #tendonitis #herbs #carpal #phytochemicals #phytopharmaceuticals #inflammation #echinacea #icariin #Epimedium #flavonoids, #bromelain, #curcumin, #quercetin, #egcg #greentea, #genistein, #avocado, #resveratrol, #polyphenols #Boswellia #epicondylitis
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Circadian Caloric Reduction Increased Life Expectancy up to 35%
Victoria Acosta-Rodríguez, Filipa Rijo-Ferreira, Mariko Izumo, Pin Xu, Mary Wight-Carter, Carla B. Green, Joseph S. Takahashi. Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice. Science, 2022; DOI: 10.1126/science.abk0297
longevity #calories #circadian
Diet, fasting, circadian, longevity, lifespan, calorie restriction, life extension, internal clock, Effects of Reducing Intake of Energy, CALERIE, Circadian alignment, aging, gene expression
longevity #calories #circadian #fasting #aging #calories #activity #lifespan #timing
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These results indicated that 8C significantly improved cardiac function by approximately 40%.
Lei I, Tian S, Gao W, Liu L, Guo Y, Tang P, Chen E, Wang Z. Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation. Elife. 2021 Dec 23;10:e60311. doi: 10.7554/eLife.60311. PMID: 34939931; PMCID: PMC8763402.
heart #mct #heartattack
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Isoflavones found in plants are effective against dense tumor structures affecting human internal organs. For example, soy extract is most effective against metastases and malignant tumor cells developing in the muscles (rhabdomyosarcoma), while isoflavones from kudzu roots showed good anticarcinogenic effect against brain cancer (glioblastoma multiforme) and bone and connective tissue cancer (osteosarcoma). Studies were performed in vitro on cell lines of these diseases.
isoflavones #kudzu #cancer
Aboushanab SA, Shevyrin VA, Slesarev GP, Melekhin VV, Shcheglova AV, Makeev OG, Kovaleva EG, Kim KH. Antioxidant and Cytotoxic Activities of Kudzu Roots and Soy Molasses against Pediatric Tumors and Phytochemical Analysis of Isoflavones Using HPLC-DAD-ESI-HRMS. Plants. 2022; 11(6):741. https://doi.org/10.3390/plants11060741
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Vitamin K supplementation was associated with reduced evidence of cognitive impairment, depression and anxiety, along with improved spatial memory and learning ability.
Elkattawy HA, Ghoneim FM, Eladl MA, Said E, Ebrahim HA, El-Shafey M, Asseri SM, El-Sherbiny M, Alsalamah RH, Elsherbiny NM, Hadhod S. Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats. Antioxidants. 2022; 11(3):514. https://doi.org/10.3390/antiox11030514
k2 #depression #dementia
Vitamin k2, menaquinone-7, Dementia, Alzheimer’s, neuro inflammation, cognitive impairment, depression, anxiety, spatial memory, learning ability, NLRP3, caspase-1, Il-1β, TNFα, IL-6, CD68, k2, mk-7, frontal cortex, hippocampal
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A two-week course of high doses of CBD helps restore the function of two proteins key to reducing the accumulation of beta-amyloid plaque, a hallmark of Alzheimer's disease, and improves cognition in an experimental model of early onset familial Alzheimer's, investigators report.
alzheimer’s #CBD #plaque
Hesam Khodadadi, Évila Lopes Salles, Abbas Jarrahi, Vincenzo Costigliola, MB Khan, Jack C. Yu, John C. Morgan, David C. Hess, Kumar Vaibhav, Krishnan M. Dhandapani, Babak Baban. Cannabidiol Ameliorates Cognitive Function via Regulation of IL-33 and TREM2 Upregulation in a Murine Model of Alzheimer’s Disease. Journal of Alzheimer's Disease, 2021; 1 DOI: 10.3233/JAD-210026
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad210026
cbd, cannabidiol, Alzheimer's, familial Alzheimer's, plaque, beta amyloid, cognition, trem2, il-33, amyloid-beta, Triggering Receptor Expressed on Myeloid Cells 2, brain, cognitive, aging, accumulation, interlukin
trem2 #il33 #Alzheimers #cbd #cognition #plaque #amyloid #cannabidiol
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Who would have thought that a small basic compound like vitamin B6 in the banana or fish you had this morning may be key to your body's robust response against COVID-19? #B6 #vitaminB6 #cytokinestorm Thanutchaporn Kumrungsee et al, Potential Role of Vitamin B6 in Ameliorating the Severity of COVID-19 and Its Complications, Frontiers in Nutrition (2020). DOI: 10.3389/fnut.2020.562051
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Often used as an additive for cat toys and treats due to its euphoric and hallucinogenic effects on cats, catnip has also long been known for its powerful repellent action on insects, mosquitoes in particular. Recent research shows catnip compounds to be at least as effective as synthetic insect repellents such as DEET. #catnip #mosquito #insectrepellent N. Melo et al. The irritant receptor TRPA1 mediates the mosquito repellent effect of catnip. Current Biology. Published online March 4, 2021. doi: 10.1016/j.cub.2021.02.010.
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This episode is also available as a blog post: https://clinicalnews.org/2021/03/09/real-world-data-reveal-risks-of-allergic-reactions-after-receiving-covid-19-mrna-vaccines/
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This episode is also available as a blog post: https://clinicalnews.org/2021/03/09/breaking-the-warp-barrier-for-faster-than-light-travel/
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This episode is also available as a blog post: https://clinicalnews.org/2021/03/10/concerns-over-integrity-of-mrna-molecules-in-some-covid-19-vaccines/
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This episode is also available as a blog post: https://clinicalnews.org/2021/03/02/fair-health-releases-study-on-impact-of-covid-19-on-pediatric-mental-health/
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This episode is also available as a blog post: https://clinicalnews.org/2021/03/09/covid-19-risk-increases-with-airborne-pollen/
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