The Plunge: Recent Episodes

Mimi Ho, Mike Cianfrocco, and Liz Kellogg

A series of conversations hosted by Mimi Ho, Mike Cianfrocco, and Liz Kellogg. Mimi Mike & Liz discuss the past, present, and future of cryo-electron microscopy, a nobel prize winning technique which is used to study how life is organized at the atomic level. This first season includes established and new innovators who have pioneered astonishing new contributions to the field.

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Melody talks about our shared struggles starting labs during the pandemic, and how to build a cohesive group. We also talk about challenging cryo-EM targets, like integrins, and how the Campbell lab approaches them.

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Lisa talks about her recent successes and shares her tips for starting out in Cryo-EM, as well as her vision for the future. This episode is great for trainees looking to get started in this exciting field!

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Mark joins Mimi, Mike, and Liz to talk about his experience challenging cryo-EM paradigms, namely lower size limits for protein samples and using 'screening' microscopes for high-end data collection. We also talk about experiences of first-generation academics and the hidden 'rules' of academia. We also talk about the future of cryo-EM in terms of improving accessibility and access to resources.

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Ellen shares her journey into the world of cryo-EM and her excitement for the future of Machine Learning (ML) and structural biology. Mimi, Mike & Liz talk about being newcomers to a field and how to bridge disciplines by building community, like the Machine Learning in Structural Biology Workshop at NEURIPS 2022.