The Endpoint: A Clinical Trial Podcast: Recent Episodes
Liam Eves
Join me on my journey across the clinical trial landscape. I will be accompanied by a variety of people, all experts within their field, as we seek to understand and uncover unknowns, to shape ideas, inspire innovation and ultimately to find out how we can truly move clinical trials out of the spiralling void of higher costs and lower outputs. Click on an episode below to listen.
Sandy joins Liam on this week’s podcast episode. Sandy is the Vice President of Commercial Operations at MMS. Sandy has built an impressive career focused on strategic pricing across several prominent companies, including Syneos, PPD, Quintiles, and more. In our discussion today, we delve into a range of critical topics, including the distinction between price and value in the industry, what’s broken in the current trial model between sponsors, CROs, and sites, and why we shouldn’t rely on past pricing models to shape the future. Additionally, we explore Sandy's backstory on how she entered the clinical trials space, her unique process for helping groups demonstrate value over price, and much more.
Jeff joins Liam on this week’s podcast episode. Jeff is a seasoned executive within the pharma and CRO space. Jeff is currently the President at The Luna Group Consulting. He was previously the CEO of Alimentiv, in which he scaled it from an academic spin out to a specialised CRO focused on GI. In our discussion today we discuss all things CRO, we understand how the space works, the relationships amongst stakeholders, understand where the industry gets it right and wrong and take a deep dive on leadership and so much more.
Ted joins Liam on this week’s podcast episode. Ted is the Director of Business Development at Probity Medical Research. Probity Medical Research (PMR) is a leading clinical research consortium with over 70 clinical trials sites. PMR's network conducts clinical trials in Aesthetics, Allergy / Immunology, Cardiology, Dermatology, Rheumatology and Vaccines. In todays session we explore all things enrollment. We discuss the psychology at sites, how to create a high performing site, the relationships between site, CRO’s and Sponsors, investing in sites, and throw in a few stories and analogies for good measure!
Scott join Liam on this week’s podcast episode. Scott is VP and Global Head of Drug Development at Novotech. Founded in 1997, Novotech is a global full-service clinical Contract Research Organization (CRO) focused on partnering with biotech companies to accelerate the development of advanced and novel therapeutics at every phase. In todays session we explore Scott’s origin story, discuss it means to him to put patients first, dive into ways we can deliver trials differently and some of his biggest lessons learned over the years in the clinical trial space and much more!
Todays Guest is Kris Larson. Kris has 25+ years of global experience in brand development across a variety of sectors - including Life science. He is currently the Director of Client Engagement at Six Degrees. Six Degrees is a Psycho-Sensory Brand Building Agency. The company focuses on combining psychology-based tools and techniques with sensory branding methods to create real and lasting brand impact.
In this session we dive into understanding what psycho-sentory branding is and the value it has in clinical trials.
Jenn and Richie join Liam on this week’s podcast episode. Jenn and Richie are founders of Canary Advisors. Canary Advisors is a boutique consultancy that works with organizations on patient focused drug and device development. They work with biopharmaceutical, nonprofit, and regulatory groups to better understand disease impacts, unmet needs, and patient preferences. In todays session we discuss what patient advocacy is, where do Sponsors get it wrong and what we can do about it and understand the patient FDA process and much more.
Joel White joins Liam on this week’s podcast episode. Joel founded Marketcap Consulting, LLC in 2021 to help companies increase the valuation and effectiveness of their business by improving their financial performance and strategy. Prior to this he has worked with groups such as Synteract, Chiltern, Parexel, PRA. In todays session we discuss the current clinical trial landscape and economy, discuss how to price services and talk about current tension between CRO’s and sites and much more.
Vatche Bartekian joins Liam on this week’s podcast episode. Vatche is the Founder and President at Vantage BioTrials. Vantage BioTrials is a Canadian CRO that delivers clinical trial management services to clients in the pharmaceutical, biotechnology, and medical device sectors. Prior to this Vatche worked with groups such as Pfizer, Covance and PPD. In todays session we discuss about the concept of quality by design, how AI could support research and much more.
Vincent Cafiso joins Liam on this week’s podcast episode. Vin is the founder and Managing Consultant at Practical Compliance Results. It’s here that Vin helps medical device and IVD companies be ready for FDA inspection. In this session, we discuss a wide range of topics relating to compliance, quality assurance and quality systems. We discuss the principles of regulation and how companies can prepare for inspections and audits and much more.
Scott Whitt joins Liam on this week’s podcast episode. Scott is the President and General Manager of Triad Clinical Trials, a premier research clinic located in Greensboro, North Carolina that serves the Triad region. In this session, we discuss topics including Scott's journey from consulting for firms such as IQVIA, Deloitte, and United Health to buying a clinical research site. We explore the dynamic and kinetic world of research. We dive into how he and his team tripled Triad’s performance, discuss some misalignments with site and sponsor, and much more.
Tiffany Ashton joins Liam on this week’s podcast episode. Tiffany is the Director of Operations at ClinEssentials. ClinEssentials provides training and tools for Clinical Research Associates (CRA), Clinical Trial Managers (CTMs), and more. In this session, we explore a range of topics including Tiffany’s journey into clinical trials, some of the problems in clinical trials as a CTA and CTM, how you can solve them, considerations for Biotech and Pharma when operationalising their study, and much more
Dan Sfera joins Liam on this week’s podcast episode. Dan is Co-Founder of Yuma Clinical Trials. Yuma conduct multi-therapeutic clinical trials and align with clinicians and specialists to bring study opportunities to the underserved Southwestern Arizona region. Dan is also the Co-Founder of CRA Academy, and owner of The Clinical Trial Guru, where he shares his knowledge of clinical trials. In this session we explore a range of topics including, Dan’s journey into clinical trials, some of the problems of running a research centre and how he solves them and much more.
Stacy Hurt joins Liam on this week’s podcast episode. Stacy is the Chef Patient Officer (CPO) at Parexel. It’s one of the largest clinical research organizations (CROs) and provides the full range of Phase I to IV clinical development services to help life-saving treatments reach patients faster. In this session we explore a range of topics including, Stacy’s inspiring journey from caring for her son and battling cancer to becoming a patient advocate, along with other topics such as how in her new role as CPO she is leading the charge on helps Sponsors be more patient centric and much more.
Dr Jeff Kingsley joins Liam on this week’s podcast episode. Jeff is the CEO and founder of IACT Health, chair and COO and founding member of hyperCORE International, and the host of Riding in Cars with Researchers, a clinical trial podcast. IACT Health, is a research management organisation with 17 wholly owned and integrated clinical research offices throughout the Southeast US. Recently IACT has announced a strategic alliance with LMC Manna Research and have close to 40 wholly owned sites in US and Canada. In this session we explore frameworks for effective clinical trial delivery - E. Q. T. CS. How to run a successful site management business and much more. This is a masterclass in research at site.
Brad Hightower joins Liam on this week’s podcast episode. Brad is the CEO and founder of Hightower Clinical and the host of Note to File, a clinical trial podcast. Hightower Clinical is an integrated clinical trials company that works directly with physicians to unlock patients at site. In this session we discuss the ups and downs of operating trials at site, how the DCT movement is changing the landscape, how integrated care and research serves the patient and much more.
Liz Beatty joins Liam on this week’s podcast episode. Liz is the Chief Strategy Officer at Inato. Inato is a clinical trial marketplace that aims to create greater engagement across a more diverse population of doctors and patients. In this session we discuss a number of trends relating to sites, such as diversity, operating in a digital world, how the sites need a voice in clinical research and much more. We also explore some of the lessons Liz has learned over the years in a variety of different operational roles.
Kunal Sampat joins Liam on this week’s podcast episode. Kunal is a clinical coach & host of The Clinical Trial Podcast, he is also the director of operations at Ceribell, Inc. Kunal has a special interest in working with key opinion leaders and sites to boost recruitment in clinical trials. So inevitably we discuss our shared passion of patient recruitment, from different perspectives (both a site and sponsor), understand how sites can leverage workflows to optimise performance and much more.
Dan Hydes and Richard Yeatman join Liam on this week’s podcast episode. Dan (CEO) and Richard (CTO) are the co-founders of Ignite Data. Ignite Data is technology platform that reduces the burden of monitoring and source data verification. In our discussion we discuss the pains of monitoring and source data verification. Understand the barriers and impact it has on trials and most importantly what can be done to resolve it, plus much more.
Musaddiq Khan joins Liam on this week’s podcast episode. Muz is the Vice President, DCT Solutions at Medable. Medable is a technology platform that enables Sponsors to run Decentralised Clinical Trials. In our discussion we discuss the role of innovation in pharma, talk through how pharma thinks about innovation / digital technologies. Understand what impact tech has on clinical development? Is there a process for innovation? And much more.
The Endpoint Podcast: Episode 11 with Musaddiq Khan
Presented by Liam Eves
Bruce Hellman joins Liam on this week’s podcast episode. Bruce is CEO & Co-Founder of uMotif. uMotif is an eClinical data capture platform that patients love to use. The platform has been deployed in over 21 clinical clinical conditions. In our discussion we cover the impact of decentralised clinical trials, the challenges of remote data capture and how to overcome them. Human centred design - what is it? How can we use in the clinical trial space? And much more.
Ken Getz joins Liam on this week’s podcast episode. Ken is the Director, Research Professor at Tufts Center for the Study of Drug Development. He is also a Founder, Chairman/CEO of several ventures that serve clinical research and investor, board member and venture advisor. In our discussion we cover the reasons behind changes in protocol practice over the years. Discuss best practices in protocol development, understand why are protocols becoming so complex and what we do with all that data. We also dive into understanding what the regulators think about the volume of data we are collect, plus much more.
Craig Lipset joins Liam on this week’s podcast episode. Craig is Co-Chair of DTRA, Advisor, Founder of Clinical Innovation Partners and sits on a number of boards for companies in the Life Science space. Craig is really at the forefront of innovation and has launched a number of industry firsts such as the first fully remote/virtual clinical trial for a new medicine to the first returning of results and data to research participants. In our discussion we cover how and why DTRA was formed, what are the best use cases for decentralised trials, the biggest changes faced when running them and how to overcome them and much more.
The Endpoint Podcast: Episode 8 with Craig Lipset
Presented by Liam Eves
Michael Casey joins Liam on this week’s podcast episode. Michael is Executive Director at hyperCORE International and a highly sought-after magician! Michael has had the fortunate position to work across Pharma, CRO and at site, giving him a unique way of thinking! In this session, we chat about hyperCORE and Michael’s background, explore the differing viewpoints and insights of Pharma, CRO and site, talk about the disrupter mindset, understand how data helps decision making and we also get a little philosophical and meta!
Femida Gwadry-Sridhar joins Liam on this weeks podcast episode. Femida is the CEO and Founder of Pulse Infoframe. In this session we explore all things in the real world evidence space! What is it? How is it used? Where is it used? What lessons can we carry over to other therapy areas? And much more.
Karri Venn joins Liam on this weeks podcast episode. Karri is the President of Research at LMC Manna Research and the CEO of hyperCORE International. In this session we explore site operations, take a look at the impact decentralised trials have on sites and how to optimise for these changing times, and of course jump head first into site pain points and more importantly how to overcome them.
Earl Seltzer joins Liam on the podcast this episode. Earl is the Senior Director, Feasibility and Site Selection at Covance. In this session we dive into understanding what feasibility and site selection is, the process, challenges of global feasibility and understanding the pain points and how to overcome them.
Dr Peter Sargent joins Liam on the podcast this episode. Dr Sargent is currently Head of BD at NIHR but his Life Science experience covers scientific, operational and commercial. In this episode we find out what the NIHR is and how it supports Life Science organisations, we also explore what the UK is doing to speed up research alongside some other innovative research approaches.The Endpoint Podcast: Episode 3 with Dr Peter SargentPresented by Liam Eves
EPISODE 2: WITH DR PATRICK SHORTFounder and CEO, Sano Genetics
This week Liam is joined by Dr Patrick Short. Dr Short is the founder and CEO of Sano Genetics, a company who specialise in at home genetic screening and precision recruitment for companies developing precision therapies. In this session Patrick and Liam discuss at home genetic testing, the role of patient transparency and privacy in clinical trials, precision recruitment and much more.
This week Liam talks to Dr Andrew Catchpole about COVID-19, virology research and the world’s first SARS-COV-2 (COVID-19) human challenge model. Dr Catchpole is the Chief Scientific Officer at hVIVO, an industry leading services provider in viral challenge studies that supports product development for companies developing antiviral, vaccines and respiratory therapeutics.