In Search of Insight: Recent Episodes
Nootropics Depot
Nootropics Depot leads the supplement industry through expertly formulated products, tested in our world-class lab. Learn about the creativity behind Nootropics Depot's products, and the history behind the botanicals that keep us healthy and well in Nootropics Depot's monthly podcast.
NEW PRODUCTS! Caloriburn, Mitoburn, Kanna Powder, Mushroom Magic Latte & Coffee BALLER EDITION
https://nootropicsdepot.com/mushroom-magic-coffee-baller-latte/
https://nootropicsdepot.com/mushroom-magic-coffee-baller/
https://nootropicsdepot.com/fsk53-kanna-powder/
https://nootropicsdepot.com/caloriburn-capsules/
https://nootropicsdepot.com/mitoburn-capsules/
Chapters
0:00 Introduction
0:22 Mushroom Magic Coffee & Latte Baller
15:00 Kanna Powder
22:28 Caloriburn
32:51 Mitoburn
NEW PRODUCTS! InfiniLyte & BerbeLean
Learn about Nootropics Depot's new fitness supplements, InfiniLYTE and BerbeLEAN in this video! Our product specialist Emiel and In Search of Insight podcast host Erika break down the benefits, ingredients, and inspiration behind our two newest supplements.
NEW PRODUCTS! ReDaxin, DHEA, TauroMag, Magnesium Pidolate, Magnesium Glycerophosphate
Chapters
0:00 Introduction
1:42 TauroMag - Sleep Benefits, Relaxation, Mood
11:41 Magnesium Pidolate - Nootropic
14:00 Magnesium Glycerophosphate - Fitness
19:25 DHEA - Hormone precursor
24:26 ReDaxin - Recovery, oxidation and inflammation support
45:30 Recap
Mr. Happy | The Next Generation
Click the link to listen to our fascinating conversation with Joshua, or better know online as Mr. Happy. In this new episode you’ll learn about Joshua’s cutting edge immune system research, the importance of our microbiome in longevity, and modern approaches to lab testing, nootropics and supplements.
Tune into this month’s podcast and learn about
- Mr. Happy’s new research on the immune system and longevity
- How the gut and other microbiomes contribute to our physical and mental health
- Positive change in the nootropic supplement industry since the LongeCity days
- Why lab testing is essential for supplement users and producers
Podcast Chapters
1:27 Longecity Forum - Early Nootropics Community
3:20 Foundations of Supplement Experimentation
7:50 Shifting Towards Minerals and Micronutrients
15:30 Origins of Nootropics Depot + Our Purity Standards
18:31 Vendors and Sourcing
26:30 Lion’s Mane, Reishi, Mushroom Research
28:20 Cultivating Lion’s Mane
35:50 Reishi + Immune Response
39:40 Joshua’s Immune System Research - Biofilms
51:05 Future of Accessible Research Studies
55:00 Citizen Scientists
CistaMAX | The Road To The Perfect Cistanche
This month on the In Search of Insight podcast, Emiel and Erika share the inspiration behind Nootropics Depot’s new CistaMAX stack! We combined non-extracted Cistanche, a high-potency Cistanche extract, and a Supercritical Cistanche extract with Shilajit, Pregnenolone and DHEA to create CistaMAX. This combination produces a noticeable stimulating and motivating effect, and boosts the muscle-building properties of Cistanche.
In this podcast, you’ll learn why we chose each ingredient in CistaMAX and what purpose it serves in the stack as a whole. You’ll also learn about the neuroscience behind the focus and mood enhancing effect of Cistanche. There’s lots of reasons why we include CistaMAX in our daily stack - it can increase feelings of hunger, which is essential when bulking and building muscle. It also gives us a noticeable energy boost that makes us want to move more. CistaMAX is a great choice for supporting fitness, motivation, and hormonal balance. Listen to our new episode to learn more!
Buy CistaMAX from Nootropics Depot https://nootropicsdepot.com/cistamax-capsules/
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Podcast Chapters
00:00 Introduction
00:32 Exploring the elements of CistaMAX
3:46 What is the best dose for CistaMAX?
7:53 Hunger-boosting effects of CistaMAX
15:52 Steroidogenesis - androgenic benefits of CistaMAX
20:24 Gut-health benefits of Cistanche
26:51 Echinacoside and Acetoside - active compounds
32:14 Perceptible benefits of CistaMAX
32:40 CistaMAX and glucose absorption
40:22 Developing the CistaMAX stack
51:03 Pregnenolone, DHEA, and Shilajit in CistaMAX
55:29 Motivation, energy, and mood boost
1:01:51 How to determine what is and isn’t working in your stack
1:04:55 Does CistaMAX benefit workout recovery?
1:11:05 Conclusion
Tribugen | How We Took Tribulus To The Next Level
Tribulus Terrestris is a powerful supplement that boosts energy, motivation, and vitality! This month, Emiel and Erika discuss how Nootropics Depot took Tribulus Terrestris to the next level with Tribugen, our optimized stack that combines Tribulus with Mung Bean, Cordyceps, Dioscorea nipponica, and Fenugreek. Each ingredient in Tribugen was selected to compliment the stimulating and motivating effects of Tribulus, and in this episode Emiel discusses the mechanisms of action that are responsible for these effects.
Before Tribugen made it’s debut, the team at Nootropics Depot tried a variety of Tribulus Terrestris extracts to find the most motivating but smooth extract that would shine as a stand-alone product. When making Tribugen, we wanted to increase the motivation benefits of Tribulus, but to smooth out the stimulation and edginess of Tribulus when taken on its own. After a year of bioassaying Tribugen, adjusting the dosages of the synergistic ingredients, and sharing the pre-released stack with friends, family and colleagues, we arrived at the finished product. If you are interested in learning more about this process, and the ingredients that make up the Tribugen stack, tune into this podcast episode on your favorite streaming platform!
Podcast Chapters
0:00 Introduction
3:06 Mega-Dosing Tribugen
6:07 Making A Next-Level Tribulus Terrestris Extract
8:45 Why Do People Reach for Tribulus?
17:00 Where Do We Source Our Tribulus Terrestris?
18:40 β-carbolines - Monoamine Oxidase Inhibitors
21:00 Connecting Pharmacodynamics with Perceptible Benefits
24:00 Creating the Tribugen Stack
32:00 Taking Tribulus with Vignatex
34:00 How Cordyceps Interacts Within the Tribugen Stack
35:29 Cordyceps + Caffeine Connection
40:30 Choosing Synergistic Compounds + Dosages
58:30 Protodioscin + Diosgenin
1:05:19 DHEA
1:08:00 Focus Enhancing Effects of Tribugen
1:09:00 Stimulation Effects of Tribugen
1:21:00 Conclusion
March Mushroom Magic | Energy, Focus and Motivation From Your Daily Dose of Adaptogenic Mushrooms
Have you experienced the mood lifting, physically relaxing, cognition enhancing benefits of adaptogenic mushrooms? Listen to our new podcast episode as we review Nootropics Depot's new Mushroom Magic drink mixes! Emiel and Erika disucss how Nootropics Depot sources coffee, matcha and cocoa for the most delicious drinking experience, and why Mushroom Magic drinks are great to share with friends and family! Learn more about why we chose Lions Mane, Cordyceps, Tiger Milk and Poria mushroom for our blend of gut health boosting, energizing, and immune supporting drink mixes.
Learn More About Lions Mane and Tiger Milk Mushrooms
Lion’s Mane Mushroom | The Journey To Connect Modern Science With Traditional Chinese Medicine
Tiger Milk | Could It Be The New Lion's Mane? | This Rare Malaysian Mushroom Is Finally On The Prowl
Follow Us on Instagram
Podcast Chapters
00:00 Introduction
00:40 Introducing Mushroom Magic Drink Mixes
1:02 Gut Function and Microbiome
1:45 Beta Glucans and Polysaccharides Benefit Our Gut
3:45 Follow Us On Instagram @insearchofinsight
5:20 Poria Mushroom Sclerotium
6:25 Check Out Emiel’s Updated Stack on Reddit
8:15 Unextracted Mushrooms Contain More Beta Glucans
9:00 500 Milligrams of Poria, Lion’s Mane, Cordyceps, and 150 mg Tiger Milk
11:20 Why Mushroom Magic Drinks Contain SCOOPS
19:35 Drinking Mushroom Magic Matcha - iced latte with milk
25:20 Stevia - Why We Sourced a Higher Quality Stevia
28:00 Perceptible Effects of Mushroom Magic Matcha
31:50 Our Matcha vs. Traditional Matcha Teas
34:50 Ceremonial Grade Matcha
38:05 Effects of Poria and Tiger Milk sclerotium
49:25 Checking in On the Perceptible Benefits
56:39 The Difference Between Caffeine and Mushrooms in Isolation vs. Mushroom Magic mixes
58:05 Beta Testing Mushroom Magic drinks with friends, family and coworkers
1:07:30 Drinking Mushroom Magic Coffee
1:20:43 Non-Perceptible Benefits of Adaptogenic Mushrooms
1:26:29 Drinking Mushroom Magic Cocoa
1:39:38 Cordyceps Mushroom Health Benefits
2:08:30 Drinking Mushroom Magic Coffee Latte
2:12:40 Mushroom Magic with your Daily Supplement Stack
2:14:20 Be Moderate When Taking Multiple Doses of PreBiotics - Digestion
2:19:00 Coffee Approved By Coffee Nerds (Emiel and Erika)
2:20:30 Closing Remarks on Perceptible Benefits of Mushroom Magic Drinks
Your Body’s Amazing Immune System | Is It Better To Take A Natural Approach When You Get Sick?
Our immune system is our body’s defense against sickness and infection. In this month’s podcast episode, Emiel and Erika discuss inflammation, oxidation, immune supporting supplements, fermented foods, and gut health, and explore ways to stay healthy all year round.
This episode is focused on why inflammation and oxidation are essential for helping us fight off pathogens, and therefore, why taking a natural approach when getting sick may help us recover faster. Sometimes, it can be advantageous to lean into the inflammation and oxidation caused by our immune system, though this can be uncomfortable. Dampening inflammation and oxidation can prolong illness, and work against our immune system’s natural response to pathogens.
Tune into the new podcast episode to learn more about:
- How inflammation and oxidation are tools that the immune system uses to attack pathogens and help us recover from illness
- Why fermented foods and carbohydrates are essential for a healthy immune system
- Vitamins, minerals, and supplements that support a healthy immune system
- The connection between the gut and the immune system
- Why symptom management during illness can work against us, and what to do instead
Podcast Chapters
00:00 Introduction - Immune System
01:15 How Does Our Environment Affect Our Immune System?
05:30 Inflammation and Oxidation are Tools of the Immune System
06:45 Taking GABA for Immune Function
17:20 The Impact of Gut Health on the Immune System - Why Kombucha?
18:50 How Lindsay Lohan Ruined The Kombucha Industry
23:40 Stomach Acid is the First Line of Defence Against Viruses and Bacteria
26:44 How Fermentation and Food Preservation Supports Our Immune Function
30:44 Sauerkraut - Low PH Means Bad Bacteria Die, Good Bacteria Live
36:25 Short Chain Fatty Acids - Fibers, prebiotics, and biotics
42:45 How the Immune System Functions Beyond Our Gut
46:05 We Have Microbiomes Everywhere
47:55 Innate vs. Adaptive Immune System
57:30 How Genetics Factor Into Our Immune System Response
1:00:00 Leaning Into the Immune Response
1:09:43 Why Do We Get Fevers When We Get Sick?
1:30:16 Sickness Behavior
1:34:34 How To Boost Immune System When You’re Not Sick
1:54:00 Behavior, Micronutrients, and Mushrooms
2:14:00 How to Take Supplements When Getting Sick
2:18:47 Supplements to Support Your Immune System
2:33:39 GABA for the Gut, Mood, and Immune System
2:36:14 Conclusion
Kanna | Can This South African Succulent Make You a Better Dancer?
Kanna is a unique succulent plant, originating from South Africa. It has been used as a mood and energy boosting botanical for thousands of years by the KhoiSan people of South Africa, for dancing ceremonies and as a hunting aid.
In this month's podcast episode, Emiel (Nootropics Depot Product Specialist) and Erika discuss the history of Kanna, its pharmacokinetics and mechanisms of action, and how Kanna provides a distinctly uplifting effect from its serotonergic activity.
Tune in to learn about dosing Kanna, taking Kanna at night clubs in Amsterdam, mesembrine, mesembrenone, and Delta 7 mesembrenone, and why you should try Kanna for its pro-social benefits.
Follow In Search of Insight on Instagram https://www.instagram.com/insearchofinsight?igsh=ZGNjOWZkYTE3MQ%3D%3D&utm_source=qr
Buy Full Spectrum Kanna Tablets from Nootropics Depot https://nootropicsdepot.com/full-spectrum-kanna-extract-quick-dissolve-tablets/
Read Nootropics Depot's Blog on Kanna https://nootropicsdepot.com/kanna-lift-mood-and-lower-stress
Podcast Chapters
00:00 Introduction
04:10 Dosing Kanna
09:40 Stimulating Effects of Kanna
11:50 Fat or Water Soluble? Bioavailbility of Kanna
17:30 Oral & Sublingual Administration
18:53 Pharmacokinetics - T Max and C Max
34:00 Caffeine Usage and Concentration
36:00 Dynamax Pharmicokinetics
38:45 Mood, Focus, Energizing, Pro-Social Effects of Kanna
43:00 Traditional Uses of Kanna, Amanita Muscaria, Kava
50:00 Neuroscience of Kanna - Neurotransmitter Releaser
53:07 Mesembrine acts as a VMAT2 Upregulator
1:03:40 Testing Mesembrine Content of Kanna Extracts
1:14:10 Cultivars of Kanna - Sceletium tortuosum
1:14:54 What Sets Nootropics Depot’s Kanna Extract Apart
1:18:22 Beta Testing and Initial Bio-assaying
1:25:31 Kanna as a Subtle Appetite Suppresant
1:33:11 Emiel & Erika’s Current Occasional Supplements
1:47:07 Emiel & Erika’s Daily Supplement Stack
1:57:24 Conclusion
Isoliquiritigenin | Candy For Your Brain
This month, learn all about neurotransmitters and the powerful mechanisms of action behind Nootropics Depot’s mood-boosting licorice root extract, Isoliquiritigenin. Erika and Emiel take you on a journey through the traditional uses of licorice, what makes it such a soothing remedy for inflammation, and where licorice candy originates from.
Buy Isoliquiritigenin from Nootropics Depot https://nootropicsdepot.com/isoliquiritigenin-controlled-dissolve-tablets/
Follow In Search of Insight on Instagram
https://instagram.com/insearchofinsight?igshid=MzMyNGUyNmU2YQ%3D%3D&utm_source=qr
Podcast Chapters
00:00 Introduction
00:18 Licorice Root
03:53 Isoliquiritigenin
06:07 Mega-Dosing Isoliquiritigenin
10:27 Traditional Uses of Licorice Root
14:23 Why Is Licorice Candy Black?
15:28 Where The Classic Licorice Flavor Came From
24:32 Slight Detour - The Use of Quinine in Tonic Water
28:58 The Medicinal Background of Vermouth, Absinthe, Coca Cola
32:00 Tasting Dutch Licorice
35:12 Ammonium Chloride as a Cough and Mucus Remedy
43:00 Laws Against Licorice
44:54 Tasting Mild Salt Licorice
48:02 Benefits of Licorice Root and Isoliquiritigenin
54:12 The Pharmacology of Isoliquiritigenin
57:36 Neurotransmitter Basics
1:00:38 What Effects are Produced When Norepinephrine, Serotonin, and Dopamine Build Up?
1:02:34 GABA-A and GABA-B Activation
1:06:20 GABA, Amino Acid Neurotransmitter vs. Norepinephrine, Serotonin, and Dopamine Monoamine Neurotransmitter
1:08:19 Why We Typically Try to Dampen Glutamatergic Activity
1:09:40 Glycine, a Neurotransmitter
1:16:17 Dopamine D3 Agonist Effects of Isoliquiritigenin
1:18:38 Isoliquiritigenin For Pain Management
1:20:21 Isoliquiritigenin For Long Term Potentiation
1:22:47 Tonic Water - Traditional and Modern Uses
1:26:32 New Products From Nootropics Depot - Mushroom Magic Matcha
1:31:57 Why Not Ceremonial Grade Matcha?
1:36:55 The Mushroom Blend of Mushroom Magic Matcha
1:46:08 The First Scoop for Nootropics Depot
1:48:48 Full Spectrum Kanna Tablets
1:55:21 Taking Kanna at the Club
1:57:27 Conclusion
An Unexpected Journey Through The Past & Future Of Supplements With Lucas Of Boost Your Biology
This month on In Search of Insight, we welcome Lucas Aoun from Boost Your Biology and embark on an unexpected, stimulating journey through the past and future of supplements.
Learn More About Lucas Aoun of Boost Your Biology https://www.youtube.com/@UC4O8s5Eir3A0ULQ-0HOJr8Q https://www.youtube.com/@UCG-Da6bw7vNJ4oEkhs-D_KQ
Meet Lucas and learn about his background as a biohacker, Naturopath, and supplement enthusiast. In this episode, Emiel, Lucas, and Erika share the beginnings of their journeys with supplements. They discuss what products they’ve loved and hated, new frontiers in the supplement world, and why quality and safety are the most essential elements in supplementation.
Podcast Chapters
0:00 Introduction
1:15 Beta Testing Unreleased Cistanche Stack + Tribugen
5:00 Meet Lucas Aoun
6:45 Extraction Technique for Cognance - Producing a Non-Drowsy Bacopa Extract 14:00 Glycosides in Botanicals
17:21 Extraction Techniques of Cognance, Erinamax
21:47 Lucas’ Journey in Nootropics Begins
23:28 Acetyl L-Carnitine, an Early Adopted Nootropic
26:33 Emiel’s Journey in Nootropics Begins
28:41 Bioassaying Tribugen
31:59 Pre-Workout Formulations
34:15 Ginkgo Biloba
38:31 Clinical Trials vs. Empirical Evidence
39:49 Approaches to Research
42:18 Asking Questions, Asking the Right Questions
46:18 How Reddit Inspired Nootropics Depot 49:08 Benefits of Community Bioassaying
51:41 Staying Close to the Source When Researching
56:19 When Research Studies Can’t be Verified
59:02 The Origins of Acetylcholinesterase inhibitors
1:01:25 Plant Defence Systems
1:04:38 Beta Ecdysterone
1:06:39 Being Critical of Research
1:09:34 Erika’s Journey with Nootropics Begins
1:14:34 Safety Concerns of Fadogia Agrestis
1:17:21 Fadogia Agrestis Toxicology
1:20:45 The Future of Nootropic Supplements from Africa
1:21:20 Kanna and its Traditional Uses
1:38:00 Naturopathy and Nootropics
1:40:00 Criteria for Nootropics - Gurgia
1:47:40 How Traditional Chinese Medicine Informs Modern Nootropics
1:51:00 Shizandra Chinensis
1:52:20 Eria Jarensis
1:54:40 Dynamine
2:02:16 The Benefits of Progesterone
2:08:25 Enhancing Insulin Sensitivity
2:09:20 Conclusion
Megadosing And DNA Testing w/ Joe Cohen | Why The Founder Of SelfDecode Takes 150 Supplements A Day
This month we welcome our featured guest, Joe Cohen of SelfDecode to the In Search of Insight Podcast. Joe’s passion for quality supplements, enthusiasm for sharing his knowledge, and commitment to lab testing is unmatched in the industry. Learn about SelfDecode, the ways that genetic testing and supplement testing work together, and how Joe Cohen tests new supplements with mega dosing. Tune into this month’s podcast episode to learn about:
- Why Joe Cohen takes 150+ supplements every day
- What sets SelfDecode apart from other supplement recommendation tools
- Megadosing Nootropics Depot supplements
- How Joe boosts his testosterone, supports thyroid function, and monitors health risks through supplementation and frequent blood tests
- Joe’s favorite Nootropics Depot supplements
Joe's 150+ Supplement Regimen
My Regimen of 150 Supplements
https://selfhack.com/blog/joes-personal-health-regimen/
My Regimen of 150 Supplements (Detailed)
https://selfhack.com/blog/my-regimen-of-150-supplements-why-i-take-them/
Podcast Chapters
0:00 Introduction
2:22 Why Joe Cohen Mega Doses Supplements
10:00 Megadosing Cognance
18:37 Supplements with Anti-Thyroid function
22:56 Introducing SelfDecode
31:17 Biggest Mistakes in Genetic Testing
39:52 Optimizing Your Biology
43:36 Joe Cohen’s 150+ Supplement Stack
45:49 Mood, Cardiovascular Health, Kidney Health, Thyroid Function
54:44 The Benefits of Frequent Lab Testing
58:46 Why Supplement Lab Tests and Blood Lab Tests Are Important
1:03:48 Breaking Down Joe’s Supplement Stack
1:08:14 Supplements to Support Food Tolerance
1:12:26 The Difference Between SelfDecode and Other Supplement Advice Tools
1:20:49 Checking In on the Cognance Megadose
1:21:19 How Bacosides Effect Thyroid Hormone
1:26:22 Necessity for Data in Supplementation
1:29:24 Joe’s Testosterone Benefits from Tongkat Ali
1:35:29 Clinical Trials for Supplements
1:38:20 Joe’s Favorite Nootropics Depot Supplements
1:38:20 Megadosing Sabroxy
1:50:19 The Human Element of Supplementation
1:56:45 Lab Testing and Safety of Supplements
2:02:31 Joe’s Favorite ND Supplements, Continued
2:23:51 Conclusion
Discovering Bacopa | What’s Hiding In Plain Sight?
If you’re a part of the Nootropic supplement world, you know that Bacopa is a powerful and effective supplement for memory, sleep quality, relaxation, and mood. However, there are many fascinating mechanisms at play that have made Bacopa a well-known supplement for centuries, even in traditional Ayurvedic practices. Bacopa is more than just a supplement, commonly used as a decorative plant, growing in semi-aquatic environments in the wild, and can be found for sale in nurseries around the world. It’s time to discover the wonders of Bacopa, the Nootropic botanical that is hiding in plain sight!
Chapters
0:00 Introduction
2:50 Dosing Bacopa 24%
3:13 Our New Microphones
6:51 Line Audio CM4 Microphones
12:08 Positive vs. Negative Responses to Bacopa
13:29 Benefits of Cognance vs. Traditional Bacopa extract
16:44 Mushroom Kingdom Update
18:06 Hericium Coralloides, Hericium Abietis, Hericium Americanum, Hericium Erinaceus
19:28 The Difference Between a Cultivar and a Species
21:53 Comparing Coffee, Hemp, and Hops Cultivars
24:13 Investigating Cultivars and Species in Mushroom Kingdom
27:46 Evaluating the bioactive differences between Cultivars and Species
30:11 High Performance Thin Layer Chromatography
32:18 Image of HPTLC Plate
39:26 Mushroom Cultivation Logistics
41:35 Why We Source Mushrooms from Asia
44:02 Perceptible Effects of Bacopa 24%
52:29 Stacking Bacopa 24% with Cyanidin 3-Glucoside
54:45 Dosing Bacopa at Nighttime vs. Daytime
55:22 Why Bacopa enhances sleep quality
57:21 The Cyanidin 3-Glucoside Shortage
1:00:25 The Difference Between Synapsa, Bacognize, Bacopa 24% and Cognance
1:04:17 Bioavailability - Taking with or without a fat source
1:05:03 Bacopa is More Common Than You Think
1:07:03 Why We Adhere to Prop - 65 Heavy Metal Limits
1:07:58 From Ayurvedic Bacopa to Modern Extracts
1:11:13 Why Saponins Make Standardizing Bacopa a Challenge
1:13:20 Bacoside A
1:15:00 HPTLC Testing vs. UVVis
1:17:04 Standardization of Synapsa, Bacognize, Bacopa 24%
1:25:07 Cognance Effects vs. Traditional Bacopa Extracts and Ebelin Lactone
1:35:17 Beta-testing Cognance
1:43:55 Comparing Bacopa Extract Effects to Wine
1:47:02 Stacking Bacopa 24% with Cyanidin 3-Glucoside
1:51:42 Norepinephrine Balancing Effect of Bacopa
1:52:13 Serotonin Modulating Effect of Bacopa
1:55:23 Enhances Density of the 5-HT3A Receptor
1:56:41 Tryptophan Hydroxylase and Increasing Density of Serotonin Transporter
1:58:07 Combining Full Spectrum and Targeted Standardized Extracts
2:00:08 Bacopa as an Adaptogen
2:01:10 Bacopa and GABA
2:04:38 How Long Does it Take for Bacopa Effects to Kick In?
2:06:19 Memory Benefits of Bacopa Extracts
2:16:13 Stacking with Bacopa 24%
2:17:21 Focus, Mood and Memory Stack - Bacopa 24%, Cognance, Saffron, Sabroxy
2:20:49 Relaxation Stack - Bacopa 24%, Shoden Ashwagandha, Tetrahydromagnolol, GABA
2:22:38 Lights Out Stack - Bacopa 24%, Supercritical Coriander, Oleamide, Magnolia Bark, Tetrahydromagnolol
2:23:02 Memory Stack - Mr. Happy Stack - Bacopa 24%, OmegaTau
2:24:19 Nootropic Memory Enhancement - Bacopa 24%, OmegaTau, Cognance, Erinamax
2:25:54 Conclusion
Lion’s Mane Mushroom | The Journey To Connect Modern Science With Traditional Chinese Medicine
Learn what sets Nootropics Depot’s Lion’s Mane Mycelium apart from the crowd in episode #22 of the In Search of Insight podcast.
This month we discuss our new Lion’s Mane mycelium product and the years of research and testing we spent creating this next-level supplement. Tune into the podcast to learn about Lion’s Mane mycelium, and listen to Erika, Emiel and Jay discuss:
- The difference between fruiting body and mycelium supplements
- How Lion’s Mane mycelium benefits cognitive health, nerve health, and mood
- Perceptible effects of our new Lion’s Mane Mycelium
- How Omnient Labs is raising the bar for standardization in the supplement industry
Buy Lion's Mane Mycelium from Nootropics Depot
https://nootropicsdepot.com/erinamax-tablets/
Buy Isoliquiritigenin from Nootropics Depot
https://nootropicsdepot.com/isoliquiritigenin-controlled-dissolve-tablets/
Podcast Chapters
0:7 Introduction
1:30 Taking Lion’s Mane Mycelium
12:01 New Product Release - Isoliquiritigenin
16:22 Sublingual Dosing
22:08 Isoliquiritigenin Video
23:50 Health Benefits of Isoliquiritigenin
30:55 Dopamine Reuptake Inhibition
39:25 Why Try Isoliquiritigenin
44:58 Noticeable Effects of Lion’s Many Mycelium
50:20 Nerve Benefits from Mycelium
53:34 Standardizing Lion’s Mane to Erinacine A
57:10 NGF + TrkA Receptor Stimulation
1:05:40 Review of Lion’s Mane Mycelium Benefits
1:12:00 Special Guest James Jursich
1:14:05 Initial Stages of Lion’s Mane Mycelium Research
1:18:41 Building Growth and Testing Methods
1:25:04 From Mycelium to Liquid Culture
1:26:51 Producing Liquid Culture at Commercial Scale
1:34:43 NMR - MRI for Molecules
1:40:39 Why Did Nootropics Depot Create a Mycelium Product?
1:46:53 Benefits of Lion’s Mane Mycelium vs. Fruiting Body
1:48:02 Developing Mushroom and Mycelium Research
1:56:49 The Risks of Contamination in Materials
2:04:43 Research for Practical Use of Mycelium
2:06:44 Jay’s New Video Series
2:10:29 Comparing Nootropics Depot’s Mycelium to Mycelium-On-Grain
2:07:30 Stacks
2:15:26 Four Mushroom Blend
2:18:52 Inflammation Support Stack
2:20:36 Inspiration Stack
2:24:44 Microdose Stack
2:25:58 Final Check-In for Perceptible Effects of Mycelium
2:30:37 Conclusion
Cyanidin 3-Glucoside | Stimulator Of The Body & Mind | Muscle Growth, Mood, Recovery, & Cognition
This month, tune into In Search of Insight to learn about Cyanidin 3-Glucoside - a potent anthocyanin that can be found in Black Rice, famous for its benefits for fitness, mood, and cognitive health. This podcast explores our new Cyanidin 3-Glucoside extract and how it can be specifically useful for bodybuilders, athletes, or anyone looking to optimize their nutrition and build muscle. Your podcast hosts Emiel and Erika also discuss the perceptible mood effects of the extract, its cognition benefits, and stack ideas to try with Cyanidin 3-Glucoside.
Buy Cyanidin 3-Glucoside from Nootropics Depot
https://nootropicsdepot.com/cyanidin-3-glucoside-capsules/
Podcast Chapters
0:00 Introduction
0:36 Taking Cyanidin 3 Glucoside
6:00 Dosing Cyanidin 3 Glucoside
6:55 New Product Releases
7:19 L Citrulline
9:30 The Difference Between L Citrulline & L Arginine
13:50 Nitric Oxide for “The Pump”
16:55 Stacking L Citrulline with Lemon Balm, Maca
17:35 Siberian Euluthero
21:00 Cyanidin 3 Glucoside
23:30 Glucoside of Cyanidin
27:00 Cyanidin is a Monoamine Oxidase Inhibitor
30:54 Combining Caffeine with Cyanidin 3 Glucoside
32:00 Identifying Anthocyanin-Rich foods
39:15 Cognition Benefits of Cyanidin 3 Glucoside
40:05 BDNF
60:00 Nutrient Partitioning
68:27 Recovery Benefits
90:00 Red Wine Stack
95:00 Recovery Stack
100:20 Cognition & Mood Enhancing Stack
Fenugreek | From Mummies to Modern Supplements | The Return of an Ancient Mood Booster
Fenugreek boosts mood, enhances motivation and supports your workout recovery. If we were giving superlatives, Fenugreek would certainly win the “team player” award! Many of us are likely familiar with this botanical, due to its incorporation into various foods, most notably curries, and imitation maple syrup. Fenugreek is also famously used for its fitness-boosting effects, with some claiming it enhances testosterone levels. Yet, the nootropic and mood-boosting effects of fenugreek remain relatively unexplored, although murmurs of these effects are sprinkled all over the web.
On this episode we dig deeper into these unique mood, cognition and fitness-enhancing effects, finally getting to the root of what this wonderful botanical is capable of! A big focus of this episode is on the bioactive compounds in fenugreek, specifically, trigonelline and protodioscin, two of the compounds we have standardized our fenugreek extract for. Trigonelline is a compound that is found in relatively high amounts in coffee, and appears to contribute to both the stimulating and mood-boosting effects of this invigorating elixir! It’s a compound we became intimately familiar with during our research for our take on a highly efficacious caffeine stack, which ended up materializing as DynaMAX. Although trigonelline never made it into DynaMAX, it’s a compound we kept in the back of our minds, waiting for a chance to explore it further. Turns out, fenugreek was that chance! Combining the dopamine-releasing properties of trigonelline, with the motivation, and confidence-enhancing properties of protodioscin, resulted in a really unique effects profile. Imagine Tribulus, but tuned down in terms of aggressive energy, and tuned up in terms of mood-brightening properties. Quite the winning combination in our books!
This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
- Our new fenugreek extract and its standardized compounds, protodioscin and trigonelline
- How fenugreek boosts focus and motivation
- Why trigonelline is an important compound for mood in both fenugreek and coffee
- Creating the ideal pre-workout and post-workout stack
- The mechanisms for fenugreek’s metabolic health benefits
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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Everyday Essentials | Magnesium Glycinate, L-threonate, Sucrosomial, ClariMAG | Which Form Is Best?
Magnesium is an everyday essential mineral that our body uses in thousands of daily functions. In this month's podcast, Emiel and Erika discuss how to find the best form for your needs, and why Magnesium is so important in maintaining healthy muscles, digestive function, cognition and memory. Tune into the conversation and learn about:
- Why Magnesium is an essential addition to your daily supplement stack
- Magnesium’s cognitive, muscular, digestive, and sleep benefits
- Magnesium in our diet and everyday lives
- Which form of Magnesium is best
- Choosing the right Magnesium supplement for your needs
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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Magnesium Glycinate
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Magtein - Magnesium L-threonate
https://nootropicsdepot.com/magtein-magnesium-l-threonate-capsules/https://nootropicsdepot.com/magnesium-l-threonate-powder/
MicroMag - Sucrosomial Magnesium
https://nootropicsdepot.com/micromag-capsules-optimized-magnesium/https://nootropicsdepot.com/micromag-powder-optimized-magnesium/
ClariMAG
https://nootropicsdepot.com/clarimag-capsules/
New Products from Nootropics Depot
Infini-B Optimized B Complex Capsules
https://nootropicsdepot.com/infini-b-capsules/
GABA Capsules
https://nootropicsdepot.com/gaba-capsules/
Cycloastragenol Capsules
https://nootropicsdepot.com/cycloastragenol-10-capsules/
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Sabroxy | Oroxylum indicum Bark | Is Oroxylin-A Really as Good Of A Dopamine Booster As They Say?
In Search Of Insight Episode #017 - Sabroxy
How do we enhance dopamine levels for better mood, focus, and motivation? This month on the In Search of Insight podcast, learn about Oroxylin-A and the mechanisms of action that make it a powerful dopamine reuptake inhibitor in Sabroxy.
This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
- Sabroxy, the Oroxylum Indicum tree, and Oroxylin-A
- How Oroxylin-A works as a Dopamine Reuptake Inhibitor
- The Nootropic effects of Sabroxy
- Traditional uses versus modern uses of Oroxylum Indicum
- Stack combinations with Sabroxy
- Emiel and Erika’s daily supplement stacks
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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Pregnenolone | The Master Hormone Precursor | A Perfect Ally For Testosterone Boosting Supplements
In Search Of Insight Episode #016 - Pregnenolone
Supplementing Pregnenolone in low doses can help us balance our hormonal profiles, build muscles, and maintain a positive mood. Gain a deeper understanding of our body’s hormone production process, and how Pregnenolone works as the master hormonal precursor. This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
- Pregnenolone, the master precursor to our body’s steroid hormones
- How pregnenolone transforms into testosterone, estrogen, and corticosteroids
- Why less is more when dosing Pregnenolone for daily supplementation
- Pregnenolone stack combinations to optimize hormonal balance
- New products from Nootropics Depot
Buy Nootropics Depot Pregnenolone Tablets
https://nootropicsdepot.com/pregnenolone-quick-dissolve-tablets/
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Supercritical Coriander | Exploring The Novel Effects Of The Potent Seeds Grown By Ukrainian Farmers
Coriander has been used as a prized culinary ingredient in many cultures for centuries. So what health benefits does it offer when concentrated for its most powerful compound, Linalool?
Tune into this month’s podcast episode to learn about Coriander’s history of use, and how our Supercritical CO2 extract benefits sleep, mood, relaxation, and digestive health. This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
Supercritical CO2 Coriander extract, and its main active compound, Linalool
The mood, relaxation, sleep, and stress benefits of Coriander
Why Coriander, Hops, and Lavender have been used as food sources for centuries
How Linalool acts on the GABAergic system
Why Supercritical CO2 is the ideal solvent for botanical extracts
Supplement stacks to explore with Supercritical Coriander
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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Cognance - Bacopa Reimagined | The Quest For Ebelin Lactone And A Natural Microdose Alternative
What does it take to create a natural microdose alternative?
Tune in to episode #14 of In Search of Insight to learn about the process of creating Cognance, our reimagined Bacopa supplement. In this new episode, your hosts Emiel and Erika discuss:
The mood, memory, confidence, focus, and cognitive benefits of Cognance
Why Ebelin Lactone is the key compound in Cognance
The product creation process from start to finish
Supplement stacks to maximize the benefits of Cognance
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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What’s the hype behind Red Reishi mushroom?
In this month’s podcast episode, we discuss the mushroom growth process, the many health benefits of Red Reishi, and how Nootropics Depot created the most potent Red Reishi extract on the market! This month, your hosts Emiel and Erika dive into an exciting conversation about:
Red Reishi cultivation, processing, and origins
How Ganoderic Acid benefits mood, sleep, respiratory health, and cardiovascular health
The difference between mycelium versus fruiting body mushroom extracts
Supplement stacks to maximize the benefits of Red Reishi
Nootropics Depot’s latest product releases
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
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What makes Saffron the world's most expensive spice, and why have humans been using it for thousands of years? In this month's podcast episode, we discuss Saffron's careful cultivation and processing, as well as its many mood-boosting and health-promoting properties. This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
-Saffron cultivation, processing, and origins
-Saffron’s benefits for mood, cardiovascular health, sleep, and vision
-Why Saffron is the world’s most expensive spice
-The best products to stack with Saffron
-Nootropics Depot’s latest product releases
Listen to Episode #012 of In Search of Insight now, all about Saffron! Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
Maca has become famous globally for its mood, vitality, and energy benefits. In this month’s podcast episode, we explore the origins of Maca, its traditional uses as a food source and supplement, and the mechanisms of action for its many health benefits. This month, your hosts Emiel and Erika dive into an exciting conversation and discuss:
-Maca’s origins, traditional uses, and ancient history
-Maca’s mood, energy and vitality boosting mechanisms
-How Maca balances hormonal profiles
-Why proper processing is essential to Maca’s benefits
-Nootropics Depot’s latest product releases
Click the link below to listen to Episode #011 of In Search of Insight now, all about Maca! Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
Pain is a universal human experience, but understanding it can be quite complex. What are the different kinds of pain that we sense, and how does our mental state affect how we perceive pain? Learn about pain pathways, pain as a protective mechanism, and supplements that can help us manage pain acutely and long-term. The better we understand where pain comes from, the more equipped we are to manage pain and understand how our bodies sense the world around us. This month on the In Search of Insight Podcast, your hosts Emiel and Erika dive into an exciting conversation and discuss:
-Pain Pathways and Triggers
-Nociceptive Signals and Inflammatory Soup
-How Our Mental State Influences our Perception of Pain
-Pain as a Protective Mechanism
-Supplements that can Help Manage Pain
Click the link below to listen to Episode #10 of In Search of Insight now, all about Pain! Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
NAD+ is an endogenous compound that is responsible for cell activity, brain health, fertility, aging, and many more essential functions in our bodies. So how do we maintain healthy levels of NAD+ as we age, and what are the best strategies for keeping energy levels, mood, and cognition in tip-top shape for the long haul? This month on the In Search of Insight podcast, your hosts Emiel and Erika break down what NAD+ is, its biosynthesis pathways, and how supplementation can support healthy NAD+ levels as we age. This month on episode #009, dive into an exciting conversation and learn about:
-The biosynthesis pathways for NAD+
-How NMN and NR work together for optimal NAD+ support
-The synergism between Sirtuins and NAD+
-Why fasting is crucial for maintaining NAD+ levels
-Who can benefit from supplementing NAD+ precursors
-Fertility, cognition, metabolism, and strength benefits from NAD+
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
If you’ve ever searched for libido-enhancing supplements, you’ve certainly heard of Horny Goat Weed. While you might be familiar with Horny Goat Weed’s libido benefits already, you may be surprised by its powerful effects on mood, sleep, and anti-aging! This month on episode #008 of In Search of Insight, learn about Horny Goat Weed’s benefits, mechanisms, and long history of use with your hosts u/Pretty-Chill and u/NootropicsDepotGuru. In this podcast, we discuss:
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Horny Goat Weed’s Libido-Boosting Mechanisms
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The Surprising Cognitive Benefits of Horny Goat Weed
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Why Estrogen Is Important For Men & Women
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Why Horny Goat Weed Promotes Better Sleep
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Nootropics Depot's Latest Product Releases
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Podcast Listener Questions from Reddit
Be sure to subscribe to the In Search of Insight podcast on your favorite streaming platforms, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
Hormones are responsible for nearly every function in our bodies. So should men and women treat supplements differently based on our hormonal profiles?
In episode #007 of In Search of Insight, your hosts Emiel and Erika dig into this question and explore how body composition, hormonal cycles, and aging affects supplementation in men and women. Listen now to learn about the nitty-gritty mechanisms of female hormone cycles in menstruation and menopause, the role of estrogen and testosterone in men and women, and why men and women’s supplement needs become more similar as we age. In this podcast, we discuss:
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Hormonal Cycles in Women vs. Men
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Synergizing Supplements With Your Menstrual Cycle
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Why Men And Women Become More Similar As We Age
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Nootropics Depot's Latest Product Releases
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Podcast Listener Questions from Reddit
Be sure to share In Search of Insight, and join a community of like-minded nootropics geeks just like you on Reddit at r/NootropicsDepot.
Tune into a brand new episode of In Search of Insight podcast, all about testosterone supplementation! Maintaining healthy testosterone levels is essential for boosting drive, building muscle, and staying motivated to tackle daily challenges. Learn about the myths of testosterone supplementation, why Tongkat Ali and Cistanche are so effective, and why you should think twice before ordering yourself a bottle of Fadogia Agrestis.
This month, your hosts Emiel and Erika dive into an exciting conversation and discuss
- The Best Testosterone Supplements On The Market
- How To Boost Drive, Build Muscle, and Stay Motivated
- Common Myths About Testosterone Supplementation
- Testosterone for Men AND Women
- Your Testosterone Questions from Reddit
A Delicate Balance | The Science Behind Intelligent Supplement Stack Development | *Natrium Health*
This month, your hosts Erika u/NootropicsDepotGuru and Emiel u/Pretty-Chill dive into an exciting conversation about Nootropics Depot’s most complex task: creating effective and synergistic supplement stacks!
Learn about the origins of Nootropics Depot’s sister brand Natrium Health, and the stack development process that goes into each Natrium product. Each month, Erika and Emiel answer listener questions from our Reddit Q&A thread on r/NootropicsDepot. Tune in to see if your question was featured in this month's podcast episode!
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A new episode of In Search of Insight is now available to listen on your favorite streaming platforms! This month, your hosts Erika u/NootropicsDepotGuru and Emiel u/Pretty-Chill dig into the synthesis, pathways, and effects of Glutathione in the body, and why you should consider enhancing your glutathione levels with a variety of essential supplements.
Each month, your hosts answer listener questions from our subreddit, r/NootropicsDepot. Tune in to see if your question was featured in this month's podcast episode. This month, you'll also hear a brand new segment for In Search of Insight; New Product Releases!
Listen to In Search of Insight episode #004 now - Is Glutathione Really A Master Antioxidant? Immunologists Claim its the Most Underrated of Them All!
Will You Use These Supplements to Optimize Your Physical and Mental Health in 2022? | MINDFULNESS
Your hosts Erika u/NootropicsDepotGuru and Emiel u/Pretty-Chill take an introspective approach to this month’s episode of the In Search of Insight podcast. While most people know that supplements can optimize our physical and mental health, much fewer people know how to determine what’s working and what’s not when it comes to supplements. We’re looking forward to sharing this podcast episode with you, which features listener and Redditor questions about bio-assaying, mindfulness, and how to optimize your physical and mental health with supplements in 2022.
In Search of Insight by Nootropics Depot
Episode #002 | Is Andrographis the Best Ancient Herb for Respiratory and Immune Health? Is Thailand Onto Something?
We’re back with another episode of In Search of Insight, discussing the vast and fascinating benefits of Andrographis Paniculata. Learn about the novel pathways through which andrographis supports respiratory function, balances inflammation, supports a healthy sleep cycle, and more in episode #002 of In Search of Insight.
For this episode of In Search of Insight, your hosts Emiel and Erika answer questions from our listeners and Redditors about andrographis’ affect on sexual function, synergistic botanicals, the most surprising aspects of andrographis, the mechanisms that make andrographis a great sleep supplement, and why andrographis seems stimulating, but actually isn’t. With your help and participation, we’ve uncovered groundbreaking research to share with you about andrographis paniculata in this episode of In Search of Insight!
In Search of Insight by Nootropics Depot
Episode #001 | Can You Really Improve Exercise Recovery with a Simple Berry? Tart Cherry is a Workout Gamechanger!
Meet your hosts Emiel and Erika, and prepare to take a deep dive into the science behind Nootropics Depot's industry-leading approach to health and nootropics in our very first episode of "In Search of Insight."
In this episode, we explore the function of uric acid in the body and the many ways that Tart Cherry effects it. From benefitting exercise recovery to promoting healthy sleep cycles, Tart Cherry is a game changer!