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Get more notes at https://podcastnotes.org Podcast Notes Premium Collection: Huberman and Sleep
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Intro to Sleep
Sleep cycles & Architecture: non-REM and REM play for brain domination throughout the night in 90-minute cycles – this is the standard architecture of sleep
Ratio of non-REM and REM throughout the night: the first half of the night is dominated by non-REM deep sleep; the second half of our sleep is dominated by REM sleep
Not everyone’s sleep cycles are 90 minutes: sleep architecture is fairly consistent within a person, but can be different across people
Non-REM Sleep: Non-REM deep sleep is divided into four stages, increasing in the depth of sleep: stages 1 and 2 are light stages of non-REM deep sleep; stages 3 and 4 are deep stages of non-REM deep sleep
In stages 1 and 2: the heart rate begins to drop, and brain wave activity slows down
In stages 3 and 4: the heart rate is low, cells in the cortex fire together then go silent
During non-REM deep sleep, we get autonomic restoration and regulation of heart rate and blood pressure
Hypnogogic Jerks: during stage 1 you experience mini dreams s you’re starting to drift off and can almost wake yourself up in this stage – sometimes you experience a jerk in your body as a result of loss of proprioceptive feedback
Don’t miss these notes about how Salvador Dali used the hypnogogic state to be creative (Slumber with a Key)
…
Quantity, Quality, Regularity, and Timing (QQRT): The macros of sleep
Quantity: the average adult needs between 7-9 hours of sleep per night – but the reality is more complex
Quantity alone doesn’t tell the full story
…
Carbs, Caffeine and THC
Carbs in AM vs. PM: research does seem to support that your body is better able to metabolize carbohydrates in the morning versus evening if you’re concerned about your blood sugar and metabolic health
Eating Before Bed: In gener…
Sleep Supplements
Magnesium Threonate or Glycinate, 145mg, 30-60 minutes before sleep
Magnesium chloride can be effective for bioavailability by way of muscle relaxation
Apigenin: 50mg, 30-60 minutes before sleep
Theanine: 100-400mg, 30-60 minutes before sleep (Do NOT take Theanine if you are prone to night terrors or sleepwalking)
Inositol
Glycine: 1.5-2gPhosphatidylserine will dampen cortisol response
Check out the full Momentous Huberman sleep stack & use promo code PODCASTNOTES for 15% off at checkout!
Sleep Tips
1. Do Nothing! If you are struggling with sleep and had a bad night of sleep, do not sleep in later, do not go to bed earlier, do not increase caffeine intake, do not compensate with a nap
2. Time rescheduling/sleep restriction therapy: if you are spending too much time in bed, your brain is not efficient; it’s like being in the gym for hours a day but spending most of the time scrolling on your phone – you’re not really getting a good workout like if you know you only have 45 minutes to workout
3. Don’t underestimate the importance of a winddown routine: whatever you enjoy for relaxation, build it into your regimen to help you decelerate
4. Do NOT count sheep, instead take yourself on a mental walk: counting sheep actually makes you stay awake longer; instead, get your mind off itself by going through a rudimentary walk with hyper-detail – imagine putting your shoes on, opening the door, crossing the street, imagine the signs you see, look at the flowers, etc.
5. Remove …
Monophasic sleep: Single bout of sleep in 24 hour period
Biphasic sleep: Two bouts of sleep in 24 hour period
Polyphasic sleep: …
Napping
Naps are a Double-Edged Sword: If you struggle with sleep at night, do not nap during the day in order to build up sleepiness and hopefully sleep at night
Cons of Napping: Naps remove sleep pressure (adenosine) so if you struggle with sleep, you are setting yourself up for worse sleep because you’ve removed some of the sleepiness you need
Pros of Napping: If napping does not disrupt your sleep and leaves you feeling better, go ahead and nap but be cautious of napping too late which can disrupt sleep
Are Naps Right F…
Super Charged Nap: Swig espresso right before napping + nap 20 minutes + cold water to hands and face upon waking + immediate daylight 5-10 minutes outside
3 Ways Sleep is Essential for Learning:
1: We need sleep before learning to start the initial imprint and laying the tracks; sleep before learning is critical
2: We also need sleep after learning to cement the information in our brain
3: We need sleep to integrate the new information with previously learned information we have stored
Exactly How Much an All-Nighter Impacts Memory: Pulling an all-nighter leads to deficits of up to 40% in making new memories
…
Symptoms of REM Sleep Deprivation: Paranoia, hallucination, aspects of psychosis (with enough time)
Bad Sleep, And Then: When sleep deprived, you’re excessively reactive and hypersensitive, particularly to reward-based activities – dopamine circuits are overactive when you are underslept
Sleep and Addiction: A lack of sleep is associated with addiction potential AND relapse if trying to abstain
REM Sleep Killers: Alcohol, THC
One Possible Mechanism for PTSD: The brain is trying to process the traumatic experience but fails, so the brain tries again the next night, and the next – until …
Brain Features of REM:
(1) Electrical brain wave activity in the cortex is similar to that when you are awake;
(2) There are unique pulses from the brain stem ultimately to the occipital cortex (linked to rapid eye movements);
(3) Motor regions, visual regions, memory-related structures, and emotional-related structures of the brain all light up
(4) The dorsolateral prefrontal cortex (responsible for inhibition and planning) activity is suppressed during REM
Functions of REM sleep: (1) Creativity; (2) Emotional & mental wellness – REM sleep is overnight therapy
…
(1) Consistently rehearse the notion that you will remember your dreams and you will take control of your dreams – if you do this enough, the probability you will induce lucid dreams is high
(2) Rehearse something (like flicking a light switch on and off) over and over; Then, when this appears in your dream you can take control
…
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David Deutsch: Chemical Scum that Dream of Distant Quasars | TED
In this TEDTalk from 2005, David Deutsch (@DavidDeutschOxf) was tasked with going out on a limb and saying something surprising. The result? A profound exploration titled Chemical Scum That Dream of Distant Quasars where he redefines humanity’s place in the universe and celebrates the limitless potential of human knowledge. Though the title might sound nerdy or even a bit intimidating, these Premium Podcast Notes break down every element of this groundbreaking TED Talk, revealing powerful principles of problem-solving that could transform how you see your role in fostering the endless growth of knowledge and shaping a better future.
Scott Galloway on How Stoicism Can Benefit Young Men | Daily Stoic with Ryan Holiday
Scott Galloway on "Intergenerational Theft" and why Stoicism can help young men who are struggling now more than ever. Go Premium to learn why young men are struggling, how to protect the middle class, the value of being a Nation, how to be successful, truths about money and more.
Mike Cernovich – Escaping Sam Altman’s Techno-Slavery | Zero Hour with James Poulos
Mike Cernovich discusses Sam Altman's Techno-Gnostic archetype, secular fatalism, Greco-Roman principles, consciousness, and more. This is not your average podcast and not to be missed.
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David Deutsch: Chemical Scum that Dream of Distant Quasars | TED
Is Earth Special? Two Possible Theories…
Theory #1: Earth is very untypical and uniquely suited...
“Spaceship Earth” = ...
If we destroy the ...
Theory #2: Earth is typical and human beings are not ...
“The human race is just a chemical scum on a moderate-sized planet, orbiting around a very average star in the outer suburb of ...” – Stephen Hawking
Key Takeaway: “So, especially if you regard them as deep truths to form cornerstones of your world view and inform your life-decisions, they appear somewhat in ...” – David Deutsch
Earth is Very Not Typical:“Deep, intergalactic space is completely dark. It is so dark that if you were to look at the nearest star to you, and that star were to explode as a supernova, and you were staring directly at it at the moment when its light reached you, then ...”– David Deutsch
Humans are Very Special Chemical Scum: “Therefore we are chemical scum that’s different. This chemical scum has universality. Its structure contains, with ever-increasing ...” – David Deutsch
3 pre-requisite resources for the open-ended creation of knowledge:
Matter: the growth of knowledge is a ...
Energy: the inputs required to ...
Evidence: the laws of physics saturate the ...
Resources are abundant, knowledge is scarce:If something isn’t forbidden by the ...
Our Sacred Responsibility as Humans: “Species go extinct. All the time. Civilizations end. The vast majority of all species and all civilizations that have ever existed are now history. If we want to be exceptions ...” – David Deutsch
Scott Galloway on How Stoicism Can Benefit Young Men | Daily Stoic with Ryan Holiday
The Epicenter of Today’s Problem:For the first time in the nation’s three-century history, a thirty-year-old person today is doing worse than ...
The nation is a feature, not a bug:The most successful people in tech should have more ...
Understanding Power Laws and the Pareto Principle: A very small percentage of people will ...
Advice for young people on how to be successful: Put yourself in rooms of ...
The trope “money can’t buy happiness” is a myth: Studies show that middle-income people are ...
Young Men Are In Trouble:Young men in America are ...
4x more likely to kill themselves
Four out of five suicides involve men
There is a certain amount of resentment and ...
Understanding Stoicism: Stoicism is a philosophy that teaches ...
Why Billionaires Become Billionaires (narrative violation): Generally, billionaires are good high-character people; one of ...
Emotional advice from Scott:
If something moves you, lean into that emotion and learn how to cry
Figure out a way to ...
Lean into feeling your ...
To not lean into ...
You will get to know ...
Mike Cernovich – Escaping Sam Altman’s Techno-Slavery | Zero Hour with James Poulos
The Fallacy of Pendulum Theory:There is no law of the universe that says things have to swing back and forth between ...
America has submitted to its base-lower impulses
Book recommendation: Nicomachean Ethicsby Aristotle
Many Americans have lost touch with what ...
It would be one thing if people turned away from God but...
The Source of Society's Problems:Alienation from the divine is...
Techno-Gnostics refers to a perspective or philosophy combining elements of technology with ...
The Harsh Truth About Sam Altman: “Sam Altman is a gnostic, but he doesn’t realize that he’s 2,000 years too late. Hating your body and thinking that your body is gross is not some sort of new thing.” – Mike Cernovich
“Sam Altman hates being a human and wishes he didn’t live in a body and wants to upload himself into a Warhammer machine. People like that – I think we should dismiss ...” – Mike Cernovich
Like Altman, the materialistic Soviets also hated the body and ...
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Jensen Huang – Founder of Nvidia | Founders Podcast with David Senra
What "Strategy" Actually Means:Strategy is not words; strategy is action
What "Mission" Actually Means: The Mission is the Boss. Nvidia exists to serve a mission and not for the sake of perpetuating its existence
Ship the Whole Cow: Nvidia found ways to package and sell hardware that it previously would have discarded; this helped it mitigate low-end market competition and insulate itself from the innovator’s dilemma
Complacency kills: The enemy is not the competition, but the company falling victim to complacency – both real and imagined
Jensen’s keys to success:(1) He puts in more effort than his peers and (2) He has a willingness to tolerate more suffering than those around him
History’s greatest founders spend a lot of time teaching within their organization
Founders Thread:“If you’re not spending 90% of your time teaching, then you’re not doing your job.” – James Sinegal of Costco
Founders Thread – Apple is Steve Jobs with 10,000 lives
The best founders are evangelists for their companies; examples include Steve Jobs, Palmer Luckey, and Sir James Dyson
The Whiteboard Method: Using a whiteboard is the primary form of communication in Nvidia meetings; everyone must demonstrate their thought process in real-time, and be willing to eventually erase an idea – no matter how good it is
Go Fast or Die: “You can drive great people away by making the speed of decision-making really slow. Why would great people stay in an organization where they can’t get things done? They look around and say, ‘Hey, I love the mission, but I can’t get my job done because the speed of decision-making is too slow.”
Value of A flat organizational structure(1) Enables employees to act with more independence and (2) Filters out low-performing employees who are unaccustomed to thinking for themselves
F Your Feelings: Jensen tortures people into greatness: The quality of the work is the most important thing, not people’s feelings
“I wake up every morning, look at myself in the mirror, and say: ‘You suck.’” – Jensen Huang
“I don’t like giving up on people. I’d rather torture them into greatness.” – Jensen Huang
The Speed of Light in Practice:
Break down each component task of a project and assign a target time to completion for it
Assume no delays, no queues, and no downtime so that you can set the theoretical maximum, i.e. the Speed of Light
Instead of judging performance relative to your past performance or against the competition, judge yourself against the speed of light and the law of physics
Top Five Things (T5T) email
Every employee, at all levels, sends an email with the top five things that they are working on, or the top five things they are observing in the market (customer pain points, a competitor’s strategy, new developments in technology, or project delays)
Each email contains five bullet points, and the first word in each bullet is an action word, such as finalize, build, or secure
Each department labels each email in the email’s subject line
Winston Churchill Would have Loved Twitter/X– He limited the size of memos that his staff could send him and told them that it was “slothful” not to compress your thoughts
Henry Singleton, cofounder of Teledyne, on planning:
1. Flexibility over rigid plans
2. Daily steering over long-term planning
3. Excessive planning constraints freedom of action
4. Recognize that the world is complex and avoid counterproductive planning
5. Be skeptical of the herd
Educating the Marketplace: If you are doing something brand-new, you must spend a lot of time and resources on educating the market about your new idea or invention
Dr. Brian Keating: Charting the Architecture of the Universe & Human Life | Huberman Lab
Fun fact #1: We didn’t have accurate clocks until the 1700s. Before that, keeping time on a ship or in different time zones was nearly impossible
Fun fact #2: The Gutenberg Bible was used as a standard for vision quality in the past. They would test eyesight by making people read it from a certain distance since it had a fixed font size. This was way before modern eye charts
Pineal Gland (get rid of that flouride): Most animals have a pineal gland that secretes melatonin based on light. “This is the intrinsic clock-keeping mechanism of all mammalian species and reptiles.” – Huberman
Birds have thin skulls, so light can pass right through to the pineal gland
Humans are different: Our pineal gland is buried deep in the brain, so light doesn’t reach it directly. Instead, light info gets passed from the eyes through a pathway to the pineal gland.
Gender Symmetry: Women are more symmetrical than men
Eyes Are Outside Brains: Retinas, which line the back of the eyes, are part of the central nervous system and were squeezed out of the brain during early development
Hubble made two major discoveries: that the Milky Way isn’t the entire universe, and that the universe is expanding
“The Big Bang is not the origin of time and space, it’s the origin of the first elements in the periodic table.” – Brian
The best places in the Northern Hemisphere to see spectacular nighttime views:
Yosemite High Country in August for meteor showers would be a great option
Anywhere 20-40 miles from a large city should be fine. Even in San Diego, there are two dark sky communities: Julian and Anza-Borrego Desert
Panspermia—the idea that life might’ve come from elsewhere in the universe. Basically, genetic material could’ve traveled from one astronomical object to another. This is not something scientists can prove right now, especially with the lack of life evidence elsewhere
Tools for Managing Stress & Anxiety | Huberman Lab Essentials
How breathing affects heart rate:
Inhale:
When you inhale (through the nose or mouth), the diaphragm moves down, and the lungs expand
The heart gets slightly bigger in that expanded space
This increased space causes blood to move more slowly through the heart
A group of neurons called the sinoatrial node in the heart detects the slower blood flow and sends a signal to the brain
The brain then signals the heart to speed up
A longer or more vigorous inhale will make your heart beat faster
Exhaling:
When you exhale, the diaphragm moves up, and the heart becomes smaller and more compact
Blood flows faster through the smaller heart space
The sinoatrial node detects the faster blood flow and signals the brain
The parasympathetic nervous system sends a signal back to the heart to slow down
A longer or more vigorous exhale will make your heart rate slow down
The physiological sigh: two deep inhales through the nose (no exhale in between), followed by a full exhale to the lungs empty (through the mouth) is the fastest way to calm down
Why short-term stress is good:
Pupil dilation and optical changes help enhance vision
Heart rate quickens, improving blood flow and readiness
Cognition sharpens, bringing certain brain areas online to focus better
Narrowed focus supports duration-path-outcome analysis. It allows you to evaluate your environment and decide what to do
It primes the immune system to combat bacterial or viral infections
Tool: eye dilation
Without moving your head or eyes, shift from tunnel vision to panoramic vision (see more of your surroundings)
This activates circuits in the brainstem associated with calming and reduces alertness/stress
For example: While running or cycling at max capacity or 80–90% of your maximum effort, practice dilating your gaze
Best tools to modulate long-term stress:
Regular exercise (who would’ve thought!)
Prioritizing good sleep
Using real-time tools to manage stress response (e.g., breathing exercises)
Social connection (one of the most effective ways to combat long-term stress)
Theanine (L-theanine):
Recommended dose: 100–200 mg, 30–60 minutes before sleep
Benefits:
Enhances the transition into sleep and improves sleep depth.
Increases GABA, an inhibitory neurotransmitter
Reduces activity in the forebrain, calming thinking and ruminative systems
Stress and anxiety:
Proven to significantly increase relaxation
Shown to have a minor yet notable effect on anxiety
Tyler Cowen – Humans Are The Bottleneck to AI Progress | Dwarkesh Patel
Cost disease and AI: Cost disease happens when wages rise across the board due to productivity gains in some industries, but sectors like healthcare or education, where productivity is harder to improve, still need to pay higher wages—making their costs go up
Tech diffusion is universally pretty slow: While people in the Bay Area are the smartest, most dynamic, and most ambitious, they tend to overvalue intelligence
Some kind of demoralization may materialize in the AI future: Full employment is likely to remain, but it is not clear what humans will be doing or how happy it will make us.
The Risks of Progress: War should always be the main concern during a period of rapid technological progress; throughout history, when new technologies emerge, they are turned into instruments of war, and terrible things can happen
PREMIUM:
David Deutsch: Chemical Scum that Dream of Distant Quasars | TED 2005
Scott Galloway on How Stoicism Can Benefit Young Men | Daily Stoic with Ryan Holiday
Mike Cernovich – Escaping Sam Altman’s Techno-Slavery | Zero Hour with James Poulos
FREE:
Jensen Huang – Founder of Nvidia | Founders Podcast with David Senra
Dr. Brian Keating: Charting the Architecture of the Universe & Human Life | Huberman Lab
Tools for Managing Stress & Anxiety | Huberman Lab Essentials
Tyler Cowen – Humans Are The Bottleneck to AI Progress | Dwarkesh Patel
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5 Ways Stem Cells Will TRANSFORM What It Means To Be Healthy | The Gabby Reece Show
Christian Drapeau (@stemcellchristian) is a pioneer in stem cell research. And the first to propose stem cells as the body’s innate repair system. Christian Drapeau discusses the transformative potential of stem cells in health and healing. They explore the basics of stem cells, their role in the body, the evolution of stem cell research, and the impact of aging on stem cell efficacy.
The Roman Caesars’ Guide to Ruling | Barry Strauss on The Art of Manliness with Brett McKay (#1047)
How often do you think about the Roman Empire? Lately, this question has gone viral, leaving many women wondering why their husband or boyfriend is reflecting on Roman history so often. The truth lies in the Empire’s enduring allure: its epic tales of power, war, ambition, innovation, and dramatic leadership. In these Premium Podcast Notes, we turn to historian Barry Strauss who gives a detailed overview of his book, Ten Caesars: Roman Emperors from Augustus to Constantine, unpacking the themes that make Rome’s legacy a timeless source of fascination.
Podcast Notes Book Collection: 2024 Edition (UPDATED AND COMPLETE with 200+ Books)
After reviewing all 400+ Podcast Notes we wrote in 2024, we selected a comprehensive reading list of over 200 books. Whether you’re a new parent, hopeful entrepreneur, tech geek, history buff, or just a general bookworm, there’s truly something for everyone!
Top Takeaways Of The Week
5 Ways Stem Cells Will TRANSFORM What It Means To Be Healthy | The Gabby Reece Show
Stem Cells With Age: By age 30, you’ve lost 90% of red marrow stem cells; as stem cells disappear from the body, the loss becomes increasingly apparent over time
Stem cell sources: Bone marrow, fat tissue, blood, umbilical cord
Yamanaka factor: Take old cells and turn them into cells with characteristics of young cells
Why We Lose Them: “Over the past 150 years, we’ve gained an extra 50 years of lifespan. I don’t think we have the biology to have an extra 50 years naturally with full blossoming health. We need to kind of hack and tap and leverage things in our body.” – Christian Drapeau
Stem cells from blood (like PRP) are very potent; they’re dormant so need to be ‘awakened’. This is likely the future of stem cells and relatively new to use; the task now is to learn how to isolate and grow them for use Stem cells from the umbilical cord: The most potent – but not as mainstream because of three notable concerns:
(1) Risk of contaminated stem cells is high which can lead to sepsis;
(2) They’re difficult to isolate cleanly;
(3) You can obtain genetic material from a donor who may have been a carrier for a disease that you may develop in the future
Tips to Supported Stem Cells:
Red lights might help with bodily repair, possibly by aiding blood circulation
Pulsed magnetic frequency (PMF) has been well-documents to boost stem cell frequency
Exercise releases stem cells – but this might be because if you trigger tissue damage, your body will trigger a response
Quality sleep supports the proliferation of brain stem cells
Meditation has a healing component – 20 minutes of meditation has been shown to encourage stem cell release
Plants for health: Shilajit, black seed (periodically), natto, kava (hard to source)
The Roman Caesars’ Guide to Ruling | Barry Strauss on The Art of Manliness with Brett McKay (#1047)
The Rise of Octavian/Augustus Caesar: Octavian, born Gaius Octavius, was Julius Caesar’s grand-nephew and was adopted posthumously as part of Caesar’s will — which was technically illegal, but law was pretty loose during civil war
How to Win the Game of Thrones: Augustus simply killed off a lot of his enemies, between several civil wars and the execution of about 100 Roman senators
Augustus' Expansion: Octavian added Egypt, northwestern Spain, and Switzerland to the Roman Empire
The Infamy of Nero: Nero was less interested in the empire itself and more interested in the celebrity of being Emperor
He was egotistical and also very vain about his singing and chariot racing ability
He competed in the Panhellenic Games and “won” every event
The Truth About Nero's Fiddling While Rome Burned: There’s a rumor that Nero fiddled while Rome burned, but the fiddle technically hadn’t been invented yet. However, he may have played a lyre, which is a harp-like instrument.
Marcus Aurelius, the Ivory Tower Emperor: Marcus Aurelius was a great philosopher but not a great emperor
Marcus Aurelius had no military experience or experience outside Italy, he was completely unprepared to become empowered — a common theme in the Roman Empire system
He let is son Commodus follow him as emperor
Commodus, The Villain: The first man born to be emperor
Commodus was arrogant, entitled, and irresponsible
Competed as a gladiator
He offered bread and circuses to the people but killed many senators
Eventually, the senate carries out a plot to kill Commodus
Dr. Laurie Santos: HowTo Achieve True Happiness Using Science-Based Protocols | Huberman Lab
Happiness Operates on 3 Timescales: (1) The immediate timescale of happiness; (2) The intermediate timescale of happiness where we introduce a story; (3) Meaning which is the full picture
Tips to Approach Happiness on All 3 Levels:
Engage in activities that fit with values and strengths;
Infuse strengths into work & leisure;
Do for others
Ask others for help
Extrinsic rewards: A tangible, visible reward for achieving something
Intrinsic rewards: Reward comes from within, feeling progress, purpose, etc.
On the lower end of the income spectrum, money affects happiness: If you struggle to put food on the table, keep a roof over your head – more money almost has a linear relationship with happiness
Stop being a Sad Loner: One of the biggest levers you can pull to improve happiness is to get more social connection“The two things that predict whether you’re happy or not so happy are how much time you spend with friends and family members and how much you are physical around other people. The more of that you do, the happier you’re going to be.” – Laurie Santos
Dopamine Must Be Earned, Not Given: “Be wary of any dopamine hit not preceded by effort to achieve it.” – Andrew Huberman
Prediction error: Introverts predict social connection will be negative, when in actuality they get report a great experience; extroverts predict social connection will be ok, and anticipation is high
Negativity bias: We’re built to notice the risky, potentially scary stuff; our brain goes there automatically which makes sense evolutionarily
Toxic Positivity: The notion that something is wrong if you’re feeling anything but happy or ‘good vibes’; negative emotions are a cue from our body to take action in some direction to fix
Dog vs. Cat People: If you crave unconditional love, you are probably more of a dog person; cats are more independent
Hedonic adaptation: We get used to things; you can’t be happy all the time because you become sensitized
“Every good thing in life becomes boring after some time.” – Laurie Santos
Tip: Imagine the negative things and obstacles; use worse things as a comparison to realize how good things are – don’t ruminate on it but use your imagination to appreciate what you have
Tip #2: Space out positive experiences to come back to them over time
Banister effect: Believe something is positive; be optimistic enough to think something is doable then ask yourself the question ‘what will get in the way?’ so you problem-solve
Arrival fallacy: The idea, “I’ll be happy when…” – the thing we arrive at doesn’t feel as good once we get there and we chase the next thing
Micky Malka – Building Ribbit | Invest Like the Best with Patrick O’Shaughnessy Ep. 400
Life and business principles from Micky Malka:
1. Never forget where you came from
2. Fewer decisions is best
3. Be genuine to yourself and those around you
Lessons learned from the Robinhood saga
Being the CEO is a very lonely existence
Develop and craft a flexible mindset so that you can be comfortable taking risk
When you truly understand the variables at play, you will be more comfortable with taking ‘risk’
Mistakes made in a single day can damage a company’s brand for years to come
Technologies have their own grid complexes
The electrical grid consists of towers, power meters, transformers, and more
The internet is a grid of data and knowledge
The monetary system has its own grid as well, consisting of the different financial layers and rails which include Visa, Mastercard, SWIFT, etc
Stablecoins: US dollar stablecoins are travel checks in today’s world; they are instant dollars that the individual can control and move, anytime, and for zero
Stablecoins provided people with access to US dollars who previously did not have access to dollars and who were forced to use their local (and weaker) fiat currency
Today, US-dollar stablecoins do a similar monthly volume to that of Visa and Mastercard
What Got You Here, Won't Get You There: Burn the bridge that got you here; whatever got you here will not get you to the next phase
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Get more notes at https://podcastnotes.org We live in a brave new world, one that requires modern tools. Social media algorithms are more manipulative than ever. Meanwhile, mainstream media distorts the truth, deepening public skepticism and confusion. Since 2020, much has changed — some of it irreconcilable. Those of us who can master the new landscape will thrive, but those who fail to adapt will fall further behind. That’s why Podcast Notes Premium has curated this Modern Survival Guide, offering practical mental models and insights on prioritizing truth-seeking, understanding the self in today’s society, navigating politically charged conversations, avoiding social media traps, and keeping pace with a world that seems to be moving at an unprecedented and erratic pace.
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Radiolab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------How much does knowledge cost? While that sounds like an abstract question, the answer is surprisingly specific: $3,096,988,440.00. That’s how much the business of publishing scientific and academic research is worth.
This is the story of one woman’s battle against a global network of academic journals that underlie published scientific research. In 2011, Alexandra Elbakyan had just moved home to Kazakhstan after a disappointing few years trying to study neuroscience in the United States when she landed on an internet forum where a bunch of scientists were all looking for the same thing: access to academic journal articles that were behind paywalls. That’s the moment the very simple, but enormously powerful, website called Sci Hub was born.
The site holds over 88 million articles and serves up about a million downloads to people in practically every country on the globe. We travel to Kazakhstan to meet the mysterious woman behind it all and to find out what it takes to make everything we know about anything available to anyone anywhere, for free.
Special thanks toVrindra Bhandari, Balázs Bodó, Stephen Buranyi, Ian Graber-Stiehl, Joel Joseph, Noorain Khalifa, Aparajita Lath, Steve McLaughlin, Marcia McNutt, Randy Scheckman Tanmay Singh, Deborah Harkness, Joe Karaganis, Lawrence Lessig, Glyn Moody, and Steven Press.
Episode Credits:Reported by - Eli Cohen
Reporting help from - Karishma Mehrotra
Produced by Simon Adler
with help from - Eli Cohen
Original music and sound designed by - Simon Adler
Mixing by - Jeremy Bloom
Edited by - Alex Neason
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Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Alex Hormozi is a founder, investor and an author.
Alex's Twitter has been one of my favourite sources of great insights over the last year. Today we get to go through some of my favourite lessons from him about life, human behaviour, psychology, business and resilience. This is really good.
Expect to learn how your ego is keeping you poor, why you never need to care about what anyone else thinks of you, why having a life that sucks is actually a blessing, whether most easy opportunities are just distractions, how to conquer your tiny impulses, why you are built to deal with things being hard, how to beat anyone who ever copies you and much more...
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain the biology of hair, hair growth, why hair growth slows and what cause hair to stop growing and/or “fall out.” I discuss the essential role of hair stem cells and other supporting biological factors for healthy hair growth. Then I describe various approaches (mechanical and chemical) to slow hair loss by increasing blood flow to hair stem cells, including minoxidil, tadalafil, PRP, microneedling, Botox and ketoconazole treatments. I also discuss how age-related hormone changes cause hair loss and explain the effectiveness of treatments such as caffeine, saw palmetto, growth hormone, finasteride and dutasteride. For all hair growth options, I describe potential side effects, how soon to expect results and the amount of hair regrowth to expect and I highlight effective combination treatments for hair regrowth even in hair “dead” (bald) zones. For many listeners, thinning, brittle hair, or pattern baldness are a source of anxiety and stress. This episode explains the mechanisms underlying hair regrowth tools and the science behind them so that you can evaluate potential treatments and associated side-effect profiles and select the best one(s) for you.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanHelix Sleep: https://eightsleep.com/hubermanHVMN: https://hvmn.com/hubermanROKA: https://roka.com/hubermanLMNT: https://drinklmnt.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Hair(00:04:13) Sponsors: Helix Sleep, HVMN, ROKA(00:08:04) Psychological States & Hair(00:13:19) Hair Anatomy & Stem Cells(00:26:05) 3 Phases of Hair Growth(00:35:40) Sponsor: AG1 (Athletic Greens)(00:36:55) Minoxidil & Blood Flow(00:45:37) Increase Blood Flow: Massage, Tadalafil, Platelet-Rich Plasma (PRP), Microneedling(00:56:10) Microneedling, Minoxidil & “Dead Zones”(01:00:13) Sponsor: LMNT(01:01:25) Botox Treatments(01:06:27) Androgens, Hair Growth & Pattern Hair Loss; Scalp vs. Beard Hair(01:15:46) Topical Caffeine & Slowing Hair Loss(01:21:06) IGF-1: Growth Hormone & Sermorelin; Insulin Sensitivity: Myo-Inositol(01:25:52) Iron & Hair Growth(01:27:04) 5-Alpha Reductase & Saw Palmetto; Curcumin(01:33:22) Ketoconazole & Offsetting Hair Loss(01:38:46) Topical & Oral Finasteride(01:51:00) Post- Finasteride Syndrome(01:56:01) Dutasteride(01:58:53) Mechanical & Chemical Stimulation for Hair Growth(02:02:46) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Pod of Jake: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Keith is the CEO & Co-Founder of OpenStore and a General Partner at Founders Fund. He is an experienced technology executive and entrepreneur, a prolific investor, and a self-described contrarian. Keith previously served as a General Partner at Khosla Ventures. Before that, he was COO at Square and served in influential roles at LinkedIn. He also co-founded Opendoor. Keith began his career in technology as a senior executive at PayPal. He has since invested early in many great companies including YouTube, Airbnb, Palantir, DoorDash, Stripe, Quora, Yammer, Affirm, Eventbrite, and many others. He also served as a Board Member from inception to IPO at Yelp and Xoom. Follow Keith on Twitter @rabois.
[0:00] - OpenStore's early momentum and fundraising strategy
[5:35] - How an decentralized department store could unlock eCommerce growth
[12:33] - Introducing OpenStore Drive and why it is great for Shopify store owners
[16:49] - OpenStore's horizontal approach and why Keith believes it is best
[18:41] - OpenStore’s business acquisition strategy and thoughtful process design
[24:09] - How learnings from OpenStore’s initial acquisitions have led to improvements
[28:56] - Why OpenStore’s business is resilient in various macroeconomic environments
[35:06] - Acquisition offers and accept rates as metrics and countermetrics at OpenStore
[38:45] - Introducing Gumdrop which matches long-tail influencers to long-tail SKUs
[41:40] - The advantages of aggregation that benefit OpenStore’s business model
[45:19] - Building a great company culture; finding & developing undiscovered talent
[51:11] - The most high-leverage activities Keith allocates time to as OpenStore's CEO
homeofjake.com
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------This week, we’re delighted to welcome Ed Latimore back for his second Infinite Loops appearance.
Ed is a best-selling author, former professional heavyweight boxer, competitive chess player, Physics graduate, father, and husband. He joins us to discuss stoicism, progress & pain, demonstrating authenticity, being liked vs. being respected, and a whole lot more.
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, my guest is Elissa Epel, Ph.D., professor and vice chair of the department of psychiatry at the University of California San Francisco (UCSF) and the author of a new book entitled The Stress Prescription. We discuss her work showing how stress impacts mood, eating behavior, mental health, physical health, and aging. She explains stress intervention tools using “top-down” techniques (e.g., radical acceptance, mindfulness, reframing), body-based methods (e.g., breathwork) including the Wim Hof Method, exercise, meditation, body scans, and environmental shifts proven to help people cease unhealthy rumination patterns. We discuss how stress can positively impact psychology and sense of purpose, how stress affects cellular aging, how our narratives of stressful events impact our mood and biology, and how to effectively reframe stress. She explains science-based techniques to break stress-induced cycles of craving and overeating and thereby improve insulin sensitivity and metabolic health. Dr. Epel provides a wide range of tools shown to be effective in reducing stress and improving various aspects of our health.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanThesis: https://takethesis.com/hubermanEight Sleep: https://eightsleep.com/hubermanHVMN: https://hvmn.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dr. Elissa Epel(00:02:17) Sponsors: Thesis, Eight Sleep, HVMN, Momentous(00:06:18) Stress; Effects on Body & Mind(00:12:50) Tools: Overthinking & Stress(00:15:37) Acute, Moderate & Chronic Stress, Breathing(00:21:23) Stress Benefits, Aging & Cognition; Stress Challenge Response(00:31:04) Sponsor: AG-1 (Athletic Greens)(00:32:19) Tool: Shifting Stress to Challenge Response, “Stress Shields”(00:37:400 Stress, Overeating, Craving & Opioid System(00:48:55) Tools: Breaking Overeating Cycles, Mindfulness(00:54:44) Soda & Sugary Drinks(01:00:51) Smoking, Processed Food & Rebellion(01:05:29) Sponsor: InsideTracker(01:06:47) Tools: Mindfulness, Pregnancy & Metabolic Health(01:14:11) Body Scan & Cravings(01:17:28) Tool: Meditation & Aging; Meditation Retreats(01:23:35) Meditation, Psychedelics & Neuroplasticity(01:26:02) Mitochondrial Health, Stress & Mood(01:29:49) Chronic Stress & Radical Acceptance, “Brick Wall”(01:37:57) Tool: Control, Uncertainty(01:45:25) Stress Management, “Skillful Surfing”(01:50:25) Narrative, Purpose & Stress(01:52:49) Breathwork, Wim Hof Method, Positivity & Cellular Aging(02:03:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
The Underworld Podcast✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------The biggest drug cartel in the world isn't Mexican, or Colombian. It's Asian. Buried deep in the Burmese jungle are networks of cutting edge meth labs, guarded by rebels and run by kingpins so powerful they make El Chapo look like a corner boy. In 2019, Underworld cohost Sean Williams went looking for one of the billion dollar meth labs spending months on the Mekong, in lawless casinos and hunting a drug industry bigger than any other on earth...and now he's a dad!Learn more about your ad choices. Visit megaphone.fm/adchoices
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain how dopamine dynamics — meaning changes and interactions between our baseline and peak levels of dopamine drive our cravings and sense of motivation. I also explain how to leverage dopamine dynamics to overcome procrastination. I cover behavioral, cognitive, nutrition-based and supplementation-based tools to optimize baseline and peak dopamine levels to ensure a persistently motivated state. I also discuss how to boost motivation when you are in a rut, why you might not want to stack behaviors/substances that spike dopamine and how build and maintain a “growth mindset” for pursuing goals of any kind. Dopamine is an incredibly powerful neuromodulator involved in basic functions (e.g., hunger, romantic attraction, etc.) and feats of cognitive and physical performance; by understanding the dynamics of dopamine, listeners ought to be better positioned to overcome procrastination, maintain motivation, and improve confidence.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanHelix Sleep: https://helixsleep.com/hubermanWHOOP: https://join.whoop.com/hubermanROKA: https://roka.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dopamine(00:02:32) Sponsors: Eight Sleep, WHOOP, ROKA, Momentous(00:06:27) Dopamine Brain Circuits (00:14:53) Goals & Addiction(00:17:13) Dopamine Dynamics, “Wave Pool” analogy(00:20:28) Craving, Motivation, Pursuit & Reward Prediction Error(00:28:26) Sponsor: AG1 (Athletic Greens)(00:29:40) Feedback Cues & Reward Contingent Learning, “Scoreboard”(00:37:40) Addiction; Pleasure & Pain Imbalance(00:44:55) Dopamine Release & Addictive Substances/Behaviors(00:50:43) Addiction Recovery, Binding Behaviors(00:53:25) Tools: Maintain Baseline Dopamine Levels(01:02:08) Sponsor: InsideTracker(01:03:26) Tool: Deliberate Cold Exposure & Dopamine(01:09:38) Prescriptions & Supplementation: L-Tyrosine, Mucuna Pruriens(01:18:58) Dopamine Trough Recovery, Postpartum Depression(01:23:31) Dopamine Dynamics, “Dopamine Stacking”; Intrinsic Motivation(01:38:10) Making Effort the Reward, Growth Mindset(01:41:49) Tool: Overcome Procrastination(01:52:16) Tool: Meditation & Procrastination(01:57:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social MediaTitle Card Photo Credit: Mike BlabacDisclaimer
Starting Greatness with Mike Maples: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Startup founders dealt with uncertainty, stress and trauma in the wake of the run on Silicon Valley Bank, but the most important lessons from this crisis never showed up in social media. In this lesson of greatness, Mike Maples, Jr of FLOODGATE calls on the actions of a variety of founders who showed incredible courage and competence to showcase three crucial lessons for founders for how to deal with another potential crisis: Scenario planning, financial agility, and crisis communication.
Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Photographer, author, and visionary Kevin Kelly talks about his book Excellent Advice for Living with EconTalk's Russ Roberts. His advice includes how to have a deep conversation, why it's better to control time than money--and whether, in the end, we should give advice in the first place. Other topics of discussion include the right object of our aspirations, the reason for optimism when it comes to technology, and why Kelly is not worried about AI.
HBR IdeaCast✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------How do you solve the world's toughest problems? Or find the next big thing in tech? Lots organizations fail to explore and take big bets on new ideas because they can't tolerate the mess of experimentation and the fear of failure. At X, Alphabet's dedicated innovation factory, they don't have that problem, and Astro Teller, Captain of Moonshots at X, can explain why. Undertaking projects on everything from rural communication to ocean health to machine learning, he and his teams operate with different creative mindsets and decision-making principles than many of us. He spoke with host Alison Beard at HBR at 100: Future of Business live virtual conference.
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 436: In a special Friday episode, Shaan Puri (@ShaanVP) gives a special masterclass on his pitch deck that has raised millions from investors. Go to the MFM YouTube channel to see examples.Want to see more MFM? Subscribe to the MFM YouTube channel here.SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com-----Links: shaanpuri.com/deck Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.------Show Notes:(01:35) - Title(05:41) - Data/personal story(07:30) - Future vision(10:30) - Hero metric(14:15) - Track record(16:30) - Sweeten the pot-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Sam Altman is the CEO of OpenAI, the company behind GPT-4, ChatGPT, DALL-E, Codex, and many other state-of-the-art AI technologies. Please support this podcast by checking out our sponsors:- NetSuite: http://netsuite.com/lex to get free product tour- SimpliSafe: https://simplisafe.com/lex- ExpressVPN: https://expressvpn.com/lexpod to get 3 months freeEPISODE LINKS:Sam's Twitter: https://twitter.com/samaOpenAI's Twitter: https://twitter.com/OpenAIOpenAI's Website: https://openai.comGPT-4 Website: https://openai.com/research/gpt-4PODCAST INFO:Podcast website: https://lexfridman.com/podcastApple Podcasts: https://apple.co/2lwqZIrSpotify: https://spoti.fi/2nEwCF8RSS: https://lexfridman.com/feed/podcast/YouTube Full Episodes: https://youtube.com/lexfridmanYouTube Clips: https://youtube.com/lexclipsSUPPORT & CONNECT:- Check out the sponsors above, it's the best way to support this podcast- Support on Patreon: https://www.patreon.com/lexfridman- Twitter: https://twitter.com/lexfridman- Instagram: https://www.instagram.com/lexfridman- LinkedIn: https://www.linkedin.com/in/lexfridman- Facebook: https://www.facebook.com/lexfridman- Medium: https://medium.com/@lexfridmanOUTLINE:Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.(00:00) - Introduction(08:41) - GPT-4(20:06) - Political bias(27:07) - AI safety(47:47) - Neural network size(51:40) - AGI(1:13:09) - Fear(1:15:18) - Competition(1:17:38) - From non-profit to capped-profit(1:20:58) - Power(1:26:11) - Elon Musk(1:34:37) - Political pressure(1:52:51) - Truth and misinformation(2:05:13) - Microsoft(2:09:13) - SVB bank collapse(2:14:04) - Anthropomorphism(2:18:07) - Future applications(2:21:59) - Advice for young people(2:24:37) - Meaning of life
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Visionary technology and business leader Nathan Myhrvold just might be the most interesting person in the world, and in this episode of The Knowledge Project he dives deep into some of the most pressing questions facing our world today. Where will technology take us in the future? Should we trust artificial intelligence? Where have we gone wrong in protecting our planet? How do we reverse the effects of what we’ve already done? Myhrvold answers all these and much, much more. Myhrvold is a prominent scientist, technologist, inventor, author, and food photographer, and the former Chief Technology Officer at Microsoft. He’s also the co-founder of patent portfolio developer Intellectual Ventures, the principal author of the culinary book Modernist Cuisine: The Art and Science of Cooking, part of a team that won first place at the World Barbecue Championships, and he completed his postdoctoral fellowship under legendary theoretical physicist Stephen Hawking. --
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Nudge - Marketing Science Simplified✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Ever worried about someone stealing your phone at the beach? Well, there’s one thing you can do to make your phone 4x safer. It involves using a psychology-inspired principle to change behaviour. On this show, you’ll learn what it is, and why it’s important to marketers. Today, Nancy Harhut and I will cover five more marketing principles. Plus, I’ll share my real-world experiments to reveal which principles work, and which don’t. Try HubSpot for free: https://hubspot.sjv.io/jWq4k6Consistency experiment: https://bit.ly/3sABZTUInput bias experiment: https://bit.ly/3sEPFgCFraming experiment: https://bit.ly/3TMKgA2Information gap experiment: https://bit.ly/3DiGasAAuthority bias experiment: https://bit.ly/3sF0G1ANancy’s book: https://amzn.to/3DZTl23Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-listTake my marketing course: https://science-of-marketing.teachable.com/
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, my guest is Peter Attia, M.D. He completed his medical and advanced training at Stanford University School of Medicine, Johns Hopkins School of Medicine and the National Institutes of Health (NIH). Dr. Attia is host of the health and medicine podcast, The Drive, and the author of a new book, “Outlive: The Science & Art of Longevity,” which examines disease prevention and healthy aging, including emotional health. He explains the leading causes of death worldwide and how to measure one’s risk of death and mitigate each risk factor. Dr. Attia shares how, in addition to blood-based markers of lipids and hormones, there are behavioral measures and interventions, and key aspects of emotional health (i.e., relationships, emotional stability, purpose, etc.) that fundamentally impact our physical health and longevity, and how to assess and adjust our emotional health. This episode is rich with actionable information related to disease screening and biomarker testing, nutritional, exercise, behavior and prescription-based tools that area useful to all people regardless of age, male or female, and that can significantly improve vitality, health and lifespan.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanEight Sleep: https://eightsleep.com/hubermanLMNT: https://drinklmnt.com/huberman HVMN: https://hvmn.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dr. Peter Attia(00:03:22) Sponsors: Eight Sleep, LMNT, HVMN, Momentous(00:07:34) Lifespan vs. Healthspan(00:10:54) “4 Horseman of Death”, Diseases of Atherosclerosis(00:14:44) Tool: Hypertension & Stroke, Blood Pressure Testing (00:23:14) Preventing Atherosclerosis, Smoking & Vaping, Pollution(00:32:24) Sponsor: AG1 (Athletic Greens)(00:33:29) Cholesterol, ApoB(00:42:21) Cholesterol Levels, LDL & ApoB Testing(00:49:29) ApoB Levels & Atherosclerosis, Causality(01:01:06) ApoB Reduction, Insulin Resistance, Statins, Ezetimibe, PCSK9 Inhibitors(01:12:30) Monitoring ApoB(01:17:12) Sponsor: InsideTracker(01:18:30) Reducing Blood Pressure, Exercise & Sleep(01:20:50) High Blood Pressure & Kidneys(01:23:11) Alcohol, Sleep & Disease Risk(01:31:21) Cancer & Cancer Risks: Genetics, Smoking & Obesity(01:39:47) Cancer Screening & Survival(01:44:17) Radiation Risks, CT & PET Scans(01:48:48) Environmental Carcinogens(01:52:11) Genetic & Whole-Body MRI Screening, Colonoscopy(01:58:47) Neurodegenerative Diseases, Alzheimer’s Disease, ApoE(02:08:08) Alzheimer’s Disease & Amyloid(02:13:58) Interventions for Brain Health, Traumatic Brain Injury (TBI)(02:21:26) Accidental Death, “Deaths of Despair”, Fentanyl Crisis(02:31:20) Fall Risk & Stability, 4 Pillars of Strength Training(02:41:05) Emotional Health(02:53:45) Mortality & Preserving Relationship Quality(03:02:20) Relationships vs. Outcomes, Deconstructing Emotions(03:09:34) Treatment Centers, Emotional Processing & Recovery(03:16:34) Tool: Inner Monologue & Anger, Redirecting Self-Talk(03:27:37) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In a special episode of My First Million, Shaan (@ShaanVP) talks about the nine things he learned from Emmett Shear - CEO of Twitch - who resigned today.Want to see more MFM? Subscribe to the MFM YouTube channel here.SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
What Got You There with Sean DeLaney: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Kyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)
Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!). In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering. About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews). Kyle's 10 Most Life Changing Ideas Ikigai 2.0 Guidebook Watch on YouTube JOIN ME for 2 LIVE VIRTUAL EVENTS!
Live Podcast with David Senra, Host of Founders Podcast on March 15th at 2pm ET!
Register HERE, spots are limited and even if you can’t attend live if you register you’ll receive a video of the interview & Q&A!
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Learning Leader Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Text Hawk to 66866 to become part of "Mindful Monday." Join 10's of thousands of your fellow learning leaders and receive a carefully curated email from me each Monday morning to help you start your week off right...
Full show notes at www.LearningLeader.com
Twitter/IG: @RyanHawk12 https://twitter.com/RyanHawk12
David Lieberman, Ph.D., is a renowned psychotherapist and the author of eleven books, including the New York Times bestsellers Get Anyone to Do Anything and Never Be Lied to Again. He has trained personnel in the U.S.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, my guest is Satchin Panda, PhD, professor and the director of the Regulatory Biology Laboratories at the Salk Institute for Biological Studies. We discuss his lab’s discovery that “time-restricted eating” (TRE) aka intermittent fasting, is beneficial effects for metabolic health and longevity. Dr. Panda explains how TRE, and also longer fasts, can positively impact obesity, diabetes, cardiovascular health, age-related chronic diseases, and improve mood and cognitive performance. He also describes how the timing of eating, light exposure and exercise that ~50% of all people engage in, negatively impacts their health and explains how specific simple adjustments to these can positively shift their subjective feelings of health and biomarkers of cardiovascular function, glucose regulation and metabolism. We discuss how our circadian behaviors, which include our patterns of eating, sleeping and socializing, have an enormous impact on our biology, mood and health and how by simply confining our calorie consumption to a semi-regular daily window, can positively impact our physical health, mental health and longevity.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanHVMN: https://hvmn.com/hubermanEight Sleep: https://eightsleep.com/huberman Thesis: https://takethesis.com/huberman Momentous: https://www.livemomentous.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanTimestamps(00:00:00) Dr. Satchin Panda(00:03:02) Sponsors: HVMN, Eight Sleep, Thesis, Momentous(00:07:24) Time-Restricted Eating (TRE), Calorie Restriction (CR) & Health (00:14:38) Mealtimes & Circadian Clock(00:21:34) Circadian Rhythm, Meal Anticipation, Digestion(00:25:28) Breaking a Fast, Burning Fat (00:32:49) Sponsor: AG1 (Athletic Greens)(00:34:04) CR, Time Restricted Eating, Circadian Rhythm & Longevity(00:47:20) Gender, Hormones & CR; Relative Energy Deficient in Sports (REDS)(00:52:40) Physical Activity, Nutrition & Feeding Window(00:59:04) Nutrition Timing, Quality & Quantity; Low- Carbohydrate Diet (01:03:00) Caffeine, Nighttime Socialization, Fire, Breakfast(01:15:07) Sponsor: InsideTracker(01:16:20) Circadian Rhythm, “Night Owls” & Genetics (01:26:37) Morning vs. Nighttime Discussions, “Me Time” (01:30:08) Light Sensitivity & “Night Owls”; Puberty, Melatonin(01:36:05) Shift Workers, Health & Disease(01:45:43) Artificial Lights, Young Adults & Sleep, Metabolic Dysfunction (01:50:59) Firefighters, Sleep & TRE; Cardiovascular Health, Blood Glucose(02:05:18) Shift Workers & Sleep; Alcohol & Caffeine(02:09:15) 12- Hour Feeding Window for Adults & Children, Sleep(02:22:10) Meal Timing(02:25:20) “Complete Fast”, Longer Fasts, Physical Health & Mental Health(02:28:12) “Fat Fasting”, Blood Glucose & Insulin (02:31:57) Fasting, Metformin, Rapamycin & Longevity; Human Applicability?(02:39:14) Circadian Rhythm & Metabolism(02:41:36) Ontime Health App, Circadian Clock App(02:46:17) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Invest Like the Best: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest this week is Trae Stephens. Trae is a partner at Founders Fund and co-founder and Executive Chairman of Anduril. Trae’s philosophy can be boiled down to finding good quests, which has led him to investing in businesses that work closely with the government on societally important issues. Clearly, that extends to co-founding Anduril and I would highly recommend listening to my Business Breakdowns episode on Anduril if you haven’t already. In this conversation, we discuss the importance of lobbyists, why the high-tech defense firms of the past became stale, and how he hunts for disagreeableness in founders. Please enjoy my conversation with Trae Stephens.
For the full show notes, transcript, and links to mentioned content, check out the episode page here.
Listen to Founders Podcast
Founders Episode 136 - Estee Lauder
Founders Episode 288 - Ralph Lauren
This episode is brought to you by Tegus, the modern research platform for leading investors. I’m a longtime user and advocate of Tegus, a company that I’ve been so consistently impressed with that last fall my firm, Positive Sum, invested $20M to support Tegus’ mission to expand its product ecosystem. Whether it’s quantitative analysis, company disclosures, management presentations, earnings calls - Tegus has tools for every step of your investment research. They even have over 4000 fully driveable financial models. Tegus’ maniacal focus on quality, as well as its depth, breadth and recency of content makes it the one-stop, end-to-end research platform for investors. Move faster, gather deep research to build conviction and surface high-quality, alpha-driving insights to find your differentiated edge with Tegus. As a listener, you can take the Tegus platform for a free test drive by visiting tegus.co/patrick.
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Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
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Show Notes
[00:03:17] - [First question] - Why Trae thinks most high-margin businesses are bad for society
[00:04:28] - What would he change to impact energy technology most if he were in charge
[00:06:18] - His investing focus on dynamism and mission-driven tech companies
[00:09:42] - Analyzing why relatively few people strive to make society-level advancements
[00:11:35] - What he’s done as a parent to enable his kids to develop passions
[00:12:41] - The most noteworthy adventures in his career
[00:14:41] - Founding Anduril and what it taught him about the tech industry
[00:18:40] - The cutting-edge of defense technologies today
[00:21:29] - What Shyam Sankar of Palantir taught him about defense tech
[00:23:34] - Why some of the biggest defense tech companies have stopped innovating
[00:28:29] - What he and Anduril have learned about sales and scaling in the public sector
[00:32:12] - Where lobbyists and decision makers play in to defense tech business models
[00:35:22] - His take on Peter Thiel’s notion that competition should be avoided
[00:38:24] - The importance of being psychologically disagreeable when building a start-up
[00:39:54] - The origin story that stands out the most from companies he has interviewed
[00:41:12] - How he developed an investor mindset on his unorthodox path to the venture world
[00:43:57] - What he has learned from playing supporting roles and aligning with great leaders
[00:46:11] - Important but uncommon lessons about entrepreneurship
[00:48:21] - Venture investing lessons he’s learned from Lauren Gross
[00:50:00] - His first VR project and aspirations for the future of VR
[00:54:50] - The role of religion and spirituality in his business philosophies
[00:59:13] - Why he tries to capitalize on morality as opposed to sin
[01:03:57] - The kindest thing anyone has ever done for him
Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- View the Show Notes Page for This Episode
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In this “Ask Me Anything” (AMA) episode, Peter focuses the discussion on two topics getting a lot of attention recently. He first dives deep into GLP-1 agonists, most notably semaglutide and tirzepatide, which originally came to market as diabetes drugs but are now being studied and prescribed for weight loss. He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them. Next, Peter discusses how metformin, another drug originally brought to market for diabetes management, gained popularity as a potential longevity drug even for non-diabetics. Peter gives his take on this possibility and reviews data from a more recent study investigating the question of whether metformin should be used for general “geroprotection.”
If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #45 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.
We discuss:
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Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In your journey towards becoming stronger, fitter, and healthier, there often comes a point where you wonder if taking some supplements will help your progress along. But what fitness supplements are actually effective and worth investing in?
Here to answer that question is Layne Norton, a powerlifter and doctor of nutritional science who has a passion for debunking health-related myths and promoting evidence-based recommendations. He’s also, full disclosure, the owner of a supplement company himself. But I don’t have any financial connection to Layne’s company and we keep this conversation neutral and high-level. In our conversation, Layne argues that there are three top-tier research-backed supplements to consider — whey protein, creatine, and caffeine — and we unpack how to use each of them for optimal results. We discuss whether plant proteins are sufficient for building muscle, whether it’s true that creatine causes bloating, acne, and hair loss, how to best time your caffeine intake to energize your workouts, and much more. At the end of our conversation, Layne shares some additional supplements that seem promising for enhancing your health and fitness.
Resources Related to the Episode* Layne’s previous appearance on the AoM podcast: Episode #475 — How to Lose Weight, and Keep It Off Forever * Layne’s supplement company: Outwork Nutrition * AoM Article: A Primer On Muscle-Building Supplements — Which Work and Which Don’t? * AoM Article: Creatine — A Primer on Its Benefits and Use * AoM Article: How to Use Caffeine to Optimize Your Workouts * AoM Article: Chugging Your Protein — It’s Whey Easier Than You Think * AoM Podcast #285: The Real Science of Nutrition and Supplements
Connect With Layne Norton* Layne on Instagram * Layne‘s website
A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------With every new technology, some jobs are lost while others are gained. People often focus on the former, but in this episode we chose to highlight the latter – a highly creative role that emerges alongside AI: the prompt engineer.
Until AI can close the loop of its own, each tool still requires a set of prompts. Just like a composer feeds an instrument the notes to play, a prompt engineer feeds an AI a map of what to produce. And if we know anything from music it’s that composing great music takes great skill!
In this episode we explore the emerging importance of prompting with Guy Parsons, the early learnings of how to do it effectively, and where this field might be going.
Will the prompt engineer be more like the highly sought after DevOps engineer, or a proficiency like Excel that you find on every resume? Listen in to hear Guy’s take.
Interested in the prompt competition? Email us at podpitches@a16z.com.
Resources:
DALL-E 2 Prompt Book: https://dallery.gallery/the-dalle-2-prompt-book/
Find Guy on Twitter: https://twitter.com/GuyP
Guy’s combining image experiment: https://twitter.com/GuyP/status/1612880405207580672
Guy’s amorphous prompt experiment: https://twitter.com/GuyP/status/1608475973300948993
Guy’s space duck: https://twitter.com/GuyP/status/1601342688225525761
Prompt base: https://promptbase.com/
Lexica: https://lexica.art/
Topics Covered:
0:00 - Introduction
01:49 - DALL-E 2 Prompt Book
05:29 - Parallel skills
06:51 - 80/20 prompting
10:16 - New ways of prompting
13:44 - Pulling the AI slot machine
18:09 - Comparing models
21:04 - Requested features
26:34 - Learning with AI
27:58 - Practical use cases
32:08 - A top 1% prompt engineer
36:17 - The most popular images
Stay Updated:
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
Ten Percent Happier with Dan Harris: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- Dan flies to Dharamsala, India to spend two weeks in the orbit of His Holiness the Dalai Lama. This is the first installment of a five-part audio documentary series, something we’ve never done before now. Over the course of the episodes, we talk to His Holiness about practical strategies for thorny dilemmas, including: how to get along with difficult people; whether compassion can cut it in an often brutal world; why there is a self-interested case for not being a jerk; and how to create social connection in an era of disconnection.We also get rare insights from the Dalai Lama into everything from the mechanics of reincarnation to His Holiness’s own personal mediation practice.
In this first installment, Dan watches as a young activist directly challenges His Holiness: In a world plagued by climate change, terrorism, and other existential threats, is the Dalia Lama’s message of compassion practical — or even relevant?
Full Show Notes: https://www.tenpercent.com/podcast-episode/dalai-lama-guide-538
Other Resources Mentioned:
Additional Resources:
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 427: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) speak to Ken Rideout (@KenRideout_), one of the world's best masters runners, successful businessmen and entrepreneur. Ken talks about how he overcame addiction, built a lucrative career, forged mental and physical toughness, and where that's going to take him in the years to come.Want to see more MFM? Subscribe to the MFM YouTube channel here.SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com-----Links: Teddy Atlas Podcast Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.------Show Notes:(00:23) - Why Ken is blowing up(12:25) - His finance background(23:45) - Ken's Struggles with Addiction(25:40) - How he got into running/media(31:25) - Who are the toughest people you have met?(38:20) - How to deal with adversity(41:50) - Story of Ken talking smack to Lance Armstrong(44:30) - How does he make money?(53:35) - Does this level of activity increase longevity?-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I discuss our body’s most vital and essential nutrient—water. I explain the structure of water and how it is used by the cells and tissues of our body, how much water we each need to drink and when in order to optimize our mental focus and physical performance; and I include how exercise, humidity, heat, and caffeine affect our hydration needs. I explain how temperature and pH influence water’s physical properties and if there is any scientific basis for drinking so-called “pH water” or “alkalized water” to improve health. I explain how to test your tap water for contaminants (e.g., endocrine disruptors) and the documented problems with fluoride in drinking water. I provide options for filtering drinking water and describe different water types (e.g., reverse osmosis, hydrogen-enriched, electrolyzed reduced, deuterium depleted, etc.). Since the human body is mostly water (55-80% depending on one’s age) and water has essential roles in health, disease and cellular function, everyone ought to benefit from understanding how best to clean our tap water, hydrate effectively and in some cases, adjust the type of water we drink to allow our brain and body to function optimally in regard to health and performance.For recommended water filters, tests and the full show notes, please visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanThesis: https://takethesis.com/hubermanHVMN: https://hvmn.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Water(00:03:33) Tool Deliberate Cold Exposure, Immersion & Showers Mood & Fat Loss(00:15:26) Sponsors: LMNT, Thesis, HVMN, Momentous(00:19:27) Water: Physical Properties & Chemistry(00:26:32) Bonds & Water Phases, “Structured Water”(00:34:07) Body, Cells & Water(00:36:22) AG1 (Athletic Greens)(00:37:37) Water as a Solvent, Temperature & pH(00:41:49) Water Transport in Cells, Aquaporin Channels(00:49:46) Alkaline/pH Water; Temperature, pH & Water Transport(00:55:14) Water Cellular Function, Reactive Oxygen Species (ROS) & Antioxidants(01:01:20) Sponsor: InsideTracker(01:02:38) Tool: Baseline Hydration(01:11:35) Tool: Hydration & Exercise, Galpin Equation(01:15:40) Tool: Hydration, Sauna, Humidity & Sweat; Thirst, Caffeine(01:19:15) Hydration; Cognitive & Physical Performance (01:23:53) Tool: Water Filtration; Nighttime Urination(01:29:35) Tap Water Tests, Disinfection Byproducts (DBPs), Fluoride & Thyroid Health(01:37:18) Tool: Water Filters(01:44:18) Tool: Resting Tap Water & Sediment(01:48:13) Tool: “Hard Water”; Magnesium, Calcium & Cardiovascular Health(01:53:40) Water Temperature(01:56:42) Water Types: Distilled, Reverse Osmosis, Hydrogen-Enriched(02:03:26) Hydrogen-Enriched Water, Magnesium, Optimize Hydration(02:11:13) Tool: Molecular Hydrogen Tablets, Water pH(02:14:05) Structured Water(02:16:39) Tool: Water Pipes, Faucet Filter(02:19:42) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, my guest is Oded Rechavi, Ph.D., professor of neurobiology at Tel Aviv University and expert in how genes are inherited, how experiences shape genes and remarkably, how some memories of experiences can be passed via genes to offspring. We discuss his research challenging long-held tenets of genetic inheritance and the relevance of those findings to understanding key biological and psychological processes including metabolism, stress and trauma. He describes the history of the scientific exploration of the “heritability of acquired traits” and how epigenetics and RNA biology can account for some of the passage of certain experience-based memories. He discusses the importance of model organisms in scientific research and describes his work on how stressors and memories can be passed through small RNA molecules to multiple generations of offspring in ways that meaningfully affect their behavior. Nature vs. nurture is a commonly debated theme; Dr. Rechavi’s work represents a fundamental shift in our understanding of that debate, as well as genetic inheritance, brain function and evolution.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanROKA: https://roka.com/hubermanHVMN: https://hvmn.com/hubermanEight Sleep: https://eightsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dr. Oded Rechavi(00:02:08) Sponsors: ROKA, HVMN, Eight Sleep(00:06:04) DNA, RNA, Protein; Somatic vs. Germ Cells(00:14:36) Lamarckian Evolution, Inheritance of Acquired Traits(00:22:54) Paul Kammerer & Toad Morphology(00:28:52) AG1 (Athletic Greens)(00:30:06) James McConnell & Memory Transfer(00:37:31) Weismann Barrier; Epigenetics (00:45:13) Epigenetic Reprogramming; Imprinted Genes (00:50:43) Nature vs. Nurture; Epigenetics & Offspring(00:59:06) Generational Epigenetic Inheritance (01:09:03) Sponsor: InsideTracker(01:10:20) Model Organisms, C. elegans(01:21:50) C. elegans & Inheritance of Acquired Traits, Small RNAs(01:26:02) RNA Interference, C. elegans & Virus Immunity(01:34:13) RNA Amplification, Multi-Generational Effects(01:38:41) Response Duration & Environment(01:47:50) Generational Memory Transmission, RNA(01:59:36) Germ Cells & Behavior; Body Cues(02:04:48) Transmission of Sexual Choice(02:11:22) Fertility & Human Disease; 3-Parent In Vitro Fertilization (IVF); RNA Testing(02:17:56) Deliberate Cold Exposure, Learning & Memory(02:29:26) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Aarthi and Sriram's Good Time Show✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, the gang gets back together! Marc Andreessen and Steven Sinofsky are back to talk about all things AI. We cover the rise of ChatGPT, Bing's AI powered chat Sydney, AI ethics, sentience, whether AI will take over jobs, the economic impact, AI startups vs tech incumbents, and whether it is time for AI to become sentient. This was an incredibly fun episode! Marc Andreessen is an American entrepreneur, venture capital investor, and software engineer. He is the co-author of Mosaic, the first widely used web browser; co-founder of Netscape; and co-founder and general partner of Silicon Valley venture capital firm Andreessen Horowitz. Steven Jay Sinofsky is a former president of the Windows Division at Microsoft. He was responsible for the development and marketing of Windows, Internet Explorer, and online services such as Outlook.com and SkyDrive.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode 6 of a 6-part series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton, he explains optimal nutrition, hydration and supplementation to achieve your fitness goals. We cover macronutrient guidelines, when to eat relative to training and training fasted versus fed. Dr. Galpin describes proper hydration for before and during exercise, how dehydration and/or low electrolyte concentrations impede physical and mental performance. He discusses what supplements work best for fitness and performance, how to decide which to take, if any, and when to take them. He also shares high-impact, lower-cost supplements and nutrition recommendations to benefit performance, recovery, and sleep. This episode also includes an audience Q&A. Overall, it is an in-depth but clear discussion of nutrition strategies and supplements that can help anyone improve their level of fitness physical and mental performance.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLevels: https://levels.link/hubermanLMNT: https://drinklmnt.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Nutrition & Supplementation(00:05:16) Creatine Supplementation, Muscle & Cognitive Function, Loading Phase(00:16:51) Sponsors: Momentous, Levels, LMNT(00:20:31) Dehydration, Overhydration, Night Urination(00:35:37) Tool: Hydration, Caffeine & Electrolytes(00:41:22) Tool: Sweating, Salt & Performance(00:48:57) AG1 (Athletic Greens)(00:49:49) Galpin Equation for Hydration & Exercise, Focus(00:55:28) Tool: 5 Steps to Optimize Hydration, Sipping Water, W.U.T. Status, Salt(01:10:58) Electrolytes, Carbohydrates & Exercise(01:15:44) Sponsor: InsideTracker(01:16:47) Training Fasted versus Fed, Caffeine, Carbohydrate Timing(01:25:13) Caffeine & Endurance(01:31:20) Citrulline, Beet Root Juice & Performance; Alpha-GPC & Focus, Nootropics(01:35:43) Rhodiola, Cortisol & Fatigue(01:39:55) Tool: Supplement Formulations(01:47:31) Supplements, Dependency & Root Cause; Foundational Behaviors(01:57:44) Acute vs. Chronic Effects, Supplements & Gut Microbiome(02:02:33) Tool: Sleep Environment, Absolute Rest(02:11:03) Tools: Sleep & Disturbances, Inositol(02:20:03) Tool: “Fitness Fatigue” Model, Taper, Anti-Inflammatory Supplements(02:26:33) Exercise Recovery: Curcumin, Omega 3s, Glutamine, Nutrition, Vitamins(02:39:27) Intermittent Fasting, Training & Keto Diets; GABA(02:43:39) Carbohydrate Loading; Amino Acid Supplements; “Anabolic Window”(02:47:23) Garlic; Tart Cherry Extract; Examine.com(02:51:50) Fitness Testing, Training Programs; Exercise Recovery(03:04:13) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In the third installment in a series of episodes, The Knowledge Project curates essential segments from five guests revolving around one theme: leadership. This episode helps put a unique definition on leadership and examines whether or not good leaders are context-dependent, the differences between a great leader and an average leader, how great leaders should balance feedback, the difference between being right and doing right, a playbook for managing teams, and the importance of radical candor.
The guests on this episode are author Jim Collins (Episode 61, 110), author and leadership expert Jennifer Garvey Berger (Episode 43), co-founder of the Admired Leadership Institute Randall Stutman (Episode 96), the President and COO of Athletic Greens Kat Cole (Episode 117), the former CEO of Ford Alan Mulally (Episode 151), and co-founder of the Conscious Leadership Group Diana Chapman (Episode 130). --
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Overthink ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------To be or not to be? That is the question. At the center of Hamlet’s soliloquy is the issue of whether life is worth living. In episode 72 of Overthink, Ellie and David consider this issue with philosopher and existentialism expert Céline Leboeuf. How can we find meaning in our lives when the world seems random and indifferent to our interests? Leboeuf talks about how her personal experience with an existential crisis and her philosophical search for a way out of it led her to consider religious, atheist, and spiritual answers to the question "Why Live?" Ellie and David also consider Camus’ notion of the absurd, and whether life is just a series of blips of suffering with no higher purpose.
Works Discussed
Albert Camus, The Myth of SisyphusWilliam James, “Is Life Worth Living”
Céline Leboeuf, "Why Live? The Three Authors Who Saved Me During an Existential Crisis"
John Jay McDermott “Why Bother: Is Life Worth Living?”
Samuel Scheffer, Death and the AfterlifeLeo Tolstoy, A Confession
Patreon | patreon.com/overthinkpodcast
Website | overthinkpodcast.com
Instagram & Twitter | @overthink_pod
Email | Dearoverthink@gmail.com
YouTube | Overthink podcast
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Moonshots and Mindsets with Peter Diamandis✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, Dakin and Peter discuss tips for new entrepreneurs, how to build a successful company and the power of venture capital for the economy.
You will learn about:
Dakin Sloss is a venture capitalist, founder, entrepreneur, and philanthropist. He is the founder and General Partner of Prime Movers Lab, a VC startup that’s become the world’s leading partner in breakthrough scientific startups.
Learn more about Prime Movers Lab.
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Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Tim Urban is the author of the blog Wait But Why and a new book What’s Our Problem?: A Self-Help Book for Societies. Please support this podcast by checking out our sponsors: – House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit – Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil EPISODE LINKS: Tim’s new book: https://waitbutwhy.com/whatsourproblem Tim’s Twitter: https://twitter.com/waitbutwhy Tim’s Website: https://waitbutwhy.com Tim’s Instagram: https://instagram.com/timurban Tim’s TED talk: https://www.youtube.com/watch?v=Rk5C149J9C0 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes:
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain the biology of breathing (respiration), how it delivers oxygen and carbon dioxide to the cells and tissues of the body and how is best to breathe—nose versus mouth, fast versus slow, deliberately versus reflexively, etc., depending on your health and performance needs. I discuss the positive benefits of breathing properly for mood, to reduce psychological and physiological stress, to halt sleep apnea, and improve facial aesthetics and immune system function. I also compare what is known about the effects and effectiveness of different breathing techniques, including physiological sighs, box breathing and cyclic hyperventilation, “Wim Hof Method,” Prānāyāma yogic breathing and more. I also describe how to breath to optimize learning, memory and reaction time and I explain breathing at high altitudes, why “overbreathing” is bad, and how to breathe specifically to relieve cramps and hiccups. Breathwork practices are zero-cost and require minimal time yet provide a unique and powerful avenue to improve overall quality of life that is grounded in clear physiology. Anyone interesting in improving their mental and physical health or performance in any endeavor ought to benefit from the information and tools in this episode.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanHVMN: https://hvmn.com/hubermanHelix Sleep: https://helixsleep.com/hubermanWHOOP: https://join.whoop.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Breathing(00:05:41) Sponsors: HVMN, Helix Sleep, WHOOP(00:09:36) Respiration, Oxygen & Carbon Dioxide(00:18:18) Breathing Mechanics(00:30:08) AG1 (Athletic Greens)(00:31:23) Chemistry of Breathing, Hyperventilation(00:40:35) High Altitudes, Oxygen & Breathing(00:47:16) Tool: Sleep Apnea, Nasal Breathing(00:51:50) Brain Centers & Breathing Rhythm(00:57:23) Brain, Hyperventilation & “Over-breathing”(01:03:53) What is Healthy Breathing?(01:08:26) InsideTracker(01:09:44) Tool: Train Healthy Breathing, Carbon Dioxide Tolerance Test & Box Breathing(01:22:39) Tool: Breathwork & Stress Reduction; Cyclic Sighing(01:33:56) Tool: Physiological Sighing & Exercise Side Cramp(01:39:16) Breathing & Heart Rate Variability(01:46:21) Tool: How to Stop Hiccups(01:51:17) Tool: Stress Management & Cyclic Hyperventilation, “Wim Hof Method”(01:57:11) Deliberate Cold Exposure & Breathing(01:59:54) Tool: Inhales & Learning; Exhales & Movement(02:09:15) Mouth vs. Nasal Breathing, Aesthetics(02:16:19) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode 5 of a 6-part special series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton, he explains how to optimize post-training recovery and how to avoid overtraining in order to better achieve your fitness and exercise goals. He explains the cellular mechanisms of muscle soreness and pain, why adequate recovery is essential for all physical adaptations, and how to enhance recovery using breathwork, thermal, movement, and pressure-based techniques. He describes how overtraining impedes exercise progress and how to assess if you are overreaching or overtraining, by using specific biomarkers and indicators. Like other performance metrics, recovery is a skill that can and should be trained, and that can be learned. This episode provides an actionable toolkit for how to monitor and improve your exercise recovery abilities, which will improve your overall mental and physical health.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanEight Sleep: https://eightsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Recovery(00:04:17) Exercise & Delayed Muscle Soreness, Pain(00:11:35) Muscle Spindles, Reduce Soreness(00:18:56) Exercise, Homeostasis & Hormesis; Blood Test & Fitness Level(00:30:20) Recovery Timescales, Adaptation & Optimization(00:35:10) Adaptation & Biomarkers Levels(00:40:36) 4 Recovery Levels, Enhance Recovery(00:47:28) AG1 (Athletic Greens)(00:48:19) Overreaching vs. Overtraining(00:52:53) Tool: Acute Overload & Recovery, Breathwork(01:03:39) Tool: Alleviate Acute Soreness, Compression Clothing(01:08:27) Tool: Acute Soreness, Massage, Temperature(01:14:21) Cold & Heat Contrast, Cold Shower vs. Immersion, Sauna & Fertility(01:20:44) InsideTracker(01:21:46) Combine Recovery Techniques(01:24:34) Monitoring for Overreaching & Overtraining(01:31:33) Overreaching/Overtraining, Performance & Physiology, Sleep(01:45:41) Overreaching/Overtraining, Biomarkers, Cortisol(01:50:45) Cortisol, Daily Levels & Performance; Rhodiola Supplementation(02:01:25) Carbohydrates, Cortisol & Sleep(02:05:05) Tool: Stress Biomarkers, Heart Rate Variability (HRV)(02:15:07) Tool: “Acute State Shifters”, Stimulants, Dopamine Stacking, Phones(02:25:04) Mirrors & Resistance Training(02:29:01) Tool: “Chronic State Shifters”(02:32:43) Training Recovery & Resilience; Bowling Alley Analogy(02:39:45) Trigger Adaptations & Stress Recovery (02:42:41) Tool: Measure Recovery; Blood Biomarkers(02:50:06) Libido & Sex Hormones, Supplementation Caution(03:00:08) Tools: No-/Low-Cost Recovery Measurements(03:03:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Founders✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------What I learned from rereading Hard Drive: Bill Gates and the Making of the Microsoft Empire by James Wallace and Jim Erickson.
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[4:00] Gates read the encyclopedia from beginning to end when he was only seven or eight years old.
[4:00] Gates had an obsessive personality and a compulsive need to be the best.
[5:00] Everything Bill did, he did to the max. What he did always went well, well beyond everyone else.
[6:00] You want to maneuver yourself into doing something in which you have an intense interest. — Poor Charlie's Almanack: The Wit and Wisdom of Charles T. Munger.
[7:00] Gates devoured everything he could get his hands on concerning computers and how to communicate with them, often teaching himself as he went.
[9:00] A young man with no money and tons of enthusiasm. — The Dream of Solomeo: My Life and the Idea of Humanistic Capitalism by Brunello Cucinelli. (Founders #289)
[10:00] He consumed biographies to understand how the great figures of history thought.
[11:00] The idea that some people were super successful was interesting. What did they know? What did they do? What drove those kinds of successes?
[12:00] Idea Man: A Memoir by the Cofounder of Microsoft by Paul Allen. (Founders #44)
[13:00] “I’m going to make my first million by the time I'm 25.” It was not said as a boast, or even a prediction. He talked about the future as if his success was predestined.
[15:00] Gates and Allen were convinced the computer industry was about to reach critical mass, and when it exploded it would usher in a technological revolution of astounding magnitude. They were on the threshold of one of those moments when history held its breath... and jumped, as it had done with the development of the car and the airplane. They could either lead the revolution or be swept along by it.
[17:00] Bill had a monomaniacal quality. He would focus on something and really stick with it. He had a determination to master whatever it was he was doing. Bill was deciding where he was going to put his energy and to hell with what anyone else thought.
[18:00] Don’t do anything that someone else can do. — Edwin Land
[21:00] You've got to remember that in those days, the idea that you could own a computer, your own computer, was about as wild as the idea today of owning your own nuclear submarine. It was beyond comprehension.
[23:00] There would be no unnecessary overhead or extravagant spending habits with Microsoft.
[25:00] “Pertec kept telling me I was being unreasonable and they could deal with this guy [Gates]. It was like Roosevelt telling Churchill that he could deal with Stalin.
[27:00] Four years in and Microsoft had only 11 employees.
[28:00] Gates sustained Microsoft through tireless salesmanship. For several years he alone made the cold calls and haggled, cajoled, browbeat, and harangued the hardware makers of the emerging personal computer industry, convincing them to buy Microsoft's services and products. He was the best kind of salesman there is: he knew the product, and he believed in it. Moreover, he approached every client with the zealotry of a true believer.
[29:00] When we got up to 30 employees, it was still just me, a secretary, and 28 programmers. I wrote all the checks, answered the mail, took the phone calls.
[31:00] This might be Bill’s most important decision ever: IBM had talked to Gates about a fixed price for an unlimited number of copies of the software Microsoft licensed to IBM. The longer Gates thought about this proposal the more he became convinced it was bad business. Gates had decided to insist on a royalty arrangement with IBM.
[34:00] You have to be uncompromised in your level of commitment to whatever you are doing, or it can disappear as fast as it appeared.
Look around, just about any person or entity achieving at a high level has the same focus. The morning after Tiger Woods rallied to beat Phil Mickelson at the Ford Championship in 2005, he was in the gym by 6:30 to work out. No lights. No cameras. No glitz or glamour. Uncompromised.
— Driven From Within by Michael Jordan and Mark Vancil. (Founders #213)
[36:00] Overdrive: Bill Gates and the Race to Control Cyberspace by James Wallace. (Founders #174)
[42:00] You can drive great people by making the speed of decision making really slow. Why would great people stay in an organization where they can't get things done? They look around after a while, and they're, like, "Look, I love the mission, but I can't get my job done because our speed of decision making is too slow."
—Invent and Wander: The Collected Writings of Jeff Bezos (Founders #155)
[43:00] Alexander the Great: The Brief Life and Towering Exploits of History's Greatest Conqueror--As Told By His Original Biographers by Arrian, Plutarch, and Quintus Curtius Rufus. (Founders #232)
[44:00] Gates was intolerant of distractions.
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Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Richard Shotton is a behavioural scientist, Founder of Astroten and an author.
This might not be news to you, but the human brain isn't designed to be rational. There are cheat codes to get the brain to believe strange things, do strange things and change in ways you might not anticipate. Richard has one of the best insights into this world of mental models, psychology, consumer behaviour, principles for advertising and social change.
Expect to learn the marketing secret about behaviour change that everyone forgets about, how to make habit formation absolutely seamless, why IKEA is so successful even though they don't make your furniture, a hack that any advertising campaign can use to make it stick in people's minds, how to fix the problem of choice paralysis and much more...
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Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- View the Show Notes Page for This Episode
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Anthony Hipolito is a sheriff’s deputy in Hays County, Texas with over 24 years of experience in law enforcement. In this episode, Anthony discusses his work to spread awareness about illicit fentanyl use and the drastic increase in accidental overdoses, especially in young people. Anthony explains the deadly nature of fentanyl, including how many counterfeit drugs are now being laced with deadly doses of fentanyl. He breaks down how fentanyl is being brought to the US and how younger and younger kids are being targeted. Additionally, Anthony discusses his goal of spreading awareness to our communities and provides important advice for what parents can do.
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The Network State Podcast✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Tobi Lütke (Shopify Founder & CEO), Kaz Nejatian (Shopify COO), and Balaji review how Shopify rose from tiny startup to $180B+ global economy, with an annual GMV on par with the GDP of New Zealand. In the process they touch on Hayek, the Hanseatic League, merchant cavemen, the history of the corporation, and the optimal level of platform decentralization.
OUTLINE
00:00 - Introduction
02:39 - Shopify has the scale of a small country
08:49 - Lifestyle businesses take up your whole life
20:52 - SMBs can be harder than startups
27:13 - Shopify could invest in its merchants
32:23 - Shopify's economy is on par with Greece or New Zealand
38:40 - Money, time, risk, attention
39:55 - Is all retail a form of arbitrage?
47:14 - The history of the corporation informs the development of smart contracts
56:57 - Founders start as lead engineer, end up as chief psychiatrist
1:00:27 - Shopify is not just technology but community
1:06:26 - The concept of computational context
1:14:34 - Shopify as a dashboard for the global economy
1:22:48 - Atoms are so much more complex than bits
1:28:41 - Balancing centralized vs decentralized at Shopify
1:43:26 - If they could start a new country, what would Tobi and Kaz build?
2:03:28 - Kaz on working at Shopify
2:04:31 - Tobi's parting thoughts
LINKS
1) 100 true fans: kk.org/thetechnium/1000-true-fans/
2) Gobekli Tepe: smithsonianmag.com/history/gobekli-tepe-the-worlds-first-temple-83613665
3) Shopify active merchant: github.com/activemerchant/active_merchant
4) Fall of Civilizations: youtube.com/@FallofCivilizations
5) Founding vs Inheriting: thenetworkstate.com/founding-vs-inheriting
6) Shopify careers: shopify.com/careers
VIDEO
YouTube: youtube.com/@thenetworkstatepodcast
CREDITS
Editing: twitter.com/DholakiaJaydeep
Images: twitter.com/DholakiaJaydeep
SOCIAL
twitter.com/tobi
twitter.com/CanadaKaz
twitter.com/balajis
thenetworkstate.com
Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Psychologist Adam Mastroianni says peer review has failed. Papers with major errors make it through the process. The ones without errors often fail to replicate. One approach to improve the process is better incentives. But Mastroianni argues that peer review isn't fixable. It's a failed experiment. Listen as he makes the case to EconTalk host Russ Roberts for a new approach to science and academic research.
Honestly with Bari Weiss ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------For many parents, the last few years have been eye-opening, as they saw the education system in America crumble under the weight of the pandemic. School closures that went on far too long, ineffective zoom school for kids as young as kindergarten, and other stringent policies that we’re still just beginning to understand the devastating effects of. But like many things during the pandemic, COVID didn’t necessarily cause these structural breakdowns as much as it exposed just how broken the system was to begin with. Nowhere is that more clear than in our episode today about why 65% of American fourth grade kids can barely read. And about how during the pandemic, parents, for the first time, came face to face with just how bad and ineffective the reading instruction in their kids’ classrooms is and started asking questions about why.That is the subject of Emily Hanford's new podcast from American Public Media, Sold a Story, where she investigates the influential education authors who have promoted a flawed idea and a failed method for teaching reading to American kids. It’s an expose of how educators across the country came to believe in something that isn’t true and are now reckoning with the consequences – children harmed, money wasted, an education system upended. Today, guest host Katie Herzog talks to Emily about her groundbreaking reporting and what we can do to make things right. Learn more about your ad choices. Visit megaphone.fm/adchoices
Wise Traditions: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------The bottles of yellow oil on the supermarket shelves are labeled heart-healthy but they are in actuality damaging for our health (and the heart). These seed oils are unstable fats extruded from seeds that are not meant for human consumption. They are deodorized and colorized to make them look and taste appealing, but they are rancid and difficult to digest. They can (and do) lead to a host of health conditions from obesity, to cancer, to diabetes, to premature aging.
Sally Fallon Morell, president of the Weston A. Price Foundation, describes the issues with these oils: canola, safflower, sunflower, soy and more. Sally explains how to spot the seed oils in our foods and how to swap them out of the diet.
Visit Sally's website for her blog: nourishingtraditions.com
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In episode 4 of a 6-part series, Andy Galpin, PhD, explains how to design an effective training program for fitness, health and longevity through a 10-step approach. He covers goal setting, exercise selection, balancing, recovery periods and real-world challenges. He provides a year-long training example that considers sleep, sunlight and social connection. The program is modifiable for personal fitness goals and experience.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanEight Sleep: https://eightsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Optimal Fitness Programming(00:07:19) Sponsors: Momentous, Eight Sleep(00:09:53) #1: Plan Fitness Goals, S.M.A.R.T. Goals(00:19:52) Intermediate Goals, Dopamine, Identify Your “Defender”, Goal Timing(00:26:25) Multiple Goals, Synergistic Goals, Interference Effects(00:36:13) AG1 (Athletic Greens)(00:37:060 Physical Goal “Bins”, Specificity (00:48:02) Tool: #2: Identify Your “Defender”, Quadrant System, “Drop Everything and…”(01:04:330 InsideTracker(01:05:35) #3: Goal Timeframe & Life Events; #4: Weekly Training Frequency(01:10:33) #5: Exercise Selection, Progression (01:18:200 #6: Exercise Order, Identify Friction(01:29:20) Exercise Timing & Sleep, Down Regulation, Caffeine(01:36:24) #7: Intensity, #8: Volume, Progressive Overload, “Deloading”(01:43:59) #9: Rest Intervals, #10: “Chaos Management”(01:49:06) Fitness, Health & Longevity Goals, Proprioception & Non-Structured Exercise(01:53:41) Tool: Year-Long Program Example for Overall Fitness(02:07:58) Tool: Overall Fitness Template by Quarter, Matching Goals & Seasons(02:25:49) Training & Life Challenges: Sleep, Illness (02:32:10) Tool: Program Flexibility, 3-Day Weekly Training Program(02:37:12) Physical Activity vs. Exercise(02:40:12) Tool:4-Day Weekly Training Program, Muscular Endurance(02:51:15) Tool: 5/6-Day Weekly Training Program, Recovery(02:54:06) Program Modification, Balancing Joy(03:04:47) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest this episode is Gina Poe, PhD, a professor in the department of integrative biology & physiology at the University of California, Los Angeles (UCLA). We discuss her research exploring how sleep impacts learning, memory, hormones and emotions. She discusses tools to enhance your quality of sleep, increase deep sleep, rapid eye movement sleep and growth hormone release-- a key hormone for health, immune function and vitality. Dr. Poe explains how a specific brain area, the locus coeruleus, facilitates the processing of emotions, helps relieve traumas and how to maximize locus coeruleus function. She also explains sleep’s vital role in opiate addiction recovery and how anyone can determine their optimal sleep timing and duration. This episode is rich with basic science information and zero-cost tools to enhance quality and effectiveness of sleep for sake of mental health, physical health and performance.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanHelix Sleep: https://helixsleep.com/hubermanEight Sleep: https://eightsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dr. Gina Poe(00:02:52) LMNT, Helix Sleep, Eight Sleep, Momentous(00:06:58) Sleep Phases, Perfect Night’s Sleep(00:10:32) Can You Oversleep?(00:14:50) Sleep Cycles, Sleep Spindles, “Falling” Asleep, Dreams & Memories(00:19:01) Tool: Growth Hormone Release & Sleep(00:22:05) Adolescence; Early Sleep, Alcohol & Sleep Spindles(00:24:55) Middle Sleep States & REM, Schema, Waking at Night(00:30:33) Deep Sleep, Dreams & Senses(00:33:22) AG1 (Athletic Greens)(00:34:37) Later Sleep, Paralysis, Sleepwalking, Sleep Talking(00:36:47) Alarm Clock & Grogginess; Sleep Trackers, Brain & Sleep(00:43:19) Early Slow Wave Sleep & “Washout”, Normal Sleep Cycle & Night Owls(00:54:30) Locus Coeruleus, Learning & REM Sleep(01:01:46) Post-Traumatic Stress Disorder (PTSD), Locus Coeruleus & Sleep(01:06:13) InsideTracker(01:07:31) Locus Coeruleus, Trauma & Sleep, Antidepressants, Norepinephrine(01:12:29) Locus Coeruleus, Bedtime & Novelty, Estrogen & Trauma(01:16:22)Sex Differences & Sleep(01:19:12) Tool: Non-Sleep Deep Rest (NSDR), Insomnia, Meditation, Prayer(01:27:42) Sleep Spindles, Learning & Creativity, P Waves & Dreaming(01:34:51) Lucid Dreams, Reoccurring Dreams, Trauma(01:44:11) Trauma Recovery, Locus Coeruleus & Norepinephrine, REM Sleep (01:52:15) Opiates, Addiction, Relapse & Sleep(02:02:45) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Neural Network Newsletter, Social MediaTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I discuss the causes and treatments of different types of headaches, including tension headaches, migraines, sinus and cluster headaches, as well as menstrual and other hormone-based headaches. I describe how to distinguish between the different headache types and how to select the right treatment, including prescription-based and non-prescription-based treatments, behavioral and nutrition-based approaches. I also explain the evidence and mechanisms supporting the use of omega-3 fatty acids, high dose creatine, peppermint oil, turmeric, acupuncture and more. Additionally, I touch on traumatic brain injury, the causes of photophobia, aura, and the link between spicy foods and thunderclap headaches. By the end of this episode, listeners and viewers will have a comprehensive understanding of headaches, their types and the best way to prevent and stop them.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanThesis: https://takethesis.com/hubermanLMNT: https://drinklmnt.com/hubermanMaui Nui Venison: https://mauinuivenison.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanHuberman Lab Premiumhttps://hubermanlab.com/premiumTimestamps(00:00:00) Headache(00:03:51) Sponsors: Thesis, LMNT, Maui Nui, Momentous(00:07:47) Headache Sources: Muscle Tension; Blood Flow & Meninges(00:14:06) Headache Sources: Neurons; Inflammation & Sinus Headache (00:23:21) 3 Neuron Types, Pain, Tension Headaches(00:31:05) Tension Headaches(00:33:25) AG1 (Athletic Greens)(00:34:29) Migraine Headaches, Aura, Photophobia (00:43:10) Cluster Headaches(00:47:47) Hormone-Based Headaches, Menstrual Cycle & Menopause(00:53:38) Traumatic Brain Injury (TBI) & Headache, Baseline Health(01:02:08) Tool: Headache Treatment, Creatine Monohydrate & TBI(01:12:22) InsideTracker(01:13:55) Headache Treatment, Omega-3 & Omega-6 Fatty Acids (Linolic Acid)(01:22:14) Tool: Omega-3 Supplementation, Omega-6 Fatty Acids & Inflammation(01:28:11) Hormone Headache Treatment & Omega-3s(01:31:24) Tool: Aura, Photophobia & Offsetting with Red Light (01:44:15) Tool: Tension Headache & Botox Treatment(01:49:43) Tool: Alternative Headache Treatments, Peppermint Oil, Menthol(02:01:35) Tool: Tension Headaches Treatment & Acupuncture(02:05:41) Tool: Migraine & Herbal Treatment, Caffeine Timing(02:13:26) Tool: Migraine Treatments & Curcumin (Turmeric)(02:18:00) Carolina Reaper Pepper & Thunderclap Headache(02:24:21) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Social Media, Momentous, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Doctor's Farmacy with Mark Hyman, MD: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------This episode is brought to you by Rupa Health, InsideTracker, and Pendulum.
Of all the things we do each day, breathing is arguably the most important. While breathing’s most important job is to literally keep us alive, breathing can help in many more ways than just survival, including activating your parasympathetic nervous system, which helps slow your heart rate and lower your blood pressure.
In today’s episode, I talk with James Nestor, Dr. Louis Ignarro, Wim Hof, and Dr. Jim Gordon about using breathing to support your health.
James Nestor is an author and journalist who has written for Scientific American, Outside, The New York Times, and more. His latest book, Breath: The New Science of a Lost Art, was an instant New York Times bestseller. Breath explores how the human species has lost the ability to breathe properly—and how we can get it back.
Dr. Louis Ignarro is a medical research scientist who was awarded the Nobel Prize in Medicine for his breakthrough discovery of nitric oxide and how it positively impacts health and longevity. His groundbreaking research on nitric oxide paved the way for—among other innovations—Viagra. He is an award-winning Distinguished Professor Emeritus of Molecular & Medical Pharmacology at the University of California, Los Angeles, and has his PhD in pharmacology.
Wim Hof, also known as “The Iceman,” holds multiple world records for his feats of endurance and exposure to cold. He is the author of The Wim Hof Method: Activate Your Full Human Potential. The benefits of Wim’s method, now practiced by tens of thousands, have been validated by eight university research studies.
Dr. James Gordon, author of Transforming Trauma: The Path to Hope and Healing, is a Harvard-educated psychiatrist and the founder and CEO of the nonprofit Center for Mind-Body Medicine in Washington, DC. He is a clinical professor at Georgetown Medical School and was chairman (under Presidents Clinton and G.W. Bush) of the White House Commission on Complementary and Alternative Medicine Policy.
This episode is brought to you by Rupa Health, InsideTracker, and Pendulum.
Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.
Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman.
To receive 20% off your first Pendulum purchase, go to Pendulumlife.com and use code HYMAN.
Full-length episodes of these interviews can be found here:
James Nestor
Dr. Louis Ignarro
Wim Hof
Dr. Jim Gordon
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------This is episode 3 of a 6-part special series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton. He explains protocols to improve the various kinds of physical endurance: muscular endurance, anerobic capacity, maximum aerobic output, and long duration endurance. He also explains how the body uses different energy sources (carbohydrates, proteins, fats) during rest and exercise. He also explains the mechanisms underlying fat loss and how and why exercise accelerates rates of fat loss. We cover the many concepts related to endurance training and fat loss such as metabolic flexibility, breathwork training for exercise performance and recovery, lactate production and regulation, how to improve blood flow to muscles, anaerobic vs. aerobic metabolism, exercise fatigue, low-carbohydrate diets and fat loss, and how to combine different types of workouts to improve overall endurance. This episode in intended for everyone ranging from novice and recreational exercisers to elite endurance athletes. Anyone wishing to improve their physical health and performance stands to benefit from the information.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLevels: https://levels.link/hubermanLMNT: https://drinklmnt.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Endurance: Benefits, Mechanics & Breathing (00:07:30) Tool: “Exercise Snacks”(00:14:21) Momentous, Levels, LMNT(00:18:01) Endurance Categories(00:22:16) Fat Loss & Respiration; Carbon Cycles & Storage, Metabolism(00:33:08) Exhalation Rates, Exercise & Fat Loss; Calories(00:41:47) Cardiovascular Adaptations, Cardiac Output & Maximum Heart Rate(00:47:03) AG1 (Athletic Greens)(00:47:55) Excess Post-Exercise Consumption (EPOC); Exercise Intensity & Fat vs. Carbohydrate Energy Utilization(00:59:35) Tool: Training for Fat Loss, Carbohydrate Stores, Liver Glycogen & Fatigue(01:08:01) Metabolic Flexibility, Carbohydrates & Fat; Exercise & Flexible Fuel Utilization (01:16:07) Muscle & Basal Metabolic Rate(01:19:40) InsideTracker(01:20:43) Assessing Metabolic Flexibility, Blood Glucose, Carbohydrates(01:27:48) Caffeine, High-Carbohydrate Meals & Timing, Managing Daily Energy (01:36:42) Cellular Energy (ATP) Production from Carbs; Lactate; Anerobic, Aerobic(01:50:45) Lactate, Energy Production Buffer(01:53:14) Fuel Sources & Exercise; Mitochondria, Oxygen Availability & Lactate(02:02:50) Lactate for Exercise & Cognitive Performance(02:04:33) Energy Production, Waste Management & Endurance Exercise; Insulin(02:12:49) Protein & Fat Utilization for Energy; Exercise & Fat Loss(02:21:20) Protein as Fuel Source, Fire Analogy (02:26:39) Low-Carbohydrate Diet & Performance(02:29:40) Muscular Endurance: Fuel Sources, Training & Capillarization(02:37:30) Tool: Muscular Endurance & Modifiable Variables; Examples(02:45:07) Anerobic Capacity: Fuel Sources, Training & Oxygen Utilization (02:49:23) Tool: Cardiac Output, Heart Rate Zones & Breathing “Gear System”(02:58:10) Tool: Anerobic Capacity & Modifiable Variables; Examples, Nasal Recovery(03:11:45) Tool: “Sugarcane” Endurance Protocol (03:14:02) Anerobic Capacity, Training Progression (03:16:40) Tool: Maximum Aerobic Output, Training & Modifiable Variables(03:21:58) Tool: Long Duration Endurance, Training, Circuits(03:25:13) Long Duration Endurance, Capillarization, Fatigue & Breathwork, Technique(03:29:10) Weekly Combination Training, Metabolic Flexibility & Longevity(03:37:23) Tool: Mixed Endurance Training, Half Marathon Example(03:47:33) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest is Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and clinical assistant professor of integrative medicine & nutritional sciences at Thomas Jefferson University. Dr. Gottfried specializes in hormone health, vitality and longevity using precision/personalized approaches. We discuss female hormone health, puberty, perimenopause, and menopause, hormone testing, the microbiome, stress related hormone challenges, their causes, and various treatments. We also discuss fertility, birth control and tools for improving microbiome health, treating PCOS, insulin management, and the best nutrition, supplementation, and exercise programs for women. While the episode focuses mainly on female hormones, males will also benefit from our discussion because it includes actionable tools suggested for managing stress, bolstering the gut microbiome, and immunity—all of which stand to improve overall health, vitality and longevity in males and females.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanROKA: https://roka.com/hubermanThesis: https://takethesis.com/hubermanLMNT: https://drinklmnt.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Dr. Sara Gottfried(00:03:51) ROKA, Thesis, LMNT, Momentous(00:07:50) Women, Family History, Heredity & Environment(00:11:00) Puberty, Stress, Menstrual Cycles, Intrauterine Devices (IUDs)(00:17:26) Tool: Sex Hormones, Microbiome, Estrobolome & Disease; Biomarker Testing(00:25:11) Nutritional Testing; Vegetables, Microbiome & Disease(00:31:13) AG1 (Athletic Greens)(00:32:22) Microbiome, Prebiotics & Probiotics, Inflammation(00:36:08) Microbiome Testing, Magnesium, Constipation & Thyroid(00:42:25) Female Colonoscopy; Network Effect & Modern Medicine, Stress Factors(00:45:13) Constipation, Stress & Trauma, Autonomic Balance(00:55:35) Constipation Relief, Stress, Breathwork & Meditation(01:02:58) Systemic & Societal Stress Unique to Females(01:08:19) InsideTracker(01:09:23) Testing & Future Behavior(01:11:55) Polycystic Ovary Syndrome (PCOS) & Cardiometabolic Disease; Stress (01:22:57) PCOS, Insulin, Glucose Monitoring and Management; Data Access(01:29:48) Behaviors for Vitality; Exercise & Body Phenotype; Cortisol(01:36:40) Cortisol Supplements: Ashwagandha, Rhodiola, Fish Oil, Phosphatidylserine(01:42:36) Cortisol, Anxiety & Immune System; Adrenal Function, Resilience(01:48:07) Tool: Omega-3 Fatty Acids, Inflammation, Specialized Pro-Resolving Mediators(01:54:20) Oral Contraceptives, Benefits & Risks; Ovarian Cancer; Testosterone(02:06:50) Fertility, Follicular & Anti-Mullerian Hormone (AMH) Assessments(02:10:29) Menopause & Hormone Replacement Therapy; Women’s Health Initiative(02:15:30) Perimenopause, Cerebral Hypometabolism, Metabolism & Estrogen(02:21:49) Intermittent Fasting, Ketogenic Diet, Metabolic Flexibility (02:23:29) Stool Testing(02:25:32) Coronary Artery Calcium (CAC) Test, ACE Score & Disease (02:31:56) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Neural Network Newsletter, MomentousTitle Card Photo Credit: Mike BlabacDisclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode 2 of a 6-part special series, Dr Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton and world expert on exercise science, explains optimal protocols for increasing strength and causing hypertrophy (muscle growth), as well as for increasing speed and power. He explains the training principles and underlying mechanisms for reaching these goals. Our conversation covers a breadth of training topics, including selecting the number of repetitions, sets, inter-set and inter-workout rest periods, warm-ups, exercise cadence, breathing, stretching, recovery, training frequency, overcoming plateaus, nutrition, and he gives specific examples of exercises for power, strength, and hypertrophy.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanEight Sleep: https://eightsleep.com/hubermanLevels: https://levels.link/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Benefits of Strength & Hypertrophy Training, Aging(00:10:52) Strength & Hypertrophy Training, Aesthetics (00:14:02) Momentous, Eight Sleep, Levels(00:17:48) Strength vs. Hypertrophy Training: Adaptations(00:22:42) Ligaments, Tendons & Resistance Training(00:28:05) Bone Strength & Resistance Training, Age, Women(00:32:38) Strength Training & Major Adaptations(00:41:32) AG1 (Athletic Greens) (00:42:25) Hypertrophy Training & Major Adaptations; Protein Synthesis(00:45:56) Endurance vs. Strength Training & Cell Signaling, Protein Synthesis(00:52:26) Muscle Hypertrophy, Sarcoplasmic Hypertrophy(00:56:37) Muscle Physiology & Plasticity, Muscle “Memory”(01:04:00) Non-Negotiables & Modifiable Variables of Exercise Training(01:11:51) InsideTracker(01:12:53) Tool: Speed & Power Training, “3 to 5” Approach, Periodization, Planning (01:22:02) Warming Up & Training, Dynamic Movements(01:30:55) Strength vs. Hypertrophy Repetition Cadence, Triphasic Training(01:44:03) Tool: Breathing & Training, Valsalva Technique(01:53:22) Tool: Training Auto-Regulation, Specificity vs. Variation, Prilepin's Chart(02:02:35) Training to Failure, Exercise Selection & Recovery, Standardization(02:13:45) Tool: Power vs. Strength Training & Modifiable Variables; Supersets (02:24:22) Sets & Rest Periods; Stretching(02:28:48) Tools: Power Training & Modifiable Variables; Examples(02:30:16) Tools: Strength Training & Modifiable Variables, Cluster Sets, Dynamic Variable Sets(02:40:44) Power & Strength Training Protocols(02:43:37) Intention, Focus & Exercise(02:47:29) Hypertrophy Training Program, Muscle Growth & Signaling (02:55:12) Tools: Hypertrophy Training & Modifiable Variables; Examples(03:03:02) Balanced Muscle Development & Hypertrophy(03:09:04) Tools: Hypertrophy Training & Modifiable Variables; Splits(03:23:08) “Non-Responders” & Exercise Plateaus, Volume(03:27:06) Hypertrophy, Repetition & Rest Ranges, Muscle Failure, “Chaos Management”(03:37:39) Frequency & Workout Duration, Splits(03:44:52) Training Frequency, Infrequent Training, Intermediate Repetition Ranges(03:55:22) Hypertrophy, Muscle Damage & Recovery(04:01:15) Combining Cardiovascular & Hypertrophy Training, Interference Effect(04:06:22) Hypertrophy Training Protocols (04:12:06) Tool: Neck & Rear Deltoid Exercises, Stabilization & Hypertrophy(04:14:42) Hypertrophy: Reps, Sets & Progression, “Hidden” Stressors, Exercises to Avoid(04:21:09) Deliberate Cold Exposure & Hypertrophy vs. Strength(04:26:41) Nutrition, Timing & Strength/Hypertrophy; Creatine(04:38:04) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer
Y Combinator: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Step inside the Group Partner Lounge to hear Y Combinator Group Partners Harj Taggar, Michael Seibel and Brad Flora discuss the many different mistakes founders make when they approach hiring for their startup and how to grow your team the correct way.
Apply to Y Combinator: https://www.ycombinator.com/apply/
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------David Goggins is a retired United States Navy SEAL, ultramarathon runner, triathlete, public speaker and an author.
The ability to overcome challenges in life is one we will all need sooner or later. Make no mistake, discomfort is coming for you whether you're ready or not. Goggins happens to be one of the best individuals on earth at dealing with hard things and after a long time without any podcast appearances, I met him in Vegas to find out what new insights he's uncovered.
Expect to learn what most people get wrong about motivation, Goggins' thoughts on claims that SEAL selection is too hard, what the most painful experience of his life was, the danger of success making you soft, why he ran the MOAB 240 twice with no knee cartilage, why he recorded a mixtape of insults from the internet, how to overcome laziness, what David's entire daily routine looks like and much more...
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A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------At the end of 2022, our team at a16z asked dozens of partners across the firm to spotlight one big idea that startups in their fields could tackle in 2023.
Emerging from this exercise came 40+ builder-worthy pursuits for the year, ranging from entertainment franchise games to precision delivery of medicine to small modular reactors, and of course loads of AI applications.
In our 2-part series, we’ll be covering 12 of these big ideas with the partners that shared them.
Here in part 1, we’ll cover Consumer, Games, and Enterprise, with a little Fintech sprinkled in. Listen in as we chat with Connie Chan, Anne Lee Skates, Jack Soslow, Doug McCracken, Sarah Wang, and Sumeet Singh.
And look out for part 2 dropping soon, covering Fintech, American Dynamism, and Bio & Health!
For the full list of 40+ ideas, check out the full article: https://a16z.com/2022/12/15/big-ideas-in-tech-2023/
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Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I discuss the mechanisms by which human eggs and sperm are generated, the ovulatory/menstrual cycle, the conception process and overall fertility in males and females. I also explain how, regardless of whether you seek to conceive children, optimizing egg and sperm health is directly related to vitality and longevity. I cover the nutrition-based, behavioral, supplement-based and prescription approaches to optimizing egg and sperm health, the ovulatory/menstrual cycle and fertility. In addition, I explain lifestyle choices that greatly assist or harm fertility—several of which are very surprising. I provide science-based protocols for those trying to conceive children. The tools and principles I discuss can also improve overall vitality and longevity in all people, regardless of age. For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanMaui Nui: https://mauinuivenison.com/hubermanEight Sleep: https://eightsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Fertility, Vitality & Longevity(00:04:24) Maui Nui Venison, Eight Sleep, Momentous(00:08:20) Eggs & Sperm, Genes, Fertilization(00:18:28) Puberty: Gonadotropin Releasing Hormone (GnRH), Melatonin & Leptin(00:23:38) Onset Trends of Puberty, Odors Effects(00:31:24) Female Puberty, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH)(00:35:25) AG1 (Athletic Greens)(00:36:34) Ovulatory & Menstrual Cycle(00:40:36) Follicular Phase: Egg Maturation & Ovulation, FSH & Estrogen(00:51:09) Luteal Phase: Progesterone & Estrogen, Menstruation(00:58:14) Ovulation & Libido; Luteal Phase & Malaise; Individual Variability(01:03:14) InsideTracker(01:04:18) Sex Chromosomes, Sperm(01:11:40) Tool: Testicular Temperature & Fertility(01:17:22) Sperm Production, Seminal Fluid, Vasectomy(01:24:07) Sperm Cells, Mitochondria & Motility, Intercourse Frequency & Fertilization(01:28:31) Sperm Production, GnRH, FSH, LH & Testosterone(01:36:21) Ejaculate Quality, Sperm Counts, Fertilization, Ectopic Pregnancy(01:44:14) Tool: Sexual Intercourse Frequency & Fertilization(01:53:24) Tools: Tracking Ovulation, Libido, Lubricants(01:56:42) Fecundability: Egg Quality & Woman’s Age, Cumulative Pregnancy Rate(02:08:17) Miscarriages, Chromosomal Abnormalities(02:11:23) Female Fertility: Age, Follicle Testing & Anti-Mullerian Hormone (AMH) Testing(02:18:51) Male Fertility: Sperm Analysis, Age(02:24:52) Fertility & Hormone Analysis, Age(02:29:07) Fertility Effects of Sleep, Cortisol/Stress, Cannabis/Nicotine & Alcohol(02:42:40) Fertility, Sexually Transmitted Infections (STIs), Viral Infection & Cystic Fibrosis(02:47:42) Tool: Testicular Temperature & Fertility(02:51:26) Tool: Phones & Sperm Quality(02:58:06) Deliberate Cold Exposure & Fertility, Testicular Temperature, Cortisol/Stress(03:05:43) Fertility, Exercise & Mitochondrial Health; Intermittent Fasting(03:14:46) Testosterone Replacement Therapy & Sperm Production; Supplements(03:20:36) Sex Determination in Offspring, In Vitro Fertilization (IVF), Sperm Fractions(03:32:23) Postcoital Female Position & Fertilization, Sperm Quality(03:36:57) Cannabis & Sperm Motility, Libido, Pregnancy(03:42:33) Acupuncture, Fertility & Pregnancy(03:49:25) Fertility Supplements: L-Carnitine & Allicin, Coenzyme Q10(03:56:18) Fertility Supplements: Inositol, Omega 3 Fatty Acids(04:02:50) Supplements for Hormones: Tongkat Ali, Shilajit, Zinc(04:13:02) Fertility & Prescription Medications(04:16:44) Human Reproduction & Fertility(04:20:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterDisclaimerTitle Card Photo Credit: Mike Blabac
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Author, CEO of VUDU Marketing and digital nomad Sam McRoberts returns for his second appearance on Infinite Loops. This week, Sam and Jim discuss Sam’s latest book ‘The Grand Redesign’.
Part science-fiction, part operating manual for upgrading human OS, ‘The Grand Redesign’ touches on a number of recurring Infinite Loops themes, and is available for free online (see ‘Important Links’ section below).
Important Links:
Show Notes:
Books Mentioned:
All-In with Chamath, Jason, Sacks & Friedberg: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------(0:00) Bestie New Year catch-up!
(2:44) Prediction 1: 2023's biggest political winner
(17:25) Prediction 2: 2023's biggest political loser
(21:57) Prediction 3: 2023's biggest business winner
(30:34) Prediction 4: 2023's biggest business loser
(42:03) Prediction 5: 2023's biggest business deal
(52:41) Prediction 6: 2023's most contrarian belief
(1:03:03) Prediction 7: 2023's best-performing asset
(1:07:50) Prediction 8: 2023's worst-performing asset
(1:14:46) Prediction 9: 2023's most anticipated trend
(1:21:40) Prediction 10: 2023's most anticipated media
(1:27:07) Breaking news: OpenAI reportedly in talks to sell existing shares at a ~$29B valuation
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Referenced in the show:
https://www.wsj.com/articles/citadel-posts-record-revenues-for-hedge-fund-securities-operations-11672942665
https://www.reuters.com/world/saudi-arabia-gathers-chinas-xi-with-arab-leaders-new-era-ties-2022-12-09/
https://www.nytimes.com/2023/01/03/business/europe-natural-gas-prices.html
https://www.nytimes.com/2023/01/04/technology/salesforce-layoffs.html
https://www.wsj.com/articles/amazon-to-lay-off-over-17-000-workers-more-than-first-planned-11672874304
https://twitter.com/DavidSacks/status/1598076726671642624
https://www.nytimes.com/2022/12/30/world/asia/xi-putin-china-russia.html
https://twitter.com/JenniferJJacobs/status/1611052287954149377
https://www.bloomberg.com/news/articles/2023-01-03/blackstone-s-breit-gets-4-billion-from-university-of-california
https://www.nbcnews.com/politics/congress/gop-rebels-block-kevin-mccarthy-defiance-trump-rcna64280
https://www.wsj.com/articles/chatgpt-creator-openai-is-in-talks-for-tender-offer-that-would-value-it-at-29-billion-11672949279
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest is Rick Rubin, one of the most renowned music producers of all time, known for his work with a wide range of artists, including Run DMC, Public Enemy, Beastie Boys, Red Hot Chili Peppers, JayZ, Adele, Johnny Cash, LL Cool J, Slayer, Neil Young, Kanye West, Tom Petty, and many more. He is also the author of a new book, "The Creative Act: A Way of Being," which explores the creative process and how to access creativity. We discuss topics such as finding inspiration, the role of feelings as guideposts, learning from observing nature, balancing self-doubt and anxiety, and adopting new perspectives to channel the creative process. Rick also shares his thoughts on using deadlines, eliminating distractions, and how our experiences and emotions influence the creative process. Additionally, we discuss his love for professional wrestling. Our conversation can be applied to any activity or profession to access creativity.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanMaui Nui: https://mauinuivenison.com/hubermanThesis: https://takethesis.com/hubermanWHOOP: https://join.whoop.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Rick Rubin(00:04:08) Maui Nui Venison, Thesis, WHOOP, Momentous(00:08:23) Creativity & Ideas, Cloud Analogy (00:12:26) Language & Creativity; Kids(00:17:36) Feelings & Creative Ideas(00:22:01) Rules, Choice & Art; Personal Taste & Other’s Opinions (00:30:20) Changing Perspective & Creativity(00:33:55) AG1 (Athletic Greens)(00:35:04) Scientific Knowledge; Opinions & Art(00:41:27) Finishing Projects; The Source & Nature(00:47:40) Perception Filters, Contrast & Novelty(00:58:42) Music & Identity, Evolving Tastes(01:03:03) InsideTracker(01:04:14) Focus, Disengaging & Subconscious; Anxiety (01:13:22) Collaboration, Art & Rigorous Work(01:18:26) Process & “Cloud”; Perception & Storytelling(01:29:13) Limited Resolution, Considering the Inverse(01:35:38) Wrestling, Energy & Reality; Dopamine (01:49:43) Wrestling, Style & Performance(01:52:40) Resetting Energy & Nature; Nostalgia(02:01:56) Sleep, Waking Up & Sunlight, Capturing Ideas(02:08:16) Creative Work Phases; Structure & Deadlines(02:15:32) Self-Doubt & Performance(02:19:13) Predictability & Surprise, Authenticity (02:25:02) Past Experiences, Other’s Opinions (02:29:42) Public Opinion & Science: Light, Acupuncture & Nutrition (02:39:44) “Look for Clues”, Belief Effects (02:46:25) Attention, Emotion & Art(02:48:07) Mantra Meditation, Awareness Meditation (02:57:33) Rick Rubin Questions, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterDisclaimerTitle Card Photo Credit: Mike Blabac
A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------with @robertiger @cdixon @smc90
A wide-ranging conversation with Bob Iger on the interplay between technology, content, and distribution; as well as Bob’s journey -- and that of various creators! -- especially as the industry evolved from TV and cable to the advent of the internet/ web 1.0 to 2.0 to briefly touching on web3 and other emerging technologies. As well as topics top of mind for all company and community builders: from build vs. buy and the innovator's dilemma, to managing creativity, decentralization, remote work, and much more.
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Feel Better, Live More with Dr Rangan Chatterjee✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------I believe that conversation matters; that long form nuanced conversation is what we need now more than ever, to make the world a better place. And for me, part of that means exposing ourselves to new ideas, new concepts and new ways of thinking that we may previously have not been exposed to. This week’s guest on my Feel Better Live More Podcast is someone who fits that bill perfectly.
Dr Zach Bush is a medical doctor and founder of the non-profit Farmer’s Footprint, created to find root cause solutions for human and ecological health. His passion for education reaches across many disciplines, including genomics, the immune system, and gut brain health.
Zach spent many years as a conventional doctor, specialising in internal medicine, endocrinology and hospice care. Disillusioned with the state of Western medicine, he began taking an integrative approach, studying the body’s microbiomes in relation to health, disease and food systems. Today though, Zach describes his life and work as ‘dedicated to the health of humanity and the planet we call home’.
In this conversation, Zach makes the case for a revolution in how we understand ourselves, our fellow humans, our healthcare and farming systems – and how we save the world. This episode is a rollercoaster ride through biology, physics, philosophy, economics and environmentalism – all sprinkled with a good dose of inspiration.
Zach and I share the view that healthcare needs radical change. It can no longer be about doctors telling patients what’s wrong and prescribing drugs and treatments that don’t look at the whole person.
We discuss how traits of ego, individualism and competition aren’t really human at all. And Zach explains how the realisation that all living beings are energetically connected and interdependent is the key to transformation – we cannot thrive as one species if we wipe out others.
We also talk about saving our soil and our food systems through regenerative agriculture, and encouraging individuals, farmers and big industry to work together to save the internal and external ecosystems that none of us could live without.
Yes, these are big topics. But ultimately, Zach’s message is one of hope. He’s not afraid to put forward big solutions, and they’re all made up of steps each one of us can start taking from today.
This is a really special conversation. It's honest, evocative and at times, provocative. I hope you enjoy listening.
Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.
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DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 405: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about what happens when Shaan leaves the house and meets up with other founders, the power of storytelling, the things you learn when you sell a company and how to hire a researcher.Want to see more MFM? Subscribe to the MFM YouTube channel here.-----Links: Alpha Paw Genius Litter Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(04:20) - Shaan leaves the house and meets cool people(13:15) - When Ramon pretended to be an electrician(18:30) - Power of storytelling(21:25) - Age and perception(28:25) - Frame break(30:10) - Things you learn when you sell a company(46:05) - How to hire a researcher-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------MrBeast is a legendary YouTube creator. Please support this podcast by checking out our sponsors: – House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order – Eight Sleep: https://www.eightsleep.com/lex to get special savings – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: MrBeast Main Channel: https://youtube.com/@MrBeast MrBeast Reacts: https://youtube.com/@BeastReacts MrBeast Gaming: https://youtube.com/@MrBeastGaming MrBeast Philanthropy: https://youtube.com/@BeastPhilanthropy MrBeast’s TikTok: https://tiktok.com/@mrbeast MrBeast’s Twitter: https://twitter.com/MrBeast MrBeast’s Instagram: https://instagram.com/mrbeast Feastable’s Website: https://feastables.com MrBeast Burger’s Website: https://mrbeastburger.com MrBeast’s Merch: https://shopmrbeast.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Welcome to a sneak peek of the third Ask Me Anything (AMA) episode, part of Huberman Lab Premium.The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.Subscribe to Huberman Lab Premium at https://hubermanlab.com/premiumTimestamps(00:00:00) Introduction00:00:00 Introduction00:01:27 Adaptogens [Justine Bevilacqua]00:29:42 Huberman Lab PremiumIn the full 1.5 hour+ AMA episode, we discuss:Caloric restriction in fertile womenCognitive load limitsPotential risks of Bluetooth, Wi-Fi, EMFsCreatine and agingTitle Card Photo Credit: Mike BlabacDisclaimer
Honestly with Bari Weiss ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------When my wife Nellie was pregnant last year, we became obsessed with Economist Emily Oster’s book, Expecting Better: Why the Conventional Pregnancy Wisdom Is Wrong–and What You Really Need to Know. Amidst a barrage of conflicting and confusing pregnancy advice, Oster laid out the data on everything we needed to know. Despite what doctors said, sushi, cheese, and the occasional glass of wine were all okay during those nine long months. It gave us the much needed calm we needed during a time of so much uncertainty. With her two subsequent books Cribsheet and The Family Firm, Oster popularized a new phenomenon that has defined our generation of parents: data-driven parenting. It ditches the long lists of paternalistic rules, and instead examines peer-reviewed evidence and lets parents make their own informed decisions about their kids based on risks and tradeoffs.Nowhere was the Oster mentality more front and center, and more divisive, than during Covid. She argued very early on in the pandemic for less draconian and more nuanced policies. She wrote pieces in the Atlantic like, Schools Aren’t Superspreaders and Your Unvaccinated Kids Is Like A Vaccinated Grandma, when those words were considered heresy. And while she made quite a few enemies on the left over the last few years, recently she wrote Let’s Declare A Pandemic Amnesty, and earned herself some enemies on the right as well.Today, my wife Nellie Bowles joins me to talk to Oster about why a Harvard-educated economist at Brown University decided to become a parenting guru, how she used her parenting framework to become a leading expert on pandemic policies, and the unwinnable position of… actually following the science.Learn more about your ad choices. Visit megaphone.fm/adchoices
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 370: Sam Parr (@TheSamParr) talks to best-selling author, podcaster, bookstore owner, and former marketing director for American Apparel, Ryan Holiday (@RyanHoliday), about how to make money in publishing, creating a masterpiece, and investing in a ghost town.-----Links: Ryan Holiday * Trust Me I'm Lying: Confessions of a Media Manipulator Brass Check The Painted Porch Bookshop Vinyl Me, Please Ghost Town Living * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(03:55) - Does the bestseller list still matter?(05:30) - Breaking down the #s of the publishing industry(29:20) - How big is your team?(35:10) - Who do you admire?(44:40) - The pros and cons of reality distortion fields(50:40) - Ryan's ghost town-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can’t be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanHelix Sleep: https://helixsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanTimestamps(00:00:00) Supplements(00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol(00:11:51) Momentous, LMNT, Helix Sleep(00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins(00:21:07) Supplement Considerations: Cost, Nutrition & Schedule(00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens(00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition(00:33:06) Supplements for Gut Microbiome, Brain Fog(00:35:59) InsideTracker(00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements(00:38:35) Core Supplement Questions & Meeting Foundational Needs(00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine(00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin(00:55:55) Melatonin Caution(00:58:11) Supplement Dependency?, Placebo Effects(01:02:45) AG1 (Athletic Greens)(01:03:53) Nutrition & Behavior for Hormone Health(01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root (01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions (01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork (01:23:06) Testosterone Supplement: Tongkat Ali, Libido (01:27:24) Menstrual Cycle, Birth Control & Fertility(01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine (01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine(01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements(01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids(01:47:25) Food-Mimic Supplements, Protein (01:50:09) Kids, Aging & Supplements(01:55:25) A Rational Supplementation Protocol(01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterDisclaimerTitle Card Photo Credit: Mike Blabac
Masters in Business: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Bloomberg Radio host Barry Ritholtz speaks with the legendary John Mack, former chief executive officer and chairman of the board at Morgan Stanley. His memoir of his life and 34-year tenure at Morgan Stanley — “Up Close and All In: Life Lessons From a Wall Street Warrior” — was published in October.
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Rich Roll Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------As 2022 comes to a close and a new year beckons, we are presented with an opportunity to reflect on the past twelve months. Explore new aspirations. And set intentions for the year to come. Allow me to indulge this truth by introducing Part Two of my annual yearbook—an auditory anthology of the year’s most compelling conversations. Enjoy the best of the year.
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Peace + Plants,
Rich
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Big Questions with Cal Fussman: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------On the day of Pele’s burial, Cal goes to the archives for an interview he did with the man many consider to be the greatest soccer player of all time. This podcast gets to the essence of the Brazilian superstar who connected with almost everyone on the planet. Not only did Pele make everyone smile, he once halted a war. After three years of disconnection due to the pandemic, we need to connect now more than ever. Pele shows us how.
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------We’ve landed.
After 3 months of stealth mode, sneak-peeks, and surprise announcements, we have finally hit launch day.
In this special episode of Infinite Loops, hosted by Patrick O’Shaughnessy, Jim chats through the rationale behind founding OSV, the positive impact he wants it to have on the world, and the ways you can get involved.
Important Links:
Show Notes:
Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- View the Show Notes Page for This Episode
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Sign Up to Receive Peter’s Weekly Newsletter
Chris Hemsworth, best known for his role as Thor in the Marvel movies, joins Peter to discuss his recent work in the docuseries called Limitless. In the docuseries, Chris undertook extreme challenges to explore his physical and emotional limits and gain insights into longevity. In this episode, Chris discusses these many challenges—from fasting to arctic swims to 100-foot rope climbs—as well as the insights that he gained from each. Peter, who also played a role in the docuseries, guides Chris through the science of longevity, including what Chris’s APOE-ε4 genotype means for his risk of Alzheimer’s disease. Additionally, Chris describes how his outlook on health, happiness, work-life balance, and more have changed from his experience on Limitless.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
Starting Greatness with Mike Maples: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------More than fifty years after the first Concorde took flight, consumer air travel is actually SLOWER. Blake Scholl and his team at Boom Supersonic are out to reverse this stagnation and change how we think about commercial aviation. In this episode, Mike Maples, Jr of FLOODGATE interviews Scholl to learn more about the history of American aviation, the origins of Boom Supersonic and the challenges it faces now, and how tech founders are exploring unfamiliar spaces with great success.
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 398: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk to Morning Brew CEO Austin Rief (@austin_rief) about building, growing and selling a newsletter valued at $75M in 5 years, discussing the question are newsletters still worth doing, and a few good side hustle ideas to start now.-----Links: Morning Brew * Toptal Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(01:00) - Morning Brew origin story(19:10) - ad sales(24:10) - Austin's strengths(32:15) - Austin's upbringing(42:55) - what did you do with your new found wealth?(45:55) - ideas brainstorm(01:13:14) - future plans-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain how the brain engages in creative thinking and, based on that mechanistic understanding, the tools to improve one’s ability to think creatively and innovate in any area. I discuss how convergent and divergent thinking are essential for generating creative ideas and provide three types of meditation tools (open monitoring meditation, focused attention meditation & non-sleep deep rest; NSDR), which improve our ability to engage in these creative thinking patterns in specific and powerful ways. I also discuss how dopamine and mood contribute to the creative process and describe behavioral, nutritional and supplementation-based approaches for increasing dopamine to engage in creative thought and implementation. I explain how movement and storytelling (narrative) approaches can generate novel creative ideas and how substances like alcohol, cannabis, and psilocybin impact our creative ability. Excitingly, creativity is a skill that can be cultivated and enhanced; this episode outlines many tools to help anyone access creativity and apply creative patterns of thought to different domains of life.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanROKA: https://www.roka.com/hubermanThesis: https://takethesis.com/hubermanLMNT: https://drinklmnt.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanFor the full show notes, visit hubermanlab.comTimestamps(00:00:00) Creativity(00:04:30) ROKA, Thesis, LMNT, Momentous(00:08:51) What is Creativity?(00:11:16) Creativity in Visual Arts, Escher & Banksy(00:23:37) Neural Circuits of Creativity(00:31:58) AG1 (Athletic Greens)(00:33:13) Creative Ideas & Divergent Thinking(00:42:09) Testing Creative Ideas & Convergent Thinking(00:46:41) Dopamine, Convergent & Divergent Thinking Pathways(00:57:02) InsideTracker(00:58:06) Tool: Open Monitoring Meditation & Divergent Thinking(01:07:38) Tool: Focused Attention Meditation & Convergent Thinking(01:11:06) Mood, Creativity & Dopamine(01:16:00) Tool: Mood Calibrating, Caffeine & Dopamine(01:23:41) Dopamine Supplementation; L-Tyrosine, Caffeine(01:30:15) Tool: Non-Sleep Deep Rest, Mesocortical Dopamine & Divergent Thinking(01:43:130 Serotonin, Psylocibin & Creative Thinking(01:49:13) Alcohol & Autobiographical Scripting; Cannabis(01:52:04) Attention Deficit Hyperactivity Disorder (ADHD) & Creativity(01:54:45) Tool: Movement & Divergent Thinking(02:01:02) Tool: Narratives & Storytelling for Creativity(02:14:47) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social MediaDisclaimerTitle Card Photo Credit: Mike Blabac
Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- View the Show Notes Page for This Episode
Become a Member to Receive Exclusive Content
Sign Up to Receive Peter’s Weekly Newsletter
Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder and powerlifter, and two-time previous podcast guest. In this episode, Layne discusses his training as a powerlifter and shares training principles that non-powerlifters can apply to improve muscle strength and mass. Layne goes in-depth on creatine supplementation, including the benefits for lean mass and strength, and addresses the common arguments against its regular usage. Additionally, Layne touches on many areas of nutrition, including how his opinions have changed on certain topics. Layne also touches on the subjects of protein, fiber, and fat in the diet, as well as the different tools and dietary approaches for energy restriction.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
The Daily Stoic: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- It is amazing that Meditations, year after year and read after read, feels both incredibly timely and incredibly timeless (there’s a reason the book has endured now for almost twenty centuries).
It’s amazing that a person so famous—known to millions in his own lifetime and subject to countless books and articles and movies—could still be giving off new secrets, but indeed that’s what he’s doing.
Today, we examine 18 things you didn’t know that shaped the life of that person, Marcus Aurelius.
📕 We created a premium leather-bound edition of Meditations. To learn more and to pick up your own copy of this beautiful new edition of Meditations, visit dailystoic.com/meditations
✉️ Sign up for the Daily Stoic email: dailystoic.com/dailyemail
🏛 Check out the Daily Stoic Store for Stoic inspired products, signed books, and more.
📱 Follow us: Instagram, Twitter, YouTube, TikTok, Facebook
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
BiggerPockets Real Estate Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- Rob Dyrdek is one of the most well-known pro skaters, entrepreneurs, and media figures of all time. He essentially owned the MTV lineup for years with hit shows such as Rob & Big, Rob Dyrdek's Fantasy Factory, and Ridiculousness. At first glance, Rob may look like a phenomenal skater who turned his passion into something profitable. But behind the half pipes is an almost unbelievable amount of discipline, wisdom, and time optimization that only a select few know about.
Rob, like many entrepreneurs, ditched school early on when he realized that his talents were best used elsewhere. He left high school at sixteen, went on to compete in the highest level of skateboarding, and started his first company at seventeen. He was bringing in millions of dollars a year at an age where money is almost incomprehensible. Rob was fueled by creation, starting dozens of businesses that were doing millions in revenue but weren’t making a financial difference in his life. So, he took a high-level view of what was worth keeping and cut out everything but that.
From then on Rob began investing down two major avenues—businesses and real estate. Most people who follow Rob know about the former, but very few know about the latter. Now, Rob’s on the show to help us celebrate the 700th episode of the BiggerPockets Real Estate Podcast and show us how we too can make millions of dollars by tracking every minute of our day as intelligently as possible.
In This Episode We Cover:
Becoming an entrepreneur and Rob’s earliest business ventures
Why quantity over quality is key when building businesses and brands
Real estate syndications and why Rob will only touch a certain type of property
The “soul-sucking” landlord life and why it is NOT for everyone
Rob’s recession-proof plan that will make him millions even as investing fear peaks
Tracking your life and how doing so will make you richer and happier almost automatically
Building your financial framework and how so many doors open after you do so
And So Much More!
Links from the Show
Find an Investor-Friendly Real Estate Agent
BiggerPockets Youtube Channel
BiggerPockets Forums
BiggerPockets Pro Membership
BiggerPockets Bookstore
BiggerPockets Bootcamps
BiggerPockets Podcast
BiggerPockets Merch
Listen to All Your Favorite BiggerPockets Podcasts in One Place
Learn About Real Estate, The Housing Market, and Money Management with The BiggerPockets Podcasts
Get More Deals Done with The BiggerPockets Investing Tools
Find a BiggerPockets Real Estate Meetup in Your Area
David's BiggerPockets Profile
David's Instagram
David’s YouTube Channel
Rob's YouTube
Rob's Instagram
Rob's TikTok
Rob's Twitter
Rob's BiggerPockets Profile
Why Elite Investors Know Exactly How Much Their Time Is Worth
Syndications and Everything You Need to Know BEFORE You Invest
Here’s What It Takes to Succeed as an Entrepreneur
Connect with Rob Dyrdek:
Rob's Website
Rob's Instagram
Rob's Twitter
Rob's Podcast
Click here to check the full show notes: https://www.biggerpockets.com/blog/real-estate-700
Interested in learning more about today’s sponsors or becoming a BiggerPockets partner yourself? Check out our sponsor page!
See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Lenny's Podcast: Product | Growth | Career✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Chris Hutchins recently left his position as Head of New Product Strategy at Wealthfront to focus full-time on his podcast, All the Hacks.If you’re thinking about starting your own podcast or are simply interested in the process, be sure to check out today’s episode. We dive deep on all things podcasting: the pros and cons, how to climb the charts, and how much time you should expect to spend on each episode from start to finish. We talk in-depth about the process, from pre-production to publication, and share all of the products we use for recording, editing, and publishing. Chris also offers some important tips and tricks on how to get your first subscribers and how to market and grow your podcast, as well as some incredible money-saving hacks that you can start implementing today.
—
Find the full transcript here: https://www.lennyspodcast.com/launching-and-growing-a-podcast-chris-hutchins-all-the-hacks-wealthfront-google/#transcript
—
Thank you to our wonderful sponsors for supporting this podcast:
• Notion—One workspace. Every team: https://www.notion.com/lennyspod
• Vanta—Automate compliance. Simplify security: https://vanta.com/lenny
• Lenny’s Job Board—Hire the best product people. Find the best product gigs: https://www.lennysjobs.com/talent
—
Where to find Chris Hutchins:
• Twitter: https://twitter.com/hutchins
• LinkedIn: https://www.linkedin.com/in/chrishutchins/
• Website: https://chrishutchins.com/
—
Where to find Lenny:
• Newsletter: https://www.lennysnewsletter.com
• Twitter: https://twitter.com/lennysan
• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/
—
Referenced:
• All the Hacks podcast: https://www.allthehacks.com/
• All the Hacks newsletter: https://allthehacks.com/email
• Andy Rachleff on Twitter: https://twitter.com/arachleff
• Kerri Walsh Jennings on All the Hacks: https://www.allthehacks.com/performance-psychology-kerri-walsh-jennings/
• Descript: https://www.descript.com/
• Erika Taught Me podcast: https://podcasts.apple.com/us/podcast/erika-taught-me/id1650076906
• Leigh Rowan on All the Hacks: https://www.allthehacks.com/travel-hacks-leigh-rowan/
• Kevin Kelly’s “1,000 True Fans”: https://kk.org/thetechnium/1000-true-fans/
• Emily Oster’s books: https://emilyoster.net/writing/
• Chris Hutchins on The Kevin Rose Show: https://podcast.kevinrose.com/guests/chris-hutchins/
• Nick Gray’s newsletter: https://nickgray.net/signup-for-email-updates/
• The 2-Hour Cocktail Party: How to Build Big Relationships with Small Gatherings: https://www.amazon.com/2-Hour-Cocktail-Party-Relationships-Gatherings-ebook/dp/B0B2KW6T7J
• MrBeast on YouTube: https://www.youtube.com/channel/UCX6OQ3DkcsbYNE6H8uQQuVA
• Gary Vaynerchuk on Twitter: https://twitter.com/garyvee
• The Danny Miranda Podcast: https://podcasts.apple.com/us/podcast/the-danny-miranda-podcast/id1532160275
• Ray Dalio on Twitter: https://twitter.com/RayDalio
• Danny Miranda’s newsletter on Substack: https://dannymiranda.substack.com/
• ATRX2100 mic bundle on Amazon: https://www.amazon.com/Audio-Technica-ATR2100X-USB-Microphone-Bundle-Filter/dp/B082SYHRY9/r
• Riverside: https://riverside.fm/
• Focusrite Scarlett 2i2 on Amazon: https://www.amazon.com/Focusrite-Scarlett-Audio-Interface-Tools/dp/B07QR73T66
• Sony Alpha 7C mirrorless full-frame camera on Amazon: https://www.amazon.com/Sony-Alpha-Full-Frame-Mirrorless-Camera/dp/B08HVZLQ4F
• Adobe Audition: https://www.adobe.com/products/audition.html
• Pro Tools: https://www.avid.com/pro-tools
• Podpage: https://www.podpage.com/
• Simplecast: https://www.simplecast.com/
• Chartable: https://chartable.com/
• Podstatus: https://podstatus.com/
• Overcast: https://overcast.fm/
• Happy Money: https://www.amazon.com/Happy-Money-Ken-Honda-audiobook/dp/B07MJHJ57T/
• Vagabonding: An Uncommon Guide to the Art of Long-Term World Travel: https://www.amazon.com/Vagabonding-Uncommon-Guide-Long-Term-Travel/dp/0812992180
• Die with Zero: https://www.amazon.com/Die-Zero-Getting-Your-Money/dp/0358099765
• Animal Spirits Podcast: https://podcasts.apple.com/us/podcast/animal-spirits-podcast/id1310192007
• Mythic Quest on AppleTV+: https://tv.apple.com/us/show/mythic-quest
• Unclaimed money: https://www.usa.gov/unclaimed-money
• Savendeals.com: https://www.savendeals.com/
—
In this episode, we cover:
(00:00) Chris’s background
(03:25) Lesson’s from Wealthfront
(09:25) Why storytelling and communication are every bit as important as the product
(11:04) Why you need to understand the user’s experience and keep up with what others are building
(14:56) Why you should focus on overall impact, not just doing what your boss wants
(17:39) Why Chris likes working on big, crazy ideas
(19:10) The early days of Chris’s All the Hacks podcast
(21:34) The pros and cons of starting a podcast
(24:19) The time required to produce an episode
(27:09) How Lenny started his podcast
(28:29) Launch lessons and how Apple rankings work
(30:49) Why you need to create authentic content
(32:57) Be one person’s favorite podcast
(35:01) How Chris ideated and titled All the Hacks
(40:09) How to get started and get your first subscribers
(43:52) How Gary Vaynerchuk used Twitter to establish authority
(45:07) How to take advantage of platforms with built-in growth engines
(47:42) The power of in-person interviews
(48:57) How to pitch to other podcasts
(51:27) Equipment and products for producing podcasts
(57:36) How many downloads it takes in order to be taken seriously
(1:01:28) Using Overcast as a growth lever
(1:09:02) Lightning round
—
Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.
Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe
Aarthi and Sriram's Good Time Show✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------This week's special guest is Steven Sinofsky, one of our favorite techno-optimists responsible for shipping Windows and Office products at Microsoft used by billions of people. He is also the author of one of the most popular Substack books - https://hardcoresoftware.learningbyshipping.comIn this episode we talked about Steven's early days at Microsoft, his famous internet memo, working with Bill Gates, and the traits he sees in good leaders and founders, how to set company culture, his experience leading Office and Windows teams at Microsoft, and the secret behind his ability to write well.
How Leaders Lead with David Novak✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Welcome to How Leaders Lead where every week, you get to listen in while I interview some of the VERY best leaders in the world. I break down the key learnings so that by the end of the episode, you’ll have something simple you can apply as you develop into a better leader. That’s what this podcast is all about!Today’s guest is Stanley Druckenmiller, the #1 investor in the world.I know, that’s a big claim! But get this: during his 30 years managing money for investors, he had an average annual return of 31%. And he NEVER had a down year. So if you’re even a little interested in finance, you’re going to learn a lot from Stan – including some really practical investment advice and his take on the future of our economy.But more importantly, there’s a huge leadership lesson to learn. Stan isn’t afraid to envision the future differently than other people. He can see trends and patterns others can’t – and then he has the courage to act on them.That’s a skill EVERY leader needs to develop. Seeing the future differently allows us to spot opportunities and prepare for what’s coming. If we just go with the flow of what’s current, we’ll always just be a part of the trend, not ahead of it. You’re about to see for yourself how great leaders aren’t afraid to see the future differently.So here is my conversation with my good friend, and soon to be yours, Stanley Druckenmiller.
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- Ben Chestnut is the Co-Founder of Mailchimp, the all-in-one marketing platform for small businesses. Last year, in Sept 2021 it was announced that Intuit would acquire Mailchimp for a reported $12BN. There are so many things to love about the Mailchimp journey to this point. First, Mailchimp was founded as the result of a side project of a design agency Ben and his co-founder, Dan, used to run. Second, Mailchimp is and has always been based in Atalanta, eschewing the notion you have to be in SF or NYC to build a massive business. Then third, they never raised venture funding for the business all the way until their $12BN acquisition. Ben led Mailchimp to over 1,200 employees and millions of global users.
In Today's Episode with Ben Chestnut We Discuss: 1. From Mama's Kitchen to the Smell of Business and Founding Mailchimp:
Ben's fishing trips with his father played a big role in his early years, what were the single biggest lessons for Ben from his fishing trips with his father?
Ben Chestnut: The Leader:
How does Ben define the term "high performance" in leadership?
What does Ben mean when he says he used to have a "hands off, eyes off" leadership style? What have been the single biggest drivers in his development as a leader?
Ben Chestnut: The Person:
Relationship to Money: How does Ben reflect on his relationship to money? How has it changed over time? Why does Ben still to this day buy lottery tickets with his wife?
Potential Lost Identity: A founder's identity is so closely tied to their company, how did Ben manage the challenge of selling his company but retaining his identity? What did Ben learn about himself through many different acquisition processes?
Mailchimp: The Business:
Why did Ben never raise venture money in the 21 year journey of Mailchimp?
Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Dr. Brad Schoenfeld is a professor at Lehman College in the Bronx, in New York City. His research primarily focuses on muscle adaptations to strength training, muscle hypertrophy. Publishing over 300 studies in the field of exercise and sports nutrition as a scientist, Brad began his career as a competitive bodybuilder and personal trainer.
In this episode, we discuss:
Watch this episode on YouTube
Show notes are available by clicking here
Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter
Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/premium
Learn more about the premium podcast The Aliquot:
https://www.foundmyfitness.com/aliquot
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 390: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about Eric Langan and his foray into owning strip clubs, why we should boycott Black Friday, three Twitter scenarios, how to fly on a private jet and much, much more.-----Links: Jettly r/fatFIRE Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(03:20) - Eric Langan(12:50) - Black Friday(18:40) - Twitter(36:10) - George Hotz(48:10) - Private jets(53:00) - fatFIRE subreddit-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 382: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk to Kevin Rose (@kevinrose), entrepreneur, founder, VC and CEO of many projects, about creating an online magazine that garners $100M/year focusing on watches, what projects he's interested in, why he loves crypto, and where he invests his money.-----Links: Kevin Rose DIGG Proof Hodinkee agelessRx Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(03:15) - Kevin's background(13:40) - Meeting Mark Zuckerberg early in his career(26:15) - Beginnings of Hodinkee(33:55) - What gets you excited?(39:00) - What ideas/projects are you interested in?(50:30) - Web3 debate(53:40) - Crypto(01:13:05) - Portfolio-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest is Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health. We discuss how to optimize male hormones using a range of nutritional and behavioral tools, exercise, and supplementation (including discussions on tongkat ali, fadogia agrestis, creatine, peptides and more). We explain how puberty and aging affect hormone levels, how to use bloodwork to monitor hormone levels, how hormone health impacts fertility, libido, hair loss, and prostate health, and describe behaviors that negatively impact testosterone levels. We also discuss how to approach prescription hormone therapies, including which biomarkers to monitor when using these approaches and how to optimize synergistic hormones (e.g., growth hormone and thyroid hormone) to support complete hormone health safely and rationally. Dr. Gillett offers numerous actionable tools that can be tailored to specific goals and age ranges to attain and maintain optimal levels of male hormones for overall health, well-being and longevity. Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanThesis: https://takethesis.com/hubermanROKA: https://www.roka.com/hubermanHelix Sleep: https://helixsleep.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanFor the full show notes, visit hubermanlab.comTimestamps(00:00:00) Dr. Kyle Gillett & Male Hormone Optimization(00:03:40) Thesis, ROKA, Helix Sleep, Momentous(00:07:43) Puberty: Height, Resistance Training, Childhood Obesity(00:15:14) “First” vs. “Second” Puberty(00:17:17) Hormone Optimization & Blood Work(00:22:14) Diet, Exercise, Sleep & Hormones(00:28:23) Hormones, Stress, Social Connection & Purpose(00:32:19) Hormones, Supplementation & Medication(00:34:08) Determining Individual Hormone Levels, ADAM Questionnaire(00:40:35) Libido, Masturbation, Pornography & the Dopamine “Wave Pool”(00:48:32) AG1 (Athletic Greens)(00:49:46) Sustainable Exercise Regimen for Hormone Health(00:58:12) Testosterone Replacement Therapy (TRT)(01:01:02) Supplementation: Creatine & Hair Loss, Betaine, L-Carnitine & Allicin (Garlic)(01:11:45) Vitamin D, Boron; SHBG & Free Testosterone(01:15:34) InsideTracker(01:16:39) Tongkat Ali (Eurycoma longifolia; Longjack) & Steroid Pathways(01:22:09) Fadogia Agrestis & Testosterone (01:26:32) Optimize Growth Hormone & IGF-1: Diet, Fasting, Supplements & Exercise (01:31:52) Optimize Thyroid Hormone: Iodine & Goitrogens(01:33:56) Peptides: Growth Hormone, Tesamorelin, Ibutamoren & Gut Microbiome(01:42:06) Testosterone Therapy(01:47:03) Prescriptions & Hormones: Human Choriogonadotropin (HCG), Clomiphene(01:52:56) Testosterone Therapy + HCG, Fertility & Temperature(01:55:30) Hormone Health Q&A: Marijuana, Nicotine, Cycling, Pelvic Floor, Alcohol, Fat(02:06:08) Prostate Health & Tadalafil, Prostate Specific Antigen (PSA)(02:09:56) Hair Loss & DHT; Turmeric & Curcuminoids(02:18:13) BPAs, Phthalates & Hormone Health(02:21:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous, Neural Network NewsletterDisclaimerTitle Card Photo Credit: Mike Blabac
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Episode 394: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk with entrepreneur and Kayak co-founder, Paul English (@englishpaulm) about his latest business ideas, his famous missed investments, how to become a strong recruiter, and why he wants to create Twitter's competitor.-----Links: Paul English Boston Venture Studio * Middle * Bipolar Social Club Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. Want more insights like MFM? Check out Shaan's newsletter.------Show Notes:(00:25) - switched jobs for a day(07:05) - who did you know before they met success(13:45) - become an excellent recruiter(20:25) - starting a company easier now?(28:15) - Irritation becomes inspiration(30:55) - Ideas he's working on(34:10) - Bipolar disorder-----Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.-----Additional episodes you might enjoy:• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits• #209 Gary Vaynerchuk - Why NFTS Are the Future• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett• #218 - Why You Should Take a Think Week Like Bill Gates• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Max Lugavere is a health and wellness expert, author and a diet advocate.
Working out what to eat is hard. Which is odd because everybody does it. You'd think that the science of nutrition, a thing the entire human race relies on multiple times per day, would have some definitive answers. Thankfully Max can explain why it's such a mess and give some solid principles we can all use.
Expect to learn whether carnivore is an optimal diet for us all to follow, whether organic and non-GMO actually makes that much of a difference, what to look for in a magnesium supplement, the actual science of seed oils, whether sunscreen is a danger, why nutrition science is so contested, why calories matter but they aren't all that matter and much more...
Sponsors:
Get 83% discount & 3 months free from Surfshark VPN at https://surfshark.deals/MODERNWISDOM (use code MODERNWISDOM)
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Extra Stuff:
Check out Max's website - https://www.maxlugavere.com/
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Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/
To support me on Patreon (thank you): https://www.patreon.com/modernwisdom
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Get in touch.
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Email: https://chriswillx.com/contact/
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------In this episode, I explain how to use caffeine to enhance mental and physical health and performance, including the optimal dosages and intake schedules for caffeine. I explain how caffeine powerfully reinforces the consumption of certain foods and drinks—thereby increasing how much we like their tastes and seek them out. I discuss the mechanisms by which caffeine increases focus, alertness and mood and reduces sleepiness. I also explain many practical tools for caffeine use, including delaying caffeine intake after waking, intermittent caffeine use, during fasting, before and during exercise, and the use of theanine to curb jitters caused by caffeine. I also discuss the positive effects of caffeine on overall health and longevity and address several myths about caffeine. Since caffeine is one of the most commonly used substances (more than 90% of adults use caffeine daily!), this episode provides actionable tips for adjusting caffeine consumption to positively impact performance and health, including sleep.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLevels: https://levels.link/hubermanEight Sleep: https://www.eightsleep.com/hubermanROKA: https://www.roka.com/hubermanInsideTracker: https://www.insidetracker.com/hubermanSupplements from Momentoushttps://www.livemomentous.com/hubermanFor the full show notes, visit hubermanlab.comTimestamps(00:00:00) Caffeine(00:02:58) Tool: GLP-1, Yerba Mate, Satiety & Weight Loss(00:11:06) Levels, Eight Sleep, ROKA, Momentous Supplements(00:15:23) Caffeine Benefits for Mental & Physical Performance(00:20:23) Caffeine in Nature & Positive Reinforcement(00:26:44) Caffeine Effects on Brain; Reward Pathways(00:29:55) Caffeine as a Reinforcing Agent(00:36:47) AG1 (Athletic Greens) (00:38:01) Caffeine, Adenosine & Reduced Sleepiness (00:45:16) Tool: Caffeine Dosage, Caffeine Adapted(00:53:44) Tool: Delayed Caffeine Intake, Afternoon Crash & Sleep(01:04:46) Morning Exercise & Residual Caffeine Effects(01:07:56) Tool: Theanine & Jitteriness; Fasting, Intermittent Caffeine Use (01:13:00) Theanine: Effects & Dosage(01:18:41) InsideTracker(01:19:45) Other Effects: Osteoporosis, Hormone Levels, Depression(01:27:41) Afternoon Caffeine & Sleep(01:31:45) Tool: Caffeine & Mental/Physical Performance; Cortisol & Caffeine Abstinence(01:46:04) Caffeine, Performance & Menstrual Cycle(01:47:27) Tool: Memory & Caffeine Timing; Adrenaline & Cold Exposure(01:54:08) Caffeine & Naps(01:56:34) Tool: Exercise, Caffeine, Dopamine & Positive Reinforcement (02:01:55) Dopamine Stacking(02:06:04) Scheduling Caffeine to Maximize Its Effects(02:08:33) Pro-Health Effects of Caffeine(02:13:38) Tool: Sugar Cravings & Reinforcing Effects of Caffeine (02:20:17) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous Supplements, Neural Network NewsletterDisclaimerTitle Card Photo Credit: Mike Blabac
Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------When the 20-year-old overachiever Johnathan Bi's first startup crashed and burned, he headed to a Zen retreat in the Catskills to "debug himself." He discovered René Girard and his mimetic theory--the idea that imitation is a key and often unconscious driver of human behavior. Listen as entrepreneur and philosopher Bi shares with EconTalk host Russ Roberts what he learned from Girard and Girard's insights into how we meet our primal need for money, fame, and power. The conversation includes the contrasts between economics and Girard's perspective.
A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
When Neal Stephenson coined “the metaverse” three decades ago, his book Snow Crash was found on the shelves of “science fiction”. While the book remains in that category, many of its concepts are now found in reality…
Fast forward to 2022, where numerous companies are now building toward their version of the metaverse, including Neal himself – working on Lamina1 – a blockchain company oriented toward creators.
While the present metaverses don’t perfectly mimic that from Stephenson’s early imagination, we get the unique opportunity to discuss the various design decisions that he’s making, but also the intersection between the metaverse and gaming, the involvement that AR/VR might play, the evolving role of IP, how artificial intelligence fits in, what he’s building and why, and where he gets all of his ideas from.
Resources:
Neal’s Twitter: https://twitter.com/nealstephenson
Lamina1’s website: https://www.lamina1.com/
Stay Updated:
Find us on Twitter: https://twitter.com/a16z
Find us on LinkedIn: https://www.linkedin.com/company/a16z
Subscribe on your favorite podcast app:https://a16z.simplecast.com/
Follow our host: https://twitter.com/stephsmithio
Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.
MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom.
Related Links/Products Mentioned
People Mentioned
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Links: * Braintree * Kernel * Blueprint * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (03:25) - Background starting w/Braintree (15:30) - Financial plans and life changes (21:45) - Where do you put your money (27:05) - What does Kernel do (36:55) - Blueprint blog (57:40) - Goal alignment
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Chris Palmer, M.D., a board-certified psychiatrist and assistant professor of psychiatry at Harvard Medical School. He explains the important connection between nutrition, metabolism and mental health and his pioneering work using the ketogenic diet to successfully treat patients with various mental illnesses, including depression and schizophrenia. Dr. Palmer explains how the ketogenic diet is an evidenced-based treatment for epilepsy, mimics the fasted state and can offset the cognitive decline in Alzheimer’s. He describes the key roles of mitochondria in mental health, how certain conditions likely arise from mitochondrial dysfunction, and how low-carbohydrate diets increase mitochondrial turnover to improve mental health. He also explains how low-carbohydrate diets positively impact the gut microbiome and weight loss, important risk factors for mitochondrial health such as marijuana and alcohol, and the best way to increase circulating ketones depending on individual needs. We also cover how a ketogenic diet impacts mood, sleep, and fertility. Dr. Palmer’s work stands as a revolutionary approach to mental health and disease that, given the prevalence of mental health challenges, should be of interest to people of all backgrounds and ages. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Chris Palmer, Mental Health & Metabolic Disorders (00:03:25) Thesis, Eight Sleep, ROKA (00:07:18) Nutrition & Mental Health (00:20:43) Low-Carb Diets & Anti-Depression, Fasting, Ketosis (00:27:52) Schizophrenia, Depression & Ketogenic Diet (00:34:32) AG1 (Athletic Greens) (00:35:38) Psychiatric Mediations, Diet Adherence (00:42:35) Highly Processed Foods, Ketones & Mental Health Benefits (00:46:51) Ketogenic Diet & Epilepsy Treatment (00:56:10) Ketogenic Diet & Mitochondria Health (00:57:05) Nutrition & Benefits for Neurologic/Psychiatric Disorders (01:05:44) Mitochondrial Function & Mental Health (01:15:12) InsideTracker (01:16:23) Mitophagy, Mitochondrial Dysfunction, Aging & Diet (01:25:09) Neurons, Mitochondria & Blood Glucose (01:31:54) Obesity, Ketogenic Diet & Mitochondria (01:40:00) Mitochondrial Function: Inheritance, Risk Factors, Marijuana (01:46:34) Alcohol & Ketogenic Diet (01:55:21) Brain Imaging, Alzheimer’s Disease & Ketones (02:01:05) Exogenous (Liquid) Ketones vs. Ketogenic Diet (02:06:27) Neuronal Damage, Ketones & Glucose (02:10:16) Alzheimer’s Disease, Age-Related Cognitive Decline & Ketogenic Diet (02:23:45) Ketogenic Diet & Weight Loss (02:35:47) Ketogenic Diet & Fasting, Hypomania, Sleep (02:46:37) Low Carbohydrate Diets, Menstrual Cycles, Fertility (02:52:23) Obesity Epidemic, Semaglutide & GLP-1 Medications (03:01:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Social Media Disclaimer Title Card Photo Credit: Mike Blabac
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
“With enough curiosity, self-confidence is irrelevant.”
Tinkered Thinking is a writer, artist, author and creator. He is also the worthy winner of our ‘White Mirror’ competition.
His writing includes a series of ‘Lucilius Parables’, short stories dispersed throughout time and space designed to help readers reconceptualise their experience of being alive.
He joined the show to discuss writing, technology, curiosity, optimism and MUCH more!
Important Links:
Show Notes:
Books Mentioned:
Nudge - Marketing Science Simplified✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Today’s title sounds like clickbait, but that’s the point. In this show, I share the history of clickbait, why curiosity can make someone seem more attractive, the science behind memory, and how I got 11k followers on TikTok in just two weeks.
Listen to the episode “How I made a Reddit ad 15% more effective”: bit.ly/3E8jpYR The data behind the TikToks: https://bit.ly/3vd5QUg Robert Cialdini’s Pre-Suasion: https://amzn.to/3OvEYFB Sign up for my newsletter: https://www.nudgepodcast.com/mailing-list Try HubSpot for free: https://hubspot.sjv.io/jWq4k6
Lenny's Podcast: Product | Growth | Career ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Matt Mochary, CEO of Mochary Method, is a full-time executive coach who has worked with some of the biggest names in tech and finance, including investor Naval Ravikant and the CEOs of Notion, OpenAI, Coinbase, Reddit, and many others. In today’s podcast, we talk about the skill of firing people, why it’s so important, and Matt’s framework for approaching layoffs. We go deep on recognizing emotions like anger and fear, and what to pay attention to when you feel angry or fearful. He also shares how to build new products within a larger company, important tips on how to make sure everyone in the organization feels valued and heard, carving out time for your top goal, and how an energy audit can help you eliminate tasks that are draining your energy.
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Find the full transcript here: https://www.lennyspodcast.com/how-to-fire-people-with-grace-work-through-fear-and-nurture-innovation-matt-mochary-ceo-coach/#transcript
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Where to find Matt Mochary:
• Twitter: https://twitter.com/mattmochary
• LinkedIn: https://www.linkedin.com/in/matt-mochary-34bb4/
• Website: http://www.mochary.com/
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Where to find Lenny:
• Newsletter: https://www.lennysnewsletter.com
• Twitter: https://twitter.com/lennysan
• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/
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Thank you to our wonderful sponsors for making this episode possible:
• AssemblyAI: https://www.assemblyai.com/?utm_source=lennyspodcast&utm_medium=podcast&utm_campaign=nov10
• Lemon.io: https://lemon.io/lenny
• Vanta: https://vanta.com/lenny
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Referenced:
• The Great CEO Within: The Tactical Guide to Company Building: https://www.amazon.com/Great-CEO-Within-Tactical-Building-ebook/dp/B07ZLGQZYC
• Mochary Method: https://mocharymethod.org/
• Leo Polovets on Twitter: https://twitter.com/lpolovets
• High Output Management: https://www.amazon.com/High-Output-Management-Andrew-Grove/dp/0679762884
• The Hard Thing About Hard Things: Building a Business when There Are No Easy Answers: https://www.amazon.com/Hard-Thing-About-Things-Building/dp/0062273205
• Andrej Karpathy on Lex Fridman’s podcast: https://lexfridman.com/andrej-karpathy/
• Wei Deng on LinkedIn: https://www.linkedin.com/in/dengwei/
• Free Solo: https://films.nationalgeographic.com/free-solo
• Ryan Hoover on Twitter: https://twitter.com/rrhoover
• Essentialism: The Disciplined Pursuit of Less: https://gregmckeown.com/books/essentialism/
• Make Time: How to Focus on What Matters Every Day: https://www.amazon.com/Make-Time-Focus-Matters-Every/dp/0525572422
• Centered app: https://www.centered.app/
• Diana Chapman at Conscious Leadership Group: https://conscious.is/team/diana-chapman
• The Mochary Method curriculum doc: https://docs.google.com/document/d/18FiJbYn53fTtPmphfdCKT2TMWH-8Y2L-MLqDk-MFV4s/edit
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In this episode, we cover:
(04:43) Matt’s background
(07:39) Areas where even very successful founders struggle
(12:24) How to address people to minimize defensiveness
(13:24) The destructive nature of anger and how to feel your feelings so you don’t hurt others
(15:02) Which books led Matt to his coaching journey and software platform
(19:03) When and how to let an employee go
(31:47) How to make people feel heard
(38:05) How Matt’s coaching has evolved to include psychological obstacles to success
(39:41) What is “top goal,” and how can it help you make massive gains?
(41:25) Why Matt has an accountability partner for his top goal time
(43:44) How to approach mass layoffs humanely
(53:21) Matt’s thoughts on the Twitter layoffs
(54:10) How to innovate within a large company
(1:01:53) How to do an energy audit
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Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.
Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode is packed with wisdom from previous guests on the art of making better decisions.
We discuss the three types of decision-makers, how to control your emotions when making decisions, why it’s crucial to look at every decision differently, the processes for coming to the right decision, and how to learn from your mistakes when you get it wrong.
The guests on this episode are author Ventakesh Rao (Episode 7), psychologist, author and professional poker player Maria Konnikova (Episode 89), Stripe co-founder Patrick Collison (Episode 32), cognitive-behavioral decision science author and professional poker player Annie Duke (Episode 37), and Shopify co-founder Tobi Lutke (Episode 41). Transcript: https://fs.blog/knowledge-project-podcast-transcripts/tkp-insights-decision-making/ --
Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
Every Sunday, our Brain Food newsletter shares timeless insights and ideas you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/
Follow Shane on Twitter at: https://twitter.com/ShaneAParrish
Nudge - Marketing Science Simplified✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Julius Caesar is considered by most historians the greatest military commander of all time. You might know of his war strategies, battle tactics, and perhaps his career history. But I bet you don’t know how he convinced a continent’s population to follow him. Or how he made the region’s largest army adore him. In this episode, you’ll learn the leadership tactics that took Julius Caesar to the top. You’ll hear the methods he used to convince and influence others. You’ll discover applicable practices that you can use, and you’ll even hear the real reason why the humble potato is so popular. Try HubSpot for free: https://hubspot.sjv.io/jWq4k6 How To Take Over The World (Julius Caesar): https://bit.ly/3MPXkC8 My costly signalling experiment: https://i.im.ge/2022/10/21/2Nj6C0.Costly-Signal.png Listen to episode 63: https://bit.ly/3TnCKeN Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Layne Norton, Ph.D. — one of the world’s foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://www.drinklmnt.com/huberman ROKA: https://www.roka.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Layne Norton, Nutrition & Fitness (00:02:53) LMNT, ROKA, InsideTracker, Momentous (00:06:50) Calories & Cellular Energy Production (00:12:35) Energy Balance, Food Labels, Fiber (00:15:19) Resting Metabolic Rate, Thermic Effect of Food (00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT) (00:25:49) Losing Weight, Tracking Calories, Daily Weighing (00:29:24) Post-Exercise Metabolic Rate, Appetite (00:35:04) AG1 (Athletic Greens) (00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs (00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity (00:56:32) Weight Loss & Maintenance, Diet Adherence (01:03:33) Restrictive Diets & Transition Periods (01:08:03) Gut Health & Appetite (01:16:23) Tool: Supporting Gut Health, Fiber & Longevity (01:23:59) LDL, HDL & Cardiovascular Disease (01:30:31) Leucine, mTOR & Protein Synthesis (01:37:31) Tool: Daily Protein Intake & Muscle Mass (01:44:24) Protein & Fasting, Lean Body Mass (01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea (02:04:28) Processed Foods (02:11:54) Obesity Epidemic, Calorie Intake & Energy Output (02:17:33) Obesity, Sugar & Fiber, Restriction & Craving (02:25:57) Artificial Sweeteners & Blood Sugar (02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar (02:50:19) Rapid Weight Loss, Satiety & Beliefs (02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity (03:08:15) Females, Diet, Exercise & Menstrual Cycles (03:14:05) Raw vs. Cooked Foods (03:16:32) Berberine & Glucose Scavenging (03:19:12) Fiber & Gastric Emptying Time (03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea (03:30:33) Hard Training; Challenge & Mental Resilience (03:36:12) Carbon App (03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media Disclaimer: https://hubermanlab.com/disclaimer Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Welcome to a sneak peek of the first Ask Me Anything (AMA) episode, part of Huberman Lab Premium. The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation. Want your question answered? Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium Timestamps (00:00:00) Introduction (00:01:09) How do you use ultradian cycles in your daily work? [Jackson Lipfert] (00:22:38) Huberman Lab Premium In the full AMA episode, we discuss:
Neuroplasticity and dementias (Alzheimer's, MS, Parkinson's) — Protocols for protecting the brain?
Zone 2 training
What do you do when you live in a northern climate and the sun doesn't rise until hours after you are up?
Morning routine for people who work from 8 am to 5 pm
Best productivity method: to-do list or time-blocking everything on a calendar?
Seed oils and metabolic disease
Do recommendations and protocols you give change with age (beyond 60)?
What advice would you give to your younger self?
Social & Website Instagram: https://www.instagram.com/hubermanlab Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/hubermanlab TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://hubermanlab.com Newsletter: https://hubermanlab.com/neural-network Huberman Lab is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Title Card Photo Credit: Mike Blabac
Deep Questions with Cal Newport ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo
DEEP DIVE: The Two Types of Ambition [4:36]
How does Cal choose what books to read? [1:06:16]
What’s is Cal’s philosophy on caffeine? [1:15:12]
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Thanks to Jesse Miller for production, Jay Kerstens for the intro music, and Mark Miles for mastering.
The Danny Miranda Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Nik Sharma is a brand builder. He's the creator of Sharma Brands (a marketing agency that's worked with MrBeast and Emma Chamberlain). In this conversation, we spoke about not going to college, how he's used Twitter effectively, the two skills everyone should learn if they're about to graduate college, and how he got in contact with Mark Cuban via cold email.
(0:00) Bob The Builder
(2:16) Nik’s Childhood Teacher
(6:39) Skills To Learn
(9:49) Mark Cuban Email
(13:45) Vibes
(14:40) David Perell Friendship
(16:08) Saving Cousin’s Life
(18:49) Death
(21:11) Building A Brand
(26:55) Working With MrBeast
(33:30) Working With Emma Chamberlain
(37:04) Small Inflection Points
(40:45) Not Going To College
(47:00) Gary Vaynerchuk
(49:55) Scaling Sharma Brands
(53:39) Twitter
(59:20) Challenge
Nik's Links
Twitter: https://twitter.com/mrsharma
Cold Email Thread: https://twitter.com/mrsharma/status/1463205121979002890
My Links
✉️ Newsletter: https://dannymiranda.substack.com
🎙 Podcast: https://anchor.fm/dannymiranda
🎥 YouTube: https://youtube.com/dannymiranda
🐣 Twitter: https://twitter.com/heydannymiranda
📸 Instagram: https://instagram.com/heydannymiranda
🕺 TikTok: https://tiktok.com/@heydannymiranda
Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
The Twilight Zone is arguably one of the best and most influential shows in television history. The reason it endures, and is still being watched and talked about more than sixty years after its debut, can not only be traced to its superior storytelling and innovations in the genres of horror, science fiction, and fantasy, but the fact that each episode is embedded with a lesson on how to grapple with life's moral and existential dilemmas.
Here to unpack those life lessons is Mark Dawidziak, author of Everything I Need to Know I Learned in the Twilight Zone. Today on the show, Mark and I discuss the parable-like morals from a selection of Twilight Zone episodes, drawn from those that are my favorites, Mark's favorites, and simply classic. And, since Halloween is coming up, Mark and I both offer our picks for the just plain scariest episodes to watch.
Resources Related to the Episode Episodes referenced in the show: + "A Stop at Willoughby" + "Walking Distance" + "Time Enough at Last" + "A Nice Place to Visit" + "To Serve Man" + "Mr. Bevis" + "Kick the Can" + "The Monsters Are Due on Maple Street" + "The Obsolete Man" * Mark's picks for the scariest Twilight Zone episodes: + "Twenty Two" + "Ring-a-Ding Girl" * Brett's picks for the scariest Twilight Zone episodes: + "Living Doll" + "The Dummy" + "It's a Good Life" * AoM articles inspired by Twilight Zone* episodes: + Can’t Have the Sweet Without the Bitter (Inspired by "A Nice Place to Visit") + How Redundancies Increase Your Antifragility (Inspired by "Time Enough at Last") + Sunday Firesides: Things Don’t Get Old, We Do (The illustration is an Easter egg homage to "Walking Distance")
Connect With Mark Dawidziak* Mark's Website
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan is an angel investor, tech founder, philosopher, and author of The Network State: How to Start a New Country. He was formerly the CTO of Coinbase and General Partner at Andreessen Horowitz. Please support this podcast by checking out our sponsors: – Policygenius: https://www.policygenius.com/ – Blinkist: https://blinkist.com/lex to get 25% off premium – Notion: https://notion.com – Onnit: https://lexfridman.com/onnit to get up to 10% off EPISODE LINKS: Balaji’s Twitter: https://twitter.com/balajis Balaji’s Website: https://balajis.com Books: 1. The Network State: https://thenetworkstate.com 2. Reputation and Power: https://amzn.to/3eyQiF6 3. Exit, Voice, and Loyalty: https://amzn.to/3TpuLNP 4. Seeing Like a State: https://amzn.to/3MJfvcD Articles: 1. Bitcoin
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss the biological mechanisms of the state changes that occur during different types of mediation and describe how to develop the mediation practice optimal for you. I explain key meditation principles, such as using specific breathwork patterns and adjusting your perception to specific locations along the continuum between interoception, exteroception and dissociation. I discuss how meditation practices lead to long-term trait changes and neuroplasticity, including changing your default mood, reducing baseline anxiety/depression, increasing your ability to focus, enhancing relaxation, improving sleep, and increasing your overall happiness level. I also explain the concept behind the “third-eye center,” what mindfulness is from a biological standpoint, the power of ultra-brief meditations and how to select the best meditation and time and duration to meditate to meet your need. I also explain a novel open-eyed perception-based meditation that may enhance focus, relaxation and task-switching ability. Whether you are a novice or an experienced meditator or simply interested in how our brain controls different aspects of conscious awareness and self-regulation, this episode should interest you. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://www.insidetracker.com/huberman Thesis: https://takethesis.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Meditation (00:04:13) InsideTracker, Thesis, ROKA, Momentous Supplements (00:08:25) Brief History of Meditation: Consciousness, Psychedelics, fMRI (00:16:19) How the Brain Interprets the Body & Surrounding Environment; Mindfulness (00:26:07) Neuroscience of Mediation; Perceptual Spotlights (00:32:27) AG1 (Athletic Greens) (00:33:41) Interoception vs. Exteroception (00:42:20) Default Mode Network, Continuum of Interoception & Exteroception (00:53:30) Tools: Interoceptive or Exteroceptive Bias, Meditation Challenge (01:01:48) State & Trait Changes, Interoceptive & Exteroceptive Meditations, Refocusing (01:07:35) Tool: Brief Meditations, Waking Up App (01:10:30) “Third Eye Center” & Wandering Thoughts (01:20:46) Mediation: Practice Types, Focal Points & Consistency (01:24:10) Breathwork: Cyclic Hyperventilation, Box Breathing & Interoception (01:30:41) Tool: Meditation Breathwork, Cyclic vs. Complex Breathwork (01:39:22) Interoception vs. Dissociation, Trauma (01:47:43) Model of Interoception & Dissociation Continuum (01:53:39) Meditation & Dissociation: Mood, Bias & Corresponding Challenge (02:00:18) Meditation & Sleep: Yoga Nidra, Non-Sleep Deep Rest (NSDR) (02:11:33) Choosing a Meditative Practice; Hypnosis (02:14:53) Tool: Space-Time Bridging (STB) (02:25:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media Title Card Photo Credit: Mike Blabac Disclaimer
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Chris Sacca is the Founder and Chairman @ Lowercase Capital, one of the best performing funds in the history of venture capital with a portfolio including Uber, Stripe, Twitter, Instagram, Twilio, Docker and many more.
Chamath Palihapitiya is Founder & CEO @ Social Capital. Social’s portfolio includes the likes of Slack, Yammer, Front, Intercom and Carta to name a few.
Brad Gerstner is the Founder and CEO of Altimeter. Brad’s notable deals that he has helped lead include Snowflake, Mongo, Bytedance, Gusto, Unity, Okta, dbt, Modern Treasury, EPIC Games, Hotel Tonight and Zillow.
Cyan Banister is one of the most successful and renowned early-stage investors in the last decade. Her portfolio includes the likes of SpaceX, Uber, Affirm, Opendoor Postmates, Niantic and Thumbtack to name a few.
George Zachary is a General Partner @ CRV, one of the nation's oldest and most successful early-stage venture capital firms with a portfolio including the likes of Airtable, DoorDash, Dropbox, Niantic and many more.
Biz Stone is best known as the Co-Founder of Twitter and Medium. Biz is also an investor in the likes of Slack, Square, Intercom, Beyond Meat and Blue Bottle Coffee.
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Episode #380: Shaan Puri (@shaanvp) talks about the different kinds of luck, how to put yourself in a position to be lucky, and how to mitigate different kinds of risk. To submit your question and hear yourself on My First Million, go to MFMPod.com and click on the circle with the microphone in the lower right hand corner.
Links: * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Nudge - Marketing Science Simplified✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Jose Mourinho is one of the world's most successful football managers. He has consistently turned good teams into the world’s best. He’s done so by signing fantastic players, by mastering tactics, but also by using psychological mind games to motivate his players and undermine his opposition. In this episode, I share interviews with Mourinho to pick apart why he used mind games, what he aimed to achieve, and whether or not they really worked. Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list Follow me on Twitter: https://twitter.com/p_agnew Connect with me on LinkedIn: https://bit.ly/3mcmaiZ
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://www.levelshealth.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Eddie Chang, Speech & Language (00:03:00) Levels, Eight Sleep, InsideTracker, Momentous Supplements (00:07:19) Neuroplasticity, Learning of Speech & Environmental Sounds (00:13:10) White Noise Machines, Infant Sleep & Sensitization (00:17:26) Mapping Speech & Language in the Brain (00:24:26) Emotion; Anxiety & Epilepsy (00:30:19) Epilepsy, Medications & Neurosurgery (00:33:01) Ketogenic Diet & Epilepsy (00:34:56) AG1 (Athletic Greens) (00:36:10) Absence Seizures, Nocturnal Seizures & Other Seizure Types (00:41:08) Brain Areas for Speech & Language, Broca’s & Wernicke’s Areas, New Findings (00:53:23) Lateralization of Speech/Language & Handedness, Strokes (00:59:05) Bilingualism, Shared Language Circuits (01:01:18) Speech vs. Language, Signal Transduction from Ear to Brain (01:12:38) Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations (01:17:37) Mapping Language in the Brain (01:20:26) Plosives & Consonant Clusters; Learning Multiple Languages (01:25:07) Motor Patterns of Speech & Language (01:28:33) Reading & Writing; Dyslexia & Treatments (01:34:47) Evolution of Language (01:37:54) Stroke & Foreign Accent Syndrome (01:40:31) Auditory Memory, Long-Term Motor Memory (01:45:26) Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI) (02:02:14) Neuralink, BCI, Superhuman Skills & Augmentation (02:10:21) Non-Verbal Communication, Facial Expressions, BCI & Avatars (02:17:35) Stutter, Anxiety & Treatment (02:22:55) Tools: Practices for Maintaining Calm Under Extreme Demands (02:31:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer
CryptoThe Investor's Podcast (TIP): Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
IN THIS EPISODE, YOU’LL LEARN:
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
I describe a fitness protocol that maximizes all the major sought-after aspects of physical fitness, including strength, endurance and flexibility. I discuss fundamentals of resistance training protocols, including repetitions, sets, inter-set and inter-workout rest periods and periodization of intensity and volume to improve strength and hypertrophy. I also explain how to integrate this with endurance training across the week by controlling the duration, timing and intensity of cardiovascular workouts. I also cover science-based protocols on leveraging the mind-body connection, deliberate breathing (during and after exercise), stretching, deliberate heat and cold exposure, and non-sleep deep rest (NSDR) for better workout performance and faster recovery. Further, I tackle a range of real-world issues that can affect a consistent training schedule, such as whether you should train if you are sick, have had a poor night of sleep or had a stressful event and how to start training again after a break and whether you should train in a fasted or fed state. Physical fitness is a key variable for immediate and long-term health. This episode provides a modifiable “foundational” template that can be adjusted based on your current fitness level, goals, time constraints, and access to different types of equipment. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://www.roka.com/huberman Helix Sleep: https://www.helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Foundational Protocol for Fitness (00:03:35) Huberman Lab Premium (00:04:35) Tool: Soleus (Calf) Push-Ups, Glucose Utilization & Metabolism (00:14:42) InsideTracker, ROKA, Helix Sleep, Momentous Supplements (00:18:53) Core Principles of Fitness & Modifiable Variables (00:23:37) Day 1: Long Endurance Workout (00:34:38) Day 2: Leg Resistance Training, Strength & Hypertrophy (00:38:09) Athletic Greens (AG1) (00:39:22) Key Principles of Resistance Training (00:51:10) Day 3: Heat & Cold Exposure, Recovery (01:00:35) Day 4: Torso & Neck Resistance Training (01:09:55) Day 5: Moderate Intensity Cardiovascular Training, Running Alternatives (01:16:43) Day 6: High-Intensity Interval Training, Maximum Heart Rate (01:24:10) Day 7: Arms, Neck & Calves Resistance Training (01:28:45) Flexibility of Foundational Protocol, Workout Spacing (01:33:00) Tool: Mind-Muscle Contraction, Physiological Sighs (01:37:10) Safety & Endurance/Cardiovascular Workouts (01:38:32) Tool: Stress or Poor Sleep & Workouts, Recovery & NSDR (01:41:20) Should You Train Fasted or Fed? (01:43:58) Tool: Static Stretching & Flexibility, Irradiation & Resistance Training (01:49:10) Tool: Hanging from a Bar & Fitness Metric (01:50:16) Should You Train Sick?, Ramping Training (01:53:33) Tool: Deliberate Slow Breathing & Recovery (01:55:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer
HVMN Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Dr. Dominic D’Agostino is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). Dr. Angela Poff is a Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida in Tampa, FL, and Co-Founder of Metabolic Health Initiative. Dr. Latt Mansor and Geoff Woo met Dr. D’Agostino and Dr. Poff in person to talk about the state of the art of ketone research in 2022. Key point topics and studies mentioned: * Role of ketones and the future direction of ketone research in: + Athletic performance/ extreme environment + Mitochondrial protection in astronauts in space + Cancers + Metabolic psychiatry + Alzheimer’s and dementia
H.V.M.N. Podcast Fam: We're giving you an exclusive offer. You guys are some of our most loyal fans, and we want to give you a special reward. Use HVMNPOD10 to get 10% off your next H.V.M.N. order.
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Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Emad Mostaque is the founder and CEO of Stability AI, the company behind Stable Diffusion.
Emad joins Stability AI’s recently announced Executive Chair of the board of directors Jim O’Shaughnessy to discuss the future of AI, the benefits of open source software, and much more.
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LABOSSIERE PODCAST ✓
Claimed : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Samo Burja is the founder of Bismarck Analysis, a consulting firm that investigates the political and institutional landscape of society. He’s also a Research Fellow at the Long Now Foundation where he studies how institutions can endure for centuries and millennia.
Samo is also Senior Research Fellow in Political Science at the Foresight Institute, where he advises how institutions can shape the future of technology.
He writes and speaks on history, institutions, and strategy with a focus on exceptional leaders that create new social and political forms. He’s systematized this approach as “Great Founder Theory.”
James Altucher Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
After the unexpected and untimely passing of Coolio, we have decided to re-air this early episode of the podcast.
From the original release notes:
"Grammy Award-winning and multi-platinum artist Coolio joins The James Altucher Show to share his story of success. With more than 30 million records sold globally, Coolio gives a side to his story that most people don’t know.
Teacher? Psychologist? Author? There are many surprising career paths that Coolio he had interests in pursuing.
You’ll hear how his love of music and his ability to understand and connect with people enabled him to create hip-hop poetry unlike anyone else.
Something that most people don’t realize is that one of Coolio’s biggest hits, “Gangsta’s Paradise,” caused him some career conflicts, and here you get all the details.
What is truly inspiring is his passion for life and his ability to choose himself. From a rough childhood and being bullied to creating his career from scratch, you get the exclusive details from Coolio himself.
He is living proof that believing in yourself is a skill, one that everyone can master if they put their mind to it."
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Thank you so much for listening! If you like this episode, please rate, review, and subscribe to “The James Altucher Show” wherever you get your podcasts:
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, my guest is Nolan Williams, M.D., a triple board-certified psychiatrist, neurologist and professor of psychiatry and behavioral sciences at Stanford School of Medicine. He is also the Director of the Stanford Brain Stimulation Lab. We discuss clinical applications for brain stimulation, behavioral protocols and novel drug treatments to halt and reverse mental health disorders, including depression and post-traumatic stress disorder (PTSD). We first discuss the neural circuits for self-identity and mood and stress control. We discuss Dr. Williams’ work using transcranial magnetic stimulation (TMS) to depression, trauma, PTSD, and other mood disorders. We then dive deep into the history, biology, modern use, and safety margins of the various psychedelics, including MDMA, LSD, ketamine, ibogaine, ayahuasca, and psilocybin, as well as cannabis and the use of SSRIs in both adults and children. Finally, we discuss behavioral treatments for mental health disorders, including sleep and sleep deprivation, light exposure, exercise, and training to control the brain-heart-rate pathways. Regardless of age, all those interested in mental health should benefit from the incredible breadth and depth of Dr. Williams’ knowledge and the clarity with which he conveys that information. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Nolan Williams, Brain Stimulation & Depression Treatment (00:03:31) Huberman Lab Premium (00:04:42) InsideTracker, Eight Sleep, ROKA (00:08:37) Momentous Supplements (00:09:16) Depression, Risk Factors, Emergency Psychiatric Treatments (00:15:11) The Brain-Heart Connection, Vagus Nerve, Prefrontal Cortex (00:17:51) Right vs. Left Brain Hemispheres & Mood Balance, Connectome (00:22:34) Heart Rate & Depression, Behavioral Interventions, Transcranial Magnetic Stimulation (TMS) (00:33:02) Prefrontal Cortex & Cognitive Control, TMS (00:37:46) AG1 (Athletic Greens) (00:39:00) Belief/Identity “Rules”, Re-scripting, TMS & Talk Therapy (00:45:49) Dorsolateral Prefrontal Cortex, TMS & Depression Treatment (00:48:36) Cingulate Cortex & Emotion, Dissociation & Catatonia (00:54:27) Ketamine, the Opioid System & Depression; Psychedelic Experience or Biology? (01:03:42) SSRIs, Serotonin & Depression; Childhood, Chemical Imbalance or Circuit? (01:13:58) Memories & “Rule” Creation; Psilocybin & “Rule” Resolution (01:21:00) MDMA & Post-Traumatic Stress Disorder (PTSD) Treatment, Psilocybin & Depression Treatment (01:24:12) Is MDMA Neurotoxic?, Drug Purity, Dopamine Surges, Post-MDMA Prolactin (01:30:38) Psilocybin, Brain Connectivity & Depression Treatment (01:34:53) Exposure Response Prevention: “Letting Go” & Depression Treatment (01:41:23) Normal Spectrums for Mental Health Disorders (01:45:35) Ibogaine & “Life Review”; PTSD, Depression & Clinical Trials (01:57:16) Clinical Use of Psychedelics (02:01:59) Ayahuasca, Brazilian Prisoner Study (02:06:55) Cannabis: THC, CBD & Psychosis, Clinical Uses (02:14:52) Personal Relative Drug Risk & Alcohol (02:20:42) Circadian Reset for Depression, Sleep Deprivation, Light (02:28:43) Stanford Neuromodulation Therapy (SNT) Study (02:34:25) Space Learning Theory & TMS Stimulation (02:45:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Cannabis (Marijuana) (00:04:46) New: Huberman Lab Premium (00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety (00:10:08) Levels, Thesis, InsideTracker (00:14:01) Momentous Supplements (00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD (00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects (00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains (00:30:41) AG1 (Athletic Greens) (00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1) (00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence (00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function (00:53:07) Biological Effects of Cannabis (00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia (01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage (01:09:41) Brain Areas Affected by THC & CBD, Side Effects (01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine (01:26:41) Does Cannabis Increase Creativity? (01:35:08) Chronic Cannabis Use & Changes in Speech Patterns (01:46:46) Cannabis & Libido, Dopamine & Prolactin (01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility (02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences (02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development (02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance (02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis (02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders (02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis (02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn Title Card Photo Credit: Mike Blabac Disclaimer
Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
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Celia Morgan is a Professor of Psychopharmacology at the University of Exeter who has authored numerous publications on the potential therapeutic uses of ketamine in mental healthcare. In this episode, Celia dives deep into the neurobiology of ketamine, how it affects users, and how it differs from other, more classical psychedelics (LSD, MDMA, PCP, and psilocybin). She explains the potential promise of ketamine as a treatment for recalcitrant depression and addiction, and she details the results from her clinical trials in these areas. She discusses the importance of using ketamine in combination with psychotherapy to maximize its benefits, the potential risks associated with ketamine use, and advice for those interested in the therapeutic use of ketamine.
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All-In with Chamath, Jason, Sacks & Friedberg: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
0:00 Bestie intros!
1:36 Big tech starts making cuts, plus what this means for the broader economy and startups
31:09 Global debt numbers, Fed incompetency
54:06 RIP Coolio
1:00:30 Russia / Ukraine update
Follow the besties:
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https://linktr.ee/calacanis
https://twitter.com/DavidSacks
https://twitter.com/friedberg
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Intro Music Credit:
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Intro Video Credit:
https://twitter.com/TheZachEffect
Referenced in the show:
https://www.bloomberg.com/news/articles/2022-09-29/meta-announces-hiring-freeze-warns-employees-of-restructuring
https://www.google.com/finance/quote/META:NASDAQ
https://www.google.com/finance/quote/AAPL:NASDAQ
https://www.google.com/finance/quote/GOOG:NASDAQ
https://www.cnbc.com/2022/09/28/stanley-druckenmiller-sees-hard-landing-in-2023-with-a-possible-deeper-recession-than-many-expect.html
https://www.google.com/finance/quote/NFLX:NASDAQ
https://www.mckinsey.com/capabilities/mckinsey-digital/our-insights/if-youre-going-to-build-something-from-scratch-this-might-be-as-good-a-time-as-in-a-decade
https://www.forbes.com/sites/jonathanponciano/2021/05/11/billionaire-investor-druckenmiller-blasts-feds-radical-stimulus-policy-warns-it-risks-stock-bubble-blowing-up
https://www.cnbc.com/2022/09/28/cnbc-transcript-duquesne-family-office-chairman-ceo-stanley-druckenmiller-speaks-with-cnbcs-joe-kernen-live-during-the-cnbc-delivering-alpha-conference-today.html
https://www.xe.com/currencycharts/?from=GBP&to=USD&view=1M
https://www.bls.gov/charts/job-openings-and-labor-turnover/unemp-per-job-opening.htm
https://fred.stlouisfed.org/series/JTSJOL
https://www.wsj.com/articles/a-nation-of-quitters-great-enabling-exodus-working-age-men-parents-stimulus-covid-quit-retirement-bohemian-videogame-11664112795
https://goop.com/subscribe
https://www.reuters.com/world/putin-host-kremlin-ceremony-annexing-parts-ukraine-2022-09-29
https://www.reuters.com/world/europe/zelenskiy-says-ukraine-applying-nato-membership-2022-09-30
https://www.reuters.com/world/europe/qa-nord-stream-gas-sabotage-whos-being-blamed-why-2022-09-30
https://www.aa.com.tr/en/economy/former-polish-foreign-minister-thanks-us-for-damaging-nord-stream-pipeline/2696530
https://www.theamericanconservative.com/should-america-go-all-in-on-ukraine
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Catherine Salmon is an evolutionary psychology researcher, professor of Psychology at the University of Redlands and an author.
Women can be a mystery, sometimes even to themselves. Modern culture is making many proclamations about what women like and why they should like it, but are these new headlines accurate, or even desirable?
Expect to learn why women love erotic stories so much, whether evolutionary psychology is sexist, why Catherine did a study where people rated the attractiveness of faces which had jizz on them, why feminine men are being pushed in media but don't feature in dark romance novels, the role of commitment in female attraction and much more...
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Links: * My First Million * How To Take Over The World * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (02:25) - lessons from Hitler (10:45) - lessons from Edison (10:25) - addictive personalities (18:10) - charismatic people (26:25) - bias to action
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Neuroscientist Erik Hoel talks about why he is not an "effective altruist" with EconTalk host, Russ Roberts. Hoel argues that the utilitarianism that underlies effective altruism--a movement co-founded by Will MacAskill and Peter Singer--is a poison that inevitably leads to repugnant conclusions and thereby weakens the case for the strongest claims made by effective altruists.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern’s research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson’s disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation (00:03:18) ROKA, Eight Sleep, InsideTracker (00:07:19) Momentous Supplements (00:08:28) Neurosurgeon’s View of the Brain, Neurosurgery Specialization (00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects (00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies (00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction (00:31:11) AG1 (Athletic Greens) (00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition (00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity (00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation (00:49:49) Binge Eating Disorder & Loss of Control Eating (00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress (01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells” (01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation (01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia (01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation (01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson’s (01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression (01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation (01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions (01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts (01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training (02:09:53) Daily Habits: Sleep, Exercise, Mediation (02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn Title Card Photo Credit: Mike Blabac Disclaimer
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Few figures have shaped the way we think about business over the past 20 years more than Reid Hoffman. The co-founder of LinkedIn and former PayPal executive is also a wildly successful venture capitalist, author and podcaster, but he didn’t get to his place as a Silicon Valley giant without making plenty of crucial decisions. On this episode Hoffman discusses lessons learned from decades spent as a hands-on operator and investor, including what he knows about scaling that others miss, the three principles of decision making, how to constantly evolve your learning pattern, and why the best leaders adapt to the crisis at hand.
Hoffman is perhaps best known for co-founding the professional networking site LinkedIn, which he started in 2003 and later sold for a reported $26.2 billion to Microsoft in 2016. Prior to founding LinkedIn, Hoffman was one of the first employees at PayPal, where he served as an executive vice president. He is also a partner at the venture capital firm Greylock Partners, an investor in Airbnb, the author of a series of successful business books including Masters of Scale, and the host of the podcast of the same name.
Want to hear the entire episode with Reid Hoffman? Become a member today! Members get early access, hand-edited transcripts, member-only episodes, and so much more.
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The Rational Reminder Podcast ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
The type of assets which usually come to mind when considering investments are stocks, bonds, or cash, but what are the alternatives? And what kind of returns do alternative asset classes offer? In today’s episode, we delve into the returns which can be expected from alternative asset classes such as private equity, venture capital, angel investing, private credit, hedge funds, direct real estate, and cryptocurrencies. Hear an in-depth analysis based on empirical studies and the expertise of your hosts, Ben and Cameron, to discover whether there is any merit to alternative asset classes as investments. We unpack the extra layer of complexity associated with predicting returns on alternative assets, how to approach calculating returns, and why the associated fees are an essential consideration. We also hear details about an interesting conference Cameron recently attended and briefly recap cryptocurrencies as an investment. You’ll also hear our conversation with our 22 in 22 reading challenge guest David Senra about his reading habits, the books that most inspire him, and his advice for people who want to read more.
Key Points From This Episode:
Links From Today’s Episode:
AQR Capital Management — https://www.aqr.com/
BlackRock Asset Management — https://www.blackrock.com
Bank of America — https://www.bankofamerica.com/
‘The risk and return of venture capital’ — https://www.sciencedirect.com/science/article/pii/S0304405X04001564
‘Performance of Private Credit Funds: A First Look' — https://jai.pm-research.com/content/21/2/31.short
‘Do Hedge Funds Hedge?’ — https://jpm.pm-research.com/content/28/1/6.short
‘The Performance of Hedge Fund Performance Fees’ — https://www.nber.org/papers/w27454
‘Higher risk, lower returns: What hedge fund investors really earn’ — https://www.sciencedirect.com/science/article/abs/pii/S0304405X1100016X
‘Another Look at Private Real Estate Returns by Strategy’ — https://jpm.pm-research.com/content/45/7/95/tab-pdf-trialist
'The Characteristics and Portfolio Behavior of Bitcoin Investors: Evidence from Indirect Cryptocurrency Investments' — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3501549
‘Beliefs and the Disposition Effect’ — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3516567
‘Once Bitten, Twice Shy: The Power of Personal Experiences in Risk Taking’ — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2506627
S&P Global FinLit Survey — https://gflec.org/initiatives/sp-global-finlit-survey/
Future Proof Conference — https://futureproof.advisorcircle.com/
Invest Like the Best Podcast — https://investlikethebest.libsyn.com/
David Senra on LinkedIn — https://www.linkedin.com/in/david-senra-278843236/
David Senra on Twitter — https://twitter.com/FoundersPodcast?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor
David Senra on Facebook — https://www.facebook.com/david.senra.1
The Founders Podcast — https://founders.simplecast.com/
A Triumph of Genius — https://www.amazon.com/Triumph-Genius-Edwin-Polaroid-Patent/dp/1627227695
Cable Cowboy — https://www.amazon.com/Cable-Cowboy-Malone-Modern-Business/
Titan — https://www.amazon.com/Rare-Chernow-Titan-Life-Rockefeller/
A Man for All Markets — https://www.amazon.com/Man-All-Markets-Street-Dealer/
Against the Odds — https://www.amazon.com/Against-Odds/
Estee: A Success Story — https://www.amazon.com/Estee-Success-Story-Lauder/
Rational Reminder on iTunes — https://itunes.apple.com/ca/podcast/the-rational-reminder-podcast/id1426530582.
Rational Reminder Website — https://rationalreminder.ca/
Rational Reminder on Instagram — https://www.instagram.com/rationalreminder/?hl=en
Rational Reminder on YouTube — https://www.youtube.com/channel/
Ben Felix — https://www.pwlcapital.com/author/benjamin-felix/
Ben on Twitter — https://twitter.com/benjaminwfelix
Ben on LinkedIn — https://www.linkedin.com/in/benjaminwfelix/
Cameron Passmore — https://www.pwlcapital.com/profile/cameron-passmore/
Cameron on Twitter — https://twitter.com/CameronPassmore
Cameron on LinkedIn — https://www.linkedin.com/in/cameronpassmore/
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I explain how nicotine impacts the brain and body, including its potent ability to enhance attention, focus, and alertness, increase blood pressure and metabolism and reduce appetite. I discuss nicotine’s ability to increase the action of neurochemicals, including dopamine, norepinephrine, and acetylcholine and activate sympathetic (alertness-promoting) neural circuits. I also discuss common nicotine delivery methods, such as cigarettes, vaping, dip, and snuff, and how they each create their own unique experience and how they, but not nicotine itself, cause cancer and other adverse health effects. I also explain science-based tools to permanently quit smoking cigarettes or vaping, including peer-reviewed clinical hypnosis tools, antidepressants, and alternative nicotine replacement (patches, lozenges, gums etc.). As nicotine is one of the most widely used substances with billions of users — most of whom report wanting to quit — this episode ought to be of interest to former/current nicotine users, those who want to quit smoking or vaping and/or those interested in learning the biology behind how nicotine impacts the brain and body. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Nicotine (00:02:47) Momentous Supplements (00:03:41) Tool: Brief Daily Meditation & Focus (00:05:59) The Arrow Model of Focus, Alpha GPC & Garlic Supplements (00:10:43) Thesis, InsideTracker, ROKA (00:14:35) Nicotine Effects vs. Methods of Delivery, Acetylcholine (00:19:55) Where is Nicotine Found? Nicotinic Acetylcholine Receptors (00:25:12) Nicotine & Effects on the Brain: Appetite, Dopamine & GABA (00:30:58) AG1 (Athletic Greens) (00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting” (00:37:29) Nicotine, Norepinephrine & Alertness/Energy (00:41:10) Nicotine & Effects on Appetite & Metabolism (00:46:47) Nicotine & Effects on Body: Sympathetic Tone (00:51:29) Nicotine & Cognitive Work vs. Physical Performance (00:55:08) Nicotine Delivery Methods & Side Effects, Young People & Dependency (00:58:35) Smoking, Vaping, Dipping & Snuffing: Carcinogens & Endothelial Cells (01:02:34) Smoking, Vaping, Dipping & Snuffing: Negative Impacts on Lifespan & Health (01:09:23) How to Quit Smoking, Nicotine Cravings & Withdrawal (01:13:56) Vaping & Nicotine, Rates of Effect Onset, Dopamine, Addiction & Depression (01:25:06) Tool: Quitting Smoking & Clinical Hypnosis, Reveri (01:30:16) Bupropion (Wellbutrin) & Quitting Smoking (01:36:24) Tool: A Nicotine Replacement Schedule to Quit Smoking, Nicotine Patch/Gum (01:41:52) Tool: Biological Homeostasis & Nicotine Withdrawal, The “First Week” Strategy (01:51:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook Title Card Photo Credit: Mike Blabac Disclaimer
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Gurwinder Bhogal is a programmer and a writer.
Gurwinder is one of my favourite Twitter follows. He’s written yet another megathread exploring human nature, cognitive biases, mental models, status games, crowd behaviour and social media. It's one of the best things I've read this year, so I just had to bring him on.
Expect to learn how bad things can sometimes feel better than good things, why people die on the hill of opinions they've only just begun believing, why intelligence plus ideology is a nightmare, how comedy can be a troll's last line of defence, the biggest lesson I learned from Joe Rogan, why regret minimisation should be a priority, why authoritarians lose sight of rationality and much more...
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Extra Stuff:
Check out Gurwinder's Substack - https://gurwinder.substack.com/
Follow Gurwinder on Twitter - https://twitter.com/G_S_Bhogal
Gurwinder's new MegaThread - https://twitter.com/G_S_Bhogal/status/1545510413982474253
Adam Mastroianni's post - https://experimentalhistory.substack.com/p/underrated-ideas-in-psychology
Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/
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Honestly with Bari Weiss ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Fifteen years ago, there was a lot of talk about the obesity epidemic. In 2008, Michelle Obama started a government program called “Let’s Move!” that sought to reduce childhood obesity. You might remember the First Lady teaming up with everyone from Beyonce to Big Bird to promote exercise and better eating habits. Unfortunately, the program was largely a failure. And the obesity statistics continued to rise.
74% of Americans today are either obese or overweight. And yet, we’re no longer talking about it. The national conversation around health and weight has turned away from things like good nutrition, weight loss and the importance of physical fitness, and instead adopted phrases like “fat acceptance” and “healthy at any size.” In some circles, there’s even blanket denial that there is anything unhealthy at all about being obese.
Shaming people for being overweight is unequivocally wrong. But in our attempt to not offend, we’ve lost sight of the very real fact that there’s a problem. Americans are heavier than ever, sicker than ever, dying earlier than ever, and... it's all preventable. So today, a conversation with Dr. Casey Means, a Stanford trained physician who left the traditional medical system behind to solve the one problem that she says is going to ruin us all: bad food. Learn more about your ad choices. Visit megaphone.fm/adchoices
Behind the Tech: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
XKCD is one of our favorite webcomics - and it started out as doodles in Randall Munroe's college notebooks. Munroe describes his work as “a webcomic of romance, sarcasm, math, and language.” In this episode, he joins Kevin to talk about how he got started, where his inspiration comes from and his latest book, What If? 2: Additional Serious Scientific Answers to Absurd Hypothetical Questions. Find out why a surprising number of cartoonists are physicists by training, explore the joy of seeking answers to seemingly impossible questions, and much more!
Pod of Jake: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Brian is the Co-founder and CEO of Coinbase, a leading cryptocurrency company on a mission to increase economic freedom in the world. He is also a Co-founder of NewLimit, a biotechnology company working to radically extend human healthspan, and ResearchHub, which is aiming to accelerate the pace of scientific research. In 2018, Brian launched a nonprofit called GiveCrypto.org and signed the Giving Pledge, committing to give the majority of his wealth to charitable causes throughout his lifetime. Follow Brian on Twitter @brian_armstrong.
[2:18] - Brian's origin story
[9:33] - Reflections on his early career and how it prepared him to start Coinbase
[16:02] - Coinbase’s mission to increase economic freedom in the world, and why economic freedom is important
[23:34] - The challenges of building through crypto's hype cycles and scaling Coinbase at a rapid pace
[31:08] - An introduction to The RAPID Decision-Making Framework
[35:36] - How years of experience with remote employees helped Coinbase become a remote-first company
[45:24] - Repeatable innovation and the rationale for Coinbase’s 70/20/10 strategy for resource allocation
[54:34] - Coinbase’s contrarian decision to work with regulators from the beginning, and how it is increasingly leaning in on decentralization
[1:03:38] - Extending the human healthspan, an overview of NewLimit, and epigenetic reprogramming
[1:15:25] - Prioritizing "new media" over mainstream media
[1:21:12] - How ResearchHub can enable more open science and help build a bridge from scientific research to commercial products
Support the show by checking out my sponsors:
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Episode 356: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) with the help of Stonks.com , listen to six entrepreneurs pitch their business in hopes of getting Shaan and Sam to invest. * To watch this podcast, head over to our YouTube channel: https://youtu.be/OKI1X1qFgwg
Links: * Cherry * Pillup * Campus Ink * Terrashroom * Dealbuilder * Field Complete * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (05:35) - Luke @ Cherry (17:40) - Ankur @ Pillup (30:05) - Steven @ Campus Ink (42:45) - Jared @ Terrashroom (54:10) - Morgan @ Dealbuilder (01:04:05) - Tim @ Field Complete
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is David Anderson, PhD, a world expert in the science of sexual behavior, violent aggression, fear and other motivated states. Dr. Anderson is a Professor of Biology at the California Institute of Technology (Caltech), a member of the National Academy of Sciences and an investigator with the Howard Hughes Medical Institute (HHMI). We discuss how states of mind (and body) arise and persist and how they probably better explain human behavior than emotions per se. We also discuss the many kinds of arousal that create varying levels of pressure for certain behaviors to emerge. We discuss different types of violent aggression and how they are impacted by biological sex, gender, context, prior experience, and hormones, and the neural interconnectedness of fear, aggression and sexual behavior. We also discuss peptides and their role in social isolation-induced anxiety and aggression. Dr. Anderson also describes novel, potentially powerful therapeutics for mental health. This episode should interest anyone wanting to learn more about mental health, human emotions, sexual and/or violent behavior. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Dr. David Anderson Dr. David Anderson The Nature of the Beast Dr. David Anderson’s Lab Dr. Anderson’s publications Articles Two Different Forms of Arousal in Drosophila Are Oppositely Regulated by the Dopamine D1 Receptor Ortholog DopR via Distinct Neural Circuits Resources Mouse switching from mating behavior to aggressive behaviors upon stimulation of VMH VMH stimulation causes mouse to display aggressive behaviors toward an inanimate object (e.g., glove) Picture of Periaqueductal Gray (PAG) Timestamps (00:00:00) Dr. David Anderson, Emotions & Aggression (00:03:33) Momentous Supplements (00:04:27) Levels, Helix Sleep, LMNT (00:08:10) Emotions vs. States (00:10:36) Dimensions of States: Persistence, Intensity & Generalization (00:14:38) Arousal & Valence (00:18:11) Aggression, Optogenetics & Stimulating Aggression in Mice, VMH (00:24:42) Aggression Types: Offensive, Defensive & Predatory (00:29:20) Evolution & Development of Defensive vs. Offensive Behaviors, Fear (00:35:38) Hydraulic Pressures for States & Homeostasis (00:38:33) AG1 (Athletic Greens) (00:39:46) Hydraulic Pressure & Aggression (00:44:50) Balancing Fear & Aggression (00:48:31) Aggression & Hormones: Estrogen, Progesterone & Testosterone (00:52:33) Female Aggression, Motherhood (00:59:48) Mating & Aggressive Behaviors (01:05:10) Neurobiology of Sexual Fetishes (01:10:06) Temperature, Mating Behavior & Aggression (01:15:25) Mounting: Sexual Behavior or Dominance? (01:20:59) Females & Male-Type Mounting Behavior (01:24:40) PAG (Periaqueductal Gray) Brain Region: Pain Modulation & Fear (01:30:38) Tachykinins & Social Isolation: Anxiety, Fear & Aggression (01:43:49) Brain, Body & Emotions; Somatic Marker Hypothesis & Vagus Nerve (01:52:52) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer
Pomp Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Ed Latimore is a former heavyweight boxer, best-selling author, and chess enthusiast.
In this conversation, we discuss the crackhead work theory, Ed's recovery from alcohol addiction, why the world has gone so crazy, critical thinking, and narrative violations in recent years.
=======================
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The number one name in NFT domains and the world’s most powerful wallet are teaming up to bring something new to the crypto and Web3 world:
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==================
Bullish is a powerful new exchange for digital assets that offers deep liquidity, automated market making, and industry-leading security. Combining the innovations of DeFi with the regulated environment of traditional finance, Bullish empowers users to trade with certainty and earn passively at scale across variable market conditions, in an environment backed by multibillion-dollar liquidity contributions from the Bullish Treasury. Visit bullish.com/pomp today to learn more.
Note: Bullish is licensed by the Gibraltar Financial Services Commission. Virtual assets and related products are high risk. Consult your investment advisor and trade responsibly. Bullish is available in select locations only and not to U.S persons. Visit bullish.com/legal for important information and risk warnings.
====================
The bridge between iGaming, online sports betting, and emerging technology, such as Blockchain, NFTs, fintech, GameFi, metaverse, and AI, is loud and clear. The largest global summit of this kind is heading to Malta from November 15 to 17. Over a thousand exhibitors and 25,000 industry leaders will be there, including top executives from Draft Kings, Bet365, Socios, crypto exchanges, betting software providers, operators, gaming affiliates, and more. Log on to AIBC.WORLD and SiGMA.WORLD to see all our upcoming global summits! See you in Malta, November 15 to 17 for the leading global event in Gaming & Emerging Tech! THIS IS SiGMA!
=======================
Valour (formerly DeFi Technologies) represents what’s next in the digital economy -- providing simplified, trusted access to crypto, decentralized finance and Web 3.0 investment opportunities. Institutions and investors can gain diversified, secure, compliant, and easily tradable access to a diversified set of industry-leading equity products and protocols, through a single stock purchase on a regulated exchange.
For more information or to subscribe to receive company updates and financial information, visit our website at valour.com
=======================
If you’re trying to grow and preserve your crypto-wealth, optimizing your taxes is just as lucrative as trying to find the next hidden gem.Alto IRA can help you invest in crypto in tax-advantaged ways to help you preserve your hard earned money.
So, ready to take your investments to the next level? Diversify like the pros and trade without tax headaches. Open an Alto CryptoIRA to invest in crypto tax-free. Just go to https://altoira.com/pomp
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I provide a list of behavioral, nutritional, and supplement-based tools you can use to improve your ability to get into a focused state to do mental or physical work. I explain science-supported strategies for transitioning into focus, maintaining focus during the work bout, and exiting the focus session, which is also critical, including decompression/defocusing tools. I explain when and how to use: binaural beats, caffeine, deliberate cold exposure, the pros and cons of working in fasted vs. fed states, and supplements and foods that enhance dopamine, epinephrine (i.e., adrenaline) and acetylcholine to promote optimal focus. Also, I explain how short behavioral practices, such as meditation and visual gaze training, will benefit your ability to focus over the long term. As deep focus is crucial to significantly improve cognitive or physical performance in any realm, this episode should be useful to anyone. By the end, you’ll have an essential toolkit of science-supported, low- to zero-cost focus and concentration strategies to select from that can be tailored to your physical and mental performance needs. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Virtusan: https://virtusan.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Focus Toolkit (00:04:25) Momentous Supplements (00:05:38) Thesis, LMNT, Eight Sleep (00:09:37) The “Arrow Model” of Focus: Epinephrine, Acetylcholine & Dopamine (00:15:15) Modulation vs. Mediation, Importance of Sleep (00:18:11) Tool: Binaural Beats to Improve Concentration (00:20:54) Tool: White, Brown & Pink Noise, Transition to Focused State (00:22:55) Warm-Up for Cognitive Work, Refocusing Attention & Neuroplasticity (00:26:14) Tool: Ultradian Cycles: Warm-Up, Maintaining Focus & Deliberate Defocusing (00:31:22) How Many Daily Ultradian Cycles Can One Perform? (00:34:14) AG1 (Athletic Greens) (00:35:35) Virtusan: Mental & Physical Health Journeys (00:36:52) Tool: Fasted vs. Fed States & Focus, Prevent an Afternoon Crash, Ketosis (00:45:52) Tool: Foods to Improve Focus & Regulating Food Volume (00:47:53) Tool: Caffeine & Focused Work, Dopamine Efficacy, Alertness (00:52:55) Tool: Stress & Improved Concentration (00:55:46) Tool: Deliberate Cold Exposure & Focus, Dopamine & Epinephrine (01:00:39) Layer Focusing Tools & Design Your Own Protocols (01:01:19) Tool: Short Meditation & Improved Ability to Refocus (01:07:40) Tool: Yoga Nidra, Non-Sleep Deep Rest (NSDR) & Defocus Periods (01:12:13) Tool: Hypnosis & Focus/Deep Relaxation States (01:16:07) Optimal Time of Day to Use Specific Tools (01:16:46) Tool: Overt Visual Focus & Deliberate Gaze (01:20:42) Covert Visual Focus; Deliberate Gaze Warm-Up & Focused Work (01:24:43) Tool: Omega-3 Essential Fatty Acids (01:27:28) Tool: Creatine Monohydrate (01:29:10) Tool: Alpha-GPC & Acetylcholine, Increased Risk of Stroke? & Garlic (01:33:52) Tool: L-Tyrosine Supplements & Food (01:34:47) Combining & Choosing Focus Tools, Variability (01:36:50) ADHD Prescriptions, Training Neural Circuits, Maintenance & Reduced Dosage (01:39:19) Tool: Optimal Order Approaching Focus Tools, Prescriptions & Dependency (01:42:56) Tool: Phenylethylamine & Dopamine (01:44:50) Tool: Other Supplements to Enhance Dopamine, Epinephrine & Acetylcholine (01:46:46) Behavioral, Nutrition & Supplement Tools for Focus (01:49:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
IMPACT SHOW ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
(for EPISODES 39 - 41, visit the IMA YouTube channel)
Author of Fossil Future, Alex Epstein, shares his expertise and philosophical perspective on climate, energy and fossil fuels. Watch as Entrepreneur Peter Thiel and Epstein dive deep into the truths and arguments behind what most people may think is insane. Learn from these experts what is in the future for technology, inflation, climate and why it is okay to be optimistic even in these trying times.
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Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan is an entrepreneur and essayist, he was co-founder of Counsyl, former chief technology officer of Coinbase and former general partner at Andreessen Horowitz.
Our information diets are making us mentally fat. Whether it's fake news, mis or disinformation, state propaganda or conspiracy theories, the world is very difficult to navigate. Balaji also wants to start a new type of country, he has views on how to optimise your working day and he generates more new ideas than almost anyone. Today we get an insight into his thought process behind all of this.
Expect to learn why socialism always continues to arise across the world, how Balaji tracks all of the ideas he has in his head, why Singapore is a powerhouse of a new country, how immigration will deal with remote VR workers in India, why everyone should use a dashboard to track what's going on in their life, the key trick that the legacy media uses to manipulate you and much more...
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Extra Stuff:
Read The Network State - https://thenetworkstate.com/
Check out Balaji's website - https://balajis.com/
Follow Balaji on Twitter - https://twitter.com/balajis
Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/
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School of Greatness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Alex Hormozi is a first generation Iranian-American entrepreneur, investor, and philanthropist. In 2013, he started his first brick & mortar business, successfully scaling his business to six locations in three years. From there, he spent two years turning 32+ brick & mortar businesses around using the same model that made his privately owned locations successful. In total, He has scaled and exited 7 companies. His most notable exit was his majority sale of his licensing company for $46.2M in 2021. Concurrently in 2020, he transitioned from CEO to the owner/shareholder position in these companies and founded Acquisition.com as a way to invest his own wealth (both monetary and intellectual capital) into other businesses.
Buy his book: $100M Offers: How To Make Offers So Good People Feel Stupid Saying No
In this episode, you will learn:
For more, go to: lewishowes.com/1296
Alex's previous episode:https://link.chtbl.com/1278-pod
The Biggest Lies You've Been Told About Money, Debt & Building Wealth w/ Jaspreet Singh (Minority Mindset): https://link.chtbl.com/1257-pod
Scooter Braun On Healing Past Trauma, Building A Business Empire & Finding Peace: https://link.chtbl.com/1244-pod
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Magnus Carlsen is the highest-rated chess player in history and widely considered to be the greatest chess player of all time. Please support this podcast by checking out our sponsors: – Shopify: https://shopify.com/lex to get 14-day free trial – Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil – Fundrise: https://fundrise.com/lex – BetterHelp: https://betterhelp.com/lex to get 10% off – InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Magnus’s Twitter: https://twitter.com/MagnusCarlsen Magnus’s Instagram: https://instagram.com/magnus_carlsen Magnus’s YouTube: https://youtube.com/c/themagnuscarlsen Magnus’s Website: https://magnuscarlsen.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT
Pomp Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Texas Slim is the Founder of 'The Beef Initiative" and "Food Intelligence"
In this conversation, we talk about everything that's wrong with our current food supply today. Some of these topics include seed oils, the beef supply system, why market access has become so difficult, declining testosterone levels, the food being served to our children in school, obesity, fake meat propaganda, and how the decline in food quality matches up with the decline in U.S. Dollar over the past generation. This is a must listen if you want to get informed about providing you and your family with the proper food supply needed for a healthy life.
======================= Valour (formerly DeFi Technologies) represents what’s next in the digital economy -- providing simplified, trusted access to crypto, decentralized finance and Web 3.0 investment opportunities. Institutions and investors can gain diversified, secure, compliant, and easily tradable access to a diversified set of industry-leading equity products and protocols, through a single stock purchase on a regulated exchange. Currently listed on U.S. (OTC: DEFTF) and Canadian (NEO:DEFI) exchanges.
FTX.US is the safe, regulated way to buy and sell Bitcoin and other digital assets. Trade crypto with up to 85% lower fees than top competitors. There are no fixed minimum fees, no ACH transaction fees, and no withdrawal fees.\
If you’re trying to grow and preserve your crypto-wealth, optimizing your taxes is just as lucrative as trying to find the next hidden gem.Alto IRA can help you invest in crypto in tax-advantaged ways to help you preserve your hard earned money. Alto CryptoIRA lets you invest in more than 200 different coins and tokens with all the same tax advantages of an IRA.They make it easy to fund your Alternative IRA or CryptoIRA via your 401(k) or IRA rollover or by contributing directly from your bank account.
Crypto wallets and browser extensions are outdated, limited in features, and don’t meet the needs of today’s Web3 users. Core, the free, non-custodial browser extension built by Ava Labs, is more than just a wallet. Core is packed with features that give Avalanche users a more seamless, and secure, Web3 experience.
The number one name in NFT domains and the world’s most powerful wallet are teaming up to bring something new to the crypto and Web3 world:
Bullish is a powerful new exchange for digital assets that offers deep liquidity, automated market making, and industry-leading security. Combining the innovations of DeFi with the regulated environment of traditional finance, Bullish empowers users to trade with certainty and earn passively at scale across variable market conditions, in an environment backed by multibillion-dollar liquidity contributions from the Bullish Treasury. Visit bullish.com/pomp today to learn more.
Tales from the Crypt: A Bitcoin Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Join Marty as he sits down with Lord Miles to discuss traversing Afghanistan during a time of war. They also discuss the aftermath of visiting countries under sanctions, the global spring upon us and just how fake news coverage by the mainstream is perpetrated.
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Dr Andrew Huberman is a neuroscientist, Associate Professor at the Stanford University School of Medicine and a podcaster.
The mind and the body are intimately linked. Trying to improve your mental outcomes without thinking of your physical inputs is a losing battle, but the question of which inputs to use, and when is a huge challenge. Thankfully, Dr Huberman is one of the best communicators of high performance advice on the planet and has a lot of answers.
Expect to learn the neuroscience of getting over your ex, how David Goggins trained himself to lean into fear, whether dopamine detoxing really works, the most important things to avoid doing during your morning routine, just how worried we should be about men's testosterone levels dropping, what everyone can learn about endurance from Lex Fridman, why Andrew doesn't show his tattoos and much more...
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis’ research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Erich Jarvis & Vocal Communication (00:03:43) Momentous Supplements (00:04:36) InsideTracker, ROKA, LMNT (00:08:01) Speech vs. Language, Is There a Difference? (00:10:55) Animal Communication, Hand Gestures & Language (00:15:25) Vocalization & Innate Language, Evolution of Modern Language (00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders (00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization (00:31:34) Genes for Speech & Language (00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes (00:41:39) AG1 (Athletic Greens) (00:42:52) Semantic vs. Effective Communication, Emotion, Singing (00:47:32) Singing, Link Between Dancing & Vocal Learning (00:52:55) Motor Theory of Vocal Learning, Dance (00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions (01:04:11) Facial Expressions & Language, Innate Expressions (01:09:35) Reading & Writing (01:15:13) Writing by Hand vs. Typing, Thoughts & Writing (01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations (01:26:58) Modern Language Evolution: Texting, Social Media & the Future (01:36:26) Movement: The Link to Cognitive Growth (01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation (01:48:24) Evolution of Skin & Fur Color (01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer
Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.
In this episode, we discuss:
Watch this episode on YouTube
Show notes are available by clicking here
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Links: * MrBeast * Hasan Minhaj * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (02:45) - What Hassan and MrBeast think of each other (03:25) - How do you measure success? (12:15) - How do you run your company? (19:20) - Doing good while getting attention (22:25) - Fitting in vs standing out (25:55) - What are you trying to figure out?
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto * #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Peter Zeihan is a geopolitical analyst, author and a speaker.
The world is changing faster than ever, and a lot of the countries, dynamics, peace treaties and structures we're familiar with may be about to come to an end. Peter's job consists of him analysing data from geography, demographics, and global politics to understand economic trends and make predictions. And if his predictions are correct, the next 50 years are going to look incredibly different.
Expect to learn why China will lose half of it's population by 2050, why globalisation is coming to an end even though we're more connected than ever, why population demographics are one of the most important factors in determining the future, whether automation will help or hinder us, whether food shortages are actually something to panic about and much more...
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The Fantastic History Of Food: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Even the most famous and lauded among us still have a few tasty secrets up their sleeves, and today we’re going to dive into this fascinating side of one of modern cookings most famous gourmands: Julia Child.
Thank you to Athletic Greens for being a sponsor for this episode.
To make it easy, Athletic Greens will give you a FREE 1 year supply of immune-supporting Vitamin D AND 5 FREE travel packs with your first purchase. All you have to do is visit www.athleticgreens.com/EMERGING to take ownership of your health and pick up the ultimate daily nutritional insurance!
Please support me on Patreon: https://www.patreon.com/foodhistorypod
Find transcripts and sources on the website: www.foodhistorypodcast.com
References:
https://allthatsinteresting.com/julia-child-spy
https://www.cia.gov/stories/story/julia-child-and-the-oss-recipe-for-shark-repellent/
https://www.cia.gov/stories/story/julia-child-cooking-up-spy-ops-for-oss/
https://www.washingtonpost.com/history/2022/05/02/julia-child-hbo-oss-sharks/
https://www.history.com/news/julia-child-oss-spy-wwii-shark-repellent
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone. Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Effects of Alcohol Consumption (00:02:25) Momentous Supplements (00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration (00:06:52) Levels, Eight Sleep, ROKA (00:10:46) Historical Context & Uses of Alcohol (00:13:28) Alcohol Metabolism, “Empty Calories” (00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation (00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility (00:27:55) Food & Alcohol Absorption (00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts (00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress (00:44:53) AG1 (Athletic Greens) (00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young (00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut (00:59:46) Tool: Improving/Replenishing Gut Microbiome (01:02:44) Reducing Alcohol Consumption & Stress (01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache (01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure (01:17:16) Hangover Recovery, Dehydration & Electrolytes (01:20:45) Types of Alcohol & Hangover Severity, Congeners (01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance (01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol (01:35:42) Alcohol & Brain Thickness (01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk (01:44:31) Mitigating Cancer Risk, Folate, B Vitamins (01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome (01:50:58) Hormones: Testosterone & Estrogen Balance (01:55:09) Negative Effects of Alcohol Consumption (01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Recently I had the pleasure of hosting two live events, one in Seattle, WA and one in Portland, OR. These events were part of a lecture series called The Brain Body Contract. My favorite part of each evening was the question & answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event in Seattle, WA. Attend The Brain Body Contract Live Events Los Angeles, CA: October 16, 2022 New York, NY: November 9, 2022 https://hubermanlab.com/tour Presale password: huberman Thank you to our sponsors Momentous: https://www.livemomentous.com/huberman InsideTracker: https://insidetracker.com/huberman Timestamps (00:00:00) The Brain Body Contract Q&A (00:01:07) Momentous Supplements, InsideTracker (00:01:35) Upcoming Live Events: Los Angeles & New York (00:02:16) What Is Your Most-Used Protocol? (00:04:12) Should You Vary Wake-Up Time Seasonally? (00:06:05) Why Is My Drive Depleted Upon Waking-Up? (00:08:42) What Are Your Favorite/Most Impactful Books? (00:12:08) What Excites You About the Future of Mental Health Treatment? (00:17:25) What Is the Biggest Area Tor Performance Enhancement? (00:21:44) Can You Still Do a Kickflip? (00:22:32) Tips on How to Improve Memory (00:24:54) How Do You Manage Social Media Addiction? (00:27:43) Were You Nervous Tonight/ How Did You Prepare? (00:29:10) Is Learning from Failure Equal to Learning from Success? (00:32:23) When Are You Going to Start Training Jiu-Jitsu? (00:33:28) Discuss the Supplements You Take (00:36:29) Advice or Protocols to Improve Learning & Retention (00:38:42) What Exciting Research/Work are You Doing? (00:40:22) How Does Dopamine Factor into Neuroplasticity? (00:43:12) What Advice Do You Have for Future Scientists? (00:46:47) Is Age 66 Too Old for Neuroplasticity & Learning? (00:48:00) How Do You Read Research Papers? (00:49:40) What is Your Favorite Condiment? (00:50:10) Most Important Takeaway from Your ADHD Research? (00:52:58) What Future Episodes Are in the Pipeline? Title Card Photo Credit: Mike Blabac Disclaimer
Invest Like the Best: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest today is Katherine Boyle, a general partner at Andreessen Horowitz. Katherine started her career as a reporter for The Washington Post before moving into VC at General Catalyst. She now leads a practice at a16z called American Dynamism, investing in companies that are solving critical issues in areas like defense, housing, and education. In the past year, I've spoken to Marc Andreessen, Josh Wolfe, and a number of founders about this need to build societally important businesses so I was excited to explore the topic in even more detail today. Please enjoy my conversation with Katherine Boyle.
For the full show notes, transcript, and links to mentioned content, check out the episode page here.
The content here is for informational purposes only and should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security and is not directed at any investors or potential investors in any a16z fund. For more details, please see a16z.com/disclosures.
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This episode is brought to you by Tegus. Tegus streamlines the investment research process so you can get up to speed and find answers to critical questions on companies faster and more efficiently. The Tegus platform surfaces the hard-to-get qualitative insights, gives instant access to critical public financial data through BamSEC, and helps you set up customized expert calls. It’s all done on a single, modern SaaS platform that offers 360-degree insight into any public or private company. As a listener, you can take Tegus for a free test drive by visiting tegus.co/patrick. And until 2023 every Tegus license comes with complimentary access to BamSec by Tegus.
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Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
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Show Notes
[00:02:42] - [First question] - The origin and overview of the term American Dynamism
[00:05:01] - Why the shift to a move slow and make sure nothing breaks mentality
[00:07:31] - What about the American system today feels broken and stale
[00:09:48] - Becoming a journalist at The Washington Post
[00:11:35] - Describing the power landscape of media as it exists today
[00:12:28] - Major categories of American Dynamism that matter most
[00:14:29] - What matters more or less to her as an investor in these categories
[00:17:31] - Whether or not there’s anything fundamentally broken about our government
[00:19:36] - The Systems Bible; What excites her about aerospace and defense and what creates opportunity and demand in these sectors
[00:22:44] - Explanation of what it means when the factory is the product
[00:23:47] - How much is flowing into aerospace and defense currently
[00:26:01] - An overview of how lobbying works and who does it and why
[00:29:07] - Whether or not she considers these sectors from a bottom up perspective as in investor
[00:30:32] - What other categories she feels pulled towards
[00:33:09] - The biggest problems that currently exist in the K-12 school system
[00:35:34] - Thoughts on how states are competing citizens and how it plays into American Dynamism
[00:37:34] - The role immigration will play in range of outcomes in these main categories
[00:39:32] - Key takeaways about housing in light of American Dynamism
[00:42:09] - Her interpretation of the chart that shows inflation in categories over time
[00:44:40] - How different the investing dynamics are in all of these categories and thoughts on valuation in this world
[00:47:56] - Whether or not expected returns and risk profiles are different in this area
[00:48:36] - The importance of effective a founder’s storytelling, knowledge and customer empathy
[00:49:55] - Overview of the anatomy of a great story
[00:51:30] - The story she tells founders at this stage so establish a partnership
[00:52:46] - The kindest thing that anyone has ever done for her
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on your overall health and daytime functioning, brain, hormones and immune system. I teach you how to effectively harness light (and darkness), temperature, food, exercise, caffeine, supplements, and digital devices in order to fall asleep faster, stay deeply asleep longer and overall, and achieve better quality sleep. I also describe how these tools can be modified to recover quickly from a poor night’s sleep, jet lag or bouts of shift work. Given that sleep is the foundation of all mental health, physical health and performance, this episode should benefit everyone as it provides an essential toolkit of science-supported, low- to zero-cost strategies that can be tailored to optimize your sleep routine. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Tools to Optimize Sleep (00:03:02) Momentous Supplements (00:04:16) InsideTracker, Eight Sleep, LMNT (00:08:24) Factors to Control Circadian Rhythm & Sleep (00:15:10) Morning Tool: Morning Sunlight Viewing, Cortisol (00:20:44) Morning Sunlight: Circadian Rhythm, Artificial Lights, Cloudy Days (00:26:18) Evaluating Light in Environment, Compensating for Missed Morning Light (00:29:26) AG1 (Athletic Greens) (00:30:46) Morning Tools: Temperature & Deliberate Cold Exposure, Exercise (00:34:58) Timing Caffeine, “Afternoon Crash,” Exercise (00:40:08) Timing Eating, Alertness & Circadian Rhythm (00:45:20) 3 Daily Critical Periods (00:46:49) Afternoons: Naps, Deep Relaxation (NSDR, Self-Hypnosis), Exercise & Body Temperature, Caffeine (00:51:59) Afternoon Tools: Viewing Sunlight in Late Afternoon, Evening Light (00:56:45) Evening/Night Tools: Overhead Artificial Lights, Light Sensitivity (01:04:40) Evening Tools: Hot Bath/Sauna, Temperature & Sleeping Environment (01:09:40) Alcohol, THC & Reduced Sleep Quality; CBD, Anxiety & Falling Asleep (01:11:45) Sleep Supplements: Magnesium Threonate, Apigenin & Theanine (01:16:34) Melatonin Supplementation (Caution) (01:17:44) Additional Sleep Supplements: GABA, Glycine, Myo-Inositol & Anxiety (01:20:08) Falling Back Asleep: Reveri App, NSDR, Yoga Nidra (01:22:55) Staying Asleep: Eye Masks, Ear Plugs, Elevating Feet (01:24:58) Tool: Sleep Apnea & Nasal Breathing (01:28:20) Sleep Schedule Consistency, Weekends, Compensatory Sleep & Caffeine (01:31:14) Tools: Temperature Minimum & Jet Lag, Shift Work & Red Lights (01:37:38) Behavioral Tools for 3 Daily Critical Periods (01:39:26) Zero-Cost Support, YouTube Feedback, Huberman Lab Clips, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Sheel Mohnot is a Co-Founder and General Partner @ Better Tomorrow Ventures, a $225M fund that leads rounds in pre-seed and seed-stage fintech companies globally. Sheel and Jake (his co-founder) invested for many years together before founding BTV and wrote checks into Mercury, Flexport, Ramp, and Hippo Insurance to name a few. As for Sheel, before BTV he ran 500 Fintech for close to 7 years, and before that was a founder, founding two companies, both of which were acquired. If that was not enough, Sheel is also a master at measuring the width of swimming pools and making cameo appearances in music videos with Justin Bieber.
In Todays Episode with Sheel Mohnot We Discuss: 1.) Entry into Venture:
2.) The Power Law:
3.) Venture Capital has Never Been Less Collaborative:
4.) The Biggest Wins and Misses:
5.) Emerging and Frontier Markets:
Items Mentioned in Today's Episode: Sheel's Favourite Book: Enders Game
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Assessing Health Status & Improving Vitality (00:02:51) Momentous Supplements (00:03:46) Thesis, InsideTracker, Helix Sleep (00:07:29) Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease” (00:11:51) Healthspan: Functional Testing, Cognitive & Emotional States (00:13:59) Blood Testing: Best Frequency (00:16:01) DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis (00:22:33) Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids (00:29:24) Osteopenia & Osteoporosis Diagnosis, Strength Training (00:31:03) AG1 (Athletic Greens) (00:32:16) Back-casting: Defining Your “Marginal Decade” (00:38:31) All-Cause Mortality: Smoking, Strength, VO2 max (00:44:43) Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals (00:49:24) Importance of Exercise, Brain Health, MET hours (00:55:23) Nicotine & Cognitive Focus (01:03:12) Menstruation, PMS & Menopause (01:10:10) Hormone Replacement Therapy, Menopause & Breast Cancer Risk (01:22:06) Estrogen, Progesterone & Testosterone Therapies in Women (01:26:35) Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin (01:37:23) Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG (01:47:46) Fadogia Agrestis, Supplements, Rapamycin (01:52:06) Testosterone Replacement Therapy & Fertility (01:59:26) Total Testosterone vs. Free Testosterone (02:02:51) Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B (02:17:42) Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions (02:25:15) Cardiovascular Disease, Age & Disease Risk (02:28:53) Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation (02:37:40) Metabolomics & Exercise (02:40:44) GLP-1 & Weight Loss (02:47:06) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer
Genius Life: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Max Lugavere is a science journalist, host of The Genius Life podcast, and New York Times best-selling author. His latest book, Genius Kitchen: Over 100 Easy and Delicious Recipes to Make Your Brain Sharp, Body Strong, and Taste Buds Happy, is out now.
Pomp Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Mike Solana is a Vice President of Founders Fund, the ring leader of Hereticon, and Editor-In-Chief At Pirate Wires.
In this conversation, we talk about everything: politics as theater, if the truth exists anymore, why science is no longer science, the changing definitions in society, AOC, Ron DeSantis, Donald Trump, Joe Biden, Gavin Newsom, conspiracy theories such as lab leak & Hunter Biden, and more! Nothing is off limits in this conversation.
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Either sign up for a free blockchain.wallet or visit Unstoppabledomains.com to buy your domain today.
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Chase Jarvis Live Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Steven Pressfield is a bestselling author of a number of both fiction and nonfiction books, such as The Legend of Bagger Vance and Tides of War. He also has bestselling classics on creativity, such as the War of Art and Turning Pro.
I have read and recommended many of Steven’s books to my audience and fellow creatives over the years and am indebted to him, particularly for his work in The War of Art. Our recent conversation on my show focused on his most recent book, Put Your Ass Where Your Heart Wants to Be, as well as a sneak preview into another book that will be released later this year!
Enjoy!
Highlights from the Show:
[00:00] Intro
[02:03] The War of Art
[03:30] Big “R” Resistance
[07:25] Turning Pro
[09:43] Put Your Ass Where Your Heart Wants to Be
[17:46] The Cost of Not Pursuing Your Dreams
[19:01] Talent is Bullshit
[27:00] You want to do good work? Show me all your garbage
[32:22] Creative Process of Steven Pressfield
[42:58] The Risking Thing is Where the Best Stuff Lies
[56:50] The Hero’s Journey
Today's episode is brought to you by CreativeLive. CreativeLive is the world's largest hub for online creative education in photo/video, art/design, music/audio, craft/maker and the ability to make a living in any of those disciplines. They are high quality, highly curated classes taught by the world’s top experts -- Pulitzer, Oscar, Grammy Award winners, New York Times best selling authors and the best entrepreneurs of our times.
The Reason Interview With Nick Gillespie ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
The Monty Python legend says political correctness poisons thinking in all areas of human activity.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Dr. Emily Balcetis, PhD, Professor of Psychology at New York University (NYU). Dr. Balcetis’ research focuses on how our perception of the world, particularly our visual perceptions, influences our level and persistence of motivation, how we conceptualize goals, actual goal achievement, and our emotional state as we pursue goals. Dr. Balcetis explains how to best visualize and overcome challenges in pursuit of larger, complex goals. We also discuss the science of how to define goals and intermediate milestones, overcome obstacles, and effectively track progress. This episode highlights science-based, immediately actionable tools that anyone can use to set and achieve physical and/or cognitive goals more effectively. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Levels: https://levels.link/huberman ROKA: https://roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Emily Balcetis, Visualization of Goals & Motivation (00:03:24) Momentous Supplements (00:04:38) Thesis, Levels, ROKA (00:08:08) Vision & Motivation (00:11:37) Tool: Narrowing Visual Focus & Improving Exercise (00:21:39) Adjusting Visual Attention & Perceived Fatigue (00:25:14) Tool: Visual Focus “Spotlight” (00:27:57) Tool: Goal Gradient Hypothesis, Visual Spotlight to Increase Effort (00:33:38) AG1 (Athletic Greens) (00:35:00) Defining Goals vs. Accomplishing Goals, Dream Boards & Goal Lists (00:41:28) Tool: How to Setting Better Goals & Identify Obstacles (00:46:38) Vision is Unique, Challenging the Visual System, Realistic Goals & Micro-Goals (00:57:12) Do Fit People View the World Differently?, States of Body & Visual Experiences (01:05:54) Caffeine, Stimulants, Visual Windows & Motivation (01:10:13) Tools: Goal Setting & Cognitive (Non-Physical) Goals, Data Collection (01:21:54) Year in Review & Memory (01:26:32) Visual Tools & Mental Health, Depression & Visual Priming (01:31:33) Focusing Attention & Increasing Visual Detail/Resolution (01:36:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter, Instagram, Twitter, Momentous Supplements Title Card Photo Credit: Mike Blabac Disclaimer
Pomp Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode is a conversation with Andrew Tate, the most viral person on the internet right now.
This conversation was recorded back in May of 2021. In this discussion, Andrew shares his unique and often controversial opinions about society. Some I agree with, some I do not. What's clear is that Andrew has mastered the internet and the social media algorithm, and I thought it would be important to share his opinions as part of the broader conversation in a free speech society.
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Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Brian Armstrong is the CEO of Coinbase. Please support this podcast by checking out our sponsors: – Audible: https://audible.com/lex – Skiff: https://skiff.org/lex – BiOptimizers: http://www.magbreakthrough.com/lex to get 10% off – Fundrise: https://fundrise.com/lex – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil EPISODE LINKS: Brian’s Twitter: https://twitter.com/brian_armstrong Brian’s Instagram: https://www.instagram.com/brian_armstrong Coinbase’s Website: https://www.coinbase.com ResearchHub: https://www.researchhub.com NewLimit: https://www.newlimit.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Canadian businessman and billionaire investor Andrew Wilkinson has made a successful career out of channeling his entrepreneurial spirit, but he knows that sometimes that energy can be a double-edged sword. On this episode, Wilkinson goes in-depth on the lessons learned from a career that’s seen him build a business empire of more than 40 companies, but also why he’s had to re-calibrate his personal goals after struggling to find happiness in the summer of 2021. He also discusses mimetic desire, building a business in a small Canadian market, competing with venture-backed companies, strategies for hiring CEOs, the mistakes that have cost him millions of dollars, and so much more. Wilkinson is the co-founder of Tiny Capital, which boasts an enterprise value of more than $1 billion and owns 35 different companies including AeroPress, MetaLab and Dribble. He is also the co-founder and chairman of WeCommerce, a holding company that starts, buys, and invests in the world’s top Shopify businesses. He is based in Victoria, British Columbia. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/
Follow Shane on Twitter at: https://twitter.com/ShaneAParrish
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I explain the biology, symptoms, causes and types of bipolar disorder (sometimes called bipolar depression). I discuss neuroplasticity and how the brain normally regulates mood, energy, and perceptions; then, I contrast that with the biology of bipolar disorder, which is characterized by extremes of energy and mood, e.g., mania and depression. I outline the mechanisms through which bipolar disorder manifests in the brain, including deficits of interoception and reduced connections between the parietal and limbic systems. I also outline how treatment options (such as lithium) work in part through homeostatic plasticity.’ I discuss not only lithium but also the treatment of bipolar with ketamine, different talk therapies, electroconvulsive therapy, transcranial magnetic stimulation, and nutraceuticals, including Omega-3 and Inositol supplementation. This episode should interest anyone who has or knows someone with bipolar disorder and, more broadly, those interested in how the brain works to create a balance between thoughts, energy levels, focus, and mood. Thank you to our sponsors InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com/huberman Blinkist: https://www.blinkist.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Bipolar Disorder (00:02:23) Momentous Supplements (00:03:42) Tool: Appetite Suppression & GLP-1, Parallel Pathways, Yerba Mate (00:10:23) InsideTracker, ROKA, Blinkist (00:14:24) Prevalence & Severity of Bipolar Disorder (00:16:30) Bipolar Disorder I, Diagnostic Criteria of Mania (00:28:58) Bipolar Disorder II, Individual Variability (00:33:07) Bipolar I vs. Bipolar II: Manic, Depressive & Symptom-Free States (00:38:20) Consequences of Bipolar Disorder, Heritability (00:46:53) Bipolar Disorder vs. Borderline Personality Disorder (00:51:51) Mania & Depression, Negative Impacts (00:53:06) History of Lithium Treatment (01:02:44) Lithium Treatment & Side-Effects (01:05:05) Effects of Lithium: BDNF, Anti-inflammatory & Neuroprotection (01:10:10) Neural Circuits of Bipolar Disorder, Interoception, Hyper- vs. Hypoactivity (01:17:11) Neural States & Mania, Parietal Lobe & Limbic System (01:22:58) Homeostatic Plasticity, Synaptic Scaling, Lithium & Ketamine (01:36:00) Talk Therapies: Cognitive Behavioral Therapy, Family-Focused Therapy, Interpersonal & Social Rhythm Therapy (01:43:18) Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (rTMS) (01:48:01) Psylocibin, Cannabis (01:51:50) Lifestyle Support, Supplements: Inositol & Omega-3 Fatty Acids (02:03:31) Omega-3s, Membrane Fluidity & Neuroplasticity (02:06:44) Mania, Creativity & Occupations (02:15:33) Bipolar Disorder: Diagnosis, Neural Circuits & Treatment (02:17:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Bitcoin Magazine Podcast ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Michael Saylor (@Saylor) and Aleks Svetski (@GhostofSvetski) have a long-form conversation about the implications of Bitcoin and its effects on the world we live in today.
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Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Indian entrepreneur and venture capitalist Kunal Shah calls on his decades of entrepreneurial experience to discuss what he’s learned about what motivates people, and how observing trends have made him a runaway success in business. Shah also discusses the cultural differences between India and the West, the lessons he learned growing up in the family business, why he dropped out of an MBA program, strategies for decision-making, and so much more. Shah is the founder and CEO of CRED, an Indian fintech company that serves as a reward-based credit card payments app. Shah also currently sits on the board of a variety of Indian companies and has served as an investor in dozens of companies since 2016. --
Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/
Follow Shane on Twitter at: https://twitter.com/ShaneAParrish
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Anthony Pompliano is an entrepreneur, investor, writer, and podcaster on topics of decentralized finance. Please support this podcast by checking out our sponsors: – Theragun: https://theragun.com/lex to get 30 day trial – Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Indeed: https://indeed.com/fridman to get $75 credit EPISODE LINKS: Anthony’s Twitter: https://twitter.com/APompliano Anthony’s YouTube: https://www.youtube.com/c/AnthonyPompliano Anthony’s Website: https://anthonypompliano.com/ Pomp Letter: https://pomp.substack.com/ Pomp Podcast: https://anthonypompliano.com/podcast/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT &
What Bitcoin Did: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
“I think this decade is going to be transformative, but we’re still too early to say exactly where this ends up or how quickly this goes.”
— Lyn Alden
SHOW DESCRIPTION
Lyn Alden is a macroeconomist and investment strategist. In this interview, we discuss the rise and role of Central Banks: their intermittent role in the US’s history, the piecemeal erosion of a gold standard, the new era of easy money, and whether Bitcoin could replace Central Banking.
Central Banks have played such a dominant role in our societies it’s easy to assume that they are required institutions within modern governmental systems. The idea that the market can determine a monetary policy and the price for money is well outside of the Overton window.
Yet, for long periods in the industrialised era modern civilised societies have functioned, developed and prospered without such institutions. Further, there is ample evidence that central banks are now far from being a steadying force that brings stability to economies.
For around 100 years, the international monetary system was pegged to gold; albeit there were debasements, new controls, and periodic abandonments during this period. Then in 1971, the monetary system was taken off any remnants of a gold standard. Its constraints on US fiscal policy had become too burdensome. It led to the development of fiat currencies and a period of easy money.
Governments have become increasingly dependent upon Central Banks in creating new money to assist with economic shocks: following the global financial crisis the production of dollars markedly increased. But these events were dwarfed by the injection of new money during the pandemic. Inflation is now catching up, but at a time when economies are stagnating.
Cycles of debt accumulation always come to an end. Without careful political judgement, coordination and luck, the resolution of unsustainable debt at the global level can lead to domestic and international conflict. So, we’re entering a transformative decade.
The question is whether Bitcoin, the strongest form of money ever invented, can enable society to navigate through this unwinding of the long-term debt cycle? Additionally, can it enable the market to again determine the price of money?
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Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
To celebrate 500 episodes on Modern Wisdom, I broke down some of my favourite lessons, insights and quotes from the last 4 and a half years.
Expect to learn why having no role models can be an advantage, how discipline eats motivation for breakfast, why you should be training for the difficult, why success in pursuit of happiness can be self-defeating, why fame makes you weak, how an obsession with productivity is just immortality by another name, what I learned about negativity biases from Margaret Thatcher, the importance of letting go of successful habits for new ones and much more...
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My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk to Co-Founder & CTO of HubSpot, Dharmesh Shah (@dharmesh), about why a bad economy is a good time to start a business, creating an alternative to Wordle, and the trillion dollar Venn diagram of success. Also, want $5,000? Check out the My First Million Clips contest.
Links: * HubSpot * Why to Start a Startup in a Bad Economy article * WordPlay * Maven writing course * Shaan tweet about starting the next Pixar * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (02:10) - Why renting is better than owning (25:20) - Framework for three types of employees (35:05) - Why Dharmesh built WordPlay (01:07:55) - Driving value through an intersection of skills (Trillion dollar Venn diagram) (01:12:10) - Why Shaan is starting the next Pixar
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
• #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Honestly with Bari Weiss ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
There are nearly 4000 universities in the U.S.. Many of them have billions of dollars in endowments and histories that go back to well before the country's founding. So you'd be forgiven for thinking that it would be a bit ridiculous to try and compete with those Goliaths.
But that's exactly what the new University of Austin or UATX is doing. The premise, of course, is simple, and it goes like this. While the brand name schools have the money, they no longer have the mission. They have fundamentally abandoned the point of the university, which is the pursuit of truth. The good people at UATX, where I'm proud to be on the board, are not waiting for the broken status quo to change. They're not sitting around criticizing or whining. They are doing.
Just a few weeks ago, UTAX opened its doors to its first students at its inaugural summer school. I was blown away by the students that I met there, and I was honored to lecture alongside teachers like Neil Ferguson, Kathleen Stock, Ayaan Hirsi Ali, Rob Henderson and Thomas Chatterton Williams. And today I wanted to share with all of you the talk that I gave at the old parkland in Dallas to that first class of students. It's about the broken moment that we're in as a culture and a country, but more it's about what I think is required of us to meet this moment. Learn more about your ad choices. Visit megaphone.fm/adchoices
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world’s leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One’s Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I explain the biological roles of the four major neuromodulators—dopamine, epinephrine (aka adrenaline), serotonin, and acetylcholine—and describe how these neuromodulators impact a wide variety of mental states and behaviors, including focus, creativity, motivation, drive, learning, alertness, mood, relationships, and feelings of well-being. Then, with that foundational understanding in mind, I describe a potent toolkit of science-supported behavioral, nutrition, and supplementation tools that can be used to increase baseline levels of individual neuromodulators and that can be modified for specific goals. This episode summarizes low-or-no-cost, actionable, science-based tools that can benefit anyone in order to enhance their levels of brain chemicals and improve mental health, physical health, and performance. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Optimizing Neurochemicals to Improve Health (00:03:40) Momentous Supplements (00:05:30) Sleep & Maintaining Healthy Metabolism (00:09:52) Tools: How to Wake Up Earlier, Night Owls (00:19:32) AG1 (Athletic Greens), Thesis, InsideTracker (00:22:05) Nervous System Overview (00:31:32) How Neuromodulators Work (00:34:24) Baseline Neuromodulator Levels, 3 Daily Phases (00:42:15) Hormones Modulate Neuromodulators (00:52:12) The 4 Major Types of Neuromodulators (01:01:45) Tool Kit 1: Increase Baseline Dopamine & Focus (01:08:52) Tyrosine-rich Foods & Dopamine (01:10:59) Dopamine Supplementation: Mucuna Pruriens, L-tyrosine & Phenylethylamine (01:16:00) Deliberate Cold Exposure & Dopamine (01:21:12) Tool Kit 2: Additional Tips to Increase Dopamine (01:26:10) Tool Kit 3: Increase Epinephrine (Adrenaline) & Alertness (01:34:34) Tool Kit 4: Increase Acetylcholine & Attention/Learning; Choline-rich Foods (01:37:29) Acetylcholine Supplements: Nicotine, Alpha GPC, Huperzine (01:44:47) Tool Kit 5: Behavior to Increase Focus & Acetylcholine (01:46:56) Tool Kit 6: Behavior to Increase Serotonin & Feelings of Well-being (01:50:51) Tools: Tryptophan-Rich Foods & Serotonin (01:53:31) Tools: Serotonin Supplements: Cissus Quadrangularis, 5-HTP, Myo-inositol (02:02:14) Use the Neurochemical Toolkit to Meet Individual Goals (02:06:44) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
The Realignment ✓
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Marc Andreessen, cofounder and general partner at Andreessen Horowitz, cofounder of Netscape, and co-creator of the influential Mosaic web browser joins The Realignment to discuss how the second industrial revolution (1880s-1920s) shapes his view of America today, the consequences of the shift from a high to low institutional trust society, the response to Web3 skeptics, how crashes shape the tech industry, and why it's "time to build."
Jocko Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
One day you're a team member, and the next day you are the supervisor. How do you handle that position?
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My guest this episode is Jeff Cavaliere, MSPT CSCS, a world-class physical therapist and Certified Strength & Conditioning Specialist. Jeff has coached athletes ranging from novice to professional and has taught science-based physical training protocols to tens of millions of everyday people via his enormously clear and actionable online programs. Jeff is a true expert on proper resistance and cardiovascular training, injury prevention and rehabilitation and has extensive knowledge on proper form, posture, nutrition and supplementation. We discuss how to best design and optimize a physical training program to achieve your specific goals. We also discuss how to build and leverage mental focus during workouts, when and how to stretch, pain management and enhancing workout recovery and sleep, and how to personalize your training and nutrition program over time. Jeff’s knowledge and science-based approach ought to benefit everyone in reaching their desired fitness, aesthetic and overall health goals. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Eight Sleep: https://www.eightsleep.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Jeff Cavaliere, Physical Training (00:03:27) Momentous Supplements, AG1 (Athletic Greens), Eight Sleep, ROKA (00:08:38) Tool: A Fitness Plan for General Health (00:13:27) Tool: Optimizing Body Part Training Splits (00:20:12) Two-a-Day Training (00:22:33) Cardiovascular Conditioning, High-Intensity Interval Training (HIIT) & Skills (00:28:24) Tool: Mind-Muscle Connection, The Cavaliere Cramp Contraction Test (00:35:05) “Muscularity” & Resting Tone (00:41:31) Tool: Muscle Recovery & Soreness, Grip Strength (00:50:39) Sleep & Sleep Position (00:57:24) Active (Dynamic) vs. Passive Stretching, Timing & Healing Muscle (01:07:23) Tool: Jumping Rope (01:12:56) Internal & External Rotation, Upright Row vs. High Pull (01:24:27) Back Pain Relief & Medial Glutes, Body Pain & Origins (01:37:39) Tool: Properly Holding Weights & Deepening Grip (01:43:54) Tool: Physical Recovery, Heat & Cold Exposure (01:47:19) Tool: Record Keeping for Training Performance & Rest Time (01:51:47) Nutrition Principles & Consistency, Processed Foods & Sugar (02:00:15) Tool: “Plate Eating”: Protein, Fibrous & Starchy Carbohydrates (02:11:25) Training in Men vs. Women, Training for Kids & Adolescents (02:18:05) Tool: Pre- and Post-Training Nutrition (02:26:30) Intensity & Training Consistency (02:29:53) AthleanX, Jesse Laico & Fitness Journeys (02:38:27) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Beginner's Mind ✓
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These days many sources are highlighting the shocking scale of the global mental health crisis and how this affects approx—a staggering one billion people worldwide - over one-seventh of the global population.
“Unfortunately, as harrowing and monstrous this number is”, the investor Christian Angermayer wrote in a blog post, “it is my belief this is a gross UNDER-estimate.”
Ultimately, the number of people needing mental health support is arguably all 100% of the world's population.
I invited Dr. Jonathan Sporn, CEO of Gilgamesh Pharmaceutical, to gain more insights into the unmet medical need in mental health and the promising novel psychedelic drug development sector
Jonathan Sporn MD is a Board Certified Psychiatrist, assistant professor at Columbia University, and CEO of Gilgamesh Pharmaceuticals, based in NYC, which is developing novel psychedelic-related or inspired medicines to treat mental illness.
Topics we discuss in this episode:
➡️ Global Mental Health Situation
➡️ The History of Psychedelic Drug Development
➡️ Investors in this promising area
➡️ The Background Story to the foundation of Gilgamesh Pharmaceutical and
➡️ And the Different Ingredients Needed to Structure a Novel Game-Changing Drug Development Company
Connect with Jonathan Sporn on Linkedin
Youtube Video
🕒 Timestamps:
(00:00) Introduction to Topic, Speaker, and Company
(04:00) Life in New York in 2022
(07:15) The Global Mental Health Pandemic
(10:39) Mass Shootings in the United States as a result of the Mental health Situation
(14:05) Why is it Necessary to Develop Novel Drugs to Fight Mental Health Issues in Society
(19:00) The History of Drug Development for Mental Health Patients
(24:00) How Effective Are Psychedelic Drugs to Tackle Mental Health Questions?
(25:05) Psychedelic Drugs in Pop Culture
(26:40) What Inspired Jonathan Sporn to Dedicate His Professional Life to Advance R&D in Psychedelic Drugs
(29:30) Psychedelic Drugs Help to Observe Own Behaviour
(32:30) Root Causes of Mood Disorders like Maniac Depression, Bipolar Disorder
(34:05) Psychedelic Drugs Enhance Neuroplasticity
(36:50) From Basic Research to Drug Development in the Pharma Industry
(40:10) Mental Health R&D at J&J
(43:40) S-Ketamine vs. K-Ketamine – Difference and Similarities
(46:35) Early-Stage Research in Big Pharma
(49:00) Big Pharma and Small Biotechs
(51:50) The decision to Start A New Company
(57:00) Foundation of Perception Neuroscience – From Early Stage Research to Clinical Phase 2 to Exit
(59:05) Atai Life Science – Continuing Development of the Compounds against Depression
Supporting links:
(01:00:00) Reasons for Becoming a Serial Entrepreneur After a Successful Exit Deal
(01:06:00) Drug Development is Simple – Given an Experienced Drug Development Team
(01:08:00) What is the unique approach of Gilgamesh Pharmaceutical?
(01:10:15) Target Product Profile of Psychedelic Drugs
(01:20:30) Gilgamesh Pharmaceuticals Mission and Vision
(01:23:20) Patents in Psychedelic Drug Development
(01:24:45) Business Model of Gilgamesh Pharmaceutical
(01:29:00) Artificial Intelligence in Psychedelic Drug Development
(01:33:14) Investing in the Psychedelic Drug Development Industry
(01:37:22) Life Science VCs in the Psychedelic Drug Development Industry
(01:39:00) Christian Angermayer, Peter Thiel, Mike Novogratz – Investors in Psychedelic Drug Development
(01:41:00) Investment Sentiment in the United States in Developing Novel Innovation
(01:43:00) Opinions on the Investment Market Situation in 2022+
(01:49:40) Gilgamesh Pharma Plans for the Coming Years
Support the show
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In this episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD)—a prevalent and debilitating condition. I also discuss the efficacy and mechanisms behind OCD treatments—both behavioral and pharmacologic as well as holistic and combination treatments and new emerging treatments, including directed brain stimulation. I explain the neural circuitry underlying repetitive “thought-action loops” and why in OCD, the compulsive actions merely make the obsessions even stronger. I review cognitive-behavioral therapies like exposure therapy and SSRIs, holistic approaches, and nutraceuticals, detailing the efficacy of each approach and what science says about how to combine and sequence treatments. I describe an often effective approach for treating OCD where clinicians use cognitive behavioral therapy (CBT) to deliberately bring patients into states of high anxiety while encouraging them to suppress compulsive actions in order to help them learn to overcome repetitious thought/action cycles. This episode should interest anyone with OCD, anyone who knows someone with OCD or OCPD, and more generally, those interested in how the brain works to control thoughts and actions, whether those thoughts are intrusive or not. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Obsessive-Compulsive Disorder (OCD) (00:03:01) Momentous Supplements, AG1 (Athletic Greens), Thesis, Eight Sleep (00:08:28) What is OCD and Obsessive-Compulsive Personality Disorder? (00:11:18) OCD: Major Incidence & Severity (00:15:10) Categories of OCD (00:21:33) Anxiety: Linking Obsessions & Compulsions (00:27:33) OCD & Familial Heredity (00:29:10) Biological Mechanisms of OCD, Cortico-Striatal-Thalamic Loops (00:39:36) Cortico-Striatal-Thalamic Loop & OCD (00:46:39) Clinical OCD Diagnosis, Y-BOCS Index (00:51:38) OCD & Fear, Cognitive Behavioral Therapy (CBT) & Exposure Therapy (01:01:56) Unique Characteristics of CBT/Exposure Therapy in OCD Treatment (01:10:18) CBT/Exposure Therapy & Selective Serotonin Reuptake Inhibitors (SSRIs) (01:22:30) Considerations with SSRIs & Prescription Drug Treatments (01:25:17) Serotonin & Cognitive Flexibility, Psilocybin Studies (01:31:50) Neuroleptics & Neuromodulators (01:36:09) OCD & Cannabis, THC & CBD (01:39:29) Ketamine Treatment (01:41:43) Transcranial Magnetic Stimulation (TMS) (01:46:22) Cannabis CBD & Focus (01:47:50) Thoughts Are Not Actions (01:51:27) Hormones, Cortisol, DHEA, Testosterone & GABA (02:00:55) Holistic Treatments: Mindfulness Meditation & OCD (02:03:28) Nutraceuticals & Supplements: Myo-Inositol, Glycine (02:09:45) OCD vs. Obsessive-Compulsive Personality Disorder (02:20:53) Superstitions, Compulsions & Obsessions (02:31:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
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Stephan Guyenet is a neuroscientist focused on the neuroscience of obesity and energy homeostasis. He is the author of the book, The Hungry Brain and founder/director of Red Pen Reviews. In this episode, Stephan explains how obesity has changed phenotypically over the course of human history as well as what might explain the dramatic increase in prevalence of obesity in the last few decades. He talks in depth about the role of genetics, the brain, and hormones like leptin play in the regulation of fat mass. He dives deep into two common theories of obesity—the carbohydrate-insulin model and the energy balance model and provides his take on which theory has stronger evidence. Additionally, he provides insights on how we’re hard-wired to think about food and the consequences of modern foods designed for maximal pleasure. Finally, he goes through the factors that affect body weight, set points, and provides takeaways for people wanting to take advantage of what we know about the brain’s role in regulating our body weight.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
A lot of young men today struggle in finding their footing in adulthood. They feel lost, directionless, and unsure of who they are and how to confidently and competently navigate the world.
Part of the reason for this is that most young men today lack something which was once a part of nearly every culture in the world, but has now almost entirely disappeared: a rite of passage.
My guest today didn't want his son to flounder on the way to maturity, nor to miss out on having an initiation into manhood, so he set out to create a 6-year journey for him that would help him move from boy to man. His name is Jon Tyson, and he's the author of The Intentional Father: A Practical Guide to Raise Sons of Courage and Character. Today on the show, Jon unpacks the components of the years-long journey into manhood he created for his son, beginning with how he brainstormed those components by doing "The Day Your Son Leaves Home" exercise. We then discuss how old Jon's son was when he started his rite of passage and why it began with him having a "severing dinner" with his mom. We get into what his rite of passage consisted of, from the kickoff ceremony to the challenges, experiences, trips, and daily rituals Jon used to impart values and teach his son the "5 Shifts of Manhood." Jon shares how moving his son's focus from being a good man, to being good at being a man, helped him get remotivated to continue the process, why his rite of passage included a gap year after high school, and how Jon celebrated the end of his son's journey into becoming a man. We also discuss whether Jon did something similar with his daughter. We end our conversation with some key principles any dad can use to start intentionally helping their kids become well-rounded individuals who can confidently step out on their own and into the world.
Resources Related to the Podcast AoM Article: The Importance of Fathers * AoM Article: The Importance of Male Rites of Passage * AoM Article: Male Rites of Passage From Around the World * AoM Article & Podcast: Man’s Need for Ritual * AoM Series on the origins, elements, and future of manhood * AoM Article: The 7 Habits — Begin With the End in Mind * AoM Article: The 3 Families Every Young Man Needs to Grow Up Well * James Hollis * AoM Article: Carry the Fire * Art of Manliness' Carry the Fire Zippo Lighter * AoM Article: What Is Manliness? * AoM Podcast #527 With Richard Rohr * The Power of Moments: Why Certain Experiences Have Extraordinary Impact by Chip and Dan Heath * The Way of Men* by Jack Donovan * AoM Podcast #49 With Jack Donovan * AoM Series on the Four Archetypes of the Mature Masculine * AoM Article: 100 Skills Every Man Should Know * AoM Article: 80+ Quotes on Men & Manhood
Connect With Jon Tyson* Primal Path * Jon on Twitter * Jon on IG
Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Travel can offer a lot of good: memory-making adventure, mind-expanding experiences, and plenty of fun and relaxation. It's not surprising then that most people say they'd like to travel more than they do. What's keeping them from fulfilling that desire? Well, one obstacle, especially these days, is that the high price of plane tickets puts flying out of reach.
My guest today can help you surmount this obstacle so you can get away more often. His name is Scott Keyes, and he's the founder of Scott's Cheap Flights and the author of Take More Vacations: How to Search Better, Book Cheaper, and Travel the World. Today on the show, Scott shares how scoring cheap flights can help you travel more often, the advantages of taking more frequent vacations, and the psychological benefit of planning your trips well in advance. We then get into the misconceptions people have about ticket pricing. From there we turn to Scott's strategies for booking cheap flights, beginning with why he recommends adopting a "Flight First" rather than "Destination First" approach. Scott shares the "Goldilocks" time window when cheap flights are most likely to pop up, the benefits of building flexibility into your itinerary, the days that are typically cheapest to fly, and his favorite search site to look for flights. He also explains how to use the 24-hour rule and Southwest Airlines as arbitrage in getting better prices on your tickets, and how to employ what he calls the "Greek Islands Strategy" to save money when flying internationally. We end our conversation with how to take advantage of "mistake fares," and whether the high prices you're seeing this summer are here to stay.
Connect With Scott Keyes* Scott's Cheap Flights * Scott on Twitter
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In this “Ask Me Anything” (AMA) episode, Peter discusses the nutritional profiles of various fruits and vegetables as a means of assessing their relative value. He explains the difference between eating them vs. drinking them, how processing fruits and vegetables can change their properties, and how one’s current state of health affects nutrition strategy when it comes to fruits and vegetable consumption. Additionally, Peter explains the potential benefits and negative effects of certain phytochemicals found in produce and concludes with a discussion of supplementing with green powders, multivitamins, and more.
If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #36 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
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My guest is Ido Portal, the world’s foremost expert on human movement. Ido has spent a lifetime studying, combining and evolving elements from an enormous range of martial arts, dance genres, athletic endeavors, and science, to develop a unified theory and practice of movement called “The Ido Portal Method.” Here we discuss all things movement, including the role of the nervous system, reflexive versus deliberate movement patterns, and the link between emotions and awareness in movement. We also discuss learning and neuroplasticity, the mind-body connection and how movement itself can be leveraged toward expanding other types of skills- cognitive, creative and otherwise. As one of the most sought out teachers of movement alive today, the knowledge Ido shares in this conversation can benefit everyone—children, adults, athletes, dancers, clinicians and trainers and the everyday person. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com - code "huberman" Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Ido Portal, Movement & Movement Practice (00:03:30) AG1 (Athletic Greens), ROKA, Helix Sleep (00:07:49) What is Movement? (00:10:56) Movement & the Body-Mind Connection (00:14:47) Entry Points to Movement (00:18:08) Early Education in Movement: Awareness, Play & Examination (00:21:19) Stillness, Movement & the Environment, Playfulness (00:31:34) Unique Postures, Types of Movement, Contents vs. Containers (00:40:50) Discomfort: Marker of Movement, Failures & Learning (00:47:05) Movement Diversity, Squat Challenge, Injury, Movement Evolution (00:56:36) Animal & Human Movements, Gain & Change (01:02:04) Core Movement, Emotion & Memory, Spinal Waves, Evolution (01:12:39) Song, Dance & Complex Language, Movement as Language, Consilience (01:21:39) Movement Culture, Community, Collective Knowledge, Wild & Wise (01:26:36) Potential for Movement, “Humming” (01:32:18) Instructiveness vs Permissiveness, Degrees of Freedom (01:35:50) Variety, Diversity & Virtuosity (01:38:06) Vision & Movement, Focus & Awareness, Panoramic Awareness (01:48:28) Hearing & Movement (01:52:43) Walking Gaits (01:56:55) Playful Variability & Evolution, Improvisation & Openness (02:03:05) Reactivity & Personal Space, Touch & Proximity to Others, Play & Discomfort (02:18:13) Visualization & Experience, Feedback (02:20:14) Linear Movement & Movement Investigation, Examination (02:31:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
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In this episode, I explain the science behind limb range of motion and flexibility and how to increase them by using science-supported protocols. Flexibility is crucial for physical movements and can help prevent injuries, decrease inflammation, modulate physical and mental pain, impact exercise recovery speed and even potentially slow the progression of certain diseases. I explain the biology of flexibility, including the specific neural mechanisms that sense stretch and load (i.e., tension) on the muscles and limbs, as well as how specific brain regions like the insula combine those signals to ultimately control limb range of movement. I also provide science-based stretching and “micro-stretching” protocols that reliably improve limb flexibility with the minimum necessary time investment. I review all the details of those stretching protocols: how often to do them, for how long, their timing relative to other exercises, sets, the time between sets, measuring progress and more. All people, physically active or not, should benefit from the information and tools described in this episode. Thank you to our sponsors Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Flexibility & Stretching (00:02:57) Thesis, InsideTracker, Eight Sleep (00:07:22) Innate Flexibility (00:09:23) Movement: Nervous System, Connective Tissue & Muscle; Range of Motion (00:17:51) Golgi Tendon Organs (GTOs) & Load Sensing Mechanisms (00:20:20) Decreased Flexibility & Aging (00:22:38) Insula, Body Discomfort & Choice (00:30:02) von Economo Neurons, Parasympathetic Activation & Relaxation (00:42:00) Muscle Anatomy & Cellular ‘Lengthening,’ Range of Motion (00:47:16) Tool: Protocol - Antagonistic Muscles, Pushing vs. Pulling Exercises (00:51:57) Types of Stretching: Dynamic, Ballistic, Static & PNF (Proprioceptive Neuromuscular Facilitation) (00:59:36) Tool: Increasing Range of Motion, Static Stretching Protocol, Duration (01:05:56) Tool: Static Stretching Protocol & Frequency (01:13:55) Tool: Effective Stretching Protocol (01:17:12) Tool: Warming Up & Stretching (01:19:17) Limb Range of Motion & General Health Benefits (01:25:30) PNF Stretching, Golgi Tendon Organs & Autogenic Inhibition (01:31:23) Tool: Anderson Protocol & End Range of Motion, Feeling the Stretch (01:32:50) Tool: Effectiveness, Low Intensity Stretching, “Micro-Stretching” (01:41:33) Tool: Should you Stretch Before or After Other Exercises? (01:45:41) Stretching, Relaxation, Inflammation & Disease (01:51:37) Insula & Discomfort, Pain Tolerance & Yoga (02:00:36) Tools: Summary of Stretching Protocols (02:03:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
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Ray Dalio is the founder and co-chief investment officer of Bridgewater, the largest hedge fund in the world. He’s one of the 100 richest people on Earth. He’s also a best-selling author.
In today’s episode, Zachary Crockett chats with Dalio about his latest book, “The Changing World Order,” which uses a historical lens to examine why empires rise and fall — and why the US may be showing some signs of decline.
We cover a range of topics about the economy and Dalio’s life, including:
The 3 biggest issues America is facing right now
What’s driving the debt crisis
The growing wealth gap (and what we should do about it)
Thoughts on inflation and an impending recession
What to invest in during times of volatility
Whether or not crypto can become a reserve currency
Dalio’s worst failures as an investor
Common traits of successful people
The role luck plays in reaching the top
How Dalio helped McDonald’s launch chicken nuggets
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Trung T. Phan is a creator in the tech, business, and media space. His Twitter threads are full of knowledge and humor, and he also co-hosts the “Not Investment Advice” podcast. Follow Trung on Twitter at https://twitter.com/TrungTPhan and subscribe to his newsletter at https://trungtphan.com/subscribe/
Show Notes:
Books Mentioned:
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IN THIS EPISODE OF THE HUMAN UPGRADE™...
… you’ll learn why every breath you take makes a difference in how your entire body functions. The way you breathe affects the quality of your life and every one of your body systems. Full stop. This goes for adults and kids alike.
In this special edition, breathing experts Patrick McKeown (“THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life”) and James Nestor (“Breath: The New Science of a Lost Art”) approach the topic from diverse perspectives, but agree on a lot. Especially the benefits of nose breathing and the detriment of mouth breathing.
They explain the biochemical, biomechanics and psychological components of how you breathe. They also present exciting new research in pulmonology, psychology, biochemistry and human physiology that shows how making even slight adjustments to the way you inhale dramatically influences things like:
That's just the start of what you can change when you change your breathing. Big claims, yes. All true. And even bigger benefits for you.
Breathing can nurture your body, center you, and rebalance you. When you start harnessing the power of your breath, you're going to feel incredibly better than you do right now.
Patrick McKeown, an author, educator and one of the world’s leading breathing re-education experts, has researched breathing for more than two decades. Listen to more: Shut Your Mouth! Nose Breathing Improves All Your Body Systems – Patrick McKeown – #835
James Nestor, a San Francisco-based science journalist, author, surfer, free diver, adventurer, and speaker, set out on a decade-long quest to find out where our breathing went wrong—and how to fix it. Listen to more: Breathing Essentials That Will Change Your Life – James Nestor – #751
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Arnold Schwarzenegger, the movie star-turned-California governor, has been interested in business since long before he was Conan or the Terminator. For more than four decades, his behind-the-scenes partner has been Paul Wachter, whose Main Street Advisors was born 25 years ago, with Schwarzenegger's encouragement. The modern multihyphenate -- think LeBron, Drake, Billie Eilish -- are following a template the pair established in the 1980s, as Schwarzenegger successfully expanded his popularity and wealth through savvy dealmaking. The key element: Don't just endorse when you can own a piece of the product.
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest this episode is Dr. Paul Conti, M.D., a psychiatrist and expert in treating trauma, personality disorders and psychiatric illnesses and challenges of various kinds. Dr. Conti earned his MD at Stanford and did his residency at Harvard Medical School. He now runs the Pacific Premiere Group—a clinical practice helping people heal and grow from trauma and other life challenges. We discuss trauma: what it is and its far-reaching effects on the mind and body, as well as the best treatment approaches for trauma. We also explore how to choose a therapist and how to get the most out of therapy, as well as how to do self-directed therapy. We discuss the positive and negative effects of antidepressants, ADHD medications, alcohol, cannabis, and the therapeutic potential of psychedelics (e.g., psilocybin and LSD), ketamine and MDMA. This episode is must listen for anyone seeking or already doing therapy, processing trauma, and/or considering psychoactive medication. Both patients and practitioners ought to benefit from the information. Thank you to our sponsors ROKA: https://www.roka.com/huberman InsideTracker: https://insidetracker.com/huberman Blinkist: https://www.blinkist.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Paul Conti, Trauma & Recovery (00:02:30) ROKA, InsideTracker, Blinkist (00:07:00) Defining Trauma (00:14:05) Guilt & Shame, Origins of Negative Emotions (00:21:38) Repeating Trauma, the Repetition Compulsion (00:28:23) How to Deal with Trauma & Negative Emotions/Arousal (00:37:17) Processing Trauma, Do You Always Need a Therapist? (00:45:30) Internal Self-talk, Punishing Narratives & Negative Fantasies (00:51:10) Short-Term Coping Mechanisms vs. Long-Term Change (00:53:22) Tools: Processing Trauma on Your Own, Journaling (00:57:00) Sublimination of Traumatic Experiences (01:02:34) Tool: Finding a Good Therapist (01:07:20) Optimizing the Therapy Process, Frequency, Intensity (01:14:51) Tool: Self-Awareness of Therapy Needs, Mismatch of Needs (00:16:35) Self-talk & Journaling, Talking to Trusted Individuals (01:19:00) Prescription Drugs & Treating Trauma, Antidepressants, Treating Core Issues (01:28:35) Short-term vs. Long-Term Use of Prescription Drugs, Antidepressants (01:32:18) Attention Deficient Hyperactivity Disorder (ADHD) & Prescription Drugs (01:37:31) Negative Effects of ADHD Prescription Drugs (01:40:37) Alcohol, Cannabis – Positive & Negative Effects (01:44:53) Psychedelics: Psylocibin & LSD, Therapeutic Uses, Trauma Recovery (01:54:32) Sentience, Language, Animals (01:55:48) Psychedelic Hallucinations, Trauma Recovery (02:00:01) MDMA (Therapeutic Uses) (02:04:47) Clinical Aspects of MDMA (02:07:28) Language, Processing Trauma, Social Media, Societal Divisions (02:15:09) Defining “Taking Care of Oneself” (02:21:13) Dr. Conti, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Tyler Cowen is the Holbert L. Harris Chair of Economics at George Mason University, a columnist, podcaster and an author.
Finding and recruiting the best talent is perhaps the most important job that an organisation has. Skilful, enthusiastic, keen staff can make or break a business, so why is it that most companies are mostly useless when it comes to discovering talent?
Expect to learn whether population collapse is coming very soon, whether talent is innate or developed, why there is a crisis of talent when we have more people on earth than ever before, whether you should look at someone's parents before hiring them, the best questions to ask in an interview, what SpaceX's hiring strategy teaches us about thoroughness, how Tyler screens young staff for the most original thinkers and much more...
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The Kevin Bass Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this podcast, I discuss a paper that shows profound reductions in sperm concentration (nearly 75%), total sperm count (2/3), and sperm motility (half) after just two 15-minute sauna sessions per week for three months (PMID 23411620). These changes were not reversed after three months cessation of sauna use; a full six months were required for these changes to reverse. It is unknown how the sauna may impact spermatogenesis among those who already have impaired testicular function or during development.
It is important to fully explain the risks and harms of interventions that are massively hyped on social media. This podcast offers itself as a corrective to overhyping by the most popular and well-known American health influencers.
===
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For more, find me at:
PODCAST The Kevin Bass Show
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode, I discuss grief and the challenges of processing losses of different kinds. I explain the biological mechanisms of grief, including how neural circuits for emotional and factual memory combine with those for love and attachment, to create feelings of absence and yearning. I discuss how grief is distinct from depression, yet why they can feel so similar. I also provide science-based tools to assist with the grieving process, including how to reframe and remap the relationship with those we have lost while still maintaining a strong emotional connection to them. I also explain the importance of having and building strong foundational psychological and biological states so that we can better cope with grief when it happens. Finally, I describe tools to adjust those states, including those for accessing sleep, managing stress and emotional swings. This episode is for those suffering from grief but also for everyone, given that we all experience grief at some point in our lives. We recorded this episode before the recent mass shooting tragedies in the United States. While we hope the information in this episode will be of use to anyone suffering from grief of any kind and at any time, we are also careful to acknowledge that many people require additional support and resources. For that reason, we include mention of such resources and we generally hope people will access them if needed. Thank you to our sponsors Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://www.roka.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Grief & Bereavement (00:03:44) Eight Sleep, InsideTracker, ROKA (00:08:35) Grief vs. Depression, Complicated Grief (00:12:20) Stages of Grief, Individual Variation for Grieving (00:16:05) Grief: Lack & Motivation, Dopamine (00:23:15) Three Dimensions of Relationships (00:29:52) Tool: Remapping Relationships (00:37:15) Grief, Maintaining Emotional Closeness & Remapping (00:44:40) Memories of Loved Ones & Remapping Attachments (00:48:04) Yearning for Loved Ones: Memories vs. Reality, Episodic Memory (00:51:40) Tools: Adaptively Processing Grief, Counterfactual Thinking, Phantom Limbs (01:00:32) Tool: Remembering Emotional Connection & Processing Grief (01:04:03) Memories, Hippocampal Trace Cells & Feeling An Absence (01:10:14) Yearning & Oxytocin, Individualized Grief Cycles (01:18:24) Tool: Complicated Grief & Adrenaline (Epinephrine) (01:24:37) Sentimental Attachment to Objects (01:26:13) Why do Some People Grieve More Quickly? Individual Attachment Capacity (01:29:42) “Vagal Tone,” Heart Rate, Breathwork & Grief Recovery (01:42:32) Complicated Grief & Cortisol Patterns (01:48:50) Tool: Improving Sleep & Grieving (01:54:28) Tools: Grief Processing & Adaptive Recovery (02:03:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Links: * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (02:40) - Tip 1 Dr. House (05:25) - Tip 2 The Holiday (08:30) - Tip 3 Misery Love Company (09:00) - Tip 4 Hired Too Many (12:45) - Tip 5 Super Power (17:40) - Tip 6 Tesla Master Plan (20:15) - Tip 7 Calendar Audit (21:10) - Tip 8 Peer Groups (22:00) - Tip 9 Kickoff Document
Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
• #218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Ben Hunt is the creator and primary author of Epsilon Theory, and co-founder and CIO at Second Foundation Partners.
Epsilon Theory is a newsletter that examines markets through the lenses of game theory and history. Over 100,000 professional investors and allocators across 180 countries read Epsilon Theory for its fresh perspective and novel insights into market dynamics.
You can follow Ben on Twitter at https://twitter.com/EpsilonTheory and read Epsilon Theory here: https://www.epsilontheory.com/
Show Notes:
Books Mentioned:
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Dr. Wendy Suzuki, Ph.D., Professor of Neural Science and Psychology and (soon) Dean of New York University, whose research focuses on memory, attention, brain plasticity and simple, daily habits that can be leveraged to improve learning, focus, memory and cognitive ability. We discuss the role of cardiovascular exercise, weight training, deliberate cold exposure, meditation, verbal affirmations, sleep, and other behavioral practices for enhancing learning, mood and stress management, and increasing attention span. Dr. Suzuki shares the mechanisms by which these practices change our brain in order to improve cognitive function fast and reduce age-related cognitive decline. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Blinkist: https://www.blinkist.com/huberman Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Wendy Suzuki, Learning & Memory (00:02:50) AG1 (Athletic Greens), InsideTracker, Blinkist (00:07:27) How Memories Form (00:10:14) Hippocampus: Memory, Association & Imagination (00:16:20) Encoding Long-Term Memory (00:18:48) One-Trial Memory (00:21:56) Tool: Foundational Habits to Enhance Brain Performance (00:30:39) Exercise & Improved Memory, Making a “Big, Fat, Fluffy Hippocampus” (00:39:35) Cardiovascular Exercise, BDNF (Brain-Derived Neurotrophic Factor) (00:48:48) Neurogenesis (New Neuron Production) in Adults (00:51:50) Effects of Exercise on Memory (00:56:31) Tool: Timing Daily Exercise, Cortisol (01:00:02) Age-Related Memory Loss, Daily Exercise (01:05:33) Tool: Exercise Protocol for Improving Cognition (01:12:17) Anticipating Exercise, Daily Habits & Behaviors (01:17:09) “Every Drop of Sweat Counts” – Exercise & Cognitive Function (01:20:58) Positive Affirmations & Mood (01:27:28) Meditation & Cognitive Performance (01:32:27) How Meditation Works, Focusing on the Present (01:37:14) Tool: Strategies to Increase Attention (01:42:50) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Quah (Q & A), Sal, Adam & Justin coach three Pump Heads via Zoom.
Related Links/Products Mentioned
Featured Guest/People Mentioned
My First Million: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Links: * Native * Haldirams * Manscaped * Brumate * Moiz's sell sheet tweet * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter.
Show Notes: (04:20) - Starting Native in secret (13:50) - Figuring out your competitive advantage (24:00) - Common mistakes in DTC brands (35:00) - Stock tips on D2C tech companies (38:10) - Real estate investments
Econtalk: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
What's the single best thing happening in technology right now? According to entrepreneur and venture capitalist Marc Andreessen, it's the ability to live in rural Wisconsin but still earn a Silicon Valley salary. Andreessen also explains to EconTalk host Russ Roberts why software is still eating the world, why he's an optimist, and why he's still bullish on Bitcoin and the blockchain.
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Nick Maggiulli is a financial educator, author of the blog “Of Dollars and Data”, and the newly released book “Just Keep Buying: Proven Ways To Save Money And Build Your Wealth.”
In this episode, we talk with Nick about the robust empirical research that has gone behind the insights and ideas presented in his new book!
You can follow Nick on Twitter at https://twitter.com/dollarsanddata and buy his book at https://ofdollarsanddata.com/justkeepbuying/
Show Notes:
Books Mentioned:
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode I explain the mechanisms by which different types of memories are established in our brain and how to leverage the amount and timing of key neurochemicals and hormones, such as adrenaline (aka epinephrine) and cortisol, to improve your learning and memory abilities. I describe multiple science-based protocols to do this, including repetition, caffeine, emotional states, deliberate cold exposure, sleep, meditation, and the role of vision, including taking “mental snapshots.” I also describe how exercise and an associated hormone, osteocalcin, can improve cognitive ability and memory formation. I also describe unique aspects and forms of memory such as photographic memory, extreme facial recognition (aka super recognition), and the phenomenon known as déjà vu. Thank you to our sponsors Eight Sleep: https://www.eightsleep.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Memory, Improving Memory (00:02:45) Eight Sleep, Thesis, InsideTracker (00:07:54) Sensory Stimuli, Nervous System & Encoding Memory (00:11:12) Context & Memory Formation (00:13:46) Tool: Repetition, Improving Learning & Memory (00:17:11) Co-Activation and intensity Neuron Activation (00:20:50) Different Types of Memory (00:25:40) Memory Formation in the Brain, Hippocampus (00:28:00) Hippocampus, Role in Memory & Learning, Explicit vs. Implicit Memory (00:31:49) Emotion & Memory Enhancement (00:36:44) Tool: Emotion Saliency & Improved Memory (00:41:42) Conditioned-Placed Avoidance/Preference, Adrenaline (00:47:14) Adrenaline & Cortisol (00:49:35) Accelerating the Repetition Curve & Adrenaline (00:53:03) Tool: Enhancing Learning & Memory - Caffeine, Alpha-GPC & Stimulant Timing (01:00:50) Tool: Enhancing Learning & Memory - Sleep, Non-Sleep Deep Rest (NSDR) (01:04:48) Tool: Enhancing Learning & Memory - Deliberate Cold Exposure, Adrenaline (01:08:42) Timing of Adrenaline Release & Memory Formation (01:12:36) Chronically High Adrenaline & Cortisol, Impact on Learning & Memory (01:15:12) Adrenaline Linked with Learning: Not a New Principle (01:17:25) Amygdala, Adrenaline & Memory Formation, Generalization of Memories (01:22:20) Tool: Cardiovascular Exercise & Neurogenesis (01:27:00) Cardiovascular Exercise, Osteocalcin & Improved Hippocampal Function (01:29:59) Load-Bearing Exercise, Osteocalcin & Cognitive Ability (01:34:41) Tool: Timing of Exercise, Learning & Memory Enhancement (01:37:29) Photographic Memory (01:38:49) “Super Recognizers,” Facial Recognition (01:41:46) Tool: Mental Snapshots, Photographs & Memory Enhancement (01:49:12) Déjà Vu (01:53:24) Tool: Meditation, Daily Timing of Meditation (02:02:21) How to Enhance Memory (02:05:51) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Jack Murphy Live: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Jack Murphy sits down with Luke Burgis, author of "Wanting: The Power of Mimetic Desire in Everyday Life" - an insightful book that draws on the work of French polymath René Girard to bring this hidden force to light and reveals how it shapes our lives and societies.
Why do you want what you want?
And how do we influence what other's want?
Once you understand the power of memetic contagion, you'll see it everywhere.
"A groundbreaking exploration of why we want what we want, and a toolkit for freeing ourselves from chasing unfulfilling desires. Gravity affects every aspect of our physical being, but there’s a psychological force just as powerful―yet almost nobody has heard of it. It’s responsible for bringing groups of people together and pulling them apart, making certain goals attractive to some and not to others, and fueling cycles of anxiety and conflict. In Wanting, Luke Burgis draws on the work of French polymath René Girard to bring this hidden force to light and reveals how it shapes our lives and societies. According to Girard, humans don’t desire anything independently. Human desire is mimetic―we imitate what other people want. This affects the way we choose partners, friends, careers, clothes, and vacation destinations. Mimetic desire is responsible for the formation of our very identities. It explains the enduring relevancy of Shakespeare’s plays, why Peter Thiel decided to be the first investor in Facebook, and why our world is growing more divided as it becomes more connected. Wanting also shows that conflict does not arise because of our differences―it comes from our sameness. Because we learn to want what other people want, we often end up competing for the same things. Ignoring our large similarities, we cling to our perceived differences."
https://www.amazon.com/Wanting-Power-Mimetic-Desire-Everyday/dp/1250262488
Jack Murphy's Book, "Democrat To Deplorable," Now Available On Audiobook: https://adbl.co/3qXvlEY
Liminal Order: https://www.liminal-order.com
Follow Jack Murphy: Twitter: https://twitter.com/jackmurphylive
Facebook: https://www.facebook.com/jackmurphylive
Instagram: https://www.instagram.com/jackmurphylive/
Rumble: https://rumble.com/c/JackMurphyLive
Minds: https://www.minds.com/jackmurphylive/
MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Quah (Q & A), Sal, Adam & Justin answer Pump Head questions about growing stubborn biceps, whether changing phases is effective because of “muscle confusion,” if it is ok to train to failure if only focusing on a muscle group once a week, and whether bodybuilding is healthy.
Related Links/Products Mentioned
People Mentioned
Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
View the Show Notes Page for This Episode
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In this special episode of The Drive, we have pulled together a variety of clips from previous podcasts about exercise to help listeners understand this topic more deeply, as well as to identify previous episodes which may be of interest. In this episode, Peter discusses his framework for exercise, what he’s really optimizing for, and how to train today to be prepared for a good life at age 100. He describes the importance of strength and stability, and why deadlifting is an important tool to consider for longevity. Additionally, he details why training in zone 2 and zone 5 is important, gives a primer on VO2 max, and describes the most effective ways to engage in those types of exercise. Finally, Peter reveals his current exercise routine.
We discuss:
Connect With Peter on Twitter, Instagram, Facebook and YouTube
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode I describe the neural mechanisms that activate and control aggressive states and beahviors and the role of hormones—estrogen and testosterone—in mediating violent and and/or competive aggression. I also describe tools that can be used to modulate the factors that have been shown to ‘prime’ an individual for aggression, including sunlight, estrogen sensitivity, competition within social settings, and overall stress levels, and the hormone cortisol. I discuss how substances such as caffeine and alcohol can impact impulsive behaviors, and how nutrition and supplementation can be used to regulate mood and aggression. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com -- code: huberman Helix Sleep: https://www.helixsleep.com/huberman See Andrew Huberman Live: The Brain Body Contract https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Aggression, Types of Aggression (00:03:33) AG1 (Athletic Greens), ROKA, Helix Sleep (00:08:29) Neural Circuits for Aggression, “Hydraulic Pressure Model” (00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH) (00:22:14) Psychiatric Disorders & Aggression (00:23:36) Stimulation of the VMH, Estrogen Receptors & Aggression (00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting (0:35:56) Testosterone & Competitiveness/Estrogen & Aggression (00:43:00) Sunlight, Melatonin & Aggression (00:45:46) Cortisol, Serotonin & Aggressive Behaviors (00:51:56) Tool: Omega-3 Supplementation & Mood (00:54:18) Tool: Sunlight, Sauna & Cortisol Reduction (00:55:54) Tool: Ashwagandha & Cortisol Reduction (00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity (01:00:37) Testosterone & Aggression, Competitive Work Environments (01:05:07) Testosterone, Amygdala, Challenge & Effort (01:09:27) Caffeine, Alcohol & Impulsivity (01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression (01:17:18) Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior (01:24:10) Factors Affecting the “Hydraulic Pressure Model” of Aggression (01:25:44) Book by Dr. David Anderson, Aggression & Social Relationships (01:27:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Chris Sacca is the Founder and Chairman @ Lowercase Capital, one of the best performing funds in the history of venture capital with a portfolio including Uber, Stripe, Twitter, Instagram, Twilio, Docker and many more. * Why does Chris believe we have bred a generation of asshole kids?
Anne Wojcicki is the Founder & CEO @ 23andMe, offering DNA testing with the most comprehensive ancestry breakdown, personalized health insights, and more.
Harley Finkelstein is the President of Shopify. Over the last 12 years, Harley has partnered with Tobi to the tune of building Shopify’s revenue to over $4.6BN in 2021 and the team to over 10,000 employees.
Deena Shakir is a Partner at Lux Capital, one of the leading firms investing in emerging science and technology ventures at the outermost edges of what is possible.
Eric Liaw is a General Partner @ IVP, one of the leading later-stage venture capital and growth equity firms of the last decade with $8.7 billion of committed capital and a 40-year IRR of 43.1%.
Scott Dietzen is Vice Chairman of the Board of Pure Storage and served as the Company’s CEO from 2010 to 2017. Under his leadership, Pure grew to thousands of employees and
completed an IPO in 2015.
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Grimes is a musician, artist, singer, songwriter, producer, and director. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Novo: https://novo.co/lex – Lambda: https://lambdalabs.com/lex – Public Goods: https://publicgoods.com/lex and use code LEX to get $15 off – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Grimes’s Twitter: https://twitter.com/Grimezsz Grimes’s Instagram: https://www.instagram.com/grimes PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon:
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Ben Patrick (Knees Over Toes Guy) is an athletic coach and an author.
Keeping our bodies bulletproof is something everyone wants as they age. Bad knees, backs and shoulders not only stop you from doing the things you want in sport, but then begin to suck the enjoyment out of your life too. Ben has some solutions.
Expect to learn the 3 most important exercises to maximise your body's robustness, what Ben's biggest takeaways have been from Andrew Huberman, the relationship between flexibility and strength, how to make your shoulders more mobile and less painful, the optimal training frequency to see results and much more...
Sponsors:
Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/
Get a Free Sample Pack of all LMNT Flavours at https://www.drinklmnt.com/modernwisdom (discount automatically applied)
Get 20% discount on the highest quality CBD Products from Pure Sport at https://bit.ly/cbdwisdom (use code: MW20)
Get 15% discount on Craftd London’s jewellery at https://bit.ly/cdwisdom (use code MW15)
Extra Stuff:
Check out Ben's website - https://www.atgonlinecoaching.com
Buy Ben's book - https://amzn.to/37M5USu
Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/
To support me on Patreon (thank you): https://www.patreon.com/modernwisdom
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Get in touch.
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Twitter: https://www.twitter.com/chriswillx
YouTube: https://www.youtube.com/modernwisdompodcast
Email: https://chriswillx.com/contact/
Jocko Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Andrew Huberman, Ph.D., is a neuroscientist and tenured Professor in the Department of Neurobiology at the Stanford University School of Medicine. He has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning.
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Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
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Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder, and previous guest on The Drive. In the first half of this episode, Layne dives deep into the topic of energy balance, including the role that macronutrients and calories play in weight loss. He describes how many people struggle with tracking food and calories on their own across a variety of diets and how all of this can impact nutritional habits and behaviors. In the second half of the episode, Layne discusses the importance of protein and weightlifting for improving one’s body composition and increasing muscle mass. He explains how he would prescribe different training and nutrition programs for two hypothetical clients—a 50-year-old female who is entering menopause and wants to improve her health, and a 40-to-50-year-old male who wants to maximize muscle mass. Additionally, Layne discusses a number of supplements that could potentially benefit a training program including whey protein, branch chain amino acids, creatine, nitric oxide boosters, and more.
We discuss:
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Rhonda Patrick, Ph.D. She earned her doctoral degree in biomedical science from St. Jude Children’s Research Hospital at the University of Tennessee Health Science Center and has become one of the leading public health educators on the brain and general health, aging, cancer, and nutrition. We discuss the four major categories of micronutrients that regulate cellular and organ stress and antioxidants, inflammation, hormone regulation, immune system, and longevity. Dr. Patrick provides actionable protocols for obtaining key micronutrients from food and/or supplement-based sources. Additionally, Dr. Patrick outlines protocols for deliberate cold and deliberate heat exposure to benefit metabolism, cardiorespiratory fitness, mental health, and lifespan. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Rhonda Patrick – Micronutrients, Cold & Heat Exposure (00:03:12) Momentous Supplements (00:04:27) The Brain-Body Contract (00:05:30) AG1 (Athletic Greens), Thesis, InsideTracker (00:09:42) Stress Response Pathways, Hormesis (00:16:38) Plants, Polyphenols, Sulforaphane (00:21:12) Tools 1: Sulforaphane - Broccoli Sprouts, Broccoli, Mustard Seed (00:23:50) Tool 2: Moringa & Nrf2 Antioxidant Response (00:25:25) Sulforaphane: Antioxidants (Glutathione) & Air Pollution (Benzene Elimination) (00:27:10) Plants & Stress Response Pathways, Intermittent Challenges (00:29:35) Traumatic Brain Injury, Sulforaphane, Nrf2 (00:35:08) Tools 3: Omega-3 Fatty Acids (ALA, EPA & DHA), Fish Oil, Oxidation (00:48:40) EPA Omega-3s & Depression (00:52:02) Krill Oil vs. Fish Oil Supplements? (00:54:23) Benefits of Omega-3 Fatty Acids, Omega-3 Index & Life Expectancy (00:59:24) Tool 4: Food Sources of EPA Omega-3s (01:06:07) Omega-3 Supplementation, Omega-3 Index Testing (01:10:22) Benefits of Omega-3s (01:14:40) Tool 5: Food Sources of DHA Omega-3s (01:17:07) Vitamin D & Sun Skin Exposure (01:22:18) Role of Vitamin D, Gene Regulation (01:25:30) Tool 6: Vitamin D Testing & Vitamin D3 Supplementation (01:33:15) Tool 7: Skin Surface Area & Sun Exposure, Vitamin D (01:34:23) Vitamin D & Longevity (01:36:46) Sun Exposure & Sunscreen (01:40:30) Role of Magnesium, Magnesium Sources, Dark Leafy Green Vegetables (01:44:50) Tool 8: Magnesium Supplements: Citrate, Threonate, Malate, Bisglycinate (01:50:57) Tool 9: Deliberate Cold Exposure Protocol & Mood/Anxiety (01:59:22) Tool 10: Cold Exposure, Mitochondria UCP1 & Heat Generation (02:02:30) Tool 11: Cold & Fat ‘Browning’, PGC-1alpha, Metabolism (02:05:08) Cold Exposure & High-Intensity Interval Training (HIIT), PGC-1alpha, Muscle (02:08:04) Tools 12: Exercise, HIIT, Tabata & Sauna (02:13:30) Tool 13: Sauna, Endorphins/Dynorphins, Mood (02:17:45) Tool 14: Mild Stress, Adrenaline & Memory (02:19:53) Sauna, Vasodilation & Alzheimer’s and Dementia Risk (02:25:30) Sauna Benefits, Cardiorespiratory Fitness, Heat Shock Proteins (HSPs) (02:31:29) Insulin signaling, FOXO3 & Longevity (02:33:22) Tools 16: Sauna Protocols, Hot Baths & Fertility (02:37:41) Tool 17: Exercise & Longevity, Osteocalcin (02:41:37) Tools 18: Red Light Sauna? Infrared Sauna? Sauna & Sweating of Heavy Metals (02:47:20) FoundMyFitness Podcast, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Huberman Lab on Instagram & Twitter Title Card Photo Credit: Mike Blabac Disclaimer
Philosophize This!: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Today we continue our discussion of Emerson.
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Michael Saylor is the CEO of MicroStrategy and a prominent holder and proponent of Bitcoin. Please support this podcast by checking out our sponsors: – Scale: https://scale.com/lex – Coinbase: https://coinbase.com/lex to get $10 in free Bitcoin – Audible: https://audible.com/lex to get $9.95 a month for 6 months – NetSuite: http://netsuite.com/lex to get free product tour – SimpliSafe: https://simplisafe.com/lex and use code LEX EPISODE LINKS: Michael’s Twitter: https://twitter.com/saylor MicroStrategy: https://microstrategy.com/ Michael’s Book: https://amzn.to/37J2iA0 Book mentioned: https://amzn.to/3jwsIaP PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out
a16z Live: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Katherine Boyle, General Partner at a16z is joined by Hadrian founder and CEO Chris Power, Packy McCormick, founder of Not Boring, and a16z co-founder Marc Andreessen to discuss the opportunity to automate and upskill in the precision parts industry and shore up U.S. manufacturing with new technology.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
I describe the mechanisms by which deliberate heat exposure impacts body temperature, metabolism, heart health, hormone production, exercise recovery, cognition, mood, and longevity. I detail specific protocols for deliberate heat exposure, including exposure times, temperature ranges to consider, time of day, and delivery mechanisms (sauna vs. hot bath vs. open air heat, etc.) in order to achieve different specific outcomes, including dramatic growth hormone releases, or reduction in cortisol levels. I also discuss the ability of locally applied heat to heal or otherwise improve various bodily tissues and new data on how local application of heat may induce the conversion of metabolically sluggish white fat to metabolically robust beige fat. Thank you to our sponsors LMNT: https://drinklmnt.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA - https://www.roka.com - code "huberman" See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Momentous I am pleased to announce that the Huberman Lab Podcast is now partnered with Momentous. Momentous supplements are of the very highest quality; each is third-party tested for purity and accuracy of dosage. To learn more about the Huberman Lab Podcast-Momentous partnership, the supplements I that take, and stay up-to-date with future product announcements, visit: https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Heat & Health (00:03:37) Momentous Supplements (00:04:52) The Brain-Body Contract (00:05:46) LMNT, InsideTracker, ROKA (00:09:31) Body Shell Temperature vs. Body Core Temperature (00:13:28) Thermal Regulation, Hyperthermia (00:17:36) Heat Removal Circuits, Pre-Optic Hypothalamus (POA) (00:26:30) Protocols & Benefits of Deliberate Heat Exposure (00:33:37) Tools & Conditions for Deliberate Heat Exposure (00:38:47) Deliberate Heat Exposure, Cortisol & Cardiovascular Health (00:44:50) Heat Shock Proteins (HSPs), Molecular Mechanisms of Heat Regulation (00:47:56) Longevity & Heat Exposure, FOXO3 (00:52:30) Deliberate Cold & Heat Exposure & Metabolism (00:54:48) Deliberate Heat Exposure & Growth Hormone (01:04:32) Parameters for Heat & Cold Exposure (01:08:26) Circadian Rhythm & Body Temperature, Cold & Heat Exposure (01:12:00) Heat Exposure & Growth Hormone (01:16:20) Tool: Hydration & Sauna (01:17:10) Heat, Endorphins & Dynorphins, Mood (01:28:44) Tool: Glabrous Skin To Heat or Cool (01:35:33) Local Hyperthermia, Converting White Fat to Beige Fat, Metabolism (01:47:00) Hormesis/Mitohormesis & Heat/Cold Exposure (01:49:11) Benefits of Heat Exposure (01:51:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
As Chamath Palihapitiya put it back in April 2021, 10-K Diver is “one of the best fintwit accounts on Twitter.” 10-K Diver loves breaking down complex financial topics and helping people understand them via engaging Twitter threads.
You can follow 10-K Diver on Twitter at https://twitter.com/10kdiver and read all his threads at https://10kdiver.com/twitter-threads/
Show Notes:
Books Mentioned:
Nudge - Marketing Science Simplified✓Claim: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
When you think of influence you probably think of Beyonce, Ronaldo, or Obama. But you don’t think about yourself. In today’s show, Professor Vanessa Bohns talks about the influence you already have. She explains why we underestimate how many people like our company, why we overestimate how social our friends are, and how we change our views depending on who we’re talking to. Tune in and I guarantee you’ll learn something surprising about yourself. Vanessa’s book: https://www.vanessabohns.com/ Follow Vanessa on Twitter: https://twitter.com/profbohns Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
What are the best strategies to get people to say “Yes” to your requests in life? Acclaimed psychologist Robert Cialdini dives deep into the seven small things that make a huge impact in influencing others, as well as the difference between being influenced and being manipulated into making decisions. What are the tactics, how do they work, and how do we defend against them? This episode is jam-packed with practical advice that will make you more persuasive in life.
Known colloquially as “The Godfather of Influence,” Cialdini is a foundational expert in the science of influence and how to apply it ethically in business. His books, including Influence: Psychology of Persuasion and Pre-Suasion, have sold more than 7 million copies in 44 different languages, and he is the Regents’ Professor Emeritus of Psychology and Marketing at Arizona State University.
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
I describe the mechanisms by which different wavelengths of light impact the cells, tissues and organs of the human body, and how specifically timed light exposure of specific wavelengths can be used to improve sleep, enhance alertness, modulate hormone levels, and improve mood. I also explain the use of ultraviolet and infrared phototherapies to relieve pain increase testosterone and estrogen levels; improve skin health, appearance and wound healing; and how red light can be used to offset age-related vision loss and provide neuroprotection. Throughout the episode, I describe the mechanisms of light-based therapies and actionable tools that people can use positively impact mental and physical health. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman LMNT: https://drinklmnt.com/huberman See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Using Light to Improve Health (00:04:31) The Brain-Body Contract (00:05:17) AG1 (Athletic Greens), Thesis, LMNT (00:09:56) Physics of Light, Electromagnetic Energy (00:12:23) Wavelengths of Light (00:15:38) How Light Penetrates Tissues (00:20:13) Light & the Body: Direct & Indirect Signals (00:28:35) Light, Seasonality & Melatonin (00:33:40) Melatonin: Regulatory & Protective Effects (00:38:49) Tools: Optimizing Melatonin Levels (00:44:49) Sun (UVB light) Exposure, Mating Behavior, Testosterone & Estrogen (00:58:09) Seasonality, Romantic Passion & Testosterone (01:02:13) Tool: Skin Sun Exposure & Testosterone (01:06:13) Light & Improved Pain Tolerance (01:11:55) Protocol: Sun Exposure & Chronic Pain (01:12:48) Tools: Sunlight (UVB), Blue-Light Blockers, Seasonal Affective Disorder (SAD) (01:19:44) Light & Enhanced Immune Function (01:23:30) Tool: Light During Winter Months (01:26:18) Light Therapies: Local vs. Systemic Exposure (01:28:54) Tool: Improving Mood, Timing of Natural & Artificial Light (01:32:44) Light Conditions & Sleep Optimization (01:39:00) Infrared Light, Skin & Wound Healing (01:46:00) Infrared Light Therapy & Skin, Low-Level Laser (Light) Therapy (LLLT) (01:49:20) Infrared Light & Age-Related Vision Loss (01:59:36) Tools: Infrared Panels, Morning Exposure (02:05:22) Infrared Light at Night, Shift Work (02:08:35) Light Flicker Phototherapy & Neuroprotection (02:19:07) Phototherapies for Health (02:20:50) Zero-Cost Support, YouTube Feedback, Spotify Reviews, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Neural Network Newsletter, Brain-Body Contract Title Card Photo Credit: Mike Blabac Disclaimer
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Andrew Huberman is a neuroscientist at Stanford and host of the Huberman Lab Podcast. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – LMNT: https://drinkLMNT.com/lex to get free sample pack – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit – MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Andrew’s YouTube: https://youtube.com/AndrewHubermanLab Huberman Lab Podcast: https://hubermanlab.com Andrew’s Twitter: https://twitter.com/hubermanlab Andrew’s Instagram: https://instagram.com/hubermanlab PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: –
BiggerPockets Real Estate Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Inflation and cash flow have been fighting against each other for decades. As soon as you increase the rent on an income property, inflation comes right in to eat some of that gain. So in today’s borderline hyperinflationary environment, is cash flow still coming out on top? A better question to ask may be, what happens in five, ten, or twenty years? Will inflation completely erode your financial freedom dreams? Or will cash flow match (or beat) this destructive force.
This isn’t just a question that impacts real estate investors—it affects almost every individual working within today’s economy. In today’s episode of Seeing Greene, David goes deep into this question (and others) so you, the investors, can have a better understanding of our economy as a whole. You’ll also hear topics like whether or not you can transfer title on an FHA loan, what to do when bidding wars push prices well above market comparables, when to cosign and when to ask for a cosigner, and what every investor in their twenties should start doing today.
Heard a topic that you wanted more explanation on? Want to ask David a question you’ve never heard before? If so, submit your question here so David can answer it on the next episode of Seeing Greene. Hop on the BiggerPockets forums and ask other investors their take, or follow David on Instagram to see when he’s going live so you can hop on a live Q&A and get your question answered on the spot!
In This Episode We Cover:
How spending power changes the way investors calculate cash flow
Transferring title from your personal name into an LLC with an FHA loan
How to know a house is “worth it” and what to look for in a loan officer
Cosigning for a relative to house hack and staying up-to-code with owner-occupied loans
Pivoting markets from a cash flow market to an appreciation market
David’s advice to every young, aspiring real estate investor
And So Much More!
Links from the Show
BiggerPockets Youtube Channel
BiggerPockets Forums
BiggerPockets Pro Membership
BiggerPockets Bookstore
Submit Your Questions to David Greene
BiggerPockets Podcast 567: Seeing Greene: Finding Cash Flow, Refinancing Sooner, & NNN Properties
BiggerPockets Podcast 570: Seeing Greene: Signs of a Great Agent, When to Refi, and How to Scale
BiggerPockets Podcast 571: Is This Deal Worth My Time? The 6 Crucial Steps to Vet a Multifamily Sea
BiggerPockets Podcast 577: Cutting Your Tax Bill, Investing in Different Markets, & “Investor Pressure” | Coaching Calls
BiggerPockets Podcast 582: Seeing Greene: Investing in Paradise, Timing the Market, and House Hacking
BiggerPockets Podcast 585: Seeing Greene: Boosting Your Appraisal, Backward BRRRRs, & Capital Raising Risks
BiggerPockets Podcast 588: Seeing Greene: Climate Change, ADU Dilemmas, & Retiring with Rentals
BiggerPockets Podcast 591: Seeing Greene: The Cash Flow Market “Mirage” That Traps New Investors
David Greene Meetups
David Greene Team
Click here to check the full show notes: https://www.biggerpockets.com/blog/real-estate-594
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health and well-being in both men and women. We discuss how to improve hormones using behavioral, nutritional, and exercise-based tools and safely and rationally approach supplementation and hormone therapies. We discuss testosterone and estrogen and how those hormones relate to fertility, mood, aging, relationships, disease pathologies, thyroid hormone, growth hormone, prolactin, dopamine and peptides that impact physical and mental health and vitality across the lifespan. The episode is rich with scientific mechanisms and tools for people to consider. Thank you to our sponsors Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com - use code "huberman" See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Kyle Gillett, MD, Hormone Optimization (00:03:10) The Brain-Body Contract (00:04:10) Thesis, InsideTracker, ROKA (00:08:24) Preventative Medicine & Hormone Health (00:14:17) The Six Pillars of Hormone Health Optimization (00:17:14) Diet for Hormone Health, Blood Testing (00:20:21) Exercise for Hormone Health (00:21:06) Caloric Restriction, Obesity & Testosterone (00:23:55) Intermittent Fasting, Growth Hormone (GH), IGF-1 (00:29:08) Sleep Quality & Hormones (00:35:03) Testosterone in Women (00:38:55) Dihydrotestosterone (DHT), Hair Loss (00:43:46) DHT in Men and Women, Turmeric/Curcumin, Creatine (00:50:10) 5-Alpha Reductase, Finasteride, Saw Palmetto (00:52:30) Hair loss, DHT, Creatine Monohydrate (00:55:07) Hair Regrowth, Male Pattern Baldness (00:58:12) Polycystic Ovary Syndrome (PCOS), Inositol, DIM (01:04:00) Oral Contraception, Perceived Attractiveness, Fertility (01:10:31) Testosterone & Marijuana or Alcohol (01:14:27) Sleep Supplement Frequency (01:15:34) Testosterone Supplementation & Prostate Cancer (01:20:24) Prostate Health, Dietary Fiber, Saw Palmetto, C-Reactive Protein (01:24:05) Prostate Health & Pelvic Floor, Viagra, Tadalafil (01:30:54) Testosterone Replacement Therapy (TRT) (01:35:17) Estrogen & Aromatase Inhibitors, Calcium D-Glucarate, DIM (01:39:28) Lifestyle Factors to Increase Testosterone/Estrogen Levels, Dietary Fats (01:45:34) Aromatase Supplements: Ecdysterone, Turkesterone (01:47:04) Tongkat Ali (Long Jack), Estrogen/Testosterone levels (01:52:25) Fadogia Agrestis, Luteinizing Hormone (LH), Frequency (01:56:44) Boron, Sex Hormone Binding Globulin (SHBG) (01:58:13) Human Chorionic Gonadotropin (hCG), Fertility (02:04:18) Prolactin & Dopamine, Pituitary Damage (02:08:34) Augmenting Dopamine Levels: Casein, Gluten, Vitamin E, Vitamin B6 (P5P) (02:12:30) L-Carnitine & Fertility, TMAO & Allicin (Garlic) (02:18:19) Blood Test Frequency (02:19:41) Long-Term Relationships & Effects on Hormones (02:25:33) Nesting Instincts: Prolactin, Childbirth & Relationships (02:29:05) Cold & Hot Exposure, Hormones & Fertility (02:32:34) Peptide Hormones: Insulin, Tesamorelin, Ghrelin (02:37:24) Growth Hormone-Releasing Peptides (GHRPs) (02:39:38) BPC-157 & Injury, Dosing Frequency (02:45:23) Uses for Melanotan (02:48:21) Spiritual Health Impact on Mental & Physical Health (02:54:18) Caffeine & Hormones (02:56:19) Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Review, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Brain-Body Contract Title Card Photo Credit: Mike Blabac Disclaimer
The Danny Miranda Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
(0:00) Sahil compliments me
(0:45) Crazy coincidence
(2:40) Sahil’s been plugging his Twitter since 2011
(3:44) Why Sahil is attracted to motivational tracks
(6:31) Obesity research at Nike
(11:40) The transition from arrogance to kindness
(15:25) Identity (Indian + Jewish parents, nerd + jock)
(18:27) 10-year reunion
(20:14) Practices that made Sahil more secure?
(21:39) Darkest hour friend
(25:15) What to say in dark times to a friend?
(27:15) How to accept compliments
(28:08) “I appreciate you”
(30:05) Why Sahil microanalyses life
(32:00) Condoleezza Rice
(36:29) Cold email
(37:38) Going to the gym with Tim Cook
(39:20) Why is Sahil so connected to highly successful people
(46:30) What can someone do today to show grit and work ethic?
(50:02) Zone of genius
(59:15) How to single focus
(1:00:55) More walks without tech
(1:03:10) Connecting with Sahil
Sahil Bloom is an investor, entrepreneur, and creator. In less than 2 years, Sahil has gained over 500,000 Twitter followers. But in this episode, we didn't focus that much on his hyper-growth online. Instead, we spoke about how Sahil got mentored by BOTH Tim Cook and Condoleezza Rice, how Sahil became more secure in himself, and what it means to be a "darkest hour friend."
Sahil's Twitter – https://twitter.com/SahilBloom
Continue the conversation with me...
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Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Rick Rubin is one of the greatest music producers of all time, working with many of the greats including Beastie Boys, Eminem, Metallica, LL Cool J, Kanye West, Slayer, Tom Petty, Johnny Cash, Dixie Chicks, Aerosmith, Adele, Danzig, Red Hot Chili Peppers, System of a Down, Jay-Z, Black Sabbath. Please support this podcast by checking out our sponsors: – Lambda: https://lambdalabs.com/lex – Theragun: https://therabody.com/lex to get 30 day trial – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Onnit: https://lexfridman.com/onnit to get up to 10% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to
ADHD Experts Podcast ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Behaviors like setting unrealistic goals and insisting on personal flawlessness point to a cycle of perfectionism. Join Sharon Saline, Psy.D., to learn more about the relationship between anxiety, perfectionism, and ADHD and how to nurture a growth mindset.
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
I describe mechanisms by which deliberate cold exposure can enhance mental health, physical health, and performance. I detail specific protocols to safely engage in deliberate cold exposure, including minimal exposure times, time-of-day effects, determining optimal temperatures, recovery, mindset, and movement during cold exposure. I discuss how cold exposure can be used to safely stress the body to improve attention, mood, and cognitive focus and boost metabolism and reduce inflammation. Also, I explain how cold exposure on specific regions of the body (called glabrous skin surfaces) can be leveraged to enhance endurance and weight training and increase work output. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://roka.com - use code "huberman" Helix Sleep: https://helixsleep.com/huberman See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Deliberate Cold Exposure, Health Warning (00:04:23) Tool: Moderate Exercise & Cognitive Work (00:10:47) The Brain-Body Contract (00:11:32) AG1 (Athletic Greens), ROKA, Helix Sleep (00:15:37) Circadian Rhythm & Body Temperature (00:18:41) Tool: Quickly Decrease Core Body Temperature, Glabrous Skin (00:25:26) Mental Effects of Cold Exposure (00:29:02) Physical Effects of Cold Exposure (00:30:11) How Cold Should the Temperature Be? (00:34:53) Cold Showers vs. Cold Water Immersion (00:38:27) Protocols for Cold Exposure (00:50:57) Optimal Mindset(s) During Cold Exposure (00:55:26) Tool: Using Movement During Cold Exposure (00:57:51) Optimal Frequency of Cold Exposure (01:00:22) Cold Exposure for Dopamine, Mood & Focus (01:12:55) Cold Exposure & Metabolism, Brown Fat (01:25:55) Tool: Caffeine, Dopamine & Cold Exposure (01:29:14) Tools: Increasing Metabolism w/Cold – The Søberg Principle, Shivering (01:34:15) Norepinephrine & Fat Cells (01:36:22) Cold, Physical Performance, Inflammation (01:47:36) Hyperthermia & Glabrous Skin Cooling (01:53:27) Tool: Palmar Cooling & Endurance (02:03:18) Cold Exposure to Groin, Increasing Testosterone (02:07:50) Tool: Optimal Timing for Daily Cold Exposure (02:11:16) Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Reviews, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer: The Huberman Lab Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Art of Manliness: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Do you ever feel like the time we live in feels flat, complacent, timid, conformist, populated by people who are focused on playing it safe and are inwardly empty?
A century and a half ago, the Danish philosopher Soren Kierkegaard felt the same way about the period in which he lived, and posited that there are two kinds of ages: the revolutionary, decisive, and passionate, and the sensible, rational, and reflective.
Here to unpack Kierkegaard’s ideas on these two kinds of ages is Jacob Howland, retired professor of philosophy and author of Kierkegaard and Socrates. Today on the show, Jacob and I first discuss some background on Kierkegaard and his existential philosophy. We then get into the differences between an age of passion and an age of reflection. We discuss how in a passionate age, an individual stands as an individual, possesses an energy which focuses on truth and ideals, and has the courage to take bold leaps of faith, while in a reflective age, the individual is subsumed by the crowd, is afraid of public opinion, and gets so lost in analysis and abstraction that he never makes a decisive move. All along the way, we delve into how Kierkegaard’s description of his age parallels our own, and Kierkegaard’s evergreen call to be an individual, embrace risk, and own your opinions and actions.
Resources Related to the Podcast Works by Kierkegaard mentioned in the show: + Two Ages: A Literary Review + Either/Or + Fear and Trembling + The Sickness Unto Death + Philosophical Fragments + Concluding Unscientific Postscript on Philosophical Fragments * Thomasine Christine Gyllembourg-Ehrensvärd * Georg Wilhelm Friedrich Hegel * On the Advantage and Disadvantage of History for Life* by Friedrich Nietzsche * “Yes, Sabermetrics Ruined Baseball” * AoM Article: Your Three Selves and How Not to Fall Into Despair * AoM Article: An Intro to Envy * AoM Podcast #635: The Existentialist’s Survival Guide
Connect With Jacob Howland* Jacob’s Website
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Chris Blattman is a professor at the University of Chicago studying the causes and consequences of violence and war. Please support this podcast by checking out our sponsors: – Truebill: https://truebill.com/lex – Mizzen+Main: https://mizzenandmain.com and use code LEX to get $35 off – Grammarly: https://grammarly.com/lex to get 20% off premium – Indeed: https://indeed.com/lex to get $75 credit – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Chris’s Twitter: https://twitter.com/cblatts Chris’s Website: https://chrisblattman.com Why We Fight (book): https://amzn.to/3702fjb PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips:
No Stupid Questions: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Leading neuroscientist and Stanford University School of Medicine professor Dr. Andrew Huberman goes in-depth on how small behaviors can make a huge impact on your health. Dr. Huberman offers essential insights into how light affects your sleep and your energy levels, which supplements actually work, tips to control bad impulses, exercises to slow the aging process, and so much more. Dr. Huberman has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning. Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, given to the scientist making the most significant discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states, such as fear and courage. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
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Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
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Episode Description:
Iñigo San-Millán is an internationally renowned applied physiologist and a previous guest on The Drive. His research and clinical work focuses on exercise-related metabolism, metabolic health, diabetes, cancer metabolism, nutrition, sports performance, and critical care. In this episode, Iñigo describes how his work with Tour de France winner Tadej Pogačar has provided insights into the amazing potential of elite athletes from a performance and metabolic perspective. He speaks specifically about lactate levels, fat oxidation, how carbohydrates in food can affect our lactate and how equal lactate outputs between an athlete and a metabolically unhealthy individual can mean different things. Next, he discusses how Zone 2 training boosts mitochondrial function and impacts longevity. He explains the different metrics for assessing one’s Zone 2 threshold and describes the optimal dose, frequency, duration, and type of exercise for Zone 2. Additionally, he offers his thoughts on how to incorporate high intensity training (Zone 5) to optimize health, as well as the potential of metformin and NAD to boost mitochondrial health. Finally, he discusses insights he’s gathered from studying the mitochondria of long COVID patients in the ICU.
We discuss:
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Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Dr. Andy Galpin, Professor of Kinesiology at California State University, Fullerton, and one of the foremost experts in the world on the science and application of methods to increase strength, hypertrophy and endurance performance. We discuss fundamental principles of strength and hypertrophy training and building endurance, the mechanisms underlying them and we review specific protocols to optimize training and recovery. We also discuss hydration, sleep, nutrition, supplements, and mental tools that can be leveraged to accelerate adaptations leading to enhanced strength, muscle growth and/or endurance. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman InsideTracker: https://insidetracker.com/huberman See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman Huberman Lab Social & Website
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Absolute Rest
For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Andy Galpin, Strength & Endurance Training (00:03:08) The Brain-Body Contract (00:03:55) AG1 (Athletic Greens), Thesis, InsideTracker (00:08:20) Adaptations of Exercise, Progressive Overload (00:14:40) Modifiable Variables, One-Rep Max, Muscle Soreness (00:27:30) Modifiable Variables of Strength Training, Supersets (00:43:50) How to Select Training Frequency: Strength vs. Hypertrophy (00:58:45) Hypertrophy Training, Repetition Ranges, Blood Flow Restriction (01:08:50) Tools: Protocols for Strength Training, the 3 by 5 Concept (01:10:48) Mind-Muscle Connection (01:16:16) Mental Awareness (01:27:57) Breathing Tools for Resistance Training & Post-Training (01:37:25) Endurance Training & Combining with Strength (01:51:20) Tools: Protocols for Endurance Training (02:08:15) Muscular Endurance, Fast vs. Slow Twitch Muscle (02:16:35) Hydration & the Galpin Equation, Sodium, Fasting (02:35:57) Cold Exposure & Training (02:43:15) Heat Exposure & Training (02:53:47) Recovery (03:04:02) Tool: Sodium Bicarbonate (03:17:26) Tool: Creatine Monohydrate (03:20:08) Absolute Rest (03:29:08) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer
Beginner's Mind ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Did you know that almost 90% of all product ideas fail in clinical trials? The most obvious reason that a clinical trial fails is lack of efficacy.
Surprising to me was that lack of efficacy doesn't seem to be the main reason why clinical trials fail in the first place. Other factors are at play, and most of them are manageable risks when the right team is at work.
In this episode, we talk about:
Who is the expert in the show?Heike Schön is the Managing Director and Co-Founder of Lumis International GmbH and Lumis Life Science Consulting GmbH.
She has more than 25 years of experience in leadership positions in international clinical research and drug development.
📞 Book a meeting here: Link
Youtube: https://youtu.be/r0qphO8Qs3o **Shownotes @ Podcastnotes: tbd
Timestamps:**(00:00) Intro
(02:25) Who Is Heike Schön, Lumis International and Lumis Consulting?
(04:20) Topics in the Episode
(04:30) Kick-Off
(05:00) Background to Lumis International and Heike Schön
(10:20) When is the Right Time to Start with the Planning of a Clinical Trial?
(12:10) The Role of a Sponsor of a Clinical Trial
(14:30) Who is Responsible for the Clinical Trial as a Sponsor?
(16:55) When Should a Company Start to Implement Clinical Trial Management in the Organisation?
(18:30) Funding Requirements for Clinical Trials
(20:00) The Reality of Inhouse and Outhouse Clinical Trial Management
(22:15) What to Think About When Planning Oversight Management
(25:00) Relationship and Culture Management in Clinical Trials
(27:25) Budget and Ressource Requirement for Clinical Trials
(28: 45) 3 Steps to a Successful Clinical Trial
(30:40) The 3 Main Reasons Why Clinical Trials Fail
(33:30) Considerations for Patient Enrollment as a Key Success Factor for Clinical Trials
(37:30) … and when enrolment fails, what are the steps to rescue the trial?
(42:45) Do Inhouse Studies Require Rescue?
(44:30) How to Rescue a Clinical Trial
(48:30) Root Cause Analysis as a Starting Point to Rescue a Trial
(52:25) Preventive Measures to Avoid Failure Early on
(53:30) How Important is Leadership in a Clinical Trial?
(56:30) The 3 Main Reasons to Stop a Clinical Trial – The Point of no Return
(59:00) How are the Cost Calculated for Rescue Study Management?
(01:00:15) Planning of a Clinical Trial – A Key Aspect of a Successful Trial
(01:02:15) How to Plan Realistic Timelines and Numbers
(01:07:15) The Role of Feasibility Studies in Clinical Trials
(01:09:30) How Clinical Trial Management Evolved in the last 30 years
(01:11:15) Upcoming Trends in Clinical Trial Management
(01:13:15) Decentralized Clinical Trials
(01:15:00) Artificial Intelligence And Big Data in Clinical Trial Management
(01:17:55) The Digital Twin
(01:19:15) The Human Factor and Leadership in Clinical Trial Management
(01:21:10) The Patient in Clinical Trials
(01:22:55) Planning and its contribution to clinical trial success
(01:26:55) Summary of What to Do When Clinical Trials Fail
(01:28:35) When is the Right Time to Add a Rescue Team to the Clinical Trial?
(01:31:00) A Risk Management Plan for Clinical Trials
(01:32:00) How to Cont
Support the show (https://lsg2g.substack.com/subscribe?)
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
David Friedberg is Founder and CEO of The Production Board (TPB), a holding company established to solve the most fundamental problems that affect our planet, by reimagining global systems of production. Prior to founding The Production Board, David founded The Climate Corporation, a 10-year journey that culminated in their $930M acquisition by Monsanto. If that was not enough, David is the Founder and Chairman at Metromile and also sits on the board of Soylent, Clara Foods, Tillable, Cana Technologies and more.
In Today’s Episode with David Friedberg You Will Learn: 1.) Origins:
2.) The Macro: Venture + The Economy
3.) David Frankel: The Business Builder
4.) David Friedberg: Father and Husband
Item’s Mentioned In Today’s Episode with David Friedberg David’s Favourite Book: Zen Mind, Beginner's Mind
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
I explain how to blunt sugar cravings through fundamental knowledge of how sugar is sensed, metabolized, and utilized within the body. I explain how sugar is processed through the digestive tract and nervous system and how both the taste and nutritive components of sugar can lead to specific appetite changes and cravings. I discuss the connection between sugar, dopamine, and cravings and outline many tools to curb sugar cravings, specifically craving highly processed refined sugars. Thank you to our sponsors Thesis: https://takethesis.com/huberman AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman See Andrew Huberman Live: The Brain Body Contract Tuesday, May 17th: Seattle, WA Wednesday, May 18th: Portland, OR https://hubermanlab.com/tour Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Sugar & Physiology (00:02:25) The Brain-Body Contract (00:03:13) Thesis, AG1 (Athletic Greens), InsideTracker (00:07:40) Sugar & the Brain (00:10:06) Appetite & Hormones: Ghrelin & Insulin (00:14:17) Glucose & Brain Function (00:24:19) Glucose & Physical Activity (00:26:16) Fructose vs. Glucose (00:32:41) When to Eat High-Sugar Foods? (00:35:01) Sugar’s Taste vs. Nutritive Pathways, Sugar Cravings (00:41:46) Tool: Sugar & the Dopamine, Pleasure – Pain Dichotomy (00:48:43) Subconscious Sugar Circuits, Hidden Sugars in Food (00:58:03) Glucose Metabolism in the Brain (01:03:00) Tool: Glycemic Index, Blunting Sugar Cravings (01:12:08) Sugary Drinks, Highly Refined Sugars (01:14:33) Artificial Sweeteners (01:22:36) ADHD, Omega-3s (01:30:18) Tools: Reduce Sugar Cravings with EPA Omega-3s & Glutamine (01:35:15) Tool: Blunt Sugar Peaks & Craving with Lemon Juice (01:43:09) Tool: Reduce Sugar Cravings & Spikes with Cinnamon (01:45:10) Berberine, Sustained Low Blood Glucose Levels (01:51:24) Tool: Sleep & Sugar Cravings (01:56:33) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Patreon, Instagram, Twitter, Thorne, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
The Danny Miranda Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
(0:00) Intro
(2:15) Ice hockey experience
(5:15) What made Dr. Proctor keep going?
(6:00) Meeting Olympian hockey players
(9:25) Getting recognized in public
(11:53) Almost an astronaut
(15:07) Why did Dr. Proctor’s friend suggest she apply to be an astronaut?
(16:29) How do you cultivate curiosity for new technologies?
(18:00) How did Dr. Proctor’s dad help her
(20:07) Why your self-talk is so important
(22:23) Going to Mars?
(24:30) What challenges do we face settling on Mars?
(26:16) Civilians going to space
(28:05) What should we expect on Mars?
(30:40) “Learn to be more forgiving to yourself”
(33:28) Talking to Michelle Obama
(36:58) Starship Earth
(40:49) Where does Dr. Proctor feel accepted?
(41:52) Seeker poem
(44:28) NFTs and saying yes to early technology
(50:39) Exploring the inner world
(55:49) Jack of all opportunities, master of life experience
(56:50) Nickname “Leo”
(1:00:40) Meeting Elon Musk
(1:04:16) Gryffindor
(1:06:37) Is Inspiration4 a family?
(1:08:47) Connecting with Dr. Proctor
Dr. Sian Proctor is an American geology professor, science communicator, and commercial astronaut. She was launched into Earth orbit, on September 15, 2021, as the pilot of the Crew Dragon space capsule.
I originally came across Dr. Proctor when she starred in the Netflix special Countdown: Inspiration4 Mission to Space. In this conversation, we spoke about settling on Mars, getting recognized, and her many talents + interests.
Dr. Proctor's Twitter – https://twitter.com/DrSianProctor
Space2Inspire – https://www.amazon.com/Space2inspire-Inspiration-Dr-Sian-Proctor/dp/1733765417
Continue the conversation with me... 🎙 Podcast: https://podfollow.com/1532160275
🐣 Twitter: https://twitter.com/heydannymiranda
📸 Instagram: https://instagram.com/heydannymiranda
🕺 TikTok: https://tiktok.com/@heydannymiranda
🚨 Newsletter: https://dannymiranda.com/tuesday-treasure/
Rich Roll Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
How does behavior affect your biology? What does neuroscience say about hypnosis, breath work, and meditation? Are behavioral tools more powerful than pharmaceuticals in changing your state and focus?
Today we dig into these big questions and more with neuroplasticity overlord Dr. Andrew Huberman, back for a second, highly anticipated return to the show.
Given that Dr. Huberman’s first appearance on the podcast (RRP #533) has amassed over 10 million views on YouTube alone, chances are you’re already familiar with this tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine, where he runs The Huberman Lab, which studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance.
Subsequent to our first podcast in January of 2021, Andrew launched The Huberman Lab Podcast, which has quickly become a sensation. Within a year of launch, it has ascended to one of the top, most listened to podcasts in the world.
Today we pick up where we last left off, diving deep into a wide array of fascinating topics brimming with actionable takeaways, including:
To read more, click here. You can also watch it all go down on YouTube. And as always, the podcast streams wild and free on Apple Podcasts and Spotify.
Andrew is a passionate man with an incredible facility for communicating complex scientific topics in a uniquely compelling and understanding way.
For those keen on understanding how to better control your mind, neurochemistry, and all told biology—consider this episode appointment listening.
SCIENCE!
Peace + Plants,
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Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Renowned sleep scientist Matthew Walker discusses everything you need to know about what a better night’s sleep can do for your life, and how to prioritize and perfect the way you sleep. Walker breaks down how to identify when you need more sleep, how to deal with insomnia, the best devices to track your sleep, and some unconventional sleep hygiene tips, including why it’s never a good idea to count sheep.
Walker is a Professor of Neuroscience and Psychology at the University of California-Berkeley, and is also the founder and director of the Center for Human Sleep Science. He has published over 100 scientific research studies on the impact of sleep on human brain function, and he is the author of the 2017 book, Why We Sleep: Unlocking the Power of Sleep and Dreams. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/
Follow Shane on Twitter at: https://twitter.com/ShaneAParrish
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss the profound effect the gut has on the nervous system. I cover the structure and function of the gut-brain axis and the role of the gut microbiome in the brain and overall health. I describe how the gut controls hunger or satiety by affecting neurons in our brain. I also contrast the many pathways by which the gut influences the brain: direct vs. indirect pathways, chemical vs. mechanical, and fast vs. slow signaling. Additionally, I discuss what defines a healthy microbiome and how your lifestyle impacts the gut microbiome, including the effects of stress, fasting, antibiotics, pets, environment, prebiotics and probiotics. I address how different foods shape the gut microbiome, in particular, the emerging data that fermented foods can increase the diversity of healthy gut microbiota. Throughout the episode, I explain peer-reviewed and textbook findings that reveal the critical role of the gut microbiome in supporting mental and physical health and I outline simple tools that anyone can use in order to enhance their gut microbiome health. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman InsideTracker: https://insidetracker.com/huberman Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman Social & Website
YouTube
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Article Links
"The Emerging Biology of Gut-Brain Sensory Transduction"
"Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder"
"Association of Loneliness and Wisdom With Gut Microbial Diversity and Composition: An Exploratory Study"
"Emotional well-being and gut microbiome profiles by enterotype"
"Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis"
"Gut-microbiota-targeted diets modulate human immune status"
"The preference for sugar over sweetener depends on a gut sensor cell"
Book Links "The 4-Hour Chef: The Simple Path to Cooking Like a Pro, Learning Anything and Living the Good Life" Timestamps (00:00:00) Gut Microbiome (00:03:02) AG1 (Athletic Greens), LMNT, InsideTracker (00:06:55) Your Gut-Brain Axis (00:09:44) Gut-Brain Anatomy (00:15:32) Microbiota vs. Gut Microbiome (00:20:01) Roles of Gut Microbiome (00:23:03) Neuropod Cells: (Subconscious) Tasting with Your Stomach (00:34:13) Ghrelin: Slow Modulation of Your Brain in Hunger (00:38:02) Glucagon Like Peptide 1; GLP-1 (00:42:22) Tools: ‘Free Will’ & Food Cravings (00:44:46) Mechanical Cues from Gut to Brain (00:49:05) Dopamines, Vomiting (00:52:06) Indirect Signals from Gut Microbiota (00:59:30) Gut Microbiome “Critical Periods” (01:03:08) How Gut Health Controls Overall Health (01:12:25) What is a Healthy Gut Microbiome? (01:15:00) Tools: Enhance Your Gut Microbiome (01:23:49) Foods to Enhance Microbiota Diversity; Fermented Foods (01:37:07) High-Fiber Diets & Inflammation (01:40:58) Artificial & Non-Caloric Sweeteners (01:44:27) Structure & Function of Gut-Brain Axis (01:49:47) Zero-Cost Support, YouTube, Spotify, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer
Starting Greatness with Mike Maples: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Your startup will face multiple WFIO moments on the path to greatness...COUNT ON IT. But that doesn’t mean you should let these moments get inside your head. In this lesson of greatness, Mike Maples, Jr of FLOODGATE discusses how every startup team MUST be prepared to take the initiative in the crucible of the WFIO moments they will inevitably face. The bright side? You can use these horrible situations as defining moments to show everyone that your startup is destined to defeat the impossible.
Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Mark Zuckerberg is CEO of Meta, formerly Facebook. Please support this podcast by checking out our sponsors: – Paperspace: https://gradient.run/lex to get $15 credit – Coinbase: https://coinbase.com/lex to get $5 in free Bitcoin – InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Mark’s Facebook: https://facebook.com/zuck Mark’s Instagram: https://instagram.com/zuck Meta AI: https://ai.facebook.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT &
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Dr. David Spiegel MD, Associate Chair of Psychiatry & Behavioral Sciences, Director of the Center on Stress and Health and Director of the Center for Integrative Medicine at Stanford University School of Medicine. Dr. Spiegel has more than 40 years of clinical and research experience with hypnosis, stress physiology, and psychotherapy. In this episode, we examine the role of clinical hypnosis for the treatment of trauma, chronic pain, anxiety and more. Dr. Spiegel explains how to determine your level of ‘hypnotizability’ and provides case studies of incredible successes with hypnosis to treat a variety of ailments. We also discuss how breathing, vision and directed mental focus can modulate internal states and enhance performance. Additionally, we discuss how the adoption of self-hypnosis techniques can reduce stress and enhance sleep in anyone. Dr. Spiegel teaches us how hypnosis works at the neural circuit level to enhance cognitive flexibility. Throughout the episode, Dr. Spiegel summarizes key clinical trials and peer-reviewed findings and resources to work with a trained clinical professional or to do guided self-hypnosis. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Thesis: https://takethesis.com/huberman ROKA - https://roka.com - code "huberman" Our Patreon page https://www.patreon.com/andrewhuberman Supplements from Thorne https://www.thorne.com/u/huberman Huberman Lab Social & Website
YouTube
Website
Newsletter
Dr. David Spiegel Links
Stanford Center for Stress and Health
Support Dr. Spiegel’s Research at Stanford (tax-deductible)
Dr. Spiegel’s Published Work
Email: david@reveri.com
Article Links
Posthypnotic Amnesia in Hypnotizability Assessment: Validation of a New Scoring System for the Hypnotic Induction Profile
Post-traumatic stress disorder and cancer
Association between Anterior Cingulate Neurochemical Concentration and Individual Differences in Hypnotizability
Hypnosis reduces distress and duration of an invasive medical procedure for children
Other Links
Society for Clinical and Experimental Hypnosis
American Society for Clinical Hypnosis
Watch Andrew’s Hypnosis Session with Dr. Spiegel
Reveri website
Reveri app (iOS)
Join the Waitlist for Reveri for Android
Timestamps (00:00:00) Dr. David Spiegel MD, Hypnosis (00:04:16) AG1 (Athletic Greens), Thesis, ROKA (00:09:09) Clinical Hypnosis (00:16:45) Stage Hypnosis (00:20:25) Neurobiology of Hypnosis (00:26:04) ADHD (00:28:22) Hypnosis for Stress & Sleep (00:32:12) Hypnosis to Strengthen Neural Connections (00:37:19) Restructuring Trauma Narratives (00:45:14) Ketamine Therapy (00:50:07) Self-directed Hypnosis, Reveri (00:56:53) Eliminating Obsessive Thoughts, Superstitions (01:01:50) ‘Hypnotizability’, the Spiegel Eye-roll Test (01:15:36) EMDR (Eye Movement Desensitization Reprocessing) (01:21:43) Confronting Stress & Trauma (01:27:56) The Mind-Body Connection (01:31:35) Dealing with Grief (01:35:45) Hypnosis in Children & Groups (01:40:06) Drug Therapies & Hypnosis (01:42:39) Breathing Patterns, Peak Performance (01:50:00) Zero-Cost Support, YouTube, Spotify & Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer
Modern Wisdom: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Daniel Pink is a psychologist, speaker and an author.
Regret is the most common negative emotion humans talk about. It's even the second most common overall emotion which we talk about after love. And yet our relationship with it is pretty terrible. Having no regrets is not only a bad tattoo from the 90's but also a philosophy that robs of us valuable insights from life.
Expect to learn the most common types of regrets people have in life, whether action or inaction is the cause of most suffering, how Daniel suggests we can grow past our regrets, why never looking backward is limiting our growth, how people believe in both free will and things happening for a reason and much more...
Sponsors:
Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/
Get 15% discount on Craftd London’s jewellery at https://bit.ly/cdwisdom (use code MW15)
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Extra Stuff:
Buy The Power Of Regret - https://amzn.to/3I0UUx9
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Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/
To support me on Patreon (thank you): https://www.patreon.com/modernwisdom
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Get in touch.
Instagram: https://www.instagram.com/chriswillx
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Email: https://chriswillx.com/contact/
The Fantastic History Of Food: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Onions have been a part of human history since long before records began. It's played a vital part in our diets, but also in our mythology, representing eternal life to some cultures, as well as playing a part in the origin stories of the stars. Onions are one of natures most versatile products and in this episode we dive deep into the role it's played throughout the ages.
Please support me on Patreon: https://www.patreon.com/foodhistorypod and get early access to episodes, and bonus content.
Find transcripts and sources on the website: www.foodhistorypodcast.com
The Marie Forleo Podcast ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Could an episode of The Marie Forleo Podcast save your life? This one might. Tony shares about his new book “Life Force,” including his life-changing health journey from devastating diagnosis to peak performance, and the mind-blowing health breakthroughs he’s learned from 100+ of the world’s top medical minds. If you want to maximize your energy, prevent disease, and even REVERSE your aging, this episode is for you.
Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.
In this episode, Dr. Elinav and I discuss...
Get the show notes: https://www.foundmyfitness.com/episodes/eran-elinav Looking for more?Join over 300,000 people and get the latest distilled information on sleep, depression, and fasting straight to your inbox weekly: https://www.foundmyfitness.com/newsletter
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Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Aaron Levie is the Founder and CEO @ Box, the company incorporating the best of secure content collaboration with an intuitive user experience suited to the way people work today. Prior to their IPO in 2015, Aaron raised from some of the best in the business including the main man Mark Cuban, a16z, Emergence, DST, Coatue, DFJ and many more. Aaron founded the company from his dorm room at the University of Southern California and has led the company to 1,900 employees and over $770M in revenue, as of 2021 data.
In Today’s Episode with Aaron Levie You Will Learn: 1.) How Aaron founded Box from his dorm room at the University of Southern California? What was that founding a-ha moment? What did the first year look like? Does Aaron agree, "serial entrepreneurship is overrated"?
2.) Phases of Leadership and Company Growth:
3.) The Market:
4.) The Team and Culture:
Item’s Mentioned In Today’s Episode with Aaron Levie Aaron’s Favourite Book: Innovator's Dilemma: When New Technologies Cause Great Firms to Fail (Management of Innovation and Change)
Venture Stories: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Today’s guest is Ben Braverman. Ben is currently Chief Customer Officer at Flexport after 6 years of being their Chief Revenue Officer during Flexport’s hypergrowth period.
In this episode, we discussed how to build a good sales machine from the ground up. Ben also shares his thoughts on all things revenue - from marketing to BD to forming early SDR teams.
On Deck and Flexport are co-building the future of logistics — learn more about their joint accelerator at www.beondeck.com/x/flexport.
Adam Gelman, On Deck’s Head of Go-To-Market, joined Erik in this episode as a guest co-host. We hope you enjoy.
___
Execs is a show for founders, operators, and pioneers who want to understand the playbooks, frameworks, and tactics that leading tech companies today have used to scale. We will be simulcasting the podcast on the Village Global feed.
Share your thoughts with us on Twitter:
Hosted by: @eriktorenberg
Guest: @braveben
Guest co-host: @Adam_Gelman
Produced by: @jacksonsteger
Brought to you by: @beondeck
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
My guest is Dr. Alia Crum, Associate (tenured) Professor of Psychology at Stanford University and Director of the Stanford Mind & Body Lab. Dr. Crum is a world expert on mindsets and beliefs and how they shape our responses to stress, exercise, and even to the foods we eat. We discuss how our mindset about the nutritional content of food changes whether it is satisfying to us at a physiological (hormonal and metabolic) level. She also tells how mindsets about exercise can dramatically alter the effects of exercise on weight loss, blood pressure, and other health metrics. Dr. Crum teaches us how to think about stress in ways that allow stress to grow us and bring out our best rather than diminish our health and performance. Throughout the episode, Dr. Crum provides descriptions of high-quality peer-reviewed scientific findings that we can all leverage toward better health and performance in our lives.
Thank you to our sponsors
Thesis - https://takethesis.com/huberman
ROKA - https://roka.com - code "huberman"
InsideTracker - https://insidetracker.com/huberman
Dr. Alia Crum Links
Stanford Mind & Body Lab
Support Dr. Crum’s research at Stanford (tax-deductible)
Dr. Crum’s published work
Our Patreon page: https://www.patreon.com/andrewhuberman
Supplements from Thorne: https://www.thorne.com/u/huberman
Huberman Lab Social
Website
Newsletter
Links
Toolkit for changing stress mindsets
Publication on mindsets & side effects
Changing patient mindsets about non-life-threatening symptoms during oral immunotherapy
Stress, mindsets, and success in Navy SEALs special warfare training
Nutritional analysis of foods and beverages depicted in top-grossing US movies, 1994-2018
Nutritional Analysis of Foods and Beverages Posted in Instagram Accounts of Highly Followed Celebrities
Timestamps
(00:00:00) Introducing Dr. Alia Crum from Stanford University
(00:03:15) Thesis, ROKA, Inside Tracker
(00:08:26) What Is a Mindset & What Does It Do?
(00:14:45) Mindsets Change Our Biological Responses to Food
(00:22:28) Beliefs About Our Food Matter
(00:25:57) Placebo vs Beliefs vs Nocebo Effects
(00:28:57) Mindset (Dramatically) Impacts the Effects of Exercise
(00:33:44) Motivational Messaging & Mindset About Fitness
(00:39:30) The Power of a ‘Potency & Indulgence’ Mindset
(00:42:03) Mindsets About Sleep, Tracking Sleep
(00:45:00) Making Stress Work For (or Against) You
(01:01:50) Mindsets Link Our Conscious & Subconscious
(01:04:50) 3 Best Ways to Leverage Stress
(01:10:40) 4 Things That Shape Mindsets, Influencers & Mindsets
(01:19:40) Mindsets About Medicines & Side Effects
(01:26:25) How to Teach Mindsets
(01:31:47) Dr. Crum’s Research, Clinical & Athletic Backgrounds
(01:36:20) The Stanford Mind & Body Lab, Resources for Stress
(01:38:30) Synthesis, Participating in Research
(01:39:04) Subscribe, Sponsors, Patreon, Instagram, Twitter, Thorne
Title Card Photo Credit: Mike Blabac
Disclaimer
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss the transformative nature of play—how it changes our feelings, thoughts and actions and indeed, how it can rewire our brain to function better in all contexts. I explain the role of play in childhood, as well as adulthood in skill and social development and describe key characteristics of the mind and body during play. Additionally, I explore how play allows the brain to test contingencies in different roles/environments. Throughout, I discuss the underlying neurobiology of play. I also describe how low-stakes play, and tinkering can broaden and shape your future capabilities. Finally, I discuss how our childhood ‘personal play identity’ informs our adult personality. Throughout the episode, I use the science of play to outline recommendations for using play as a means to enhance neuroplasticity and explore novel situations, regardless of age.
Thank you to our sponsors AG1 (Athletic Greens) - https://www.athleticgreens.com/huberman ROKA - https://www.roka.com - code "huberman" Helix Sleep: http://helixsleep.com/huberman
Our Patreon page: https://www.patreon.com/andrewhuberman
Supplements from Thorne: https://www.thorne.com/u/huberman
Social & Website Instagram - https://www.instagram.com/hubermanlab Twitter - https://twitter.com/hubermanlab Facebook - https://www.facebook.com/hubermanlab Website - https://hubermanlab.com Newsletter - https://hubermanlab.com/neural-network
Article Links
Reading on a smartphone affects sigh generation, brain activity, and comprehension
In search of the neurobiological substrates for social playfulness in mammalian brains
Is chess just a game, or is it a mirror that reflects the child's inner world?
A new structural model for the study of adult playfulness: Assessment and exploration of an understudied individual differences variable
5MinuteConsult Journal Club
Book Links
Personal play identity and the fundamental elements in its development process
Spark: The Revolutionary New Science of Exercise and the Brain
Play It Away: A Workaholic’s Cure for Anxiety
Timestamps (00:00:00) The Power of Play (00:02:23) Tool: Reading on Smart Phones, Sighing & Learning (00:09:14) AG1 (Athletic Greens), Roka, Helix Sleep (00:13:57) Homeostatic Regulation of Play (00:23:53) Childhood Play & Mindsets (00:29:21) Contingency Testing (00:32:17) The (Power of) Playful Mindset (00:36:13) Body Postures (00:44:03) Rule Testing & Breaking (00:48:24) Role Play (00:50:39) Neurobiology of Low-stakes Play (00:54:22) Expanding Capabilities through Tinkering (01:00:03) Play Is THE Portal to Neuroplasticity (01:04:44) Adulthood Play (01:10:14) Fire Together, Wire Together (01:18:03) Trauma & Play Deficits & Recovery (01:23:25) Competition & Dynamic Movement (01:27:36) Chess, Mental Roles, Novelty (01:32:52) Personal Play Identity (01:37:24) Play Transforms Your Future Self (01:40:55) Recommendations for Play (01:44:25) Zero-Cost Support, Spotify/Apple Reviews, YouTube, Sponsors, Patreon, Instagram, Twitter, Thorne
Title Card Photo Credit: Mike Blabac
Disclaimer
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 Stupid vs. Evil (21st Century Journalism)
00:09:16 The No Handshake Policy
00:10:50 The Centralization Inherent to Traditional Media
00:14:14 “The Monopoly of Truth is Effectively the Monopoly on Violence”
00:18:18 The Journalistic Incentive to Incite Conflict
00:21:09 Once Upon a Time, Google was a Neutral Search Engine
00:24:12 The Prevalence of Foreign-Made Goods to US Lifestyles
00:30:10 The More One Resorts to Coercion, the Less Firm One’s Hold on Power
00:33:58 The Rising Empire of China
00:40:01 The Chinese Anti-Corruption Model
00:42:54 NYDIG
00:44:01 The Secret Document that Transformed China
00:49:38 The Hierarchal Management Model of China
00:54:19 “Social Media Basically Defines Celebrity Today”
00:57:37 “If It Bleeds It Leads”: The Broken Incentives of Journalism
01:05:37 Digital Content Becoming a Goal-Oriented Set of Stimuli?
01:10:29 Reforming Legacy Journalism
01:12:37 The Rise of “Wokism” and the Collapse of Legacy Journalism
01:18:39 Centralized Media Companies as Bottlenecks to Truth-Discovery
01:24:44 Reintroducing Entrepreneurship to Journalism via Decentralization
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom.
Related Links/Products Mentioned
People Mentioned
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Silicon Valley icon Marc Andreessen explores investing, decision making, and the art of solving unsolvable problems. In this discussion, Andreessen reveals why the Internet has become the conduit for some people to disrupt traditional power structures and for others to enforce them, optimistic and pessimistic scenarios for the future of the Internet, assessing judgment, and the book he turns to for insight. Andreessen is a co-founder and general partner at the venture-capital firm Andreessen Horowitz, and has invested in companies such as Facebook, Pinterest, Twitter and Skype, among others. He co-created the highly influential Mosaic internet browser and co-founded Netscape, and has been named one of the 100 most influential people in the world by Time. The books recommended by Marc Andreessen in this episode are: * The WEIRDest People in the World, by Joseph Henrich * The Machiavellians: Defenders of Freedom, by James Burnham * The Revolt of The Public and the Crisis of Authority in the New Millennium, by Martin Gurri * The Ancient City, by Numa Denis Fustel De Coulanges
--
Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/
Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/
Follow Shane on Twitter at: https://twitter.com/ShaneAParrish
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 Quantifying Decentralization
00:07:30 Fundamentally, this Model is Quantifying Intuition…
00:14:39 The Goal: Identifying the Most Centralized Component
00:17:20 The Role of Path-Dependence in Decentralization
00:20:00 The Danger of Monoculture
00:25:00 “Trust in God But Keep Your Powder Dry”
00:32:29 Chain Interoperability and an Attack on Bitcoin Mining
00:34:20 Entering the Time of Total Cyberwar
00:37:32 NYDIG
00:38:42 Incentive Blindness
00:44:42 “The Dose Makes the Poison”
00:48:01 Quantity and Quality Metrics
00:51:16 “Revolutions are Judged by their Fruits”
00:57:23 The Pragmatic Calculation of Self-Interest
01:02:56 Legacy Journalism Disabled the Our Early Warning System
01:08:30 The Most Important Ethical Question of the 21st Century
01:11:26 What Drives Balaji? And Where is the World Going Next?
01:17:57 Mathematical Advancement as the Primary Metric for Civilization
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 Wargaming: East vs. West
00:08:48 A Potential Restructuring of Geopolitical Power
00:12:58 “The Bitcoin Seizure Bill” of the Late-2020s?
00:16:52 A Scenario Where Both CCP and BTC Win
00:19:31 The Fragmentation of Sovereignty in The West
00:22:50 “Three New Deals”: China as the 21st Century Exception
00:26:34 Defense of The Decentralized West vs. The Centralized East
00:30:03 An Optimalist Operates with a Limiting Principle
00:32:31 Bitcoin Breaks All Incompetent States
00:36:23 Looking Deeper into the Coming Centralized vs. Decentralized Struggle…
00:40:38 Decentralization and the Disorganization of Violence
00:45:12 “When there is Anarchy, People Want Leadership”
00:48:20 Human Root Access: The Moral Justifications of Action
00:53:52 China Without the US-Check On It is a Whole Different Animal
00:56:13 Will All Software Backends Go “Blockchain” Eventually?
01:03:17 Re-Bundling Civilization into Sovereign Collectives
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss ways to set up your workspace to optimize productivity, focus and creativity. I discuss how to adjust light, physically arrange your work environment, and leverage body posture to enhance productivity. Additionally, I explore how to shift your work environment for particular types of tasks. Moreover, I review the role of body movement in the workspace. I also discuss sound-based tools that can either enhance or diminish cognitive functioning (the ability to focus on deep work). I describe a particular frequency of binaural beats that studies show can be used to enhance memory and recall. This episode covers quality peer-reviewed findings practical tools anyone can use, regardless of budget, in order to optimize their workspace to achieve heightened levels of productivity, increased alertness and focus, and creativity.
Thank you to our sponsors
LMNT: https://www.drinkLMNT.com/huberman
AG1 (Athletic Greens): https://www.athleticgreens.com/huberman
Theragun: https://theragun.com/huberman
Our Patreon https://www.patreon.com/andrewhuberman
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Social & Website
Website
Newsletter
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The Influence of Ceiling Height
Heating, Ventilation, & AC Noise During Mental Work
Office Noise & Employee Concentration
Effects of a Workplace Sit-Stand Desk Intervention on Health & Productivity
Effects of Binaural & Monaural Beats on Attention
40-Hz Binaural Beats Enhance Training to Mitigate the Attentional Blink
Timestamps
(00:00:00) Arranging Environment for Focus
(00:02:40) LMNT, AG1 (Athletic Greens), Theragun
(00:07:55) How to Increase Focus
(00:10:02) Lighting Your Work in Phase 1
(00:16:00) Lighting Your Work in Phase 2
(00:19:45) Lighting Your Work in Phase 3
(00:24:17) Where to Look While You Work
(00:28:02) Arranging Your Environment
(00:31:24) Body Posture
(00:34:22) How Long to Do Deep Work
(00:36:50) Set the Right Visual Window Size
(00:42:15) 45 min / 5 min Rule
(00:44:23) The Cathedral Effect: Analytic vs Creative Work
(00:55:50) Leveraging Background Noise
(01:02:20) Binaural Beats for Work
(01:06:38) The Best Binaural Frequency for Work
(01:11:17) How Binaural Beats Increase Focus
(01:13:56) Minimizing Interruptions
(01:20:01) Sit or Stand, or Both?
(01:25:18) Movement in the Workspace
(01:31:00) Summary & Shifting Work Environments
(01:39:36) Zero-Cost Support, Sponsors, Patreon, Instagram, Twitter, Thorne
Title Card Photo Credit: Mike Blabac
Disclaimer
Pomp Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Luke Burgis is the Author of "Wanting: The Power of Mimetic Desire in Everyday Life" and writes the "Anti-Memetic" Newsletter.
Circle is a global financial technology firm that enables businesses of all sizes to harness the power of stablecoins and public blockchains for payments, commerce and financial applications worldwide. Circle is also a principal developer of USD Coin (USDC), the fastest growing, fully reserved and regulated dollar stablecoin in the world. The free Circle Account and suite of platform API services bridge the gap between traditional payments and crypto for trading, DeFi, and NFT marketplaces. Create seamless, user-friendly, mainstream customer experiences with crypto-native infrastructure under the hood with Circle. Learn more at circle.com.
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 The “Glorious Purpose” of Property Protection
00:06:36 NYT, CCP, and Woke Capital
00:12:00 Sovereignty vs. Self-Sufficiency
00:16:02 “Religious Fundamentalism Isn’t Always Pretty”
00:19:38 NYDIG
00:20:46 Cultural “Horizontal Gene Transfer”
00:22:53 The Ideological Virality of Communism in History
00:27:07 A Stable State of Combined Moral Justification and Raw Power
00:29:58 The Dangers of an “Inclusive” Ideology
00:32:42 Rigid Hierarchies Hurting Human Cooperation
00:36:32 “The Decentralized Center”
00:38:47 The Whitewashing of Communism in History
00:40:52 The Nepotism of NYT
00:43:25 Favor-Trading
00:45:36 Zuckerberg as an Entrepreneur
00:47:51 Euphemism and Dysphemism
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 What Happens When the US Military Fails?
00:07:55 The Dangers of Administrative Mimicry
00:11:50 The Maginot Line
00:16:57 Social Cohesion and Mutual Trust
00:17:25 NYDIG
00:18:33 The Public Defeat of the US in Afghanistan
00:24:31 Slogans: “Battle Cries of the Dead”
00:28:52 The “Cope” of the US Military Post-Afghanistan Retreat
00:35:10 “What are you a Patriot Towards, and a Customer Of?”
00:39:20 The Co-Evolution of Creator and Creation
00:43:37 The Levels of Living of Libertarianism
00:47:39 The Overwhelming Value of the Division of Labor
00:50:33 “The Great Resignation Will Trigger the Great Automation”
00:54:10 The Berlin Wall Was Built to Keep Taxpayers In
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Infinite Loops we have Sahil Lavingia with us. Sahil is the founder and CEO of Gumroad, and author of the book “The Minimalist Entrepreneur”.
Follow Sahil on Twitter at https://twitter.com/shl and buy his book from Amazon at amzn.to/2ZnIGOl
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 Defining Sovereignty in The Digital Age
00:07:00 Property Rights and Individual Sovereignty
00:10:41 Examples of Market Failure
00:14:29 Externalities: Construction Shadows and Warfare
00:17:00 The Non-Aggression Principle vs. The Aggression Principle
00:21:19 Tribalism and The Principle of “No Internal First Strike”
00:27:25 NYDIG
00:28:33 The Importance of Defensive Technologies to Peace
00:33:08 The Nation-State is Born from Natality
00:38:52 The Homeless Problem is Not a Housing Problem
00:42:00 The Future: A Centralized East and Decentralized West?
00:47:41 A Transition from “The USA” to “America”
00:51:10 Bitcoin: A Force of Supranational Sovereignty
00:55:16 Chesterton’s Fence and Price Stability
00:59:02 Order Books, Price Makers, and Price Takers
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
The "What is Money?" Show ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Balaji Srinivasan joins me for a multi-episode series exploring sovereignty in The Digital Age, geopolitical game theory, the future of statism, and how Bitcoin/crypto fits into the picture.
Be sure to check out NYDIG, one of the most important companies in Bitcoin: https://nydig.com/
GUEST
Balaji's Twitter: https://twitter.com/balajis
Balaji's Website: https://balajis.com/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
RSS Feed: https://feeds.simplecast.com/MLdpYXYI
Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 The Future of a “Price Stable” Fiat Currency
00:04:24 The Future of On-Chain Automation
00:08:30 Bitcoin as Point “Zero, Zero” of Global Digital Economy
00:11:22 The Geopolitical Thesis, Antithesis, and Synthesis of Bitcoin
00:15:32 The Lindy Effect, Bitcoin, and Technological Disruption
00:19:13 Will Other Forms of Property Become Digitized?
00:22:14 Bitcoin is Both for Power Users and the Marginalized Users
00:25:25 NYDIG
00:26:32 The Polarity of Adoption for Bitcoin and Digital Securities
00:30:44 Satoshi Nakamoto was Not a Bitcoin Maximalist
00:34:43 Bitcoin’s Path Toward Global Dominance
00:37:08 Antiquated Securities Laws and Social Scalability
00:41:55 Holding the Principle Above the Implementation
00:48:57 “There’s Nothing So Good That You Can’t Overdo It”
00:52:54 Champagne Socialism is the Only Kind of Socialism
00:57:06 Transhumanism vs. Anarcho-Primitivism
01:03:13 The History of Maoism and How China Got Rich
01:11:14 In Communist China, Entrepreneurship was Punishable by Death
SOCIAL
Breedlove Twitter: https://twitter.com/Breedlove22
WiM? Twitter: https://twitter.com/WhatisMoneyShow
LinkedIn: https://www.linkedin.com/in/breedlove22/
Instagram: https://www.instagram.com/breedlove_22/
TikTok: https://www.tiktok.com/@breedlove22?lang=en
All My Current Work: https://linktr.ee/breedlove22
WRITTEN WORK
Medium: https://breedlove22.medium.com/
Substack: https://breedlove22.substack.com/
WAYS TO CONTRIBUTE
Bitcoin: 3D1gfxKZKMtfWaD1bkwiR6JsDzu6e9bZQ7
Sats via Strike: https://strike.me/breedlove22
Sats via Tippin.me: https://tippin.me/@Breedlove22
Dollars via Paypal: https://www.paypal.com/paypalme/RBreedlove
Dollars via Venmo: https://venmo.com/code?user_id=1784359925317632528
The "What is Money?" Show Patreon Page: https://www.patreon.com/user?u=32843101&fan_landing=true
RECOMMENDED BUSINESSES
Worldclass Bitcoin Financial Services: https://nydig.com/
Join Me At Bitcoin 2022 (10% off if paying with fiat, or discount code BREEDLOVE for Bitcoin): https://www.tixr.com/groups/bitcoinconference/events/bitcoin-2022-26217
Automatic Recurring Bitcoin Buying: https://www.swanbitcoin.com/breedlove/
Buy Bitcoin in a Tax-Advantaged Account: https://www.daim.io/robert-breedlove/
Home Delivered Organic Grass-Fed Beef (Spend $159+ for 4 lbs. free): https://truorganicbeef.com/discount/BREEDLOVE22
Buy Your Dream Home without Selling Your Bitcoin with Ledn: https://ledn.io/en/?utm_source=breedlove&utm_medium=email+&utm_campaign=substack
Philosophize This!: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Today we talk about a famous book from the work of Karl Popper.
The Prof G Pod with Scott Galloway: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Mike Novogratz, the founder and CEO of Galaxy Digital, an investment firm focused on cryptocurrencies, blockchain technology, and digital assets, joins Scott to give us a macro view of the crypto space. He tells us about the various use cases of Bitcoin, Ethereum, and NFTs as well as how to think about investing in them. Follow Mike on Twitter, @novogratz. Scott opens with his thoughts on conglomerates and offers a prediction for 2022. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I discuss the science of setting, assessing, and pursuing goals. I explain the neural (brain) circuits that underlie goal setting and pursuit. Then I describe nine science-supported tools anyone can apply toward their goals. I explain when and how to use goal visualization, when to use multitasking and how to use specific rewards to improve the likelihood of reaching your goals. I also explain why envisioning failures and their consequences are effective and how to set goals of the appropriate level of challenge. I also explain how the molecule dopamine is used to gauge our progress toward milestones and long-term overarching goals and how to leverage dopamine for goal pursuit. Finally, I explain a unique tool called 'space-time bridging' that can be used to support all aspects of goal setting, assessment, and pursuit. This episode ought to be useful for anyone seeking to improve their performance in work, school, exercise, athletics, or personal development.
Thank you to our sponsors:
Our Patreon page:
Supplements from Thorne:
Social:
Links:
Timestamps:
Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
This episode my guest is Dr. Jack Feldman, Distinguished Professor of Neurobiology at University of California, Los Angeles and a pioneering world expert in the science of respiration (breathing). We discuss how and why humans breathe the way we do, the function of the diaphragm and how it serves to increase oxygenation of the brain and body. We discuss how breathing influences mental state, fear, memory, reaction time, and more. And we discuss specific breathing protocols such as box-breathing, cyclic hyperventilation (similar to Wim Hof breathing), nasal versus mouth breathing, unilateral breathing, and how these each effect the brain and body. We discuss physiological sighs, peptides expressed by specific neurons controlling breathing, and magnesium compounds that can improve cognitive ability and how they work. This conversation serves as a sort of "Master Class" on the science of breathing and breathing related tools for health and performance. Thank you to our sponsors:
Our Breath Collective:
Dr. Jack Feldman Links:
Our Patreon page:
Supplements from Thorne:
Social:
Timestamps:
Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Mark Carney is Vice Chair of Brookfield Asset Management and Head of Transition Investing. Prior to Brookfield, Mark served as the Governor of the Bank of England from 2013 to 2020, and prior to that as Governor of the Bank of Canada from 2008 until 2013. Mark was also Chairman of the Financial Stability Board from 2011 to 2018. Mark is a long-time and well-known advocate for sustainability and is currently the United Nations Special Envoy for Climate Action and Finance. If that was not enough, Mark serves on numerous other boards including Stripe, Bloomberg Philanthropies and the Foundation Board of the World Economic Forum to name a few.
In Today’s Episode with Mark Carney You Will Learn: 1.) How Mark made his entrance into the world of finance and came to the role of Governor of the Bank of Canada? How did that role lead to his becoming Governor of the Bank of England? How did seeing multiple booms and busts impact Mark's investing mindset?
2.) Governments, Central Banks and Regulation:
3.) The Winners and Losers:
4.) The Future of NFTs:
Item’s Mentioned In Today’s Episode with Mark Carney Mark’s Favourite Book: Arcadia by Tom Stoppard
Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode, I review the science of habit formation and habit elimination and how the process of neuroplasticity (brain rewiring) underlies these processes.
I describe two new systems for habit formation. The first system is grounded in the neuroscience of brain states and our ability to perform (and to avoid) certain tasks at different phases of the 24-hour day. The second system focuses on 21-day habit formation and consolidation.
I also discuss "task bracketing" as an approach to enhancing habit formation and eliminating unwanted habits and the neural circuits that underlie task bracketing in the basal ganglia (a brain region for generating and stopping behaviors). I also review the science of dopamine rewards and how to apply that knowledge to shaping habits.
The science and tools in this episode ought to be helpful for anyone looking to build better habits and eliminate unwanted habits for school, work, fitness, relationships, creative endeavors, and more—indeed for any person or situation where behavioral changes are needed. Thank you to our sponsors:
Our Patreon page:
Supplements from Thorne:
Social:
Links:
Timestamps:
Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com
Into the Impossible With Brian Keating: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
It's been a phenomenal year for some folks; a tough year for others. Join us live to review the year that was and look forward to 2022 too! A wide-ranging, fun, free for all conversation with my friend Eric Weinstein!
00:00 Topics:
05:00 Eric and Project Galileo investigating UFO/UAP
30:00 Woit's TOE as discussed with @Lex Fridman https://youtu.be/nDDJFvuFXdc
Geometric Unity and Chern-Simons
45:00 Wolfram Physics Project
1:00:00 Raising kids to succeed in STEM
Opportunities and Threats to our future
Thoughts on Bitcoin/Blockchain/NFT for science
Brian's Assayer Project
Maxwell Trial
Covid-19
2:00:00 Should Eric Revive the Portal?
Get us gifts: Please subscribe to my YouTube Channel, just click here 👉 https://www.youtube.com/DrBrianKeating?sub_confirmation=1
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Michael Saylor The Physics of Bitcoin https://youtu.be/CaN_CDKqXOg?sub_confirmation=1
Sir Roger Penrose, Nobel Prize winner: https://www.youtube.com/watch?v=AMuqyAvX7Wo?sub_confirmation=1
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Sara Seager Venus LIfe: https://youtu.be/QPsEDoOTU6k?sub_confirmation=1
Noam Chomsky: https://youtu.be/Iaz6JIxDh6Y?sub_confirmation=1
Sabine Hossenfelder: https://youtu.be/V6dMM2-X6nk
Sarah Scoles: https://youtu.be/apVKobWigMw
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Infinite Loops: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Thomas J Bevan is an author and essayist. He pens The Commonplace newsletter which includes workshops on writing, movie reviews, and essays on life. We talk about:
Follow Thomas on Twitter at https://twitter.com/thomasjb3van and subscribe to his newsletter at https://thomasjbevan.substack.com/
Jocko Unravelling ✓
Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
What is a liberal democracy without a functional free press? The idea almost seems like a contradiction in terms. The mass media has become both more centralized and more politicized, driving us into closed silos of information and sense-making, and leading many Americans to doubt everything they don't hear from a trusted member of their own political tribe. Jocko & Darryl discuss the historical trends that have led to this situation, and whether there's a way out of the mess.
What Got You There with Sean DeLaney: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Robert A. Iger is Executive Chairman of The Walt Disney Company and Chairman of the Board of Directors. He assumed the role of Executive Chairman in February 2020, having served as Chief Executive Officer since 2005. As Executive Chairman, Mr. Iger directs the Company’s creative endeavors, while leading the Board and providing the full benefit of his experience, leadership and guidance.
Over his 15 years leading the Company, Mr. Iger built Disney into one of the world’s largest and most admired media and entertainment companies, while focusing on the three fundamental pillars of his strategic vision: generating the best creative content possible; fostering innovation and utilizing the latest technology; and expanding into new markets around the world.
Mr. Iger has been named TIME’s Businessperson of the Year (2019); one of the “World’s Most Powerful People” by Forbes magazine (2018); one of the “Top Gun CEOs” by Forbes magazine (2009); one of Fortune magazine's “25 Most Powerful People in Business” (2006, 2007); one of the “Best CEOs” by Institutional Investor magazine (2008, 2009, 2010, 2011); MarketWatch CEO of the Year (2006); and “CEO of the Year” by Chief Executive (2014).
His new autobiography is titled The Ride of a Lifetime: Lessons Learned from 15 Years as CEO of the Walt Disney Company, which offers stories and lessons about dealmaking, leadership, and much more.
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About What Got You There Podcast
What Got You There focuses on the journey behind some of the world’s most successful people, uncovering the strategy, tactics, and routines that helped them get there.
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MInd Pump: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
In this episode of Quah (Q & A), Sal, Adam & Justin answer Pump Head questions about how often to switch up exercises for max gains, if unilateral movements are more beneficial than bilateral movement, whether vitamin supplementation is necessary if you eat a balanced diet, and good qualities (or red flags) to look for in a nutritionist.
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Tales from the Crypt: A Bitcoin Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Join Marty and Matt as they sit down with Mike Brock, lead at TBD, to discuss:
What "is" and what "ought" to be
Mike's history at Block
How bitcoin got integrated at Cash App
How TBD came to be
Creating a decentralized system with limited trust in tbDEX
Creating bitcoin on-ramps for people is a massive hurdle right now
Is tbDEX transitional?
much more
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Artificial Intelligence Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
Ray Dalio is an investor, author, and founder of Bridgewater Associates. Please support this podcast by checking out our sponsors: – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – GiveWell: https://www.givewell.org/ and use code LEX to get donation matched up to $1k – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Ray’s Twitter: https://twitter.com/RayDalio Ray’s Instagram: https://www.instagram.com/raydalio Books & resources mentioned: Ray’s books: https://amzn.to/3swN5uw Ray’s free personality test: https://principlesyou.com/
The Martyrmade Podcast ✓
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In this and the next episode, I will go over the evidence that notorious child trafficker Jeffrey Epstein was a foreign intelligence agent. The next episode will be available only on the Martyr Made Substack. The follow-up episode will be a little too spicy for public release, so it will be available in about a week, for paid subscribers only. For access, subscribe to the Martyr Made Substack for just $5 p/month or $50 p/year.
Knowledge Project: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
The Knowledge Project closes 2021 with a look back at some of the best conversations of the year. Featuring interviews from 10 of the most downloaded and acclaimed episodes of 2021, this collection of conversations offers a variety of insights into how to make crucial decisions, how to spark creativity, the best ways to avoid distraction, how to deal with loneliness, what traits to look for in a leader, the value of re-thinking your position, the importance of personal relationships, and much more. Guests on this episode include: business leader Kat Cole, NBA basketball player Chris Bosh, loneliness expert Noreena Hertz, organizational psychologist Adam Grant, NASA astrophysicist Thomas Zurbuchen, video game expert Jane McGonigal, author Nir Eyal, author and entrepreneur Seth Godin, psychologist Angela Duckworth, and business expert Jim Collins. --
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The "What is Money?" Show ✓
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Eric Weinstein joins me for a multi-episode conversation covering mathematics, physics, history, politics, economics, and money.
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GUEST
Eric's twitter: https://twitter.com/EricRWeinstein
Eric's YouTube: https://www.youtube.com/ericweinsteinphd
Eric's Podcast: https://ericweinstein.org/
PODCAST
Podcast Website: https://whatismoneypodcast.com/
Apple Podcast: https://podcasts.apple.com/us/podcast/the-what-is-money-show/id1541404400
Spotify: https://open.spotify.com/show/25LPvm8EewBGyfQQ1abIsE?si=wgVuY16XR0io4NLNo0A11A&nd=1
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Transcript:
OUTLINE
00:00:00 “What is Money?” Intro
00:00:08 Introduction to Gauge Theory
00:06:06 Wittgenstein’s Ruler, Invariance, and Co-Variance
00:08:36 General Relativity, Prices, and Inflation
00:10:58 Gauge Theory Says There is No “Universal Level”
00:13:27 Marginal Revolution Using the Wrong Differential Calculus?
00:16:48 Utility Theory: Ordinal vs. Cardinal
00:19:37 The St. Petersburg Paradox
00:23:06 Cardinal Utility Exhibits the Structure of a Principal Bundle
00:24:41 NYDIG
00:25:48 Economics as the Geometry of Markets
00:28:54 Competition is Critical for Scientific Progression
00:32:51 How Framing Changes What We See
00:37:26 Exploring Gold as a Gauge Theory
00:41:01 Transactional Anonymity as a Consequence of Gauge Theory
00:42:50 Conservation Laws and the Double-Spend Problem
00:44:42 Satoshi as the Originator of “Logical Physics”
00:46:07 The Big Problem of Bitcoin?
SOCIAL
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WRITTEN WORK
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