JNIS podcast: Recent Episodes

BMJ Group

The Journal of NeuroInterventional Surgery (JNIS) is a leading peer review journal for scientific research and literature pertaining to the field of neurointerventional surgery. The journal launch follows growing professional interest in neurointerventional techniques for the treatment of a range of neurological and vascular problems including stroke, aneurysms, brain tumors, and spinal compression.The journal is owned by SNIS and is also the official journal of the Interventional Chapter of the Australian and New Zealand Society of Neuroradiology (ANZSNR), The Hong Kong Neurological Society (HKNS) and the Neuroradiological Society of Taiwan. * The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

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Evaluating device performance, safety, and procedural efficacy remains essential as mechanical thrombectomy technology for large vessel occlusion (LVO) rapidly evolves. In this episode, JNIS Editor, Dr. Michael Chen, talks with Dr. Marc Ribo, an interventional neurologist at Vall d'Hebron University Hospital in Barcelona, Spain. They discuss his systematic review paper, "Super large bore catheters in the treatment of stroke: systematic review" (https://jnis.bmj.com/content/early/2026/03/27/jnis-2026-025001).
They discuss published data on super large bore catheters (SLACs; inner diameter ≥0.080 inch), highlighting key metrics including first-pass effect, overall recanalization rates, and navigability through tortuous intracranial vasculature.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Optimising mechanical thrombectomy speed and efficiency remains a primary focus in acute ischemic stroke management. In this episode, JNIS Editor, Dr. Michael Chen, talks with Dr. Keiko Fukuda, a neurointerventional fellow at UCLA and practising neurointerventionalist in Monterey, California, and Dr. Victor Szeder, Professor of Radiology, Neurology, and Neurosurgery and Director of the Neurointerventional Fellowship at UCLA.

They talk about their multi-centre paper, "Faster reperfusion with combined delivery catheter systems and aspiration first stroke thrombectomy: a multicenter analysis" (https://jnis.bmj.com/content/early/2026/06/19/jnis-2025-024700). The authors discuss data comparing combined delivery catheter systems against standard aspiration setups, highlighting significantly faster times from groin puncture to clot contact and an impressive 67% first-pass effect. They also share key clinical insights on overcoming severe arterial tortuosity.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Evaluating the 90-day safety and technical feasibility of a percutaneous transvenous approach represents a critical milestone for routing cerebrospinal fluid (CSF) – the clear liquid that cushions the brain and spine – directly into the venous system.

In this episode, JNIS Editor, Dr. Michael Chen, talks with corresponding author Professor Adel Malek (Tufts Medical Center, Boston) (1) to discuss his high-impact paper, "Safety of endovascular shunting for normal pressure hydrocephalus from a prospective, multicenter, single-arm study”.

They discuss the results of this 66-patient, prospective trial, exploring how the novel eShunt system accesses the cerebellopontine angle cistern to drain CSF and relieve pressure.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Neurosurgeon Adel Malek, MD, PhD. Chief of the Cerebrovascular and Endovascular Division in the Department of Neurosurgery, Tufts Medical Center; Professor of Neurosurgery, Tufts University School of Medicine, Boston, USA.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

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Achieving near-complete reperfusion in medium vessel occlusions (MeVO) is linked to smaller final infarct volumes. However, this did not translate into a statistically significant shift in 90-day functional independence.

In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, and Professor Johanna Ospel (1) discuss the post-hoc analysis of the ESCAPE-MeVO trial, titled "Reperfusion grade and clinical outcome following medium vessel occlusion thrombectomy in the Endovascular Treatment to Improve Outcomes for Medium Vessel Occlusion trial".

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Clinical Associate Professor at the University of Calgary and Senior Lecturer at the University of Basel.

The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

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Headache affects up to 90% of patients following aneurysmal subarachnoid hemorrhage (aSAH), often requiring high-dose opioids that can complicate neurological monitoring.

In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, is joined by Professor Peter Kan¹ to discuss a prospective pilot study investigating a novel dural therapy: the infusion of lidocaine (with or without dexamethasone) via the middle meningeal artery (MMA) during aneurysm embolisation.

They explore the safety of this targeted approach, its impact on Visual Analog Scale (VAS) pain scores, and its potential as an opioid-sparing strategy in the neuro-ICU.

Link to the discussed paper: "Middle meningeal artery infusion for headaches after aneurysmal subarachnoid hemorrhage: a pilot study".

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Texas, USA

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Can aqueductal stenosis be treated through a minimally invasive endovascular approach without transgressing brain parenchyma?

In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, speaks with neuro-interventional radiologist Dr. Michal Obrzut¹ about a neurointerventional approach to the management of obstructive hydrocephalus secondary to aqueductal stenosis.

The author describes the underlying concept, technical feasibility in cadaveric models, and potential implications for minimally invasive neurosurgical practice.

Link to the discussed paper: "A novel neurointerventional subarachnoid aqueductoplasty technique for the treatment of aqueductal stenosis: a cadaveric feasibility study"

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

(1) Neurosurgery, Cleveland Clinic Florida, Weston, Florida, USA

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Medical professionals can oftentimes fall under the category of "second victims", as they experience burnout and moral injury from the impacts of their work. Over the course of a neurointerventionalist's medical career, serious complications in procedures are sadly inevitable. These can be difficult to process, and there are not always the systems in place to provide the support needed, either inside or outside of the hospital. A new survey has been carried out to assess the severity and prevalence of negative psychological effects on physicians who have experienced these complications. Dr. Ansaar Rai¹ joins JNIS Editor-in-Chief Dr. Michael Chen to discuss the original research piece, "Unseen wounds: a multinational investigation of neurointerventionalists on the psychological toll of complications".

(1) Interventional Neuroradiology, West Virginia University Rockefeller Neuroscience Institute, Morgantown, West Virginia, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Dr Donald Heck (1) and Dr Peter Kan (2) join JNIS Editor-in-Chief Dr. Michael Chen to discuss the commentary “Middle meningeal artery embolization in the routine care of chronic subdural hematoma?” by D.V. Heck et al.

They highlight key debates around efficacy, safety, and workflow integration as embolization moves closer to becoming a routine therapeutic option.

(1) Triad Radiology Associates, Novant Health Forsyth Medical Center, Winston Salem, North Carolina, USA
(2) Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Pulsatile tinnitus — the perception of a rhythmic sound in sync with the heartbeat — can be a key indicator of underlying vascular or structural pathology. In this episode, JNIS new Editor-in-Chief Dr. Michael Chen speaks with Dr. Madhavi Duvvuri and Dr. Matthew Robert Amans, authors of Non-invasive imaging modalities for diagnosing pulsatile tinnitus: a comprehensive review and recommended imaging algorithm. They are both from the University of California San Francisco, USA.
They discuss the current evidence base, highlight the strengths and limitations of non-invasive imaging techniques such as MRI, MRA, CT, and CTA, and outline a practical algorithm for streamlining diagnosis.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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In the SCENT trial, researchers investigated the effects of the Surpass flow diverter system for treating wide-necked aneurysms. Five-year results of this trial have recently been published in JNIS, presenting the safety and effectiveness outcomes of treatment with the Surpass Streamline flow diverter system. The study analyses the rates of aneurysm occlusion and adverse events.

Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Philip Meyers¹, author of the paper: Five-year results of the SCENT trial with Surpass flow diverters to treat large or giant wide-neck aneurysms

  1. Radiology and Neurological Surgery, Columbia University, New York, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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High risk factors for stroke such as smoking and blood pressure are not equally represented throughout the patient population. These are just two of the socioeconomic influences on cerebrovascular disease. One way to view this association is through the lens of the Area Deprivation Index (ADI), a measure of neighbourhood-level deprivation, and this was the approach of the study discussed in this episode. The study evaluated the association between the ADI and the treatment of ruptured intracranial aneurysms compared with unruptured intracranial aneurysms across multiple centres. Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Alexandra Paul¹, author of the paper: Multicenter study of association between socioeconomic status and treatment of ruptured cerebral aneurysms compared to unruptured cerebral aneurysms: insights from 4,517 patients using the area deprivation index

  1. Department of Neurosurgery, Albany Medical Center, Albany, New York, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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The "River" stent is a novel stent designed specifically to account for the anatomical and procedural requirements of venous sinus stenosis. A multicentre study of the device's safety and efficacy is underway, comprising 39 subjects across 5 US centres. The 1-year results have been recently published in JNIS. Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Athos Patsalides¹, author of the paper: The River study: the first prospective multicenter trial of a novel venous sinus stent for the treatment of idiopathic intracranial hypertension

  1. Department of Neurological Surgery, North Shore University Hospital, Manhasset, New York, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Observations from practice and data analysis have shown that the duration of mechanical thrombectomy procedures are a strong predictor of outcome even with successful procedures. A large multicenter study was conducted which gives insight into choices between catheter types, and strategic decisions to be made during prolonged procedures.

Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Ali Alawieh¹ and Dr. Alejandro Spiotta², two authors of the paper:

Prolonged intracranial catheter dwell time exacerbates penumbral stress and worsens stroke thrombectomy outcomes

  1. Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA

  2. Med Univ S Carolina, Charleston, South Carolina, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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The use of assistive devices when treating unruptured aneurysms is widespread in neurointerventional practice. But there is no standard for how long patients should receive dual anti-platelet therapy after the procedure, to protect them from thrombotic complications. Durations can range from one month to one year. This episode looks at a review of patient data across 12 locations to understand the effect of therapy duration on risk of complications.

Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Andrew Ringer¹, first author of the paper:
Impact of duration of dual anti-platelet therapy on risk of complications after stent-assisted coiling of unruptured aneurysms

  1. Mayfield Clinic, Cincinnati, Ohio, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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There has been a large increase in the number of non-invasive neurovascular studies performed in the last decade, particularly CT angiograms and MR angiograms. What has this meant for catheter-based angiography? This episode looks at an analysis done on a large claims database in the USA, to observe trends in imaging modalities, as well as the distinctions in use by neurosurgeons and radiologists.

Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Francis Jareczek¹ and Dr. D. Andrew Wilkinson¹, two of the authors of the paper:
National trends in catheter angiography and cerebrovascular imaging in a group of privately insured patients in the US.

  1. Neurosurgery, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Although many U.S. neurointerventionalists report at least one stressful malpractice claim over their career, the majority conclude without any court proceedings or direct repercussions in their practice. In this podcast, we look at the prevalence and causes of malpractice claims and complaints filed with state medical boards against neurointerventionalists, and some of the risk factors in an increasingly busier field.

Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr Kyle M. Fargen (Wake Forest University, Winston-Salem); and Dr Joshua A. Hirsch (Massachusetts General Hospital, Boston), both members of the editorial board of the journal and the authors of the paper:
Medical malpractice claims and state medical board complaints among United States neurointerventionalists.

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

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Single-stent assisted coiling techniques such as ‘L-stenting’ are an alternative to intrasaccular devices for wide-neck bifurcation aneurysms. In this episode, Aliya Siddiqui¹ and Dr. Reade De Leacy² join JNIS editor-in-chief Dr. Felipe Albuquerque to discuss the background and findings of their recent study, regarding the efficacy and safety of the 'L-stenting' technique.

Read the paper: A core-lab adjudicated analysis of single-stent assisted coiling of wide-neck bifurcation aneurysms

  1. Medical College of Wisconsin, Milwaukee, USA

  2. Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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Patients with good motor function outcomes after aneurysmal subarachnoid hemorrhage treatment may still be left with neuropsychiatric effects. They can suffer from such difficult conditions as cognitive dysfunction, depression and sexual dysfunction. Not all of these patients will volunteer their symptoms unprompted on follow-up. This outcome type has had limited study, and became an interest of today's guest, Dr. Jose Danilo Bengzon Diestro (1). JNIS editor-in-chief Dr. Felipe Albuquerque speaks with him on this subject, based on the recently published paper, "Long-term neuropsychiatric complications of aneurysmal subarachnoid hemorrhage: a narrative review".

(1) Department of Medicine, University of Toronto, Toronto, Canada

Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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Alis Dicpinigaitis (1) and Dr. Fawaz Al-Mufti (2) join JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Mapping geographic disparities in treatment and clinical outcomes of high-grade aneurysmal subarachnoid hemorrhage in the United States". They explain the findings of their study, covering the predictive impact of factors including age, insurance status, race, and hospital ownership.

Read the paper: https://jnis.bmj.com/content/early/2024/02/19/jnis-2023-021330

(1) New York Presbyterian - Weill Cornell Medical Center, New York, New York, USA

(2) Department of Neurosurgery, Westchester Medical Center at New York Medical College, Valhalla, New York, USA

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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Dr. Michael Veldeman (1) joins JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Intra-arterial nimodipine for the treatment of refractory delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage". Dr. Veldeman explains the methods of the study, the growing significance of computerised tomography perfusion imaging in diagnosis of unconscious patients, the use of induced hypertension, and interventional complications that arose when treating subarachnoid hemorrhage patients.

Read the paper: https://jnis.bmj.com/content/early/2023/12/16/jnis-2023-021151

(1) Department of Neurosurgery, RWTH Aachen University Hospital Aachen, Aachen, Germany

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from New York by Prof. David Fiorella (1) to discuss the paper, "Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT)". Prof. Fiorella explains the results of this extensive study across 27 locations, with the WEB device proving to be a durably effective and safe endovascular treatment option for wide-necked bifurcation aneurysms.

Read the paper: https://jnis.bmj.com/content/15/12/1175

(1) Department of Neurosurgery, State University of New York at Stony Brook, Stony Brook, New York, USA

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from Calgary by Dr. Johanna Ospel (1) to discuss "Recent developments in pre-hospital and in-hospital triage for endovascular stroke treatment", a paper detailing the many aspects of resource allocation when treating stroke patients.

Read the paper: https://jnis.bmj.com/content/early/2022/10/14/jnis-2021-018547

(1) Departments of Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was produced and edited by Brian O'Toole.

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Michael Levitt (1) and Dr. Colin Derdeyn (2), authors of a pair of editorials discussing the practice of dural venous sinus stenting for patients with idiopathic intracranial hypertension.

Point: Dural venous sinus stenting should be considered a first-line treatment option for select patients with idiopathic intracranial hypertension https://jnis.bmj.com/content/early/2023/06/20/jnis-2023-020597

Counterpoint: stenting for idiopathic intracranial hypertension should be trialed
https://jnis.bmj.com/content/early/2023/06/20/jnis-2023-020404

These articles are free-to-access for a month following the publication of this podcast.

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was edited by Brian O'Toole.

(1) Neurological Surgery, University of Washington School of Medicine, Seattle, Washington, USA
(2) Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Marco Colasurdo (1) and Prof. Dheeraj Gandhi (2), authors of the original research article, "Predictors for large vessel recanalization before stroke thrombectomy: the HALT score" - https://jnis.bmj.com/content/early/2023/04/25/jnis-2023-020220

This paper is free-to-access for a month following the publication of this podcast.

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Thank you for listening! This episode was edited by Brian O'Toole.

(1) Interventional Neuroradiology, Dept. of Diagnostic Radiology, Uni. of Maryland Medical Center, Baltimore, Maryland, USA
(2) Dept. of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Marco Colasurdo (1) and Prof. Dheeraj Gandhi (2), authors of the original research article, "Predictors for large vessel recanalization before stroke thrombectomy: the HALT score" - https://jnis.bmj.com/content/early/2023/04/25/jnis-2023-020220This paper is free-to-access for a month following the publication of this podcast. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) Interventional Neuroradiology, Dept. of Diagnostic Radiology, Uni. of Maryland Medical Center, Baltimore, Maryland, USA (2) Dept. of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Mariam Kyarunts(1) and Charlotte Michaelcheck(2), contributing authors to the recently published article "Gender disparities in industry compensation and research payments among neurointerventional surgeons in the USA" - https://jnis.bmj.com/content/early/2023/01/23/jnis-2022-019921This paper is free-to-access for a month following the publication of this podcast. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767Thank you for listening!This episode was edited by Brian O'Toole.(1)Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA(2)Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Kyle Fargen(1) about the recently published study "Mechanical thrombectomy decision making and prognostication: Stroke treatment Assessments prior to Thrombectomy In Neurointervention (SATIN) study" - https://jnis.bmj.com/content/early/2023/01/05/jnis-2022-019741.longPlease subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767Thank you for listening!This episode was edited by Brian O'Toole.(1) Neurological Surgery and Radiology, Wake Forest University, Winston-Salem, North Carolina, USA

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Amanda Baker(1) and Dr. Sandra Narayanan(2) about their recently published standard "Society of NeuroInterventional Surgery: position statement on pregnancy and parental leave for physicians practicing neurointerventional surgery" - https://jnis.bmj.com/content/15/1/5.Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767Thank you for listening!This episode was edited by Brian O'Toole.(1) Radiology and Biomedical Imaging, UCSF, San Francisco(2) Neurointerventional Program and Comprehensive Stroke Program, Pacific Neuroscience Institute, Santa Monica

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Krishna C. Joshi(1) and Dr. Michael Chen(2) about their paper "Endovascular thrombectomy for acute ischemic stroke in patients with cancer: a propensity-matched analysis" - https://jnis.bmj.com/content/14/12/1161.Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767Thank you for listening!This episode was edited by Brian O'Toole.(1) Neurological Surgery, Rush University Medical Center, Chicago(2) Neurological Surgery, Rush University Medical Center, Chicago

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In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Matthew Amans(1) and Daniel Cummins(2) about their paper "Cerebrovascular pulsatile tinnitus: causes, treatments, and outcomes in 164 patients with neuroangiographic correlation" - https://jnis.bmj.com/content/early/2022/09/08/jnis-2022-019259.

Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening!

This episode was edited by Brian O'Toole. (1) School of Medicine, University of California, San Francisco, USA (2) Radiology and Biomedical Imaging, University of California, San Francisco, USA

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The 2013 ARUBA trial concluded that medical management alone is superior to medical management with interventional therapy for patients with unruptured brain arteriovenous malformations. A study was conducted to analyze AVM treatment and epidemiologic response to the ARUBA trial. Following ARUBA, there has been a stark decrease in interventions for uAVMs. Nationwide rAVM discharge incidence is inversely correlated with uAVM intervention rate. Less uAVM interventions may lead to a substantial increase in AVM rupture incidence. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Evan Luther(1) and Dr. Robert Starke(2) about their paper "Unruptured arteriovenous malformation intervention rate is inversely correlated with ruptured AVM discharge incidence" - https://jnis.bmj.com/content/12/suppl_1/a163. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced by Leticia Amorim and edited by Brian O'Toole. (1) Neurological Surgery, University of Miami, Miami, Florida, USA (2) Department of Neurosurgery & Radiology, Miller School of Medicine, University of Miami, Miami, Florida, USA

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Survival for glioblastoma remains very poor despite decades of research, with a 5-year survival of only 5%. Technological improvements that have revolutionized treatment of ischemic stroke and brain aneurysms have great potential in providing more precise and selective delivery of cancer therapeutic agents to brain tumors. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Stephen Chen (1)and Dr. Peter Kan (2) about their paper "Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of malignant brain tumors". The paper describes a technique using perfusion guidance to enhance the precision of endovascular super-selective intra-arterial (ESIA) infusions of mesenchymal stem cells loaded with Delta-24 in the treatment of glioblastoma. This technique enhances targeted super-selective delivery of therapeutic agents for brain tumors. Paper available online (https://jnis.bmj.com/content/14/6/533) and in June print issue of JNIS. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced by Leticia Amorim and edited by Brian O'Toole. (1) Interventional Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2) Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

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The Woven EndoBridge (WEB) device has FDA approval for treatment of wide-necked intracranial bifurcation aneurysms. It has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Nimer Adeeb (1)and Dr. Adam Dmytriw (2) on their paper "Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device". Paper available online: https://jnis.bmj.com/content/early/2022/04/27/neurintsurg-2022-018694 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center (2)Neuroendovascular Program, Massachusetts General Hospital, Harvard University

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Sex disparities in acute ischemic stroke outcomes are well reported with IV thrombolysis. Despite several studies, there is still a lack of consensus on whether endovascular thrombectomy (EVT) outcomes differ between men and women. In this podcast, we discuss the Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) study, in which women had similar discharge outcomes as men following EVT, in a propensity-matched cohort, but the improvement from discharge to 90 days was significantly worse in women, suggesting the influence of post-discharge factors. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Johanna Fifi (Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York) and Amrou Sarraj (Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio). Paper available online: https://jnis.bmj.com/content/early/2022/02/28/neurintsurg-2021-018348. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767. Thank you for listening!

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In the latest podcast, we discuss the joint expedited recommendations from the European Stroke Organisation (ESO) and the European Society for Minimally Invasive Neurological Therapy (ESMINT) on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Guillaume Turc, Department of Neurology, GHU Paris Psychiatrie et Neurosciences, Université de Paris, and co-chair of the module working group. Paper available here: https://jnis.bmj.com/content/14/3/209. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767. Thank you for listening!

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Venous sinus stenting (VSS) is a safe, effective, and increasingly popular treatment option for selected patients with idiopathic intracranial hypertension (IIH). Serious complications associated with VSS are rarely reported. In this podcast, JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Dr. Kyle Fargen, from the Department of Neurosurgery, Wake Forest University, Winston-Salem, North Carolina, about a case series in which serious complications after VSS were identified retrospectively from multicenter databases. The cases are reviewed and learning points regarding complication avoidance and management are presented in his paper (https://jnis.bmj.com/content/early/2021/04/27/neurintsurg-2021-017361).

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In this podcast, we discuss the COMPASS: a trial of aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion, comparing patients with and without prior intravenous (IV) alteplase administration. JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Maxim Mokin, from the Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, USA, about the post hoc analysis. which concludes that prior administration of IV alteplase may adversely affect the efficacy of aspiration, whilst it does not seem to influence the stent retriever first approach to MT in patients with anterior circulation ELVO. Read the related paper on the JNIS website: https://jnis.bmj.com/content/early/2021/10/13/neurintsurg-2021-017943

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Flow diversion of intracranial aneurysms with the Pipeline Embolization Device (PED) is commonly performed, but the value of long-term angiographic follow-up has not been rigorously evaluated. The study discussed in this podcast examines the prevalence of actionable findings of aneurysm recurrence and development of in-stent stenosis in a cohort of patients that underwent long-term angiographic follow-up at multiple time points. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Dr Akash P. Kansagra, from the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, USA. Related paper: https://jnis.bmj.com/content/early/2021/07/01/neurintsurg-2021-017745

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Retinoblastoma is the most common primary intraocular malignancy in children. In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Pascal Jabbour discuss a study from July’s issue, concluding that local factors relating to the chemotherapy and selective microcatheterization of the ophthalmic artery are essential factors in the development of ophthalmic artery thrombosis, as seen by the association of ophthalmic artery thrombosis with the frequency of intra-arterial chemotherapy. Dr Jabbour, Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, USA, is the corresponding author of 'Incidence and predictors of ophthalmic artery occlusion in intra-arterial chemotherapy for retinoblastoma' - https://jnis.bmj.com/content/13/7/652

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In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Adnan Siddiqui discuss a case series that describes complete flow control using concurrent transient rapid ventricular pacing with afferent arterial balloon flow arrest technique as “safe and feasible” for transvenous embolization of select cerebral arteriovenous malformations (AVM). Dr Siddiqui (Department of Neurosurgery, University at Buffalo, NY, USA) is the lead author of “Complete flow control using transient concurrent rapid ventricular pacing or intravenous adenosine and afferent arterial balloon occlusion during transvenous embolization of cerebral arteriovenous malformations: case series”, published in the April 2021 issue of JNIS. Link to the paper: https://jnis.bmj.com/content/13/4/324

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JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Sami Al Kasab and Alejandro Spiotta, both from the Medical University of South Carolina, Charleston, USA. They discuss the Stroke Thrombectomy and Aneurysm Registry data showing an “alarming downtrend in mechanical thrombectomy rates in African American patients during the COVID-19 pandemic”. Read the related article online (https://jnis.bmj.com/content/early/2021/01/06/neurintsurg-2020-016946) and in the March issue of JNIS. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

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Operating rooms contribute between 20% to 70% of hospital waste. Neurointerventional procedures, in particular, generate a substantial amount of that waste: an average of 8 kg per case, recently aggravated by the COVID-19 pandemic. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Pey Ling Shum, Monash Health, Clayton, Victoria, Australia, about her recent paper “Environmental sustainability in neurointerventional procedures: a waste audit” - https://jnis.bmj.com/content/12/11/1053 Please also read the related commentary "Greening the neurointerventional suite" - https://jnis.bmj.com/content/12/11/1037 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

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Sexism is common place in one of the most male-dominated subspecialties in medicine. Despite this, the prevalence of women physicians in neurointervention is steadily rising. In this podcast, JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews neurointerventionalists Stephanie H Chen - Department of Neurological Surgery, University of Miami School of Medicine - and Marie-Christine Brunet - Department of Neurological Surgery (NEUR) at McGill University - about the challenges of being a female physician in this field. They are the authors of the first study examining the amount of maternal and fetal radiation exposure during a pregnant neurointerventional fellow’s training. Spoiler alert: the findings suggest that, when optimal radiation safety practices are implemented, the fetal dose of a pregnant neurointerventionalist is negligible. Read the paper for free for a month on the JNIS website: https://jnis.bmj.com/content/12/10/1014 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

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The recommendations resulting from the report of the SNIS Standards and Guidelines Committee on transarterial access are discussed in this podcast. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Robert Starke (University of Miami MILLER School of Medicine, Miami Beach, Florida, and Westchester Medical Center, Valhalla, New York) and Justin Fraser (University of Kentucky, Lexington), who recently published the paper “Transarterial and transvenous access for neurointerventional surgery: report of the SNIS Standards and Guidelines Committee” on behalf of the Society of NeuroInterventional Surgery. Read the paper on the JNIS website: https://jnis.bmj.com/content/12/8/733

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JNIS Editor-In-Chief Felipe C. Albuquerque discusses idiopathic intracranial hypertension (IIH) and a new patient classification paradigm with Kyle Fargen (Neurological Surgery, Wake Forest University, Winston-Salem, USA) and Michael Levitt (Neurological Surgery, University of Washington, Seattle, USA). Both authors recently wrote about the intersection between IIH and venous sinus stenosis, an increasingly hot topic within the neurointerventional community. In the podcast, the participants discuss this novel classification, venous sinus stenting, and issues pertaining to this diverse patient population. Read the paper and the commentary on the JNIS website: Idiopathic intracranial hypertension is not idiopathic: proposal for a new nomenclature and patient classification https://jnis.bmj.com/content/12/2/110 Commentary: Another version of the truth https://jnis.bmj.com/content/12/4/335

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In a densely populated setting, for patients with stroke who are endovascular therapy candidates and closest to a primary stroke center from the field, triage to a slightly more distant comprehensive stroke center is associated with faster time to endovascular therapy, no delay to alteplase, and less disability at 90 days. Felipe de Albuquerque talks to Mahesh Jayaraman and Ryan McTaggart (Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island, USA) about their paper “Field triage for endovascular stroke therapy: a population-based comparison”, which is part of the March issue of JNIS and can be read for free on the journal's website: https://jnis.bmj.com/content/12/3/233.

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In this podcast, Felipe de Albuquerque talks to Istvan Szikora, Neurointerventions, National Institute of Clinical Neurosciences, Budapest, Hungary, about the official document of Standards for European training requirements in interventional neuroradiology guidelines by the Division of Neuroradiology/Section of Radiology European Union of Medical Specialists (UEMS), in cooperation with the Division of Interventional Radiology/UEMS, the European Society of Neuroradiology (ESNR), and the European Society of Minimally Invasive Neurological Therapy (ESMINT). Read the paper on the JNIS website: https://jnis.bmj.com/content/early/2019/11/15/neurintsurg-2019-015537 .

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In this podcast, Editor-in-Chief of JNIS Felipe C. Albuquerque talks to Justin F. Fraser, Neurological Surgery, University of Kentucky, about the current endovascular strategies for posterior circulation large vessel occlusion stroke: the report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee. Read the paper for free on the JNIS website: https://jnis.bmj.com/content/11/10/1055.

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In this podcast, Editor-in-Chief of JNIS Felipe C. Albuquerque talks to Eric Peterson (University of Miami MILLER School of Medicine, Miami, Florida, USA) about the novel technique of distal transradial access in the diagnostic cerebral angiography. The paper is the Editor’s Choice article of the July issue of JNIS. Read it online: https://jnis.bmj.com/content/11/7/710.

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Although the impact of Brexit on research is still unknown, BMJ’s CEO Peter Ashman is confident medical publishing “will be OK”. In this special podcast, Publishing Director of BMJ, Allison Lang, assures the American audience of JNIS that the turmoil in the UK over leaving the European Union should have no impact on the specialty journals of the BMJ Publishing Group.

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In the January 2019 podcast, Felipe C. Albuquerque talks to Reade De Leacy about the BRANCH (wide-neck bifurcation aneurysms of the middle cerebral artery and basilar apex treated by endovascular techniques)- a multicentre, retrospective study comparing core lab evaluation of angiographic outcomes with self-reported outcomes. Read the JNIS Editor's Choice paper here: https://jnis.bmj.com/content/11/1/31.

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There are two editor's choice papers of the November issue of JNIS discussed in this podcast. Editor-in-Chief of JNIS, Felipe de Albuquerque, talks to Ashutosh Jadhav and Shashvat Desai, both from the Department of Neurology, University of Pittsburgh Medical Center, Pennsylvania, USA. They are co-authors of the papers: Thrombectomy 6-24 hours after stroke in trial ineligible patients (https://jnis.bmj.com/content/10/11/1033) Thrombectomy 24 hours after stroke: beyond DAWN (https://jnis.bmj.com/content/10/11/1039).

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The recommendations of the report of the Society of Neurointerventional Surgery (SNIS) Standards and Guidelines Committee for endovascular strategies for cerebral venous thrombosis are discussed in this podcast. Editor-in-Chief of JNIS, Felipe de Albuquerque, talks to Justin Fraser (Department of Neurological Surgery, University of Kentucky, Lexington, USA) on behalf of the Society of NeuroInterventional Surgery. Read the paper on the JNIS website: https://jnis.bmj.com/content/10/8/803

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M2 occlusions can present with serious neurological deficits, resulting in large infarcts and significant morbidity and mortality. The paper discussed in this podcast concludes that patients with M2 occlusions and higher baseline deficits (NIHSS score ≥9) may benefit from endovascular therapy, thus potentially expanding the category of acute ischemic strokes amenable to intervention. Listen to the conversation between the Editor-in-Chief of JNIS, Felipe de Albuquerque, and Ansaar Rai (Department of Interventional Neuroradiology, West Virginia University Hospital, USA), who is the co-author of “A population-based incidence of M2 strokes indicates potential expansion of large vessel occlusions amenable to endovascular therapy”. Read the Editor’s Choice paper of June 2018 on the JNIS website: jnis.bmj.com/content/10/6/510.

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The use of balloon guide catheters (BGCs) during mechanical thrombectomy for acute ischemic stroke is associated with superior clinical and angiographic outcomes, concludes a systematic review and meta-analysis recently published by JNIS and discussed in this podcast. Waleed Brinjikji (Departments of Radiology and Neurosurgery of the Mayo Clinic, Rochester, Minnesota, USA) tells the Editor-in-Chief of the journal Felipe Albuquerque the details of his paper ‘Impact of balloon guide catheter on technical and clinical outcomes: a systematic review and meta-analysis’. Read the Editor’s Choice of April 2018: http://jnis.bmj.com/content/10/4/335

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A low baseline Alberta Stroke Programme Early CT Score (ASPECTS) is strongly associated with low rates of favorable outcome in patients with acute stroke. The study discussed in this podcast evaluated the efficacy and safety of revascularization therapy in patient with ASPECTS ≤5 in anterior circulation infarct, concluding that revascularization therapy contributed to a favorable clinical outcome at 90 days, especially in patients younger than 70 years. The Editor-in-Chief of JNIS Felipe Albuquerque is joined by Vincent Costalat (Department of Neuroradiology, CHRU Gui de Chauliac, Montpellier, France), who co-authored the paper: "Favorable revascularization therapy in patients with ASPECTS ≤ 5 on DWI in anterior circulation stroke". Read the full details of this article published in the January 2018 issue of JNIS here: http://jnis.bmj.com/content/10/1/5.

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In this podcast, the Editor-in-Chief of JNIS Felipe Albuquerque speaks to Raul Nogueira (Department of Neurology, Emory University School of Medicine/Marcus Stroke & Neuroscience Center, Atlanta, Georgia, USA). He is the co-author of the study "Too good to intervene? Thrombectomy for large vessel occlusion strokes with minimal symptoms: an intention-to-treat analysis". Read the full paper published in the October 2017 issue of the journal also on the JNIS website: http://dx.doi.org/10.1136/neurintsurg-2016-012633. The second article mentioned in this podcast, "Thrombectomy versus medical management for large vessel occlusion strokes with minimal symptoms: an analysis from STOPStroke and GESTOR cohorts", can be found here: http://dx.doi.org/10.1136/neurintsurg-2017-013243.

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Diagnosing with clinical scales or imaging? The transfer decision process of patients with large vessel occlusion (LVO) stroke to receive thrombectomy is discussed in this podcast. The Editor-in-Chief of JNIS Felipe Albuquerque speaks to Michael Chen (Department of Neurological Surgery, Rush University Medical Center, Chicago, USA) about his co-authored study ‘Predictors of false-positive stroke thrombectomy transfers’, published in the September 2017’s issue of the JNIS. Read the full paper on the journal's website: http://jnis.bmj.com/content/9/9/834.

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JNIS Associate Editor Joshua Hirsch is joined by Shazam Hussain (Cerebrovascular Center, Cleveland Clinic, Ohio, USA) and David Fiorella (Department of Neurosurgery, Stony Brook University, New York, USA) to discuss the June 2017's editorial in the Journal of Neurointerventional Surgery.

In this commentary, they analyse the conclusions of the study “Public Health Urgency Created by the Success of Mechanical Thrombectomy Studies in Stroke”, published by Circulation, stating that the opinions of Drs Hopkins and Holmes “lead to unwarranted conclusions that have dangerous implications for patient care”.

The authors of the JNIS editorial comment on three major points of controversy: (1) a disregard for training, expertise, and experience in the management of a disease that may lead to death or disability when treating physicians do not have them; (2) a misunderstanding of the fundamental underpinnings of stroke physiology and anatomy; (3) a false association between a real problem (undeveloped systems of care) and a spurious assumption (ie, that there are not enough physicians trained to perform intracranial MT). We examine these concerns below.

The editorial “In defense of our patients” was written on behalf of the Society of NeuroInterventional Surgery, the Cerebrovascular Section of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, and the Society of Vascular and Interventional Neurology.

Read the full article on the JNIS website: jnis.bmj.com/content/9/6/525.

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The direct aspiration first pass technique (ADAPT) has been introduced as a simple and fast method for achieving good angiographic and clinical outcomes using large bore aspiration catheters for the treatment of acute ischemic stroke (AIS). A study recently published in JNIS by Dr Turk et al. conclude that ADAPT is an effective method to achieve good clinical and angiographic outcomes, and serves as a useful firstline method for revascularization. In this podcast, The Editor-in-Chief of JNIS Felipe Albuquerque and Aquilla Turk discuss the details of this single center's long term experience with ADAPT. The paper “Long term experience using the ADAPT technique for the treatment of acute ischemic stroke” can be found on the JNIS website (http://jnis.bmj.com/content/9/5/437) and on the May 2017's edition of the journal.

Read the other study mentioned in this podcast, "The ‘pit-crew’ model for improving door-to-needle times in endovascular stroke therapy: a Six-Sigma project", here: http://jnis.bmj.com/content/8/5/447.

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The impact of recent guidelines for endovascular management of emergent large vessel occlusion (ELVO) awarding top tier evidence to the same selective criteria in recent trials is discussed in this podcast.

The Editor-in-Chief of JNIS Felipe Albuquerque talks to the two main authors of the study, "Implications of limiting mechanical thrombectomy to patients with emergent large vessel occlusion meeting top tier evidence criteria". Rohini Bhole and Adam Arthur (University of Tennessee Health Sciences Center) explain how guideline adherence impacted treatment numbers and outcomes in a cohort of patients from a comprehensive stroke centre.

Read the full paper: http://jnis.bmj.com/content/9/3/225.

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In this podcast about the healthcare policy, Associate Editor of JNIS and Chair of the SNIS Health Care policy and Economic committee Josh Hirsch is joined by co-authors Andrew Rosenkrantz, from the Department of Radiology, NYU Langone Medical Center, and by Gregory Nicola, from the Hackensack Radiology Group, to discuss MACRA Quality Payment Program episodic care payments, costs of care and implications to neurointerventional specialists.

In times of change in the American Administration, the group reflects on what elements of the MACRA/QPP will remain and which might change or even disappear.

Read the related articles: http://jnis.bmj.com/content/early/2016/12/01/neurintsurg-2016-012885 http://jnis.bmj.com/content/early/2016/11/24/neurintsurg-2016-012845

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In this introductory podcast of Felipe Albuquerque, the new Editor-in-Chief of JNIS talks with Ryan McTaggart, who co-authored the study, "Decreasing procedure times with a standardized approach to emergent large vessel occlusion (ELVO) cases".

The study was run at the single comprehensive stroke center at the Rhode Island Hospital and concluded that a standardized approach to the equipment used and process for ELVO cases at a single institution can dramatically reduce procedure times.

Read the full paper at the JNIS website: http://jnis.bmj.com/content/9/1/2.

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In this farewell podcast of the JNIS Editor-in-Chief, Robert Tarr talks vertebral augmentation practice with Associate Editor Joshua Hirsch and Ronil Chandra.

Dr J A Hirsch, from the Massachusetts General Hospital, Harvard Medical School, USA, and Dr R V Chandra, from the Interventional Neuroradiology Service, Monash University, Melbourne, Australia, are the leading authors of the study "Analysis of vertebral augmentation practice patterns: A 2016 update", published in the December 2016 print edition of JNIS.

Read the full article here: http://jnis.bmj.com/content/8/12/1299.

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In this podcast, Andrew Kofke, from the Departments of Anesthesiology and Critical Care and Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA, reveals the details of his JNIS Editor's Choice paper published in the November 2016 issue.

The study concludes that anesthetic techniques and associated physiology used in endovascular management of acute ischemic stroke (EMAIS) are not homogeneous, making any statements about the effects of generic general anesthesia in stroke ambiguous. In "Anesthetic variation and potential impact of anesthetics used during endovascular management of acute ischemic stroke" the authors also conclude that the type of general anesthesia may affect the outcome after EMAIS.

Read the full details here: http://jnis.bmj.com/content/early/2015/11/27/neurintsurg-2015-011998.full.pdf.

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In this podcast, the Editor-in-Chief of JNIS, Robert Tarr, is joined by Ali Alaraj, the corresponding author of the study, "Increased prevalence and rupture status of feeder vessel aneurysms in posterior fossa arteriovenous malformations".

Dr Alaraj, from the Department of Neurosurgery, Neuropsychiatric Institute University of Illinois, Chicago, USA, explains why are posterior cranial fossa arteriovenous malformations (AVMs) more prone to developing associated aneurysms, specifically feeder vessel aneurysms. Feeder vessel aneurysms are more likely to be the source of hemorrhage in the posterior fossa. As such, they may be the most appropriate targets for initial and prompt control by embolization or surgery due to their elevated threat.

Read the full paper here: http://jnis.bmj.com/content/8/10/1021.full.

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In this podcast, the Editor-in-Chief of JNIS, Robert Tarr, is joined by David Fiorella, the corresponding author of the study, "Final results of the US humanitarian device exemption study of the low-profile visualized intraluminal support (LVIS) device".

Dr Fiorella, from the Department of Neurological Surgery, Stony Brook University Medical Center, New York, concludes that the LVIS device facilitates coil embolization of wide-necked intracranial aneurysms with high rates of technical success. The process also granted an excellent safety profile, and very high rates of complete and near-complete occlusion at follow-up.

Read the full paper here: http://jnis.bmj.com/content/early/2015/09/21/neurintsurg-2015-011937.full

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In this podcast, Dr Robert Tarr interviews Dr Matthew Gounis and Dr Ajit Puri on their latest study, "Grading of Regional Apposition after Flow-Diverter Treatment (GRAFT): a comparative evaluation of VasoCT and intravascular OCT".

GRAFT is a semi-automated image post-processing software, which uses intuitive two-dimensional representations of wall apposition from either high-resolution contrast-enhanced cone-beam CT (VasoCT) or intravascular optical coherence tomography (OCT) images. The technique brings great prospects of reducing stroke-related complications when treating intracranial aneurysms. It delivers quantitative and visually convenient representations of potential flow diverter malapposition and occasional acute thrombus formation.

The paper, published on the August 2016 issue of JNIS, can be read here: http://jnis.bmj.com/content/8/8/847.full.

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In this podcast, Dr Demetrius Lopes tells Robert Tarr, the Editor of JNIS, the details of the study "Arteriovenous malformation embocure score: AVMES".

Demetrius Lopes, a neuroendovascular surgeon at Rush University Medical Center, Chicago, Illinois, USA, is the corresponding author of this study selected as Editor's choice for the July issue of JNIS, which is fully accessible here: http://jnis.bmj.com/content/8/7/685.full

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In this podcast, the Editor of JNIS, Robert Tarr, talks to Christof Karmonik, from the Houston Methodist Research Institute, USA, about the details of the study "Three-dimensional printing of anatomically accurate patient specific intracranial aneurysm models".

The research concluded that the 3D printed aneurysm models were accurate and able to be produced inhouse. Read the full paper here: http://jnis.bmj.com/content/early/2015/04/10/neurintsurg-2015-011686.full

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In this podcast, Dr David Liebeskind, explains the details of the paper "Early arrival at the emergency department is associated with better collaterals, smaller established infarcts and better clinical outcomes with endovascular stroke therapy: SWIFT study".

Dr David Liebeskind, from the Neurovascular Imaging Research Core, UCLA Department of Neurology, Los Angeles, USA, is interviewed by Dr Robert Tarr, Editor-in-Chief of the JNIS.

Read the full article here: http://jnis.bmj.com/content/8/6/553.full

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With multiple RCTs demonstrating clear benefit of mechanical thrombectomy in ELVO, the question of best approach to patients eligible for simultaneous treatment with IV TPA and mechanical thrombectomy has been debated. Dr. Hirsch interviews Drs. Leslie-Mazwi and Weber after their instructive papers on this topic.

Read the full papers: “Does the use of IV tPA in the current era of rapid and predictable recanalization by mechanical embolectomy represent good value?” is available here: http://jnis.bmj.com/content/8/5/443.full.

“Comparison of outcome and interventional complication rate in patients with acute stroke treated with mechanical thrombectomy with and without bridging thrombolysis” is accessible here: http://jnis.bmj.com/content/early/2016/02/22/neurintsurg-2015-012236.full.

“Direct to embolectomy without IV tPA: the stage is set for a randomized controlled trial” is available here: http://jnis.bmj.com/content/early/2016/04/05/neurintsurg-2016-012388.full.

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In this podcast, Dr Thomas Mattingly explains the details of this study conducted in swines and which gives insights into wether endovascular selective hypothermia can provide neuroprotection within time frames relevant to acute ischemic stroke treatment.

Read the full article here: http://jnis.bmj.com/content/8/4.toc .

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In this podcast, Italo Linfante, Miami Cardiac and Vascular Institute and Neuroscience Center, Baptist Hospital, Miami, USA, tells JNIS’ Editor Robert Tarr, the details of his study “Predictors of poor outcome despite recanalization: a multiple regression analysis of the NASA registry”. To access the full article, click here: http://goo.gl/wNEljN .

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In this podcast we find the details of the study "An update to the Raymond-Roy Occlusion Classification of intracranial aneurysms treated with coil embolization". Professor Robert Tarr interviews Justin Mascitelli, the author of the article, which can be read here: http://goo.gl/9IEX8L.

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In this podcast Dr Robert Tarr talks to Dr Michael Chen about his editors choice paper "Critical assessment of the morbidity associated with ruptured cerebral arteriovenous malformations".

They discuss the reasons for undertaking the study, the controversy surrounding the ARUBA trial and the possibility of continuing the research with a larger sample size.

Full paper>> http://jnis.bmj.com/content/early/2015/01/07/neurintsurg-2014-011517.full?sid=2dd0bc6c-36e4-4409-b7bd-c2c173e0dc41

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What understanding do we have of the rupture risk and healing following aneurysm treatment?

Robert Tarr interviews Ram Kardivel, of the Neuroradiology Research Laboratory, Mayo Clinic, USA, on the main conclusions of her study "Gene expression comparison of flow diversion and coiling in an experimental aneurysm model". Read the full article here: goo.gl/WpaqXz

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In this podcast Dr Robert Tarr talks to Dr Matt Gounis and his team Dr Juyu Chueh and Dr Srinivasan Vedantham about their editors choice paper. In this podcast they discuss their methodology and the drawbacks of this kind of study.

Full paper >> http://jnis.bmj.com/content/7/9/676.full

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In this podcast Dr Robert Tarr speaks to Dr Ali Seifi about his recent paper that was selected as editors choice. This podcast covers the differences in mortality and patient outcome between endovascular coiling and surgical clipping and discusses possible chances for a future aneurysm registry.

Full paper >> http://jnis.bmj.com/content/7/10/728.full?sid=16c2199c-8711-4039-aab9-aa10a1496033

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Bias and peer review are of universal importance to all those that produce scholarly work. Fiona Godlee and Rob Tarr, editors in chief of The BMJ and JNIS respectively, share their insights and experience on these highly topical issues with Joshua Hirsch.

Read the related paper: http://jnis.bmj.com/content/early/2015/04/17/neurintsurg-2015-011781.full

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The system of healthcare delivery in the United States is in the midst of a meaningful transition. Traditional fee for service paradigms are moving towards what has been termed value-based approaches. Doctors Joshua HIrsch, Geraldine Mcginty and Greg Nicola examine recent developments and discuss how specialist can participate and help lead that transition.

Listeners to the podcast might enjoy reading the following JNIS articles that are associated with the discussion:

The Bundled Payments for Care Improvement Initiative http://goo.gl/ddQU5r

The Burwell roadmap http://goo.gl/33qM3H

The Bundled Payments for Care Improvement Initiative http://goo.gl/5aBQX7

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On Dec 17th 2014, the NEJM published the results of MR CLEAN; a Dutch study comparing patients treated with intra-arterial thrombolysis to those of a medically managed cohort. The design of this trial was ingenious; focusing attention on patients who appeared to have failed intravenous thrombolysis. The IAT managed group performed quite favorably with respect to this control group.

Three associate editors, Drs. Hirsch, Fiorella and Mocco discuss the impact of MR CLEAN and their personal loss of equipoise in this cohort of patients.

Listeners to this podcast might enjoy the following articles, which have been published in JNIS that are referred to in the podcast.

The Tribulations of Stroke Trials: http://jnis.bmj.com/content/5/3/181.long

In search of the optimized stroke trial design. J Neurointerv Surg. 2014 May;6(4):249-51. doi: 10.1136/neurintsurg-2014-011204.

A meta-analysis of prospective randomized controlled trials evaluating endovascular therapies for acute ischemic stroke. J Neurointerv Surg. 2015 Feb;7(2):84-9. doi: 10.1136/neurintsurg-2014-011543. Epub 2014 Nov 28.

Endovascular therapy for acute ischemic stroke is indicated and evidence based: a position statement. J Neurointerv Surg. 2015 Feb;7(2):79-81. doi: 10.1136/neurintsurg-2014-011591. Epub 2014 Dec 18.

A research roadmap of future endovascular stroke trials. J Neurointerv Surg. 2015 Feb;7(2):82-3. doi: 10.1136/neurintsurg-2014-011592. Epub 2014 Dec 18. No abstract available.

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With advances in device design, patient selection paradigms and other elements of treatment, the neuroendovascular approach to acute ischemic stroke has made great strides forward.

In this podcast, Dr Joshua Hirsch interviews Dr Brijesh Mehta on how the implementation of operational improvements can meaningfully impact patient outcomes.

Dr Mehta is a neuroInterventional surgeon at the Memorial Neuroscience Institute in south Florida, where he directs the Comprehensive Stroke Center and Neurointensive Care Unit.

These articles published in the JNIS might be of interest to people who enjoy this podcast:

Applying the Lean management philosophy to NeuroInterventional radiology http://goo.gl/c0x5Zl

Establishing operational stability—developing human infrastructure http://goo.gl/623WtS

‘Time’ for success http://goo.gl/rgJ0U7

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Pretreatment Alberta Stroke Program Early CT Scores (ASPECTS) is associated with clinical outcomes. The rate of decline between subsequent images, however, may be more predictive of outcomes as it integrates time and physiology.

A paper published in the January issue of JNIS retrospectively looked at patients transferred from six primary stroke centers and treated with intra-arterial therapy (IAT). They found patients with faster rates of ASPECTS decay during inter-facility transfers are associated with worse clinical outcomes.

Rob Tarr discusses the work with co-author Rishi Gupta, Wellstar Neurosurgery, Marietta, USA.

Read the full paper: http://jnis.bmj.com/content/7/1/22.full

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Could morphology and growth predict rupture?

Despite several landmark studies, the natural history of unruptured intracranial aneurysms (UIA) remains uncertain.

Rob Tarr talks to William Mehan, Division of Neuroradiology, Massachusetts General Hospital, about his paper which aimed to identify or confirm factors predictive of rupture of UIA being observed conservatively with serial CT angiography in a North American patient population.

Read the full paper (for free): http://jnis.bmj.com/content/6/10/761.full

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Immune dysregulation influences outcome following acute ischemic stroke (AIS). Admission white blood cell counts are routinely obtained, making the neutrophil–lymphocyte ratio (NLR) a readily available biomarker of the immune response to stroke.

With colleagues Taura Barr, WVU Prevention Research Center, One Medical Center Drive, sought to identify the relationship between NLR and 90 day AIS outcome. Rob Tarr asks her what they found.

Read the full paper: http://goo.gl/nGXmYO

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Symptomatic subacute/chronic large artery intracranial occlusive disease represents a common medical dilemma. A recent JNIS paper reports a multicenter experience of endovascular recanalization of intracranial atherosclerotic occlusions refractory to medical therapy.

Robb Tarr talks to co-author Raul Nogueira, Department of Neurology, Marcus Stroke and Neuroscience Center/Grady Memorial Hospital/Emory University.

Read the full paper: http://jnis.bmj.com/content/6/9/645.full

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Aneurysmal subarachnoid hemorrhage (SAH) is a rare but devastating form of stroke. Endovascular therapy has been criticized for its higher rate of recanalization and retreatment. The safety and predictors of retreatment are unknown.

A recent study in JNIS reports the clinical outcomes, imaging outcomes and predictors for aneurysm retreatment after initial endovascular embolization.

Rob Tarr speaks with co-author Dr Osama Zaidat, Vascular and Interventional Neurology/Department of Neurology, Medical College of Wisconsin/Froedtert Hospital.

Read the full paper: Safety and predictors of aneurysm retreatment for remnant intracranial aneurysm after initial endovascular embolization http://jnis.bmj.com/content/6/7/490.full

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The Patient Protection and Affordable Care Act (ACA) became law on 23 March 2010. As part of the law, two independent boards were established. The Patient-Centered Outcomes Research Institute embodies national aspirations for employing comparative effectiveness research in healthcare decision-making, and the Independent Payment Advisory Board is focused on the need for a group of impartial experts to establish anticipatable growth rates for Medicare.

Approximately 4 years after the bill was passed into law, these independent boards are at very different points in their life cycles.

In this podcast, Josh Hirsch, Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Geraldine McGinty, Department of Radiology, Weill Cornell Medical College, New York, and Richard Duszak, Vice Chair for Health Policy and Practice, Department of Radiology and Imaging Sciences, Emory University School of Medicine, give us a status update.

Read the related article: http://goo.gl/mNRI8g

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Newer flat panel angiographic detector (FD) systems have the capability to generate parenchymal blood volume (PBV) maps. The ability to generate these maps in the angiographic suite has the potential to markedly expedite the triage and treatment of patients with acute ischemic stroke.

David Fiorella, Department of Neurological Surgery, Stony Brook University Medical Center, NY, and colleagues, have compared FP-PBV maps with cerebral blood volume (CBV) maps derived using standard dynamic CT perfusion (CTP) in a population of patients with stroke.

Rob Tarr asks him what they found.

Read the full paper: http://jnis.bmj.com/content/6/6/451.full

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US physicians nearly universally use the CPT coding system. This code set communicates medical, procedural, surgical and diagnostic services and is a critical component of describing the work we do.

Drs. Josh Hirsch, Jackie Bello and Raymond Tu are actively involved in the world of physician reimbursement through their associations with the Relative-Value Update Committee (RUC) and Current Procedural Terminology (CPT) committees.

In this podcast they discuss the role CPT plays in physician reimbursement and its interplay with the RUC and Centers for Medicare & Medicaid Services (CMS).

The JNIS article being discussed is:

Current procedural terminology; a primer http://goo.gl/TIhC8N

Listen to Dr Hirsch's previous podcast on component coding and the RUC: http://goo.gl/KcEbk4

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The development of new revascularization devices has improved recanalization rates and time but not clinical outcomes. In a paper in May's JNIS, Aquilla Turk, Department of Radiology, Medical University of South Carolina, ad colleagues, report their initial results with a new technique utilizing a direct aspiration first pass technique with a large bore aspiration catheter as the primary method for vessel recanalization.

Rob Tarr discusses the findings with Dr Turk and also Marc Chimowitz, Department of Neurosciences, Medical University of South Carolina, who has written an accompanying editorial.

Read the articles:

Initial clinical experience with the ADAPT technique: A direct aspiration first pass technique for stroke thrombectomy http://goo.gl/H1MQqb

Game changer for endovascular treatment of acute ischemic stroke? http://goo.gl/JFkDM0

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Drs. Hirsch, Meyers and Jayaraman discuss the evolving and at times complex role of Evidence Based Medicine (EBM) in contemporary neurointerventional practice. The discussants contrast EBM with Comparative Effectiveness Research and the role it plays in coverage decisions.

The podcast directly links to the following articles:

http://www.ncbi.nlm.nih.gov/pubmed/24578482?dopt=Abstract

General considerations:

http://www.ncbi.nlm.nih.gov/pubmed/22166819

http://jnis.bmj.com/content/4/1/11.long

Why standards:

http://www.ncbi.nlm.nih.gov/pubmed/21994097

http://jnis.bmj.com/content/1/1/5.long

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The difference in the relationship between the size of intracranial aneurysms (IAs) and their risk of rupture in patients with singe IAs versus those with multiple IAs is unclear.

A recent JNIS paper retrospectively analysed the size of ruptured IAs (RIAs) in patients with single and multiple IAs, in order to study this relationship further. JNIS editor Rob Tarr spoke to author Bharathi Jagadeesan, Department of Radiology, University of Minnesota, about the outcome.

Read the paper here: http://goo.gl/EKHMyf

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The efficacy of hypothermia as a neuroprotectant has yet to be demonstrated in acute ischemic stroke.

Researchers at Emory University School of Medicine conducted a phase I pilot study to assess the feasibility and safety of performing intravascular hypothermia after definitive intra-arterial reperfusion therapy (IAT), and in this podcast co-author Rishi Gupta tells Rob Tarr what they found.

Read the full paper:

Endovascular Reperfusion and Cooling in Cerebral Acute Ischemia (ReCCLAIM I) http://goo.gl/yiNQKk

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JNIS editor-in-chief Rob Tarr talks to Mike Froehler, Department of Neurology, University of Iowa Hospital, about his paper which revealed the hyperdense vessel sign on CT in acute ischemic stroke was strongly predictive of successful recanalization using the Merci device.

Read the full paper here: http://goo.gl/D7klFb

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Nearly annually, US healthcare providers face a significant downward revision to their Medicare fee schedule secondary to the application of the sustainable growth rate formula. Recent developments raise the possibility that this unsustainable situation might soon change; for the better.

Drs Josh Hirsch, David Rosman and Raymond Liu review the sustainable growth rate and discuss how it works. In closing out the podcast, they review the circumstances that are potentially leading to an end of this historic challenge.

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JNIS editor Rob Tarr talks to Darren Orbach, Department of Neurointerventional Radiology, Children's Hospital Boston, about his recent editor's choice paper: Angioarchitectural features associated with hemorrhagic presentation in pediatric cerebral arteriovenous malformation.

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Drs Josh Hirsch, Bill Donovan and Zeke Silva are actively involved in the world of physician reimbursement through their volunteer associations with organizations like the ACR, ASNR and the RUC, amongst others. This podcast is suitable for beginners or aficionados as the physician discussions will range from the history of the RUC to nuances of the erosion of component coding.

The authors will use this platform to discuss the following two articles:

The RUC: a primer for neurointerventionalists http://bit.ly/ZGrMSG

Component coding and the neurointerventionalist: a tale with an end http://bit.ly/11yVJ79

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Rob Tarr, JNIS editor, talks to Jennifer Frontera, Neurosurgery, Mount Sinai School of Medicine, about her study showing aneurysm coiling followed by ICH evacuation is a viable alternative to clipping and ICH evacuation, for subarachnoid hemorrhage with intracerebral hematoma.

See also:

Management of subarachnoid hemorrhage with intracerebral hematoma: clipping and clot evacuation versus coil embolization followed by clot evacuation http://bit.ly/XnJABz

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JNIS editor Rob Tarr talks to Kyle Fargen, Department of Neurosurgery, University of Florida, about his pilot study looking at simulator based angiography education, and the potential of the technique.

See also:

Simulator based angiography education in neurosurgery: results of a pilot educational program http://bit.ly/TMPoOC

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JNIS editor Rob Tarr talks to Aquilla Turk (Medical University of South Carolina) about his study into CT perfusion-guided patient selection for endovascular treatment of ischemic stroke, which has shown it is safe and effective.

See also:

CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effective http://bit.ly/Oti4yf

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JNIS editor Rob Tarr talks to Raul Nogueria (Emory University School of Medicine, Atlanta) about the new Trevo device, and the results of of his preclinical study on it.

See also:

The Trevo device: preclinical data of a novel stroke thrombectomy device in two different animal models of arterial thrombo-occlusive disease http://bit.ly/11hulZv

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JNIS editor Rob Tarr talks to Ning Lin (Brigham and Women’s Hospital, Boston) about the paradigm shift in treatment of ruptured, and unruptured, cerebral aneurysms in the USA.

See also:

Treatment of ruptured and unruptured cerebral aneurysms in the USAhttp://bit.ly/11ALqOO

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JNIS editor Rob Tarr talks to Charles Kerber (University of California San Diego Medical Center) about Neucrylate, a new treatment for berry aneurysms.

Dr Kerber describes how his company developed the liquid embolic device, the results they’ve had using it, and future plans to get it into practice.

See also:

1-Hexyl n-cyanoacrylate compound (Neucrylate™ AN), a new berry aneurysm treatment. II. Rabbit implant studies: technique and histology http://bit.ly/17g34e7

1-Hexyl n-cyanoacrylate compound (Neucrylate™ AN), a new berry aneurysm treatment. I. Theoretical basis and laboratory evaluation http://bit.ly/YKON3y

1-Hexyl n-cyanoacrylate compound (Neucrylate™ AN), a new treatment for berry aneurysm. III: Initial clinical results http://bit.ly/10wAIx4

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In this podcast, Robert Tarr, JNIS editor, talks to Marc Lazzaro, Medical College of Wisconsin, about his paper The impact of diabetes on the extent of pial collaterals in acute ischemic stroke patients - September’s Editor’s Choice.

See also:

Ischemic stroke - The impact of diabetes on the extent of pial collaterals in acute ischemic stroke patients http://bit.ly/12FlgNg

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In the monthly JNIS podcast, we will hear from some of the researchers who have published in the journal about their work.

In this inaugural podcast, Robert Tarr, JNIS editor, talks to Raymond Turner, Medical University of South Carolina, about his paper Novel Non-Occlusive Temporary Endoluminal Neck Protection Device to Assist in the Treatment of Aneurysms in a Canine Model - September’s Editor’s Choice.

See also:

New devices - Novel non-occlusive temporary endoluminal neck protection device to assist in the treatment of aneurysms in a canine model http://bit.ly/YKNH7Z