QuadShot News Podcast: Recent Episodes

Laura, Caleb, and Sam

With increasing information overload and packed work schedules, staying up-to-date on the newest oncologic advances is harder than ever. But take heart! The QuadShot is freshly brewed four mornings each week so you can quickly down and digest the day's most pertinent cancer news.

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Check out this week's QuadCast where we highlight the strength of weekly cisplatin, if proton therapy is ok in breast cancer, the benefit of ctDNA clearance in breast cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this episode of the QuadCast where we highlight zero margin brain SRS, the benefit of chemoradiation in pancreatic cancer, the ability to reduce radiation dose in myxoid liposarcoma, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight testosterone replacement in favorable prostate cancer, SABR for breast cancer without surgery, smaller GBM margins, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's episode as we highlight immunotherapy in rectal cancer, single vocal cord radiation, and how to use a TrueBeam to deliver FLASH RT.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out the website and subscribe to the newsletter! www.quadshotnews.com Founders & Lead Authors: Laura Dover & Caleb Dulaney Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the benefits of statins on aortic functioning in patients receiving anthracycline chemotherapy, the potential of nimotuzumab in cervical cancer, and the neurocognitive recovery seen after SRS compared to whole brain RT.

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Check out this week’s QuadCast as we highlight the role of elective nodal treatment in bladder cancer, the impact of cribriform morphology on prostate cancer metastasis risk, and much more. Check out the website and subscribe to the newsletter! http://www.quadshotnews.com Founders & Lead Authors: Laura Dover & Caleb Dulaney Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the limited role of axillary dissection in breast cancer, the benefits of SBRT in oligometastatic renal cell carcinoma, more data on ultra central lung cancer radiation, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the pros and cons of dose de-escalated RT for resected HPV+ oropharynx cancer, another trial showing that SBRT for oligometastatic prostate cancer improves outcomes, a model for predicting brain radiation necrosis with SRS, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the ability to skip a mediastinal nodal dissection with small GGOs, how Pluvicto improves outcomes in mCRPC with higher tumor volume, the lack of general knowledge about the link between HPV and oropharyngeal cancer, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight how intranasal mupirocin decreases radiation dermatitis associate with nasopharynx radiation, the lack of benefit of immunotherapy in MGMT-unmethylated GBM, the role of neoadjuvant chemoradiation in unresectable pancreatic cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight long term results from FLAME on DIL SIB in prostate cancer, how the benefits of Pluvicto are growing, the thought provoking question of surgical omission in breast cancer, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight de-escalated therapy for cutaneous SCC based on pembro response, a comparison of fluciclovine vs. PSMA PET scan in biochemically recurrent prostate cancer, an important change to HPV+ oropharyngeal staging, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the impact of perilesional edema on local failure risk for brain SRS, the benefits of RT in high risk prostate cancer, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast that highlights the debate over T&O or T&R, the risk of incontinence after salvage, post-prostatectomy radiation, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight a PSMA Theranostic contender, new guidelines (and name) for GBM, current management limitations in NSCLC, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this episode of the QuadCast where we highlight de-intensification for HPV mediated oropharyngeal squamous cell carcinoma, how the addition of radium 223 to enzalutamide improves outcomes, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast with many highlights from ASCO, including adding nivo to postop CRT in HNSCC, the benefits of immunotherapy in resected MMRd colon cancer, how SRS beat HA-WBRT, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight SRS vs. fSRS for hearing preservation in vestibular schwannomas, preoperative immunotherapy in HNSCC, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the predictive abilities of AI for ADT duration in prostate cancer, how consolidative chemoRT benefits patients with unresectable gallbladder cancer, the benefits of immunotherapy in clear cell GYN cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight PROSTOX's ability to predict late GU toxicity, why long course chemoradiation may be better than short course RT in rectal cancer, how to identify aggressive chromosomal alterations in meningiomas, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out the this week's QuadCast as we highlight omission of surgery in breast cancer patients, best management of small cell lung cancer, adaptive radiation for cervical cancer, the best approach for prostate brachytherapy boost, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the link between dental hygiene and oral mucositis risk, the optimal timing of post-treatment PSMA PET scans, the impressive impact of immunotherapy in MSI-high colorectal cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the role of induction chemoimmunotherapy, the scenarios where partial breast irradiation and cosmetic breast surgeries can be considered, and how the Sedlis criteria treatment paradigm remains standard for intermediate risk cervical cancer patients after surgery.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the role of staging brain MRI in metastatic breast cancer, the link between acute and late toxicity in prostate cancer treatment, the benefits of liver SBRT over TACE, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight bone SBRT guidelines, best practice in the treatment of WHO grade II meningioma, frequency of partial breast IMRT treatment, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the results of RTOG 0920 for adjuvant therapy in H&N cancer, the benefit of bone protective agents in patients receiving radium 223 + enzalutamide, the benefit of incorporating counseling into smoking cessation strategies, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight spinal cord constraints for spine SBRT, published results of RTOG 1112 where liver SBRT shines, the role of prophylactic nodal RT in prostate SBRT, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight ideal adjuvant management of endometrial cancer from GOG 258, the best approach to locally recurrent rectal cancer, and also highlight recurrent GBM management guidelines. Welcome to 2025!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the benefits of considering short course RT instead of years of endocrine therapy for low risk breast cancer patients, the superiority of SBRT over ablation for recurrent HCC, and much more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the reduced toxicity of reduced-margin MRI-guided prostate SBRT, the response rate of double hit lymphoma to radiation, the inappropriate radiation services denial rate of Medicare Advantage plans, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the oncologic benefit of extended nodal dissection for prostate cancer, the comparison of Durvalumab and Cetuximab in cisplatin-ineligible H&N cancer patients, the high incidence of psoriasis development on immunotherapy, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's Quadcast as we highlight the impact of post-prostatectomy radiation on quality of life outcomes, APBI for invasive lobular carcinoma, the disproportionate rate of depression amongst head and neck cancer patients, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we discuss if PCV is better than TMZ for oligodendroglioma, discuss results of the hypo-FLAME trial for prostate cancer, highlight adjuvant RT for high risk bladder cancer in the BART trial, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the important results of the PACE-B trial for prostate SBRT, the utility of frozen section analysis of SLN bx in oral cavity cancer, dose de-escalation for gastric MALT lymphoma, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out the latest QuadCast where we interview Jason Efstathiou at the 2024 ASTRO Annual Meeting about his Plenary Session on the PARTIQoL trial, which is a first of its kind randomized trial of IMRT vs. Proton Therapy for localized prostate cancer. Don't miss it.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out the latest QuadCast where we interview Dr. Matthew Poppe on RT CHARM about the new standard of care for post-mastectomy radiation.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this episode of the QuadCast where we speak with Sue Yom (editor of the Red Journal and PI for HN005) about the history of HPV+ oropharyngeal cancer, the current status of the data, and future directions for the field. Don't miss out as this episode is packed with great information!

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Check out this week's Quadcast as we highlight the first randomized trial of SBRT vs. Surgery for prostate cancer, the impact of pembrolizumab on survival in triple negative breast cancer, and the improved survival in limited stage small cell lung cancer with the addition of Durvalumab.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's episode of the QuadCast where we highlight short course vs. long course RT as part of TNT for rectal cancer, the cost-effectiveness of bevacizumab for radiation necrosis, an evaluation of induction chemo for elderly patients with nasopharynx cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight PET-adaptive therapy for primary mediastinal B-cell lymphoma, the benefits of cannabis extract on refractory chemotherapy-induced nausea, bladder preservation treatment strategies, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight SBRT for oligometastatic pancreatic cancer, preoperative APBI, the role of post-lumpectomy mammograms prior to RT, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the benefits or lack thereof for prophylactic contralateral mastectomy, the benefits of bone marrow sparing IMRT in cervical cancer, the best concurrent cisplatin dosing regimen for H&N cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the need for Radiation Oncology payment reform, the challenges of metaplastic breast cancer, appropriate resection margins for melanoma in situ, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the benefit of immunotherapy for nasopharynx cancer, new ASTRO guidelines for HPV+ oropharynx cancer treatment, the benefits of surgery for low grade serous ovarian cancer, the potential of PSMA PET to help with recurrent GBM, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the role of radiation for macular degeneration, IMRT in soft tissue sarcoma, SABR for GYN malignancies, the ongoing underutilization of lung cancer screening, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight major findings from ASCO 2024! Learn about immunotherapy neoadjuvantly for Stage III melanoma, the role of osimertinib in localized NSCLC, the role of short vs. long course ADT in salvage prostate treatment, and much more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's Quadcast where we highlight the role of FMISO PET to identify tumor hypoxia for attempts at dose de-escalation in HPV mediated HNSCC, ASTRO's new guidelines on bone metastasis treatment, SBRT for mediastinal LNs, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight optimal treatment for locally recurrent endometrial cancer, the use of GARD in nasopharyngeal cancer, improved survival outcomes with patient portal utilization, and more.

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Check out this week's QuadCast as we highlight a simpler approach to concurrent chemo for esophageal cancer, the importance of age in endometrial cancer, the benefits of a plant-based diet in prostate cancer, and more.

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Check out this week's Quadcast as we highlight SBRT for oligoprogressive prostate cancer, salvage SRS for high risk meningiomas, changes in breast cancer screening recommendations, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight a better RT dosing schedule for vulvar cancer, metastasis directed therapy for nasopharyngeal cancer, PSMA targeted treatments, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's episode of the QuadCast where we highlight the PFS benefit of pembro in cervical cancer, the benefit of adjuvant RT in thymic carcinoma, a novel agent for GBM, and a handy calculator for re-irradiation.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight pembro + CRT for head and neck cancer, the benefit of treating the primary tumor in NSCLC with brain mets, the potential protection of estrogen against head and neck cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out the latest QuadCast where we highlight the results of the NATALEE trial, long term CONVERT results for SCLC, Gray Matter changes after SRS for Trigeminal Neuralgia, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight omission of the low neck in nasopharyngeal radiation treatment, the benefits of HDR boost over LDR boost for prostate cancer, and more.Check out the website and subscribe to the newsletter! www.quadshotnews.com Founders & Lead Authors: Laura Dover & Caleb Dulaney Podcast Host: Sam Marcrom

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Check out this week's QuadCast where we highlight the benefits of PSMA PET, how CPAP can help breast cancer radiation treatments, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's Quadcast as we highlight hyperbaric oxygen for chronic RT side effects, optimal treatment for nasopharyngeal cancer, predictors of in-field failure in head and neck cancer, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the role of systemic therapy with SABR in oligometastatic disease, the role of immunotherapy in EGFR-mutated Stage III NSCLC, the role of mirtazepine in cancer-related anorexia, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight if testosterone replacement therapy in men with Low T affects prostate cancer risk, the combination of pyrotinib + capecitabine + brain RT, the importance of dose to pulmonary veins in the development of A-fib, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast! We highlight results of potentially practice changing B-51, published results of the CURB trial for oligoprogressive lung & breast cancer, what to do with the rare radiation refractory plasmacytoma, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight PACIFIC-2 using concurrent durvalumab in NSCLC, predictive MRI features for prostate cancer outcomes, the benefit of radiation in H&N Merkel cell carcinoma, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight why radiation therapy is important in Hodgkin Lymphoma, the fact that invasive lobular carcinoma may be sneakily more aggressive than their ductal counterparts, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight recent reporting from ESMO on best approach to potentially resectable pancreatic cancer, optimal timing of post-op radiosurgery for resected brain mets, the efficacy of dostarlimab on mismatch repair deficient tumors, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight TNT with chemoradiation to reduce the need for surgery on the OPRA trial, the safety of a laparoscopic Whipple, the dangers of HER2-targeted agents during pregnancy, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the risk of using antibody drug conjugates with brain SRS, 5 fraction APBI on consecutive days, a better way to classify perineural invasion, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight shorter duration trastuzumab for breast cancer, reduced length ADT in prostate cancer patients receiving brachy boost, head & neck location as a high risk factor in Merkel cell carcinoma, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight some of the most important data from ASTRO 2023, including SBRT for Renal Cell Carcinoma, SRS for small cell, RT instead of transplant for relapsed Hodgkin lymphoma, and more!

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's Quadcast as we highlight axillary US vs. SLNB for favorable breast cancer, if surgery should be considered for mesothelioma, liver transplant for colorectal cancer liver mets, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight best management of locally advanced cervical cancer, hypofractionated proton therapy in post-mastectomy patients, the safety of EGFR-TKI therapy with thoracic RT, and more.

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Founders & Lead Authors: Laura Dover & Caleb Dulaney

Podcast Host: Sam Marcrom

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Check out this week's QuadCast as we highlight the role of chemoimmunotherapy for brain mets, induction chemo to select best actors for p16+ oropharyngeal SCC, the role of Cialis for GBM, and more.

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Check out this QuadCast episode that features controversy of radiation omission in breast cancer, 3-fraction SRS considerations, the combination of tucatinib and SRS, the role of definitive treatment of advanced cervical cancer, and more.

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Check out the latest episode of the QuadCast where we feature omission of elective nodal radiation in H&N cancer, definitive treatment outcomes of node positive bladder cancer, serum HPV testing for OPX cancer, and more.

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Check out this week's episode of the QuadCast. We highlight more evidence for perioperative immunotherapy for NSCLC, the impact of molecular subtype on adjuvant radiation for endometrial cancer, radiosurgery for small cell lung cancer brain metastases, and more.

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Check out this week's QuadCast as we highlight the benefit of immunotherapy with SABR for NSCLC, the refreshing Common Sense Oncology Initiative, the interaction of corticosteroids and immunotherapy, and more.

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Check out the latest QuadCast where we highlight the new radiation oncology reimbursement model (ROCR) proposed by ASTRO, the role of AI in ADT predictions, dysphagia-optimized IMRT, and more.

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Check out this week's QuadCast as we highlight rectal cancer risk stratification data from OCUM, conventional vs. mod hypofrac for high risk prostate cancer, the downside of full length vaginal cylinder brachytherapy, and more.

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Check out this week's QuadCast as we highlight SIB in whole breast radiation, EBRT + brachy vs. Brachy alone for int. risk prostate cancer, the growing role of preop SRS for brain mets, and more.

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Check out this week's QuadCast as we summarize the most important results from ASCO 2023. This includes the PROSPECT trial for rectal cancer, final reporting of the ADAURA trial for NSCLC, a targeted therapeutic for IDH mutated gliomas, and much more.

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Check out the latest QuadCast episode as we highlight the benefit of PET scans in breast cancer staging, patterns of recurrence from the EORTC 22922 trial, the safety of radiation with brentuximab vedotin, the expanding role of SRS for non-malignant indications, and an interesting fact of lung cancer screening.

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Check out the latest episode of the QuadCast where we highlight the role of organ preservation in bladder cancer, the safety of lung SABR with bevacizumab, quality of life for patients undergoing watch and wait for rectal cancer, the trajectory of reimbursements in radiation oncology, and a reminder to think about tumor lysis syndrome prophylaxis.

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This week's episode of the QuadCast covers how lidocaine injection can improve breast cancer survival outcomes, the association of pathologic complete response with improved survival in soft tissue sarcoma, the role of supraclavicular lymph node dissection in breast cancer, and the beneficial effects of a preoperative exercise regimen in patients with colorectal cancer.

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The latest QuadCast episode discusses the status of Pluvicto, breast conservation therapy for patients with multifocal breast cancer, the reason that whole brain radiation has neurocognitive impact, impressive results of immunotherapy for dMMR endometrial cancer, the timing of prostate SBRT, and newly approved Narcan nasal spray. Be sure to tune in!

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Check out the latest episode of the QuadCast where we highlight the latest oncologic publications. This episode highlights the benefits of aggressive local control for intrahepatic cholangiocarcinoma, the efficacy of SABR for RCC in a prospective trial, a technique to improve oncologic outcomes for retroperitoneal sarcoma, evaluation of single vs. multi-fraction SRS regimens for meningiomas, and the thought provoking idea that radiation might mitigate the neurodegenerative decline from Alzheimer's dementia.

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Tune in to our latest episode of the QuadCast where we interview Dr. Colin Champ at the ACRO 2023 annual meeting. Dr. Champ is a Radiation Oncologist who is a leader regarding the interplay of diet and exercise as they pertain to oncology. He helps run an Exercise Oncology program and is widely published. We address the best way to exercise, the best diet to eat, the value of fasting and calorie restriction, and the importance of improving body composition. This is one of the most fascinating and exciting interviews to date. Don't miss out!

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Check out the latest Quadcast summary of the latest oncologic literature, including radiation oncology workforce evaluation, novel breast reconstruction options after mastectomy for breast cancer, new breast cancer palliative radiation options, the potential advantage of Pd-103 in LDR prostate brachy, the impact of an exercise regimen on risk of falling in breast cancer survivors, and the impact of daylight saving time on your circadian rhythm.

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Catch up on the latest in oncologic literature with summaries from the latest publications addressing hyperfractionation in re-irradiation for nasopharyngeal cancer, prostate cancer risk stratification based on post-treatment PSA, the role of PET adaptive radiation volumes in vulvar cancer, the association of antibiotics on immunotherapy efficacy, and the potential benefit of regular support emails in prostate cancer patients.

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Partial Derivative

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Yes Lecan!

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We get a chance to hear from Loren Mell of UCSD as he discusses the results of HN004, the role and timing of immunotherapy in head and neck cancer, and his thoughts on dose de-escalation in HPV driven oropharyngeal cancer. Don't miss this ASTRO 2022 interview.

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We sit down with Dr. Jonathan Tward from the University of Utah to discuss his ASTRO 2022 plenary session results, the implications of AI driven prostate cancer prognostication for patients, and the future of prostate cancer care. Don't miss this awesome episode!

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We sit down with Emily Daugherty from the University of Cincinnati to discuss the first ever clinical trial treating humans with FLASH proton radiotherapy. We dive into the details of FLASH, discuss the results of her trial, and look to the future implications of this exciting treatment technique.

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Stay up-to-date with the latest on NSCLC surgery, NSCLC systemic therapy, Hypofractionation in Endometrial cancer, online calculators, and more!

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We get a chance to sit down at the ACRO 2022 Annual Meeting with Charles Thomas & Joe Kascmar from Dartmouth to discuss mentorship, diversity, and the future of oncology.

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Check out the amazing insight that Dr. Jillian Tsai has regarding the oligoprogressive disease state (if it exists?!) as she breaks down results of her CURB trial that evaluates the role of SBRT in oligoprogressive disease for NSCLC and breast cancer.

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Check out our interview with Dan Ma as he highlights de-escalated adjuvant radiation therapy (DART) for HPV associated oropharyngeal cancer. We talk logistics, practicality, quality of life, and efficacy.

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We get a chance to sit down with Dr. Daniel Krauss to discuss RTOG 0815, modern management of intermediate risk prostate cancer, and much more. Be sure to check out the live content from ASTRO 2021.

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We sit down with David Palma at ASTRO 2021 to discuss hot topics, including ORATOR2, De-escalation in HPV-driven oropharyngeal cancer, Oligometastatic disease, and more!

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Jacob Scott from Cleveland Clinic and Javier Torres-Roca from Moffitt Cancer Center discuss their work on the Radiation Sensitivity Index (RSI), Genomically Adjusted Radiation Dose (GARD), and how their work could potentially change cancer care forever. Be sure to check out this incredible episode with some incredible guests. See the links below to their work!

https://www.jto.org/article/S1556-0864(20)31046-7/fulltext

https://www.medrxiv.org/content/10.1101/2020.12.19.20248484v3

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COVID, Cancer News, and much more.

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GTR for GBM, Transplants for Breast Cancer, COMBI-AD, Contracture, Bone Met SBRT, PD-L1>90%, MET inhibitor savolitinib, USMLE Step 1

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Lung cancer screening, Reversible Plexopathy?, LGG, ED predictors, Colorectal screening age, H. pylori family, CAR-NK cells, Thymic tumors

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Modern Dose Escalation - Esophagus, Intermediate Risk Prostate Brachy, B-cells & Immunotherapy, Coronavirus, Special K

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AI in oncology, Prostate Cancer PROs, Lymphopenia in OPX cancer, Patient Material Readability, Herceptin Hurts Hearts, Backroom Deals with China

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Talcum powder, FLAURA, Oncotype and LRR, Vegetables & Prostate Cancer, "Flu Shot", WBRT for Alzheimer's, FLASH

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Does PR status matter?, Google/DeepMind AI, Immune related rash might be good, Oligometastatic definition, Does more pounds = more life?, To SOAP or not to SOAP - a question many will face in the near future.

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Sacral SBRT, PAM 50, Protons vs. Photons, PD-1 vs. PD-L1, RO-APM unfairness

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Oncotype DX in N+ breast cancer, ADT timing, R may need less CHOP, Arimidex cancer prevention, Medical Scribes = good

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Spinal Cord Compression, B-39, RAPID, HER2CLIMB, p16+ Tonsil, Bedtime Procrastination, UnitedHealth Group makes bank

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ProtecTing the prostate, High Risk Meningioma, MRI screening for Breast Cancer, and more.....

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GBM genetics, 1p/19q, Breast Reconstruction, Prostate Brachy, NIH researcher transparency, NSCLC PETs

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Osimertinib for the win, Prostate Fossa SBRT, Fractionated Stereotactic Radiosurgery for large brain mets, IGRT Consensus, PSMA-PET, Jacksonville's Carbon

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GOG-0213, mCRPC, SBRT for cervical cancer, Rad Onc Residency Standards, AI treatment planning, Pelvic Insufficiency Fractures

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Highlights from the past week of QuadShot stories. Keeping you up-to-date with the most recent cancer news.

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Summaries of High Impact Publications from the Previous Week's QuadShot Newsletter.

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Kevin Liu on COG ANBL0532 - Does a boost to 36 Gy impact local tumor control in patients with High Risk Neuroblastoma who have gross residual disease?

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Spine SBRT constraints, HYPRO, CDDP > Cetuximab, and Psoriasis

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Prostate Nodal Radiation, Fungi, LMD, Bernie

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Prostate SBRT boost, Intratumor Heterogeneity, Twitter or Twit-him?, Wise Choices

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Immunotherapy for SCLC, Spliceosome, Heart Dosimetry, NK Cells for the Win

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Post-op SRS, CDK4/6 Survival, Titleist, RO-APM

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Rectal Cancer Chemo, AI for GI?, TILs, Deep Learning

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Breast Cancer QOL, Genome sequencing in Prostate Cancer, Healthcare Waste, ICER

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Mohs for Melanoma, SBRT and QOL, Health Benefits of Dogs, Workplace Women

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PARP paradigm, Cabazitaxel for mCRPC, Melanoma Specific Whole Brain, Melanoma Completion LND Doesn't Help

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Rectal Cancer, Targeted Therapy in CRC, Precision Medicine, IL-10

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Chemo for Sarcoma, Ferroptosis, Salvage Prostate RT, AI and fractures

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TAILORx, Gut Bacteria and ICI, HIFU Voodoo, Rehabilitation

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Post-prostatectomy RT, Palliative Care Saves Lives, Socioeconomic Status, Physician Scientists

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Prostate SBRT, PACE-B, Hyperbaric Oxygen, EPIC

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Lateral Node Dissection, PARP with a TWiST, SNPs, Pulegone

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Esophageal dose escalation, Cost neutrality, Pol Theta, Size Doesn't Matter

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Ovarian suppression, HPV, Neuroblastoma, Parental Leave Policies

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Gliomas, Opioids, Coercive Citations, Green New Deal

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Hodgkin Lymphoma, Cardiac Radiosurgery, Microbeam Radiation, PCI

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p16+ Oropharynx De-escalation, Prostate Met SBRT, Durva, Circulating Tumor HPV is Predictive

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Interview with Sue Yom discussing everything from HN-002 to the future of HPV oropharynx cancer treatment to cute puppies.

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ASTRO 2019 Highlights

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Dan Spratt talks about RTOG 9601 and his take on prostate cancer treatment.

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Oligomet Debate, Neuroblastoma, Protons for Esophagus, Suicide Risk

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Pancreas RT guidelines, Image quality, Cardiac toxicity, and Skin cancer.

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ESPAC, Stroke-like syndromes, Lung dose algorithms, RMST

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PARP-inhibitors, Metformin for Cancer, Statistical Clarity, Healthcare Policy

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TNT, VUS, Low Match Rate, Diagnostic Radiation Induced Malignancies

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Breast cancer prevention, Nomenclature consensus, Lung cancer screening, FLASH-RT

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Protons, Plant-based diets, VA Scandal, and Brexit

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Neoadjuvant Chemo in Cervical Cancer, NSCLC Oligomets, Parents' Preferences, Quality Care in Pancreatic Cancer

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Lung SBRT, OPEN access, Gender disparities, and Physician potential.

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ICI response predictions, Mitophagy, Prognosis, BRCA

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Listen to the very first QuadCast! EGFR, Alternative Payment Models, RBG, and some fun.

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