Gastroenterology: Recent Episodes
AGA
An engaging, informative mix of author interviews and expert commentary on the latest articles from Gastroenterology, hosted by the AGA journals' online editor, John F. Kuemmerle, MD, AGAF.
A review article in the April 2015 issue of Gastroenterology looks at the effects of Helicobacter pylori infection and challenges to and benefits of its eradication.
A study in the February issue of Gastroenterology looked at mucosal impedance (MI) patterns in patients with GERD and common nonreflux conditions, to assess MI patterns before and after treatment with proton pump inhibitors and to compare performance.
A review article in the January issue of Gastroenterology summarizes recent findings and highlights emerging trends in the gut–liver axis relevant to alcoholic liver disease. Dr. Kuemmerle interviews author Dr. Gyongyi Szabo
A review article in the December issue of Gastroenterology looks at current options and new advances in management of eosinophilic esophagitis. Dr. Kuemmerle speaks with the co-author of this review, Dr. Evan Dellon.
A study in the November issue of Gastroenterology shows results of a controlled randomized trial to compare the efficacy of repeated fecal immunochemical tests (FITs) and colonoscopy in detecting advanced neoplasia in family members of patients w/ CRC.
A study in the October issue of Gastroenterology estimates the risk of upper gastrointestinal bleeding during concomitant use of nonselective (ns)NSAIDs, cyclooxygenase -2 selective inhibitors (COX-2 inhibitors), and low-dose aspirin with other drugs.
A study in the September issue of Gastroenterology evaluated the effects of vedolizumab induction therapy for patients with Crohn's disease for whom tumor necrosis factor (TNF) antagonists have already failed. Dr. Kuemmerle speaks with Dr. Bruce E. Sands
Two related studies in the August issue of Gastroeneterology discuss factors that could affect colorectal cancer screening strategies, including age, sex, race, ethnicity, and whether or not repeat colonoscopy is advisable within ten years.
A study in the July issue of Gastroenterology sheds new light on adverse outcomes associated with drug-induced liver injury. Dr. Kuemmerle speaks with author Dr. Robert J. Fontana
An editorial in the June issue of Gastroenterology discusses recent findings that could help physicians and patients manage celiac disease beyond a gluten-free diet. Dr. Kuemmerle speaks with author Dr. Sheila Crowe.
An article in the May issue of Gastroenterology analyzed the UNOS database to determine the impact of the HPS MELD exception policy on outcomes of post-liver transplantation patients. Dr. Kuemmerle speaks with author Dr. David S. Goldberg
An editorial in the April issue of Gastroenterology compares anti-tumor necrosis factor monotherapy with combination therapy for inflammatory bowel disease. Dr. Kuemmerle speaks with co-author Dr. Corey A. Siegel
A study in the March issue of Gastroenterology examined the safety and efficacy of 2X daily telaprevir in treatment-naive patients with chronic HCV genotype 1 infection, including those with cirrhosis. Dr. Kuemmerle speaks to author Dr. Maria Buti.
A study in the February issue of Gastroenterology examined the safety and efficacy of an interferon-free, ribavirin-free regimen of direct-acting antivirals in patients with chronic HCV infection. Dr. Kuemmerle speaks to Dr. Gregory T. Everson.
Two studies in the January issue of Gastroenterology show that subcutaneous golimumab induces and maintains clinical response and remission in patients with moderate-to-severe ulcerative colitis; Dr. Kuemmerle speaks to Dr. Brian G. Feagan
A study in the December issue of Gastroenterology examined the relationship between low–normal and high–normal levels of alanine aminotransferase (ALT) and various cardiovascular risk factors; Dr. Kuemmerle speaks to first author Dr. M. Shadab Siddiqui
A prospective study in the November issue of Gastroenterology looked at associations between long-term intake of dietary fiber and risk of incident Crohn's disease or ulcerative colitis; Dr. Kuemmerle speaks to Dr. Ashwin Ananthakrishnan.
Two related studies in the October issue of Gastroenterology look at early administration of azathioprine in the management of patients with Crohn's disease.
A review article in the September issue of Gastroenterology takes a comprehensive look at current understanding of primary sclerosing cholangitis (PSC) and discusses important topics for future studies
A study in the August Gastroenterology found no effect of gluten in patients with non-celiac gluten sensitivity after also reducing fermentable, poorly absorbed, short-chain carbohydrates. Dr. Kuemmerle speaks to Dr. Peter GIbson
Three studies in the July issue of Gastroenterology report on the durability of radiofrequency ablation therapy for Barrett's esophagus. Dr. Kuemmerle speaks to the author of an editorial accompanying the studies, Dr. Douglas A. Corley.
An editorial in the June issue of Gastroenterology discusses the urgent need to establish a worldwide definition for acute-on-chronic liver failure (ACLF). Dr. Kuemmerle speaks to author Dr. Jasmohan S Bajaj.
This year's annual, special “13th” issue of Gastorenterology is entitled, “The Pancreas: Biology, Diseases, and Therapy.” Dr. Kuemmerle speaks to Dr. Anil Rustgi, author of a commentary in that issue on history of clinical advances in pancreatic disease.
A review article in the May issue of Gastroenterology looks at the molecular pathways involved in benign hepatocellular tumors and discusses how this basic knowledge has been progressively translated into personalized clinical care.
An editorial in the April issue of Gastroenterology looks at how the introduction of esophageal pressure topography has changed our understanding of achalasia and esophageal motor diseases. Dr. Kuemmerle speaks to author Dr. John E. Pandolfino of Northwes
. A commentary in the March of Gastroenterology takes an overview of recent differing screening recommendations from the CDC and USPSTF for Hepatitis C Virus Infection. Dr. Kuemmerle speaks to Dr. Fasiha Kanwal
A study in the February issue of Gastroenterology sought to characterize phenotypic variation in constipated patients through high-resolution anorectal manometry. Dr. Kuemmerle discusses the results with Dr. Adil Bharucha of the Mayo Clinic.
Two papers in the January issue of Gastroenterology seek to identify noninvasive tests that can evaluate patients w/ cirrhosis for complications such as portal hypertension and varices. Dr. Kuemmerle speaks to editorial co-author Dr. Guadalupe Garcia-Tsao
A study in the December issue of Gastroenterology finds that among patients with pancreatic sphincter dysfunction, biliary sphincterotomy or a combination of biliary and pancreatic sphincterotomy similarly prevent acute pancreatitis; with Dr. Gregory Cote
A study in the November issue of Gastroenterology found that postmenopausal hormone therapy was associated with an increased risk of ulcerative colitis, but not Crohn's disease. Dr. Kuemmerle discusses these findings with Dr. Andrew T. Chan.
A new population-based study in the October issue of Gastroenterology reveals a new risk-stratification biomarker panel for Barrett's esophagus. Dr. Kuemmerle speaks with author Dr. Rebecca C. Fitzgerald.
The US Multi-Society Task Force on Colorectal Cancer has revised and updated its guidelines for colonoscopy surveillance after screening and polypectomy. Dr. Kuemmerle speaks to author Dr. David A. Lieberman of Oregon Health and Science University
An article in the August issue of Gastroenterology provides consensus recommendations for management of Barrett's dysplasia and early-stage esophageal adenocarcinoma. Dr. Kuemmerle speaks w/ author Dr. Jausz Jankowski.
The MSCGE was developed by the four national GI societies to address the need for a complete and programmatic approach to the training of procedure sedation. Dr. Kuemmerle speaks to Committee Chair Dr. John Vargo about the curriculum.
Three GI societies have developed a new practice guideline for the diagnosis and management of Non-Alcoholic Fatty Liver Disease. Dr. Kuemmerle speaks to author Dr. Naga Chalasani about these recommendations.
A study in the May issue of Gastroenterology finds that cell-type–specific expression pattern of ISGs varies among patients with different IL28B genotypes and is a strong predictor of response to interferon-based treatment. Featuring Dr. Jordan Feld.
A comprehensive review article in the April issue of Gastroenterology looks at the role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis. Dr. Kuemmerle speaks to author Dr. Kenneth Cusi.
A study in the March issue of Gastroenterology examined whether mobilization of bone marrow–derived stem cells with granulocyte colony–stimulating factor (G-CSF) might promote hepatic regeneration for patients with acute-on-chronic liver failure (ACLF).
A study in the February issue of Gastroenterology assessed colorectal neoplasm detection by a next-generation sDNA test and effects of covariates on test performance. Dr. Kuemmerle speaks to first author Dr. David A. Ahlquist
Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped. Dr. Kuemmerle speaks to the first author of this study in the January issue of Gastroenterology, Prof. Edouard Louis.
An editorial in the December issue of Gastroenterology looks at the development of DAAs directed at multiple targets in the HCV life cycle and asks, “Are we ready for interferon-free treatment regimens?” Dr. Kuemmerle speaks to co-author Dr. Anna Lok
A study in the November issue of Gastroenterology looks at the risk of nonmelanoma skin cancer (NMSC) among individuals with inflammatory bowel disease (IBD). Dr. Kuemmerle speaks to study co-author Dr. Harminder Singh
A study in the October issue of Gastroenterology evaluated the prevalence of celiac disease antibodies and biopsy-confirmed CD among patients with nonconstipated IBS in a large US population. Dr. Kuemmerle speaks to author Dr. Brooks Cash.
Two studies in the September issue of Gastroenterology look at the effects of vertical sleeve gastrectomy (VSG) on plasma lipid levels and metabolism. Dr. Kuemmerle speaks to two of the co-authors of both studies.
A study in the August issue of Gastroenterology assessed long-term rates of eradication, safety, and durability of radiofrequency ablation in patients with Barrett's esophagus. Dr. Kuemmerle speaks to author Dr. Nicholas Shaheen of UNC Chapel Hill
Two studies in the July issue of Gastroenterology examine the relationship between fruits, vegetables, folate, and colorectal cancer, and suggest that potential associations are more complex than first considered. Dr. Kuemmerle speaks to Dr. Andrew Chan
A review in the June issue of Gastroenterology discusses the effects of autophagy on hepatic and pancreatic physiology, and the contribution of this degradative process to diseases of the liver and pancreas. Dr. Kuemmerle speaks with author Dr. Mark Czaja
A study in the May issue of Gastroenterology examines the influence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large prospective cohort. Dr. Kuemmerle speaks w/ author Dr. Lisa Strate of the University of Washington
A comprehensive review on recent findings about the clinical features, diagnosis, epidemiology, pathophysiology, and treatment of microscopic colitis appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with co-author Dr. Darrell S. Pardi.
The AGA releases its medical position statement and technical review on the management of Barrett's esophagus in the March issue of Gastroenterology. Dr. Kuemmerle speaks with a co-author of both documents, Dr. John Inadomi.
A study in the February Gastroenterology looks at changes in insulin resistance and weight in patients with chronic hepatitis C during and after peginterferon and ribavirin therapy. Dr. Kuemmerle speaks with lead author Dr. Hari S. Conjeevaram.
An important study in the January Gastroenterology looks at the prevalence of NAFLD and NASH among a group of patients utilizing ultrasound and liver biopsy. Dr. Kuemmerle speaks with author Dr. Stephen A. Harrison.
A Pyrosequencing study of twins in the December Gastroenterology looked at the role of gastrointestinal microbiota in the etiology of IBD. Dr. Kuemmerle interviews author Dr. Lars Engstrand
A study in the November issue of Gastroenterology investigates whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance colonoscopies is associated with advanced neoplasia.
Dr. Kuemmerle speaks to co-author Dr. David Metz about a review article in the October 2010 Gastroenterology on safety of proton pump inhibitor exposure.
The authors of a study in the September issue of Gastroenterology explored the temporal association between cough and gastroesophageal reflux (GOR) in patients in whom non-GOR causes have been excluded.
Achalasia is the subject of a mini-review in the August issue of Gastroenterology. Dr. Kuemmerle speaks to author Dr. David Katzka. Also, a new feature on the latest stories from GI and Hepatology News.
A prospective study to determine the clinical, pathologic, and serologic spectrum of celiac disease in a general population appears in the July issue of Gastroenterology.
A study in the June 2010 issue of Gastroenterology looks at gastroesophageal variceal formation and progression in a large cohort of patients with chronic hepatitis C and advanced fibrosis. Dr. Kuemmerle speaks with author Dr. Robert J. Fontana.
Dr. Kuemmerle speaks with Dr. James E. Allison about his article in the May issue of Gastroenterology on colorectal cancer screening guidelines and deciding which test to recommend.
A critical review of new diagnostic and treatment innovations for pelvic floor disorders appears in the April issue of Gastroenterology. Dr. Kuemmerle speaks with author Dr. Adil E. Bharucha.
A study in the March issue of Gastroenterology compares probe-based confocal laser endomicroscopy (pCLE) virtual chromoendoscopy for classification of colon polyps. Dr. Kuemmerle speaks to author Dr. Michael Wallace
An AGA medical position statement and technical review on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease appear in the February 2010 issue of Gastroenterology. Dr. Kuemmerle speaks with author Dr. Francis A. Farraye.
A study in the January 2010 Gastroenterology assesses long-term clinical outcomes of Hepatocellular carcinoma patients treated with intra-arterial yttrium-90 microspheres. Dr. Kuemmerle speaks to senior author Dr. Riad Salem.
A study in the December 2009 Gastroenterology looks at factors that predict response of patients with chronic hepatitis B virus (HBV) infection to therapy with pegylated interferon (PEG-IFN)–alfa.
A study in the November 2009 Gastroenterology looks at a possible alternative concept for the development of reflux esophagitis.
A study in the October 2009 Gastroenterology compares colectomy rates following treatment of ulcerative colitis with placebo or infliximab
Dr. Don Rockey discusses current perspectives and future directions of computed tomographic (CT) colonography
A new study by Dr. Fred Gorelick examines whether or not exposure to an acid load might sensitize the acinar cell to secretagogue-induced pancreatitis.
A study in the August 2009 issue of Gastroenterology set out to estimate the prevalence of different types and frequencies of fecal incontinence, describe demographic f
Dr. Kuemmerle speaks with Dr. John Inadomi, author of a study in the June issue of Gastroenterology that compares the cost utility of ablation with that of endoscopic surveillance strategies.
Dr. Kuemmerle interviews Dr. Jeffrey Schwimmer, lead author of an article in the May Gastroenterology that studies the role of familial factors in identifying individuals at high risk for NAFLD. The second of two Gastroenterology podcasts for May 2009.
Dr. Kuemmerle speaks with Dr. Henry Parkman and Dr. Michael Jones, authors of a fascinating review article in the May Gastroenterology that describes tests of gastric function , provides the methodologies behind them and details the physiology that they a
The authors of a study in the April issue of Gastroenterology have developed a clinical prediction rule for recurrent Clostridium difficile infection (CDI) that identifies high-risk patients likely to benefit from preventive measures against recurrence.
Dr. Kuemmerle, Dr. Emmet Keeffe and Dr. Michael W. Fried discuss study results that show the combination of nitazoxanide, peginterferon alfa-2a, and ribavirin improved percentages of patients with rapid virologic response (RVR) and sustained ...