Reading Time: 3 minutes The Science Show on ABC Radio National in Australia, features an interview with Professor Justin Yerbury on Saturday 17th August. The article containing the interview titled ‘Resistant nerves could lead to treatment for neurodegenerative disease‘ is a fascinating insight into Prof Yerbury’s work on the delicate balance of proteins in solution within our nerves and…
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Reading Time: 5 minutes Despite the winter chill, there is a warm fuzzy feeling today with the news of a paper published in the journal ‘Brain’ by an MND Association funded Research Fellow, Dr Scott Allen. Based at the Sheffield Institute for Translational Neuroscience (SITraN), Dr Allen was awarded a Senior Non-Clinical Research Fellowship by the Association in 2016,…
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Reading Time: 5 minutes There has recently been a flood of news stories on the outcomes of the Australian Phase 1 clinical trial investigating Copper ATSM (CuATSM) which is a small man-made compound that can selectively deliver copper to cells. The results were first presented at our International Symposium in Glasgow back in December. MND is a terrible disease…
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Reading Time: 3 minutes Love them or loath them, the band Steps’ first single ‘5,6,7,8’ was a techno line dance song released in 1998 from their debut album ‘step one’, with the B side ‘words of wisdom’. Using this forced and purely tenuous link and an equally awkward segue, I would like to share with you the news that…
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Reading Time: 5 minutes ‘Big data’ projects require detailed analysis of unimaginably large volumes of complex data. This is especially true in the realm of MND gene discovery when searching for MND-associated genes – where the greater the number of samples analysed, the greater the possibility of finding the relatively less frequently occurring genetic causes (known as ‘rare’ variants).…
The post Collaboration and Consortium Cracking the Code: Uncovering KIF5A – MND gene appeared first on MND Research Blog.
Reading Time: 6 minutes A new model of MND in mice made using CRISPR technology to edit TDP-43. The mice have cognitive changes and have uncovered new insights into MND- FTD mechanisms.
The post Mice and Marbles: A CRISPR Model of Motor Neurone Disease appeared first on MND Research Blog.