Listen to The Lancet Respiratory Medicine: Recent Episodes
The Lancet Respiratory Medicine
The Lancet Respiratory Medicine publishes a range of article types in respiratory medicine and critical care. These include Original Research, Reviews, Personal Views, Comments, and News articles. Topics include but are not limited to asthma, COPD, tobacco control, critical care, lung cancer, cystic fibrosis, pneumonia, sarcoidosis, mesothelioma, sleep medicine, and respiratory infections.
Il Professor Sergio Harari commenta i risultati di un trial clinico di fase 2 volto a valutare l’attivita’ e la sicurezza del farmaco nintedanib come trattamento in pazienti affetti da linfangioleiomiomatosi (LAM).
Professor Sergio Harari joins us to discuss the results of a phase 2 clinical trial evaluating activity and safety of nintedanib in people with lymphangioleiomyomatosis (LAM).
Dr Robert Kullberg joins us to discuss his Viewpoint on empiric antibiotic therapy for sepsis and the importance of reducing unnecessary use of anti-anaerobic antibiotics.
Professor Heather Zar joins The Lancet Respiratory Medicine to discuss early-life RSV disease and long-term respiratory health. This topic will be covered in one of four Series papers in a cross-journal Series with The Lancet.
Professor James Hull joins us to discuss his recent Spotlight on protecting the respiratory health of athletes ahead of the Summer Olympics and Paralympics.
Dr Anne Chang discusses the burden of chronic respiratory diseases in Indigenous people.
Professor Daniel Steinfort and Professor Shankar Siva discuss the effect of systematic endoscopic mediastinal staging on radiotherapy field planning in patients with locally advanced non-small-cell lung cancer.
Prof Daniel Prieto-Alhambra, Dr Annika Jödicke, and Dr Martí Català discuss the effectiveness of COVID-19 vaccines to prevent Long COVID, estimated to affect up to 20% of those infected with SARS-CoV-2.
Dr Tim Nicholson and Dr Sarah Gorst discuss the development of an international Delphi consensus study on a core outcome measurement set for long COVID and how it will be used to inform future research and clinical care.
Dr Betty Raman discusses multiorgan MRI findings in patients after hospitalisation with COVID-19.
Prof Richard Costello discusses the use of digital measurements of medication adherence and lung function to guide management of uncontrolled asthma.
Dr Keiju Aokage discusses segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less.
Carol Hodgson discusses recent advances in our understanding of in-hospital and post-discharge outcomes in critically ill patients who receive ECMO.
Emma Grainger, Editor-in-Chief of The Lancet Respiratory Medicine, discusses the January issue and plans to celebrate the 10-year anniversary of the journal.
Vivienne Kahlmann and Catharina Moor discuss a study looking at online mindfulness-based cognitive behaviour treatment to address fatigue associated with sarcoidosis.
Yves Lacasse joins The Lancet Respiratory Medicine to discuss a meta-analysis on the effectiveness of home oxygen use for patients with COPD.
Rachael Evans discusses the needs of people with long COVID and the latest findings from the PHOSP-COVID study.
Daniel Munblit and Dale Needham discuss the importance of developing a core outcome set for post-COVID-19 condition.
Daiana Stolz discusses antibiotic stewardship in patients hospitalised with pneumonia and at risk of Gram-negative bacterial infection.
Dr Ablo Wachinou discusses the prevalence of sleep disordered breathing in Benin and how awareness and treatment might be improved.
Professor Peter Openshaw and Dr Felicity Liew discuss the use of inhaled corticosteroids in the early treatment of COVID and the involvement of the respiratory mucosa in response to viral infection.
Dr Dinh Bui discusses the association between very-to-moderate preterm birth and lung function deficits and COPD at age 53.
Ruvim Izickson discusses the safety and immunogenicity of administering a high-dose quadrivalent influenza vaccine together with a third dose of the Moderna COVID-19 vaccine in adults aged 65 years and older.
Wisia Wedzicha discusses findings of a trial of a vaccine for the prevention of COPD exacerbations and provides her insights for future research.
Eileen Rubin, author of a paper on advancing precision medicine for acute respiratory distress syndrome discusses her delayed diagnosis and how clinician and researcher goals can differ from those of patients.
Daniel Altmann discusses the duration of immune protection from COVID vaccination and the crucial implications for the implementation of booster vaccination programmes.
Comment author Michael Kreuter discusses a series of papers published in the Lancet and the Lancet Respiratory Medicine on interstitial lung disease.
Bairbre McNicholas and Jie Li discuss an open label superiority meta-trial looking at the efficacy of awake prone positioning for patients with COVID-19 acute hypoxaemic respiratory failure.
Charles Sprung and fellow co authors Christiane Hartog, Joseph Nates, and Gavin Joynt discuss the Ethicus-II study, which looked at differences in end-of-life care in nearly 200 ICUs across 36 countries.
Christopher Brightling discusses the effect of blocking thymic stromal lymphopoietin (TSLP) with tezepelumab in patients with moderate-to-severe uncontrolled asthma.
Dr. Paul Verweij discusses a Personal View published in TLRM on COVID-19 associated aspergillosis.
Dr. Ignacio Rubio discusses a comprehensive review of the pathophysiology and phenotypes of COVID-19, the first in a Series of four papers about the pathophysiology of acute disease.
Dr. Kiran Shekar discusses a randomized controlled trial looking at cytokine adsorption in patients with severe COVID-19 pneumonia.
Dr Fan Chung discuses confronting COVID-19-associated cough and the post-COVID syndrome.
Dr. Joseph Han discusses the results of the phase III SYNAPSE trial, evaluating the efficacy and safety of mepolizumab in patients with chronic rhinosinusitis
Dr. Mona Bafadhel discusses the STOIC trial, which looked at the use of inhaled budesonide in the treatment of early COVID-19.
Dr. Arvinder Soin discusses the use of tocilizumab plus standard care versus standard care alone in the treatment of moderate to severe COVID-19-associated cytokine release syndrome.
Jordan Feld discusses the use of peginterferon-lambda in the treatment of ambulatory COVID-19 patients.
Rishi Gupta discusses a model to evaluate and predict the risk of clinical deterioration in patients with acute COVID-19
Toby Maher discusses the results of the SENSCIS trial, looking at the safety and efficacy of nintedanib in systemic sclerosis-associated interstitial lung disease (SSc-ILD) treated with mycophenolate.
Dr. Catherine Quantin discusses a new study looking at the ways severe influenza and COVID-19 are similar and differ.
Dan Lewer of University College London discusses a modelling study that looks at housing strategies for homeless populations in the UK during COVID-19.
Dr. Anna Schultze discusses inhaled corticosteroid use in COPD and asthma patients and whether they have either a protective or harmful effect when related to COVID-19
Richard Beasley discusses a Series of three papers in The Lancet and The Lancet Respiratory Medicine that consider the promise of novel strategies to drive down the global burden of asthma.
Dr. Reagan-Steiner and Dr. Gary about pathlogical findings in suspected cases of e-cigarette, or vaping, product use-associated lung injury, or EVALI.
Dr. Tina Hartert discusses a new study that aimed to evaluate the strength for a causal effect of Respiratory Syncytial Virus-Lower Respiratory Tract Infection (RSV-LRTI) in subsequent chronic wheezing illness to inform public health expectations for RSV vaccines.
Authors of a new population-based study on the association between antibiotic use in infancy and risk of asthma later in life discuss the results of their trial and how they might influence paediatricians and parents.
David Maslove and Daniel E. Leisman discuss their recent paper published in Critical Care Medicine discussing guidance on the development of prediction models for critical care
Don Sin discusses a new tool for clinicians to use to detect potential exacerbations in patients with chronic obstructive pulmonary disorder.
Authors of the MERGE Trial discuss treatment of mild obstructive sleep apnea and the effectiveness of continuous positive airway pressure, or CPAP, in the treatment of patients with mild OSA
Authors from a new case series talk about the development of an algorithm they developed for the diagnosis and treatment of e-cigarette or vaping product use-associated lung injury, or EVALI.
Dr. Marcelo Cypel discusses a trial looking at lung transplantation from Hepatitis C viremic donors.
Dr Scott Bell and Dr Felix Ratjen discuss The Lancet Respiratory Medicine's Cystic Fibrosis Commission on the future of cystic fibrosis care.
Dr. Luca Richeldi discusses a trial looking at pamrevlumab, an anti-connective tissue growth factor therapy for the treatment of idiopathic pulmonary fibrosi
Dr. Natalie Walker discusses a trial she and her colleagues conducted looking at the effectiveness of nicotine patches used in conjunction with e-cigarettes for smoking cessation.
Grant Theron discusses growing evidence of the importance of the lung and gut microbiomes in tuberculosis, and how this knowledge might affect the future of treatment.
Dr Vikas Goyal discuses the use of oral antibiotic treatment in non-severe exacerbations of bronchiectasis in children.
Dr Gabriel Loor discusses a new study looking at how the normothermic portable Organ Care System works to improve donor lungs for transplantation.
Alex Franciosi talks with The Lancet Respiratory Medicine about the pitfalls and caveats of testing for α1-antitrypsin deficiency.
Thushan de Silva, from the Medical Research Council Unit in The Gambia, discusses a new study looking at the immunogenicity of live-attenuated influenza vaccines among children in The Gambia.
Dr Annette Peters addresses the current debate about the science behind European air quality standards, and why ambient air pollution deserves serious attention.
Dr John Myburgh discusses a reanalysis by Levin and colleagues of the FEAST trial, which looked at the adverse effects of the administration of saline or albumin fluid bolus in resuscitation.
Use of intensive care unit (ICU) resources in the USA outpaces the rest of the world. The Lancet Respiratory Medicine spoke with Dr James Downar about why ICU usage in the USA is so high, what that means for care, and what can be done about it.
François Maltais and Yohan Bossè discuss their investigation of five generations of a French-Canadian family with multiple recurring cases of early emphysema.
Dr. Warren Lenney calls for global children’s charter focusing on the diagnosis and treatment of childhood asthma globally
Fabien Maldonado discusses the effectiveness of pleural manometry to monitor pleural pressure during thoracentesis procedures.
Professor Pallav Shah discuses surgical and endoscopic interventions that reduce lung volume for emphysema.
Dr Raj Gupta discusses the potential of delaminid, one of the first new TB drugs to enter the market in 40 years, to offer new hope for treatment of multi drug resistant tuberculosis.
Ben Cowling discusses his work in Hong Kong investigating the effectiveness of the flu vaccine over time.
To mark World Pneumonia Day, The Lancet Respiratory Medicine talks with Stefano Aliberti about his Comment calling for international action to tackle pneumonia.
Simon Walsh discusses the potential for machine learning-assisted diagnosis of fibrotic lung disease.
Carolyn Calfee joins The Lancet Respiratory Medicine to discuss precision medicine approaches to acute respiratory distress syndrome, or ARDS.
Bart Rijnders joins The Lancet Respiratory Medicine to discuss his new paper on patients with severe influenza developing invasive pulmonary aspergillosis.
Jennifer Furin joins The Lancet Respiratory Medicine to discuss the use of bedaquiline to combat multi-drug resistant tuberculosis in South Africa.
Tillie Hackett joins The Lancet Respiratory Medicine to discuss her study assessing small airways in chronic obstructive pulmonary disease.
Julian Forton joins The Lancet Respiratory Medicine to talk about his new study into lower airway bacterial sampling in young children with cystic fibrosis.
Dr. Diana Bilton joins The Lancet Respiratory Medicine to discuss how the use of rare disease patient registries helps with long term drug studies after drug authorisation.
Allan Glanville joins The Lancet Respiratory Medicine to discuss the INSPIRE trial that assesses the use of the Portable Organ Care System to reduce primary graft dysfunction in bilateral lung transplantation.
Keertan Dheda joins The Lancet Respiratory Medicine to discuss the hottest topics in TB control and treatment.
Valerie Page joins The Lancet Respiratory Medicine to discuss the new themed issue on the subject of critical care.
Mike Thomas talks about his trial of self-taught breathing retraining as a treatment for asthma.
Alvar Agusti discusses his study investigating low lung function in early adulthood and the effects this has on future health.
Michael Kreuter highlights the importance of palliative care for patients with interstitial lung disease.
Adrian Martineau discusses his meta-analysis of individual patient data assessing whether vitamin D supplementation can help prevent asthma exacerbations.
Mona Bafadhel discusses her work on using eosinophils as biomarkers in chronic obstructive pulmonary disease.
Valerie Page discusses the use of a statin, simvastatin, to help patients with delirium in the intensive care unit.
Daniele de Luca discusses his Position Paper, the first to provide a consensus definition of acute respiratory distress syndrome in neonates.
John Laffey discusses his geo-economic analysis of the LUNG SAFE study, and its implications for global clinical practice.
2017 marks the 50th anniversary of the first description of acute respiratory distress syndrome in a study published in The Lancet. To mark this, The Lancet Respiratory Medicine’s June issue is themed around ARDS and critical care. Here, TLRM's Laura Feetham talks to Michael Matthay about recent advances in the field of ARDS.
Aaron van Dorn speaks with March for Science co-chair Jonathan Berman and march participant Elliott Haut, a trauma and critical care surgeon, about politics and science.
To mark World TB Day and the launch of a major new commission on drug-resistant tuberculosis, The Lancet Respiratory Medicine's April issue is about TB. In this podcast, Aaron van Dorn interviews Stephen Gillespie about the special issue
Robert Hyzy talks to Laura Feetham about how to encourage critical care doctors to stop employing ineffective practices.
Simon Hart provides an overview of the January issue of The Lancet Respiratory Medicine, which focuses on idiopathic pulmonary fibrosis.
Melissa McDonnell discusses a new index used to predict mortality and disease outcomes for patients with bronchiectasis.
Marcelo Cypel discusses his findings on the use of ex-vivo lung perfusion in preserving transplantable lungs.
Professor Wayne Hall talks about the challenge of reducing smoking in people with serious mental illness.
Professor Jane Davies discusses current trends in cystic fibrosis detection and treatment.
Donald Tashkin discusses a clinical trial for the treatment of scleroderma-related interstitial lung disease, a rare but devastating condition.
Dr. Theodore "Jack" Iwashyna discusses the differences between the treatment of patients with acute critical illness and persistent critical illness.
Dr. Dirkje Postma of the National Program of Lung Research discusses the changing face of pulmonary disease research.
Michael Kreuter discusses a pooled analysis of data on the role of antacid therapy in the progression of idiopathic pulmonary fibrosis.
Marius Hoeper and Patricia Lobo discuss the global burden of pulmonary hypertension, and options for treatment.
Robert Dickson discusses the role of microbiome and the care and treatment of critically ill patients.
Ulrike Gehring discusses the link between air pollution and asthma in childhood and adolescence.
David Price discusses a UK cohort study into the use of blood eosinophil count as a predictor of asthma exacerbations.
Håvard Skjerven and Karin Lødrup Carlsen discuss their follow-up study to the bronchiolitis ALL trial, which suggests that giving inhaled epinephrine for acute bronchiolitis in children does not confer benefit, even for those at risk of allergic disease.
Timothy Kidd discusses the results of a social network analysis to investigate the spread of Pseudomonas aeruginosa infection in patients with cystic fibrosis.
Jose Luis Lopez-Campos discusses the heterogeneity of COPD exacerbations and proposes a new approach for treatment.
Jean-Louis Vincent, Lance Michell, and Pravin Amin discuss country-specific attitudes and approaches to the withdrawing of life-support.
Joan Soriano discusses the ability of the GOLD 2007 and 2011 staging systems to predict mortality.
David Hansell discusses uses of serial CT in drug trials for IPF, and in clinical management of the disease.
Targeting interleukin 5 for eosinophilic asthma – discussion with Jean Bousquet and Richard Lane.
Emma Grainger and Richard Lane discuss highlights from the first two years of The Lancet Respiratory Medicine
Ekaterina Kurbatova and Peter Cegielski examine culture conversion as a patient-level predictor of success at end-of-treatment in patients with MDR tuberculosis
Michael Matthay and Jennifer Wilson discuss the potential of mesenchymal stem cells for the treatment of ARDS
Adrian Martineau discusses a trial investigating whether vitamin D supplementation reduces the incidence of moderate or severe COPD exacerbations and upper respiratory infections.
Irene Higginson discusses an RCT on a new palliative care intervention for patients with chronic lung disease.
Sue Cooper discusses new findings from the SNAP trial, which assesses the effect of nicotine replacement therapy in pregnancy on early childhood development.
Bianca Schaub discusses a Review of immune mechanisms and the development of childhood asthma.
Jennifer Verani discusses the effectiveness of ten-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in Brazilian children.
James Jackson discusses the BRAIN-ICU study and explains why one in three intensive care survivors develop depression.
Markus Maeurer discusses the Tuberculosis 2014 Series, which features papers from The Lancet Respiratory Medicine and The Lancet Infectious Diseases.
Tim Dehnel is joined by Judith Nelson and Elie Azoulay to discuss whether intensive care medics should also be palliative specialists.
Victor Ortega discusses the effect of rare ADRB2 variants of risk on severe asthma exacerbations in patients receiving treatment with LABAs.
Geoff Bellingan discusses the effect of intravenous-beta-1a on lung CD73 expression and on ARDS mortality.
Klaus Rabe discusses a study that looks at ADRB2 polymorphisms and drug efficacy in preventing COPD exacerbations in patients from the POET trial.
Stefano Guerra discusses whether club cell secretory protein concentrations predict all-cause and cancer specific mortality in adults.
Clive Page discusses the effects of a novel drug, RPL554, as a bronchodilator and anti-inflammatory drug.
Professor Ganesh Raghu discusses the diagnosis of chronic hypersensitivity pneumonitis in patients with idiopathic pulmonary fibrosis.
Valerie Page discusses the effect of intravenous haloperidol on duration of delirium and coma in critically ill patients.
Jonathan Peter discusses an Article which compares two tuberculosis screening methods in a primary care setting in South Africa.
Dr. Marcelo Cypel discusses a Review on donor management and lung preservation for lung transplantation.
Andres Esteban discusses an article about the chronology of histological lesions in acute respiratory distress syndrome.
Emma Grainger discusses the launch of the inaugural issue of The Lancet Respiratory Medicine.
Claus Vogelmeier discusses a study comparing two types of inhalers for chronic obstructive pulmonary disease (COPD).