Allergy and Clinical Immunology: Recent Episodes
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Guest: Kathleen M. Buchheit, MD
Guest: Joseph K. Han, MD
Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with a low quality of life and increased healthcare utilization,1,2 and patients often continue to have severe symptoms despite therapy.3 Understanding the role of underlying inflammatory pathways and epithelial dysfunction may help inform clinical decision making for these patients.3,4 In this program, Dr Kathleen Buchheit and Dr Joseph Han share their insights on the pathophysiology of CRSwNP and how unaddressed underlying inflammation may contribute to a variety of challenges for patients. Dr Buchheit is an Assistant Professor of Medicine at Harvard Medical School, specializing in Allergy and Immunology. Dr Han is a Professor of Otolaryngology, the Chief for the Division of Rhinology and Endoscopic Sinus and Skull Base Surgery, and the Chief of the Division of Allergy at Eastern Virginia Medical School in Norfolk, Virginia.
References:
- Mullol J, et al. J Allergy Clin Immunol Pract. 2022;10:1434-1453.e9
- Bhattacharyya N, et al. Laryngoscope. 2019;129:1969-1975.
- van der Veen J, et al. Allergy. 2017;72:282-290.
- Laidlaw TM, et al. J Allergy Clin Immunol Pract. 2021;9:1133-1141.
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US-96000 Last Updated 12/24
In this brief video, learn more about growing evidence supporting the key role of airway epithelium dysfunction in driving inflammation in CRSwNP.
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US-94728 Last Updated 1/25
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Stephen I. Pelton, MD
In the last two pre-pandemic flu seasons, approximately half of hospitalizations from influenza in the US were in adults 65 and older.1,2 A recent real-world study evaluated the relative effectiveness of adjuvanted influenza vaccine versus high-dose vaccine in preventing test-confirmed influenza hospitalizations in this age group across three flu seasons between 2017 and 2020.3 Dr. Charles Turck sits down with Dr. Stephen Pelton, an author on this study, to explore the findings and their implications for influenza vaccination strategies in older adults. Dr. Pelton is a Professor of Pediatrics at the Boston University Chobanian and Avedisian School of Medicine.
References:
- Pelton SI, Nguyen VH, Mould-Quevedo JF. The value of influenza vaccination in the older adult population. A stochastic model estimation of the benefit of vaccination to prevent the severe outcomes in the U.S. Poster presented at: IDWeek 2023; October 11-15; Boston, MA.
- Pelton SI, Mould-Quevedo JF, Nguyen VH. The impact of adjuvanted influenza vaccine on disease severity in the US: a stochastic model. Vaccines. 2023;11:1525.
- McGovern I, Chastek B, Bancroft T, et al. Relative vaccine effectiveness of MF59-adjuvanted vs high-dose trivalent inactivated influenza vaccines for prevention of test-confirmed influenza hospitalizations during the 2017-2020 influenza seasons. Int J Infect Dis. …
Guest: Ryan Maves, MD
Guest: Susan Corbridge, PhD, APRN, ACNP-BC, FAANP, FCCP, FAAN
Although there have been several advances in vaccine technology and safety the past few years, the prevalence of vaccine hesitancy among patients is increasing. Since vaccine hesitancy heightens the burden of potentially life-threatening viruses like RSV and influenza, Dr. Ryan Maves speaks with Dr. Susan Corbridge about why patients might be reluctant to get vaccinated and how we can use the First 5 Minutes approach to provide individualized counseling on the importance of vaccines. Dr. Maves is a Professor of Medicine and Anesthesiology in the Sections of Infectious Diseases and Critical Care Medicine at the Wake Forest University School of Medicine, and Dr. Corbridge is a Professor Emerita at the University of Illinois at Chicago College of Nursing.
This episode is supported by an educational grant from Moderna.
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA
Guest: Alissa Kanowitz, Founding Member Families Fighting Flu
Mrs. Alissa Kanowitz became a patient advocate after experiencing the absolute worst-case scenario: losing her four-year-old daughter Amanda to the flu. And now, she’s here with Dr. Mary Katherine Cheeley to share her and Amanda’s story as well as her experience working with the Families Fighting Flu organization. This is so we can all better understand the seriousness of influenza and work to stem the tide on this tragic disease.
Guest: Paul Hunter, MD
The Advisory Committee on Immunization Practices (ACIP) recently updated their recommendations for the 2024-2025 flu season. Here to give us a breakdown of the key updates so we can protect our patients from the flu is family medicine physician Dr. Paul Hunter.
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA
Guest: Jill Foster, MD
Guest: John Russell, MD
According to recent studies, co-administering the flu, RSV, and COVID-19 vaccines is generally safe, which is why both the CDC and Advisory Committee on Immunization Practices support this approach. However, there are some important considerations to keep in mind when co-administering these three respiratory vaccines, which is why Dr. Mary Katherine Cheeley speaks with Drs. Jill Foster and John Russell about best practices for co-administration and improving vaccination rates. Dr. Foster is the Director of the Division of Pediatric Infectious Diseases at the University of Minnesota Medical School, and Dr. Russell is a family medicine physician at Jefferson Health System in Abington, Pennsylvania.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: John Russell, MD
According to the CDC, flu vaccine coverage for all adults is about 47 percent, and there’s been a continued decline among pregnant patients and children since 2020. These reduced vaccination rates can have serious consequences for our patients and the healthcare system as a whole, which is why it’s so important for primary care providers to embrace their role in reversing this trend. To help in this mission, Dr. Charles Turck speaks with family medicine physician Dr. John Russell about strategies for boosting flu vaccination rates in the primary care setting.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Laila Woc-Colburn, MD, DTM&H, FACP, FIDSA
Since annual flu shots help alleviate the severe disease burden on patients and the healthcare system as a whole, it’s important to make flu vaccination a part of every patient visit. Fortunately, tools like appointment reminders, in-office discussions, and infographics can help us integrate this preventative measure into routine patient care and protect them from the flu. To learn more about these strategies, Dr. Charles Turck speaks with Dr. Laila Woc-Colburn, Associate Professor at the Emory University School of Medicine in Atlanta.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Darvin Scott Smith, MD
Vaccines play a crucial role in preventing the flu itself, but there are a lot of lesser-known benefits of flu vaccination as well, including its impact on reducing illness severity, hospitalization rates, and co-infections as well as its importance in managing chronic diseases and enhancing public health outcomes. Joining Dr. Charles Turck to examine the comprehensive advantages of flu vaccination is Dr. Darvin Scott Smith, who’s an infectious disease consultant at San Mateo Medical Center in California.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: David Hamer, MD
Cases of chikungunya have risen significantly in recent years, but fortunately, there are several ways we can protect our patients traveling abroad, including with a novel vaccine and other anti-mosquito measures. Joining Dr. Charles Tuck to discuss key preventive strategies for the chikungunya virus is Dr. David Hamer, Professor of Global Health and Medicine at the Boston University School of Public Health.
Host: Robert Walker, PharmD
Guest: Nic Garner, PharmD
Travel vaccines are becoming increasingly common as they play a key role in protecting travelers abroad, but they’re only effective if patients actually receive them. That’s why Dr. Robert Walker speaks with Dr. Nic Garner, who shares best practices for counseling patients on travel vaccines. Dr. Garner is the District Support Pharmacist Leader at CVS Pharmacy in Texas with more than 10 years of community pharmacy management experience.
Host: Jody Takemoto, PhD
Guest: Donald Y. Leung, MD, PhD
There’s currently no way of knowing who’s going to develop a food allergy and who isn’t, which means early treatment or even prevention can't begin. But that might all change based on a recent study, which found that skin biomarkers may be able to predict the development of food allergies in pediatric patients. Here with Dr. Jody Takemoto to talk about these findings and their potential implications on food allergy care and prevention is Dr. Donald Leung, Head of Division of Pediatric Allergy and Immunology at National Jewish Health in Denver, Colorado.
Guest: Lillian Siu, MD, FRCPC
With a few studies in the works for cancer vaccines, the future is exciting for what this could mean for oncology patients. Dive in to learn about the various ways to package cancer vaccines so they can be delivered to patients effectively. And to learn more about the limitations, targets, and platforms of cancer vaccines, which was the topic of her presentation at the American Society of Clinical Oncology 2024 Conference, hear from Dr. Lillian Siu, Senior Medical Oncologist at the Princess Margaret Cancer Centre and Professor of Medicine at the University of Toronto.
Guest: Lillian Siu, MD, FRCPC
Since cancer vaccines have been of interest to oncologists for decades, they’ve been trying to figure out how to prime or stimulate the immune system to attack cancer, and until the last few years, cancer vaccines have been challenging. To learn about this unique area of study, which she also presented at ASCO 2024, join Dr. Lillian Siu, Senior Medical Oncologist at the Princess Margaret Cancer Centre and a Professor of Medicine at the University of Toronto.
Guest: Adam Narloch
Guest: Michelle Hermiston, MD, PhD
Adam Narloch speaks with Dr Michelle Hermiston to discuss the history of hemophagocytic lymphohistiocytosis (HLH) and advances in understanding this rare disease. Dr Hermiston is a pediatric hematologist-oncologist, a bone marrow transplant specialist, and the Director of the Pediatric Immunotherapy Program at UCSF Benioff Children’s Hospital. Join us as we start our journey into the world of HLH!
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Host: Cem Akin, MD, PhD
Guest: Daniel J. DeAngelo, MD, PhD
New tyrosine kinase inhibitor (TKI) treatment options can significantly reduce symptom burden in patients with moderate to severe indolent systemic mastocytosis (ISM). Studies report that systemic mastocytosis and ISM are often undiagnosed for years. Improve your diagnosis and treatment of ISM by tapping into the expertise of a multidisciplinary team, including allergists, gastroenterologists, and hematologists, and increase your awareness of diagnostic criteria, the varied presentations of ISM, and new treatment options that move beyond traditional anti-mediator therapy.
Host: Cem Akin, MD, PhD
Guest: Daniel J. DeAngelo, MD, PhD
Guest: Matthew J. Hamilton, MD
Patients with indolent systemic mastocytosis frequently report a symptom burden disproportionate to measurable disease burden. Anti-mediator intervention is not always successful in improving the quality of life of these patients. But the treatment landscape is changing. Join Drs. Cem Akin, Daniel DeAngelo, and Matthew Hamilton offer key clinical insights into this changing standard of care for ISM and discuss why allergists, hematologists, and gastroenterologists are at the vanguard of this change.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Melanie Dispenza, MD
The future therapeutic landscape for food allergy prevention is looking clearer as a drug typically used to treat hematologic malignancies has shown to prevent systemic anaphylaxis to allergens and increase patients' tolerance to peanuts. Along with this, other therapies are also in development for allergy treatment. To learn more, join Dr. Charles Turck as he dives deeper into this study and its findings with Dr. Melanie Dispenza, Assistant Professor of Medicine at Johns Hopkins University School of Medicine.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Arnaud Bourdin, MD, PhD
Since many severe asthma patients have been shown to have mucus plugs, it’s important to understand the role they plan in severe asthma. Join us as we discuss an exploratory study and the role of mucus plugging in severe asthma with Dr. Charles Turck and Professor Arnaud Bourdin. Professor Bourdin is the Head of Pulmonology at the Arnaud de Villeneuve Hospital in Montpellier, France.
TEZSPIRE is a registered trademark of Amgen Inc. and AstraZeneca.
©2024 Amgen and AstraZeneca. All rights reserved. US-83499 Last Updated 1/24
Host: Jennifer Caudle, DO
Guest: Sayantani Sindher, MD
Recently, Omalizumab was studied in patients due to the avoidance of management and guidance when it comes to treating food allergies in children and adults. According to this doctor, approximately 45 percent of patients seen in his clinic have multi-food allergies that are not being met with current treatment options. So to explain his research, Dr. Jennifer Caudle is joined by Dr. Sayantani Sinder, Clinical Associate Professor of Medicine and Pediatric Allergy and Clinical Immunology Physician at Stanford Healthcare and Stanford Medicine Children’s Health.
Host: Tauseef Ali, MD, FACG, AGAF
Host: Sabina Ali, MD
Host: Neil Nandi, MD, FACP
Host: Tina Aswani-Omprakash, MPH
A South Asian pediatric gastroenterologist discusses the epidemiology of IBD, distinct phenotypes, the latest clinical data from the mainland and diaspora, patient burden, and the importance of providing culturally competent care.
Guest: Douglas Jones, MD
A recent study was done to show the side effects of diphenhydramine for allergic reactions, and one of the main detriments was that it could impair the patient by making them tired or sleepy. Another finding was that it doesn’t work that quickly, so in turn, giving diphenhydramine in a severe allergic reaction could cause more harm than good. To learn more on what you should know before using diphenhydramine in allergic reaction situations and possible better solutions, tune in with Dr. Douglas Jones, Board-Certified Allergist and Immunologist with the Tanner Clinic in Layton, Utah.
Host: Javed Butler, MD, MBA, MPH
Guest: Jeffrey Wilson, MD
There’s a decent amount of evidence showing allergic immune responses could have connections with heart disease. But with the knowledge gaps that exist, a need for bigger cohorts is necessary to get more information and data. So to explore the link between allergic reactions from food and heart disease, Dr. Javed Butler is joined by Dr. Jeffrey Wilson, Allergist and Immunologist in the Department of Medicine’s Division of Asthma, Allergy, and Immunology at the University of Virginia.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Arnaud Bourdin, MD, PhD
It’s only been a recent discovery that mucus plugging may be present and persistent in chronic severe asthma.1 In fact, studies have shown that mucus plugs may drive some lung function deficits in severe asthma.1 Given this recent finding, Dr Charles Turck speaks with Professor Arnaud Bourdin about the clinical significance and pathogenesis of mucus plugging in severe asthma. Professor Bourdin is Head of Pulmonology at Arnaud de Villeneuve Hospital in Montpellier, France.
Reference:
- Dunican EM, Watchorn DC, Fahy JV. Ann Am Thorac Soc. 2018;15(Suppl 3):S184-S191. doi:10.1513/AnnalsATS.201807-485AW
©2024 Amgen and AstraZeneca. All rights reserved. US-86740 Last Updated 3/24
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Basil M. Kahwash, MD
Patients with asthma who have experienced challenges with exercise may find that they are hesitant to exercise again in the future, or they may think it’s not safe to pursue. However, artificial intelligence (AI) may be a useful tool in promoting exercise in asthma patients due to its ability to generate a personalized approach for the patient with a quick turnaround. Explore the benefits between AI and exercise in asthma patients with Dr. Basil Kahwash, Assistant Professor of Medicine on the Clinical Educator Track in the Department of Medicine at Vanderbilt University in Nashville, Tennessee. He also spoke about this topic at the 2023 Annual ANAC conference in his session, titled “Managing Co-Occurring Conditions: A Clinical Update.”
Guest: Michael T. Pulley, MD PhD
The chronic inflammatory demyelinating polyneuropathy (CIDP) treatment objective for disease stabilization and long-term maintenance is to get the patient to a normal functioning state with as few fluctuations and relapses as possible. Dive in with Dr. Qihua Fan, Assistant Professor in the Department of Neurology at Virginia Commonwealth University.
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA
Guest: Basil M. Kahwash, MD
Patients with asthma could benefit greatly from exercising, and over time, it could lead to better asthma control. Dive into this episode to learn more about the findings from a recent study on exercise and asthma with Dr. Mary Katherine Cheeley and Dr. Basil Kahwash, Assistant Professor of Medicine on the Clinical Educator track in the Division of Allergy, Pulmonary, and Critical Care Medicine at Vanderbilt University in Nashville, Tennessee.
Host: Raj Chovatiya, MD, PhD
Guest: Steven R. Feldman, MD, PhD
To gain a better understanding of the different treatment attributes that patients with moderate-to-severe atopic dermatitis value most, a discrete choice experiment was conducted. And now, the results are in, with itch control being the top attribute. Joining Dr. Raj Chovatiya to share this and other key findings from his research that was featured as a poster at the 2023 Fall Clinical Dermatology conference is Dr. Steven Feldman, Professor of Dermatology, Pathology, Social Sciences, and Health Policy at the Wake Forest University School of Medicine in Winston-Salem, North Carolina.
Host: Raj Chovatiya, MD, PhD
Guest: Melinda Gooderham, MSc, MD, FRCPC
Due to the evolving treatment landscape, the way we think about treating adult and elderly patients with atopic dermatitis has shifted. So what are some special considerations we need to think about when selecting a treatment option for long-term control, and how can we best involve patients in the decision-making process? Joining Dr. Raj Chovatiya to help answer these and other key questions in atopic dermatitis care is Dr. Melinda Gooderham, Medical Director for the SKiN Center for Dermatology in Peterborough, Ontario.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Kalpesh Thakkar, MD, MSCR
Cow’s milk protein allergy is the most common food allergy in infants. And overall, it’s important to know that in general, the incidence of allergy is increasing worldwide. To take a deep dive, join Dr. Charles Turck as he speaks with Dr. Kalpesh Thakkar, Pediatric Gastroenterologist at Memorial Hermann Medical Group in Sugarland, Texas.
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Guest: Natalia Castillo Almeida, MD
感染流感会增加住院和罹患严重疾病的风险，尤其对高风险患者而言。幸运的是，接种流感疫苗可以帮助个人有效应对此类情况。在本节目中，内布拉斯加州大学医学院传染病系助理教授 Natalia Castillo Almeida 医生分享了关于住院率的关键数据和流感疫苗的接种建议。
Host: Raj Chovatiya MD, PhD
Guest: Matthew Zirwas, MD
Guest: Douglas DiRuggiero, DMSc, PA-C
When managing atopic dermatitis, it’s up to the patient to determine how much therapeutic intervention they want to pursue, which underscores the importance of applying shared decision-making to practice. Joining Dr. Raj Chovatiya to share their perspectives on how we can utilize shared decision-making in atopic dermatitis care are Dr. Matthew Zirwas and Mr. Douglas DiRuggiero. Dr. Zirwas founded Bexley Dermatology Research Clinic in Columbus, Ohio where he specializes in adult eczema, and Mr. DiRuggiero is a certified physician assistant at the Skin Cancer and Cosmetic Dermatology Center in Rome, Georgia.
Host: Raj Chovatiya MD, PhD
Guest: Jennifer Soung, MD
Guest: Einjuan James Song, MD, FAAD
The atopic dermatitis treatment landscape has evolved over the past several years. To catch up on the current treatment options available and the novel therapies in development, Dr. Raj Chovatiya speaks with Drs. James Song and Jennifer Soung. Dr. Song is the Director of Clinical Research for Frontier Dermatology Partners in Everett, Washington, and Dr. Soung is the Director of Clinical Research at Southern California Dermatology in Santa Ana, California.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Keith C. Ferdinand, MD, FACC, FAHA, FASPC, FNLA
Vaccines are essential in reducing death and disability related to influenza, but unfortunately, not all patients have equal access to these life-saving resources. In fact, many barriers exist, like misinformation and lack of public awareness and education. That’s why Dr. Charles Turck speaks with Dr. Keith Ferdinand about ways we can break down barriers and improve vaccination rates among members of racial and ethnic minority communities.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: John J. Russell, MD
Guest: Darvin Scott Smith, MD
Hospitals and health systems face several economic and logistical challenges due to low rates of flu vaccination. Fortunately, there are policies, programs, and initiatives that can be implemented in health system environments and at the community level to increase flu vaccination rates. Learn more with Drs. Darvin Scott Smith and John Russell. Dr. Smith is an Infectious Disease Consultant of Public Health Works, LLC in Northern California, and Dr. Russell is a family medicine physician at Jefferson Health System in Abington, Pennsylvania.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Jonathan Silverberg, MD, PhD, MPH
Atopic dermatitis is more than a disease of the skin. It’s a complex and heterogeneous inflammatory disease mediated by multiple T-cell–driven inflammatory pathways, like the OX40 pathway, leading to chronic and persistent symptoms and significant burden.1-4 Explore the heterogeneity of atopic dermatitis and the importance of OX40 signaling in disease pathogenesis with Dr Charles Turck and Dr. Jonathan Silverberg, Professor and Director of Clinical Research and the Director of Patch Testing at George Washington University School of Medicine and Health Sciences.
References:
- Silverberg JI. Clinical Management of Atopic Dermatitis. 1st ed. 2018.
- Ratchataswan T, et al. J Allergy Clin Immunol Pract. 2021;9:1053-1065.
- Weidinger S, et al. Nat Rev Dis Primers. 2018;4:1.
- De Bruyn Carlier T, et al. J Autoimmun. 2021;120:102634.
©2023 Amgen Inc. All rights reserved. USA-451-80031 8/23
Guest: Natalia Castillo Almeida, MD
Influenza can increase the risk of hospitalization and disease severity, specifically for high-risk patients. Fortunately, the influenza vaccine can help combat this. Join Dr. Natalia Castillo Almeida, an Assistant Professor in the Division of Infectious Diseases at the University of Nebraska School of Medicine, as she shares key data on hospitalization rates and recommendations for vaccination.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Osman Mohamed Elfadil, MD
Food allergies and malabsorptive conditions limit food options for patients and can lead to malnutrition if alternative sources of nutrition aren’t found. So how might peptide-based formulations fit into our management approach for these GI-compromised patients? Joining Dr. Charles Turck to break down how peptide-based formulations work to improve GI tolerance, who might benefit from them, and the latest data from clinical trials is Dr. Osman Mohamed Elfadil, Senior Research Fellow in the Division of Endocrinology, Diabetes, Metabolism, and Nutrition at the Mayo Clinic in Rochester, Minnesota.
Guest: Jason Goldman, MD
How are standard versus adjuvanted influenza vaccines made? Here to break down the manufacturing process for these types of influenza vaccines is primary care physician Dr. Jason Goldman.
Host: Matt Birnholz, MD
Guest: Jonathan Corren, MD
As recent research demonstrates the important role that TSLP plays in asthma inflammation, Dr Matt Birnholz is joined by Dr Jonathan Corren, an Associate Clinical Professor of Medicine and Pediatrics at David Geffen School of Medicine in Los Angeles. Together, they review how TSLP acts across the spectrum of asthma inflammation, the correlation of TSLP with clinical features of asthma, and more.
©2021 Amgen. All rights reserved. US-53813 Last Updated 6/21
Host: Jennifer Caudle, DO
Guest: William Lumry, MD
Hereditary angioedema (HAE) is a rare, genetic disease that can cause recurrent, unpredictable, and potentially life-threatening attacks of swelling in the body.1 These swelling attacks can be both painful and debilitating, which is why prevention is so important.1 So what are the treatment options available that can help prevent HAE attacks? Joining Dr. Jennifer Caudle to discuss the importance of long-term prevention for HAE and the role of the treatment option TAKHZYRO (lanadelumab-flyo) is Dr. William Lumry, Clinical Professor of Internal Medicine at the University of Texas Southwestern Medical School.
IndicationTAKHZYRO® is indicated for prophylaxis to prevent attacks of hereditary angioedema (HAE) in patients ≥12 years of age.
Important Safety InformationHypersensitivity reactions have been observed. In case of a severe hypersensitivity reaction, discontinue TAKHZYRO administration and institute appropriate treatment.
Adverse Reactions: The most commonly observed adverse reactions (≥10% and higher than placebo) associated with TAKHZYRO were injection site reactions consisting mainly of pain, erythema, and bruising at the injection site; upper respiratory infection; headache; rash; myalgia; dizziness; and diarrhea. Less common adverse reactions observed included elevated levels of transaminases; one patient discontinued the trial for elevated transaminases.
Use in Specific Populations: The safety and efficacy of TAKHZYRO in …
Guest: Dr. Timothy Craig
Hereditary angioedema (HAE) is a rare genetic disease that can cause recurrent, unpredictable, and potentially life-threatening attacks of swelling in the body.2 The unpredictability of these attacks is a significant burden on patients.3 Fortunately, preventive treatments like TAKHZYRO® (lanadelumab-flyo) can help reduce the frequency and severity of HAE attacks.1 Here to share key information and data on this treatment option is Dr. Timothy Craig, Professor of Pulmonary, Allergy, and Critical Care Medicine at Pennsylvania State University.
IndicationTAKHZYRO® (lanadelumab-flyo) is indicated for prophylaxis to prevent attacks of hereditary angioedema (HAE) in patients ≥12 years of age.
Important Safety InformationHypersensitivity reactions have been observed. In case of a severe hypersensitivity reaction, discontinue TAKHZYRO administration and institute appropriate treatment.
Adverse Reactions: The most commonly observed adverse reactions (≥10% and higher than placebo) associated with TAKHZYRO were injection site reactions consisting mainly of pain, erythema, and bruising at the injection site; upper respiratory infection; headache; rash; myalgia; dizziness; and diarrhea. Less common adverse reactions observed included elevated levels of transaminases; one patient discontinued the trial for elevated transaminases.
Use in Specific Populations: The safety and efficacy of TAKHZYRO in pediatric patients <12 years of age have not been established.
No data are …
Guest: Andrew Menzies-Gow, PhD
Host: Charles Turck, PharmD, BCPS, BCCCP
Is now the time to shift the asthma management paradigm to prioritize remission as our goal? Dr. Charles Turck is joined by Professor Andrew Menzies-Gow, Director of the Lung Division and Deputy Medical Director at the Royal Brompton and Harefield Hospitals, London, UK, to discuss remission as a goal for patients with asthma. Together, they review a recently published expert consensus framework for asthma remission and discuss whether targeting remission could lead to better outcomes for patients.
At the time of recording, Professor Menzies-Gow provided services to AstraZeneca as an External Expert; Professor Menzies-Gow is now a permanent employee at AstraZeneca.
©2022 Amgen and AstraZeneca. All rights reserved. US-69837 Last Updated 12/22
Guest: John Anderson, MD
HAE is a rare, autosomal dominant genetic disease that can cause recurrent, unpredictable, and potentially life-threatening attacks of swelling in the body.1 There are approximately 6,000 patients living with HAE in the U.S. alone,2 and it’s not uncommon for patients to go undiagnosed for years after they start experiencing symptoms.1 Since early diagnosis is vital to creating a management plan that meets each patient’s individual needs,2 Dr. John Anderson is here to share key information on how we can better diagnose HAE in our patients.
References:
- Banerji A. Hereditary Angioedema: Classification, Pathogenesis, and Diagnosis. Allergy Asthma Proc. 2011;32:403–407.
- Busse PJ, Christiansen SC, Riedl MA, Banerji A, Bernstein JA, Castaldo AJ, Craig T, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Zuraw BL. US HAEA Medical Advisory Board 2020 Guidelines for the Management of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2021 Jan;9(1):132-150.
©2022 Takeda Pharmaceutical Company Limited. All rights reserved.
US-NON-7744v1.0 10/22
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Natalia Castillo Almeida, MD
Patients in urban communities often face challenges when accessing influenza vaccines. But there are ways we can help address those geographic and socioeconomic barriers. Joining Dr. Charles Turck to share key strategies for improving influenza vaccination rates in urban communities is Dr. Natalia Castillo, Assistant Professor in the Division of Infectious Diseases at University of Nebraska Medical Center.
Guest: Professor Christopher Brightling, PhD, FMedSci
Guest: Professor Bruce Levy, MD
Host: Charles Turck, PharmD, BCPS, BCCCP
For an asthma patient with active airway hyperresponsiveness, what kind of role do airway structural changes and mast cells play? And why is airway hyperresponsiveness so important? Professor Chris Brightling and Professor Bruce Levy share their clinical perspectives on airway hyperresponsiveness.
©2022 Amgen and AstraZeneca. All rights reserved. US-69836 Last Updated 10/22
Host: Christina Madison, BS, PharmD, BCACP, AAHIVP
In the midst of a potential tridemic between COVID-19, RSV, and influenza, it’s now more critical than ever to raise awareness among patients about the importance of flu vaccines. Here to provide counseling strategies for educating patients about flu vaccines is Dr. Christina Madison, Associate Professor of Pharmacy Practice at Roseman University of Health Sciences.
Host: Kevin Cleveland, PharmD, ANP
Older adults face a variety of unique challenges that increase their risk of serious influenza infections. But fortunately, vaccinations can help address these challenges. Learn more with Dr. Kevin Cleveland, Associate Professor at the Idaho State University College of Pharmacy.
Host: Jennifer Caudle, DO
Guest: Carolyn Bridges, MD
We all know that influenza vaccinations can help prevent serious infections and save lives. But how often do you consider the underrecognized benefits of these vaccines—like how influenza vaccinations can be a cost-effective solution for both patients and the entire healthcare system? Joining Dr. Jennifer Caudle to discuss these underrecognized benefits and how we can educate patients about the benefits of influenza vaccination is Dr. Carolyn Bridges, Director of Adult Immunizations at Immunize.org.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Kimberly McKeirnan, Pharm.D., BCACP
Vaccination rates are much lower in rural communities compared to other regions, which has a big impact on patients and the larger healthcare system as a whole. So what are some of the factors contributing to this disparity, and what strategies can we use to address them? Joining Dr. Charles Turck to discuss how we can increase vaccination rates in rural communities is Dr. Kimberly McKeirnan, Director of the Center for Pharmacy Practice Research at Washington State University.
Guest: Marc Riedl, MD, MS
Prior to 2008, there were limited approved treatment options for hereditary angioedema (HAE) available in the United States, but today, there are several medications approved by the U.S. Food and Drug Administration for preventing and treating HAE attacks.1 In light of the number of therapies that have been approved in recent years and continued clinical advancements in HAE research, what do we need to consider when discussing these treatment options with our patients? Here to share those key considerations and important information on the HAE treatment landscape is Dr. Marc Riedl.
References:
- Busse PJ, Christiansen SC, Riedl MA, Banerji A, Bernstein JA, Castaldo AJ, Craig T, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Zuraw BL. US HAEA Medical Advisory Board 2020 Guidelines for the Management of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2021 Jan;9(1):132-150.e3.
©2022 Takeda Pharmaceutical Company Limited. All rights reserved.
Guest: Jianxun Song, PhD
Several mRNA therapeutics are in development for cancer immunotherapy. What do we need to know about them? Dr. Jianxun (Jim) Song explores mRNA technology’s impact on antigen-specific T cells and immuno-oncology.
Host: Cem Akin, MD, PhD
Guest: Jason Gotlib, MD, MS
It could take up to 7 years for a patient to be accurately diagnosed with systemic mastocytosis. Drs. Jason Gotlib and Cem Akin take us through the guidelines, diagnostic criteria, signs and symptoms, and the most important diagnostic tests for high-suspicion patients.
Host: Peter Buch, MD, FACG, AGAF, FACP
Guest: Sarah McGill, MD, MSc
Alpha-gal allergy is a recently identified food allergy to red meat and other products made by mammals. So what more do we need to know about this new allergy, and which of our patients are at risk for anaphylaxis? To dive into this topic, Dr. Peter Buch is joined by Dr. Sarah McGill, Associate Professor of Medicine at the University of North Carolina, to discuss her recent research on alpha-gal allergy.
Host: Jennifer Caudle, DO
Guest: Ian Pavord, MA, DM, FRCP, FERS, FMedSci
Guest: Praveen Akuthota, MD
Chronic rhinosinusitis, atopic dermatitis, and eosinophilic esophagitis are three of the most common comorbidities associated with eosinophilic asthma. So how can we factor those and other comorbidities—along with a patient’s goals and preferences—into our treatment plans for eosinophilic asthma? Joining Dr. Jennifer Caudle to share their perspectives are Drs. Ian Pavord and Praveen Akuthota.
Guest: Amy Mgonja, PharmD, BCGP, CPPS
Training pharmacists to administer vaccines can reduce barriers to immunizations and improve patient care. Here to discuss the ApHA Pharmacy-Based Immunization Delivery Program and the important role that pharmacists play in educating and vaccinating patients is Dr. Amy Mgonja, clinical consultant pharmacist at Dawa Rx Consulting.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Nick Kusnezov, MD
Can you balance locum tenens with a full-time career? To answer that question, Dr. Charles Turck is joined by board-certified orthopedic surgeon, Dr. Nicholas Kusnezov, to walk us through his journey from joining the military to locum tenens.
The treatment landscape for eosinophilic asthma is a rapidly changing field, with new therapies arriving on a regular basis. One of the newer therapeutic approaches available is biologics. But how do they work to treat eosinophilic asthma? And which of our patients should be prescribed biologics and when? Tune in to hear Dr. Ian Pavord answer those and other key questions about the role of biologics in the eosinophilic asthma treatment landscape with Dr. Charles Turck.
Eosinophils are part of a complex set of allergic mechanisms in eosinophilic asthma. But eosinophils are far from the only component or driver of disease. Here to share key insights on the role of eosinophils along with genetic and environmental factors in the pathophysiology of eosinophilic asthma is pulmonary and critical care physician Dr. Praveen Akuthota.
Host: Peter Buch, MD, FACG, AGAF, FACP
Guest: Frances Onyimba, MD
Over the last two decades, up to 20 percent of the population in industrialized nations have reported an abnormal physical response to food ingestion, also known as an adverse reaction to food. So what key information do we need to know about food allergies and intolerances amid this recent rise around the world? To find out, Dr. Peter Buch is joined by Dr. Frances Onyimba, Assistant Professor of Medicine at the University of Maryland School of Medicine. Together, they’ll discuss how we can better identify and diagnose food allergies and intolerances.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Trevor Cabrera, MD
What’s it like becoming a locum tenens physician right out of residency? Dr. Charles Turck joins Dr. Trevor Cabrera, a Board-Certified pediatrician who trained in Houston, Texas, to share his firsthand experience and offer advice for residents.
Host: Jennifer Caudle, DO
Guest: Maurice G. Sholas, MD, PhD
After years of serving the New Orleans community, one physician decided to pursue locum tenens work. Dr. Jennifer Caudle joins Dr. Maurice Sholas, a pediatric physical rehabilitation physician, to share his experiences with locum tenens and in New Orleans.
Host: Paul P. Doghramji, MD, FAAFP
Guest: Samantha Conroy, MD
Locum tenens can improve quality of care around the globe—especially in remote and underserved communities. To share how, Dr. Paul Doghramji joins Dr. Samantha Conroy, a family practice obstetrician to share her experiences working as a locum tenens obstetrician in underserved communities.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Trevor Cabrera, MD
What’s it like becoming a locum tenens physician right out of residency? Dr. Charles Turck joins Dr. Trevor Cabrera, a Board-Certified pediatrician who trained in Houston, Texas, to share his firsthand experience and offer advice for residents.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Heather Moday, MD
When we say the words behavior, diet, habits, and environment, chances are you don't think of the body's immune system. But based on recent research, all of those factors play a role in influencing immune function. So how can we keep them in mind and boost our immunity in the face of prevalent diseases, including COVID-19? Find out with Dr. Charles Turck as he speaks with Dr. Heather Moday, author of The Immunotype Breakthrough: Your Personalized Plan to Balance Your Immune System, Optimize Health, and Build Lifelong Resilience.
Host: John J. Russell, MD
Guest: Joseph E. Bavaria, MD
Featuring a wide range of disciplines and a new approach to comprehensive care, what do we need to know about the Aorta Center at Penn Medicine? Dr. John Russell is joined by Dr. Joseph E. Bavaria to dive into this aortic program and discuss a new approach to comprehensive care.
Host: Muhammad Adrish MD, MBA, FCCP, FCCM
Guest: Navitha Ramesh, MD, FCCP
Inhalers are one of the most common methods of delivery for the treatment of COPD, but is it the best option for all of our patients? Associate Professor of Pulmonary Critical Care at Baylor College of Medicine, Dr. Muhammad Adrish, reviews LAMA use for COPD patients with Dr. Navitha Ramesh, Assistant Professor at Drexel University College of Medicine.
This episode is produced in partnership with the American College of CHEST Physicians and is sponsored by Viatris Inc.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Kathryn Gallagher, MS, RN, BSN
Guest: Kate Newcomb-DeSanto, MSN, RN, MSW
What does Penn Medicine’s newly-opened patient room facility have to offer? Dr. Charles Turck is joined by Penn Medicine Clinical Advisors Kathy Gallagher and Kate Newcomb-DeSanto to discuss the new pavilion and how it's revolutionizing patient care.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Sandy Marks
Guest: Kim Horvath, JD
Guest: Kyle Thomson, JD
With telehealth services expanding during the COVID-19 pandemic, has our access to them changed? To better understand this, Dr. Charles Turck meets with Sandy Marks, Kim Horvath, and Kyle Thomson from the AMA to explore what’s been done to provide Medicare coverage during a public health emergency and what’s on the horizon for telehealth access.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Emily Carroll, JD, MSW
The No Surprises Act aims to protect consumers from surprise medical bills. But how exactly does it go about doing that, and what’s the current status of its implementation? Joining Dr. Charles Turck to share progress and challenges associated with the No Surprises Act is Ms. Emily Carroll, a senior legislative attorney for the American Medical Association's Advocacy Resource Center.
Host: Jennifer Caudle, DO
Guest: Sarah Ali, MD
From working in a big city to taking on an assignment in a small mountain village, Dr. Sarah Ali from the Ventura County Medical Center joins Dr. Jennifer Caudle to talk about her adventures abroad with locum tenens and share key lessons she learned along the way.
Guest: Vivian Shi, MD, FAAD
Atopic dermatitis is one of the most common chronic inflammatory skin diseases in America, especially among African American and Asian American patients. However, several factors contribute to the misdiagnosis and underdiagnosis of atopic dermatitis among these patients, which is why Dr. Vivian Shi is here to shed light on those factors as well as the key signs and symptoms of atopic dermatitis in patients with skin of color.
VERSION 1.0 | NOVEMBER 2021 | ABBV-US-00686-MC
Guest: Vivian Shi, MD, FAAD
Atopic dermatitis affects patients’ lives in a way that goes beyond just visible symptoms. In fact, many patients with atopic dermatitis also suffer from anxiety, depression, and attention deficit hyperactivity disorder. That’s why Dr. Vivian Shi is here to review available tools that can help us assess the severity of the visible and invisible impacts of atopic dermatitis.
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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Hassan Bencheqroun, MD
Evaluating the need for therapy escalation can be challenging. So joining Dr. Charles Turck to help us understand how to escalate treatment for patients with chronic obstructive pulmonary disease is Dr. Hassan Bencheqroun, Assistant Professor of Medicine at the University of California Riverside School of Medicine.
This is a non-promotional, non-CME disease state disease education podcast series brought to you by American College of CHEST Physicians in collaboration with and paid for by GSK.
Guest: Phil Lieberman, MD
Host: Jennifer Caudle, DO
Are you familiar with the role of serum tryptase testing in diagnosing idiopathic anaphylaxis and mastocytosis? What role does serum tryptase play in the ongoing management of patients who have anaphylactic reactions to insect venom, and are there different considerations when a patient has a known trigger? Expert faculty Dr. Phil Lieberman shares his insights on serum tryptase testing in clinical practice and its importance in assessing mast cell disorders and anaphylaxis. This moderated discussion is enhanced with animation, key takeaways, and support slides to provide an engaging learning experience.
Serum tryptase plays an important diagnostic role in the setting of mast cell activation resulting from a variety of causes, including mastocytosis and anaphylaxis. Emergency medicine specialists, allergists, and primary care providers serve as the first-line responders to patients experiencing the effects of mast cell activation. The measurement of tryptase levels helps confirm diagnoses and inform management decisions for these life-threatening disorders. To help physicians provide optimal evaluation and management, it is essential that they be knowledgeable regarding the appropriate use of tryptase testing in these clinical settings. This education enables multidisciplinary clinicians to identify patients at risk of mast cell activation due to a variety of causes and employ …
Guest: Randy Cron, MD, PhD
Dr. Randy Cron, Professor of Pediatrics and Medicine at the University of Alabama at Birmingham and the Director of the Division of Pediatric Rheumatology at Children’s of Alabama, shares highlights from his session on “Rheumatology Complications of Emerging Viral Infections and SARS-CoV-2” from the 2021 American College of Rheumatology Convergence.
Guest: Cem Akin, MD, PhD
Host: Jennifer Caudle, DO
What is the risk of anaphylaxis following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19)? Are you familiar with the role of serum tryptase testing in patients with a suspected anaphylactic reaction? Expert faculty, Dr. Cem Akin, discusses serum tryptase testing and its importance in assessing anaphylaxis in response to COVID-19 vaccination. This moderated discussion is enhanced with animation, key takeaways, and support slides to provide an engaging learning experience.
Serum tryptase plays an important diagnostic role in the setting of mast cell activation resulting from a variety of causes, including mastocytosis and SARS-CoV-2 vaccination. Emergency medicine specialists, allergists, and primary care providers serve as the first-line responders to patients experiencing the effects of mast cell activation. The measurement of tryptase levels helps confirm diagnoses and inform management decisions for these life-threatening disorders. This education enables multidisciplinary clinicians to identify patients at risk of mast cell activation due to a variety of causes and employ appropriate use of tryptase testing across acute and follow-up care settings.
Host: Paul P. Doghramji, MD, FAAFP
Guest: Mojgan Saber, MD
Can Locum Tenens be an option for healthcare professionals just completing their residency? Dr. Paul Doghramji is joined by Dr. Mojgan Saber to share her own experience as well as tips and tricks for residents looking at Locum Tenens right after residency.
Host: Charles P. Vega, MD
Guest: Robert O. Roswell, MD, FACC, FACP
Diversifying our physician workforce so that it is more racially, ethnically, and geographically balanced can ultimately have a positive impact on community health. Join us as two experts discuss how pipeline programs reaching children as early as elementary school can help ensure workplace diversity. Also find out how clinicians can be advocates for their patients by helping to disentangle them from structural inequities and working towards policy changes. There’s a lot than can be done to provide more balanced care, but we need to look beyond simple fixes to the root causes of the issues. So find your bandwidth – that’s what you can do today – and discover why it’s so important to move upstream to solve the problems manifesting downstream.
Host: Charles P. Vega, MD
Guest: Candice Taylor Lucas, MD, MPH, FAAP
What is cultural humility, and how can it be incorporated into clinical practice? How does your patient's culture impact their health behaviors, and why does your culture matter?
Listen in as two leading experts navigate concerns surrounding cultural humility and emphasize the importance of empathy, awareness, and advocacy. Discover ways to integrate small but important changes into your clinical practice to help bridge communication gaps and enable your patients to thrive.
Host: Charles P. Vega, MD
Guest: Sateria Venable
Regional healthcare disparities are biases that are based on where people live. Are your patients’ treatment options being impacted and limited by their geographical location? Join us as our two experts discuss how to support broader policy issues and highlight the importance of diagnostic algorithms that have been developed with diverse input. These steps may be of value in your clinical practice to ensure all patients have equal access to care regardless of their epidemiologic, socioeconomic, or insurance circumstances.
Host: Charles P. Vega, MD
Guest: Lionel Phillips, MBA
Learn why diversity in clinical trials is so important to community health. Two experts discuss the key role that trusted messengers play in enrollment, why it is critical to break the cycle of medical mistrust, and the downstream effect of a lack of diversity in clinical trials.
Host: Jennifer Caudle, DO
Guest: Stephen Hanauer, MD
Even though biosimilars serve as a much-needed treatment option for patients in several fields of medicine, gastroenterologists have been reluctant to adopt them. Joining Dr. Jennifer Caudle to explore why this might be and the evolving role of biosimilars in anti-inflammatory care for GI patients is Dr. Stephen Hanauer, Professor of Medicine at the Northwestern University Feinberg School of Medicine in Chicago, Illinois.
USA-CBU-81030
Guest: Brian Hill, MD, PhD
Dr. Brian T. Hill, a physician in the Department of Hematology and Medical Oncology at Cleveland Clinic, explores some of the most recent—and ongoing—impacts of the COVID-19 pandemic on treatment decision-making for patients with chronic lymphocytic leukemia.
Host: Matt Birnholz, MD
Guest: Jonathan Corren, MD
As recent research demonstrates the important role that TSLP plays in asthma inflammation, Dr Matt Birnholz is joined by Dr Jonathan Corren, an Associate Clinical Professor of Medicine and Pediatrics at David Geffen School of Medicine in Los Angeles. Together, they review how TSLP acts across the spectrum of asthma inflammation, the correlation of TSLP with clinical features of asthma, and more.
©2021 Amgen. All rights reserved. US-53813 Last Updated 6/21
Host: Tracey Evans, MD
Guest: Raja Mudad, MD
TECENTRIQ® (atezolizumab), in combination with carboplatin and etoposide, is a first-line treatment option for adult patients with extensive-stage small cell lung cancer. What does this treatment path look like in clinical practice? Dr. Tracey Evans is joined by medical oncologist Dr. Raja Mudad to walk us through an example patient case that gives us a better sense of key diagnostic factors, treatment approach, and patient management.
This program is intended for US Physicians.
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Host: Tracey Evans, MD
Guest: Raja Mudad, MD
For thirty years, there were limited therapeutic advancements leading to FDA approvals in extensive-stage small cell lung cancer (ES-SCLC). However, this all changed with the IMpower133 trial, which led to the emergence of immunotherapy as a first line treatment option in ES-SCLC. Joining Dr. Tracey Evans is medical oncologist Dr. Raja Mudad to discuss the IMpower133 trial and the reasons to consider TECENTRIQ® (atezolizumab), the first immunotherapy combination for patients with ES-SCLC.
This program is intended for US Physicians.
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Host: Jennifer Caudle, DO
Guest: Michael Wechsler, MD
In addition to understanding the definitions of severe asthma and uncontrolled asthma, it’s important for clinicians to be aware of the overall burden that severe asthma and uncontrolled asthma can impose on a patient’s life. So to help us better understand the severe asthma spectrum, Dr Jennifer Caudle is joined by Dr Michael Wechsler, Director of the Cohen Family Asthma Institute at National Jewish Health in Denver, Colorado.
©2021 Amgen. All rights reserved. US-53805 Last Updated 6/21
Host: Jennifer Caudle, DO
Guest: Tracey Evans, MD
Small cell lung cancer (SCLC) is a highly aggressive, lethal, and widely metastatic lung cancer. While therapeutic progress in SCLC has been limited over the years, immunotherapy has made some meaningful advancements in the treatment landscape. Joining Dr. Jennifer Caudle to discuss key diagnostic and therapeutic considerations such as TECENTRIQ® (atezolizumab) for 1L ES-SCLC, is Dr. Tracey Evans, Director of Thoracic Oncology Research at Lankenau Institute for Medical Research and Co-Director of the Thoracic Oncology Program at Main Line Health.
This program is intended for US Physicians.
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Guest: Carlos del Rio, MD
Guest: Angela Rasmussen, PhD
With cases of COVID-19 surpassing 51 million worldwide, the rush to develop a vaccine capable of slowing the pandemic and lessening the morbidity and mortality of SARS-CoV-2 is underway. Several COVID-19 vaccines are now being studied in phase 3 trials, and clinicians would benefit from a review of these ongoing efforts, particularly the status of vaccines close to approval. This podcast will provide clinicians a review of up-to-date safety and efficacy information on vaccine candidates in late-stage development, and steps to prioritize patients who would benefit most from vaccination once available.
Host: Hector O. Chapa, MD, FACOG
Guest: Cameron Ayala
Hundreds of millions of people worldwide suffer from lymphedema and lymphatic diseases. Joining us to provide a personal perspective on this condition is Cameron Ayala, a former reality TV persona, compression specialist, and lymphedema patient who will be sharing his experience with Dr. Hector Chapa.
Host: Jennifer Caudle, DO
Guest: Anjali Patwardhan, MD
In pediatric patients, can the influenza and pneumococcal vaccines impact the COVID-19 disease course? Dr. Jennifer Caudle joins Dr. Anjali Patwardhan, a pediatric rheumatologist at the University of Missouri Healthcare, to discuss COVID-19 in pediatric patients who’ve been vaccinated for influenza and pneumococcal.
Published March 16, 2021
Host: Carol Wysham, MD
Guest: Alexis McKee, MD
Patient care has evolved amid the COVID-19 pandemic, causing unexpected challenges in managing diseases such as diabetes. Dr. Carol Wysham joins Dr. Alexis McKee, a practicing endocrinologist and an assistant professor of medicine at Washington School of Medicine in St. Louis, Missouri, to discuss how patients have been overcoming challenges in managing diabetes during the pandemic.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Drew Weissman, MD, PhD
Dr. Drew Weissman, Professor of Medicine at Penn Medicine joins Dr. Turck to discuss his new COVID-19 vaccine technology and how RNA and mRNA are being used to provoke an immune response in order to combat the COVID-19 pandemic.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Frank Scott
Dr. Charles Turck is joined by Dr. Frank Scott from the University of Colorado School of Medicine to share some highlights from his session, “Challenges and New Approaches to Managing IBD in the COVID-19 Era,” at Crohn’s & Colitis Congress 2021.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Maria M. Oliva-Hemker, MD
With current treatment approaches in mind, how do immunomodulators fit into the therapeutic landscape for inflammatory bowel disorders, or IBD? In preparation for the 2021 Crohn’s & Colitis Congress, Dr. Charles Turck speaks with Dr. Maria Oliva-Hemker from Johns Hopkins University School of Medicine about her presentation at the event.
Guest: John J. Russell, MD
With so many COVID-19 vaccines in development, new medical ethical questions have been brought to the forefront of the healthcare field. With that in mind, Dr. John Russell takes us through the history of ethics and vaccinations throughout the world.
Published January 4, 2021
Host: John J. Russell, MD
Guest: William G. Callahan, DO
The COVID-19 pandemic has compelled many to stay home, but for those venturing out, how can we encourage them to stay safe? Dr. Bill Callahan, a family physician at Abington Jefferson Health and outdoorsman, sits down with Dr. John Russell to discuss how to stay safe during this winter pandemic.
Host: Jacob Sands, MD
Guest: Nabil F. Saba, MD
Emerging research on head and neck cancer has moved away from HPV-negative diseases upon the discovery of HPV-positive diseases, specifically HPV-positive oropharynx cancer. What do we know about managing and treating this disease? Dr. Nabile Saba dives into treatment considerations, specifically immunotherapy, for patients with HPV-positive head and neck cancer.
Host: Linda Bernstein, Pharm.D.
Asthma remains a significant global health problem, and more than 25 million Americans suffer from it. How have the National Asthma Education and Prevention Program’s guidelines changed to help manage this chronic condition? In this episode of The Drug Report, Dr. Linda Bernstein reviews new guidelines on the management of asthma in adolescents and adults.
Published December 10, 2020
Host: Megan Carreon, MHA, RRT
Guest: Amy Levinger, MSN, FNP-C
Guest: Timothy Aksamit, MD
There are numerous factors that contribute to an overall wellness of patients with of NTM refractory MAC lung disease. Listen in as Megan Carreon, Assistant Professor with the Division of Respiratory Care at UT Health San Antonio, Texas, sits down with pulmonary nurse practitioner Amy Levinger from NYU Langone Health and Dr. Tim Aksamit, Associate Professor of Pulmonary and Critical Care Medicine at Mayo Clinic.
For more information and to access clinician & patient tools about NTM and MAC Lung Disease, click here to visit the CHEST Foundation NTM webpage.
This program is produced in partnership with the American College of CHEST Physicians, and is sponsored by Insmed Incorporated.
Guest: John J. Russell, MD
Could immunization techniques of the past help us in our current hunt for a COVID-19 vaccine? To find out, Dr. John Russell reviews the history of immunizations going all the way back to the 1100s.
Published May 29, 2020
Host: Linda Bernstein, Pharm.D.
Allergic reactions to peanut are unpredictable in occurrence and in how they present, with some individuals experiencing severe reactions from even trace amounts. Fortunately, there’s now an FDA-approved treatment option available that—when used in conjunction with peanut avoidance—can help reduce the risk of these allergic reactions in children with peanut allergy, as pharmacist Dr. Linda Bernstein explains.
Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR
Please note: This activity is no longer available for continuing education credit.
Tune in as a multidisciplinary panel discusses a clinician's question about the appropriateness of combining two biologics in a very young child with several atopic diseases.
Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR
Please note: This activity is no longer available for continuing education credit.
Infants have the highest incidence of atopic dermatitis in the US but the fewest treatment options. This is a case a doctor submitted about a baby who is refractory to multiple oral and topical treatments. A multidisciplinary panel discusses how they would approach the baby's treatment, emerging options for this vulnerable patient population, and if anything can be done now to prevent progression of the atopic march later.
Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR
Please note: This activity is no longer available for continuing education credit.
A multidisiplinary panel is presented with a highly allergic, extremely refractory patient with atopic dermatitis. Her dermatologist wants to take the next step and start her on a biologic, but she's worried about the patient's occular history and dupilumab's conjunctivitis risk. Find out what the experts have to say about this doctor's dilemma.
Host: Joseph K. Han, MD
Please note: This activity is no longer available for continuing education credit.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with significant morbidity and negatively impacts quality of life. The good news is that biologic therapies targeting type 2 inflammatory pathways provide additional treatment options for CRSwNP. However, clinicians not only need to accurately diagnose nasal polyps in patients but also recognize the role of the underlying pathology to incorporate biologic agents into treatment regimens when appropriate, as Dr. Joseph K. Han explains.
Host: Nicola A. Hanania, MD, MS, FCCP
Guest: Neil J. Freedman, MD
Coming from the 2019 annual CHEST conference in New Orleans, Dr. Nicola Hanania joins Dr. Neil Freedman to discuss the advances in the diagnosis and treatment of COPD as well as the updated GOLD guidelines that were covered at the conference.
Host: Sandhya Khurana, MD, FCCP
Guest: Monica Kraft, MD, FCCP
Recorded live at the 2019 annual CHEST conference in New Orleans, Dr. Monica Kraft joins Dr. Sandhya Khurana to talk about how the new available biologics are going to fit into the severe asthma treatment landscape along with other highlights from the conference.
Find out what Dr. Khurana and Dr. Kraft think you should do right now to improve treatment of severe asthma! This episode is supported in part by an unrestricted/independent medical educational grants from the following: Genentech, GlaxoSmithKline, and Novartis Pharmaceuticals Corporation.
Host: Reynold A. Panettieri, Jr., MD
Guest: Michael Wechsler, MD
Guest: Jonathan Corren, MD
Please note: This activity is no longer available for continuing education credit.
The management of severe asthma has changed drastically after the introduction of biologics. However, their introduction comes with many questions, such as, When should they be used and in whom? This Care Team ForumSM brings pulmonologists and an allergist/immunologist in dialogue with a patient about the immunologic underpinning of asthma pathology and how it relates to identifying patients appropriate for step-up care with biologics.
Host: Peter A. Lio, MD
Guest: Eric Simpson, MD, MCR
Guest: Mark Boguniewicz, MD
Please note: This activity is no longer available for continuing education credit.
“I begged my doctor for something else – there had to be something else,” Pam.
For over 50 years, Pam suffered with uncontrolled moderate-to-severe atopic dermatitis (AD). She experienced the evolution of treatment strategies over the course of the several decades, trying everything from topicals to off-label targeted systemic agents. She was willing to try anything to make the unbearable itch go away. In this roundtable discussion, we brought Pam and her dermatologist to discuss AD with a multidisciplinary physician panel. Together they weigh in on experimental and newly approved therapies, management strategies, impact on quality-of-life, and shared decision-making techniques, all supplemented by Pam’s unfiltered, down-to-earth reality check of what life with AD and all these drugs really feels like.
Host: Jennifer Caudle, DO
Guest: Barbara Pahud, MD
More patients are receiving conflicting information about vaccines, and after the rise of preventable outbreaks in 2019, Dr. Barbara Pahud joins Dr. Jennifer Caudle to debunk the most common myths surrounding vaccines and to share how we can better educate our patients.
Host: Matt Birnholz, MD
Guest: Claudette Poole, MD
There’s been a rising number of parents who delay or refuse vaccines for their child, causing the World Health Organization to list vaccine hesitancy as one of the top 10 threats to global health. Joining Dr. Matt Birnholz to discuss how and why we got to this point along with tips physicians can use to better inform parents about vaccinating their child is Dr. Claudette Poole.
Host: John J. Russell, MD
Guest: Meredith Wadman, BM, BCh, M.S.
Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses.
In June 1962, a young biologist in Philadelphia, using human tissue samples sent from Sweden, produced a line of cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a massive German measles epidemic, the vaccine that would one day wipe out homegrown rubella was introduced. This vaccine has since protected more than 150 million people in the United States, and its development method has also led to other vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles, and adenovirus.
Host Dr. John Russell chats with Meredith Wadman, author of The Vaccine Race: Science, Politics, and the Human Costs of Defeating Disease, about the story of both the science of this urgent race and the political and ethical controversies that nearly ended it prematurely.
Anti-TNF Treatment for Extraintestinal Manifestations of Inflammatory Bowel Disease in the Swiss IBD Cohort Study.
Vavricka SR1, Gubler M, Gantenbein C, Spoerri M, Froehlich F, Seibold F, Protic M, Michetti P, Straumann A, Fournier N, Juillerat P, Biedermann L, Zeitz J, Misselwitz B, Scharl M, Heinrich H, Manser CN, Safroneeva E, Raja Ali RA, Rogler G, Schoepfer AM, Greuter T; Swiss IBD Cohort Study Group. BACKGROUND: Extraintestinal manifestations (EIMs) in patients with inflammatory bowel disease (IBD) are frequently observed. Little is known about the efficacy of anti-tumor necrosis factor (TNF) in EIM management. We assessed the effect of 3 anti-TNF agents (infliximab, adalimumab, and certolizumab pegol) on EIM evolution.
METHODS: Data on 1249 patients from the Swiss IBD Cohort Study (SIBDCS) were analyzed. All EIMs were diagnosed by relevant specialists. Response was classified into improvement, stable disease, and clinical worsening based on the physician's interpretation.
RESULTS: Of the 366 patients with at least 1 EIM, 213 (58.2%) were ever treated with an anti-TNF. A total of 299 treatments were started for 355 EIMs. Patients with EIM were significantly more often treated with anti-TNF compared with those without EIM (58.2% versus 21.0%, P < 0.001). …
Host: John J. Russell, MD
Do pets help prevent allergies? Does the 5-second rule actually exist? And is dirt really good for a child’s immune system?
Host Dr. John Russell talks with Jack Gilbert, Ph.D., Professor of Surgery at the University of Chicago and Director of the Microbiome Institute. Dr. Gilbert is author of the book Dirt is Good,answering questions about the potential benefits of exposure to germs and bacteria. He and Dr. Russell sift through common misconceptions about microbiomes to better understand their actual risks and benefits for the body's immune system, explaining its role in disease and health.
Host: Brian P. McDonough, MD, FAAFP
Allergies occur when your immune system mistakes a normally harmless allergen for a dangerous invader and moves to destroy it, producing an allergic reaction. What exactly causes this response, and what are the best treatments to combat it?
Host Brian McDonough chats with Dr. Avery August, Professor of Microbiology and Immunology at Cornell’s College of Veterinary Medicine, about his research regarding how allergens affect the immune system.
Host: Matt Birnholz, MD
Guest: Robert McNally, MD
From the Villanova Health Summit's Speaker Event, host Dr. Matt Birnholz speaks with guest Dr. Robert McNally, President, and CEO of GeoVax, Inc. They discuss the challenges that biotech companies face when bringing vaccines through clinical trials, and the long-term project being conducted by his colleagues to deliver an HIV vaccine to market.
Host: Lea Ann Chen, MD
Guest: Hans Herfarth, MD
Recorded on location at the Crohn’s & Colitis Foundation’s Annual Meeting in Orlando, host Dr. Lea Ann Chen, Assistant Professor of Medicine at New York University, discusses goals of therapy in IBD with Dr. Hans Herfarth, Professor of Medicine at University of North Carolina School of Medicine.
Host: Kathy King, RDN
It's estimated that 4 - 8% of the U.S. population has at least one food allergy, and the incidence rate appears to be growing. How do we explain this harmful trend in public health, and what can clinicians and patients do to help mitigate the risk of developing food allergies?
Host Kathy King is joined by Debra Indorato, nutrition advisor for Kids With Allergies, which is a division of the Asthma and Allergy Foundation of America. The two discuss the latest understandings and dietetic approaches to food allergies, sensitivities, and intolerances.
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Eugenia Gianos. Dr. Gianos is an assistant professor in the Department of Medicine and co-clinical director of the Center for the Prevention of Cardiovascular Disease at the NYU School of Medicine.
Dr. Gianos discusses the effectiveness, potential side effects, and patient outcomes with PCSK9 antibodies for management of dyslipidemia.
Host: Matt Birnholz, MD
The simple act of going out to eat can be a tricky proposition for people dealing with gluten intolerance or sensitivity issues. A new portable device is aiming to help people with this problem by allowing them to test food’s gluten content and help find foods that they are able to eat.
Host Dr. Matt Birnholz talks with guest Carla Borsoi, Vice President of Marketing at 6Sensor Labs, about how this device will assist people living with gluten intolerance or sensitivity issues.
Host: Brian P. McDonough, MD, FAAFP
For most people, the home is a refuge and an oasis, a place to feel safe. But few ever wonder whether their homes and the everyday household items they use to clean and maintain them could be detrimental to their health.
Joining Dr. Brian McDonough to discuss the unsettling health risks behind common household items, and what consumers should keep an eye on, is Andre LaCroix, Vice President of Easy Breathe, Inc.
[Read the Article]
Air pollution is associated with chronic respiratory health problems in children. A new study examined whether decreases in air pollution levels are associated with significant reductions in respiratory symptoms in children.
Researchers from the University of Southern California followed over 4,600 children in eight Southern California communities across three different time periods from 1993-2012. In addition to monitoring air quality, they also looked at children with and without asthma, and whether they reported respiratory symptoms like bronchitis, congestion, phlegm production, or a daily cough for three months in a row, during the previous year.
Along with significant improvements in air pollution levels, the authors found a decrease in reported respiratory symptoms in children both with and without asthma. Respiratory symptoms decreased by 32 percent in children with asthma and 21 percent in children without.
[Watch more videos of The JAMA Report]
[Read the Article]
Recent outbreaks of vaccine-preventable diseases in the United States have prompted clinicians, public health officials and the public to pay closer attention to the growing phenomenon of vaccine refusal. A new study looks at the role of vaccine refusal and the risk of measles and pertussis. In recent years, a substantial proportion of US measles cases occurred in people who were intentionally unvaccinated. Vaccine refusal was also found to be associated with an increased risk of pertussis in some populations.
[Watch more videos of The JAMA Report]
Host: Matt Birnholz, MD
Inflammation plays a pivotal role in the development and persistence of many chronic diseases, but only recently has the human microbiome been linked as something more central to inflammatory processes than a passive reservoir. What roles do the gut, microbiome, and gut-brain axis play in chronic disease development, as well as prevention?
From the floors of the A4M Conference in Las Vegas, Dr. Matt Birnholz speaks with James LaValle, founder and CEO of Metabolic Code Enterprises, Inc and a nationally recognized clinical pharmacist, author, and board certified clinical nutritionist. The two discuss expanded understandings of the microbiome's influence on human health and disease, both in the U.S. and worldwide.
Over the past decade, Food Protein Enterocolitis, or FPIES, has emerged as the most actively studied non–IgE-mediated gastrointestinal food allergy because of its acute onset, severity of symptoms, and distinctive clinical features. Yet as a rare allergic disorder of infancy and young childhood, it is often misinterpreted and misdiagnosed in clinical practice, leading to difficult treatment paths for patients and their families. Joining Dr. Renee Matthews to present a case history from the vantage point of a patient's mother, including challenges faced in reaching the correct diagnosis and starting effective treatment regimens, is Jennifer Kandt.
Host: Brian P. McDonough, MD, FAAFP
As an unforgivingly cold, frigid winter in America has led to the explosive release of tree pollens over a short period this spring, seasonal allergies have returned with a vengeance. Says, Dr Mitchell Gaynor, clinical assistant professor of medicine at Weill Cornell Medical College in New York City, this could make for one of the worst allergy seasons of all time. How can primary care providers ready themselves on the frontlines of this mass allergy assault? Dr. Brian McDonough and Dr. Gaynor discuss strategies to keep clinicians on top of this emerging threat, including new understandings of eco-genetic mechanisms of allergic disease.
Host: Brian P. McDonough, MD, FAAFP
Irritable Bowel Syndrome affects an estimated one out of ten people in the US, yet the causes for this disease are multivariate and often unknown from case to case, creating a reputation in practice as a "waste basket diagnosis." Dr. Michael Stierstorfer, Clinical Associate Professor of Dermatology at the University of Pennsylvania School of Medicine and founder of East Penn Dermatology, has been a pioneer in helping clinicians better understand one potential cause of IBS. His own experience as IBS patient led to the remarkable discovery of an allergic contact enteritits underscoring his disease, which has led to new diagnostic and treatment algorithms for IBS patients nationwide. Dr. Stierstorfer joins Dr. Brian McDonough to discuss this unexpected path toward discovery and subsequent career specialization.
Host: Brian P. McDonough, MD, FAAFP
Dr. Brian McDonough welcomes Tanya Winders, President and Chief Executive Officer for the Allergy and Asthma Network, the leading patient advocacy organization dedicated to ending needless suffering and death due to asthma, allergies, and related conditions. They discuss ways of addressing healthcare access challenges for asthma and allergy patients, from socioeconomic support structures to education models to special risk situations like enterovirus outbreaks.
Host: Brian P. McDonough, MD, FAAFP
Allergic complaints in primary care settings are sometimes more than they appear, raising the importance of good diagnostic criteria for other underlying problems. Joining Dr. Brian McDonough for an in-depth discussion of allergy in the general and specialized practice levels is Dr. Will Sheppard, a board certified Otolaryngologist/ Head and Neck Surgeon and a Fellow of the American Academy of Otolaryngic Allergy. His practice includes medical and surgical management of ear, nose, and throat disorders of pediatric and adult patients.
Host: Matt Birnholz, MD
Current Guidelines conclude that enlisting greater numbers of primary care clinicians to improve access to quality care will help people gain control of their asthma and allergy, thusly improving patients' quality of life. This activity was developed based on the current recommendations and guidelines issued by national organizations, and is designated to close gaps in knowledge, awareness, attitudes, and decision-making patterns related to the treatment and referral of patients with asthma and allergy.
Presenting this Prova Education Live Event is Dr. Michael Wechsler, Assistant Professor of Medicine at Harvard Medical School and Associate Director of the Brigham and Women's Hospital Asthma Research Center.
This is Part 2 of a lecture in two parts.
Part 1 >>
To view the complete video recording of this and other Prova Education Live Events, visit http://www.provaeducation.com
And to download a copy of the American Lung Association's "Asthma Action Plan" referenced in this program, visit http://www.lungusa.org/lung-disease/asthma/living-with-asthma/take-control-of-your-asthma/asthma-action-plan.html
Host: Matt Birnholz, MD
Current Guidelines conclude that enlisting greater numbers of primary care clinicians to improve access to quality care will help people gain control of their asthma and allergy, thusly improving patients' quality of life. This activity was developed based on the current recommendations and guidelines issued by national organizations, and is designated to close gaps in knowledge, awareness, attitudes, and decision-making patterns related to the treatment and referral of patients with asthma and allergy.
Presenting this Prova Education Live Event is Dr. Michael Wechsler, Assistant Professor of Medicine at Harvard Medical School and Associate Director of the Brigham and Women's Hospital Asthma Research Center.
This is Part 1 of a lecture in two parts.
Part 2 >>
To view the complete video recording of this and other Prova Education Live Events, visit http://www.provaeducation.com
And to download a copy of the American Lung Association's "Asthma Action Plan" referenced in this program, visit http://www.lungusa.org/lung-disease/asthma/living-with-asthma/take-control-of-your-asthma/asthma-action-plan.html
Guest: William Goggins, MD
Host: Aaron Carroll, MD
Some patients needing kidney transplants have to wait much longer than others because of their sensitization to human leukocyte antigen (HLA). How are new desensitization protocols opening the door to transplantation for these patients who were previously ineligible? Host Dr. Aaron Carroll talks to Dr. William Goggins, kidney transplant surgical director at Indiana University Health.
Host: Matt Birnholz, MD
This year's meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI), held in San Francisco over March 18th through the 22nd, attracted over 7,000 participants from around the world, including clinicians, academics, allied health professionals, and others interested in allergic and immunologic disease. The conference highlighted recent advances in allergy and immunology research, with presentations also focusing on other developments in allergy, asthma, and immunologic diseases.
Host: Matt Birnholz, MD
Tune in for a summary of some of the important information and research findings from the Annual Meeting of the American College of Allergy, Asthma & Immunology (ACAAI), held November 11th through the 16th, 2010, in Phoenix. This year's meeting attracted over 3,000 participants from around the world. The conference highlighted advances in allergy, asthma, and immunology research, procedures, and technologies. Presentations focused on allergies to food, medications, and chemicals as well as the use of immunotherapy and steroids for the treatment of asthma.
Guest: Jay Skyler, MD
Host: Steven Edelman, MD
Can immune intervention stop the disease process of type 1 diabetes? Join host Dr. Steven Edelman and his guest, professor of medicine, pediatrics and psychology at the University of Miami, Dr. Jay Skyler, as they discuss the diagnosis, screening, testing and current immunotherapy research for the prevention and intervention of type 1 diabetes.
Host: Mark Chyna, MD
Tune in for the latest clinical information and research findings from the 2010 American Academy of Allergy, Asthma & Immunology annual meeting, February 26th through March 2nd, in New Orleans. Highlights covered food allergies, asthma in children and adults and personalized medicine.
Guest: Matthias von Herrath, MD
Host: Steven Edelman, MD
Development of a combination therapy is showing significant promise in type 1 diabetes when caught in the early stages. What are some immuno-therapies currently being evaluated for treating type 1 diabetes? Join host Dr. Steven Edelman and his guest, director of the Center for Type 1 Diabetes Research at the La Jolla Institute for Allergy and Immunology, Dr. Matthias von Herrath, as they discuss histopathology, antigen-specific therapy, anti-CD3d antibodies and more.
Host: Mark Chyna, MD
Listen to highlights from research presented at the American College of Allergy, Asthma, and Immunology's 2009 annual meeting. The meeting took place November 5th through the 10th, 2009, in Miami Beach, Florida.
Guest: Norman Edelman, MD
Host: Matt Birnholz, MD
Host: Michael Greenberg, MD
We are moving closer to the height of what many feel will be an extraordinarily busy flu season, with H1N1 and the seasonal flu both central parts of the discussion. We don't know exactly how serious H1N1 will be, but we do know that it's here, that many more people could get sick, and that we have to be prepared to deal with it. Hosts Dr. Michael Greenberg and Dr. Matt Birnholz speak with Dr. Norman Edelman, chief medical officer for the American Lung Association and a professor of preventive medicine and internal medicine at the State University of New York at Stony Brook.
Dr. Birnholz and Dr. Greenberg will also give you their take on an amusing recitation of the health reform bill in the House known as HR 3200. They will also play back the winning entry in an entertaining yet informative contest to create a public service announcement on H1N1, co-sponsored by the U.S. Department of Health and Human Services. You won't want to miss it!
Guest: Sarah Lorentz, PharmD
Host: Candis Morello, PharmD, CDE
Why are people living with diabetes more likely to die with flu and pneumonia? During flu epidemics, this risk is particularly high when additional risk factors present such as cardiovascular disease and kidney disease. Join guest host Dr. Candis Morello and her guest, pharmacist specializing in ambulatory care, Dr. Sarah Lorentz, as they discuss the reasons immunizations for patients with diabetes are so crucial.
Guest: Mansour Mohamadzadeh, PhD
Host: Jay Goldstein, MD
Researchers have developed an oral vaccine utilizing probiotics and, in preclinical studies, have found it successful in providing immunity against anthrax. Why are probiotics a good delivery component, and why might this method encourage a greater degree of response than the traditional vaccine injection? Dr. Mansour Mohamadzadeh, associate professor of medicine in the division of gastroenterology at Northwestern University Feinberg School of Medicine, tells host Dr. Jay Goldstein about this new vaccine delivery method. Will oral vaccines soon be ready for clinical trials?
Guest: Wesley Burks, MD
Host: Lee Freedman, MD
Peanut allergy is an increasing public health concern in the United States. Children with peanut allergy may remain allergic for life, unlike children with more often outgrown allergies to milk or egg. Dr. Wesley Burks, professor and chief of the division of pediatric allergy and immunology at Duke University Medical Center, describes recent success with peanut immunotherapy in a few groups of children. Do these studies provide hope for all patients with peanut allergy, including adults? Dr. Lee Freedman hosts.
Guest: John Heffner, MD
Host: Maurice Pickard, MD
Do allergies to various types of fungi trigger worsening of asthma? Are patients with severe asthma sensitive to certain species of fungus more than others? Dr. John Heffner, professor of medicine at the Oregon Health and Science University, discusses how patients with asthma might benefit from antifungal agents. Does off-label use of itraconazole for patients with severe asthma require long-term adherence for optimal asthma control? Dr. Maurice Pickard hosts.
Host: Todd Mahr, MD
Guest: Gailen D. Marshall, MD, PhD
The media often report about the effect of stress on the immune system. What research supports the idea that certain individuals are more susceptible to stress than others, and how can physicians recognize patients who might be experiencing an immunological response to stress? What mechanisms might link rhinitis, asthma and chronic urticaria to stress? Dr. Gailen Marshall, professor of medicine and pediatrics at the University of Mississippi Medical Center, discusses the fascinating relationship between a patient's mental state and immunity. Dr. Todd Mahr hosts.
Host: Todd Mahr, MD
Guest: Warner Carr, MD
What phases does the FDA use to approve a new medication, and why does this process take several years? Why must the active and excipient components of the medication, as well as the device, complete all of the testing phases? Dr. Warner Carr, allergist at Allergy and Asthma Associates in Mission Viejo, California, shares insight from his role as a new drug reviewer at the FDA. How do physicians play a vital role in the drug-approval process by providing clinical feedback to the FDA? Dr. Todd Mahr hosts.
Guest: Norman Edelman, MD
Host: Shira Johnson, MD
More than 40 thousand people, including fire and rescue workers, were exposed to toxic dust in the wake of the attacks on the World Trade Center in New York City in September, 2001. Fast-forward more than a decade, and nearly a quarter of those first responders still have breathing issues. Dr. Norman Edelman, chief medical officer of the American Lung Association, joins host Dr. Shira Johnson to disuss what needs to be done for those who continue to suffer, as well as how children living in nearby neighborhoods have also been affected. The two also look at air quality and allergy and its affect on Americans.
Guest: Robert Pass, MD
Host: Jennifer Shu, MD, FAAP
Congenital cytomegalovirus (CMV) infection causes auditory, cognitive and neurologic impairment in thousands of infants each year in the United States. Recognition of infection in pregnant women is difficult because CMV often produces few symptoms, and antiviral treatment during pregnancy may have toxic effects. Could a new experimental vaccine hold the key to preventing maternal CMV infection during pregnancy and decrease the incidence of congenital CMV infection and its sequelae? Host Dr. Jennifer Shu evaluates the progress toward a CMV vaccine with Dr. Robert Pass, professor of pediatrics and microbiology at the University of Alabama at Birmingham School of Medicine. Dr. Pass also explains the proposed mechanism of action for the vaccine.
Guest: Rob Neville
Host: Bruce Japsen
Despite medical advancements in drugs and delivery devices for asthma and allergy sufferers, some patients are not getting appropriate dosages. But new advances are being worked on that could improve care for many through nanotechnology. Rob Neville, executive chairman of Savara Pharmaceuticals, tells host Bruce Japsen about the use of nanotechnology as an emerging way to administer drugs more effectively for improved respiratory care.
Guest: Christina Robohm, PA-C
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
How does a PA handle the situation when a parent does not want to vaccinate their child? Christina Robohm, physician assistant and associate professor of pediatrics at the University of Colorado at Denver, tackles this growing issue with host Lisa Dandrea Lenell. The two discuss how PAs make sure parents receive accurate information in order to make an informed decision whether or not they want their children to receive vaccinations, the pros and cons of not vaccinating, and what it means for other children around them and the community at large. They also look at the controversy over vaccinations and autism.
Guest: Paul Offit, MD
Host: Jennifer Shu, MD, FAAP
Most parents support the immunization of their kids according to the recommended vaccine schedule. But increasing numbers are choosing to forgo this routine entirely or follow an alternative vaccine schedule. How are these vaccine practices impacting the health of our young patients and more broadly, the health of the general public?Host Dr. Jennifer Shu examines the key questions surrounding the alternative vaccine schedules and how to guide young patients and their families through this process, with Dr. Paul Offit, chief of the division of infectious diseases and director of the Vaccine Education Center at the Children's Hospital of Philadelphia, and the Maurice R. Hilleman Professor of Vaccinology at the University of Pennsylvania School of Medicine.
Guest: Harold S. Nelson, MD
Host: Jennifer Shu, MD, FAAP
The incidence of asthma has doubled in the past two decades, though the cause of this rise is difficult to pinpoint. While the hygiene hypothesis has, for years, served as one possible explanation, newer studies show a possible link between asthma and vitamin levels or exposure to certain chemicals or medications. How might this knowledge help us prevent the development of asthma, and what research still needs to be performed to determine the key factors here, and put an end to the increasing incidence of asthma? Dr. Harold Nelson, professor of medicine at the University of Colorado School of Medicine and National Jewish Health hospital in Denver, lays out the evidence for these potential risk factors, from the child's date of birth, to acetaminophen use, to vitamin D levels, to exposure to cleaning sprays and other household chemicals. Dr. Jennifer Shu hosts.
Guest: Jesse Joad, MD, MS
Host: Jennifer Shu, MD, FAAP
Long-acting, single-agent beta agonists should be used in tandem with a corticosteroid for the treatment of asthma. Despite a black box warning from the Food and Drug Administration (FDA) to this effect, evidence suggests nearly half of our patients do not take these medications together, which appears to result in more severe asthma attacks and an increased mortality risk. In theory, longer-acting beta agonists (LABAs) should help with compliance, but if these single-agent drugs aren't taken as recommended, is there a role for them in the treatment of asthma? Dr. Jesse Joad, professor of pediatrics at the University of California, Davis School of Medicine and a former member of the FDA's Pulmonary and Allergy Drug Advisory Committee, talks with host Dr. Jennifer Shu about the pharmacologic and logistical differences between LABAs taken as monotherapy and LABAs taken in combination with a steroid. Dr. Joad …
Guest: David Fleischer, MD
Host: Jennifer Shu, MD, FAAP
Wheat, eggs, milk, peanuts and other nuts, soybeans and seafood: all of these can be an integral part of a balanced, healthy diet for growing children. Instead, many are off-limits for an increasing number of children diagnosed with food allergies. Though the rise in food allergies is certainly worrisome, we're learning that some food allergies may actually be misdiagnosed. Host Dr. Jennifer Shu welcomes Dr. David Fleischer, assistant professor of pediatrics at the University of Colorado School of Medicine and National Jewish Health in Denver, for a conversation about how we can improve our capacity to accurately assess food allergies, and help many of our young patients tolerate, or even enjoy, a wider range of food. Starting with a clinical history, what kind of workup should be done before patients are referred to an allergist? How should allergen-specific antibody blood tests be incorporated into this process?
Join us for research presented at the 2009 meeting of the American Academy of Allergy, Asthma & Immunology, held March 13th through the 17th in Washington, DC.
Guest: Michael Gabay, PharmD, JD
Host: Charles Turck, PharmD, BCPS, BCCCP
Culled from human plasma, intravenous immunoglobulin (IVIG) is an expensive and limited resource. These constraints underscore the importance of ensuring that our clinical uses of IVIG are in line with the applications for which we have best demonstrated its efficacy. Yet IVIG has only amassed a short list of FDA-approved indications, and is often employed as an off-label therapy. In what areas is our use of IVIG best supported by the literature, and is this consistent with how the agent is most commonly used? Host Dr. Charles Turck examines these questions and more with Dr. Michael Gabay, clinical assistant professor at the University of Illinois at Chicago College of Pharmacy, where he directs the university's Drug Information Group and Prior Authorization Services.
Guest: Bob Baltera
Host: Bruce Japsen
Asthma remains a difficult disease to treat and control, with a large portion of the patient population not receiving adequate treatment options. But next-generation therapies are targeting this inflammation by being more targeted, getting at the root of the pathways that play a larger role in the disease. Bob Baltera, chief executive officer of Amira Pharmaceuticals, tells host Bruce Japsen about developments in more targeted therapies.
Guest: David P. Skoner, MD
Host: Ketan Sheth, MD, MBA
Is there evidence that suggests corticosteroids used to treat asthma might affect growth? Are growth effects from using inhaled or intranasal steroids to control asthma or allergic rhinitis a significant concern? Dr. David Skoner, professor of pediatrics at the Drexel University College of Medicine, discusses the challenges of evaluating the systemic effects of these medications, and suggests what physicians can do to minimize the risk of growth effects when using corticosteroids. Dr. Ketan Sheth hosts.
Guest: Michael Foggs, MD
Host: Ketan Sheth, MD, MBA
In what populations is asthma becoming more prevalent, and is asthma becoming a significant public health issue? How can physicians better care for under-served communities with a prevalence of asthma? Dr. Michael Foggs, chief of allergy, asthma, and immunology at Advocate Health Centers, discusses the impact of asthma on under-served communities, and how physicians can be mindful of related socioeconomic issues. Hosted by Dr. Ketan Sheth.
Guest: Jian Han, MD
Host: Bruce Japsen
Diagnostic tests can sometimes get to patients too late but technology is changing to treat patients early, particularly for respiratory problems and infectious diseases. Dr. Gian Han, director of Diatherex Laboratories, tells host Bruce Japsen about the diagnostic industry's progress in testing for respiratory diseases and superbugs via the latest in research and technology in molecular generics.
Host: Ketan Sheth, MD, MBA
Guest: Carlos Camargo, MD, DrPH, MPH
What's the best strategy for managing patients with chronic asthma, and how can physicians create an action plan with their patients to treat an asthma exacerbation? Host Dr. Ketan Sheth reviews recent guideline recommendations for preventing asthma exacerbations with Dr. Carlos Camargo, associate professor of medicine and epidemiology at Harvard Medical School. How are acute and chronic management of asthma different?
Host: Ketan Sheth, MD, MBA
Guest: William Lumry, MD
Hereditary angioedema is relatively rare and is often misdiagnosed as an allergic reaction to medication or food. What symptoms are helpful differentiating points for making an accurate hereditary angioedema diagnosis? Dr. William Lumry, clinical professor of internal medicine at the University of Texas Southwestern Medical School, outlines the types of hereditary angioedema, factors which can contribute to an acute attack, and therapies to prevent or treat patients with this condition. Dr. Ketan Sheth hosts.
Guest: James Sublett, MD
Host: Todd Mahr, MD
Indoor allergens can exacerbate or trigger allergic or asthmatic responses. What effect do carpeting, cleaning solutions, pets, and humidifiers have on indoor environments? Dr. James Sublett, clinical professor and section chief of pediatric allergy at the University of Louisville School of Medicine, offers tips on creating safer homes for patients with allergies. Dr. Todd Mahr hosts.
Host: Todd Mahr, MD
Guest: Sidney Braman, MD, FACP, FCCP
Chronic obstructive pulmonary disease, or COPD, is often diagnosed in late stages, as it is a slowly progressing condition. How can physicians diagnose patients with this deadly disease in its earlier stages, to increase the success of reversing some of its symptoms? Dr. Sidney Braman, professor of medicine at the Warren Alpert Medical School of Brown University, describes who is affected by COPD, and how physicians can best treat these patients. Dr. Todd Mahr hosts.
Host: Ketan Sheth, MD, MBA
Guest: William Silvers, MD
Are the symptoms of exercise-induced asthma always apparent, and if not, how can physicians diagnose the condition? Can exercise-induced asthma exist independently, or does it always signify an underlying asthmatic condition? Host Dr. Ketan Sheth discusses the pathogenesis of and treatments for exercise-induced asthma with Dr. William Silvers, clinical professor of medicine at the University of Colorado School of Medicine. Dr. Silvers will explain the phenomenon that the seemily innocuous food celery can specifically cause exercise-induced allergic reactions.
Guest: Anne Muñoz-Furlong
Host: Todd Mahr, MD
How does a food allergy diagnosis impact a patient's quality of life? What can physicians do to help patients cope with food allergies? Host Dr. Todd Mahr asks Anne Muñoz-Furlong, founder and CEO of the Food Allergy and Anaphylaxis Network, about the challenges facing patients with food allergies. How can physicians and families navigate the management of a toddler or teenager with food allergies?
Host: Todd Mahr, MD
Guest: Steven Weinstein, MD
Clinical trials are essential to the safe development of medications. How are clinical trials structured, and what are the features of the various clinical trial stages? Dr. Steven Weinstein, clinical professor in the department of pediatrics at the University of California at Irvine, provides an overview of clinical trials with host Dr. Todd Mahr. What are the ethical considerations taken into account during clinical trials?
Host: Todd Mahr, MD
Guest: Bradley E. Chipps, MD, FAAP, FACAAI, FAAAAI, FCCP
What criteria are included in the modified asthma predictive index, and how does this index help physicians diagnose young patients with wheezing and coughing? When is bronchoscopy recommended as an important diagnostic tool for evaluating pediatric lower respiratory symptoms? Dr. Bradley Chipps, medical director of respiratory therapy at Sutter Medical Center, reviews how physicians might work up a young patient with these respiratory symptoms, and suggests the most effective treatments. Dr. Todd Mahr hosts.
Host: Todd Mahr, MD
Guest: Jason Knuffman, MD
A cough that continues for more than a couple of months is considered chronic. What are the most likely causes of chronic cough in non-smoking adults, other than asthma? Dr. Jason Knuffman, allergist in the department of allergy at Gunderson Lutheran Health System in LaCrosse, Wisconsin, discusses how to avoid some common pitfalls that are often encountered when evaluating and treating adults with chronic cough. Dr. Todd Mahr hosts.
Host: Ketan Sheth, MD, MBA
Guest: Santiago Martinez, MD
What is the relationship between immunity and autism? Do the immune systems of those with autism function differently than the rest of the population? Dr. Santiago Martinez, clinical assistant professor at Florida State University College of Medicine, joins host Dr. Ketan Sheth to discuss the immune systems of autism patients. Is there any evidence that might suggest that autoimmune disorders in mothers can somehow contribute to the development of autism in their children?
Host: Ketan Sheth, MD, MBA
Guest: J. Allen Meadows, MD
How are Medicare and health insurance companies affecting physicians and their patients' access to care? What can physicians do to influence policy at the local level? Dr. J. Allen Meadows, clinical instructor in the Montgomery Internal Medicine Residency Program at the University of Alabama at Birmingham, suggests ways allergists and other physicians can get involved with their communities and shape policies affecting how physicians care for their patients. Dr. Ketan Sheth hosts.
Host: Ketan Sheth, MD, MBA
Guest: Renata Engler, MD
How do insect allergies present challenges in emergency situations to first responders? What are the best ways to diagnose and treat anaphylaxis in patients away from a clinical setting? Host Dr. Ketan Sheth talks with Dr. Renata Engler, associate professor in the department of medicine at the Uniformed Services University of the Health Sciences, about treating insect allergy in the field. How is proper transport and storage of epinephrine particularly difficult for those in the military or others traveling to remote locations, and what can physicians do to ensure safety for patients in these situations?
Host: Lee Freedman, MD
Guest: Frederick Vivino, MD
Sjogren's syndrome is a commonly overlooked autoimmune disorder. Dry eyes and whole-body dryness are just two of the symptoms of Sjogren's syndrome that can suggest other conditions as well. How does Sjogren's present itself beyond dry eyes, and how severe is the condition? Dr. Frederick Vivino, clinical associate professor of medicine at the University of Pennsylvania School of Medicine, describes some of the tests and therapies available for Sjogren's syndrome to host Dr. Lee Freedman.
Produced in Cooperation with
Host: Ketan Sheth, MD, MBA
Guest: I. Leonard Bernstein, MD
The Joint Task Force on Practice Parameters for the Diagnosis and Treatment of Asthma has revised its allergy diagnostic testing parameters. What are the parameters trying to establish? What are the advantages of intracutaneous, skin prick, and in vitro testing for diagnosing allergies? Dr. I. Leonard Bernstein, co-director of the allergy research laboratory in the department of medicine at the University of Cincinnati Medical Center, and co-author of the parameters, explores allergy diagnostic testing options with host Dr. Ketan Sheth.
Guest: Richard Nicklas, MD
Host: Ketan Sheth, MD, MBA
What are the scenarios that characterize anaphylaxis, according to the National Institute of Health? Dr. Richard Nicklas, clinical professor of medicine at George Washington University Medical Center, discusses the manifestations of anaphylaxis and how physicians can best manage patients with a history of anaphylaxis. Dr. Ketan Sheth hosts.
Host: Todd Mahr, MD
Guest: Scott Sicherer, MD
Because more children now live with food allergies than in decades past, at what point should a physician suspect that a patient might have a food allergy? What gastrointestinal symptoms are most common in children with food allergies? Dr. Scott Sicherer, associate professor of pediatrics at Mount Sinai School of Medicine in New York, reviews the most effective ways to diagnose and manage children with food allergies. Surprisingly, Dr. Sicherer says skin prick testing should not be the first diagnostic step. So what should physicians do when they suspect a child might have food allergies? Dr. Todd Mahr hosts.
Guest: Jonathan Spergel, MD, PhD
Host: Todd Mahr, MD
One of the most common and frequently misdiagnosed eosinophilic gastrointestinal diseases is eosinophilic esophagitis. When should a physician suspect eosinophilic esophagitis, and how can it be accurately diagnosed? How significant a factor is diet in such disorders? Dr. Jonathan Spergel, associate professor of pediatrics at the University of Pennsylvania School of Medicine, delves into the potential causes of eosinophilic gastrointestinal diseases with host Dr. Todd Mahr.
Host: Todd Mahr, MD
Guest: Stanley Fineman, MD, MBA
Immunoglobulin replacement therapy has been used for treating various infections over the past 50 years. It has been traditionally administered intravenously, but now subcutaneous delivery of immunoglobulin is proving to be an attractive alternative. What disorders are immunoglobulin therapy used to treat, and what are the advantages to each type of preparation? Dr. Stanley Fineman, clinical associate professor in the department of pediatrics at Emory University School of Medicine, discusses novel approaches to immunoglobulin therapy with host Dr. Todd Mahr. Which patients are the best candidates for immunoglobulin therapy?
Host: Todd Mahr, MD
Guest: Clifford Bassett, MD
Gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) are both conditions stemming from acid reflux, but can manifest with different symptoms. What other health problems can be tied to LPR and GERD, and how can we determine the difference between the two? Dr. Clifford Bassett, assistant clinical professor of medicine and otolaryngology at the Long Island College Hospital and faculty member at the NYU School of Medicine, explains the characteristics of both conditions with host Dr. Todd Mahr.
Host: Todd Mahr, MD
Guest: Alan Goldsobel, MD
Cough is one of the most common symptoms but can develop as a symptom of various disorders, from asthma to bacterial infection to gastroesophogeal reflux disorder. How important is the character of a cough in determining the cause in children particularly? Host Dr. Todd Mahr explores cough guidelines and recommendations for children, alon with Dr. Alan Goldsobel, clinical professor in the department of medicine at the University of California San Francisco. At what point is a cough considered chronic, and when should a lingering cough be evaluated in children?
Guest: William Calhoun, MD, FACP, FCCP, FAAAAI, FACAAI
Host: Ketan Sheth, MD, MBA
There are numerous different asthma phenotypes, such as exercise-induced asthma and severe asthma. How does understanding the specific asthma phenotype help indicate which therapies might work best for a patient? What are the various biomarkers that can indicate asthma, and which ones can be used clincially? Dr. William Calhoun, chair of internal medicine and vice chair for research in the department of internal medicine at the University of Texas Medical Branch in Galveston, Texas, discusses the relationship between asthma phenotypes and biomarkers with host Dr. Ketan Sheth.
Host: Ketan Sheth, MD, MBA
Guest: Amy Branum, MSPH
The first federal study of food allergies in children by the Centers for Disease Control (CDC) found a steep increase in such allergies over the last decade. What accounts for the rise in diagnoses and hospitalizations? Is the severity of food allergies also increasing? Amy Branum, lead author of the CDC's study and a statistician at the National Center for Health Statistics, illustrates recent figures on pediatric food allergies with host Dr. Ketan Sheth.
Host: Ketan Sheth, MD, MBA
Guest: Stanley Fineman, MD, MBA
The role that biomarkers can play in asthma control by effectively measuring lung inflammation is a topic that has begun to get more attention lately in medical journals. Although use of most biomarkers is not clinically pragmatic for physicians yet, guest Dr. Stanley Fineman, clinical associate professor in the Department of Pediatrics at Emory University School of Medicine, predicts that biomarkers will likely play a more significant role in the future. Host Dr. Ketan Sheth asks, what other methods are most effective for monitoring control in asthma?
Host: Ketan Sheth, MD, MBA
Guest: Sami Bahna, MD, DrPH
Why are so many people allergic to peanuts? Can people have an allergy to a specific food the very first time they consume it? Both the types of food allergies and the numbers of individuals affected by food allergies increase every year. There are many potential reasons for the rise in food allergies, including the amount of food people consume and the variety of ingredients in what we eat. What other factors are involved in the development of food allergies? Dr. Sami Bahna, Professor of Pediatrics and Medicine as well as the Chief of the Allergy and Immunology Section at Louisiana State University Health Sciences Center, explores the realities of food allergies with host Dr. Ketan Sheth.
Host: Ketan Sheth, MD, MBA
Guest: John Oppenheimer, MD
Although asthma is chronic, it is treatable. The new asthma guidelines demonstrate a shift in attitudes. Whereas we used to assess the severity of the condition, now we ask how well it is controlled. Dr. John Oppenheimer, director of clinical research at Pulmonary and Allergy Associates as well as clinical associate professor of medicine at the New Jersey Medical School in Newark, New Jersey, explores the best ways to follow asthma control with host Dr. Ketan Sheth.
Guest: Jay Berkelhamer, MD
Host: Jennifer Shu, MD, FAAP
The medical community provides a vital public health service when we vaccinate our patients. However, this practice is often a money-losing proposition for us, as evidenced by the many primary care physicians who are discontinuing immunizations in their practice. What can physicians, vaccine manufacturers and insurers do to improve the current vaccine financing and delivery system? Dr. Jay Berkelhamer, senior vice president and chief academic officer at Children’s Healthcare of Atlanta, and past president of the American Academy of Pediatrics, joins host Dr. Jennifer Shu to explores a series of ways through which organizations and workers throughout the healthcare community can do their part to improve our system for financing vaccines.
Host: Ketan Sheth, MD, MBA
Guest: Jay Portnoy, MD
Molds are unique organisms that surround us, yet there is growing concern about how molds can impact our health. What sorts of bodily reactions are linked to molds? Should we be worried about adverse health effects from all molds or are some generally safe? Dr. Jay Portnoy, chief of allergy, asthma and immunology at Children's Mercy Hospitals and Clinics and professor of pediatrics at the University of Missouri-Kansas City School of Medicine, discusses the realities of ever-present molds with host Dr. Ketan Sheth.
Guest: Lisa A. Jackson, MD, MPH
Host: Maurice Pickard, MD
Do influenza vaccines for the elderly really make a difference? Dr. Lisa Jackson, research professor of epidemiology at the University of Washington and senior investigator at The Center for Health Studies in Seattle, Washington calls into question previous documentation of reducing deaths and hospitalizations in the elderly from flu vaccination. This is based on a fundamental difference between the kinds of people who get vaccines and those who do not. Join host Dr. Maurice Pickard to learn more.
Guest: James Crowe, MD
Host: Mark Nolan Hill, MD
Preparing for the future by studying the past: With researchers now able to resurrect antibodies to the 1918 influenza pandemic from elderly survivors, how does the technology used to do this potentially lead us to antibodies for other viruses? Can we be sure this immunity is not generated by recent exposure to similar strains? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, explains how we are beginning to learn more about where viruses, including HIV, are most susceptible to being controlled and destroyed. Dr. Mark Nolan Hill hosts.
Host: Mark Nolan Hill, MD
Guest: James Crowe, MD
Ninety-plus years after the 1918 influenza pandemic, we are just beginning to understand the naturally occurring adaptive immunity of those who were in contact with this devastating virus. As researchers probe survivors of the flu pandemic, all of whom are approaching or have attained centenarian status, what are we learning about their long-lasting immunity to this virus? Can we explain why these people survived this expansive outbreak, just as relatives and friends around them perished? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, shares some of the tricks that his team has used to make these antibodies in this fascinating discussion with Dr. Mark Nolan Hill.
Guest: James Crowe, MD
Host: Mark Nolan Hill, MD
First published in 2005, the story of how we've come to understand the complete sequence of the 1918 pandemic influenza virus begins years ago, in a remote Alaskan village, and continues today in research across the country. What are we learning about a virus that has taken many decades to comprehend? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, tells host Dr. Mark Nolan Hill that antibody recognition may actually bear a strong resemblance to cognitive memory. What does Dr. Crowe mean by this? Do we know how the immune system would respond if survivors were infected with this influenza virus?
Guest: Sheila Crowe, MD
Host: Jay Goldstein, MD
Food allergies are becoming increasingly common. Such allergies are often not easy to diagnose, and can present differently in adults and children. What is the difference between a food allergy and a specific food intolerance? What causes food allergies, and are there effective treatments beyond avoidance? Host Dr. Jay Goldstein probes the truth about food allergies with Dr. Sheila Crowe, professor of medicine in the division of gastroenterology and hepatology at the University of Virginia.
Guest: Ken Fitch, MD
Host: Mary Leuchars, MD
Dr. Mary Leuchars is joined by guest Dr. Ken Fitch, past-Chairperson of the Australian Olympic Committee's Medical Commission and current member of the Medical Commission of the International Olympic Committee. The topic is asthma in elite athletes, and Dr. Fitch shares insights on how the Australian Olympic team's physicians assess, treat, and prepare their top competitors to perform in Beijing's hot climate conditions.
Host: Ketan Sheth, MD, MBA
Guest: Stuart Stoloff, MD
For the first time in 10 years, the guidelines for allergy management have been significantly updated. With the goal of optimizing asthma control for every patient, how were the new guidelines created, and how should they be applied? Dr. Stuart Stoloff, a family practitioner from Carson City, Nevada, and member of the National Asthma Education and Prevention Program’s Expert Panel 3, speaks with your host, Dr. Ketan Sheth on the creation of the new guidelines and their application in the exam room.
Guest: Richard Ransohoff, MD
Host: Leslie P. Lundt, MD
Chemotactic cytokines (known as chemokines) are small proteins that direct the movement of leukocytes to sites of inflammation or injury. An explosion of information about chemokines and their receptors has occurred in recent years. Dr. Richard Ransohoff tells host Dr. Leslie Ludnt what is happening in this exciting field.
Host: Todd Mahr, MD
Guest: William Berger, MD
Guest: Bradley E. Chipps, MD, FAAP, FACAAI, FAAAAI, FCCP
Recent research confirms adolescent asthma and obesity directly correlates with significant risk of adult asthma. Does obesity impact the therapy response rate? Which current devices confer precise delivery of medication? Host Dr. Todd Mahr guides a dialogue with Dr. Bradley Chipps, medical director of the Capital Allergy & Respiratory Disease Center in Sacramento, Calif., and Dr. William Berger, medical director of the Allergy and Asthma Associates of Southern California.
Host: Todd Mahr, MD
Guest: Ketan Sheth, MD, MBA
Dr Ketan Sheth was one of the advisors on the Pediatric Allergies in America survey. This was the largest and most comprehensive national survey of parents of allergy sufferers, allergy sufferers under age 18, and health provider perspectives concerning allergic rhinitis. The survey was designed using the same methods and many of the same measures as Allergies in America (2006). A number of important conclusions about the current state of nasal allergies among American children are:
- Nasal congestion was the most frequent and bothersome symptom for children with allergies;
- Children suffer considerable discomfort during allergy attacks, such that one third of parents reported their child’s discomfort was not tolerable without relief;
- Impact of nasal allergies to a child’s productivity is considerable with an average loss of 29% among children with allergies on days when their allergies are at their worst;
- Patient non-compliance with prescribed treatment for the condition is driven more by dissatisfaction with product effectiveness and duration, than side effects, cost or ease of administration;
- Doctors and parents agreed that better education of parents about their child’s condition and treatment of allergic rhinitis is important.
The findings from the Pediatrics Allergies in America survey identify important challenges …
Guest: Dean Metcalfe, MD
Host: Bill Rutenberg, MD
What are the causes, treatments and cure for peanut allergy. Join host Bill Rutenberg interview Dr. Dean Metcalfe to learn more.
Guest: Dean Metcalfe, MD
Host: Bill Rutenberg, MD
Could your patient be allergic to excercise? What happens in the body and is there an excercise/food relationship that causes anaphylaxis or alternative allergic reaction after excercise? Join host Dr. Bill Rutenberg learn more in his interview with Dr. Dean Metcalfe.
Guest: Dean Metcalfe, MD
Host: Bill Rutenberg, MD
While it may look like an allergy, many times it is not. Join host Dr. Bill Rutenberg and guest Dr. Dean Metcalfe sorting out what is an allergy and what is not.
Guest: Dean Metcalfe, MD
Host: Bill Rutenberg, MD
In this segment, Dr. Dean Metcalfe discusses why allergies are more prevelent in children today. He considers the role of genetics and our environment. He also talks about the best preventative measures for food allergies.
Host: Todd Mahr, MD
Guest: Stephen Tilles, MD
Aspirin is something widely used in everyday practice, and generally well-tolerated. Yet, potentially serious adverse effects - sometimes leading to hospitalization - exist. Who's at risk? What are the symptoms, and can Aspirin desensitization work for all patients? Join Dr. Todd A. Mahr as he speaks with Dr. Stephen Tilles, clinical assistant professor at the University of Washington School of Medicine, in a discussion of aspirin intolerance.
Host: Todd Mahr, MD
Guest: Stephen Tilles, MD
How common is Aspirin Intolerance? When was it first discovered, and what are the clinical manifestations? Dr. Stephen Tilles, clinical assistant professor at the University of Washington School of Medicine, joins Dr. Todd A. Mahr to discuss aspirin intolerance, highlighting symptoms and provocative testing.
Guest: Magdalena Pasarica, PhD
Host: Paul Raeburn
An estimated 97 million Americans are overweight--one in three of us. Some of that is due to genetics. But overweightness and obesity have exploded during the past two decades--and genes likely can't account for this. Before you put all the blame on Twinkies, however, think again: Our guest today suggests that a virus might be contributing to the obesity epidemic. Hosted by Paul Raeburn.
Guest: Barjor Gimi, PhD
Host: Bruce Bloom, DDS, JD
Dr. Gimi discusses his micro-container patent and related research focused on encapsulated cell based therapies.
Guest: Barjor Gimi, PhD
Host: Bruce Bloom, DDS, JD
Dr. Gimi discusses his research focused on encapsulated cell based therapies, and how it compares to what others are doing in the field.
Guest: Barjor Gimi, PhD
Host: Bruce Bloom, DDS, JD
We cage animals to keep them safe from us and us from them. What if we caged transplanted cells to keep them safe from our immune system and vice versa? Dr. Gimi discusses his research focused on encapsulated cell based therapies.
Host: Todd Mahr, MD
Guest: Phillip Lieberman, MD
Join Dr. Todd Mahr as he interviews Dr. Phil Lieberman, lead author of "SAFE: A Multidisciplinary Approach to Anaphylaxis in the Emergency Room Department" that was published in the Annals of Allergy, Asthma, and Immunology.
Guest: Marc Rothenberg, MD
Host: Bill Rutenberg, MD
In this segment, Dr. Rothenberg talks about the physiology of a food allergy and then updates us on some of his current research findings related to the genetics of EOS.
Host: Larry Kaskel, MD
Guest: Elizabeth Tieman, MD
Work-life balance: how many of us can say we have it, let alone come close to having it? Board-certified radiologist Dr. Betsy Tieman is one healthcare professional who can say she achieved work-life balance by leaving private practice where she was working 14 hours a day to take advantage of locum tenens work, which also enabled her to train and compete in triathlons.
Guest: J. Lee Nelson, MD
Host: Michael Benson, MD
Fetal cells persisting in maternal tissues for 50 years and then causing a graft versus host reaction? Medicine does not get more bizarre, but this seems to be the case for systemic sclerosis. Dr. Nelson examines the growing evidence to support this new look at some of the "auto-immune" diseases.
Guest: Michael Blaiss, MD
Host: Todd Mahr, MD
Dr. Mahr and Dr. Blaiss discuss a recent article published in the Annals of Allergy, Asthma and Immunology focusing on allergic rhinitis and sleep disorders.
Guest: Clifford Bassett, MD
Host: Larry Kaskel, MD
Dr. Clifford Bassett, Allergist and Assistant Clinical Professor of Medicine and Otolaryngology at Long Island College Hospital in New York speaks about the "why" behind food allergies and cultural factors affecting the field.