Cell Podcast: Recent Episodes
Cell Press
Cell (www.cell.com) is a peer-reviewed journal publishing the most interesting discoveries in biology.
In this edition, we'll hear about how heritability traits can be inferred from electronic medical records, with Nick Tatonetti and Fernanda Polubriaginof, Cell (00:00); why fiber does wonders for your immune system, with Benjamin Marsland, Immunity (9:56); and what's behind the high-energy demands of mining Bitcoin, with Alex de Vries, Joule (18:56).
In this edition, we’ll hear about how heritability traits can be inferred from electronic medical records, with Nick Tatonetti and Fernanda Polubriaginof, Cell (00:00); why fiber does wonders for your immune system, with Benjamin Marsland, Immunity (9:56); and what’s behind the high- energy demands of mining Bitcoin, with Alex de Vries, Joule (18:56).
In this episode, we’ll hear about why you might want to be skeptical of raw water, with Gail Teitzel, Editor of Trends in Microbiology (00:00); how brain chemistry might change in mice as a result of social isolation, with David Anderson, Cell (07:45); and what’s unusual about neurons in people with severe obesity, with Dhruv Sareen, Cell Stem Cell (17:10). Then, stay tuned for our monthly news roundup, including using MRI to predict risk tolerance; rethinking what we know about genetics, sugar, and weight gain; and how the sweet potato arrived in Polynesia (26:13).
In this episode, we’ll hear about when children start to think about their reputations with Ike Silver, Trends in Cognitive Sciences (00:00); an indigenous people in Indonesia whose unusually large spleens enhance their free-diving ability with Melissa Ilardo, Cell(08:56); how the Pan-Cancer Atlas was put together, with Bob Kruger, Deputy Editor of Cell (17:55); and what’s unique about iScience, Cell Press’s newest research journal, with its Lead Editor Stefano Tonzani and Publisher Simanta Buck (24:10). Then, stay tuned for our monthly news roundup, including graphene hair dye, adaptive behaviors in the mouse brain, and improving indoor air quality with plants (32:20).
In this edition, we'll hear about new methods to monitor cannabis use, with Marilyn Heustis, Trends in Molecular Medicine (00:00); old tales of rabbit’s domestication, with Greger Larson, Trends in Ecology & Evolution (12:19); "walking fish" and the neural origins of land locomotion, with Jeremy Dasen, Cell (20:14); and how to balance safety and civil rights in access to personal genomic data, with Barbara Evans, AJHG (27:05). And this month’s news roundup: deep learning retinal diseases, wood carbon sponges, and batteries that withstand the coldest temperatures (36:15).
In this episode, we’ll hear about using DNA forensics to combat rhinoceros poaching, with Cindy Harper, Current Biology (00:00); how to save energy simply by staying at home, with Ashok Sekar, Joule (09:14); and how Cell Press is leading the way in transparency and openness in scientific publication, with Debbie Sweet, Vice President of Editorial at Cell Press (14:14). We’ll also hear a roundup of lab-grown hairy skin, surprising social preferences among bonobos, and universality in human song (22:41).
Listen to a sendoff interview with Emilie Marcus, as she recounts her personal trajectory as CEO and Editor-in-Chief of Cell, and reflects on the philosophy and strategy of Cell Press in today’s ground of scientific publishing.
In this edition, we’ll hear about a new technique to inject information into the brain of monkeys, with Kevin Mazurek and Marc Schieber, Neuron (00:00); how to convert yogurt waste into biofuels, with Lars Angenent, Joule (9:31); why should we eat a high-fiber diet, with Fredrik Bäckhed, Cell Host & Microbe (16:45); and how CRISPR holds promise for epigenetic therapies, with Hsin-Kai Liao, Cell (22:09).
In this edition, we’ll explore the reasons why so many mammoth skeletons are male, with Love Dalén, Current Biology (00:00); what happens to dwarf mongooses when they immigrate to another community, with Andrew Radford, Current Biology (9:25); and an accidental experiment in open-access publishing from Cell Reports, with Editor Stephen Matheson (16:30).
In this edition, we’ll hear about a new technique to store clean energy with Yet-Ming Chiang, Joule (00:00); how gut bacteria in wild mice are different from lab mice and what that means for interpreting research, with Stephan Rosshart and Barbara Rehermann, Cell (9:25); and why your paper may be taking a long time in peer review and what you can do about it (16:30).
In this edition, we'll hear about a new technique to store clean energy with Yet-Ming Chiang, Joule (00:00); how gut bacteria in wild mice are different from lab mice and what that means for interpreting research, with Stephan Rosshart and Barbara Rehermann, Cell (9:25); and why your paper may be taking a long time in peer review and what you can do about it (16:30).
In this edition, we hear about whether your genes influence your risk of tooth decay, with Karen Nelson fromCell Host & Microbe (00:00); a possible roadmap for making the world run on clean energy by 2050, with Mark Jacobson from Joule (10:00); and a look at how the collaborative peer review process works with Editor Ruth Zearfoss (26:15).
In this edition, we hear about how bacteria may influence the reproduction of other species, with John Clardy and Nicole King from Cell (00:00); how new technology is making windows smart about light and temperature, with Michael McGehee from Joule (10:35); and a behind-the-scenes peek at first year of the new journal Chem with Editor Rob Eagling (18:15).
In this edition, we hear about a new hacker-based approach to solving healthcare problems with Christopher Lee from Cell Systems (00:00); how elephant seals use rhythm to communicate, with Isabelle Charrier from Current Biology (9:15); what neuroscientists can teach us about concussions, with Christopher Giza from Neuron (16:30); and tips on how to write a great scientific abstract with Brian Plosky (24:50).
In this edition, we hear about a new topical drug that has the ability to darken the skin, with David Fisher, from Cell Reports (00:00); how sense of smell may be tied to metabolism and weight control, with Andrew Dillin, from Cell Metabolism (12:08); and tips on how to make the most out of your next scientific conference, with Shawnna Buttery (19:15).
In this edition, we’ll hear about a caterpillar that eats plastic with Paolo Bombelli and Christopher Howe, Current Biology (01:10); what researchers found when they recorded from students’ brains during a biology class with David Poeppel, Current Biology (09:22); how an artificial tongue can identify different whiskeys with Uwe Bunz, Chem (17:52); what anti-flu compounds may lurk inside a species of frog with Joshy Jacob, Immunity (23:07); and some personal reflections on the March for Science, with Stephen Matheson (28:12).
In this edition, we learn about how sleep changes with age, with Matthew Walker Neuron (00:00), how a genetic mutation in some people is linked to “night owl” behavior with Mike Young Cell (11:40), and what obese fruit flies can teach us about the relationship between weight and the weather, with Aurelio Teleman Developmental Cell (18:50).
In this edition, we take a look at the science behind superhuman memory and whether it’s trainable, with Martin Dresler, Neuron (0:00); how happy parrots spread their good humor, with Raoul Schwing, Current Biology (10:40); and how environmental conservation efforts can help spread peace, with Alexandre Roulin, Trends in Ecology and Evolution (16:40). Also, Editor Milka Kostic shares advice on how to give a great scientific presentation (24:00).
In this edition, we learn about how synthetic pot carries more dangers than traditional marijuana, with Paul Prather and Bill Fantegrossi, Trends in Pharmacological Sciences (0:00), and how bacteria can be manipulated to generate energy, with Guillermo Bazan, Chem (12:30). We’ll also take a look at how animals with very different visual systems see the world with Jennifer Levine (19:40).
In this edition, we find out why female killer whales are one of only three species to undergo menopause, with Darren Croft, Current Biology (0:00) and how the vaginal microbiome influences a woman’s risk for HIV, with Douglas Kwon, Immunity (9:40), and TiCS editor Rebecca Schwarzlose shares advice on how to write a Review article that people will rush to read (17:10).
In this edition, we’ll hear about a child mummy that reveals surprising news about the smallpox virus with Hendrik Poinar, Current Biology (0:00), a new technique to eliminate fear memories from the brain with Wu-Zhou Yang, Neuron (10:10), the scoop on the Reviews Portal at Cell Press (17:15), and a round-up of science-themed book recommendations from readers at Cell Press (19:50)!
In this edition, we learn about the superhighway of nerves that connects the two halves of the human brain with Ilan Gobius, Cell Reports (0:00), why naked mole rats don’t feel pain with Gary Lewin, Cell Reports (8:00), and the prospects for unisex birth control with Polina Lishko, Trends in Biochemical Sciences (14:40).
We have some hair-raising pieces this month, starting with a timely look at how voters make decisions about which candidate to support, with Libby Jenke and Scott Huettel, Trends in Cognitive Sciences (00:00); how a newly discovered gut protist protects mice from Salmonella, with Aleksey Chudnovskiy Cell (8:55); and a true story from one Cell Press employee who survived a lightning strike while camping with her kids CrossTalk (15:00). Plus, insight into how snakes lost their legs and much more!
Should you feed a cold and starve a fever? We’ll see what the science says, with Ruslan Medzhitov, Cell(00:00). Also, just in time for Oktoberfest: a look at the history of beer yeast, with Kevin Verstrepen, Cell (6:15). Finally, a STAR is born as Cell Press unveils a new approach to the methods section. Find out what’s changing, and how it’s designed to help you, with Ann Goldstein (13:10).
In this edition, we’ll discuss why the street drug ecstasy deserves research as a potential therapeutic, with Robert Malenka, Cell (00:00); how fiction might be good for you, with Keith Oatley, Trends in Cognitive Sciences (8:35); and why we get breast or colon cancer, but not heart cancer, with Frédéric Thomas, Trends in Cancer (18:30).
In this edition, we’ll discuss the controversy over direct-to-consumer stem cell sales, with Leigh Turner and Paul Knoepfler, Cell Stem Cell (00:00); how building design can impact your respiratory health, with Jordan Peccia, Trends in Microbiology (10:10); the complex link between Alzheimer’s disease and the immune system, with Morgan Sheng and Felix Yeh, Neuron(16:15); and an eye-opening look at the risky business of experimenting on yourself (25:30).
In this edition, we learn about possible effects on men’s health as they shed some of their Y chromosome with age, with Lars Forsberg, American Journal of Human Genetics (00:00); how human learning strategy might enhance artificial intelligence in robots, with Jay McClelland, Trends in Cognitive Sciences (8:10); and how disease reservoirs lurk in the animals around us, with Barbara Han, Trends in Parasitology (15:25). We also have a chat about the new book Welcome to the Microbiome (22:30).
In this edition, we learn some surprises about the stability of the skin microbiome, with Julia Oh and Heidi Kong, Cell (00:00), and how antibiotics can cause long-lasting disruption in the normal functions of helpful gut microbes, with Eric Pamer and Simone Becattini, Trends in Molecular Medicine (11:30). Plus, we have a slew of science highlights from around Cell Press (19:30)!
In this edition, we learn how HIV is linked to premature aging, with Trey Ideker, Molecular Cell (00:00); how seeing and perceiving visual information isn’t actually the same thing, with Michael Cohen, Trends in Cognitive Sciences (7:48); how ancient trees need special conservation, with William Laurance, Trends in Ecology and Evolution (13:10); and how the salary gap persists between men and women (19:10). Plus much more!
In this edition, we learn how the Zika virus affects fetal development, with Guo-li Ming, Hongjun Song, and Hengli Tang, Cell Stem Cell (00:00), how fungi may be used to create batteries, with Geoffrey Gadd, Current Biology(5:45), how organs can be mimicked with chip technology, with Donald Ingber, Cell (11:40), and a personal story about travel and the Zika threat, with Simanta Buck (18:05). Plus much more!
In this edition, we’ll hear about genes that modulate sleep, with David Prober, Neuron (00:00), how jogging may reduce cancer risk, with Pernille Hojman, Cell Metabolism (6:20), gene editing to fight mosquitos, with Jake Tu and Zach Adelman, Trends in Parasitology (12:40), and top myths about peer reviewers, with Cell Editor-in-Chief Emilie Marcus (19:48). Plus much more!
In this edition, we’ll hear about how some of our immunity genes are passed down from Neanderthals, with Lluis Quintana-Murci, The American Journal of Human Genetics (00: 00), whether chimps trust their friends, with Jan Engelmann, Current Biology (6:25), the 40th anniversary of Trends in Biochemical Sciences, with Nicole Neuman (16:05), and considerations for job-seeking postdocs (24:30). Plus much more!
Last November, Cell published a popular study explaining how the glycemic response to foods can differ greatly by individual. This landmark paper on personalized nutrition has since yielded follow-up research and a perspective on how our gut microbes play a role in our individual responses to diet. Catarina Sacristan discusses the findings with Eran Elinav and Eran Segal of the Weizmann Institute of Science.
Related Papers: Cell Host & Microbe, Zmora, Zeevi, and Korem et al.: Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease; Cell, Levy and Thaiss et al.: Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling; Cell, Zeevi and Korem et al.: Personalized Nutrition by Prediction of Glycemic Responses
In this edition, we’ll hear about quantitative techniques to study single cells (00: 00 with Rick Horowitz, Trends in Cell Biology), giant cells and how they behave (9:35 with Admar Verschoor and Ronny Milde, Cell Reports) and round-up of hot research stories from Cell Press (19:00).
In this edition, we’ll hear about how cell growth becomes aggressive and morphs into cancer (00:00) Developmental Cell, a possible blood test to detect cancer (10:40), new information about an old foe: the plague! (11:10), engineering banana proteins to fight viruses (11:45) and children raised without religion may be more generous (12:30).
In this edition, we’ll hear about what happens after a mass extinction event (00:00, Current Biology), how cells destroy pathogens without damaging themselves (10:25, Cell Reports), how bacteria can evade our immune system (18:35, Cell Host and Microbe), and a round-up of great science stories from Cell Press this month! (27:27).
In this edition, we’ll hear about the launch of Trends in Cancer (00:00, Trends in Cancer), a new look for Trends journals (5:40 Trends), how the brain tackles complex tasks, with Pieter Roelfsema (9:55 Neuron) and a round-up of great science stories from Cell Press this month! (17:00).
In this edition, we’ll learn about how cells share their inner selves, with Gregory Jedd (00:00 Developmental Cell), how the structure of ceramides reveals more about their function, with Michael Airola and Yusuf Hannun (6:24 Structure) and exciting scientific findings and advances published across Cell Press journals this month! (15:15)
How our brain’s working memory actually works, with Mark Stokes (00:00 Trends in Cognitive Sciences). How synthetic biology can contribute to new approaches to cancer treatment, with Wilson Wong (9:15 Trends in Biotechnology), plus a round-up of great science stories from Cell Press this month! (17:35).
How stem cells can be used to model and understand heart disease, with Joseph Wu (00:00 Cell Stem Cell). How clinicians consider the risk of heart-related side effects when treating cancer patients with chemotherapy drugs, with Michael Ewer (11:20 Trends in Pharmacological Sciences), plus a round-up of great science stories from Cell Press this month! (20:52).
In this edition, we’ll learn about how new tools for genetic editing are transforming the study of biology, with Jennifer Doudna (00:00 Molecular Cell), how the female body may ‘remember’ pregnancy, with Gregory Hannon (8:20 Cell Reports) and how to train your neuroscientist, with Brian Litt (14:20 Neuron) and a round-up of great science stories from Cell Press this month! (22:18).
In this edition, we learn about how microbes in our gut help us keep to a daily schedule, with Vanessa Leone and Eugene Chang (00:00) (Cell Host & Microbe), designing drugs that influence cyclic AMP, with Stephen Yarwood (10:57) (Trends in Pharmacological Sciences) andaround-up of recent research highlights from around Cell Press (17:30).
How the neurons in our brains that sense food might control other complex behaviors, with Marcelo Dietrich (00:00) (Cell), about actionable strategies for advancing women in STEM fields, with Susan Soloman (7:48) (Cell Stem Cell), and recent research highlights from around Cell Press (16:48).
How a "welding protein" might be a therapeutic target for many diseases, with Jeffrey Keillor (00:00) (Trends in Pharmacological Sciences), how small changes in the environment can have big impacts on developing embryos, with Anthony Hyman and Maria Begasse (9:30) (Cell Reports) and research highlights from around Cell Press (15:50).
In this edition, we learn about new research into drugs to combat antibiotic resistance, with Eric Oldfield (0:00) (Trends in Pharmacological Sciences), what sea anemones can teach us about embryonic development, with Fabian Rentzsch (9:41) (Cell Reports) and more great research highlights from around Cell Press (16:33).
In this edition, we learn about about how the poison botulinum toxin alters cell functions, with K. Ravi Acharya (00:00) (Trends in Biochemical Sciences), how recording electrical activity from neurons in awake humans, with Rodrigo Quian Quiroga (8:20) (Neuron) and how dynamic changes in genetic material called chromatin control key features of cell function, with Tom Misteli (15:35) (special issue of Trends in Cell Biology). Plus more great research highlights from around Cell Press (25:00).
In this edition, we learn about about recent discoveries that may explain how gut bacteria can affect brain development, with Michael Fischbach (0:00) (Cell Host and Microbe). A celebratory conversation as the journal Chemistry and Biology marks its 20th anniversary, with Hiroaki Suga and Milka Kostic (9:04) (Chemistry and Biology). More great research highlights from around Cell Press (15:03).
In this edition, we learn about how in drug discovery, sometimes bias is a good thing, with Jonathan Violin (0:00) (Trends in Pharmacological Sciences), how crayfish turn blood cells into neurons, with Barbara Beltz (9:35) (Developmental Cell) and more great research highlights from around Cell Press (17:45).
In this edition, we learn about how the names we call white blood cells can affect how we think about them, with Peter Murray (0:00) (Immunity), how organisms know when to stop growing, Kenneth Irvine (9:20) (Cell Reports), and more great research highlights from around Cell Press (16:00).
In this edition, we learn about how dietary changes can affect stem cells in the blood, leading to possible therapeutic opportunities, with Valter D. Longo (00:00) (Cell Stem Cell), what's new in FENS, neuroscience in Europe, and women in academia with Marian Jouls (7:33) (Neuron) and more great research highlights from around Cell Press (16:35).
In this edition, we learn about why limbs happen–or don't–for some animals, with Jeremy Dasen (0:00) (Developmental Cell). How stress can build up over a whole lifespan, with Pat Monaghan (7:50) (special issue of Current Biology). Other great research highlights from around Cell Press (15:15).
In this edition, we learn about: Battling the serious immune reaction that happens with sepsis, with Peter Ward (special issue of Trends in Molecular Medicine). The link between cell metabolism, fertility, and lifespan, with Shawn Ahmed (6:30) (Cell Reports). Other great research highlights from around Cell Press (12:00).
Listen to the Editor of Cell, Emilie Marcus, explore the history of the journal and the roots of Cell's ongoing commitment to a strong editorial voice, as well as the new horizons of biology, in an interview with long-time Cell author, reviewer, and reader, Tony Hunter from the Salk Institute (0:00) (Cell). Learn about the possible links between retroviruses and cancer, with John Coffin (9:40) (Cell Host and Microbe). Hear from multiple scientists who study drivers of cancer and discover how these genes and proteins might be targeted to prevent cancer’s spread (16:26) (from Cancer Cell). Plus, sample a selection of the hottest new papers from Cell Press (24:15).
How fine-tuning of transcription factor activity may open up new avenues for disease treatment, with Mark Leid (0:00) (Trends in Pharmacological Sciences). How the millions of species of gut bacteria can communicate with one another, with Simon Carding (11:28) (Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (16:45).
How gene control can be fine-tuned to coordinate growth during times of feast or famine, with Ryan Baugh (0:00) (from Cell Reports). How the lipid membrane of the tuberculosis bacterium provides clues for fighting this deadly disease, with Mamadou Daffé (6:55) (from Chemistry and Biology). Plus, sample a selection of the hottest new papers from Cell Press (17:20).
How a tiny fish can model big human diseases, with Leonard Zon (0:00) (special issue of Trends in Cell Biology). How dietary fat may alter your timing, with Paolo Sassone-Corsi (10:35) (from Cell). How to make a stem cell grow up quick, with Lorenz Studer (17:38) (from Cell Stem Cell). Plus, sample a selection of the hottest new papers from Cell Press (26:10).
How manipulation of endogenous marijuana-like chemicals might help treat anxiety disorders, with Andrew Holmes (0:00) (from Trends in Pharmacological Sciences). What prevents distinct species from interbreeding, with Axel Imhof (11:15) (from Developmental Cell). Plus, sample a selection of the hottest new papers from Cell Press (18:45).
How blocking tau protein tangles in the brain may combat neurodegeneration, with David Holtzman (0:00) (from Neuron). How the US government is betting big on neuroscience research, with Cori Bargmann (6:42) (from Cell). How a common virus is linked to several kinds of cancers, with Henri-Jacques Delecluse (16:50) (from Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (21:20).
What makes a memory, with Jonathan Crystal (0:00) (Special issue on memory from Current Biology). The birth of the Protein Data Bank, which has facilitated structural biology research around the globe, with Helen Berman (7:55) (20th anniversary special edition of Structure). How the evolutionary strategies of bacteria are influenced by the surfaces that they live on, with Dave van Ditmarsch and Joao Xavier (14:35) (Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (24:00).
How drug treatment may be able to help the body’s own immune system to defeat cancerous tumors, with Ira Mellman (0:00) (Immunity special issue on cancer immunotherapy). How improved understanding of the immune system's reaction to food would help reduce the epidemic of food allergies, with Hugh Sampson (13:45) (Trends in Immunology). Plus, sample a selection of the hottest new papers from Cell Press (25:27).
How energy-burning brown fat could possibly be used to treat obesity, with Antonio Vidal-Puig (0:00) (Trends in Pharmacological Sciences). How sleeping muscle stem cells might be awakened to fight aging, with Thomas Rando (9:42) (Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (19:30)
How microbes use various tricks to evade the immune system over time, with Christopher Sassetti (0:00) (Cell Host & Microbe). How the aggregation of proteins can sometimes be helpful to an organism, with Amy Gladfelter (8:15) (Developmental Cell). Plus, sample a selection of the hottest new papers from Cell Press (17:23).
How little we know about what our ancestors really ate for dinner, with Richard Wrangham (0:00). How the field of neuroscience has changed over the past 25 years, with Eric Kandel (8:17). How countries are working to shape economic and social policies on biotechnology, even as the field is rapidly growing, with Jim Philp (15:15). Plus, sample a selection of the hottest new papers from Cell Press (21:43).
How epigenetics has changed the way that scientists think about heredity, with Nathan Springer (0:00). How researchers are using a trick of light to understand the behavior of single cells, with Christof Taxis (10:22). Plus, sample a selection of the hottest new papers from Cell Press (16:05).
How understanding of the cell nucleus has evolved over time, with Tom Misteli (0:00). How developments in biotechnology have spurred entire new industries over the last thirty years, with Bo Mattiasson(11:22). Plus, sample a selection of the hottest new papers from Cell Press (17:06).
How understanding neural control of appetite might help fight obesity, with Tamas Horvath (0:00) Trends in Neurosciences. How elemental design principles can provide insight into biological processing, with Wendell Lim (8:42) Molecular Cell. Plus, sample a selection of the hottest new papers from Cell Press (16:12).
In this month's Cell Podcast, we learn how llamas have helped the study of G protein-coupled receptors, with Brian Kobilka (0:00) (Trends in Pharmacological Sciences), how to teach an old genetic analysis test a cool new trick, with Trey Ideker (10:50) (Cell Reports). Plus, sample a selection of the hottest new papers from Cell Press (17:00).
In this month's Cell Podcast, we learn how designer techniques from synthetic biology are influencing the field of cell biology, with Wendell A. Lim and Wallace F. Marshall (0:00) (Trends in Cell Biology), how changes in specific genes triggered the evolution from fish fins to the limbs of vertebrates, with José Luis Gómez-Skarmeta and Fernando Casares (6:41) (Developmental Cell). Plus, sample a selection of the hottest new papers from Cell Press (13:42).
In this month's Cell Podcast, we learn about how stem cells from the testes may preserve fertility in young male cancer patients, with Kyle Orwig (0:00) (Cell Stem Cell), the crucial role of TGF-β in the spread of colorectal cancer, with Eduard Batlle (8:30) (Cancer Cell). Plus, sample a selection of the hottest new papers from Cell Press (15:15).
In this month's Cell Podcast, we learn about Developing drugs to tackle Schizophrenia, using rodents models, with Mark Geyer (0:00) (October issue of Trends in Pharmacological Sciences), the role of next-gen sequencing in vaccine design, with Andrew Lloyd (8.50) (September issue of Trends in Biotechnology), interpreting the genome to pinpoint mutations in an inherited blood disorder, with Vijay Sankaran (17.38), Plus, sample a selection of the hottest new papers from Cell Press (23.08).
In this month's Cell Podcast, we learn about altering neuronal circuits depending on the environment, with Cori Bargmann (0:00) (Forthcoming Cell Symposia on Neuromodulatory Mechanisms), the role of mitochondria in diabetes, with Orian Shirihai (8:30) (Trends in Endocrinology and Metabolism September Special issue), and how the power of the placebo has evolved over time, with Nicholas Humphrey (15:05) (Current Biology September Special issue). Plus, sample a selection of the hottest new papers from Cell Press (25:20).
In this month's Cell Podcast, we cover the role of "friendly" gut bacteria in immune system defense, with Eric Pamer (0:00) (Trends in Immunology Online Now), a potential treatment targeting a cannabinoid receptor that seems to reign in appetite and reduce body fat, with George Kunos (8:20) (Cell Metabolism August issue), and the history and significance of mirror neurons, which fire when watching others' actions, with Marco Iacoboni (15:00) (Current Biology 21st Anniversary Celebration). Plus, sample a selection of the hottest new papers from Cell Press (22:07).
In this month's Cell Podcast, we cover how a scorpion venom-derived peptide might be used to treat glioma, with Harald Sontheimer (0:00) (Trends in Neurosciences June issue), visualizing the immune system in 3D to monitor inflammation in a whole organism, with Eric Skaar (7:58) (Cell Host and Microbe June 14 issue), and understanding how mothers tolerate the "alien within" during pregnancy, with Alexander Rudensky (14:31) (Cell July 6 issue). Plus, sample a selection of the hottest new papers from Cell Press (22:01).
In this month's Cell Podcast, we learn how neglected tropical diseases such as river blindness also have an underappreciated burden of mental health issues, with David Molyneux (0:00) (Trends in Parasitology May Issue), a new approach to treating persistent neuropathic pain using embryonic cell transplants, with Allan Basbaum (7:26) (Neuron May 24 Issue), and why we're celebrating two milestone birthdays in the stem cell field - 10 years of the ISSCR and 5 years of Cell Stem Cell, with Len Zon (14.20) (Cell Stem Cell Anniversary Issue). Plus, sample a selection of the hottest new papers from Cell Press (22:07).
In this month's Cell Podcast, we learn how plant defenses have shaped the fussy dining habits of insects, with Anurag Agrawal (0:00) (Trends in Plant Science Special Issue), why after twenty years, John O’Shea is still excited about cytokine signaling, (8:34) (Immunity Special Feature on the JAK-STAT pathway), and why being the right size is a matter of life or death for free-falling rodents, with Andrew Spence (15:15) (Current Biology Special Issue on Size Control). Plus, sample a selection of the hottest new papers from Cell Press (20:46).
In this month's Cell Podcast, we learn about how cells sense when they're feeling sluggish and need to refuel, with Claudio De Virgilio (0:00) (Bonfils et al. and Han et al.), a eureka moment in the lab becomes a new therapy in the clinic, with Laurie Glimcher (7:16) (Cell Special Issue on Human Diseases), and a shape-shifting enzyme busts blood clots, with James Whisstock (14:12) (Law et al.). Plus, sample a selection of the hottest new papers from Cell Press (22:25).
In this month's Cell Podcast, we learn about the promises and potential perils of synthetic biology, with Vincent Martin and Tania Bubela (0:00), why sirtuin inhibitors may bring a cure for CML a step closer, with Ravi Bhatia (9:44), and how platelet producing cells avoid the pinch to become polyploid, with Diane Krause (14:56). Plus, sample a selection of the hottest new papers from Cell Press (23:14).
In this month's Cell Podcast, we learn how a lucky find in an obscure dental journal inspired the development of ibuprofen, with the drug’s discoverer Stewart Adams (0:00), why we’re still struggling to combat malaria, with Kip Guy (9:29), and how evolution finds multiple routes to the same phenotype, with Chris Marx (18:05). Plus, sample a selection of the hottest new papers from Cell Press (24:44).
In this month's Cell Podcast, we learn about why structural biologists need no longer fear the membrane, with Doug Rees (Tirado-Lee et al. and Special Reviews Collection) (0:00), why epithelial biology is going 3D (glasses not included), with Ian Macara (McCaffrey et al. and Special Issue of Trends in Cell Biology) (8:42), and how sperm cells get their epigenetic message across, with Philippe Collas (Lindemann et al.) (13:54).
In this month's Cell Podcast, we learn about what mouse whiskers can tell us about how we perceive the world through touch, with David Kleinfield (0:00), how to stimulate heart repair by rewinding cardiomyocyte differentiation, with Thomas Braun (8:20), and a new strategy to stay one step ahead of the influenza virus, with Patrick Wilson (13:58).
In this month's Cell Podcast, we learn how to tune the intestinal immune system with microbial cocktails, with Dan Littman (0:00) (Sczesnak et al.), why there's more to DNA methylation than CpG islands in the hematopoietic system, with Greg Hannon (9:35) (Hodges et al.), where modern humans interbred with their ancient hominin cousins on the journey out of Africa, with Mark Stoneking (15:51) (Reich et al.), and whether humans are better team players than chimpanzees, with Daniel Haun (21:15) (Rekers et al.).
In this month's Cell Podcast, we learn about the challenges of applying genetics to human mental health, with Trevor Robbins (0:00), a game of vesicular cat and mouse between bacterial lipids and the immune system, with Michael Brenner (10:48), and the shifting identities of stem-like cells in breast cancer, with Eric Lander (17:18).
In this month's Cell Podcast, we learn about how SUMOlyation wrestles hedgehog signaling into the right location during endocrine development, with Holly Ingraham (0:00), how neural stem cell progenitors are protected during starvation, from Alex Gould (12:01), and what's required in AML to make a cell susceptible to oncogenic transformation, explains Keith Humphries (17:48).
In this month's Cell Podcast, we learn about a lysosomal thread linking synucleinopathies, with Dimitri Krainc (0:00) (Mazzulli et al.), the genetics of human height, with Valerie Cormier-Daire (8:00), and polar bears: getting in touch with their surprising origins, with Beth Shapiro (14:31).
In this month's Cell Podcast, we learn about getting neural stem cells out of the lab and into the clinic, with Sally Temple (0:00), an important role for rare copy number variations in autism, with Matthew State and Michael Wigler (8:30), the dangers of midnight feasts for fruit fly fertility, with Amita Sehgal (18:04), and fitness costs and crosstalk in the evolution of host defense pathways, with Ruslan Medzhitov (24:32).
In this month's Cell Podcast, we learn about ape droppings and the origins of malaria, with Julian Rayner (0:00), A next-gen sequencing technique to study high-speed gene expression, with W. Lee Kraus (9:35), and Tracing the evolution of signaling pathways in plants, with Alistair Hetherington (15:56).
In this month's Cell Podcast, we learn about how HIV hides in hempatopoietic stem cells (0:00), combating tuberculosis drug resistance (7:25), and suppressing tumors with a protein isomerase (13:41).
Cellular "coin-flipping;" Jim Collins explains how cells make decisions (0:00), the vicious cycle of treating drug addiction as a criminal behavior, instead of a medical condition (8:23), and how small molecules can help uncover signaling crosstalk, when genetic strategies fail (16:56).
Engineering cyanobacteria to a make a profit—not just biofuels (0:00), why breast cancers often metastasize to the bone (11:03), and EPO's surprising anti-inflammatory properties (17:15).
Hunting down biomarkers for Alzheimer's diease (0:30), modeling Progeria with iPS cells (10:13), and how yeast spare their daughter cells from toxic aging factors (16:52).
Hear about filling in the gaps of the 1000 genomes project (0:50), learn about tracking down an elusive culprit of inherited diseases. (10:05), discover how chromatin-modifying enzymes orchestrate skin development (18:22).
Learn how skeletal stem cells are key to improving osteoporosis treatment regimes (1.00), discover what a new pain gene has in common with Hungarian composer Franz Liszt (10.33), and hear insights from new metabolomics analysis of the tuberculosis pathogen (17:51).
Hear how human genetics is transforming neuroscience (0:55), understand how sphingolipids are key signaling molecules during development(16:34), and learn about a critical interaction in noncanonical Wnt signaling (25:34).
Learn how a sodium-calcium exchanger helps humans see in the dark (0:42), understand why one microRNA is critical for stopping autoimmune attacks in mice (7:43), and hear how light pollution is coercing some songbirds to cheat on their mates (13:21).
Hear about a strategy to reverse the muscle wasting that accompanies cancer (00:55), learn about a kinase that is a key regulator of gut regeneration (07:42), and find out about new insights into brain metabolism (14:02).
Learn how matrix metalloproteinases are involved in Huntington's disease (00:50), hear about the functions of telomere DNA sequences (9:46), and learn how the lipid diacyl glycerol helps to fight bacterial infection (16:13).
Learn about a key step in the reprogramming of fibroblasts to induced pluripotent stem cells (00:49), hear about an unexpected connection between Alzheimer's disease and autophagy (10:44) and learn how our DNA stays neatly folded (18:44).
Hear how the influenza virus mobilizes immune cells, learn about the peripatetic habits of dendritic cells, and hear about the structure of a large transcription factor called SAGA.
Hear about two new inhibitors that block the toxin ricin, keep up to date with the latest research news about type 1 diabetes (10:13), and learn how brown fat can keep you thin (16.40).
Hear how social behaviors are connected to neural circuitry (0:54), learn how optogenetics tools track the activity of neuronal populations in animals (12:38), and learn about ovarian cancer cells that are addicted to the ERBB3 oncogene.
Learn about the earliest journeys of our ancestors revealed by archaeogenetics (0:50), a versatile transcription elongation factor with several key functions in the cell (11:12) and an oncoprotein and its many partners, which are involved in leukemia (16:21).
Learn about daughter yeast cells that retain the fountain of youth (0:48), how a singing contest helps mosquitoes find the ideal mate (8:22), and a nuclear receptor that keeps fruit flies slim (13:51).
Dr. Emilie Marcus talks with two of this year's Nobel Laureates, Dr. Elizabeth Blackburn and Dr. Venki Ramakrishnan about their groundbreaking research on telomeres (1:04) and the ribosome (14:29), respectively. Learn about the connection between two major molecular players in Alzheimer's disease (29:15).
Learn about two new studies identifying a protein complex that helps with intracellular membrane trafficking (start 0:47) and hear how a key cell-cycle regulator that is overexpressed in breast cancer cells is itself regulated (9:35).
Learn about a clever way that the influenza virus outwits the host immune system (start 0:47), hear why our ancestors abandoned hunting and fishing and took up farming instead (8:55), and discover what fruit fly memories are really made of (start 13:05).
Unravel the enduring mysteries of why we sleep (start 0:52), learn about the regulation of clock genes and circadian rhythms (9:45), and hear about a study that identifies rare variants associated with breast cancer risk (start 15:42).
Learn about an X chromosome variant that protects against the progression of AIDS (start 0:50), hear about a microRNA that is decreased in both normal and cancer stem cells (start 8:08), and learn about migrating cells in the worm embryo (start 17:08).
Learn how cancer cells evade detection by macrophages (start 0:46), hear about a screen for genes that keep the genome stable (start 10:37) and new therapeutic targets for treating tuberculosis (start 16:12).
Learn how stem cells can repair damaged lung tissue (start 1:04), how delivery of a microRNA to liver tumors in mice halts tumor growth (start 10:25), and why RNA could be a useful drug target (start 18:41).
Learn how bladder epithelium regenerates after infection (0:53) and which amino acids are involved in developing insulin resistance (9:50). Hear the latest news about regulatory T cells (14:37).
Learn about a microRNA that confers robustness on the pathways regulating fly development (start 0:50), the cytokine interleukin-1 which acts as a key player in the production of Th17 cells (start 10:23) and using stem cell therapy to treat heart disease (start 15:22).
Learn about an unexpected pro-apoptotic role for the retinoblastoma tumor suppressor (start 1:22), a cytoplasmic filter in neurons (start 9:35) and an intricate molecular interaction that underpins the oxidative stress response in yeast (start 17:13).
Hear about a new study that reveals how human melanoma cells elude signals from a key growth control pathway, how to reprogram cells back to a pluripotent state, and how variations in human genes possibly contribute to human evolution.
Hear about a new study that reveals how aging cells end up with leaky nuclei and how the glossy leaves of crop plants may help to counteract global warming. And stay tuned to hear about a study in Cell Metabolism that explains how the body keeps cholesterol synthesis in check.
Hear about "TRAP," a new technique for looking at gene expression in the brain and the curious classification of the Hawaiian honeyeater. You'll also learn about a large-scale screen for mutations involved in Diamond-Blackfan anemia.
Hear about a lipid hormone made by fat that can keep you thin, and learn from the immunologist who discovered dendritic cells how these enigmatic cells can help to make better vaccines, and stay tuned to discover how the human brain controls responses to fearful memories and the implications for treating post-traumatic stress disorder.
Hear about a study that brings us a step closer to treating neurological diseases with stem cell therapy and a metabolic hormone that conserves energy during starvation. Learn more about the inner workings of a calcium ion sensor. Finally, stay tuned for our quarterly roundup of exciting research highlights published in the Cell Press family of journals.
Hear about reprogramming the body's immune B cells and also what makes brain tumors so deadly. Discover more about the insidious pathogen that causes tuberculosis ...and don't forget our quarterly round-up of exciting research highlights published in the Cell Press family of journals.
Dr Ben Barres talks about about a molecule in the immune system that is important for eliminating synapses in the nervous system and we hear about a cluster of exciting research including a gene that is important for pigmentation differences in stickleback fish and humans and a protein that controls master regulators of gene expression called microRNAs
Includes interviews with Dr Jim Collins about how several common antibiotics kill bacteria by generating lethal hydroxyl radicals and with Dr Rudi Grosschedl on how gene regulation can be coordinated by interactions between chromosomes.
Includes interviews with Dr Jonathan Weissman about new technologies that are changing the research enterprise, Dr John Kuriyan about how kinases keep themselves switched off until they are needed, and Dr Wolf-Dieter Schubert about coaxing a human pathogen to invade a mouse.
Includes interviews with Dr Francis Collins on the international mouse knockout program, Dr David Fisher on the role of p53 in tanning, and Dr Greg Hannon on pi RNAs silence transposons in the fly genome.
A look back at 2006, featuring interviews with two of this year's Nobel Laureates, Dr Craig Mello and Dr Roger Kornberg, as well as Dr Paul Nurse, sharing his views on how the results of the recent midterm elections may influence biomedical research funding in the United States