Inside the GENOME: Recent Episodes
Myriad Oncology
Hosted by Dr. Thomas Slavin, Chief Medical Officer for Myriad Genetics, Inside the GENOME will be exploring the world of cutting-edge cancer genetics with 2-3 episodes per month. Dr. Slavin will interview those on the front lines of cancer, and those advancing the science of cancer prevention, diagnosis, and treatment. Inside the GENOME - Genetics, Oncology and Me.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
In this episode Dr. Slavin sits down with Chris Jacobs, Founder and former-CEO of Gateway genomics to discuss exciting advances for parents to be.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Taylor Kane shares her family’s story from her father being affected by ALD when she was a child and what that means for her and her future as a carrier of this condition
Ashley Pantier has two children with SMA and shares her family’s journey and how carrier screening gave them the knowledge they needed in diagnosing her children with SMA
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Websites Referenced:
https://pubmed.ncbi.nlm.nih.gov/25503495/
https://pubmed.ncbi.nlm.nih.gov/11746004/
https://pubmed.ncbi.nlm.nih.gov/34459979/
https://www.nature.com/articles/s41431-018-0285-1
https://pubmed.ncbi.nlm.nih.gov/31553108/
https://pubmed.ncbi.nlm.nih.gov/29158769/
https://pubmed.ncbi.nlm.nih.gov/33420344/
https://www.clinicalgenome.org/genomeconnect/for-patients-genomeconnect/
https://uclawreview.org/2021/04/06/medical-malpractice-the-custom-based-standard-vs-the-reasonable-physician-standard/
https://pubmed.ncbi.nlm.nih.gov/30578420/.
https://www.oncotarget.com/article/26501/
https://journals.sagepub.com/doi/pdf/10.1177/1073110520916994
https://pubmed.ncbi.nlm.nih.gov/32154515/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Non-profit organization for the ovarian cancer community and clinical trials: https://www.clearityfoundation.org/
Clinical Trials: https://forms.clearityfoundation.org/find-clinical-trials/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Dr. Ifey Stitt is a board certified OB-GYN dedicated to women's health, with special interest in genetics and education. She practices in Annapolis, Maryland and is affiliated with Luminis health where she serves as medical director for her group.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Dr. Mattie Crutchfield. They discuss her journey from considering genetic testing to learning she is a PALB2 mutation carrier and how she is taking action to reduce her cancer risk.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
References for this episode:
https://fenwayhealth.org/the-fenway-institute/education/the-national-lgbtia-health-education-center/
https://transcare.ucsf.edu/guidelines
BRCA care: https://journals.lww.com/greenjournal/Fulltext/2021/12000/Creating_Breast_and_Gynecologic_Cancer_Guidelines.16.aspx#:~:text=As%20breast%20surgery%20often%20leaves,rather%20than%20traditional%20chest%20masculinization.
Free course about teaching LGBTQ+: Healthhttps://mededucation.stanford.edu/courses/teaching-lgbtq-health/
https://fenwayhealth.org/the-fenway-institute/education/advancing-excellence-in-sexual-and-gender-minority-health/train-the-trainer-course/
https://www.kff.org/other/issue-brief/youth-access-to-gender-affirming-care-the-federal-and-state-policy-landscape/
https://www.aclu.org/legislation-affecting-lgbtq-rights-across-country
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
References for this episode:
Kerlilowske reference: JCO 2010. https://pubmed.ncbi.nlm.nih.gov/20644098/
Other suggested articles from Dr. Pederson: Automated Quantitative Measures of Terminal Duct Lobular Unit Involution and Breast Cancer Risk https://pubmed.ncbi.nlm.nih.gov/32917665/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit https://myriad.com/live/ for a list of dates, times, and subjects.
References for this episode:
Genome web article: https://www.genomeweb.com/sequencing/early-cancer-detection-li-fraumeni-syndrome-patients-enabled-liquid-biopsy-test
Abstract: https://acmg.planion.com/Web.User/AbstractDet?ACCOUNT=ACMG&CONF=AM22&ssoOverride=OFF&ABSID=12124
CHARM consortium https://charmconsortium.ca/
NCCN Guidelines: https://www.nccn.org/professionals/physician_gls/pdf/genetics_bop.pdf
Tumor-Based Genetic Testing and Familial Cancer Risk https://pubmed.ncbi.nlm.nih.gov/31570381
https://liftupstudy.org/
https://ascopubs.org/doi/abs/10.1200/JCO.2020.38.15_suppl.1514
In this episode Dr. Slavin welcomes Dr. Judy Garber, Professor of Medicine at Harvard Medical School, Chief of Division of Cancer Genetics and Prevention at the Dana Farber Institute, and Susan F. Smith Chair. Together, they discuss the OlympiA study and outcomes that have influenced industry guidelines.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
References for this episode:
https://genesight.com/for-clinicians/clinical-studies/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
References for this episode:
https://ocrahope.org/2021/05/highlights-2021-virtual-annual-meeting-of-sgo/https://www.cancernetwork.com/conference/sgo
List of accepted abstracts from 23rd Annual American Society of Breast Surgeons https://www.breastsurgeons.org/meeting/2022/https://www.breastsurgeons.org/meeting/2022/docs/2022_Official_Proceedings_ASBrS.pdf
Kurian et al paper. https://jamanetwork.com/journals/jama/article-abstract/2600457
Highlights From the Miami Breast Cancer Conference 2022— Co-chair Debu Tripathy, MD, provides an overview of the studies discussed at the meetinghttps://www.medpagetoday.com/meetingcoverage/mbcc-video-pearls/97669Abstracts:https://www.cancernetwork.com/journals/mbcc-suppl/38th-annual-miami-breast-cancer-conference-abstracts-miami-breast-cancer-conference-abstract-supplements
It has been more than twenty years since the collapse of the World Trade Center on September 11th, 2001. Dr. Slavin discusses Myriad Genetics’ company-wide involvement in the effort to help identify victims of the tragedy with John Ryan, Sr. VP of Operations, Women’s Health and Oncology, and Benoît Leclair, Program Director of Quality Assurance and Regulatory Affairs.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
References for this episode:
https://education.asco.org/coursecollection/genetics-and-genomics
COH-Registration now openhttps://www.cityofhope.org/education/health-professional-education/cancer-genomics-education-program/intensive-course-in-cancer-risk-assessment-overview
https://online.stanford.edu/programs/genetics-and-genomics-program
https://www.nurseportfolio.org/
Medical Breast Training Program - Mayo, Cleveland Clinic and Women's College of Toronto : https://ce.mayo.edu/online-education/content/medical-breast-training-program-all-sessions#group-tabs-node-course-default2
https://www.ons.org/learning-libraries/precision-oncology
Diversification of Nurse Practitioner Practice: Genetic Cancer Risk Assessmenthttps://www.sciencedirect.com/science/article/pii/S1555415520301276?via%3Dihub
https://www.duq.edu/academics/schools/nursing/faculty/grants/genomic-competencies-for-nurses-from-theory-to-application-an-online-course#:~:text=This%20professional%20development%20opportunity%20is,year%2C%20each%20spring%20and%20fall.
https://myriad-oncology.com/continuing-education-webinars/
The Myriad Oncology RMS team also leads a series via webinar for GC's and Nurses "Evolving Strategies in Hereditary Cancer". These can be viewed live by invitation. contact your local RMS team to get on that invite list. Also these are available on demand after the live presentation at our webpage https://myriad-oncology.com/continuing-education-webinars/
https://www.gimjournal.org/multimedia/audio#:~:text=GenePod%20is%20the%20podcast%20from,content%20from%20this%20leading%20journal.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
References for this episode:
Open Access: Addressing Reproductive Healthcare Disparities through Equitable Carrier Screening: Medical Racism and Genetic Discrimination in United States’ History Highlights the Needs for Change in Obstetrical Genetics Care https://www.mdpi.com/2075-4698/12/2/33
ACMG poster. eP336: A tale of two HBs: DNA Sequencing and hemoglobin electrophoresis. https://www.gimjournal.org/article/S1098-3600(22)00388-4/fulltext
The Evolving Role of Next-Generation Sequencing in Screening and Diagnosis of Hemoglobinopathies. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353275/
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin speaks with breast surgeon Dr. Allison DiPasquale, Director of Breast Oncology at Medical City Dallas and Board President of the Susan G. Komen Dallas County Chapter. They discuss the role of genetics in breast cancer treatment and prevention.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Links referenced and shared in this episode:
https://www.nccn.org/professionals/physician_gls/pdf/kidney.pdf
Bratslavsky et al. Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement. Cancer. 2021 Nov 1;127(21):3957-3966. doi: 10.1002/cncr.33679. Epub 2021 Aug 3. https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.33679
Carlo MI, Mukherjee S, Mandelker D, et al. Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma. JAMA Oncol. 2018;4(9):1228-1235. doi:10.1001/jamaoncol.2018.1986 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584283/
Cryoablation versus Partial Nephrectomy for Clinical Stage T1 Renal Masses: A Systematic Review and Meta-Analysis, https://pubmed.ncbi.nlm.nih.gov/30854132/
https://pubmed.ncbi.nlm.nih.gov/34882627/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930334/
https://ascopubs.org/doi/abs/10.1200/PO.20.00118
In this episode, Dr. Slavin hosts Dr. Tin-Yun Tang, a current hematology and oncology fellow at MD Anderson Cancer Center. Together, they discuss what programs and training can look like for physicians interested in genetics research and Dr. Tang’s efforts in genomic research during his combined internal medicine and clinical genetics and genomics residency at Case Western Reserve University.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Leigha Senter-Jamieson, MS, CGC, to the podcast. As an Associate Professor of Internal Medicine, Associate Director of the Division of Human Genetics, and the Ohio State University Genetic Counseling Graduate Program Associate Director she discusses hereditary testing and offers her unique insight into the emerging role of genetic counselors in tumor testing.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode, Dr. Slavin welcomes Dr. Todd Cohen, Vice President of Medical Affairs for the Myriad Urology department. Dr. Cohen formerly practiced with Hawes Urology before pursuing an academic role as the Assistant Chairman of Urology at Ohio State University. He then co-founded Piedmont Urology in Charlotte, NC before forming Carolina Urology Partners, a merging of nine urology groups, where he acted as co-CEO, then CEO. Myriad Genetics welcomed Dr. Cohen in his leadership role in March of 2019. Dr. Cohen brings his many years of expertise to the discussion regarding genomics, the role of gene expression assays, and the treatment of prostate cancer.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Additional resources cited in this episode:
Hu et al NEJM - A population based study of genes previously implicated in Breast Cancer 2021. https://www.nejm.org/doi/pdf/10.1056/NEJMoa2005936
Palmer et al. JNCI paper - Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women. https://pubmed.ncbi.nlm.nih.gov/32427313/
Antoniou et al NEJM - Breast caner risk in families with mutations in PALB2 2014. https://pubmed.ncbi.nlm.nih.gov/25099575/
Yang et al 2020 PALB2 paper Dr. Couch referenced
https://pubmed.ncbi.nlm.nih.gov/31841383/
BCAC study - NEJM 2021 https://www.nejm.org/doi/full/10.1056/nejmoa1913948
Narod editorial to these two papers - CARRIERS and BCAC. https://www.nejm.org/doi/full/10.1056/NEJMe2035083?query=recirc_curatedRelated_article
BCAC Study paper titled: Breast Cancer Risk Genes - Association in More than 113,000 Women CARRIERS study is titled - A Population Based Study of Genes Previously Implicated in Breast Cancer
In this episode, Dr. Slavin welcomes medical oncologist and researcher, Adam Brufsky, MD, PhD, FACP. He is a professor of medicine at the University of Pittsburgh School of Medicine and co-director of the Comprehensive Breast Cancer Center. Dr. Brufsky has been an innovator involved with breast cancer research for many years. Together, they discuss breast cancer gene expression assays and the role it plays in treating breast cancer.
In this episode of Inside the Genome, Dr. Slavin talks with Dr. Karen Hurley. Dr. Hurley is a licensed clinical psychologist in the Center for Adult Behavioral Health at the Cleveland Clinic in Ohio. She has given numerous presentations on patients’ psychosocial situations as they experience the genetic testing process.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Many studies were referenced in this episode, please see links below:
Yanes T, et al. Clinical applications of Polygenic breast cancer risk: a critical review and perspective of an emerging field. Breast Cancer Res 22, 21 (2020). https://pubmed.ncbi.nlm.nih.gov/32066492/
Mars et al study link: https://www.nature.com/articles/s41467-020-19966-5
Rosner et al study: https://cebp.aacrjournals.org/content/cebp/early/2020/12/04/1055-9965.EPI-20-0900.full.pdf
Lakeman et al study: https://www.nature.com/articles/s41436-020-0884-4
Barnes et al study: https://www.nature.com/articles/s41436-020-0862-x
https://www.nature.com/articles/ng.3841
https://pubmed.ncbi.nlm.nih.gov/25862352/
This is the study where the chart comes from : https://pubmed.ncbi.nlm.nih.gov/32620971/
Here is the abstract from ASCO about ancestrally unbiased breast cancer (BC) risk assessment. Dr. Pederson also presented this material during the meeting. https://meetinglibrary.asco.org/record/197017/abstract
Here is the Tischkowitz paper Dr. Slavin was discussing: https://www.acmg.net/PDFLibrary/41436_2021_1151_OnlinePDF.pdf
Gallagher paper (chart was from this paper) https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2767768
Yanes T, et al. Women's responses and understanding of polygenic breast cancer risk information. Fam Cancer. 2020 Oct;19(4):297-306. https://pubmed.ncbi.nlm.nih.gov/32430685/
https://cancerpreventionresearch.aacrjournals.org/content/early/2020/10/23/1940-6207.CAPR-20-0154?versioned=true
Hughes et al paper where data from chart is derived: https://ascopubs.org/doi/full/10.1200/PO.20.00246
Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score https://ascopubs.org/doi/full/10.1200/JCO.20.01992
Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast Cancer https://www.nejm.org/doi/full/10.1056/NEJMoa2105215
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
Myriad Oncology Live episodes are recordings of an open-forum webinar hosted by Dr. Thomas Slavin. The opinions and views expressed in this recording do not necessarily represent those of Myriad Genetics or its affiliates. To participate in a future recording, visit myriad-oncology.com/myriad-oncology-live for a list of dates, times, and subjects.
In this episode of Inside the Genome, Dr. Slavin is joined by three-time cancer survivor, Annie Parker. They discuss how early genetic testing had an impact on her journey through survivorship.
About Our Guest: Annie Parker was one of the first women to be tested for BRCA mutations after experiencing cancer at an early age. She is an advocate for women’s health and runs the Annie Parker Foundation.
In this episode of Inside the GENOME, Dr. Slavin sits down with William J. Harb, MD, FACS, FASCRS. They discuss the importance of raising awareness for colorectal cancer.
About Our Guest:
Dr. William Harb is a board-certified colorectal surgeon, specializing in the treatment of diseases of the colon and rectum. Through his dedication and national recognition with hereditary colorectal cancer, genetic testing has become an integral part of his practice. Dr. Harb works at the Colorectal Center in Nashville, Tennessee. https://thecolorectalcenter.com/
In this episode of Inside the GENOME, Dr. Slavin sits down with Nicole Lambert, President of Myriad Genetics. They discuss her background as a genetic counselor and how she came to her role as President of Myriad, her personal story with her own genetics and risk assessment which led to her decision to undergo preventative surgery, and how Myriad is at the forefront of breast cancer risk assessment.
In this episode of Inside the GENOME, Dr. Slavin sits down with Elisabeth King, RN, FNP, AGN, AOCNP of City of Hope. They discuss the differences between training and scope among genetics professionals, and how she came into her role as a genetics provider.
About Our Guest:
Elisabeth King, is an Advanced Practice Provider with specialized training in genetics and is the Executive Director of Genomics and Precision Medicine at City of Hope.
https://www.cityofhope.org/elisabeth-king
About This Episode
Dr. Holly Pederson is the director of the Medical Breast services in the breast center at the Cleveland Clinic. She is an Associate Professor at the Cleveland Clinic Lerner College of Medicine.
She sits down with Dr. Slavin to discuss a newly emerging tool within hereditary cancer genetics: polygenic risk scores.
In this episode, Dr. Slavin sits down with Vincent Chung, MD, City of Hope, to discuss his position at City of Hope as a pancreatic cancer medical oncology expert, coronavirus affects on cancer care, and the role genetics plays for determining certain pancreatic cancer treatments.
About Our Guest:
Vincent Chung, M.D., is a medical oncologist specializing in pancreatic cancer and other gastrointestinal cancers. He runs many clinical trials with the hopes to improve the lives of patients affected by these cancers.
In this episode, Dr. Slavin sits down with Michael Hall, MD, Fox Chace Cancer Center, to discuss how he got to where he is today, his department of clinical genetics, and how he thinks COVID-19 will change the world of cancer genetics.
About Our Guest:
Dr. Michael Hall is Chair and Professor of the Department of Clinical Genetics at Fox Chase Cancer Center. He is a physician-scientist, medical oncologist, and an expert in gastrointestinal cancers, particularly those cause by hereditary syndromes.
In this episode, Dr. Slavin joined by Shelly Cummings, MS, CGC Director of Myriad Oncology Medical Affairs, speak with Sue Friedman - Founder and Executive Director of the hereditary testing patient advocacy group, Facing Our Risk of Cancer Empowered - F.O.R.C.E. They discuss how FORCE was created, how it has been affected by COVID-19, and what initiatives are currently in the works.
About F.O.R.C.E.
Facing Our Risk Of Cancer Empowered - F.O.R.C.E. advocates for families facing hereditary breast and ovarian cancer in areas such as access to care, research funding, insurance, and privacy. Learn more here: https://www.facingourrisk.org/
In this episode, Dr. Slavin sits down with David C. Weintritt, MD, FACS, to discuss how his practice has been able to adapt patient visits to a telehealth format and how he is navigating the current environment to continue providing a high standard of patient care remotely.
About Our Guest:
David C. Weintritt, MD, FACS is Assistant Clinical Professor, Department of Surgery, GW Medical Faculty Associates, Founder, National Breast Center and Foundation, and Director, Inova Mt. Vernon Breast Program.
In this episode, Dr. Slavin speaks with Dr. Tuya Pal about the opportunities and challenges she has seen from the COVID-19 pandemic surrounding clinical cancer care and research.
About Our Guest:
Dr. Tuya Pal, MD is Associate Director for Cancer Health Disparities and Ingram Associate Professor of Cancer Research at Vanderbilt-Ingram Cancer Center. She is a nationally recognized physician-scientist expert in hereditary cancer genetics. https://www.vicc.org/member/tuya-pal
Welcome to the Inside the GENOME podcast with Dr. Thomas Slavin, Sr. Vice President of Medical Affairs for Myriad Oncology. In this episode Dr. Slavin discusses the intentions behind creating this casual yet educational podcast about cancer genetics. Enjoy!
In this episode, Dr. Slavin joined by Shelly Cummings, MS, CGC Director of Myriad Oncology Medical Affairs, speak with Jennifer Klemp - PhD, MPH, MA Associate Professor of Medicine in the Division of Clinical Oncology at the University of Kansas Cancer Center about her experience with telegenetics and the effect that she has seen from the COVID-19 pandemic.
About Our Guest:
Jennifer Klemp, PhD, MPH, MA Associate Professor of Medicine in the Division of Clinical Oncology and Director of Cancer Survivorship, Co-Program Leader for Cancer Prevention and Control at the University of Kansas Cancer Center. She is the founder and CEO of Cancer Survivorship Training, Inc., an eLearning company supporting healthcare professionals, and is Principal of Cancer Resource Partners, LLC.