RheumMadness Podcast: Recent Episodes
RheumMadness
The RheumMadness podcast is part of a rheumatology learning initiative sponsored by the Rheumatology Research Foundation Clinician Scholar Educator (CSE) Award. Go to https://sites.duke.edu/rheummadness/ to learn more. RheumMadness is created by David Leverenz, MD, who is the recipient of the CSE award. Dr. Leverenz has also received grant funding from Pfizer for quality improvement work unrelated to RheumMadness.
In this episode, we are joined by two Blue Ribbon Panel members (Dr. Julie Paik and Dr. Angus Worthing) to recap the results of RheumMadness 2023. Plus, we hear from Dr. Nina Couette to review all the RheumMadness-related content on theMednet.org.
Find out more on the RheumMadness website:
https://sites.duke.edu/rheummadness/
Intro/outro music: Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
For this episode, we invited anyone who wanted to join us for a live group discussion about the All Star Season. The result? Our first international guest on the podcast, two more fellow scouting report authors, and a ton of fun. Plus, hear Guy Katz make his picks (so you know who not to pick in the tournament), and hear a rundown of what we think the Blue Ribbon Panel might do.
RheumMadness website: https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the right side of the bracket for RheumMadness 2023 with the scouting report authors. (Part 2 of 2)
RheumMadness website: https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the right side of the bracket for RheumMadness 2023 with the scouting report authors. (Part 1 of 2)
RheumMadness website: https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the left side of the bracket for RheumMadness 2023 with the scouting report authors. (Part 2 of 2)
RheumMadness website: https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the left side of the bracket for RheumMadness 2023 with the scouting report authors. (Part 1 of 2)
RheumMadness website:https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this podcast, we introduce the RheumMadness 2023 tournament and describe how to play.
RheumMadness Website: https://sites.duke.edu/rheummadness/
Intro/outro music:
Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In RheumMadness 2023, EVERYONE can apply to write a scouting report about ANY TEAM that they think is worthy of the title.
Learn how to apply here:
https://sites.duke.edu/rheummadness/
If you'd like to write a scouting report but don't have a group to write one with, please email us at David.Leverenz@Duke.edu
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we reflect on RheumMadness 2022 with members of our leadership team and a Blue Ribbon Panel member (Belinda Birnbaum).
RheumMadness 2022 Post-Survey:
https://duke.qualtrics.com/jfe/form/SV_cMjmiMoQNP0XKGW
Learn more about Vote-ER, a non-partisan organization that helps patients register to vote.
https://vot-er.org/ RheumMadness Website:
https://sites.duke.edu/rheummadness
Podcast Hosts:
- David Leverenz, Assistant Professor at Duke
- Belinda Birnbaum, Blue Ribbon Panelist and rheumatologist at the Bryn Mawr Medical Specialists Association in Bryn Mawr, Pennsylvania.
- Guy Katz, rheumatology fellow at MGH, leadership team member
- Lauren He, internal medicine resident at U Chicago, leadership team member
- Ben Kellog, internal medicine resident at Duke, leadership team member
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we recap the first two rounds of RheumMadness 2022. We are joined by a Blue Ribbon Panelist (Iman Qaiser) who shares what it's been like to be on the panel.
Hosts:
- David Leverenz, Assistant Professor at Duke
- Iman Qaiser, Blue Ribbon Panelist and rheumatology fellow at LSU Health Shreveport
- Guy Katz, rheumatology fellow at MGH
- Michael Macklin, internal medicine resident at UPMC
- Ben Kellog, internal medicine resident at Duke
Subscribe to our newsletter at our website: https://sites.duke.edu/rheummadness
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
Everything you need to know about the RheumMadness tournament.
Find the scouting reports and submit a bracket here:https://www.tourneytopia.com/rheummadness/tournament
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the teams in the People region of the RheumMadness 2022 Tournament. Our DEI discussion topic is disparities in reproductive health care in rheumatology.
Hosts: David Leverenz (Assistant Professor at Duke), Lauren He (resident at the University of Chicago), Cuoghi Edens (Assistant Professor of Medicine and Pediatrics at the University of Chicago), Catherine Sims (Fellow at Duke), and Stacy Bagrova (Fellow at USF).
Subscribe to our newsletter at our website: https://sites.duke.edu/rheummadness
Articles on disparities in reproductive health care in rheumatology:
Kaplowitz ET, Ferguson S, Guerra M, et al. Contribution of Socioeconomic Status to Racial/Ethnic Disparities in Adverse Pregnancy Outcomes Among Women With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2018;70(2):230-235. doi:10.1002/acr.23263
Clowse ME, Grotegut C. Racial and Ethnic Disparities in the Pregnancies of Women With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). 2016;68(10):1567-1572. doi:10.1002/acr.22847
Scouting Reports:
Reproductive Health Guide, written by the Duke University Rheumatology Fellowship Program: Catherine Sims, MD; Sonali Bracken, MD, PhD; Megan Milne, MD; Nathaniel Harris, MD, PhD; Poorva Apte, MD; Lena Eder, MD; Lisa Criscione-Schreiber, MD, Med; Megan Clowse, MD; & David Leverenz, MD
TNFi in Cord Blood, written by Lauren He, MD & Cuoghi Edens, MD from the University of Chicago School of Medicine
Increasing positive ANA, written by Lauren He, MD; Ana B. Arevalo, MD; & Kichul Ko, MD from the University of Chicago School of Medicine
False positive MRI in Axial Spondyloarthritis, written by the University of South Florida Rheumatology Fellowship Program: Anastasiya (Stacy) Bagrova, MD; Shreya Gor, MD; Joanne Valeriano-Marcet, MD; Larry Young, MD; & John Carter, MD
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the teams in the Machines region of the RheumMadness 2022 Tournament. Our DEI discussion topic is disparities in pediatric rheumatology.
Hosts: David Leverenz (Assistant Professor at Duke), Malki Peskin (pediatric rheumatology fellow at Montefiore), Sean Carter (fellow at MUSC), Perry Fuchs (fellow at Cleveland Clinic), Akrithi Garren (Assistant Professor at Georgetown/Medstar), Lisa Criscione-Schreiber (Professor at Duke)
Subscribe to our newsletter at our website: https://sites.duke.edu/rheummadness
Reference article on disparities in pediatric rheumatology: Akinsete AM, Woo JMP, Rubinstein TB. Disparities in Pediatric Rheumatic Diseases. Rheum Dis Clin North Am. 2022;48(1):183-198. doi:10.1016/j.rdc.2021.09.014
Scouting Reports:
Artificial Intelligence: JIA Subtypes, written by the Children’s Hospital at Montefiore Pediatric Rheumatology Fellowship Program: Alisha Akinsete, MD; Malki Peskin, MD; & Jessica Perfetto, MD
Artificial Intelligence: TNFi Response, written by the Cleveland Clinic Foundation Rheumatology Fellowship Program: Saja Almaaitah, MD; Shashank Cheemalavagu, MD; Rupal Shastri, MD; Perry Fuchs, MD; Melany Gonzalez Orta, MD; & James Vondenberg,
DECT in Gout, written by the MedStar Georgetown Washington Hospital Center: Leen Al Saleh, MD; Ajita Acharya, MD; Elena Obreja, MD; & Akrithi U. Garren, MD
PET in LVV, written by the Medical University of South Carolina Rheumatology Fellowship Program: Sean Carter, MD; Jessica English, MD; Brad Collins, DO; Ana Tucker, MD; Jen Schmidt, MD; Whitney Elg-Salsman, DO; & Faye Hant, DO
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the teams in the Animal House region of the 2022 RheumMadness Tournament. Our DEI discussion topic is disparities in osteoarthritis and gout.
Hosts: David Leverenz (Assistant Professor of Medicine at Duke), Ben Kellog (resident at Duke), Melissa Defoe (fellow at UTSW), Nagendra Pokala (fellow at UTSW), Evan Dombrosky (fellow at VCU), Khiem Vu (fellow at Wake Forest), and Jesse Reisner (fellow at Ohio State).
Learn more about RheumMadness by visiting our website: https://sites.duke.edu/rheummadness
References:
Axolotl Limb scouting report by the fellows at Wake Forest Fellowship Program
Dinosaur SpA scouting report by the fellows at Virginia Commonwealth University Fellowship Program
Dalmatian Urate scouting report by the fellows at UT Southwestern Fellowship Program
Dog Osteoarthritis scouting report by the fellows at Ohio State Fellowship Program
Article on disparities in osteoarthritis: Usiskin I, Misra D. Racial Disparities in Elective Total Joint Arthroplasty for Osteoarthritis [published online ahead of print, 2022 Jan 5]. ACR Open Rheumatol. 2022;10.1002/acr2.11399. doi:10.1002/acr2.11399
Article on disparities in gout: Guillén AG, Te Karu L, Singh JA, Dalbeth N. Gender and Ethnic Inequities in Gout Burden and Management. Rheum Dis Clin North Am. 2020;46(4):693-703. doi:10.1016/j.rdc.2020.07.008
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we discuss the teams in the Cells region of the 2022 RheumMadness Tournament. Our DEI discussion topic is increasing diversity in rheumatology clinical trials.
Hosts: David Leverenz (Assistant Professor of Medicine at Duke), Guy Katz (Fellow at MGH), Michael Macklin (Resident at UPMC), Michael Cunningham (Fellow at UNC)
Learn more about RheumMadness by visiting our website: https://sites.duke.edu/rheummadness
References:
Anti-NET antibodies: Zuo Y, Yalavarthi S, Gockman K, et al. Anti-Neutrophil Extracellular Trap Antibodies and Impaired Neutrophil Extracellular Trap Degradation in Antiphospholipid Syndrome. Arthritis Rheumatol. 2020;72(12):2130-2135. doi:10.1002/art.41460
Cytokine networks: Simon Q, Grasseau A, Boudigou M, et al. A Proinflammatory Cytokine Network Profile in Th1/Type 1 Effector B Cells Delineates a Common Group of Patients in Four Systemic Autoimmune Diseases. Arthritis Rheumatol. 2021;73(8):1550-1561. doi:10.1002/art.41697
CAR-T cells (1): Mougiakakos D, Krönke G, Völkl S, et al. CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus. N Engl J Med. 2021;385(6):567-569. doi:10.1056/NEJMc2107725
CAR-T cells (2): Orvain C, Boulch M, Bousso P, Allanore Y, Avouac J. Is There a Place for Chimeric Antigen Receptor-T Cells in the Treatment of Chronic Autoimmune Rheumatic Diseases?. Arthritis Rheumatol. 2021;73(11):1954-1965. doi:10.1002/art.41812
Pim kinases: Maney NJ, Lemos H, Barron-Millar B, et al. Pim Kinases as Therapeutic Targets in Early Rheumatoid Arthritis. Arthritis Rheumatol. 2021;73(10):1820-1830. doi:10.1002/art.41744
SLE clinical trial diversity: Falasinnu T, Chaichian Y, Bass MB, Simard JF. The Representation of Gender and Race/Ethnic Groups in Randomized Clinical Trials of Individuals with Systemic Lupus Erythematosus. Curr Rheumatol Rep. 2018;20(4):20. Published 2018 Mar 17. doi:10.1007/s11926-018-0728-2
RA clinical trial diversity: Strait A, Castillo F, Choden S, et al. Demographic Characteristics of Participants in Rheumatoid Arthritis Randomized Clinical Trials: A Systematic Review. JAMA Netw Open. 2019;2(11):e1914745. Published 2019 Nov 1. doi:10.1001/jamanetworkopen.2019.14745
Critical race theory and SLE trial enrollment: Sneed RS, Mason M, Williams JN, et al. Using Critical Race Theory to Understand Trial Participation Among Black Individuals With Systemic Lupus Erythematosus: A Qualitative Study of Patients and Caregivers. Arthritis Care Res (Hoboken). 2021;73(10):1387-1395. doi:10.1002/acr.24635
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we give a preview of the regions that will be in the RheumMadness 2022 bracket. Our DEI discussion topic is the need to increase diversity in rheumatology training.
Hosts: David Leverenz, Lisa Criscione-Schreiber, Guy Katz, Courtney Bair, Ben Kellog.
Reference: Santhosh & Babik. Trends in Racial and Ethnic Diversity in Internal Medicine Subspecialty Fellowships From 2006 to 2018. JAMA Network Open. 2020;3(2):e1920482.
Learn more about RheumMadness by visiting our website: https://sites.duke.edu/rheummadness
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
A quick update on our plans for RheumMadness 2022. Don't worry - we are still going strong!
To learn more about RheumMadness:
RheumMadness Website: https://sites.duke.edu/rheummadness
Article in the Rheumatologist: https://www.the-rheumatologist.org/article/rheummadness-an-educational-tournament/
If you'd like to join our team or help write a scouting report, please contact us at david.leverenz@duke.edu or on Twitter (message @DavidLeverenz or just tweet using #RheumMadness).
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we are joined by the one and only Dr. Matt Sparks, co-creator of NephMadness, the game that started it all and one of our primary mentors in making RheumMadness. We are also joined by the entire RheumMadness leadership team: Aki Udupa, Didem Saygin, Guy Katz, and Allen Witt.
This episode has everything:
- Reflections on the first year of the tournament
- The true identify of Rheum BOSS
- Hagfish tattoos
- Engagement numbers from RheumMadness2021
- What's next for RheumMadness
Learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
If you're interested in getting involved in planning next year's tournament, contact David.Leverenz@Duke.edu
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, Drs. David Leverenz, Lisa Criscione-Schreiber, Akrithi Udupa, and Guy Katz discuss the results of the first two rounds of RheumMadness and look forward to the IgG Four and the Interleukin Two matchups. We discuss:
-RheumMadness Engagement
-Biggest Upsets / Closest Matchups
-Best Twitter Moments
-Best Bracket Names
-Who we think will win it all
Learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, the fantastic Dr. Lisa Criscione-Schreiber (crucial mentor for the RheumMadness team) reads out the scouting reports for the SLE & ANCA regions of the tournament. Feel free to skip this episode if you've already read the reports. Find the reports and learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Scouting reports included in this episode:
- Belimumab for Lupus Nephritis, written by the Duke University School of Medicine Adult Rheumatology Fellowship Program; Aki Udupa, Ryan Anderson, Isaac Smith, Poorva Apte, Megan Milne, Catherine Sims, Lisa Criscione-Schreiber, and David Leverenz
- Anifrolumab for SLE, written by the Medical University of South Carolina Adult Rheumatology Fellowship Program; Sarah Compton, Sam Minkin, Whitney Elg-Salsman, Ana Tucker, and Jen Schmidt
- PEXIVAS for ANCA vasculitis, written by the Medical College of Wisconsin Adult Rheumatology Fellowship Program
- Avacpoan for ANCA vasculitis, written by the Northwestern University Adult Rheumatology Fellowship Program; Kaitlin Lima, Michael Lopker, Yoon Qiu, Julia Sun
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, the fantastic Dr. Lisa Criscione-Schreiber (crucial mentor for the RheumMadness team) reads out the scouting reports for the Miscellaneous and Small but Mighty regions of the tournament. Feel free to skip this episode if you've already read the reports. Find the reports and learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Scouting reports included in this episode:
- IgG4-RD Classification Criteria, written by the Massachusetts General Hospital Adult Rheumatology Fellowship Program; Guy Katz, MD; Ian Cooley, MD; Duncan F Moore, MD; Naomi Patel, MD
- Relapsing Polychondritis Subtypes, written by the Wake Forest School of Medicine Adult Rheumatology Fellowship Program; Page Bomar, Rami Diab, John Herion, Yael Klionsky
- Anti-CD38 in Refractory Lupus, written by the University of North Carolina Adult Rheumatology Fellowship Program; Leah Bettner, Shruti Chandramouli, Amanda Lusa, Christopher Overton, and Enid Sun
- VEXAS, written by the RheumMadness Leadership Team
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we read the scouting reports on the teams in the steroids & MSK regions of the tournament. Feel free to skip this episode if you've already read the reports. Find the reports and learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Scouting reports included in this episode:
- SEMIRA, written by the Allegheny Health Network Adult Rheumatology Fellowship Program; Osman Bhatty MD, Padmini Parameswaran MD, Christon Grant MD, Mohamed Tageldin, MD, Michael Lucke, MD
- Harms of Short Term Steroids, written by the University of Kentucky Adult Rheumatology Fellowship Program; Amna Batool, Susan Mansourian, Elise McVeigh, Saurav Suman, Kristine Lohr
- UK Frost for Frozen Shoulder, written by C. Allen Witt (RheumMadness Leadership Team)
- PT vs. GC Injection for Knee OA, written by the Oschner Medical Center Adult Rheumatology Fellowship Program; Dr. Ronak Patel, Dr. Chad Hille, and Dr. Chandana Keshavamurthy
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode, we read the scouting reports on the RA and gout teams in the tournament. Feel free to skip this episode if you've already read the reports. Find the reports and learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Scouting reports included in this episode:
PRIME Cells in RA, written by the University of Colorado Adult Rheumatology Fellowship Program
* Synovial B Cells & Therapy Response in RA (R4RA), written by the Vanderbilt University School of Medicine Adult Rheumatology Fellowship Program
* FAST Study, written by the University of Chicago Adult Rheumatology Fellowship Program; Didem Saygin, Emily Peninger, Laarni Quimson, Marco Lopez-Velazquez, Kichul Ko
* ACR Gout Guidelines*, written by the Loma Linda University Adult Rheumatology Fellowship Program; Donna Jose, MD and Marven Cabling, MD
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
New to RheumMadness? Want to submit a bracket but don't know where to start? Listen to this episode for a brief explainer on how RheumMadness works. Learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode David Leverenz, Aki Udupa, Didem Saygin, and Guy Katz discuss the second half of the RheumMadness bracket. The first half was covered in the previous episode (Bracketology Part 1). You can learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
References for topics discussed in this episodeSEMIRA Study in RA: Burmester et al. Lancet.2020;396(10246):267-76 (pubmed link)
Harms of Short Term Steroids: Yao et al. Ann Intern Med.2020;173(5):325-30 (pubmed link)
UK FROST Trial for Frozen Shoulder: Rangan et al. Lancet.2020;396(10256):977-89 (pubmed link)
PT vs. GC Injection for Knee Osteoarthritis: Deyle et al. NEJM.2020;382(15):1420-29 (pubmed link)
PRIME Cells in RA: Orange et al. NEJM.2020;383(3):218-28 (pubmed link)
Synovial B Cells and Therapy Response in RA: Humby et al. Lancet.2021;397(10271):305-17 (pubmed link)
FAST Study in Gout: Mackenzie et al. Lancet.2020;396(10264):1745-57 (pubmed link)
ACR 2020 Gout Guidelines: Fitzgerald et al. AC&R.202072(6):744-60 (pubmed link)
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode David Leverenz, Aki Udupa, Didem Saygin, and Guy Katz introduce the first half of the RheumMadness bracket. The second half will be covered in the next episode (Bracketology Part 2). You can learn more about RheumMadness here: https://sites.duke.edu/rheummadness/
References for topics discussed in this episodeBelimumab for Lupus Nephritis: Furie et al. NEJM.2020;383(12):1117-28 (pubmed link)
Anifrolumab for SLE: TULIP-1 and TULIP-2 trials (click for links)
PEXIVAS in ANCA Vasculitis: Walsh et al. NEJM.2020;382(7):622-31 (pubmed link)
Avacopan in ANCA Vasculitis: Jayne et al. NEJM.2021;384:599-609 (NEJM link)
IgG4-RD Classification Criteria: Wallace et al. A&R.202072(1):7-19 (pubmed link)
Relapsing Polychondritis (RP) Subtypes: Ferrada et al. A&R.202072(8):1396-1402 (pubmed link)
Anti-CD38 in Refractory SLE: Ostendorf et al. NEJM.2020;383(12):1149-55 (pubmed link)
VEXAS: Beck et al, NEJM.2020;383:2628-38 (pubmed link)
Intro and Outro music:Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode we welcome Dr. Didem Saygin, a rheumatology fellow from the University of Chicago, to the podcast. We are also joined by Dr. Guy Katz, a rheumatology fellow from MGH. We discuss three more topics that would be excellent teams in the upcoming RheumMadness tournament: the newly discovered VEXAS autoinflammatory syndrome, the FAST trial on cardiovascular safety of urate-lowering therapies, and the PEXIVAS trial in ANCA vasculitis.
New RheumMadness website!
https://sites.duke.edu/rheummadness/
References:
VEXAS: https://www.nejm.org/doi/full/10.1056/NEJMoa2026834
FAST: https://www.thelancet.com/article/S0140-6736(20)32234-0/fulltext
PEXIVAS: https://www.nejm.org/doi/full/10.1056/NEJMoa1803537
RheumMadness Music Attribution: Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
In this episode we welcome guests Dr. Akrithi Udupa and Dr. Allen Witt from Duke, and Dr. Guy Katz from MGH to discuss four topics from the 2020 ACR Convergence conference that could be teams in the upcoming RheumMadness tournament. The topics we discuss are:
1. Draft 2020 RA Guidelines
2. Belimumab for Lupus Nephritis
3. Pregnancy with ILD in Rheumatic Disease
4. IL-16 as a Biomarker of Lupus Nephritis
RheumMadness Music Attribution: Cheery Monday by Kevin MacLeod
Link: https://incompetech.filmmusic.io/song/3495-cheery-monday
License: http://creativecommons.org/licenses/by/4.0/
Dr. Aki Udupa and Dr. Allen Witt are back to discuss:
-Rheuminders from the previous episode on relapsing polychondritis subtypes
-Primer on RA pathophysiology
-A new study (see below) using longitudinal genomics to provide new insights into the pathogenesis of RA flares and describing a new type of cell: PRIME cells.
Reference: Orange DE, Yao V, Sawicka K, Fak J, Frank MO, Parveen S, Blachere NE, Hale C, Zhang F, Raychaudhuri S, Troyanskaya OG, Darnell RB. RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares. N Engl J Med. 2020 Jul 16;383(3):218-228. doi: 10.1056/NEJMoa2004114. PMID: 32668112; PMCID: PMC7546156.
Intro and Outro music: Cheery Monday by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3495-cheery-mondayLicense: http://creativecommons.org/licenses/by/4.0/
This episode includes:
-Rheuminders from the previous episode on IgG4-RD classification criteria
-Primer on relapsing polychondritis
-Discussion of a new paper (see below) describing 3 clinical subtypes of relapsing polychondritis
Reference: Ferrada M, Rimland CA, Quinn K, Sikora K, Kim J, Allen C, Sirajuddin A, Goodspeed W, Chen M, Grayson PC. Defining Clinical Subgroups in Relapsing Polychondritis: A Prospective Observational Cohort Study. Arthritis Rheumatol. 2020 Apr 6. doi: 10.1002/art.41270. Epub ahead of print. PMID: 32249511.
Intro and Outro music: Cheery Monday by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3495-cheery-mondayLicense: http://creativecommons.org/licenses/by/4.0/
Dr. Akrithi Udupa (fellow at Duke) and Dr. Allen Witt (resident at Duke) join the podcast to discuss IgG4-RD and the new classification criteria published by Wallace et al in Arthritis & Rheumatology in January 2020.
Reference: Wallace et al. The 2019 American College of Rheumatology / European League Against Rheumatism Classification Criteria for IgG4-Related Disease. Arthritis & Rheumatology. 2020;72(1):7-19.
Intro and Outro music: Cheery Monday by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3495-cheery-mondayLicense: http://creativecommons.org/licenses/by/4.0/
Introduction to the RheumMadness Podcast!
Intro and Outro music: Cheery Monday by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/3495-cheery-mondayLicense: http://creativecommons.org/licenses/by/4.0/