Here is a brief description of Robert Koch and his contributions to Medical Microbiology. It emphasizes the Koch's postulates that basically links the pathogen to the disease caused by that pathogen.
Anthrax bacilli - isolated and cultured - from diseased mouse -
inoculated into a healthy mouse
re-isolated and
identified as Anthrax bacilli.
Valid, biological and scientific questions are risen as part of scientific enquiry. The answered can be found through the Koch's postulates.
This podcast describes the shape of the Anthrax bacilli and how Koch obtained isolated colonies.
This podcast describes how Koch proved that the specific pathogen is the one causing the specific disease.