Welcome to the Informonster Podcast, a podcast about the Healthcare IT industry hosted by Charlie Harp, CEO of Clinical Architecture. This podcast fosters an educational and professional discussion about healthcare information technology, including events in the industry, interviews with thought leaders, and much more! Have a topic you want discussed on the podcast? Email us at informonster@clinicalarchitecture.com.
Artificial intelligence is everywhere in healthcare, but how much of it is actually making a meaningful impact?
In Episode 53 of The Informonster Podcast, Charlie Harp sits down with Dr. Steve Labkoff and Dr. Leon Rozenblit, co-hosts of the Practical AI in Healthcare podcast, to discuss their backgrounds in informatics, the inspiration behind their podcast, and what they've learned from speaking with healthcare leaders at the forefront of AI adoption.
The conversation explores the difference between hype and real-world results, why AI literacy is becoming increasingly important, how healthcare organizations can identify practical use cases, and the critical role data quality plays in building trustworthy AI solutions.
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In this episode, Charlie Harp discusses why healthcare’s long-standing definition of “good enough” data no longer works in a world increasingly driven by interoperability, analytics, and AI. Drawing from a recent presentation at the AMIA Amplify Conference 2026, Charlie breaks down the growing gap between the way healthcare data was originally designed to function and the way organizations are now trying to use it.
From interoperability and population health to clinical decision support and generative AI, Charlie explores how healthcare organizations are asking data to do far more than it was ever designed to do. He also breaks down the six dimensions of data quality and why issues like integrity, relevance, liquidity, usablity, granularity, and trust have become critical to the future of intelligent healthcare systems.
The conversation also dives into the risks of “uncalibrated uncertainty,” the hidden dangers of low-quality data powering AI systems, and why healthcare leaders need to rethink how they evaluate, govern, and invest in data quality before the consequences become much harder to ignore.
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In this episode, Charlie sits down with Clinical Architecture's VP of Marketing, Jaime Lira, to unpack the whirlwind of the spring healthcare conference season.
From ViVE and HIMSS to the CMS Quality Conference and the ASTP Annual Meeting, they cover what made this year's circuit stand out. Including why booth conversations felt deeper than ever, how different conferences serve completely different purposes, and what it really looks like to be a vendor navigating it all.
They also dive into the growing importance of data quality across the industry, the value of community groups like Swaay and Bluebird Leaders, and some honest advice for anyone trying to figure out where to spend their conference budget.
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In Episode 50 of the Informonster Podcast, Charlie Harp sits down with Rachel Dunscombe, CEO of HL7 International, to talk about her journey through healthcare, digital transformation, and standards development.
Rachel shares the experiences that shaped her perspective on interoperability from leading digital initiatives within the NHS to now working at the center of standards development as CEO of HL7 International. Charlie and Rachel discuss the role HL7 plays in supporting modern healthcare infrastructure, enabling new models of care, and helping clinical data move more effectively across systems.
They also explore the growing intersection of AI and healthcare data, why strong standards and terminology still matter, and what the future may hold for the global healthcare standards community.
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In Episode 49 of the Informonster Podcast, Charlie Harp sits down with Gene Vestel, host of Out of the FHIR Podcast and founder of FHIR IQ.
Gene shares his journey from pharmacy analytics to leading FHIR initiatives and advising organizations on digital quality measurement. He and Charlie discuss how FHIR has evolved, where it delivers value, and where organizations still struggle to make exchanged data truly computable.
They also explore AI and data quality and why governance and provenance matter more than ever. Gene offers his perspective on the future of US Core and what it will take to move from simply exchanging data to actually making it usable.
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In Episode 48 of the Informonster Podcast, Charlie Harp is joined by Clinical Architecture’s UK team members Chris Gray and Alex Wren to explore how pharmacogenomics is moving from research into real-world clinical practice.
They dive into the Progress Project, a groundbreaking NHS initiative integrating genetic insights directly into clinical workflows to support safer, more personalized medication prescribing. From building the technical foundation to delivering real-time decision support at the point of care, Chris and Alex share what it takes to turn precision medicine into everyday healthcare.
Tune in to learn how the UK is advancing genomics, improving outcomes, and shaping the future of personalized care.
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Healthcare access isn’t just about availability, it’s about data. In this episode of The Informonster Podcast, Charlie Harp sits down with Sarah Matt, MD, MBA, Health Technology Strategist, and author of The Borderless Healthcare Revolution, to explore how gaps in healthcare data continue to create barriers for patients, providers, and caregivers alike.
Dr. Matt shares insights from her career spanning clinical practice, health tech startups, and large-scale healthcare transformation, unpacking how inconsistent, incomplete, and fragmented data undermines care delivery, limits the effectiveness of AI, and contributes to provider burnout. The conversation covers interoperability challenges, why “the average patient doesn’t exist,” and what it will really take to improve access without “burning down” the healthcare system.
If you’re interested in healthcare access, data quality, AI in medicine, and the future of patient-centered care, this episode offers a thoughtful and grounded perspective from someone who’s lived it from every angle.
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In Episode 46 of the Informonster Podcast, Charlie Harp sits down with John D’Amore a leading voice in healthcare informatics, data standards, and interoperability.
From his early days in decision support to building and selling a data normalization company, John shares the experiences that shaped his career and the lessons he’s learned along the way. Together, Charlie and John dig into the evolution of interoperability, why data quality matters more than ever, and how standards like IPS and CCDA continue to influence care delivery across the globe.
They also explore the intersection of AI and data quality, the realities of modern EHRs, and why the next generation of informatics professionals will shape the future of healthcare. John also weighs in on the growing momentum behind the Patient Information Quality Improvement (PIQI) Framework and why establishing a shared, consistent approach to measuring data quality is critical for the industry.
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In Episode 45 of The Informonster Podcast, host Charlie Harp sits down with Ryan Howells, Principal at Leavitt Partners, to explore how collaboration, policy, and open standards are driving meaningful innovation in healthcare.
From the origins of the “Kill the Clipboard” initiative to the push for better data quality, Ryan shares how he and his team at Leavitt Partners are helping align government and industry leaders to improve the quality and usability of health data exchange. The conversation dives into digital quality measures, the evolution of HIPAA, and why an abundance mindset could be the key to transforming healthcare data exchange.
If you’re passionate about healthcare policy, interoperability, or the future of data-driven care, this episode is a must-listen.
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In this episode of the Informonster Podcast, Charlie Harp is joined by Sarah DeSilvey, DNP, FNP-C, Co-founder and Director of Terminology for the Gravity Project, to discuss the evolution of data standards supporting social determinants of health (SDOH). Together, they explore how Gravity’s collaborative work within HL7 is helping define and standardize social care data to improve interoperability and care coordination.
Sarah shares insights into the project’s origins, its impact on initiatives like USCDI and quality measurement, and the critical role of consensus-based data development. The conversation highlights how advancing SDOH data standards not only strengthens health data quality but also enables more equitable, person-centered care.
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In this episode of the Informonster Podcast, Charlie Harp takes on a new kind of guest, ChatGPT, to explore the evolving role of artificial intelligence in healthcare.
Together, they discuss how generative AI is shaping clinical workflows, where it adds value, and where human oversight remains essential.
The conversation covers topics from bias and data quality to the ethical guardrails needed to keep AI trustworthy.
Charlie also reflects on how tools like ChatGPT can accelerate progress while highlighting why high-quality data and human expertise will always be at the heart of meaningful innovation.
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In this episode of the Informonster Podcast, Charlie Harp sits down with healthcare IT rockstar Susan Clark for a candid conversation on the evolving world of healthcare policy. From the incentives that drive real change, to the challenges of interoperability, data quality, and patient identity, Susan shares her insights on what it takes to align policy with purpose.
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In this episode of the Informonster Podcast, Charlie Harp shares updates on the PIQI Framework and his experience at the HL7 Connectathon. He highlights progress across newly formed PIQI Alliance work groups, from claims and explanation of benefits to USCDI and quality measures like eCQMs and HEDIS. He also talks about new SAM developments, including detection and noise, and how community feedback is shaping PIQI’s evolution to strengthen healthcare data quality.
Charlie also reflects on his first Connectathon, where PIQI sparked engaging discussions and valuable feedback from across the HL7 community. The experience underscored the collaborative spirit and shared commitment to advancing data quality in healthcare.
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Joerg Schwarz, Senior Director, Global Industry Strategy & Solutions, Healthcare Data & Interoperability of Infor joins Charlie Harp to explore the future of healthcare data. They unpack how AI is raising the bar for interoperability, why data quality can’t be an afterthought, and how the PIQI Alliance is bringing the industry together to drive meaningful change. From FHIR adoption to scalable innovation, Joerg shares real-world insight into where healthcare data needs to go next.
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In this episode of the Informonster Podcast, Clinical Architecture CEO Charlie Harp hands over the mic to our VP of Marketing, Jaime Lira, for a conversation about the evolution of the PIQI Framework. From its early beginnings as a taxonomy to its growing momentum across the industry, Charlie shares how PIQI has progressed, what’s coming next for the PIQI Alliance, and why standardizing patient data quality is more important than ever.
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In this episode of The Informonster Podcast, Charlie Harp sits down with Michael Klotz, Founder and CEO of Velox, to explore how Velox is helping payers move toward smarter, more streamlined access to clinical data. They discuss how the Velox platform helps payers benchmark and improve data quality, and how shared standards and smart analytics are laying the groundwork for a more connected, responsive healthcare system. The episode also covers our partnership, which merges Velox’s data platform with tools like PIQXL Gateway to score the quality and remediate issues. Plus, hear the story behind Velox’s signature “green donut” dashboard—an eye-catching KPI that’s becoming a symbol for clean, real-time, FHIR-based clinical data.
Learn more about our partnership here.
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Join Charlie Harp and Carol Macumber, EVP of Client Services at Clinical Architecture and Chair-Elect of the HL7 Board of Directors, as they unpack Carol's informatics work and her participation in HL7 through the years. From Carol's early days in informatics to leading initiatives like Gender Harmony, this episode takes a deep dive into the organization’s efforts to standardize healthcare data exchange.
They break down the evolution of FHIR, the hurdles of achieving true semantic interoperability, and how AI is shaking up healthcare standards.
Read more about her chair-elect announcement here.
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In this episode of The Informonster Podcast, Charlie Harp talks with John A. Short, MBA, MS-IS, FEMA PDS, CPHIMS, Senior Executive Service (SES), Director, Federal & Commercial Interoperability of Federal Electronic Health Record Modernization (FEHRM) Office and John Rancourt, Deputy Director of ASTP’s Office of Standards, Certification, and Analysis. They discuss how the government, specifically the DoD and VA, are addressing the challenges and opportunities in healthcare interoperability. They cover key topics such as USCDI, TEFCA, and the role of data standards in improving care and reducing costs. The discussion also highlights how data quality and trust play a crucial role in advancing AI and creating a more connected healthcare system.
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Charlie Harp is joined by Dr. Victor Lee, VP of Clinical Informatics at Clinical Architecture, to take a deep dive into how a methodical approach to value set creation and maintenance builds a solid foundation for downstream data analysis and improved healthcare outcomes.
Dr. Lee introduces the 6 Cs Framework he developed to evaluate value set quality through dimensions like clarity, completeness, congruency, consistency, correctness, and currency.
They discuss common pitfalls, the impact of high-quality value sets on clinical decision support, and why value set maintenance is essential over time.
Download the full report for a fresh perspective on creating and sustaining value sets that make a difference in real-world healthcare outcomes.
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In this episode of The Informonster Podcast, Charlie Harp and Clinical Architecture’s Vice President of Marketing, Jaime Lira, dive into the insights from the 2024 Data Quality Report.
As they explore key trends from this year’s survey, the discussion highlights the increasing recognition of data quality's critical role in healthcare, impacting everything from population health to AI initiatives.
Download the full report below and sign up to be a part of the 2025 survey to help shape the future of healthcare data quality.
Download the 2024 Data Quality Report
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Are you tired of dealing with unreliable data that hinders your decision-making process? Join Charlie Harp, the host of the Informonster Podcast, as he explores issues impacting data quality and explains how Simple Assessment Modules (SAMs) function within the PIQI framework.
In the final episode of our Data Quality in Healthcare series, Charlie guides you through the intricacies of SAMs which are specialized tests designed to evaluate the quality of your data entities for specific use cases. Discover how these plug-and-play modules can seamlessly integrate into evaluation profiles, allowing you to assess your data against a battery of relevant criteria.
Charlie also explains the concept of evaluation profiles, which establishes a comprehensive framework for measuring and assessing your information entities. You'll learn how these profiles produce quality scores and provide detailed statistics, empowering you to make informed decisions based on reliable data.
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In the third installment of the Data Quality in Healthcare series, Charlie Harp explores the taxonomy of the PIQI Framework. He breaks down the primary categories of 1.) Delivery and 2.) Intrinsic Issues, and shows how the subcategories a.) availability b.) accuracy c.) conformity and d.) plausibility are used to analyze and address data quality challenges.
Come back for part four where Charlie talks about Simple Assessment Modules (SAMs) and the elegant simplicity of recursive failure.
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Tune in as Charlie Harp unveils the rationale behind the Patient Information Quality Improvement’s (PIQI) streamlined data model, and explains how it turns complex patient information into an organized format for analysis. The next episode will cover the taxonomy that was used in the PIQI framework to identify the root causes of data issues and provide recommendations for improvement.
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When looking for a practical way to assess the quality of patient information from external sources, Charlie Harp found that existing frameworks were either too general or too specific to certain databases or schemas. So, he created the Patient Information Quality Improvement (PIQI) framework. In the second episode of the "Data Quality in Healthcare" series, Charlie gives a high-level overview of the PIQI framework and shares some use cases for this structure. Tune in as he shares the ultimate goal for the framework which is to enhance the quality of patient information to provide better outcomes and care across the healthcare industry.
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It’s time to take a closer look at healthcare data quality. This episode is the beginning of a series related to the challenges that all healthcare professionals face in gathering, organizing, and using patient data. Join the conversation as Charlie Harp shares how we got to this place as an industry and a solution for measuring the quality of patient information. Listen now to learn about the Patient Information Quality Improvement (PIQI) framework and how it can be used to help healthcare professionals make better informed decisions.
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In this episode of The Informonster podcast, Charlie Harp talks with Janice Kelly, President of AORN Syntegrity, Inc., (Association of periOperative Registered Nurses) with over 25 years of informatics experience. Janice shares how AORN is working to enhance workflows with surgical schedules and perioperative nursing. She also gives insights into how AORN collaborates with healthcare institutions to stay ahead of the curve when it comes to new procedures, CPT codes, and preference cards.
Charlie and Janice explore the unexpected ways data quality impacts healthcare and how AORN's contributions are helping healthcare professionals maintain the gold standard in procedure lists and standard terminologies.
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In this episode of the Informonster Podcast, Charlie Harp sits down with Patina Zarcone, Director, and Millie Malai, Technical Project Manager of Datapult, an APHL company. They discuss how Datapult and Clinical Architecture came together to create a system that would get lab data to public health faster, especially during the pandemic. They discuss the impact of this system on the timeliness of data for emerging infectious diseases, and how converting data from CSV to HL7 v2.5.1 was a game changer to ensure that public health received the highest quality data.
About Patina Zarcone
Patina (Zarcone) Gagne serves as the Association of Public Health Laboratories’ (APHL) Director of Datapult, a new APHL company, and has been with APHL approaching 21 years. When joining APHL in 2003, Patina was the only informatics staff member focused primarily on helping governmental public health laboratories acquire laboratory information management systems. Today, she is running Datapult, a company that made a major impact on the pandemic by reporting COVID laboratory results electronically to public health. Prior to her tenure at APHL, Patina worked first in biotechnology as a bench scientist in gene therapy for Biogen Inc., in Cambridge MA then went on to work for the Massachusetts Department of Public Health, State Laboratory Institute helping run operations for the mosquito borne disease surveillance program.
Patina has an undergraduate degree (BA) in Biology from Boston University and a Master’s Degree in Public Health (MPH), specializing in Health Service Administration also from Boston University.
Patina lives in Newbury, MA right next to the Atlantic ocean with her husband, Joel Gagne Esq. and 4 children.
About Millie Malai
Millie is the Technical Project Manager for Datapult and oversees technical development and implementation across Datapult’s service, including Expanded ELR. She has been in the field of public health informatics for over a decade, with experience in syndromic surveillance systems, laboratory information systems, immunization registries, electronic laboratory reporting, and health data interoperability. She holds a Master of Public Health with a concentration in applied public health informatics from Emory University, Rollins School of Public Health.
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On this episode of the Informonster Podcast, Charlie discusses the importance of data quality and how it impacts the results of any analysis or decision-making process. He also shares insights from our inaugural survey which indicates that the industry recognizes the importance of data quality but acknowledges that it is a challenging effort.
Download the Data Quality Survey Report here: https://clinicalarchitecture.com/data-quality-survey/
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In this episode Charlie Harp talks with Lori Moore, Public Health Analyst and Stuart Myerburg, Informatics Team Lead with the CDC's National Center for Immunization and Respiratory Diseases (NCIRD) group, as they discuss what it’s like managing data around vaccines, the challenges they faced and opportunities they discovered while going through the COVID-19 crisis.
On this episode of the Informonster Podcast, Charlie provides a high-level primer on Observational Medical Outcomes Partnership (OMOP). He also discusses terminologies and adding data into an OMOP data repository. To learn more about OMOP please visit ohdsi.org.
On this episode of the Informonster podcast, Charlie Harp is joined by Janet Campbell, Software Developer and Vice President of Patient Engagement at Epic, Chris Grasso, Chief Information Officer at Fenway Health and Carol Macumber, Executive Vice President at Clinical Architecture to discuss the HL7 Gender Harmony Project.
On this Episode of the Informonster Podcast, Charlie Harp talks with Drew Ivan, Chief Strategy Officer at Lyniate, about cross-organization interoperability, patient interoperability from consumer devices, why we interoperate, and how all of it affects our relationship with trust.
On this episode of the Informonster Podcast, Charlie is on the road talking about the relationship between clinical lab data and interoperability. He talks about LOINC, as well as the use of lab data in AI and machine learning, and some of the challenges faced in these applications.
On this episode of the Informonster Podcast, Charlie Harp talks about the purpose of the CMS Hospital Price Transparency Initiative, how price transparency would be implemented in our current system, as well as the difficulties we would have to face in order to achieve it.
This two-part episode of the Informonster Podcast features Steve Bratt and Carmela Couderc from MITRE, along with Charlie Harp, Carol Macumber, and Shaun Shakib. The group discusses why a community-based approach, while foreign, is so beneficial to the industry, busting the myth that organizations can contribute to the standard without exposing their own secrets. They also talk about the future of mCode.
This two-part episode of the Informonster Podcast features Steve Bratt and Carmela Couderc from MITRE, along with Charlie Harp, Carol Macumber (EVP – Client Services at Clinical Architecture), and Shaun Shakib (Chief Informatics Officer at Clinical Architecture). Steve, Health Technology Principle at MITRE, is the Program manager of the Common Oncology Data Elements Extensions (CodeX) HL7 FHIR Accelerator. Carmela, is a Clinical Informaticist at MITRE, working across CodeX use cases. Steve and Carmela take a deep dive into the history and accomplishments of the growing CodeX community that is working together to leverage standardized collection and exchange of oncology data via the minimal Common Oncology Data Elements (mCODE) HL7 FHIR Standard for Trial Use.
Does Healthcare leverage public health data effectively? On this episode of the Informonster Podcast, Dr. Don Rucker, former National Coordinator for the ONC, joins Charlie Harp to discuss how Health Information Exchanges are in a unique position to re-imagine and pioneer broad-based public health approaches to data.
On this episode of the Informonster Podcast, Charlie Harp discusses the importance of attaching accurate details to terms in a system in order to provide a window into the thought process of the scribe. He discusses treating term definitions as personal notes and how doing so keeps the system from having the same term defined in 73 different ways. He also explains how having this infrastructure in place could mitigate the effects of Clinical Emergencies like COVID-19.
On this episode of the Informonster Podcast, Charlie Harp meets with CommonWellHealth Alliance Executive Director, Paul Wilder, and Director of Product, Liz Buckle, to discuss the organization’s mission to provide universal access to data at the point of care for the right clinician and the right patient. While the goal is simple, getting there is incredibly complex. Charlie explains why Clinical Architecture decided to join this alliance, and both Paul and Liz talk about how they’ve been able to connect and share data through their growing nationwide network with the help of their members and initiatives like the CommonWell Connector™ program. The group also shared insights on how federal regulations have affected the push to universal interoperability and the importance of ensuring data quality along the way.
Charlie Harp is joined by Logica’s Chair of the Board, Stan Huff, Chair of the Nursing LOINC Subcommittee, Susan Matney, along with Clinical Architecture’s very own Chief Informatics Officer Shaun Shakib and EVP of Client Services Carol Macumber to discuss the history and impact of Logica on the Healthcare IT Industry. In this second part of the Informonster Podcast’s first two-part series, they discuss the importance of information modeling’s interaction with terminology, how a standard by itself can only be effective if we all agree to follow it, treating decision support like a medical device, how Logica is changing, and howdecision support can ease provider burden in the trenches with open and reliable data.
Charlie Harp is joined by Logica’s Chair of the Board, Stan Huff, Chair of the Nursing LOINC Subcommittee, Susan Matney, along with Clinical Architecture’s very own Chief Informatics Officer Shaun Shakib and EVP of Client Services Carol Macumber to discuss the history and impact of Logica on the Healthcare IT Industry. In this first part of The Informonster Podcast’s first two-part series, they discuss Logica’s growth and accomplishments, and how, even with COVID-19, Logica gets the medical community to leave their “silos” and buy in while remaining nimble and responsive.
In this episode of the Informonster Podcast, Charlie Harp talks about the notions of standardization and normalization, what they mean in the context of healthcare terminologies, and their relative pros and cons.
On this episode of the Informonster Podcast, Charlie Harp discusses FHIR, from its design, history and implementations to its unique quirks and possible future uses, with Clinical Architecture’s own FHIR Services Product Manager, Carol Graham, and EVP of Client Services, Carol Macumber.
In this episode of the Informonster Podcast, Charlie Harp talks about the origins and importance of allergies and tolerances in Healthcare IT, as well as what makes them unique from other terms within the system. He then discusses how different systems handle allergies and intolerance as well as the issues that come up with them and how he thinks they could be solved.
On this episode of the Informonster Podcast, Charlie Harp is joined by Randy Woodward, Carol Macumber and Victor Lee, MD, to talk about the COVID 19 Interoperability Alliance, an initiative designed to provide value sets and resources to identify, understand and monitor COVID-19 information patterns. They discuss why the Alliance was formed, the problems the industry is currently facing and how the Alliance can help combat the pandemic.
Episode 8: What is the USCDI?In this episode of the Informonster Podcast, Charlie Harp talks about the United States Core Data for Interoperability (USCDI), how the 21st Century Cures Act brought it into being, an overview of the data classes and elements, and some considerations that could impact its success.
On this episode of the Informonster Podcast, Charlie Harp discusses the history of ICD-10. He talks about how it was created and evolved with the healthcare industry, and what he thinks the next iteration could do to improve for the industry going forward.
On this episode of the Informonster Podcast, Charlie Harp talks about how healthcare evolves from the edges, three core types of patient data, and the three takeaways from the COVID-19 Pandemic that can help us be more prepared for the future.
In this episode of the Informonster Podcast, Charlie Harp tackles the concept of terminologies in healthcare, the many places you find them and their relevance to the enterprise, our industry, and you.
In this episode of the Informonster Podcast, Charlie sits down with Clinical Architecture thought leaders Shaun Shakib, MPH PhD, Andrew Frangleton, and Victor Lee, MD, to discuss SNOMED. They will talk about what SNOMED is, how it used by healthcare applications, the benefits of using SNOMED, potential obstacles and how to avoid them
Charlie welcomes Randy Woodward, RN and Senior Clinical Architect as a guest on the podcast to discuss topics relating to applied automation in healthcare IT, including RPA vs AI, patterns of success and omens of failure, and the value automation brings to the industry. Charlie and Randy also discuss the nature of healthcare, and how that relates to the best perspective one should have on automation. Those who are interested should stay tuned at the end of the episode to hear Randy discuss how Clinical Architecture’s products work relevant to automation.
For this episode, Charlie Harp, CEO of Clinical Architecture, gives a primer on interoperability, as well as why it matters. He also discusses ideas such as the responsibility of the receiver and the dangers of Conceptual Echo.
For this first episode, Charlie Harp, CEO of Clinical Architecture, talks about the purpose of the Informonster Podcast. This includes a short journey through the history of Clinical Architecture, as well as a perspective on the objectives of healthcare IT, the barriers to achieving them and the mindset needed to overcome them.