Med School Radio - Simon R. Downes: Recent Episodes

Simon R. Downes, MD, PhD student

Subjects related to medical school class content, and the United States Medical Licensing Examination (USMLE). (Not affiliated with the NBME or USMLE). Simon R. Downes, PhD, MD student

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General review

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Episode 393: FA REVIEW PP 724-725

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Episode 392: FA REVIEW PP 722-723

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Episode 391: FA REVIEW PP 720-721

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Episode 390: FA REVIEW PP 718-719

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Episode 389: FA REVIEW PP 716-717

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FA REVIEW PP 714-715

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FA REVIEW PP 712-713

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FA REVIEW PP 710-711

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USMLE EOS

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FA CS CASES

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FA CS CASES

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FA CS CASES

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FA CS QUs FOR PT

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FA CS MINI CASES

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FA CS MINI CASES

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FA CS MINI CASES

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FA CS MINI CASES

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FA MINI CASES

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FA MINI CASES

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FA MINI CASES

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USMLE prep

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USMLE Step 1

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USMLE concepts

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USMLE

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25 EOs for the USMLE

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Review

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Yep. More EOs

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USMLE educational objectives

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EOs 3

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I’m just reading educational objectives

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Malabsorption syndromes

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Great way to prep for USMLE

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Neuroscience

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Microbiology and infectious diseases

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Nutrition

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Biochemistry review foe the USMLE

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Respiratory system for the USMLE

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Respiratory system for USMLE

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Reverse MCQs for Immunopathology - USMLE Step 1

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USMLE Step 1 review #28

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Oceania University of Medicine interviewed me regarding my final year and experiences studying at OUM - the first medical school to incorporate an online component into their curriculum.

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日本語で自己紹介をします。よろしくお願いします。アメリカ医学生の臨床研修をやっています。Interview on Japanese radio in 2008 and today - PhD to MD.

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I am using DIT and Dr. Fischer's Integrated cases (MedQuest) to improve my USMLE prep

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USMLE STEP 1 prep

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MSR NEWS

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Reading Zanki to prepare for the USMLE Step 1

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Step one review

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USMLE review

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Rapid COVID test while reading REPRODUCTIVE ANKI (ZANKI) for the USMLE

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USMLE review #26

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FA 2020 - p122 Therapeutic antibodies

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FA 2020 - p120-121 Immunosuppressants and recombinant cytokines and clinical uses

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FA 2020 - p119 transplant rejection

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FA 2020 - p116-118 immunodeficiencies

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FA 2020 - p114-115 blood transfusion reactions and autoantibodies

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FA 2020 - p112-113 hypersensitivity types

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FA 2020 - p111 Vaccination

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FA 2020 - p110 cell surface proteins, passive versus active immunity

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FA 2020 - p109 The respiratory burst and interferons

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FA 2020 - p108 Important cytokines

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FA 2020 - p107 Complement disorders

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FA 2020 - p106 Complement

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FA 2020 - p105 Immunoglobulin isotypes, antigen type and memory

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FA 2020 - p104 Antibody structure and function

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FA 2020 - p103 T and B cell activation

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FA 2020 - p102 differentiation of T cells, +/- selection etc

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FA 2020 - p101 Functions of natural killer cells / major functions of B/T cells

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FA 2020 - p100 MHC 1 & 2, HLA subtypes

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FA 2020 - p99 Innate vs adaptive immunity

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FA 2020 - p98 Spleen and thymus

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FA 2020 - p97 lymphatic drainage

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FA 2020 - p96 lymphoid structures

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USMLE Step 1 review #24 - Microbiology only

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Easily confused medications

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Reading First Aid 2020

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USMLE Step 1 review #23

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NBME sample questions - Behavioral sciences

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USMLE Step 1 review #22

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USMLE review #21 FACEBOOK LIVE

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USMLE Step 1 review #20

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USMLE Step 1 review #19

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Opportunistic fungi - Aspergillus fumigatus

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Cutaneous mycoses - Dermatophytes

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Cutaneous mycoses - Sporothrix schenckii

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Cutaneous mycoses - Malessezia furfur

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Systemic mycoses - Paracoccidioides brasiliensis

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Systemic micoses - Blastomycoses dermatitidis

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Systemic mycoses - Coccidiodes immitis

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Systemic mycoses - Histoplasma capsulatum

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Episode 303: Spirochetes - Leptospirosis

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Spirochetes - Treponema pallidum

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Spirochetes - Borrelia burgdorferi

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Mycobacteria - Mycobacterium leprae

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Mycobacteria - Mycobacterium tuberculosis

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Gram indeterminate - Rickettsia rickettsii

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Gram indeterminate - Rickettsia prowazekii

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Gram indeterminate - Rickettsia overview

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Gram indeterminate - Mycoplasma pneumonia

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Gram indeterminate - Gardenerella vaginalis

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Gram indeterminate - Chlamydia trachomatis

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Gram negative rods - Bartonella henselae

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Gram negative rods - Pasteurella multocida

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Gram negative rods - Coxiella burnetti

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Gram negative rods - Francisella telarensis tularemia

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Gram negative rods - Brucella

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Gram negative rods - Legionella

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Episode 286: Gram negative rods - Hemophilus influenza

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Gram negative rods: Bordatella pertussis

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Gram negative bacilli - Vibrio cholera

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Gram negative bacilli - Salmonella

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USMLE Step 1 review #18 (Physiology only)

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USMLE Step 1 review #17 (Physiology only)

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USMLE Step 1 review #16

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USMLE Step 1 review #15

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Gram negative bacilli - Pseudomonas

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Gram negative bacilli - Helicobacter pylori

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Gram negative bacilli - Klebsiella, Enterobacter, Serratia

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Gram negative bacteria - Campylobacter jejuni

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Gram negative bacilli - Escherichia coli

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Gram negative bacilli - Shigella

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Gram negative bacilli - Yersinia enterocolitica & Yersinia pestis

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Gram negative bacilli - Proteus mirabilis

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Gram negative cocci - Neisseria meningitides

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Gram negative cocci - Neisseria gonorrhea

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USMLE Step 1 review # 14 (Micro only)

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USMLE Step 1 review #13

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USMLE Step 1 review #12

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Cornybacterium diphtheria

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Neisseria overview

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Actinomyces israelii

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Nocardia

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Listeria monocytogenes

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Clostridium perfringes

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Clostridium difficile

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Clostridium botulinum

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Enterococcus - E. Faecalis and E. Faecium

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Bacillus anthracis and Bacillus cereus

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Episode 255: Gram positive bacilli - Clostridium tetani

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Gram positive cocci - Staph epidermidis and Staph saprophyticus

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Gram positive cocci - Group A strep - Strep pyogenes

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Episode 252: Gram positive cocci - strep pneumonia and strep viridans

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Gram positive cocci - Group B strep, Strep agalactiae

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Gram positive cocci - Staphlococcus aureus

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USMLE Review #10

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USMLE Step 1 review #9

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USMLE Step 1 review #8

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USMLE Step 1 review #6

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USMLE Step 1 review #6 

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Episode 244 - USMLE educational objectives #3

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USMLE educational objectives #2

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Sketchy - Staphylococcus aureus

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Pediatrics / Neonatology shelf exam review session

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Episode 240 - USMLE summaries

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Reading USMLE educational objectives 2

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Reading USMLE educational objectives 1

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Decompensated heart failure

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Pathologystudent.com The three causes of portal hypertension

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FA USMLE Review - 3

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A 30-year-old woman with unsteady gait and numbness of both legs

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A 69-year-old woman with progressive difficulty of vision

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A 60-year-old man with a cough for two months

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Lightheadedness and dizziness that resolve after eating a meal

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A 16-year-old boy is undergoing evaluation for jaundice

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FA USMLE Review - 2

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FA USMLE Review - 1

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Lang biochem - Medium-Chain Acyl-CoA Dehydrogenase deficiency

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Lang biochem - Systemic primary carnitine deficiency

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Lang biochemistry - Carbohydrate metabolism review

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Lang biochem - Carbohydrate metabolism contents

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Guess the autoantibody for these conditions

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Pathologystudent.com - Zollinger Ellison syndrome

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Pathologystudent.com - Two types of gastric carcinoma

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Pathologystudent.com -The Sister Mary Joseph nodule

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Pathologystudent.com - The gist of GISTs

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Pathologystudent.com - Super short, super high yield food poisoning pearl

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Pathologystudent.com - Pseudomembranous colitis

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Pathologystudent.com - Menetrier disease

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Pathologystudent.com - Dietary influences on gastric cancer

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Pathologystudent.com - Cholera

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Pathologystudent.com - Angiodysplasia

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Pathologystudent.com - Abetalipoproteinemia

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Pathologystudent.com - What's the name of the spaghetti and meatballs yeast

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  1. Pathologystudent.com - Uremia

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Pathologystudent.com -Two ways osteoblasts make bone

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  1. Pathologystudent.com - Two types of esophageal carcinoma

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Pathologystudent.com - Two developmental neck cysts

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Pathologystudent.com - Top three renal causes of nephrotic syndrome

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Pathologystudent.com - Three similar words, three totally different cells

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Pathologystudent.com - Small round blue cell tumor mnemonic Mr. Sleep

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Pathologystudent.com - Six GI polyposis syndromes

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Pathologystudent.com - Renal cell carcinoma

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Pathologystudent.com - Remember how the glands look in different parts of the stomach

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Pathologystudent.com - PSGN mnemonic

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Pathologystudent.com - Paget disease and jigsaw puzzles

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Pathologystudent.com - Nephrotic vs. nephritic syndrome symptoms

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Pathologystudent.com - Nephrotic vs nephritic syndrome (ways to remember them)

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Pathologystudent.com - Minimal change disease

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Pathologystudent.com - Microscopic colitis

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Pathologystudent.com - Meckel diverticulum

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Pathologystudent.com - Mallory-Weiss syndrome

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Pathologystudent.com - How to study diseases - Use four categories

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Pathologystudent.com - Intestinal obstruction

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Pathologystudent.com - Small round blue cell tumor mnemonic Mr. Sleep

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Pathologystudent.com - Six GI polyposis syndromes

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Pathologystudent.com - Renal cell carcinoma

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Pathologystudent.com - Remember how the glands look in different parts of the stomach

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Pathologystudent.com - PSGN mnemonic

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Pathologystudent.com - Paget disease and jigsaw puzzles

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Pathologystudent.com - Nephrotic vs. nephritic syndrome symptoms

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Pathologystudent.com - Nephrotic vs nephritic syndrome (ways to remember them)

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Pathologystudent.com - Minimal change disease

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Pathologystudent.com - Microscopic colitis

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Pathologystudent.com - Meckel diverticulum

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Pathologystudent.com - Mallory-Weiss syndrome

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Pathologystudent.com: How to study diseases - Use four categories

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Pathologystudent.com - Hirschsprung disease

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Pathologystudent.com - Helicobacter pylori a strong little bugger

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Pathologystudent.com - Esophageal webs

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Pathologystudent.com - Esophageal causes of hematemesis

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Pathologystudent.com - Eosinophillic esophagitis

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Pathologystudent.com - Causes of peritonitis

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Pathologystudent.com - Brittle bone disease

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Pathologystudent.com - Azotemia

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Pathologystudent.com - Are hemolytic-uremic syndrome & thrombotic thrombocytopenic purpura related?

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Pathologystudent.com - Acute tubular necrosis

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Guillan-Barre syndrome

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Ornithine transcarbamoylase deficiency & hyperammonemia

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Lesions of the subthalamic nucleus & contralateral hemiballism

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Neisseria meningitidis & Waterhouse-Friederichsen syndrome

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Uncal herniation and CN3 palsy

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Lesions of the inferior frontal gyrus (expressive aphasia)

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Subacute and chronic subdural hemorrhages

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Pineal masses and Parinaud syndrome

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The BBB, dopamine and L-Dopa

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Delirium tremors and alcohol

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GLUT4 insulin-dependent glucose transporters

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Chronic pancreatitis and steatorrhea

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Fibrocystic breast changes

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Absence of uridine diphosphate glucuonyl transferase

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How excessive thyroid hormone affects the cardiovascular system

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Hunter syndrome

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Ethacrynic acid 

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Primary sclerosing cholangitis

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Donepezil

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Bupropion

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A two-year-old boy is brought to your office after his parents noticed a large abdominal mass while dressing him

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An eight-year-old girl presents to your clinic complaining of blurry vision

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An 18-year-old woman presents to the clinic with a recurrent sinus infection

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An 80-year-old man is admitted to the hospital for treatment of a burn

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A six-year-old girl has the sudden onset of swelling of her face, hands, legs, and feet

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An 84-year-old woman who resides in an assisted living facility

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resistance, pressure, flow & cardiac and vascular function curves

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Cardiac output equations

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Pathologystudent.com - A simple summary of glomerulonephritis

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Medbullets.com: Peptic Ulcer Disease

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Pathlologystudent.com - Four things that make helicobacter pylori particularly nasty

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Osmosis.org - Von Hippel Lindau disease

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Osmosis.org - Decreased fetal movement revealed an amniotic fluid volume that was lower than expected for gestational age

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Osmosis.org - An 86-year-old woman presents with elevated serum creatinine

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Osmosis.org - A 65-year old man with shortness of breath on exertion, pitting edema and crackles at the lung bases

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Osmosis.org - A 62-year-old woman has extreme weakness, stage 4 in renal disease, and it has been 6 days since her last dialysis

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Osmosis.org - A 55-year-old man comes to the office because of feeling thirsty and frequent urination for 1 week

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Osmosis.org - A 28-year-old woman comes to the office because of blood in her urine

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Osmosis.org - A 55-year-old man who has smoked for the past 35 years is experiencing seizures

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medbullets.com: lower GI bleed

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medbullets.com: upper GI bleed

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medbullets.com: crohn disease

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medbullets.com: Irritable bowel syndrome

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medbullets.com: chronic pancreatitis

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Medbullets.com: acute pancreatitis

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Reading First Aid: ejection fraction

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Reading First Aid: what is the calculation for stroke volume?

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Reading First Aid: myocardial oxygen demand

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Reading First Aid: afterload

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Reading First Aid: preload

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Reading First Aid: heart muscle contractility

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Reading First Aid: stroke volume SV CAP

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Reading First Aid: coronary blood supply

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Reading First Aid: Basic anatomy of the heart and the pericardium

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Reading First Aid: fetal post natal derivatives

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Reading First Aid: fetal circulation

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Reading First Aid: outflow tract formation and valve development

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Reading First Aid: Septation of the chambers

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Reading First Aid: cardiac looping

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Reading First Aid: heart embryology

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How does the heart deal with increased ventricular wall stress?

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Severe mitral regurgitation

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hydralazine, pricainamide, isoniazid

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What happens when you’re older and you have difficulty controlling hypertension?

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Granulomatous inflammation of the large arteries

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Try to remember the common causes of pneumonia by separating them into age groups and special groups

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Bugs that cause diarrhea: bloody diarrhea and watery diarrhea

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A nine month old girl has had two seizures in the past month. She was born at home and received no state mandated newborn screening

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A 26-year-old man who is HIV-positive has a CD4 T-lymphocyte count of 250

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A 25 year old woman comes to the physician because of a 10 year history of frequent occurrences of fever blisters

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A six-year-old boy with glioblastoma has a recurrence of the tumor despite aggressive treatment

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A 37 year-old woman comes to the physician because of a two month history of pain with movement of her hands and feet

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A 15-year-old girl is brought to the physician because of a three-week history of excessive thirst and voiding excessive amounts of urine

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A 46-year-old man comes to the physician because of a two week history of intermittent dizziness and difficulty standing up

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A 10-year-old boy is brought to the emergency department because of vomiting for six hours. He has had excessive thirst and excretion of large amounts of urine for three weeks.

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Hey 60 year old man has a five day history of productive cough and shortness of breath with exertion

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A previously healthy 36 year old man comes to the emergency department 12 hours after the sudden onset of increasingly severe abdominal pain

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The 24-year-old woman who breast-feeds her infant develops a warm painful mass and erythema of the overlying skin in the upper outer quadrant of the right breast

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A 47-year-old man comes to the physician because of a four day history of pain in his left that began when he tripped over a curb

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A 50-year-old woman with a history of ovarian cancer comes to the physician’s office because of swelling in her right leg for the past month

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A 25-year-old man is brought to the emergency department because of a one-week history of fever and cough productive of purulent sputum

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A 28-year-old who man had rheumatic fever as a child comes to the physician’s office because of fatigue and dyspnea for the past four months

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A 30 year-old man is brought to the emergency department 30 minutes after being stung by several wasps

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A full-term two week old male newborn has cyanosis

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A 45-year-old man has a left ventricular ejection fraction of 25% with diffuse hypokinesis

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A healthy 19-year-old man receives a tetanus immunization booster prior to induction into the US Marines

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An eight-year-old boy needs to be coaxed to go to school and while there often complains of severe headaches or stomach pain

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A 23-year-old man who is a graduate student comes to the physician because of a three month history of anxiety

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A 37 year-old man with pancreatic cancer is brought to the ER because of fever and muscle aches for four days

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An 18-year-old woman has gastroenteritis with nausea and vomiting and is able to ingest only small amounts of water

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A 70-year-old man is brought to the emergency department by his wife because of fever and shortness of breath for two days

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A two week old female newborn delivered at term is brought to the physician by her mother because of an increasingly severe diaper rash since birth

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A 76-year-old man comes to the emergency department because of a 12 hour history of fever and left lower quadrant abdominal pain

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A six-year-old boy is brought to the physician by his parents because of a three day history of fever, headache, and cough productive of a green, foul smelling discharge that also exits from his nose

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A 68-year-old woman has the sudden onset of weakness in her right arm and leg

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A 15-year-old girl is brought to the physician by her mother because of an eight month history of fatigue

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An 18-year-old female athlete reports easy fatiguability and weakness

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A previously healthy 32-year-old woman who works as a nurse comes to the emergency department because of a three-week history of episodes of dizziness, nausea, and profuse sweating that resolve with eating

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Hey 74-year-old man comes to the physician for a follow-up examination. He has a three month history of severe pain and swelling of the metacarpophalangeal joints, wrists elbows and knees

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Hospital discharge of a 75-year-old man is delayed due to unavailability of a bed in a nursing home

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A 24-year-old primigravid women at 28 weeks gestation has had nagging headaches a puffy looking face and swollen legs for the past week

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A five-year-old girl is brought to the emergency department because of fever and severe abdominal pain

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A full term female newborn is examined shortly after birth

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A 43-year-old woman comes to the physician because he has not had a menstrual period for three months

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A 26-year-old woman is brought to the ER three hours after ingesting approximately 50 tablets of aspirin in a suicide attempt

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A 76-year-old man with a history of prostatic hypertrophy has the recent onset of increased difficulty urinating

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A comatose 35-year-old man is admitted to the hospital after being involved in a motorcycle collision

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A 73-year-old woman comes to the physician because of a two month history of diffuse weakness and tingling of her arms and legs

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A 35-year-old man who works at a facility processing highly radioactive substances accidentally receives a high whole body dose of ionizing radiation

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A three month old male infant is brought to the physician because of recurrent viral infections and rashes over his trunk

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A 50-year-old man has had gradually progressive weakness of the hands during the past year

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A 45-year-old woman has a six month history of progressive shortness of breath on exertion

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An otherwise healthy 26-year-old woman has had petechiae on her legs during the last 24 hours

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A 30-year-old woman whose mother and grandmother have died of carcinoma of the breast refuses to have monography

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Warfarin is administered to a 56-year-old man pulling placement of a prosthetic cardiac valve

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A 10 month old girl is brought to the physician because of a two day history of diarrhea

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A 32 year-old man with non-Hodgkin’s lymphoma comes to the physician six days after finishing the initial chemotherapy regimen

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A 20-year-old woman comes to the physician because of a five year history of increasingly severe unilateral throbbing headaches

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A 40 year old man with a 20 year history of alcohol abuse is brought to the hospital by his friends because he was difficult to arouse

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A 26-year-old man with HIV infection comes to the doctor for a follow up examination

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A 58-year-old woman comes to the physician because of intermittent vaginal bleeding during the past three months

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A 17-year-old boy comes to the ER because of severe thirst, weakness and weight loss after a trip to Thailand

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A two-year-old boy is brought to the emergency department because of shortness of breath and left sided abdominal pain for three hours

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A four-year-old boy with delayed motor development and choreoathetosis

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A 37-year-old man comes to the physician because of a six month history of chest pain that occurs when he swallows food

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A five month old girl has bilateral retinoblastoma. One of the arms of chromosome 13 appears to be cut off or shortened

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832-year-old woman with schizophrenia is brought to the physician because of rapid heartbeats, sweating, muscle rigidity and confusion for one day

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A 25-year-old woman is brought to the emergency department one hour after she fainted

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A 30 year-old woman has anxiety about episodes of abdominal pain that have alternated with diarrhea and constipation over the past year

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Vascular control is studied in an intact hind extremity of an anesthetized experimental animal

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A 72-year-old man comes to the physician because of sharp pain of his right thorax for three days and a rash and a band like distribution over his right chest for one day

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Four month old boy is brought to the emergency department 30 minutes after becoming unresponsive

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A 12-year-old boy is brought to the physician by his father because of redness and swelling of his left foot for 24 hours

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What is the best way to sterilize a bedpan infected with clostridium difficile?

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A 55-year-old man who has alcoholic cirrhosis is brought to the emergency department

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Three weeks after traveling to California to study desert flowers, a 32 year old man develops fever, chest pain and sore muscles

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A 42-year-old woman with type two diabetes mellitus presents with a 2 cm ulcer on the cervix.

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A 21-year-old man is brought to the ER by friends after he drank wood alcohol

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Group B streptococcus and sepsis

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Abnormality of the mamillary bodies

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Xanthogranulomatous pyelonephritis

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Volume loss and ADH (vasopressin)

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If you get cluster headaches, you should be aware of these drugs!

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Paclitaxel is used to fight cancer by disrupting mitosis.

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Reed-Sternberg cells have an 'owl's eye appearance'.

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Main features of down stndrome (trisomy 21)

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Craniopharyngiomas: solid, cystic & calcified

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How are DPP-4 inhibitors (gliptins) used for DM 2?

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When a mother has gestational diabetes, her condition can affect her baby.

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Why would a young child not be able to break down fatty acids during a long period of fasting?

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When a patient presents to you with pain and cramping during exercise but is able to exercise after rest and ingestion of sucrose this indicates McArdle disease.

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If a patient is producing too much aldosterone and hydrogen ions are being sent out with potassium would the environment become more basic or more acidic?

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If you have a problem with the activity of glucokinase, the beta cells of the pancreas will not be able to respond to glucose and produce insulin

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Prolactinomas are treated with dopamine agonists - E.g., bromocriptine or cabergoline

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Diabetic patients should receive selective beta blockers (selective beta 1 antagonists)

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If you don’t get enough sun you might experience bone pain as a result of a problem in normal vitamin D metabolism

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If a patient comes to you with hoarseness and difficulty breathing it could be a lingual thyroid.

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MEN 1, 2A, 2B

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What are chromaffin cells?

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When the thyroid is operated on sometimes it results in hypoparathyroidism.

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This is MED SCHOOL RADIO • Problems with fructose metabolism: Essential Fructosuria and Hereditary Fructose Intolerence

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Growth hormone and Jak-Stat signaling pathway

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If an HIV patient presents with unexplained re distribution of body fat, it could be due to the HAART drugs they are taking.

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Is it OK to give bisphosphonates to patient with osteomalacia?

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Hypophosphatemia

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Clostridium difficile