Focus on Future Medicine and Genetics: Recent Episodes
ReachMD
Where will medicine be ten years from now? ReachMD explores this broad-ranging question with a look ahead to pivotal breakthroughs that will transform healthcare: conquering cancer without debilitating side effects, unleashing fat-fighting nucleic acids, advancing technologies in the operating room, and ‘switching off' obesity genes responsible for the development of chronic diseases.
Host: Mario R. Nacinovich, Jr., MSc
Guest: Paul Orchard, MD
Although it only affects about one in 18,000 people, the impacts of adrenoleukodystrophy cannot be underestimated. That’s why Dr. Paul Orchard joins Mario Nacinovich to talk about this rare—and fatal—genetic disease, why it’s often underdiagnosed and confused with other conditions, and how we can treat it once we’ve reached an accurate diagnosis.
Host: Brian P. McDonough, MD, FAAFP
Guest: Cecilia Van Cauwenberghe
What was once a sci-fi tale is now a reality, but unlike the aliens and monsters common to this genre, artificial intelligence isn’t something healthcare professionals need to fear. On the contrary, it may just be the key to unlocking new solutions in the pharmaceutical industry, as Dr. Cecilia Van Cauwenberghe explains.
Host: Matt Birnholz, MD
Guest: Peng Zhang, PhD
Oxygen: It's the third most abundant element in our universe. From healthcare to industrial needs, we know oxygen's uses to be far-reaching, but could there still be more therapeutic potential yet?
In an in-depth conversation with Dr. Matt Birnholz, Dr. Pang Zheng presents new evidence of oxygen's potential uses within the healthcare industry.
Data, artificial intelligence, and telehealth protocols are three of the biggest buzzwords in the health care industry right now, but it’s not all just hype. Dean of the Stanford School of Medicine Dr. Lloyd Minor reveals how these three elements are part of his strategic plan for advancing 21st century biomedicine and medical education.
Host: Jennifer Caudle, DO
Guest: Jean Bennett, MD, PhD
Guest: Albert Maguire, MD
Power couple Drs. Jean Bennett and Albert Maguire discuss how their new therapy for the RPE65 gene, which causes retinal blindness, was recently approved by the FDA to become the first gene therapy treatment for a genetic disease in the United States and the first worldwide treatment for inherited blindness. Not only do they delve into the mechanics of the corrected gene injection, but they also explain what this milestone means for patient eligibility and how their marriage has played a role in the success of their research partnership.
Dr. Jean Bennett is the F.M. Kirby Professor of Ophthalmology at the Perelman School of Medicine at the University of Pennsylvania, and Dr. Albert Maguire is a Professor of Ophthalmology at the Hospital of the University of Pennsylvania and Attending Physician in the Division of Pediatric Ophthalmology at Children’s Hospital of Philadelphia.
Host: David Weisman, MD
Guest: John Khoury, MD
For the first time, the FDA has approved a direct-to-consumer genetic test from 23andme that will inform patients if they are predisposed to diseases such as Parkinson’s, Alzheimer's, and Celiac Disease among others.
Proponents applaud this decision, saying this will allow for people to know their genetic health risks and be more proactive about their health. Others argue that this information doesn’t tell the whole story since predisposition doesn't reflect someone's ultimate risk or likelihood of developing a disease. What are the benefits and liabilities of consumers' access to genetic testing?
Host Dr. David Weisman, Director of Clinical Trials at Abington Neurological Associates, sits down with Dr. John Khoury, Associate Director at Abington Memorial Hospital Sleep Disorders Center, to debate the merits and pitfalls of direct-to-consumer genetic testing.
Host: Maurice Pickard, MD
Guest: Bonnie Rochman
With the ever-expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, parents’ access to this previously unknown information is altering perceptions of disability, redefining the question of what sort of life is worth living, and who draws the line. Is this technology a triumph of modern medicine or a Pandora’s box of possibilities?
Host Dr. Maurice Pickard chats with Bonnie Rochman, author of the book The Gene Machine: How Genetic Technologies are Changing the Way We Have Kids - and the Kids We Have, about the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family.
Host: Brian P. McDonough, MD, FAAFP
Dr. Brian McDonough welcomes Lee Buckler, Director, Chief Executive Officer and President of RepliCel Life Sciences based in Vancouver, BC. Mr. Buckler and his colleagues are tackling a mix of medical and cosmetic issues that include hair regeneration, repair of painful and debilitating tendon injuries and rejuvenation of damaged skin.
Host: Shira Johnson, MD
Guest: Jean Bennett, MD, PhD
There are 39 million people worldwide who are in total blindness and another 246 million with very low vision. The most frequent forms of visual impairment are caused by problems that can be corrected. Dr. Shira Johnson welcomes Dr. Jean Bennett, Professor of Ophthalmology and Cell and Developmental Biology at the University of Pennsylvania and researcher at the Children’s Hospital of Philadelphia. Dr. Bennett discusses her innovative work and research in curing blindness through gene therapy.
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Live from the Clinical Lipid Update of the National Lipid Association in Amelia Island, FL, host Dr. Alan Brown welcomes Dr. Rhoda Cooper-DeHoff. Dr. Cooper-DeHoff is an Associate Professor in the Department of Pharmacotherapy and Translational Research and Division of Cardiovascular Medicine of the Colleges of Pharmacy and Medicine at the University of Florida. She is also Associate Director of the Center for Pharmacogenomics at this institution.
Dr. Cooper-DeHoff discusses the rise of pharmacometabolomics, genomic testing, and pharmacogenetic testing in lipidology, with particular emphasis on predictive mapping for statin responses.
Host: Tim Rush
Guest: Asif Ali, MD
Most doctors have heard about telemedicine, also called telehealth and e-medicine, but few have actually seen or utilized it in practice. As technologies enabling virtual patient visits and consultations continue to improve and gain more traction by clinicians, how will American healthcare systems change?
Joining host Tim Rush to discuss the current and future impacts of telemedicine in health care is Dr. Asif Ali, Clinical Assistant Professor of Cardiology at the University of Texas Health Science Center. Dr. Ali lectures nationwide on the evolving applications of telemedicine in modern practice.
Host: Matt Birnholz, MD
Psychiatry gets a bad rep for being one of the more "technophobic" fields in clinical medicine. This negative association stems in part to the difficulty in tracking changes in mood, cognition, and certain behaviors over time. But there is a growing contingency of psychiatric clinicians who are bringing technology into this specialty to help propel standards in mental health care.
Dr. Adam Kaplin, Assistant Professor of Psychiatry at Johns Hopkins School of Medicine and Principle Psyciatric Consultant to the Johns Hopkins Multiple Sclerosis and Transverse Myelitis Centers of Excellence, joins Dr. Jennifer Caudle to discuss ways in which technological innovations can enhance psychiatric care and decrease stigma surrounding mental illness.
Host: Brian P. McDonough, MD, FAAFP
Cryotherapy, the science of freezong for medical purposes, uses extreme cold temperatures to cool down the body and has both current and emerging medical applications ranging from brain resuscitation in emergency settings to inflammation reduction in medical spas.
Host Dr. Brian McDonough sits down with science and health journalist Renee Ebersole to talk about the rise of cryotherapy, the mechanisms governing its medical utilities, and the benefits vs risks of its applications in various health settings today.
Host: Brian P. McDonough, MD, FAAFP
Guest: Sandra Gomberg
Technological advances over the past decade have rapidly changed the ways people seek, access, and respond to health care at all levels: patients self-research medical information via health websites, clinicians counsel and treat patients from remote telemedical settings, insurance companies promote patient-controlled health savings accounts, and healthcare organizations monitor internet reviews to predict future cash flow rises and falls. All of these changes point toward a consumer-driven healthcare (CDHC) model, but where will it lead?
From the Villanova Healthcare Speaker Event, host Dr. Brian McDonough talks with guest Sandra Gomberg, Chief Operating Officer at Aria Health System. They discuss ways in which medicine has adopted consumer-driven healthcare over time, and what the future holds for patients and clinicians in this system.
Host: Matt Birnholz, MD
Guest: Ronald J. Wapner, MD
Innovations in medical genetics are changing the practice of obstetrics and gynecology. With advancing knowledge of underlying genetic predispositions, doctors can provide more precisioned care plans for patients in women's health centers.
Dr. Matt Birnholz talks with Dr. Ronald J Wapner, Professor of Obstetrics and Gynecology and Director of Reproductive Genetics at Columbia University, about how the ever-changing field of medical genetics is revolutionizing OB/GYN treatment options and patient care.
Host: Matt Birnholz, MD
In the ongoing global campaign to prevent, treat, and cure HIV and AIDS, there have been countless therapeutic approaches targeting the HIV virus and everything it interacts with on the path to infection. But after decades of relentless infectivity claiming over 25 million lives, what if we could one day simply edit and delete the HIV virus right out of existence?
Joining Dr. Matt Birnholz to discuss a novel research effort to leverage gene editing technology in the fight against HIV is Dr. Kamel Khalili, Professor and Chair of the Department of Neuroscience, Director of the Center for Neuro-virology, and Director of the Comprehensive Neuro-AIDS Center at the Lewis Katz School of Medicine at Temple University.
[Read the Article]
Rates of genetic testing for BRCA1 and BRCA2 mutations have increased among younger women diagnosed with breast cancer, according to a new study. The study focused on nearly 900 women diagnosed with breast cancer at age 40 or younger. Researchers looked at rates of genetic testing, barriers to testing, and how the test results affected treatment decisions.
In 2006, the rates of BRCA testing were in the seventy percent range and by 2012 that proportion rose to ninety-five percent. While the majority of women reported being tested for BRCA 1 and 2, many were not, and a small minority reported that no one had discussed genetic risk or testing options. The study authors note that the overall goal of genetic testing is to help women make informed treatment decisions. Assessment of a young woman's genetic risk after a breast cancer diagnosis can affect treatment decisions and the results can also have health implications for her relatives.
[Watch more videos of The JAMA Report]
Host: Alicia A. Sutton
From the floors of Omnia Education's Women's Health Annual Visit in Washington DC, host Alicia Sutton interviews Dr. Joel Weinthal, Clinical Associate Professor of Pediatrics at Texas Tech University Health Sciences Center and Medical Director of the Stem Cell Transplant Laboratory at Medical City Dallas Hospital. The two discuss Dr. Weinthal's current work in regenerative medicine, the scope of clinical utilization and potential, ethical considerations, and anticipated directions for the field.
Host: Matt Birnholz, MD
From mapping AEDs on a phone app to communicating with colleagues on Facebook, technology has become an integral part of daily life. Some would even call their phones an extension of the human nervous system, as evinced by a near-constant awareness of their battery life. Yet despite this high prevalence and demand for social media in regular affairs, medicine has been slow to adopt it.
Join Dr. Matt Birnholz and Dr. Nathaniel DeNicola discuss the role of technology and social media in medicine, with particular attention to ACOG's adoption over the past 10 years.
This week, Mark and Margaret speak with Dr. Eric Green, Director of the National Human Genome Research Institute at the National Institutes of Health, the world's largest organization dedicated solely to genomics research. Dr. Green was on the team that mapped the human genome and talks about new initiatives at NIH to create better platforms for storing and sharing big data in this new era of scientific research.
This week, Mark and Margaret speak with Dr Kenneth Brigham, cofounder and past director of the Emory/Georgia Tech Predictive Health Institute, on the future of predictive health. They discuss the use of genomics, biometrics, and nanotechnology to identify disease risks early in life and perhaps prevent the future onset of disease.
Guest: Schlomo Mor-Yosef, MD, MPA
Host: Matt Birnholz, MD
What lessons can we learn from a state-of-the-art medical center in Jerusalem? Dr. Shlomo Mor-Yosef, director general of Hadassah Medical Center, talks with host Dr. Matthew Birnholz about the day-to-day workings of this level 1 trauma center on contentious ground.
Guest: Andrew Schafer, MD
Host: Bruce Japsen
Though practicing clinicians have long played an important role in medical research and advancing medical treatments, their position in the laboratory has changed dramatically in recent years. But is the future of the physician-scientist in danger? Dr. Andrew Schafer, chairman of the department of medicine at Weill Cornell Medical College, and physician-in-chief of the New York-Presbyterian Hospital Weill Cornell Medical Center in New York, tells host Bruce Japsen about a critical issue facing medicine in the dramatic decrease in the number of practicing physicians involved in conducting research.
Guest: Richard Sayre, PhD
Host: Bruce Japsen
While researchers in labs across the country work on genetic engineering of stem cells or pharmaceutical innovation from molecule based drugs from chemicals, patients and their doctors should not forget about plants. Dr. Richard Sayre, director of the Enterprise Rent-A-Car Institute for Renewable Fuels at the Donald Danforth Plant Science Center in St. Louis, tells host Bruce Japsen about how a common plant may unlock a treatment for deadly malaria.
Guest: Joel English
Host: Bruce Japsen
Whether it's a surgery webcast or a new marketing plan rolled out on Twitter or YouTube, the traditionally conservative healthcare industry is reaching out through new marketing venues to promote hospitals and physician services. Joel English, managing director of healthcare marketing firm BVK, Inc., and a board member of the Society for Healthcare Strategy and Market Development, explains to host Bruce Japsen about social media, its place in today's healthcare system and whether it's here to stay.
Guest: Bruno V. Gallo, MD
Host: Shira Johnson, MD
Deep brain stimulation is used for movement disorders but can it be used for depression, addiction and chronic pain? Dr. Bruno Gallo, an assistant professor of neurology at the University of Miami in Miami, Florida joins host, Dr. Shira Johnson to talk about the promise that deep brain stimulation can provide to patients when medication is not taking care of their symptoms. The two also discuss the bright future that brain stimulation has when it comes to curing other diseases.
Host: Lee Freedman, MD
Guest: Michael Hildebrand, PhD
Researchers have discovered a CATSPER gene mutation that may lead to development of a male infertility treatment, as well as a male contraceptive. Are we really another step closer to developing a male contraceptive, and when might an oral contraceptive be available for men? Join host Dr. Lee Freedman as he talks with Dr. Michael Hildebrand, fellow in the department of otolaryngology at the Carver College of Medicine, University of Iowa, about this exciting new genetic discovery, and how it might lead to the development of a male contraceptive.
Guest: John Whapham, MD, MS
Host: Mark Nolan Hill, MD
Somewhere in between the fields of neurology and neurosurgery, we find physicians using less invasive techniques to perform procedures that could be classified as endovascular neurosurgery, or interventional neuroradiology, or more plainly, as neurology practiced through catheters. Dr. John Whapham, a neurointerventionalist and an assistant professor in the departments of neurology and neurological surgery at the Loyola University Chicago Stritch School of Medicine, explains how this area of practice has evolved in recent years, and previews what's in store for the future of this discipline, blending expertise across multiple specialties. Dr. Mark Nolan Hill hosts.
Guest: Patrick Schlievert, PhD
Host: Lee Freedman, MD
HIV research has encountered quite a few setbacks, especially with attempts to create an HIV vaccination. But topical microbicides made from glycerol monolaurate, commonly found in some foods and cosmetics, are showing some promise. What mechanisms of microbicides may help successfully prevent infection, including HIV and other sexually transmitted infections? Dr. Patrick Schlievert, professor of microbiology and immunology at the University of Minnesota Medical School, explains the exciting potential of topical microbicides for preventing the transmission of sexually transmitted infections and HIV. How soon might one of these topical microbicides be available, if they are further proved to have efficacy? Dr. Lee Freedman hosts.
Guest: Savio Woo, PhD
Host: Lee Freedman, MD
Although gene therapy has encountered a few significant setbacks in its two-decade history, it has recently demonstrated several notable successes. What conditions have been successfully treated with gene therapy, and might gene therapy some day be used to treat cancer? What are some of the obstacles we face with gene therapy? Dr. Savio Woo, professor and founding chairman of the department of gene and cell medicine at the Mount Sinai School of Medicine in New York City, discusses the potential of gene therapy with host Dr. Lee Freedman.
Guest: Gene Barnett, MD
Host: Mark Nolan Hill, MD
Even after surgery, radiation and chemotherapy, many brain tumors appear frustratingly unresponsive to treatment. Part of the trouble is that malignancies can be very difficult to reach with conventional therapy. A novel fiber-optic laser that employs heat therapy may provide unprecedented access to previously unresectable tumors, as well as added ability to focus heat directly on the tumor cells. Dr. Gene Barnett, director of the Cleveland Clinic's Brain Tumor and Neuro-Oncology Center, explores what the future may hold for this intriguing experimental technique with host Dr. Mark Nolan Hill.
Host: Cathleen Margolin, PhD
Guest: Louis Harrison, MD
Therapies that maintain or improve the quality of the patient's life are an important part of the treatment process. In cancer care, as Dr. Louis Harrison tells host Dr. Cathleen Margolin, patients who are happier with the quality of their life are often more compliant with treatment, but also may require less pain medication, and may be more able to tolerate discomfort—just a couple of the many factors that reflect their commitment to the entire treatment process. Therefore, it can be important to consider: what makes for a happier patient? Environmental, social and spiritual factors can all be a part of the equation. Beyond excellent traditional medicine, practitioners and institutions have begun to offer a variety of services, from yoga classes, to massage therapy, to a more soothing hospital environment, aimed at enhancing the patient's quality of life. Dr. Harrison, the clinical director of the Continuum Cancer Centers of New York at Beth Israel Medical Center, where the aforementioned services and more are offered at the patient's request, believes it's making a remarkable improvement in the oncology care provided at Beth Israel. Are these measures you can incorporate in your practice?
Host: Mark Nolan Hill, MD
Guest: Sam Bhayani, MD
Robotic surgery has made important in-roads into the fields of cardiac and urologic surgery. Though much of the work in urologic surgery has focused on the prostate, we're now seeing a trend toward the use of robotics in procedures to remove kidney tumors. Given the delicate nature of kidney tissue, these procedures can present considerable technical challenges, but they may also provide better outcomes for our patients with kidney cancer. Dr. Sam Bhayani, assistant professor of surgery and co-director of robotic surgery at Washington University School of Medicine in St. Louis, attributes these improvements to the better views of the tumor targets and a more efficient procedure afforded by the robotic instruments. Dr. Bhayani joins host Dr. Mark Nolan Hill to speak about current trends in robotics and renal cancers.
Guest: Robert Harman
Host: Bruce Japsen
Human stem cell treatments are only just emerging in clinical trials. but man's 'best friend' is already benefitting from pain relief and important treatments that are commercialized. And this work in dogs and cats could one day benefit human patients. Dr. Robert Harman, CEO and founder of Vet-Stem, tells the Chicago Tribune's Bruce Japsen about the latest efforts by a stem cell therapy developer to use fat cells for treatments, a therapy gaining momentum in pets and soon to be moving through clinical trials for humans.
Guest: Dan Roden, MD
Host: Bruce Bloom, DDS, JD
The greatest side effect of medications is that they often don't do what we expect them to do. Dr. Dan Roden, professor in the departments of medicine and pharmacology at Vanderbilt University School of Medicine, talks with Dr. Bruce Bloom about variability in response to drugs. Genetic components are just one of many reasons patients respond differently. Dr. Roden also discusses his specific work with customizing treatment for patients with arrhythmias based upon the disease mechanism.
Guest: Todd Feinman, MD
Host: Jennifer Shu, MD, FAAP
Clinical guidelines are available in abundance, through peer-reviewed medical journals, library-based databases and evidence-based reports. But these guidelines may not provide recommendations that are ideal for our patients’ individual needs. What if we could merge relevant data from a range of studies, creating instant meta-analyses tailored to our patients? Host Dr. Jennifer Shu explores this concept with Dr. Todd Feinman, practicing hospitalist at Harbor-UCLA Medical Center in Torrance, Calif., and founder of Doctor Evidence, a Web-based customizable digital database of disease treatment and drug efficacy information. Could medical organizations use similar mechanisms to develop policy statements or clinical recommendations?
Guest: Eric Bouhassira, PhD
Host: Mark Nolan Hill, MD
Scientists and medical experts hold grand ambitions for the emerging role of human embryonic stem cells in medicine. One of the first gains realized from these cells could be the production of red blood cells for transfusion, though several key obstacles remain. Host Dr. Mark Nolan Hill looks at these challenges with Dr. Eric Bouhassira, professor of stem cell biology and regenerative medicine, and director of the Einstein Center for Human Embryonic Stem Cell Research at Albert Einstein College of Medicine. How long will it be before the future of erythrocyte production becomes a reality?
Guest: Jeffrey D. Cirillo, PhD
Host: Mary Leuchars, MD
Tuberculosis affects the lives of one third of the world's population. How are newly advancing optical imaging technologies poised to help clinicians achieve more accurate diagnosis and treatment for patients with this serious disease? Tune in to hear host Dr. Mary Leuchars explore with Dr. Jeffrey Cirillo, associate professor of microbial and molecular pathogenesis at the Texas A&M Health Science Center College of Medicine, the optical imaging techniques under development to directly detect TB at low levels. Dr. Cirillo explains how the light waves can be used to detect and definitely confirm tubercolosis without invasive techniques, which currently is not possible using CT scans.
Guest: William Hanson, MD
Host: Lee Freedman, MD
Robotic appendages assisting in surgery that allow procedures to be performed on a patient by a physician on the opposite end of the globe, and machines that kill cancer cells on a molecular level--these are just two of the medical advances that are already beginning to revolutionize medicine. Dr. William Hanson, director of the surgical intensive care unit at the University of Pennsylvania Medical Center and author of the book The Edge of Medicine, surveys the technologies that will soon change the physician's landscape. Dr. Lee Freedman hosts. What ethical concerns will some of these new developments present?
Guest: Jun Ye, PhD
Host: Larry Kaskel, MD
Diagnosing life threatening diseases and other medical conditions could soon be as easy as breathing. June Ye, a physics professor at the University of Colorado-Boulder and his graduate student, Michael Thorpe, discuss their research on a technique that uses lasers to detect specific chemical compounds in the breath of patients. They explain to host Dr. Larry Kaskel the underlying mechanisms of this technology, which is known as optical frequency comb, and how that it is able to derive health information from the patient's breath. Tune in to hear how this technology, once perfected, will improve the efficiency of diagnosing and monitoring diseases, as well as save patients thousands of dollars on diagnostic testing.
Guest: Artemis Simopoulos, MD
Host: Lee Freedman, MD
The field of genetics was developing so rapidly in 1975, that the National Academy of Sciences published a set of genetic screening guidelines. These guidelines are still considered classic over three decades after their publication. Do all of the recommendations remain true today? Host Dr. Lee Freedman outlines the guidelines with guest Dr. Artemis Simopoulos, founder and president of the non-profit Center for Genetics, Nutrition and Health. Which recommendations have been adhered to, and which ones need more attention?
Guest: Peter Buerhaus, PhD, RN
Host: Susan Dolan, RN, JD
The nursing shortage is nothing new: it began as a supply side shortage in the 1990s Join host Susan Dolan and her guest, Dr. Peter Buerhaus, healthcare economist and professor of nursing at Vanderbilt University Medical Center, as they explore the history of the nursing shortage. Where we are today, and how we can prepare to minimize the looming shortage in years to come? While there are fewer vacancies in nursing today than in years past, the fact is that many nurses are retiring, schools are turning away nursing students, and, all the while, demand for nursing is steadily increasing. Listen in to find out what can be done about the predicament.
Guest: Paolo Macchiarini, MD, PhD
Host: Lee Freedman, MD
Recently, scientists were able to engineer for the first time a trachea developed from a patient's own stem cells, wherein a donor's trachea was lined with the patient's stem cells to prevent transplant rejection. Immunosuppressive therapy was not necessary, and the patient remains in good condition months after the surgery. Dr. Paolo Macchiarini, head of thoracic surgery at Hospital Clinic in Barcelona, Spain, delves into the details of this breakthrough surgery with host Dr. Lee Freedman.
Guest: J. Peter Rosenfeld, PhD
Host: Mark Nolan Hill, MD
Guest: Henry T. Greely, JD
In some ways, it sounds like a modern-day witch trial: using brain scans to detect a suspect’s first-hand recollection of an act they stand accused of committing. Some experts around the world have suggested that a test like this could hamper the efforts of those who attempt to lie their way out of trouble in court, hailing the technology as an advance potentially as important as DNA evidence. What are the legal ramifications of using this kind of technology in court, and if this test isn’t a panacea, is there another method in the forensic pipeline that could be? Host Dr. Mark Nolan Hill peers into the future of lie detection with Dr. J. Peter Rosenfeld, professor of psychology at Northwestern University, and Henry Greely, professor of law and director of the Center for Law and the Biosciences at Stanford University.
Guest: J. Peter Rosenfeld, PhD
Host: Mark Nolan Hill, MD
Guest: Henry T. Greely, JD
Neuroscientists have been working for years to find unfailing methods of lie detection, a breakthrough that could dramatically change law enforcement as we know it. One newer test aims to separate events that a suspect has witnessed from actions they have committed, and despite growing scientific suspicion of its validity, the technology is being used in India as critical trial evidence. Why would India’s court system be the first to allow the submission of evidence based on this test? Could this potentially affect the practice of lie detection in the United States and around the world? Host Dr. Mark Nolan Hill examines the scientific and legal angles of this development in India with Dr. J. Peter Rosenfeld, professor of psychology at Northwestern University, and Henry Greely, professor of law and director of the Center for Law and the Biosciences at Stanford University.
Guest: Teri Mills, RN
Host: Susan Dolan, RN, JD
Guest: Alisa Schneider, RN
What is a National Nurse? In this segment, registered nurses Teri Mills, president of the National Nursing Network Organization, and Alisa Schneider, secretary of the National Nursing Network Organization, describe the effect a National Nurse would have on the nursing profession. Ms. Schneider discusses how nurses from across the country would be involved and how the National Nurse position could help to address the nursing shortage. Ms. Schneider describes the prevention programs the National Nurse would champion, and how listeners can support the National Nurse initiative. Hosted by Susan Dolan.
Guest: Teri Mills, RN
Host: Susan Dolan, RN, JD
Guest: Alisa Schneider, RN
Is it time for nursing to have a seat at the nation's healthcare table? In this segment, registered nurses Teri Mills, president of the National Nursing Network Organization, and Alisa Schneider, secretary of the National Nursing Network Organization, describe the organization's efforts in support of a National Nurse. Ms. Mills explains the legislative history in support of a National Nurse and discusses who would serve as the National Nurse. Ms. Schneider discusses how the National Nurse role would differ from the United States Public Health Service Chief Officer position and explains the goals of the National Nurse. Hosted by Susan Dolan.
Guest: Dennis A. Steindler, PhD
Host: Leslie P. Lundt, MD
What are the barriers in science that keep us from reaching the lofty goal of limb and organ regeneration? Host Dr. Leslie Lundt is joined by Dr. Dennis Steindler, the Joseph J. Bagnor/Shands Professor of Medical Research and the executive director of the McKnight Brain Institute at the University of Florida, to learn about the work of the Regeneration Project, a partnership of the McKnight Brain Institute and the Program in Stem Cell and Regenerative Medicine at the University of Florida. Find out how the study of salamanders could lead us to the next steps in regeneration.
Guest: Mark Denison, MD
Host: Mark Nolan Hill, MD
Understanding the mechanisms through which animal viruses mutate and emerge as human pathogens helps us to predict and restrict the impact of natural pandemics and intentionally spawned virulent diseases. Toward this end, the cultivation of complex synthetic viruses is a promising area of research. Looking into the future, will these efforts allow us to subdue viruses in animals before they emerge in humans? In the context of the work of his research team to synthesize a bat coronavirus to better understand the origins of the severe acute respiratory syndrome (SARS) outbreak in 2003, Dr. Mark Denison, professor of pediatrics and associate professor of microbiology and immunology at Vanderbilt University School of Medicine, explores this question with host Dr. Mark Nolan Hill.
Guest: James M. Galloway, MD
Host: Maurice Pickard, MD
What is the role of physicians in a community effort to improve the health of its citizens? Dr. James Galloway, assistant US Surgeon General, rear admiral in the United States Public Health Service and regional health administrator in Region V, Chicago, is leading a community health initiative called 'Building a Healthier Chicago.' Joined by the American Medical Association, the Chicago Department of Public Health and many smaller community organizations, this program takes a collaborative community approach towards urban wellness. Find out the physician's role in this effort and how the utilization of medical students is a critical part of this prevention model.
Guest: James M. Galloway, MD
Host: Maurice Pickard, MD
"Building a Healthier Chicago" is a collaborative initiative to build a model community-wide partnership for health promotion that can be replicated nationwide. Join host Dr. Maurice Pickard as he interviews Dr. James Galloway, assistant US Surgeon General, rear admiral in the US Public Health Service and regional health administrator in Chicago's Region V. They talk about this proactive healthcare model that ultimately aims to prevent chronic disease across the country.
Guest: Nicholas Kotov, PhD
Host: Jason Birnholz, MD
Dr. Nicholas Kotov, a professor within the chemical, material science and biomedical engineering departments at the University of Michigan, describes to host Dr. Jason Birnholz the technology underlying fabrics that can detect blood and monitor health. Dr. Kotov explains how ordinary cotton, dipped in a solution of carbon nanotubes and a solution of polymers, can conduct enough power to illuminate a diode device. Tune in to hear how this conductivity is put to use, and the applications for transforming clothing into a data device that provides health-related information.
Host: Cathleen Margolin, PhD
Guest: Woodson Merrell, MD
When clothing designer Donna Karan lost her husband and then her best friend to cancer, she felt frustrated with the limitations of the strictly Western style of medical care they had received. Ms. Karan recognized the important contributions of science from Western medicine, but she also believed that healing comes from spiritual and alternative means. Her desire to combine the best of Eastern and Western healing methods resulted in an $850,000 grant to Beth Israel Medical Center's Continuum Center for Health and Healing and department of integrative medicine in New York City. Dr. Woodson Merrell, chair of the department of integrative medicine, explains how integrative therapies are being interwoven with care strategies for complex medical cases and explores the potential of integrative medicine, as well as research into these therapies and what would lead to their taking hold at more hospitals across the country. Dr. Cathleen Margolin hosts.
Guest: Abraham Katzir, PhD
Host: Jason Birnholz, MD
Lasers may provide a means of closing surgical incisions that is better than traditional methods in terms of infection risk, time, and scarring. Dr. Abraham Katzir, professor of applied medical physics at Tel Aviv University, and a pioneer of this technique, explains to host Dr. Jason Birnholz how the Applied Physics Group at Tel Aviv University was able to develop a device that could control the temperature of the laser, to bond tissue without doing damage. Dr. Katzir outlines how surgeons would use the device, the current human applications, and the potential application of this device on all kinds of human tissues, including the retina, blood vessels, and skin. Tune in to hear how laser welding could replace the thread for closing external and internal wounds.
Guest: Philip Newbold
Host: Bruce Japsen
Why should healthcare businesses embrace innovation? From hospitals to doctors' offices, according to Philip Newbold, president and chief executive of Memorial Hospital and Health System in South Bend, Indiana, thinking toward new ideas, new tools, and new methods is crucial to a healthy organization and a healthy community. Mr. Newbold talks with host Bruce Japsen about how a mindset of innovation can be fostered, and how new thinking can invigorate healthcare organizations.
Guest: Samuel Gandy, MD
Host: Lee Freedman, MD
We know genetic mutations can cause Alzheimer's disease, so what possibilities are there for intervention to prevent patients from developing Alzheimer's, thanks to genetic discoveries? What strategies are being used to treat Alzheimer's, and which ones might be applied in the near future? Dr. Samuel Gandy, professor and director of the Farber Institute for Neurosciences at Thomas Jefferson University, discusses cognitive benefits of Alzheimer's disease medications. Dr. Lee Freedman hosts.
Guest: Samuel Gandy, MD
Host: Lee Freedman, MD
What medications are approved for the treatment of Alzheimer's disease? Dr. Samuel Gandy, professor and director of the Farber institute for neurosciences at Thomas Jefferson University, discusses state of the art pharmacologic treatments for Alzheimer's disease with host Dr. Lee Freedman. What are the benefits to each medication, and how can physicians prevent side effects from these medications? How do diet and lifestyle influence the condition?
Guest: Peter Scheidt, MD, MPH
Host: Jennifer Shu, MD, FAAP
From the air our children breathe to the food they eat, to where and how they live, the environments in which they grow affect their development and lifelong health. The National Children’s Study, undertaken by the National Institute of Child Health and Development (NICHD), is a large longitudinal investigation of these environmental influences, tracking participants from birth through early adulthood. Dr. Peter Scheidt, medical officer and co-director of the National Children’s Study at the NICHD, explains how the findings might impact patient care and offers an estimate of when we can expect to see the first significant results. If you have patients who may be interested in participating, how can you refer them for enrollment? Dr. Jennifer Shu hosts.
Guest: Peter Scheidt, MD, MPH
Host: Jennifer Shu, MD, FAAP
The National Children’s Study will follow the health and development of more than 100,000 children across the United States, starting from before birth until age 21. What do you need to know about this ambitious federally financed project? Dr. Peter Scheidt, medical officer and co-director of the National Children’s Study at the National Institute of Child Health and Human Development, provides the details on this large-scale project: what are its main goals, how is it organized, and what factors will the study examine? Dr. Jennifer Shu hosts.
Guest: Justin Sanchez, PhD
Host: Larry Kaskel, MD
Dr. Justin Sanchez explains to host Dr. Larry Kaskel the latest research regarding neuroprosthetics. These prosthetics directly interface and decode brain communications. The greatest development arises in utilizing smart prosthetics called "brain chips" that learn with the patient overtime, and someday may be used routinely to help paralyzed patients control prosthetic limbs with their thoughts. Dr. Sanchez outlines the underlying mechanisms of these devices and the current research within humans. Tune in to hear how these brain-machine interfaces are being used to control prosthetics, and the potential applications to cure diseases such as epilepsy, addiction and Alzheimer's.
Guest: Scott Riccio
Host: Bruce Bloom, DDS, JD
Guest: Phil Schein, MD
Translation for cancer therapeutics is taking too long and costing too much, according to Dr. Philip Schein, visiting professor in cancer pharmacology at the University of Oxford in England and leading international authority in the treatment of cancer. How can we improve in the future? Join host Dr. Bruce Bloom's conversation with Dr. Schein and Scott Riccio, founder and director for Accelerate Progress, a not-for-profit "action-tank" focused on bringing new promising and potentially lifesaving therapies to cancer patients, about why and how we should truncate the lengthy approval process and decrease the costs of bringing new therapeutics to market.
Guest: Scott Riccio
Host: Bruce Bloom, DDS, JD
Guest: Scott Gottlieb, MD
While new science continues to evolve the development of drugs and cures, the scientific principals we use to evaluate the drugs is arguably obsolete. Host Dr. Bruce Bloom is joined in this segment by Scott Riccio, founder and director for Accelerate Progress, a not-for-profit "action-tank" focused on bringing new promising and potentially lifesaving therapies to cancer patients, and Dr. Scott Gottlieb, a practicing physician and resident fellow at the American Enterprise Institute (AEI). Listen in to learn how clinical trial models might be changed to better evaluate the success of new drugs that target subsets of the population with certain cancers, and expedite translatable cures.
Guest: Paul Holman, MD
Host: Mark Nolan Hill, MD
Many of our patients who suffer from significant back pain put off surgery as long as they can, relying primarily on medical and physical therapy while hoping to avoid an elaborate operative procedure. Yet as with so many areas of medicine today, minimally invasive techniques are providing new options for patients with back pain, and others who face spine surgery. As with all new procedures, we have to ask, What are the fundamental risks and rewards? Dr. Paul Holman, a neurosurgeon for the Methodist Neurological Institute at the Methodist Hospital in Houston, hones in on key features of the newest approaches to minimally invasive spinal surgery: the expanding range of patients who are candidates for these procedures, common complications and the evolving technology that makes this all possible. Dr. Mark Nolan Hill hosts.
Host: Mark Nolan Hill, MD
Guest: Randi Hagerman, MD
Diagnosis of the genetic disorder Fragile X syndrome can be devastating for our young patients and their families, knowing that both the patient and their elders can be affected by this condition. Should we expand current screening measures for Fragile X? As clinicians, how do we guide patients and their families through this process of understanding their diagnosis? Dr. Randi Hagerman, professor and endowed chair of Fragile X research, and medical director of the Medical Investigation of Neurodevelopmental Disorders (MIND) Institute at the University of California, Davis School of Medicine, joins host Dr. Mark Nolan Hill to talk about the nuances of this genetic condition.
Host: Mark Nolan Hill, MD
Guest: Randi Hagerman, MD
We are rapidly learning more about the genetic disorder Fragile X syndrome, and a series of conditions related to Fragile X. We're also seeing great progress in promising therapies under investigation. How will these therapies, along with other treatment strategies, improve the lives of children and families affected by Fragile X and related conditions? Who should supervise care, and should treatment for children be coordinated with care of potentially affected relatives? Dr. Randi Hagerman, professor and endowed chair of Fragile X research, and medical director of the Medical Investigation of Neurodevelopmental Disorders (MIND) Institute at the University of California, Davis School of Medicine, shares her expansive expertise on Fragile X syndrome and associated conditions with host Dr. Mark Nolan Hill. If a child is diagnosed with Fragile X, is genetic screening inevitably warranted for parents and grandparents?
Guest: Robert Klitzman, MD
Host: Maurice Pickard, MD
Dr. Robert Klitzman, Associate Professor of Clinical Psychology at Columbia speaks about the need for more genetic counselors to help with families of Huntington's disease, breast cancer, alpha-1 antitrypsin deficiency and familial polyposis. People can order genetic testing and disease ancestry search directly on the internet. Many physicians have not been able to keep up with developments of the genome but will be asked to be knowledgeable about this exploding field. Dr. Maurie Pickard hosts.
Guest: Robert Klitzman, MD
Host: Maurice Pickard, MD
Dr. Robert Klitzman, associate professor of clinical psychology at Columbia University, discusses how to prepare patients and their families to deal with the complex issues that arise in families that have inherited Huntington's disease. Join host Dr. Maurice Pickard for this important discussion.
Host: Mark Nolan Hill, MD
Guest: Joseph Muenzer, MD
Previously, patients could only receive palliative care for symptoms associated with Hunter syndrome, a rare but serious genetic disorder that inhibits the body’s ability to break down specific complex carbohydrates. Now, a new enzyme therapy is making it possible to prevent Hunter syndrome manifestation, typically occurring as early as year two, which dramatically improves long-term quality of life. How quickly do patients show improvement with enzyme therapy? What are the most common side effects? Join host Dr. Mark Nolan Hill for an interesting conversation with Dr. Joseph Muenzer, professor of pediatrics and genetics at the University of North Carolina School of Medicine, and one of the world’s leading experts on Hunter syndrome.
Host: Mark Nolan Hill, MD
Guest: Joseph Muenzer, MD
Hunter syndrome is a rare but serious genetic disorder that inhibits the body’s ability to break down specific complex carbohydrates. Initial onset symptoms include inguinal hernias, recurrent otitis, and the common cold, frequently manifesting concurrently as part of a multi-system failure sometime after the first year of life. Because many of these symptoms are common in infants, physicians often do not suspect Hunter syndrome, yet treatment for the disease is much more effective when administered early in its progression. How can we minimize the delay typically associated with diagnosis of Hunter syndrome? Dr. Joseph Muenzer, professor of pediatrics and genetics at the University of North Carolina School of Medicine, and one of the world’s leading authorities in Hunter syndrome research, joins host Dr. Mark Nolan Hill to share his expertise.
Host: Mark Nolan Hill, MD
Guest: Joseph Muenzer, MD
Hunter syndrome is a rare but serious genetic disorder that inhibits the body’s ability to break down specific complex carbohydrates. What are the prinicipal symptoms that would lead a primary care physician to consider Hunter syndrome? Dr. Joseph Muenzer, professor of pediatrics and genetics at the University of North Carolina School of Medicine, and one of the world’s leading authorities in Hunter syndrome research, joins host Dr. Mark Nolan Hill to share his expertise.
Guest: David Wright, MD
Host: Larry Kaskel, MD
How do new devices get into clinical settings? Join host Dr. Larry Kaskel speak with Physician and Inventor Dr. David Wright about the challenges in bringing new medical technologies to the clinical setting.
Guest: Justin Barnes
Host: Michael Benson, MD
Those of us old enough to remember Stanley Kubrick’s blockbuster movie, 2001: A space odyssey, are likely to be at least a little concerned about the growth of the electronic medical record. In the movie, the spaceship’s computer ran amuck and started killing off the astronauts. Salvation could only be achieved through unplugging the machine. Is this cautionary tale an allegory for our times? What does the future hold for the EMR? Our guest today is Justin Barnes who is Vice President Marketing, Corporate Development and Government Affairs. He has testified before Congress and the Administration 7 times in the past two years. Among his many committee appointments include service on the privacy expert panel of the Certification commission for Healthcare Information Technology. Today we will be discussing the future of the Healthcare Information Technology industry.
Host: Michael Greenberg, MD
Guest: Hugh Rienhoff, MD
Dr. Michael Greenberg speaks with Dr. Hugh Rienhoff about www.mydaughtersdna.org, a website he created to help children with rare or difficult-to-diagnose genetic diseases find proper diagnoses and help.
Guest: Bill Crounse, MD
Host: Larry Kaskel, MD
Our guest, Dr. Bill Crounse, Senior Director, Microsoft Worldwide Health talks with host Larry Kaskel about 5 emerging trends in healthcare technology. How will these trends affect you in your role as a healthcare provider?
Guest: Bill Crounse, MD
Host: Larry Kaskel, MD
Dr. Bill Crounse, Senior Director, Microsoft Worldwide Health joins host Dr. Larry Kaskel for an in-depth look at the many technological advances available now and in the future to help us better manage healthcare communications and operations.
Host: Bruce Bloom, DDS, JD
Guest: David Teachey, MD
Dr. David Teachey, a practicing pediatric hematologist-oncologist, a world class laboratory and clinical researcher and an Instructor in the Department of Pediatrics, Division of Oncology, at the Children’s Hospital of Philadelphia discusses his new research repurposing pharmaceutical and botanical medicines for diseases like Lupus and ALPS.
Host: Bruce Bloom, DDS, JD
Guest: David Teachey, MD
Dr. David Teachey, a practicing pediatric hematologist-oncologist, a world-class laboratory and clinical researcher and an Instructor in the Department of Pediatrics, Division of Oncology, at the Children’s Hospital of Philadelphia discusses his research breakthrough in treating Autoimmune Lymphoproliferative Syndrome.
Host: Bruce Bloom, DDS, JD
Guest: David Teachey, MD
Dr. David Teachey, a practicing pediatric hematologist-oncologist, laboratory and clinical researcher, and instructor in the department of pediatrics, division of oncology, at the Children’s Hospital of Philadelphia, explains to host Bruce Bloom his breakthrough research that may resolve symptoms for children saddled with the rare genetic disorder, Autoimmune Lymphoproliferative Syndrome.
Guest: Harlon Wilson, MS
Host: Susan Dolan, RN, JD
Join Harlon Wilson, President and CEO of Medical Animatics, as he discusses the uses of cutting-edge 3-D modeling and animation for physicians, researchers, medical device companies, the pharmaceutical industry and the world of sports.
Guest: Harlon Wilson, MS
Host: Susan Dolan, RN, JD
Join Harlon Wilson, President and CEO of Medical Animatics, discuss how cutting-edge 3-D modeling and animation can educate patients and save physicians time and money.
Guest: Alejandro Gandsas, MD
Host: Danny Petrasek, MD, PhD
Join Dr. Petrasek as he speaks with Dr. Alejandro Gandsas from Baltimore's Sinai Hospital about modern trends in utilizing remote-controlled telemedical robots on the wards. Nicknamed Bari for the bariatric surgery Dr. Gandsas practices, the RP-7 Remote Presence Robotic System by InTouch Technologies is one of a number of robotic devices finding their way into the medical world.
Guest: James Marcin, MD
Host: Shira Johnson, MD
Dr. Shira Johnson interviews Dr. James Marcin, Director of Pediatric Intensive Care and Telemedicine expert on issues involving HIPPA, state legislation and licensure aspects for conducting telemedicine.
Guest: James Marcin, MD
Host: Shira Johnson, MD
Join Dr. Shira Johnson and her guest Dr. James Marcin, Director of Pediatric Intensive Care and Telemedine Center at UC Davis to hear about the financial aspects of Telemedicine.