Pediatrics: Recent Episodes
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Guest: Andrew Goldstone, M.D., Ph.D.
On this episode of Advances in Care, host Erin Welsh talks to Dr. Andrew Goldstone, pediatric cardiac surgeon at NewYork-Presbyterian and Columbia, about the groundbreaking heart transplant that saved the lives of three separate children. It was the first time doctors at NewYork-Presbyterian Morgan Stanley Children’s Hospital performed a split-root domino partial heart transplant. In this procedure, one child was transplanted with a new heart and their original heart was used to donate living pulmonary and aortic valves to two separate recipients in need.
Dr. Goldstone, his colleague Dr. David Kalfa, and the rest of the team at NewYork-Presbyterian and Columbia had previous experience with a handful of domino partial heart transplants where one patient is transplanted with a new heart and another receives a valve from the explanted heart. Those experiences helped prepare for the split-root domino, which took nearly 24 hours of extremely coordinated care. In addition to their efforts to increase the number of domino heart transplants being done, physician-researchers at the institution are leading new studies that are also helping improve living valve procurement and storage, allowing more children to receive heart valves that will grow with them and require less surgeries.
© 2025 …
Guess what? The CDC's Advisory Committee on Immunization Practices had a unanimous vote in favor of a preferential recommendation of vaccines for the cool adults who are 65 and older—one of these options is adjuvanted influenza vaccines.1 Talk about a milestone in the world of public health! Now the burning question is why on earth did they decide on adjuvant vaccines? Let's unravel this immunization mystery together, shall we?
Reference:
- Grohskopf LA, Blanton LH, Ferdinands JM, Chung JR, Broder KR, Talbot HK, Morgan RL, Fry AM. Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices - United States, 2022-23 influenza season. MMWR Recomm Rep. 2022 Aug 26;71(1):1-28. doi: 10.15585/mmwr.rr7101a1
USA-CRP-23-0037 12/23
Guest: Jordan Orange, M.D., Ph.D.
Guest: Joshua Milner, M.D.
Guest: Eric Silver, M.D.
Guest: Steven Lobritto, M.D.
On this episode of Advances in Care, host Erin Welsh explores the story behind the GUARDIAN study, where thousands of newborn babies have been screened against rare disease by sequencing their genes, and looking for more conditions than any of the current standard screening panels. First, she hears from Dr. Jordan Orange, Physician-in-Chief at Morgan Stanley Children’s Hospital at NewYork-Presbyterian and Columbia, about why genetic testing is a promising way of not only catching treatable rare diseases in infants, but also expanding health equity and medical resources to marginalized populations.
Erin also hears from Dr. Josh Milner, a pediatric immunologist who treated a patient with a rare form of SCID, or severe combined immune deficiency, also known as bubble boy disease that was detected in the GUARDIAN screening panel. SCID is a disease that typically occurs in 1 of 50,000 babies. But GUARDIAN caught two cases within the first 10,000 babies involved in the program, indicating that the rate of the disease might be higher than expected, and that the most accurate way to detect is through genetic screening.
Dr. Steven Lobritto, a pediatric gastroenterologist, also weighs in on how genetic screening can help identify Wilson’s disease, a copper storage …
Guest: Jonathan Strober, MD
Misinterpreted symptoms and limited access to treatment can make it difficult to manage myasthenia gravis among adolescents and young adults. Join Dr. Jonathan Strober as he explains how we can address gaps in care for this population. Dr. Strober is a Professor of Neurology at the University of California, San Francisco and the Director of the Neuromuscular Clinic at UCSF Benihoff Children’s Hospital.
Guest: John F. Brandsema, MD
As patients with Duchenne muscular dystrophy (DMD) age, their treatment regimens, considerations, and goals change. That’s why Dr. John Brandsema is here to talk about how we can best treat and support patients with DMD throughout their entire care journey. Dr. Brandsema is the Neuromuscular Section Head at the Children’s Hospital of Philadelphia.
Guest: John F. Brandsema, MD
Between 60 and 70 percent of patients with Duchenne muscular dystrophy (DMD) also have a diagnosable neurobehavioral phenotype like autism, ADHD, and anxiety. Here to talk about these common neurobehavioral issues in patients with DMD and how we can manage them is Dr. John Brandsema, Neuromuscular Section Head at the Children’s Hospital of Philadelphia.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: John F. Brandsema, MD
The gene therapy delandistrogene moxeparvovec was recently approved for patients with Duchenne muscular dystrophy (DMD) who are at least 4 years old. This expanded approval is based on the efficacy and safety results from the EMBARK trial. Joining Dr. Charles Turck to break down those key findings and the implications of this advancement in DMD treatment is Dr. John Brandsema. Dr. Brandsema is the Neuromuscular Section Head at the Children’s Hospital of Philadelphia, where one of the clinical trials for this gene therapy took place.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Nadia Merchant, MD
Guest: Melody Shi, MD
Guest: Despoina Galetaki, MD
Steroids are one of the main treatments for patients with Duchenne muscular dystrophy (DMD), but prolonged steroid use can come with many endocrine side effects, like weight gain, insulin resistance, and adrenal insufficiency. To learn more about these endocrine complications and surveillance, a recent survey was conducted, and here to share the results with Dr. Charles Turck are study authors Drs. Nadia Merchant, Melody Shi, and Despoina Galetaki.
Host: Jody Takemoto, PhD
Guest: Donald Y. Leung, MD, PhD
There’s currently no way of knowing who’s going to develop a food allergy and who isn’t, which means early treatment or even prevention can't begin. But that might all change based on a recent study, which found that skin biomarkers may be able to predict the development of food allergies in pediatric patients. Here with Dr. Jody Takemoto to talk about these findings and their potential implications on food allergy care and prevention is Dr. Donald Leung, Head of Division of Pediatric Allergy and Immunology at National Jewish Health in Denver, Colorado.
Host: Teresa K. Tarrant, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Peter E. Newburger, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Teresa K. Tarrant, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Jolan Walter, MD, PHD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Peter E. Newburger, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Jacob R. Bledsoe, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Peter E. Newburger, MD
WHIM syndrome is a rare, inherited, combined immunodeficiency disease caused by reduced mobilization and trafficking of white blood cells from the bone marrow due to over-signaling of the CXCR4/CXCL12 pathway. WHIM syndrome is named for its four common clinical findings. The diagnostic challenges arise because not all symptoms are required for a diagnosis and all of them do not appear at the same time. Patients have deficient blood levels of neutrophils (neutropenia) and lymphocytes (lymphopenia), which results in frequent, recurrent infections. Affected individuals are particularly susceptible to human papillomavirus (HPV), which can cause skin and genital warts and potentially lead to certain types of cancer. Our program goal is to identify risk factors associated with WHIM syndrome, focusing on making an earlier diagnosis that can impact long-term outcomes, timely treatment options and ultimately improved quality of life for patients.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Lauren Treat, MD
Guest: Wendy Gaultney, MD
Children who have neurological disorders and experience pain are often not able to articulate how their pain affects them. That’s why it’s important for clinicians to understand the brain’s role in the experience of pain and how to help these patients and their families navigate their pain. Joining Dr. Charles Turck to share best practices for counseling and treating pain in children with neurological disorders are Drs. Lauren Treat and Wendy Gaultney, who presented a session on this topic at the 2024 American Academy of Neurology Annual Meeting.
Guest: Dena Goffman, MD
Dr. Dena Goffman believes that better maternal care requires a proactive, system-wide approach and is making her vision a reality at NewYork-Presbyterian. She focuses on implementing guidelines that standardize care across all of NewYork-Presbyterian’s hospitals. Dr. Goffman has also aided in FDA approval and adoption of a new, ingenious hemorrhage tool and embraced simulations to train and improve the skills of healthcare professionals throughout the labor and delivery process. Join health and science journalist Catherine Price as she speaks with Dr. Dena Goffman, Vice Chair for Quality and Patient Safety and the Associate Chief and Quality Officer for Obstetrics for NewYork-Presbyterian, about how her work has helped establish goals and quality standards for safer labor and delivery.
© 2024 NewYork-Presbyterian
Host: Omer Abdul Hamid, MD
Guest: Nancy Kuntz, MD
Guest: Migvis Monduy, MD
There are many unmet needs associated with the use of anti-inflammatory glucocorticoids when treating Duchenne muscular dystrophy, or DMD. These include multiple, often debilitating comorbidities that occur with long-term exposure. Join Drs. Hamid, Kuntz, and Monduy as they discuss key clinical trial data for a novel corticosteroid that may be a safer and possibly more effective option for patients with DMD than our current standard of care.
Host: Michael A. Levine, MD, FAAP, MACE, FACP
Host: B. Michelle Schweiger, DO, MPH
Autosomal Dominant Hypocalcemia Type 1 (ADH1) is caused by gain-of-function variants of the CASR gene encoding the calcium-sensing receptor (CaSR), resulting in hypocalcemia, inappropriately low parathyroid hormone levels, and hypercalciuria. While this has been defined and reported upon, the role CaSR plays in maintaining calcium homeostasis and the potential role it might have in different patient types (from pediatric to adult population) is not well understood clinically. Furthermore, with newly published data imminent surrounding encaleret, providers must be knowledgeable about the implications associated with the new literature and the implications it has towards the practice of hypoparathyroidism.
Host: Michael A. Levine, MD, FAAP, MACE, FACP
Host: B. Michelle Schweiger, DO, MPH
Autosomal Dominant Hypocalcemia Type 1 (ADH1) is caused by gain-of-function variants of the CASR gene encoding the calcium-sensing receptor (CaSR), resulting in hypocalcemia, inappropriately low parathyroid hormone levels, and hypercalciuria. While this has been defined and reported upon, the role CaSR plays in maintaining calcium homeostasis and the potential role it might have in different patient types (from pediatric to adult population) is not well understood clinically. Furthermore, with newly published data imminent surrounding encaleret, providers must be knowledgeable about the implications associated with the new literature and the implications it has towards the practice of hypoparathyroidism.
Host: Michael A. Levine, MD, FAAP, MACE, FACP
Host: B. Michelle Schweiger, DO, MPH
Autosomal Dominant Hypocalcemia Type 1 (ADH1) is caused by gain-of-function variants of the CASR gene encoding the calcium-sensing receptor (CaSR), resulting in hypocalcemia, inappropriately low parathyroid hormone levels, and hypercalciuria. While this has been defined and reported upon, the role CaSR plays in maintaining calcium homeostasis and the potential role it might have in different patient types (from pediatric to adult population) is not well understood clinically. Furthermore, with newly published data imminent surrounding encaleret, providers must be knowledgeable about the implications associated with the new literature and the implications it has towards the practice of hypoparathyroidism.
Host: Michael A. Levine, MD, FAAP, MACE, FACP
Host: B. Michelle Schweiger, DO, MPH
Autosomal Dominant Hypocalcemia Type 1 (ADH1) is caused by gain-of-function variants of the CASR gene encoding the calcium-sensing receptor (CaSR), resulting in hypocalcemia, inappropriately low parathyroid hormone levels, and hypercalciuria. While this has been defined and reported upon, the role CaSR plays in maintaining calcium homeostasis and the potential role it might have in different patient types (from pediatric to adult population) is not well understood clinically. Furthermore, with newly published data imminent surrounding encaleret, providers must be knowledgeable about the implications associated with the new literature and the implications it has towards the practice of hypoparathyroidism.
Host: Michael J. Thorpy, MD
Guest: Anne Marie Morse, DO
Half of children who develop narcolepsy do so before age 16. However, the majority do not get diagnosed in childhood. In fact, many children are misdiagnosed and, as a result, are medically treated for conditions they do not have. Join Drs. Thorpy and Morse as they delineate the differences between adult and pediatric narcolepsy and offer strategies to optimize treatment adherence and outcomes in children.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Jill Foster, MD
The clinical and economic burden associated with the flu is particularly heavy for our youngest patients. Learn more about this burden and how influenza vaccines can help reduce it with Dr. Charles Turck and Dr. Jill Foster, Professor in the Department of Pediatrics and the Director of the Division of Pediatric Infectious Diseases at the University of Minnesota Medical School in Minneapolis.
Guest: Kenneth Alexander, MD, PhD
Guest: Noel T. Brewer, PhD
Healthcare providers face challenges in promoting HPV vaccination, which is now recommended for children at age 9. The good news is that there are scientifically validated, effective methods for promoting HPV vaccination. Tune in to learn more about the 3-step Announcement Approach and discover strategies to address parents' hesitation and optimize cancer prevention.
Host: Jennifer Caudle, DO
Guest: Ravi Jhaveri, MD
Influenza vaccines have prevented between 39,000 and 105,000 hospitalizations and between 3,700 and 9,800 deaths each year over the last 10 years in the United States alone.1 But many challenges still exist in the traditional egg-based influenza vaccine manufacturing process. To explore how cell-based vaccines, an option that uses an alternative manufacturing approach, could help address those challenges and the overall influenza burden, Dr. Jennifer Caudle speaks with Dr. Ravi Jhaveri, Division Head of Pediatric Infectious Diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago.
References:1. Centers for Disease Control and Prevention. Past seasons estimated influenza disease burden averted by vaccination. https://www.cdc.gov/flu/vaccines-work/past-burden-averted-est.html. Accessed April 8, 2022.
USA-QIVc-23-0038 06/23
Guest: Jeffrey L. Neul, MD, PhD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Guest: Alan K. Percy, MD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Host: Alan K. Percy, MD
Guest: Jeffrey L. Neul, MD, PhD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Host: Jeffrey L. Neul, MD, PhD
Guest: Alan K. Percy, MD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Guest: Alan K. Percy, MD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Guest: Alan K. Percy, MD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Guest: Jeffrey L. Neul, MD, PhD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Guest: Jeffrey L. Neul, MD, PhD
Rett Syndrome (RTT) is an X-linked dominant genetic disease estimated to affect one in every 10,000 to 15,000 live female births across all racial and ethnic groups. It is the second most common cause of mental disability in females. RTT is associated with a spectrum of subtle symptoms, many of which manifest during specific ages during a child's development. Delayed diagnosis of RTT is very common. The inability to differentiate the subtle signs of RTT impedes a proper diagnosis and delays medical interventions desperately needed for positive patient outcomes. Recognizing the subtle symptoms and deploying the multidisciplinary healthcare team earlier is vital in improving patient quality of life and decreasing psychosocial stress. The desired outcome of this educational initiative is to help the multidisciplinary team understand the circumstances that impede an early diagnosis, improve the ability to recognize and diagnose the subtle signs and symptoms of RTT earlier, impart best practices in deploying the multidisciplinary team, and raise the awareness of current and emerging therapeutics used to manage RTT.
Host: Kara Kelly, MD
This program provides awareness of the frontline therapeutic options for pediatric patients. Though current treatments are efficacious, creating a greater understanding of optimizing care while minimizing long-term toxicity from chemotherapy and radiation is critical. This clinician educational program focuses on implementing anti-CD30 targeted therapies effectively to change the disease trajectory for pediatric high-risk cHL. It provides an understanding of the expected adverse event profile of the disease and the overlap with novel therapies as we start using these emerging strategies to maximize our outcomes for the patients.
Don’t miss two additional resources that complement this program: an interactive primary treatment dosing guide; and a patient education handout. Click the Documents tab above to access.
Host: Bradford Hoppe, MD, MPH
This program provides awareness of the frontline therapeutic options for pediatric patients. Though current treatments are efficacious, creating a greater understanding of optimizing care while minimizing long-term toxicity from chemotherapy and radiation is critical. This clinician educational program focuses on implementing anti-CD30 targeted therapies effectively to change the disease trajectory for pediatric high-risk cHL. It provides an understanding of the expected adverse event profile of the disease and the overlap with novel therapies as we start using these emerging strategies to maximize our outcomes for the patients.
Don’t miss two additional resources that complement this program: an interactive primary treatment dosing guide; and a patient education handout. Click the Documents tab above to access.
Host: Priya Soni, MD, FAAP
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Kara Kelly, MD
This program provides awareness of the frontline therapeutic options for pediatric patients. Though current treatments are efficacious, creating a greater understanding of optimizing care while minimizing long-term toxicity from chemotherapy and radiation is critical. This clinician educational program focuses on implementing anti-CD30 targeted therapies effectively to change the disease trajectory for pediatric high-risk cHL. It provides an understanding of the expected adverse event profile of the disease and the overlap with novel therapies as we start using these emerging strategies to maximize our outcomes for the patients.
Don’t miss two additional resources that complement this program: an interactive primary treatment dosing guide; and a patient education handout. Click the Documents tab above to access.
Host: Vikram Anand, MD, PhD
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Kara Kelly, MD
Guest: Bradford Hoppe, MD, MPH
This program provides awareness of the frontline therapeutic options for pediatric patients. Though current treatments are efficacious, creating a greater understanding of optimizing care while minimizing long-term toxicity from chemotherapy and radiation is critical. This clinician educational program focuses on implementing anti-CD30 targeted therapies effectively to change the disease trajectory for pediatric high-risk cHL. It provides an understanding of the expected adverse event profile of the disease and the overlap with novel therapies as we start using these emerging strategies to maximize our outcomes for the patients.
Don’t miss two additional resources that complement this program: an interactive primary treatment dosing guide; and a patient education handout. Click the Documents tab above to access.
Host: Bradford Hoppe, MD, MPH
This program provides awareness of the frontline therapeutic options for pediatric patients. Though current treatments are efficacious, creating a greater understanding of optimizing care while minimizing long-term toxicity from chemotherapy and radiation is critical. This clinician educational program focuses on implementing anti-CD30 targeted therapies effectively to change the disease trajectory for pediatric high-risk cHL. It provides an understanding of the expected adverse event profile of the disease and the overlap with novel therapies as we start using these emerging strategies to maximize our outcomes for the patients.
Don’t miss two additional resources that complement this program: an interactive primary treatment dosing guide; and a patient education handout. Click the Documents tab above to access.
Host: Eric A. F. Simões, MB, BS, DCH, MD
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Eric A. F. Simões, MB, BS, DCH, MD
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Vikram Anand, MD, PhD
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Vikram Anand, MD, PhD
Guest: Priya Soni, MD, FAAP
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Vikram Anand, MD, PhD
Guest: Priya Soni, MD, FAAP
This program discusses respiratory syncytial virus (RSV), a ubiquitous infection capable of infecting all age groups with a high probability of reinfection. However, the clinical presentation of the disease across age groups is non-specific, and clinicians often fail to identify individuals within the population at the highest risk for poor outcomes. RSV vaccination attempts have historically been unsuccessful. Multiple potential vaccines are proceeding to the late stage of development; however, there is little awareness of these potential options. This program addresses these topics, as well as vaccine hesitancy, as it is often a barrier to improving vaccination compliance, as it exists both at the provider and patient level.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Carolyn Newberry, MD
Commercially blenderized and standard tube feeding formulas are both ways we can deliver food to our patients requiring home enteral nutrition. So how do these two types of formulas stack up against one another? Find out with Dr. Charles Turck as he discusses the latest literature findings and other key considerations with Dr. Carolyn Newberry, Director of GI Nutrition at Weill Cornell Medical Center’s Division of Gastroenterology.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Osman Mohamed Elfadil, MD
Food allergies and malabsorptive conditions limit food options for patients and can lead to malnutrition if alternative sources of nutrition aren’t found. So how might peptide-based formulations fit into our management approach for these GI-compromised patients? Joining Dr. Charles Turck to break down how peptide-based formulations work to improve GI tolerance, who might benefit from them, and the latest data from clinical trials is Dr. Osman Mohamed Elfadil, Senior Research Fellow in the Division of Endocrinology, Diabetes, Metabolism, and Nutrition at the Mayo Clinic in Rochester, Minnesota.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Anna Nowak-Wegrzyn, MD
Cow’s milk protein allergy is one of the most common food allergies in childhood and can have a heavy burden on our young patients and their families. That’s why Dr. Charles Turck speaks with Dr. Anna Nowak-Wegrzyn, Director of the Pediatric Allergy Program at Hassenfeld Children’s Hospital NYU Langone, about how we can better manage these patients and address their unmet needs.
Host: Danielle Becker, MD, MS, FAES
Host: Ahmed Abdelmoity, MD
Guest: Deborah Holder, MD
Guest: John Stern, MD
Vagus nerve stimulation (VNS) therapy is an add-on neuromodulation treatment designed for adults and children diagnosed with drug-resistant epilepsy (DRE). The device delivers mild pulses to the brain through the vagus nerve to help prevent seizures before they start and help stop them if they do. Join Drs. Danielle Becker, John Stern, Deborah Holder, and Ahmed Abdelmoity as they discuss best practices for initiating, titrating, and dosing adult and pediatric patients to optimize outcomes.
Host: John Buse, MD, PhD
Guest: Silva Arslanian, MD
New research on once-daily semaglutide for adolescent patients with obesity may alter clinicians’ approach to care. What do we need to know? Dr. John Buse speaks with one of the study’s investigators, Dr. Silva Arslanian, from the University of Pittsburgh to dive into this clinical data and explore how these results may change the treatment landscape.
Host: Ross M. Maltz, MD
Guest: Shail M. Govani, MD, MSc
Guest: Nana E. Bernasko, CRNP, WHNP-BC, DNP
Guest: Shubha Bhat, PharmD, MS, BCACP
As new therapies evolve, including biosimilars, it’s important for clinicians, patients, and caregivers to understand the similarities, differences, and potential risks and benefits of these therapies. Join our panel of experts to find out more about key concepts and best practices to educate your patients.
Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA
Guest: Lauren Williams, MCN,RD,LD
Kids with dyslipidemia don’t have much different nutritional needs than other young kids their age. However, there are a few key things to be aware of. So how can clinicians meet families where they are to improve their diet? Dive into the unique needs of youth with dyslipidemia as Dr. Mary Katherine Cheeley is joined by Lauren Williams, Class II Clinical Dietician at Cook Children’s Health System.
Host: Kara B. Markham, MD
What are the essential steps in managing hemolytic disease of the fetus and newborn (HDFN)? How soon after “the cord has been cut” does newborn care transfer from the maternal-fetal medicine specialist and ob-gyn to the pediatric team? At a recent satellite symposium of the American Academy of Pediatrics, Dr. James Bussel, Dr. Kara Markham, and Bethany Weathersby presented the latest data regarding current and emerging practice patterns and highlighted the critical need for improved understanding and multidisciplinary collaboration in the area of HDFN. Tune in to hear Dr. Markham summarize how diagnosis, care, and treatment have evolved—plus insights on how these might change the way you practice.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Natalia Castillo Almeida, MD
Patients in urban communities often face challenges when accessing influenza vaccines. But there are ways we can help address those geographic and socioeconomic barriers. Joining Dr. Charles Turck to share key strategies for improving influenza vaccination rates in urban communities is Dr. Natalia Castillo, Assistant Professor in the Division of Infectious Diseases at University of Nebraska Medical Center.
Host: Jennifer Caudle, DO
Guest: Jennifer Shu, MD, FAAP
Why is are we currently facing a tripledemic? Joining Dr. Jennifer Caudle to uncover what has led to this dramatic increase in COVID-19, RSV, and the flu—and share strategies to combat this tripledemic—is ReachMD Host Dr. Jennifer Shu, a pediatrician at Children’s Medical Group in Atlanta, Georgia.
Host: Jennifer Caudle, DO
Guest: Sandra P. Reyna, MD
Spinal muscular atrophy (SMA) is a challenging rare disease that requires a diagnosis and access to treatment as early as possible. To help us understand the importance of early treatment, Dr. Sandra Reyna from Novartis Gene Therapies shares key considerations for optimizing outcomes and gives us some insight into available SMA treatment options, focusing on the gene therapy ZOLGENSMA.
© 2022 Novartis Gene Therapies, Inc.
US-ZOL-22-0129 08/22
Host: Jennifer Caudle, DO
Guest: Sandra P. Reyna, MD
Spinal muscular atrophy (SMA) is a challenging rare disease that requires a diagnosis and access to treatment as early as possible. To help us understand the importance of early treatment, Dr. Sandra Reyna from Novartis Gene Therapies shares key considerations for optimizing outcomes and gives us some insight into available SMA treatment options, focusing on the gene therapy ZOLGENSMA.
© 2022 Novartis Gene Therapies, Inc.
US-ZOL-22-0129 08/22
Host: Matt Birnholz, MD
Guest: David Canaday, MD
As we age, our immune system becomes weaker and is therefore unable to ward off infection as easily as in our younger years.1 This is particularly troublesome during flu season. In fact, the CDC’s Advisory Committee on Immunization Practices (ACIP) recently looked at flu vaccine data for adults aged 65 years and older, and they now recommend that this age group preferentially receive higher dose or adjuvanted vaccines over standard dose unadjuvanted vaccines when available.2 So what was the data that led to these updated recommendations? Joining Dr. Matt Birnholz to share those key findings and the role of adjuvanted vaccines like FLUAD® QUADRIVALENT (Influenza Vaccine, Adjuvanted) in preventing influenza in older adults is Dr. David Canaday, Professor in the Division of Infectious Diseases & HIV Medicine at Case Western Reserve University in Cleveland.
Avoid use in patients who have experienced any severe allergic reactions to any component of the vaccine. For more risk information please see below or consult the Full US Prescribing Information for FLUAD® QUADRIVALENT here.
References:
1. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis. 2002;2(11):659-666.
2. Centers for Disease Control and Prevention. Past seasons estimated influenza disease …
Host: Matt Birnholz, MD
Guest: David Canaday, MD
As we age, our immune system becomes weaker and is therefore unable to ward off infection as easily as in our younger years.1 This is particularly troublesome during flu season. In fact, the CDC’s Advisory Committee on Immunization Practices (ACIP) recently looked at flu vaccine data for adults aged 65 years and older, and they now recommend that this age group preferentially receive higher dose or adjuvanted vaccines over standard dose unadjuvanted vaccines when available.2 So what was the data that led to these updated recommendations? Joining Dr. Matt Birnholz to share those key findings and the role of adjuvanted vaccines like FLUAD® QUADRIVALENT (Influenza Vaccine, Adjuvanted) in preventing influenza in older adults is Dr. David Canaday, Professor in the Division of Infectious Diseases & HIV Medicine at Case Western Reserve University in Cleveland.
Avoid use in patients who have experienced any severe allergic reactions to any component of the vaccine. For more risk information please see below or consult the Full US Prescribing Information for FLUAD® QUADRIVALENT here.
References:
1. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis. 2002;2(11):659-666.
2. Centers for Disease Control and Prevention. Past seasons estimated influenza disease …
Host: William Mencia, MD, FACEHP, CHCP
Guest: Julie Blatt, MD
Guest: Taizo Nakano, MD
PIK3CA-related overgrowth spectrum (PROS) refers to various clinical entities that share the same pathogenetic mechanism. These disorders are caused by somatic gain-of-function PIK3CA mutations. Diagnosis of PROS is often challenging and requires DNA sequencing of the affected tissue. PIK3CA genetic mutations vary greatly depending on the tissue being tested. PROS is not considered an inherited disease.
The road to a diagnosis of a rare disease can be a long, winding process. Because of its rarity, a wide spectrum of symptoms, and disease heterogeneity, patients may feel alone and as though they are the only ones with the disease. Management of PROS currently involves symptomatic treatment of its manifestations; an unmet need exists for targeted, systemic therapies.
Currently, there is no cure for PROS. This educational activity will assist the interprofessional care team to better understand, apply, and interpret advances in current and emerging evidence that will help bridge the gap toward faster adoption into patient care.
Host: William Mencia, MD, FACEHP, CHCP
Guest: Julie Blatt, MD
Guest: Taizo Nakano, MD
PIK3CA-related overgrowth spectrum (PROS) refers to various clinical entities that share the same pathogenetic mechanism. These disorders are caused by somatic gain-of-function PIK3CA mutations. Diagnosis of PROS is often challenging and requires DNA sequencing of the affected tissue. PIK3CA genetic mutations vary greatly depending on the tissue being tested. PROS is not considered an inherited disease.
The road to a diagnosis of a rare disease can be a long, winding process. Because of its rarity, a wide spectrum of symptoms, and disease heterogeneity, patients may feel alone and as though they are the only ones with the disease. Management of PROS currently involves symptomatic treatment of its manifestations; an unmet need exists for targeted, systemic therapies.
Currently, there is no cure for PROS. This educational activity will assist the interprofessional care team to better understand, apply, and interpret advances in current and emerging evidence that will help bridge the gap toward faster adoption into patient care.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Nick Kusnezov, MD
Can you balance locum tenens with a full-time career? To answer that question, Dr. Charles Turck is joined by board-certified orthopedic surgeon, Dr. Nicholas Kusnezov, to walk us through his journey from joining the military to locum tenens.
Host: Jennifer Caudle, DO
Guest: Roni Devlin, MD
As rates of burnout continue to rise in the healthcare community, how can help our female physicians combat it? Dr. Jennifer Caudle joins Infectious Disease Specialist, Dr. Roni Devlin, to discuss how we can prevent burnout for female physicians.
Host: Jennifer Caudle, DO
Guest: Wendy Wright, DNP, FNP-BC, ANP-BC, FAANP, FAAN, FNAP
Guest: Gary Marshall, MD
It's well understood that annual vaccination is the best way to help reduce the high burden associated with influenza. And while most influenza vaccines available in the United States are produced in eggs, this presents some inherent challenges, which can lead to reduced vaccine effectiveness. Fortunately, alternative production processes can help us overcome those challenges, and to learn more, Dr. Jennifer Caudle speaks with Dr. Wendy Wright and Dr. Gary Marshall.
USA-CRP-22-0018 May 2022
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Trevor Cabrera, MD
What’s it like becoming a locum tenens physician right out of residency? Dr. Charles Turck joins Dr. Trevor Cabrera, a Board-Certified pediatrician who trained in Houston, Texas, to share his firsthand experience and offer advice for residents.
Host: Paul P. Doghramji, MD, FAAFP
Guest: Samantha Conroy, MD
Locum tenens can improve quality of care around the globe—especially in remote and underserved communities. To share how, Dr. Paul Doghramji joins Dr. Samantha Conroy, a family practice obstetrician to share her experiences working as a locum tenens obstetrician in underserved communities.
Host: Jennifer Caudle, DO
Guest: Maurice G. Sholas, MD, PhD
After years of serving the New Orleans community, one physician decided to pursue locum tenens work. Dr. Jennifer Caudle joins Dr. Maurice Sholas, a pediatric physical rehabilitation physician, to share his experiences with locum tenens and in New Orleans.
Host: Carol Wysham, MD
Guest: Jane J. Kim, M.D.
Since 2020, pediatricians have seen a rapid rise in new-onset type 1 diabetes in children. Is this due to the COVID-19 pandemic or an indirect consequence of it? To answer this question, Dr. Jane Kim, a pediatric endocrinologist at Rady Children's Hospital in San Diego, shares what kind of correlation she's seeing.
Host: Carol Wysham, MD
Guest: Jane J. Kim, M.D.
Emerging research details a rapid rise in type 1 diabetes in children amid the COVID-19 pandemic. But what's causing this to happen? To dive into why, Dr. Carol Wysham is joined by Dr. Jane Kim from the Rady Children's Hospital in San Diego.
Host: Jennifer Caudle, DO
Guest: Ashish S. Patel, MD
Treating IBD in our pediatric patients can be challenging, which is why creating a strong partnership between care teams and patients’ families is key. Fortunately, that was a central focus of the 2022 Crohn's & Colitis Congress, so to catch the latest updates and strategies for improving IBD care for pediatric patients, tune in to hear Dr. Jennifer Caudle speak with Dr. Ashish Patel.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Carlos Jesus Acuña-Villaorduña, MD
What are some of the immunologic mechanisms that alter our ability to fight off a mycobacterium tuberculosis infection—and how does this affect our immunocompromised patients? To answer this question, Dr. Charles Turck meets with Dr. Carlos Acuña-Villaorduña from the Boston University School of Medicine to discuss new insights on TB infection and immunosuppression.
Host: Rachel Caskey, MD, MAPP
Guest: Gwendolyn Ramirez
Vaccine hesitancy is a very challenging, and often tiring topic, for clinicians to address. Join Dr. Rachel Caskey in an engaging clinician-patient dialogue as she uses a dynamic and presumptive approach to overcome common vaccination challenges. What communication pearl will you use with your patients?
Host: John J. Russell, MD
Guest: Joseph E. Bavaria, MD
Featuring a wide range of disciplines and a new approach to comprehensive care, what do we need to know about the Aorta Center at Penn Medicine? Dr. John Russell is joined by Dr. Joseph E. Bavaria to dive into this aortic program and discuss a new approach to comprehensive care.
Host: Hector O. Chapa, MD, FACOG
Guest: Dani Dumitriu, MD, PhD
The COVID-19 pandemic has taken a toll on all patients, especially pregnant women. Here to walk us through her research on the pandemic's impact on the psychosocial health of mothers and the neurodevelopment of their fetuses is Dr. Dani Dumitriu, a pediatrician, neuroscientist, and pediatric environmental health scientist at Columbia University in New York.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Donald Middleton, MD
Influenza causes considerable morbidity and mortality in children. In fact, the CDC estimates that from the 2010-2011 season to the 2019-2020 season, seasonal flu-related hospitalizations among children younger than 5 years old have ranged from 7,000 to as high as 26,000 every year.1 This is a sobering reminder of the pivotal role vaccination plays in preventing influenza disease, and now, recent safety and immunogenicity data has led to the expanded age indication for the cell-based vaccine FLUCELVAX QUADRIVALENT. Explore that data and what this approval means for patients 6 months of age and older with Drs. Charles Turck and Donald Middleton.
- Centers for Disease Control and Prevention. Flu and young children. https://www.cdc.gov/flu/highrisk/children.htm. Accessed December 22, 2021
USA-QIVc-21-0169 December 2021
Host: Jacob Sands, MD
Guest: Yasmin Jayasinghe, FRANZCOG, PhD
Pediatric and adolescent oncofertility patients are cared for differently than adult patients. That’s why Dr. Yasmin Jayasinghe, Director of the Oncofertility Program at the Royal Children’s Hospital, is here to give us an overview of the available procedures for pediatric patients and the key considerations that go along with them.
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Guest: Joseph Marek, MD
Sudden cardiac death is rare in younger patients, but it remains one of the leading causes of death in young athletes. To learn more about this, Dr. Alan Brown is joined by Dr. Joseph Marek, Clinical Cardiologist and Senior Medical Director of Cardiopulmonary Service at Advocate Medical Group, to share how his foundation, Young Hearts 4 Life, is working to increase awareness for sudden cardiac arrest and provide young athletes resources.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Kathryn Gallagher, MS, RN, BSN
Guest: Kate Newcomb-DeSanto, MSN, RN, MSW
What does Penn Medicine’s newly-opened patient room facility have to offer? Dr. Charles Turck is joined by Penn Medicine Clinical Advisors Kathy Gallagher and Kate Newcomb-DeSanto to discuss the new pavilion and how it's revolutionizing patient care.
Host: Jonathan C. Routh, MD, MPH, FAAP
Guest: Benjamin M. Whittam, MD, MS, FAAP, FACS
This Expert Exchange webcast is designed to enhance clinicians’ awareness of advances in the pharmacotherapeutic armamentarium for treating NDO in the pediatric population.
View the Advances in the Treatment of Neurogenic Detrusor Overactivity Clinical Compendium here: https://cdn.reachmd.com/uploads/clinicalcompendium_ndo_v2_final.pdf
Host: Jennifer Caudle, DO
Guest: Vikram V. Bhise, MD
Pediatric multiple sclerosis (MS) occurs in more than 8,000 children in the United States alone, but there’s little data regarding these patients’ quality of life. That’s why Dr. Vikram Bhise recently conducted research to gain a better understanding of pediatric MS patients’ quality of life as they transition into adulthood. And now, Dr. Bhise joins Dr. Jennifer Caudle to share the results that were presented at the 2021 Consortium of Multiple Sclerosis Centers (CMSC) Annual Meeting.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Emily Carroll, JD, MSW
The No Surprises Act aims to protect consumers from surprise medical bills. But how exactly does it go about doing that, and what’s the current status of its implementation? Joining Dr. Charles Turck to share progress and challenges associated with the No Surprises Act is Ms. Emily Carroll, a senior legislative attorney for the American Medical Association's Advocacy Resource Center.
Host: Jennifer Caudle, DO
Guest: Sarah Ali, MD
From working in a big city to taking on an assignment in a small mountain village, Dr. Sarah Ali from the Ventura County Medical Center joins Dr. Jennifer Caudle to talk about her adventures abroad with locum tenens and share key lessons she learned along the way.
Host: John J. Russell, MD
Guest: Randy C. Miles, MD, MPH
Are enlarged lymph nodes caught on CT scans following mRNA vaccination cause for concern? Or is it just a case of incidentaloma? Joining Dr. John Russell to answer those and other key questions regarding the link between COVID-19 vaccines and abnormal mammogram findings is Dr. Randy C. Miles.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Mark Blatter, MD
Despite their crucial role in preventing seasonal influenza, traditional influenza vaccines may not be providing as much protection as we thought, leading researchers to take a look at different methods of vaccine production, specifically cell-based flu vaccine production. Here with Dr. Charles Turck to discuss influenza prevention and the latest evidence supporting a cell-based vaccine option is Dr. Mark Blatter.
USA-QIVc-21-0146 November 2021
Host: Paul P. Doghramji, MD, FAAFP
Guest: Mojgan Saber, MD
Can Locum Tenens be an option for healthcare professionals just completing their residency? Dr. Paul Doghramji is joined by Dr. Mojgan Saber to share her own experience as well as tips and tricks for residents looking at Locum Tenens right after residency.
Host: Charles P. Vega, MD
Guest: Sateria Venable
Regional healthcare disparities are biases that are based on where people live. Are your patients’ treatment options being impacted and limited by their geographical location? Join us as our two experts discuss how to support broader policy issues and highlight the importance of diagnostic algorithms that have been developed with diverse input. These steps may be of value in your clinical practice to ensure all patients have equal access to care regardless of their epidemiologic, socioeconomic, or insurance circumstances.
Host: Jennifer Shu, MD, FAAP
Tune in to hear pediatrician Dr. Jennifer Shu share what we currently know about the risks and impacts of the Delta variant on our youngest patients and perhaps even more importantly, how we can help keep them safe.
Published September 23, 2021
Host: Jennifer Shu, MD, FAAP
School’s back in session, and that means it’s time we take a look at how we can help keep children safe and healthy both inside and outside the classroom with pediatrician Dr. Jennifer Shu.
Published September 21, 2021
Host: Hector O. Chapa, MD, FACOG
Guest: Susan Crowe, MD
Both UNICEF and WHO recommend exclusive breastfeeding for the first six months of life, starting within the very first hour of birth. But are we adhering to that recommendation? Joining Dr. Hector Chapa to discuss the importance of breastfeeding shortly after delivery and how we can help our patients and their newborns reap the benefits of this golden hour is Dr. Susan Crowe, Director of Outpatient Breastfeeding Medicine Consultative Services at Stanford Children's Health who recently spoke about this topic at the 2021 ACOG Annual Clinical and Scientific Meeting.
Host: Cassandra B. Donnelly, DO
Guest: Charles P. Vega, MD
Post-exposure influenza prophylaxis should be a top-of-mind discussion with patients receiving an influenza diagnosis. Unfortunately, it remains an underused means to reduce secondary infections in at-risk households. Join Drs. Cassandra Donnelly and Charles Vega as they examine an extended patient case and offer practical strategies to overcome common clinical barriers surrounding post-exposure influenza prophylaxis, including how to match the right patient with the right antiviral treatment.
Host: Cassandra B. Donnelly, DO
Guest: Charles P. Vega, MD
Antiviral agents are underutilized against influenza in clinical practice, a failure that places many patients, especially those with comorbidities, at high risk for influenza-associated complications. Join Drs. Cassandra Donnelly and Charles Vega as they explore management strategies for patients with symptomatic influenza, compare and contrast clinical applications for the available antiviral agents, and reflect upon the increasing use of these agents as post-exposure influenza prophylaxis.
Guest: Kevan C. Herold, MD
Guest: Andrea Steck, MD
Guest: Anette Gabriele Ziegler, MD
Experts in the immunopathology of type 1 diabetes review data showing that clinical presentation is preceded by an asymptomatic phase, characterized by the presence of one or more islet autoantibodies. Screening children for islet autoantibodies during the two preclinical stages can identify those with multiple autoantibodies and high-risk antibody phenotypes who may be candidates for preventive interventions before developing dysglycemia or the clinical onset of type 1 diabetes.
Host: Eric Verdin, MD
Here to talk about some of the cellular changes associated with aging, how these changes manifest clinically as we age, and emerging nutritional interventions to target these changes is Dr. Eric Verdin, the President and Chief Executive Officer of the Buck Institute for Research on Aging.
Host: Peter Buch, MD, FACG, AGAF, FACP
Guest: Jeffrey Hyams, MD
Many studies focus on the impact of Crohn’s disease and ulcerative colitis in adult patients, but what about our youngest patients? To learn more about how we can treat our pediatric patients with Crohn’s disease and ulcerative colitis, Dr. Peter Buch speaks with Dr. Jeffrey Hyams, one of the world’s leading experts in pediatric inflammatory bowel disease.
Guest: Christie M. Ballantyne, MD
Host: John J. Russell, MD
According to the Consensus Statement published by the European Atherosclerosis Society, more than 90% (and maybe as high as 99%) of individuals with FH in the US have not been properly diagnosed due to gaps in screening, recognition and classification of FH. If not identified and aggressively treated from an early age, individuals with FH have a 20-fold increased life time risk of heart disease compared to the general population. However, with optimal treatment, an affected individual’s lifetime risk of cardiovascular disease approaches the risk found in the general population. Although the clinical symptoms are not as pronounced in cases of heterozygous FH, both homozygous (HoFH) and heterozygous FH (HeFH) patients still have an elevated risk of developing coronary heart disease at some point in their life. Early diagnosis and treatment for both HoFH and HeFH can significantly reduce the risk of coronary heart disease or delay its onset. Both homozygous and heterozygous FH are serious conditions that require special attention and treatment.
Guest: Kevan C. Herold, MD
Guest: Stephen Gitelman, MD
Experts in the immunopathology of type 1 diabetes consider the potential role of monoclonal antibodies, disease modifying agents, and other agents to prevent or delay the onset of clinical disease. Particular emphasis will be placed on the CD3 cell surface marker and anti-CD3 monoclonal antibodies, which has been shown to slow progression to clinical type 1 diabetes in high risk persons.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Nadia N. Laack, MD
As survival for patients with pediatric brain tumors improves, reducing the long-term effects of cancer treatment is increasingly important. Fortunately, proton radiotherapy along with several other advancements are helping us achieve that goal. Here to share the latest treatments for pediatric patients with brain tumors with Dr. Charles Turck is pediatric oncology physician Dr. Nadia Laack.
For more information about referring a patient to Mayo Clinic, please visit mayoclinic.org and for continuing medical education opportunities visit ce.mayo.edu.
Host: Peter Buch, MD, FACG, AGAF, FACP
Guest: Cynthia L Sears, M.D.
Decreased resistance to antibiotics has adversely impacted our ability to fight H. pylori. How can we help our patients overcome this threat? Dr. Peter Buch is here today to discuss this issue with Dr. Cynthia Sears, professor of medicine at the Johns Hopkins University School of Medicine to help improve health outcomes for our patients.
Host: Hector O. Chapa, MD, FACOG
Guest: Colin Quinn, MD
Guest: Matthew Wicklund, MD
Dr. Colin Quinn and Dr. Matthew Wicklund discuss the genetic and pathophysiologic underpinnings of limb girdle muscular dystrophy, as well as the use of appropriate diagnostic tests for accurate identification of LGMD.
Guest: Ramiz Kseri, MD
What do we need to keep in mind when treating adolescent transgender patients? Assistant Professor of Clinical Sciences at Florida State University College of Medicine, Dr. Ramiz Kseri, discusses bills impacting transgender rights, hormone blockers, and how we can provide better care for adolescent transgender patients.
Host: Jennifer Caudle, DO
Guest: Crystal Proud, MD
Guest: Edward Clinton Smith, MD
Dr. Crystal Proud and Dr. Edward Smith discuss the relationship of DMD genetics and pathophysiology and explain the importance of early diagnosis of Duchenne Muscular Dystrophy and the challenges associated with making this diagnosis.
Guest: Kevan C. Herold, MD
Guest: Chantal Mathieu, MD, PhD
Experts in the immunopathology of type 1 diabetes discuss the epidemiology, non-genetic and genetic risk factors, and progression from preclinical to clinical stages of this disease. The discussion will emphasize the breakdown of immune tolerance that precedes type 1 diabetes and the subsequent pathogenetic role of islet autoantibodies responsible for its clinical manifestations.
Host: Jennifer Shu, MD, FAAP
An important component of protecting our patients from the COVID-19 pandemic is taking care of their mental health. With that in mind, Dr. Jennifer Shu provides tips for keeping your young patients safe during the winter, and as they go back to school during the pandemic.
Host: Shannon L. Meeks, MD
Guest: Jonathan C. Roberts, MD
Dr. Shannon Meeks and Dr. Jonathan Roberts give an overview of the treatments used for the management of hemophilia A and discuss the safety and efficacy of these treatments. Using a patient case, they illustrate the pharmacovigilance process and explain how to implement this important reporting structure into everyday practice.
Host: Shannon L. Meeks, MD
Guest: Cindy Leissinger, MD
Pharmacovigilance begins after clinical trials end and new therapies enter everyday practice. Due to the rarity of hemophilia, participation in clinical trials has necessarily been small, and so monitoring the safety of new hemophilia treatments is especially important. Continued surveillance of adverse drug reactions (ADRs) after approval is a responsibility that falls on all members of the care team.
Dr. Shannon Meeks and Dr. Cindy Leissinger discuss the importance of safety surveillance and monitoring for novel hemophilia A therapeutics. To give a better understanding of pharmacovigilance, this activity includes animation that breaks down the process and illustrates where your ADR reports go and what happens next.
Host: Edward J. Mayeaux, Jr., MD, DABFP, FAAFP
Guest: Paul P. Doghramji, MD, FAAFP
Adherence to CDC vaccination recommendations is a public health issue and a topic of great concern for clinicians. According to the World Health Organization, vaccines ultimately reduce the burden of infectious disease and have the potential to save 2 to 3 million lives a year worldwide independent of their impact on morbidity. Join us as Drs. E.J. Mayeaux and Paul Doghramji discuss the challenges we’re all facing to overcome vaccine hesitancy and improve vaccine uptake, especially during the COVID-19 pandemic.
Host: Jennifer Caudle, DO
Guest: Anjali Patwardhan, MD
In pediatric patients, can the influenza and pneumococcal vaccines impact the COVID-19 disease course? Dr. Jennifer Caudle joins Dr. Anjali Patwardhan, a pediatric rheumatologist at the University of Missouri Healthcare, to discuss COVID-19 in pediatric patients who’ve been vaccinated for influenza and pneumococcal.
Published March 16, 2021
Host: Andrew Alexis, MD, MPH
Guest: Linda Stein Gold, MD
Depression, anxiety, failure to thrive, unemployment, low self-esteem, and suicidal ideation. What could possibly be contributing to all of these consequences? The culprit is acne—didn’t expect that, did you? Hear from dermatologists Dr. Andrew Alexis and Dr. Linda Stein Gold as they discuss the proper assessment of acne, its location—particularly beyond the face—and the differences to keep in mind when assessing skin of color. Faculty also examine the role that selective retinoid therapies play in treating acne and preventing the development of both the physical and psychological scars associated with this condition.
Host: Matthew J. Sorrentino, MD, FACC, FASH
Guest: Anita J. Moon-, MD, FAAP, FACC
Guest: Laxmi Ghimire, MD, FAAP
Dr. Matthew Sorrentino sits down with Dr. Anita Moon-Grady, a pediatric cardiologist at UCSFD, and Dr. Laxmi Ghimire, a pediatric specialist at Lake Region General Hospital to discuss the results from their recent study published in the American Journal of Cardiology, focusing on the prevalence of congenital heart disease in conjoined twins and higher-order multiple births.
Guest: Kevin Strauss, MD
Guest: Chamindra Konersman, MD
Affecting one in every 10,000 births worldwide, spinal muscular atrophy, also known as SMA, can result in the progressive loss of basic muscle function and in its most severe forms, can lead to death or the need for permanent ventilation in 90% of cases by age two. How can we help ensure that patients with this debilitating disease get diagnosed early, and what role does gene therapy play in its treatment? Tune in as Dr. Chamindra Konersman from Rady Children’s Hospital in San Diego discusses that and more with Dr. Kevin Strauss from the Clinic for Special Children in Pennsylvania.
© 2021 Novartis Gene Therapies, Inc. US-ZOL-20-0544 1/2021
Host: Jerome Lisk, MD
Guest: Anthony L. Fine, M.D
Recent advancements in the field of fetal neurology have equipped clinicians to detect neurological diseases before the child is even born. Dr. Jerome Lisk joins Dr. Anthony Fine, a pediatric neurologist and epileptologist at Mayo Clinic in Rochester, to discuss some of these advancements.
Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Michael D. Kappelman, MD, MPH
Pediatric care has evolved amid the COVID-19 pandemic. And when it comes to treating inflammatory bowel disorder, or IBD, gastroenterologists are faced with a unique set of challenges. Join us as Dr. Kappelman shares highlights of his presentation at the 2021 Crohn’s & Colitis Congress on what needs to be acknowledged while treating children with IBD during the COVID-19 pandemic.
Host: Kathy King, RDN
Guest: Megan Pesch, M.D.
Countless children across the nation are picky eaters, and families are on the lookout for effective solutions. With that in mind, Dr. Megan Pesch joins Kathy King to discuss her recent study on picky eaters and her insights on this common dilemma.
Host: Stacy Kahn, MD
Inflammatory bowel disease in pediatric patients is not as uncommon as you may think. Dr. Stacy Kahn, Assistant Professor of Pediatrics at Boston Children’s Hospital, shares her experience with healthy diet plans, preparing families for transition, and more.
Published August 7, 2020
Guest: Jennifer Shu, MD, FAAP
Tune in to hear Dr. Jennifer Shu describe what her life as a pediatrician is now like due to the COVID-19 pandemic and the steps she has taken to keep her patients and colleagues healthy.
Published June 12, 2020
Host: Joshua Sharfstein, MD
Guest: Elizabeth J. Letourneau, PhD
Responses to COVID-19 such as school closures and shelter-at-home orders may inadvertently raise the risks of child sexual abuse. Dr. Elizabeth Letourneau, Director of the Moore Center for the Prevention of Child Sexual Abuse, talks with Dr. Josh Sharfstein about risks, prevention strategies, and a new online resource for parents, caregivers, and people at risk of offending.
Published May 14, 2020
Host: Joshua Sharfstein, MD
Host: Sara Bennett, PhD
Guest: Timothy J. Roberton, DrPH
The global health community has worked for years to lower rates of maternal and child mortality in low- and middle-income countries. But while the world focuses on the number of deaths from COVID-19, estimates of indirect mortality due to disruptions in health systems cannot be ignored.
Tim Roberton, an assistant scientist in international health, talks with guest host Sara Bennett, a professor in international health, about a paper he co-authored that estimates there could be a 45 percent increase in child mortality and a 38 percent increase in maternal mortality in severe scenarios where care is disrupted due to COVID-19. One way to head off these numbers is to categorize care by prioritizing only emergency care that cannot be delivered in any other way.
Published May 7, 2020
Host: Joshua Sharfstein, MD
Guest: Matt Hornbeck
Schools are scrambling to figure out education during the COVID-19 pandemic. Matt Hornbeck, Principal of the top-rated Hampstead Hill Academy—a Pre-k-8 public school in southeast Baltimore city—says instruction is only part of the challenge: technology gaps, trying to reach vulnerable students, and the trauma of a sudden separation from friends and teachers are unprecedented issues to address. Hornbeck talks to Dr. Josh Sharfstein about how Hampstead Hill is trying to take care of its school community and how they’re preparing for the next period of uncertainty.
Published May 5, 2020
Host: Matt Birnholz, MD
Guest: Robbyn E. Sockolow, MD
Creating a seamless road map for pediatric patients with irritable bowel disease (IBD) transitioning to an adult gastroenterologist can be as simple as having educational discussions with the patient and their families. Dr. Robbyn Sockolow joins Dr. Matt Birnholz to share key topics to emphasize with your patients and how you can assist in their transition to an adult practice.
Host: Matt Birnholz, MD
Guest: Jeremy Adler, MD
To catch us up to spend on the unique care needs of our pediatric patients with IBD, Dr. Matt Birnholz spoke with Dr. Jeremy Adler, Head of the Pediatric IBD Program at the University of Michigan, at the third annual Crohn’s & Colitis Congress in Austin, Texas.
Host: Paul Doghramji, MD
Guest: Maria Escolar, MD, MS
Adrenoleukodystrophy (ALD) is a rare genetic disorder that when left untreated, can have severe and even fatal consequences. Here to review the available treatment options for these patients is Dr. Maria Escolar, the Director of the Program for the Study of Neurodevelopment in Rare Disorders and a Professor of Pediatrics at the University of Pittsburgh School of Medicine.
Host: Linda Bernstein, Pharm.D.
Allergic reactions to peanut are unpredictable in occurrence and in how they present, with some individuals experiencing severe reactions from even trace amounts. Fortunately, there’s now an FDA-approved treatment option available that—when used in conjunction with peanut avoidance—can help reduce the risk of these allergic reactions in children with peanut allergy, as pharmacist Dr. Linda Bernstein explains.
Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR
Please note: This activity is no longer available for continuing education credit.
Tune in as a multidisciplinary panel discusses a clinician's question about the appropriateness of combining two biologics in a very young child with several atopic diseases.
Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR
Please note: This activity is no longer available for continuing education credit.
Infants have the highest incidence of atopic dermatitis in the US but the fewest treatment options. This is a case a doctor submitted about a baby who is refractory to multiple oral and topical treatments. A multidisciplinary panel discusses how they would approach the baby's treatment, emerging options for this vulnerable patient population, and if anything can be done now to prevent progression of the atopic march later.
Host: Paul Doghramji, MD
Guest: Gregory S. Sawicki, MD, MPH
Even though there currently isn’t a cure for cystic fibrosis, there may finally be hope on the horizon for the more than 70,000 people around the world who are living with this debilitating disease. Joining Dr. Paul Dogramji to talk about the emerging treatment options for cystic fibrosis is Dr. Gregory Sawicki, Director at the Cystic Fibrosis Center and Assistant Professor of Pediatrics at Harvard Medical School.
Host: Paul Doghramji, MD
Guest: David H. Peyton, Ph.D.
The vaping epidemic is becoming more and more concerning, but could new research prompt people to quit? To find out, Dr. Paul Doghramji speaks with Dr. David Peyton about his recent study that challenges the claim that vaping devices take less of a toll on our health than tobacco smoking.
Host: Jennifer Caudle, DO
Guest: Barbara Pahud, MD
More patients are receiving conflicting information about vaccines, and after the rise of preventable outbreaks in 2019, Dr. Barbara Pahud joins Dr. Jennifer Caudle to debunk the most common myths surrounding vaccines and to share how we can better educate our patients.
Host: Jennifer Caudle, DO
To gain more insights into how inflammatory bowel disease (IBD) affects our young patients, Dr. Jennifer Caudle connects with Caroline, a 12-year-old patient who was diagnosed with IBD at the age of 4, and her parents, Preston and Rachelle, about the challenges they face and the strategies and solutions available that can help children and teens like Caroline manage this condition.
Guest: Jennifer Caudle, DO
It’s an unfortunate reality that an increasing number of patients are refusing to get vaccinated—regardless of whether that’s the recommendation for themselves or their children. But luckily, there are ways you can talk to your patients about this, as Dr. Jennifer Caudle explains.
Host: Alka Goyal, MD
Higher Postinduction Infliximab Serum Trough Levels Are Associated With Healing of Fistulizing Perianal Crohn’s Disease in Children.
Wael El-Matary, MD, MSc Thomas D Walters, MD Hien Q Huynh, MDJennifer deBruyn, MD David R Mack, MD Kevan Jacobson, MD Mary E Sherlock, MDPeter Church, MD Eytan Wine, MD, PhD Matthew W Carroll, MD, Eric I Benchimol, MD, PhD Sally Lawrence, MD Anne M Griffiths, MD
Background: There is some evidence in adults that higher serum infliximab (IFX) levels are needed to adequately treat fistulizing perianal Crohn's disease (CD). However, data in children are lacking. We aimed to determine postinduction serum trough IFX levels that are associated with healing of fistulizing perianal CD (PCD) at week 24.
Methods: In a multicenter inception cohort study, consecutive children younger than age 17 years with fistulizing perianal CD treated with IFX between April 2014 and June 2017 who had serum trough IFX titers measured before the fourth infusion were included. Area under the receiver operating characteristic curve (AUROC) was calculated to determine the best cutoff to predict fistula …
Host: Brian P. McDonough, MD, FAAFP
Guest: Teresa Gil, PhD
Since about 21 million mothers in America experienced sexual abuse in their childhood, there’s a good chance that some of these women are our patients. So as their physicians, how can we provide them with the best possible care as they continue to cope with the lifelong effects of sexual abuse? That’s what Dr. Brian McDonough explores with Dr. Teresa Gil, author of Women Who Were Sexually Abused as Children: Mothering, Resilience, and Protecting the Next Generation.
Host: Andrew Wilner, MD, FACP, FAAN
As physicians, we know that vaccines help protect people from preventable diseases, but somehow this message is getting lost among our patients. With more parents than ever choosing to skip the needle, Dr. Andrew Wilner dives into the 16th chapter of his book, Bullets and Brains, where he discusses the widespread benefits of vaccines and how they not only protect your patients’ children, but all of us.
Host: Athos Bousvaros, MD, MPH
Guest: Andrew B. Grossman, MD
Recorded at the second annual Crohn’s & Colitis Congress in Las Vegas, Dr. Athos Bousvaros and Dr. Andrew Grossman discuss IBD among pediatric patients and how optimizing various therapies is critically important to achieving disease remission.
Host: Andrew Wilner, MD, FACP, FAAN
Up until 2011, there was no FDA-approved antivenom for scorpion stings—until a very concerned pediatrician created one that came with seemingly miraculous results. Dr. Andrew Wilner breaks down this overlooked health threat and the development of its antivenom, which he explores in his book of essays called Bullets and Brains.
Host: Jennifer Caudle, DO
August is National Immunization Awareness Month sponsored by the National Public Health Information Coalition. Dr. Jennifer Caudle discusses the important role immunizations play in healthcare.
Host: Jennifer Caudle, DO
Guest: Sarah E. Domoff, PhD
To address the growing issue of prolonged screen time and media use among children, Dr. Jennifer Caudle speaks with Dr. Sarah Domoff, Director of the Family Health Lab at Central Michigan University, about the tools available to help physicians identify and curb screen addiction.
Host: Brian P. McDonough, MD, FAAFP
Guest: Tanya Altmann, MD
To investigate the concerning rise in both asthma and allergies in children, Dr. Brian McDonough is joined by Dr. Tanya Altmann, pediatrician and Editor in Chief of the American Academy of Pediatrics parenting books, to discuss why a missing component of the gut microbiome may be the potential cause and how nutrition and probiotics play a vital role in a child's growth and development.
Host: Jennifer Caudle, DO
Guest: Jean Bennett, MD, PhD
Guest: Albert Maguire, MD
Power couple Drs. Jean Bennett and Albert Maguire discuss how their new therapy for the RPE65 gene, which causes retinal blindness, was recently approved by the FDA to become the first gene therapy treatment for a genetic disease in the United States and the first worldwide treatment for inherited blindness. Not only do they delve into the mechanics of the corrected gene injection, but they also explain what this milestone means for patient eligibility and how their marriage has played a role in the success of their research partnership.
Dr. Jean Bennett is the F.M. Kirby Professor of Ophthalmology at the Perelman School of Medicine at the University of Pennsylvania, and Dr. Albert Maguire is a Professor of Ophthalmology at the Hospital of the University of Pennsylvania and Attending Physician in the Division of Pediatric Ophthalmology at Children’s Hospital of Philadelphia.
Host: Philip Stein, MD
Guest: Neilanjan Nandi, MD
Guest: Susan Peck, MSN, CRNP
From the ReachMD studios in Fort Washington, Pennsylvania, host Dr. Philip Stein talks with Dr. Neilanjan Nandi and nurse practitioner Susan Peck about their respective experiences with The Crohn’s & Colitis Foundation's Camp Oasis. This camp gives children with IBD the opportunity to meet other kids with the same chronic illness, teaching them how to cope with their disease, manage their own medical needs, try new sports and activities, build confidence and independence, and most importantly, spend quality time just being a kid.
Host: John J. Russell, MD
Guest: Thomas Doyle, MD
About 40,000 babies are born with Congenital Heart Disease each year, making it one of the most common birth defects and causes of infant death in the US. CHD is usually present at birth but shows very few outward signs and, in most cases has no known cause or origin.
New and evolving surgical techniques, along with the dawn of pediatric heart transplant, are transforming the field of pediatric cardiology and offer new options for CHD patients.
Host Dr. John Russell talks with Dr. Thomas Doyle about how continued research, improved surgical treatments and, emerging technology have altered the course of treatment for CHD, resulting in approximately 69% of children with CHD now living to age 18.
Dr. Thomas Doyle is the Ann and Monroe Carell Jr. Family Associate Professor of Pediatrics at Vanderbilt University. Dr. Doyle was a 2016 Project Heart CHD research grant recipient.
Host: Paul Rokuskie
Scientists have been doing research into many areas of autism spectrum disorder in the hopes of explaining the doubling of its prevalence rate over the past decade.
Both environmental risk factors and genetic components are areas of intense scrutiny for researchers seeking to understand the root causes of autism.
Host Paul Rokuskie talks with Craig Newschaffer, Professor, Associate Dean for Research, and Director of the A.J. Drexel Autism Institute, about the risk factors for autism spectrum disorder that scientists are working to better define.
Host: John J. Russell, MD
Do pets help prevent allergies? Does the 5-second rule actually exist? And is dirt really good for a child’s immune system?
Host Dr. John Russell talks with Jack Gilbert, Ph.D., Professor of Surgery at the University of Chicago and Director of the Microbiome Institute. Dr. Gilbert is author of the book Dirt is Good,answering questions about the potential benefits of exposure to germs and bacteria. He and Dr. Russell sift through common misconceptions about microbiomes to better understand their actual risks and benefits for the body's immune system, explaining its role in disease and health.
Host: Shira Johnson, MD
Guest: Robert Vonderheide, MD
For years, the foundations of cancer treatment, surgery, chemotherapy, and radiation therapy were utilized with the objective of weakening cancer.
But over the past several years, immunotherapy – therapies that enlist and strengthen the power of a patient’s immune system to attack tumors - has emerged as a new tool for fighting cancer. In August 2017, one such treatment approach, called Chimeric Antigen Receptor or CAR T-cell Therapy, received FDA approval for the treatment of children and young adults with acute lymphoblastic leukemia (ALL). Additionally, research is continuing to look at CAR-T therapy’s effectiveness for treating solid tumors as well.
Host Dr. Shira Johnson sits down with Dr. Robert Vonderheide, Director of the Abramson Cancer Center of the University of Pennsylvania and the John H. Glick, MD, Abramson Cancer Center Director’s Professor, to talk about the potential of CAR-T therapy alongside other emerging immunotherapies in fighting cancer.
Host: Paul Rokuskie
Over the past two decades, the world has seen a dramatic rise of individuals being diagnosed with autism spectrum disorder. For decades scientists and medical professionals have been researching various aspects of this disease to uncover genetic and environmental factors explaining this rapid increase in prevalence; however, discovering definitive clues to causality has proven elusive.
Host Paul Rokuskie talks with Dr. Craig Newschaffer, Professor, Associate Dean for Research, and Director of the A.J. Drexel Autism Institute about the latest research findings into environmental factors affecting autism risk.
Host: Paul Rokuskie
Researchers have been challenged for years by the simultaneous results of numerous studies into brain network connections in individuals with Autism Spectrum Disorder. Some results show strong connections, while others suggest the opposite. New research has helped bring some clarity to this ongoing paradox.
Host Paul Rokuskie is joined by Dr. Benjamin Yerys, a child psychologist in the Center for Autism Research (CAR) at the Children’s Hospital of Philadelphia. They talk about how it’s possible to see conflicting results and, paradoxically, for both to be true.
Host: Paul Rokuskie
Autism Spectrum Disorder affects communication skills as well as emotional & social development. Researchers have been studying the brain for decades to better understand how these developmental differences manifest as autism. Recent studies that measure rapid eye movement (REM) have been showing great promise in elucidating the origins and mechanisms of disease.
Host Paul Rokusie sits down with Dr. John Foxe to talk about his study on rapid eye movement, its implications on disease pathogenesis, and new insights it can bring to future autism research.
Anti-TNFα Treatment After Surgical Resection for Crohn's Disease Is Effective Despite Previous Pharmacodynamic Failure
Assa A1, Bronsky J, Kolho KL, Zarubova K, de Meij T, Ledder O, Sladek M, van Biervliet S, Strisciuglio C, Shamir R.
BACKGROUND: The outcome of patients with Crohn's disease who failed anti-tumor necrosis factor alpha (anti-TNFα) therapy despite adequate serum drug levels (pharmacodynamic failure) is unclear. We aimed to assess such pediatric patients who underwent intestinal resection and were re-treated with the same anti-TNFα agent postoperatively.
METHODS: Pediatric patients with Crohn's disease who underwent intestinal resection and were treated with anti-TNFα agents postoperatively were assessed retrospectively. Patients were stratified to those with preoperative anti-TNFα pharmacodynamic failure and those with no preoperative anti-TNFα treatment.
RESULTS: A total of 53 children were included, 18 with pharmacodynamic failure and 35 controls. Median age at intestinal resection was 14.8 years with 23 (43%) girls. The median time from intestinal resection to anti-TNFα initiation was 8 months (interquartile range 4-14 months). At the time of postoperative anti-TNFα initiation, there were no differences in clinical, laboratory, and anthropometric measures between groups. Similar proportions of patients from both groups were in clinical remission on anti-TNFα treatment after 12 months and at the …
Host: Brian P. McDonough, MD, FAAFP
Could constant cell phone use be damaging children's brains?
Host Dr. Brian McDonough chats with Daniel Debaun, author of Radiation Nation: The Fallout of Modern Technology," about how electromagnetic frequency (EMF) radiation produced by modern technology such as cell phones, tablets, laptops, Wi-Fi, and smart meters may be emerging as a health threat with many unknown consequences.
Host: Adam Ehrlich, MD, MPH
Guest: Philip Stein, MD
The majority of adolescents with inflammatory bowel disease (IBD) will transition from a pediatric to an adult specialist. This process can be daunting, especially if patients are not ready to take control of their health care. However, with the right communication and preparation, the transition can be smooth for the patient, parent, and physician. Host Dr. Adam Ehrlich joins Dr. Philip Stein, a pediatric gastroenterologist at St. Christopher’s Hospital for Children, to discuss how physicians can best prepare patients to transition and overcome potential difficulties.
Host: Brian P. McDonough, MD, FAAFP
Guest: Howard Spiva
Wearing a helmet is an overlooked but critical safety precaution, particularly among children. Attorney Howard Spiva knows the lifelong struggle of individuals recovering from traumatic brain injuries, having devoting much of his career to providing helmet safety education for children. Joined by host Brian McDonough, Mr. Spiva discusses important details about helmet safety, the current status of helmet laws, and continuing efforts to reduce traumatic brain injuries nationwide.
Host: Maurice Pickard, MD
Guest: Elijah Nealy, PhD
These days, it is practically impossible not to hear about some aspect of transgender life, and kids are coming out as trans at younger and younger ages. But what resources are available to parents, teachers, and mental health professionals who need to support these children?
Host Dr. Maurice Pickard chats with Elijah C. Nealy, therapist and former deputy executive director of New York City’s LGBT Community Center. Mr. Nealy is the author of Transgender Children and Youth: Cultivating Pride and Joy with Families in Transition, which provides insights about the physical, social, and emotional aspects of transition and the best practices to support trans kids.
Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy.
Sands BE1, Sandborn WJ, Van Assche G, Lukas M, Xu J, James A, Abhyankar B, Lasch K.
BACKGROUND: Vedolizumab is a gut-selective α4β7 integrin antagonist for the treatment of moderately to severely active Crohn's disease (CD). Aims of this study were to characterize the efficacy and safety of vedolizumab induction and maintenance therapy in patients who were naïve to tumor necrosis factor-alpha (TNF-α) antagonist therapy (TNF-naïve) or who had discontinued TNF-α antagonist therapy because of inadequate response (i.e., primary nonresponse), loss of response, or intolerance (collectively classified as the TNF-failure population).
METHODS: Post hoc analyses of the efficacy data for 516 TNF-naïve and 960 TNF-failure patients from the GEMINI 2 and GEMINI 3 trials were evaluated at weeks 6, 10, and 52 and included clinical remission (CD Activity Index [CDAI] score ≤150), enhanced clinical response (≥100-point decrease from baseline in CDAI score), durable clinical remission (remission at ≥80% of visits), and corticosteroid-free remission. Adverse events were summarized for the TNF-naïve and TNF-failure subgroups by treatment received.
RESULTS: Among patients who responded to vedolizumab induction at week 6, 48.9% …
The Food and Drug Administration (FDA) is restricting the use of codeine and tramadol medicines in children. Codeine is approved to treat pain and cough, and tramadol is approved to treat pain. These medicines carry serious risks, including slowed or difficult breathing and death, which appear to be a greater risk in children younger than 12 years, and should not be used in these children. These medicines should also be limited in some older children. Single-ingredient codeine and all tramadol-containing products are FDA-approved only for use in adults. The FDA is also recommending against the use of codeine and tramadol medicines in breastfeeding mothers due to possible harm to their infants.
As a result, the FDA is requiring several changes to the labels of all prescription medicines containing these drugs. These new actions further limit the use of these medicines beyond the 2013 restriction of codeine use in children younger than 18 years to treat pain after surgery to remove the tonsils and/or adenoids. The FDA is now adding:
- FDA’s strongest warning, called a Contraindication, to the drug labels of codeine and tramadol alerting that codeine should not be used to treat pain or cough and tramadol …
Host: Prathima Setty, MD
A couple of extra minutes attached to the umbilical cord at birth may translate into a significant boost in neurodevelopment several years later, research suggests.
Dr. Prathima Setty is joined by Dr. Kecia Gaither, a perinatal consultant at St. Lukes Hospital in Kansas City, MO as they talk about how delaying cutting the umbilical cord can be beneficial.
Host: Jennifer Caudle, DO
Sleep apnea in children can lead to many behavioral, school and social problems. Recent research has even suggested that children who snore loudly were found to be twice as likely to have learning problems as children who don’t snore. What can be done to minimize sleep apnea in children?
On this episode of Everyday Family Medicine, Dr. Jennifer Caudle speaks with Dr. Diana Batoon, dentist and founder of Bonita Dental in Scottsdale, Arizona. Dr. Batoon has devoted much of her dental practice and public education efforts around identifying and treating sleep apnea in children.
Host: David Weisman, MD
Dr. David Weisman explores a study from Wake Forest School of Medicine that examined the effects of concussions for youth football participants.
Host: Paul Rokuskie
As medical professionals gain better understandings of the etiologies, mechanisms, and progressions of autism spectrum disorder, they are looking for ways to standardize this diagnosis. This creates new needs to change the way autism is conceptualized clinically, from severity scales to behavioral impacts on quality of life.
Host Paul Rokuskie welcomes Dr. Sven Bolte, Professor of Child and Adolescent Psychiatric Science and Director of the Center of Neurodevelopmental Disorders at Karolinska Institute in Stockholm, Sweden. The two discuss the complex process for building new diagnostic criteria for autism spectrum disorder.
Host: Brian P. McDonough, MD, FAAFP
Holidays, life events, and even seasonal changes in general can cause an extraordinary amount of stress for young children.
Host Dr. Brian McDonough chats with Christine Bronstein, entrepreneur and author of the children’s series Stewie Boom!, about different methods gleaned from pediatricians and other parents to help children cope with stress.
Host: Ana Maria Rosario
Guest: Martin R. Chavez, MD, FACOG
From the Women's Health Annual Visit in Chicago, host Ana Maria Rosario talks with Dr. Martin Chavez, the Director of Maternal Fetal Medicine and Fetal Surgery Program at Winthrop University Hospital, about the maternal-fetal effects of the Zika virus outbreak.
Host: Jennifer Caudle, DO
Parents today are bombarded with confusing and sometimes harmful information in regard to which foods are best to give their kids. Nutritional guidelines are constantly changing and parents don’t know who to trust for medically sound and proven advice that works.
Host Dr. Jennifer Caudle sits down with Dr. Tanya Altmann, pediatrician, founder of Calabasas Pediatrics, and author of the book, What to Feed Your Baby: A Pediatrician’s Guide to the 11 Essential Foods to Guarantee Veggie-Loving, No Fuss, Healthy Eating Kids. The two talk about the importance of introducing children to healthy eating habits from an early age to ensure a good eating adult lifestyle.
Host: Patrice L Basanta-Henry, MD, MHSc, FACOG
Approximately just 0.5% of all births occur before the third trimester of pregnancy, yet these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. Care for infants born at the threshold of viability, less than 24 weeks of gestation and with body weights less than 1000 grams, poses many difficult clinical, social, and ethical questions among clinicians and families.
Host Dr. Patrice Basanta-Henry speaks with guest Dr. Fyama Wenner, a maternal-fetal medicine specialist at Atlanta Maternal Fetal Medicine, about special care considerations for extremely preterm infants, as well as effective counseling strategies for families.
Microbial colonization and lung function in adolescents with cystic fibrosis. Hector A, Kirn T, Ralhan A, Graepler-Mainka U, Berenbrinker S, Riethmueller J, Hogardt M, Wagner M, Pfleger A, Autenrieth I, Kappler M, Griese M, Eber E, Martus P, Hartl D. J Cyst Fibros. 2016 May;15(3):340-9. doi: 10.1016/j.jcf.2016.01.004. Epub 2016 Feb 5.
Abstract With intensified antibiotic therapy and longer survival, patients with cystic fibrosis (CF) are colonized with a more complex pattern ofbacteria and fungi. However, the clinical relevance of these emerging pathogens for lung function remains poorly defined. The aim ofthis study was to assess the association of bacterial and fungal colonization patterns with lung function in adolescent patients with CF. Microbial colonization patterns and lung function parameters were assessed in 770 adolescent European (German/Austrian) CF patients in a retrospective study (median follow-up time: 10years). Colonization with Pseudomonas aeruginosa and MRSA were most strongly associated with loss of lung function, while mainly colonization with Haemophilus influenzae was associated with preservedlung function. Aspergillus fumigatus was the only species that was associated with an increased risk for infection with P. aeruginosa.Microbial interaction analysis revealed three distinct microbial clusters within the longitudinal course of CF lung disease. …
[Read the Article]
Since the legalization of marijuana in Colorado, there has been an increase in hospital visits and calls to regional poison centers due to unintentional marijuana exposure among young children. Researchers from the University of Colorado evaluated the number of children with exposures before and after recreational marijuana was legalized.
Between 2009 and 2015 they found a rise in the annual number of unintentional pediatric exposures. On average, these children were about two years old. Most children ingested the drug in edible forms such as candies and baked goods. Almost half of the patients seen in the children's hospital in the 2 years after legalization had exposures from recreational marijuana, suggesting that legalization did affect the incidence of exposures.
[Watch more videos of The JAMA Report]
[Read the Article]
A new study suggests that teens undergoing bariatric surgery can experience benefits in terms of walking speed and joint pain. Researchers from the University of Minnesota School of Medicine are tracking long-term outcomes for 242 teens that underwent bariatric surgery at five centers around the United States.
For the current study, researchers specifically focused on improvements in mobility and pain related to muscles and joints is a subset of 206 patients. All patients participated in a quarter mile walk test before and after surgery at six months, twelve months and twenty-four months. Improvements in time to complete the walk, resting heart rate and heart rate differences continued at one and two years after surgery.
[Watch more videos of The JAMA Report]
Host: Jennifer Caudle, DO
Pectus excavatum is an uncommon condition, but a highly impactful one for those who are born with it. What do physicians need to know about pectus excavatum when encountering it in practice, and what new advances in treatment are on the horizon?
Host Dr. Jennifer Caudle sits down with Dr. Dawn Jaroszewski, a cardiovascular surgeon at the Mayo Clinic, to talk about research updates and treatment options for patients with pectus excavatum.
Host: Brian P. McDonough, MD, FAAFP
Joe Klest, Chicago attorney and author of The Whole Truth. Mr. Klest has represented victims in over 500 sexual abuse cases. He and Dr. McDonough discuss clinical recognition methods and action plans for child abuse, legal contexts for reporting, and the need for increased awareness by clinicians in primary care settings.
Host: Brian P. McDonough, MD, FAAFP
Dr. Brian McDonough welcomes Denise Daniels, Peabody Award-wining broadcast journalist, author, and child development expert who specializes in the social and emotional development of children. Ms. Daniels talks about the challenges in helping children cope with the consistent exposure to tragic news around the world stemming from terrorism, wars, and natural disasters.
Host: Renée Simone Yolanda Allen, MD, MHSc., FACOG
Babies born before 37 weeks gestation face many challenges in their first weeks of life. For premature babies to thrive in the NICU, the American Academy of Pediatrics recommends all preterm babies weighing less than 1500 grams be fed human milk. However, this recommendation creates a dilemma for mothers who are unable to supply their own breast milk and must therefore turn to donation programs to feed their babies.
Dr. Renee Allen chats with Scott Elster, CEO of Prolacta Bioscience, about the goals of breast milk donor programs to improve health outcomes for critically ill preemies, while also reducing NICU costs.
Host: Paul Rokuskie
Recent studies have uncovered sex differences in both the neurobiology and phenotypical presentations of autism. These emerging understandings for how autism manifests uniquely in girls vs boys may radically change the way autism spectrum disorder is clinically perceived, improving diagnostic sensitivity and personalizing therapies.
Joining host Paul Rokuskie to discuss this line of research developments in autism spectrum disorder is Dr. Kaustubh Supekar, research scientist in the Department of Psychiatry at Stanford University School of Medicine.
[Read the Article]
Air pollution is associated with chronic respiratory health problems in children. A new study examined whether decreases in air pollution levels are associated with significant reductions in respiratory symptoms in children.
Researchers from the University of Southern California followed over 4,600 children in eight Southern California communities across three different time periods from 1993-2012. In addition to monitoring air quality, they also looked at children with and without asthma, and whether they reported respiratory symptoms like bronchitis, congestion, phlegm production, or a daily cough for three months in a row, during the previous year.
Along with significant improvements in air pollution levels, the authors found a decrease in reported respiratory symptoms in children both with and without asthma. Respiratory symptoms decreased by 32 percent in children with asthma and 21 percent in children without.
[Watch more videos of The JAMA Report]
[Read the Article]
Recent outbreaks of vaccine-preventable diseases in the United States have prompted clinicians, public health officials and the public to pay closer attention to the growing phenomenon of vaccine refusal. A new study looks at the role of vaccine refusal and the risk of measles and pertussis. In recent years, a substantial proportion of US measles cases occurred in people who were intentionally unvaccinated. Vaccine refusal was also found to be associated with an increased risk of pertussis in some populations.
[Watch more videos of The JAMA Report]
Host: Paul Rokuskie
Host Paul Rokuski welcomes Dr. Sally Rogers, Professor of Psychiatry & Behavioral Sciences and Director of Training and Mentoring at the MIND Institute of the University of California-Davis. Dr. Rogers specializes in conducting developmental and treatment research into autism and other developmental disorders. She is currently focused on developing and improving treatments for early autism using a treatment model that she developed in collaboration with Geraldine Dawson, the Early Start Denver Model.
[Read the Article]
Approximately one-third of children who experience a concussion will experience persistent post-concussion symptoms. Researchers have developed a new clinical scoring system that may help predict which patients are at a higher risk for prolonged symptoms.
Canadian researchers evaluated more than 3,000 patients, ages 5 to 18, who presented within 48 hours of an acute head injury. About thirty percent ended up with persistent post-concussion symptoms at 28 days. Researchers identified nine clinical factors that were predictive of post-concussive symptoms. These factors were then used in a twelve point risk score that included items like age, sex, history of migraines or depression, prior history of concussion, and problems with balance.
Although the clinical score was better than a physician's judgement alone, further research is needed before it is fully adopted into clinical practice.
[Watch more videos of The JAMA Report]
Host: Brian P. McDonough, MD, FAAFP
Kidney stones are on the rise, particularly among adolescents, females, and African-Americans in the U.S. This marks a striking change from the historic pattern in which middle-aged white men were at highest risk for the painful condition. While the overall increase in kidney stones in children and adolescents has been known, a recent study published in the Clinical Journal of the American Society of Nephrology provided greater clarity on the specific groups of patients at greatest risk by analyzing age, race and sex characteristics among children and adults in South Carolina over a 16-year period, from 1997 to 2012.
Lead author Dr. Gregory Tasian, Assistant Professor of Urology at the University of Pennsylvania Perelman School of Medicine and an attending pediatric urologist at The Children's Hospital of Philadelphia, joins Dr. Brian McDonough to discuss this startling trend, the factors that may be driving it, and appropriate preventive and treatment strategies for kidney stones.
Host: Alicia A. Sutton
From the floors of Omnia Education's Women's Health Annual Visit in Washington DC, host Alicia Sutton interviews Dr. Joel Weinthal, Clinical Associate Professor of Pediatrics at Texas Tech University Health Sciences Center and Medical Director of the Stem Cell Transplant Laboratory at Medical City Dallas Hospital. The two discuss Dr. Weinthal's current work in regenerative medicine, the scope of clinical utilization and potential, ethical considerations, and anticipated directions for the field.
[Read the Article]
Preschool children who experience repeated episodes of severe lower respiratory tract infections (LRTI) often present with symptoms like wheezing and difficulty breathing. A new study looked at whether the use of the common antibiotic, azithromycin, would help prevent progression of the illness, if given early enough in the episode.
Researchers from Washington University in Saint Louis School of Medicine, studied more than 600 children, ranging from ages one to six years old, with a history of repeated episodes of severe respiratory illness. Children were randomly assigned to either receive azithromycin or a placebo early in these episodes.
They found that children in the antibiotic group experienced a lower risk of progressing to severe LRTI than the placebo group.
[Watch more videos of The JAMA Report]
Host: Brian P. McDonough, MD, FAAFP
Joining Dr. Brian McDonough to discuss updated considerations and approaches to the pre-participation physical exam is Dr. Mark Mirabelli, Assistant Professor in the Departments of Orthopedics, Family Medicine, and Physiatry at the University of Rochester Medical Center in Rochester, NY. Dr. Mirabelli is a medical consultant to regional professional and college sports teams. He also serves as the supervising physician for University Sports Medicine athletic trainers at several area high schools. Their discussion centers on the most vital health concerns for young athletes, from cardiac screening protocols to asthma maintenance to concussion assessments.
Host: Jennifer Caudle, DO
Dr. Jennifer Caudle welcomes Dr. Patrick Spencer, Chairman of the Department of Ophthalmology at Grandview Medical Center in Dayton, Ohio. Their discussion centers on primary care manifestations of sickle cell retinopathy, from early to late-stage presentations and the gold standard treatment approaches along this disease course.
[Read the Article]
In the United States, seasonal influenza epidemics are responsible for an estimated 226,000 hospitalizations and between 3,000 and 49,000 deaths each year. Pneumonia, the leading infectious cause of hospitalization and death in the United States, is a serious complication of influenza. A new study examined whether getting a flu shot can help reduce hospitalizations due to influenza pneumonia.
Researchers from Vanderbilt University Medical Center evaluated more than 2,700 patients from January 2010 to June 2012. All patients had pneumonia and were admitted to the hospital from the emergency department. Overall, about six percent of patients had pneumonia due to influenza.
Researchers estimated that the patients who received influenza vaccine had a 57 percent less chance of getting hospitalized with influenza-pneumonia than those patients who were not vaccinated.
[Watch more videos of The JAMA Report]
JAMA Report videos provided pursuant to license. ©2015 American Medical Association, publisher of JAMA® and The JAMA Network® journals.
Host: Prathima Setty, MD
Disorders of sex development (DSDs) occur more frequently than most people realize, and yet there are numerous misconceptions persisting in the clinical arena as to how these disorders are best approached. For example, whereas older prevailing sentiments on presentations of ambiguous genitalia called for immediate sex assignments at birth followed by surgical alignments of those decisions, more modern philosophies advocate for direct patient involvement in these decisions a little later in life.
Joining Dr. Prathima Setty to focus on this important topic is Dr. Earl Cheng, Professor of Urology, Division Head of Urology and Co-Head of Reconstructive Pediatric Urology at Northwestern University Feinberg School of Medicine. Dr. Cheng directs the Gender and Sex Development Program at Ann & Robert H. Lurie Children's Hospital of Chicago.
[Read the Article]
Electronic cigarettes (e-cigarettes) are becoming increasingly popular among teens. A new study looks at whether younger teens who never smoked cigarettes and who begin using e-cigarettes might be more likely to go on to use conventional tobacco products.
Researchers from the University of Southern California, Los Angeles surveyed more than 2,300 Los Angeles area high school students who reported never using tobacco products at the beginning of 9th grade. The students were surveyed again six months later and also when entering the 10th grade.
In a comparison of teens who had used e-cigarettes to those who had not, the researchers found that those who had used e-cigarettes were four times more likely to have gone on to use conventional tobacco products, including cigarettes and cigars. The researchers acknowledge that their findings, while suggestive, cannot prove that e-cigarette use directly causes subsequent tobacco use.
[Watch more videos of The JAMA Report]
JAMA Report videos provided pursuant to license. ©2015 American Medical Association, publisher of JAMA® and The JAMA Network® journals.
Host: Paul Rokuskie
Autism Spectrum Disorder has had some profound effects on our global culture over the past few years. As greater understandings of this neurological disorder are communicated by scientists, physicians, advocacy groups, educational professionals and parents, public awareness shifts and societies reshape how autism is ultimately perceived.
Paul Rokuskie welcomes Richard Grinker, PhD, Professor and Chair of Anthropology, and Director of the Institute for Ethnographic Research, at the George Washington University. Their discussion centers on how cultures are affecting the way autism is understood, evaluated, and even diagnosed across the world.
Irritable bowel syndrome is becoming increasingly recognized as a complex interplay of pathologies, from changes in gut microflora to nutrient absorption abnormalities to psychosocial stressors. The ways in which these factors contribute and interact create different profiles of disease, requiring personalized therapeutic plans for IBS patiets. Joining Dr. Barry Mennen to discuss a multimodal model for approaching the root causes of IBS is Dr. Neelesh A. Tipnis, the Paul H. Parker Professor and Chair of Pediatric Gastroenterology and Director of the GI Motility and Functional Bowel Disorders Program at the University of Mississippi Medical Center.
Host: Paul Rokuskie
Social and emotional skills come fairly easily for neurotypical individuals. But for those with a diagnosis of Autism Spectrum Disorder (ASD), these may be some of the most challenging skills to learn. Thankfully there is a lot of experience among educators using techniques to help individuals with ASD become more social. Join host Paul Rokuskie as he welcomes speech/language pathologist Jill Kuzma to discuss therapeutic approaches for social cognitive deficits in children with ASD.
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
Host Dr. Alan Brown welcomes Dr. Don Wilson, Endocrinologist at Cook Children's Health Care System, Fort Worth, Texas. Dr. Wilson will review dyslipidemia in children and adolescent patients. Key points of their discussion will cover the association between abnormal lipid levels in children and an increased lifetime risk of atherosclerotic CVD, as well as, the CVD risk factors present in children and how it tracks from childhood to adulthood.
Supported by an Educational Grant from AstraZeneca.
Supported by an Educational Grant from AstraZeneca. - See more at: https://reachmd.com/programs/lipid-luminations/million-hearts-initiative-dr-janet-wright-executive-director/7439/#sthash.aVHL9OOn.dpuf Supported by an Educational Grant from AstraZeneca. - See more at: https://reachmd.com/programs/lipid-luminations/million-hearts-initiative-dr-janet-wright-executive-director/7439/#sthash.aVHL9OOn.dpuf
Over the past decade, Food Protein Enterocolitis, or FPIES, has emerged as the most actively studied non–IgE-mediated gastrointestinal food allergy because of its acute onset, severity of symptoms, and distinctive clinical features. Yet as a rare allergic disorder of infancy and young childhood, it is often misinterpreted and misdiagnosed in clinical practice, leading to difficult treatment paths for patients and their families. Joining Dr. Renee Matthews to present a case history from the vantage point of a patient's mother, including challenges faced in reaching the correct diagnosis and starting effective treatment regimens, is Jennifer Kandt.
Host: Paul Rokuskie
Autism spectrum disorder has been around for centuries, but the modern terminology of how it is defined only started in 1943 by Dr. Leo Kanner of Johns Hopkins Hospital. Since then, the definition of autism has changed many times, refined into today’s current understanding of this mental disorder. But one point of constancy over this time frame has been the advocacy work of mothers and fathers to better understand the disease that impacts their children’s lives, helping educate communities around them in turn to foster greater compassion and awareness.
In this episode of the Autism Spectrum, host Paul Rokuskie speaks with Eustacia Cutler, autism rights advocate and mother of Dr. Temple Grandin, who is often referred to as the first person officially diagnosed with autism in the United States.
Host: John J. Russell, MD
Internationally respected neurologist Frances E. Jensen, M.D. speaks with host John Russell, MD about her book, The Teenage Brain: A Neuroscientist's Survival Guide To Raising Adolescents And Young Adults. This insightful book offers new findings and dispells myths and also provides practical advice for parents and teenagers.
This week, hosts Mark Masselli and Margaret Flinter speak with Dr. John Lumpkin, Sr. VP and Director of Targeted Teams at the Robert Wood Johnson Foundation. Dr. Lumpkin runs the RWJF project targeting childhood obesity and talks about the myriad strategies aimed reducing the obesity epidemic among the nation's children.
Host: Brian P. McDonough, MD, FAAFP
Nearly 55% of infants in the United States sleep on unsafe bedding, despite warnings from the Centers for Disease Control and the American Academy of Sleep Medicine to use firm flat surfaces covered with fitted sheets. Parents are being presented with several more comfortable, "baby friendly" appearing alternatives, as well as having their infants children sleep with them in their own beds, both of which create risks of SIDS and roll-over suffocations, respectively. Joining Dr. Brian McDonough to discuss safety standards and health priorities for infant sleep habits is Dr. Shalini Paruthi, Assistant Professor in the Divisions of Pulmonary Medicine and Sleep Medicine, and Director of the Pediatric Sleep Research Center at St. Louis University School of Medicine.
Host: Brian P. McDonough, MD, FAAFP
The controversy over vaccinations and whether or not to regulate their administration has reached a boiling point in the United States with the recent measles outbreak originating in Disneyland, and prominent politicians like Senator Rand Paul and Governor Chris Christie have weighed in to support the anti-vaccine community's appeal for individual choice. What are the ethical, sociological, and political ramifications of these developments in the national vaccination debate, and how should the medical community respond? Joining Dr. Brian McDonough to discuss the vaccination controversy is Dr. Arthur Caplan, Professor and founding Director of the Division of Medical Ethics in NYU Langone Medical Center’s Department of Population Health.
Host: Paul Rokuskie
Associations between autism and gastrointestinal health are being actively investigated in medical research. Two major projects, each spanning three years, are focusing in particular on intestinal bacteria, ie the microbiome, and constipation, respectively. Leading the charge on these investigations are Drs. Pat Levitt and James Versalovic. Dr. Levitt is Chair of Developmental Neurogenetics at Children's Hospital - Los Angeles (CHLA), while Dr. Versalovic is Chief of the Department of Pathology at Texas Children's Hospital. Their work seeks to better understand how the human microbiome impacts neural health and development, and how refined treatments aimed at changing this potential "gut/brain axis" may aid therapies for autism and other neurodevelopmental disorders.
The funding for the research project that Dr. Pat Levitt and Dr. James Versalovic are conducting is awarded by a grant from Autism Speaks.
Host: Brian P. McDonough, MD, FAAFP
The notorious "Freshman 15" equates to weight gain commonly experienced by college-age students living away from home for the first time. How does this problem in weight management and healthy nutrition surface in primary care practice, and how can college students be counseled to avoid gaining extra weight during their first year? Joining Dr. Brian McDonough to speak on this subject is Alice Holland, RNP, Director of Student Health Services at Quinnipiac University in Hamden, Connecticut.
This week, Mark and Margaret speak with Carolyn Miles, President & Chief Executive Officer of Save the Children. Save the Children is the leading independent organization inspiring breakthroughs in how the world treats children, achieving immediate and lasting change in their lives. The global Save the Children movement currently serves over 143 million children in the US and in 120 countries. During her senior leadership tenure, the organization has more than doubled the number of children it reaches with nutrition, health, education and other programs. Resources have gone from $250m to almost $700m, with 89.4% spent on programs for children. Carolyn has focused on hunger, learning outcomes, and ending preventable child deaths as her signature issues.
The Gender, Sexuality and HIV Prevention Center at Ann & Robert H Lurie Children's Hospital of Chicago is the first of its kind facilty for adolescent patients. Host Dr. Jennifer Caudle welcoms the center's director, Dr. Robert Garofalo. Dr. Garofalo will share the center's mission of supporting multidisciplinary academic subjects including sexual health, gender, sexuality, HIV prevention and health disparities which affect adolescent and young adult populations at risk of acquiring HIV. The Center partners with similar organizations throughout the country in creating an environment where clinicians, academics and scientists can collaborate to design projects with public health significance.
Robert Garofalo, MD, MPH, is Professor of Pediatrics and Preventive Medicine at Northwestern University Feinberg School of Medicine. He is also an Attending Physician at Lurie Children's, where he directs the Adolescent/Young Adult HIV Program. Dr. Garofalo is a national authority on LGBT health issues, adolescent sexuality, and HIV clinical care and prevention.
Host: Brian P. McDonough, MD, FAAFP
Dr. McDonough addresses the lack of conversation about sex with teen patients according to a new study from American Medical Association, Pediatrics, and Duke University researchers,
Host: Tim Rush
Host Tim Rush welcomes Dr. Ali Kavianian, who after retiring, decided to go back to practicing medicine. Dr. Kavianian founded a group called Pediatric Surgical Associates and later became Surgeon-in-Chief at a pediatric hospital in Southern California. He is now able to enjoy the benefits of retirement and work locum tenens assignments.
Download and listen today!
Host: Brian P. McDonough, MD, FAAFP
Dr. Brian McDonough welcomes Dr. Nancy Fan, practicing OB/GYN at Saint Francis Hospital in Wilmington, DE and current Chair of the School Health Committee for the Medical Society of Delaware, to discuss challenges and controversies surrounding breast feeding recommendations in maternity care practice.
Host: Paul Rokuskie
Autism Spectrum Disorder (ASD) is a significant public health issue, affecting over 1% of all American children under the age of 18. One organization, Autism Speaks, is accelerating the care of these individuals and their families to the next level through their Autism Treatment Network, which creates collaborations that bridge multiple discplines across the United States. Joining host Paul Rokuskie to elaborate on this initiative is Dr. Dan Coury, Professor of Pediatrics and Psychiatry at Ohio State University and Medical Director of the Autism Treatment Network.
Host: Paul Rokuskie
For some time, serotonin and vitamin D have been proposed to play a role in autism, but until recently no causal mechanism has ever been established. Autism researchers Dr. Bruce Ames and Dr. Rhonda Patrick of Children's Hospital Oakland Research Institute (CHORI) join host Paul Rokuskie to discuss their study on the demonstrated impact of Vitamin D on social behavior associated with Autism Spectrum Disorder (ASD). Their research implicates vitamin D as an activator of serotonin, oxytocin, and vasopressin, three brain hormones that affect social behavior related to autism.
Host: Prathima Setty, MD
According to the American Heart Association, childhood obesity is the number one health concern among parents in the United States, topping drug abuse and smoking. How is it diagnosed? How is it treated? To discuss this epidemic, host Dr. Prathima Setty welcomes Dr. Janine Rethy, pediatrician and director of community medicine at Healthworks of Northern Virginia. Dr. Rethy has won numerous awards and grants in response to the obesity epidemic. She is founder and directs the Healthworks PALS program, a multi-disciplinary community-centered approach to pediatric obesity.
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Host: John J. Russell, MD
In 1998 Andrew Wakefield, a British gastroenterologist with a history of self-promotion, published a paper with a shocking allegation: the measles-mumps-rubella vaccine might cause autism. The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. Yet despite the numerous studies that failed to find any link between childhood vaccines and autism, it has since been popularized by media personalities, and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. In The Panic Virus: The True Story Behind the Vaccine-Autism Controversy, author Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is?
Host: Paul Rokuskie
It has been over 10 years since the Diagnostic Statistical Manual of Mental Disorders, or DSM, has been updated and released in its fifth edition. There has been much anticipation and controversy over the many changes that have been incorporated, and among the most carefully scrutinized are those pertaining to autism spectrum disorder. Joining host Paul Rokuskie to discuss important DSM-V updates in the diagnosis and classification of autism are Dr. David Kupfer, Chair of the DSM-V Taskforce, and Dr. Catherine Lord of the Neurodevelopmental Disorders Workgroup.
Host: Paul Rokuskie
Applied Behavioral Analysis (ABA) is considered a safe and effective treatment approach for children with Autism Spectrum Disorder, but it is often misconceived by parents and teaching professionals in school settings. Joining host Paul Rokuskie to discuss research behind ABA techniques for increasing positive, useful behaviors and reducing those that may cause harm or interfere with learning is Dr. Gina Green, Executive Director at the Association of Professional Behavioral Analysis.
Host: Paul Rokuskie
Autism Spectrum Disorders have major impacts on three important building blocks of an individual's social skills: interactions, communications, and interests. Joining host Paul Rokuskie to discuss methods that clinicians can use to address socialization challenges with autistic patients is Carol Gray, Director of The Gray Center for Social Learning and Understanding in Grandville, Michigan.
Host: Paul Rokuskie
Autism Spectrum Disorder is one of the greatest medical and social challenges facing not only the United States, but the entire world. As the medical community focuses resources on finding the causal factors for autism and delivering viable treatment options for patients, key specialists in translational neurobiology research are leading the charge. Dr. Robert Ring, Vice President and Head of Translational Research for Autism Speaks, the world's leading autism science and advocacy organization, speaks with host Paul Rokuskie about current advances in understanding, diagnosis, and treatment for this disorder.
Host: Paul Rokuskie
Host Paul Rokuskie is joined by Mercedes Ignasiak and Vanessa Vega, both parents of children with autism. Their conversation centers on the impact of this disease on entire families, how parents manage autism at home, and their roles as key contributors to the healthcare team.
Host: Boston Children's Hospital
Taking on Tomorrow: A National Pediatric Innovation Summit + Awards 2013
When it comes to health care, what matters in pediatrics matters for everybody. Pediatrics has a front-row seat in the health care arena: Diseases of adulthood often have their origins in childhood, and pediatrics is well positioned to spot problems, head them off and lead the search for safe and lasting solutions. That makes pediatric care a hotbed for innovation, from personal genomics to digital apps and telemedicine programs that keep kids out of the hospital.
Taking on Tomorrow will convene top thought leaders to distill the successes and address the tough challenges that continue to confront pediatric health care. Leading clinicians, scientists, engineers and leaders in industry, private equity and health care policy will engage in panels and "town hall" discussions-collectively taking on problems that no single organization, agency or company can solve alone.
Register today to join this dynamic dialogue, connect with professionals in other sectors and help transform medicine for the future - www.takingontomorrow.org/reachmd
Sponsored by
Host: Peter S. Jensen, MD
What do we know about depression? And, what is going on at the level of the neuron? Traditional treatments have had impressive results in children with depression. But, why does efficacy of treatment vary in children? Host Dr. Peter Jensen welcomes Dr. Paul Croarkin, Assistant Professor of Psychiatry at Mayo Clinic, to answer these questions and discuss recent clinical trials, child and adolescent psychopharmacology and transcranial magnetic stimulation (TMS) and brain stimulation modalities.
Download and listen today!
Host: Peter S. Jensen, MD
Guest: Lynn Wegner, MD
Host Dr. Peter Jensen welcomes Dr. Lynn M. Wegner, a developmental-behavioral pediatrician and chief of the UNC Division of Pediatric Developmental-Behavioral Medicine at North Carolina Children's Hospital. Dr. Wegner shares her perspective on primary care clinicians finding, assessing and managing depression in their pediatric patients.
Please click here to download the tools that may help you learn more about children's emotional and behavioral disorders.
Sponsored by
Host: Peter S. Jensen, MD
Host Dr. Peter Jensen welcomes Dr. Martin Stein, Professor of Pediatrics at the University of California, San Diego, and Rady Children's Hospital, San Diego. Dr. Stein's academic interest has been the development of methods to incorporate concepts about child development and behavioral pediatrics into educational models, as well as the practice of primary care pediatrics. In this program, Dr. Stein will review the most commonly used stimulants in treating ADHD and how to best manage manage their side effects, specifically weight loss, weight gain, headaches, and sleep onset problems.
Please email all questions and comments to info@reachmd.com.
Host: Peter S. Jensen, MD
Host Dr. Peter Jensen welcomes Dr. Christopher Wall, a pediatric and adolescent psychiatrist from the Mayo Clinic, to discuss pediatric mood disorders. Dr. Wall shares his research on the topic of pharmacogenomic utility in pediatric psychopharmacology, as well as his collaboration in the development of a pediatric bipolar disorder biobank that adds to the understanding of this complex mood illness.
Download and listen in on this engaging conversation!
Host: Peter S. Jensen, MD
Depression in children and teenagers is a common problem and the statistics of depression in this group is very high approximately 15%. Host Dr. Peter Jensen welcomes Dr. John Huxsahl to discuss the EMERALD project, which is innovative care team model at Mayo Clinic that includes a psychiatrist, registered nurse, behavioral health manager, and social worker. The EMERALD projects is designed to help primary care physicians become more comfortable in identifying and diagnosing depression in adolescent patients and in managing their care. Dr. Huxsahl explains the importance of monitoring symptoms of depression in the primary care offices, reviewing medications and adverse effects and setting behavioral activation goals. Dr. Huxsahl is an Assistant Professor of Psychiatry, Head of Child and Adolescent Psychiatric Services and the Director of Child Mood Disorders Clinic at Mayo Clinic.
Host: Peter S. Jensen, MD
In this Ask the Expert edition of Updates from Mayo Clinic, host Dr. Peter Jensen addresses questions from his colleagues in the area of bullying and aggression in pediatric and adolescent patients. Children diagnosed with Attention-Deficit /Hyperactivity Disorder can present with numerous difficulties in several areas of life, and particularly within the social realm. ADHD is more prevalent among children identified as bullies and victims , and research indicates that certain interpersonal problems these children experience, also increase the risk for involvement in bully /victimization behaviors. Tune in as Dr. Jensen answers your questions and much more.
And, if you would like to participate in future "Ask the Expert" programming for this or other programs on ReachMD, please send your questions to info@reachmd.com.
Guest: Timothy Lineberry, MD
Host: Peter S. Jensen, MD
A difficult topic that faces the health care community is addressing suicidality with our patients, especially our adolescent patients. In the United States, suicide is one of the 10 leading causes of death; and, in young adults, it is one of the 3 leading causes of death. Timothy Lineberry, MD, addresses this important topic, recent research and data, and crisis action planning.
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Guest: David J. Katzelnick, MD
Host: Peter S. Jensen, MD
Research shows that almost three-fourths of patients who have mental health are treated in primary care settings. Host Dr. Peter Jensen welcomes his colleague, Dr. David Katzelnick, Associate Professor of Psychiatry at Mayo Clinic and Chair of the Division in Integrated Behavorial Health. Dr. Katzelnick explains and discusses the integration of evidence-based mental health treatmensts and expertise for physicians who are in primary care.
Host: Peter S. Jensen, MD
Guest: Gabrielle A. Carlson, MD
Host Dr. Peter Jensen welcomes Gabrielle A. Carlson, MD, Professor of Psychiatry and Pediatrics and Director of Child and Adolescent Psychiatry at Stony Brook University School of Medicine in Stony Brook, NY. Dr. Carlson will discuss the current controversies in diagnosing pediatric bipolar disorders, recommended treatment options and guidance in patient dialogue for primary care colleagues.
Tune in and listen!
Guest: Stephen Whiteside, PhD, LP
Host: Peter S. Jensen, MD
Host Dr. Peter Jensen welcomes Stephen Whiteside, PhD, LP, who will discuss pediatric anxiety disorders. Dr. Whiteside will address the prevalence of anxiety disorders in adolescents, the ability of physicians to identify those pediatric patients who may have anxiety disorders, as well as, the benefits of treatement and therapy options.
Tune in and listen to the discussion!
Host: Matt Birnholz, MD
This Prova Education program, presented by Deborah O'Connor PhD, RD, Professor of Pediatrics at the University of Toronto and Director of Clinical Dietetics at The Hospital for Sick Children, has been developed from the May 2011 live meeting in Denver, CO, A Month in the Life: Achieving Recommended Nutritional Status in Preterm, Low Birth Weight Infants Before, During and Beyond Hospital Discharge.
This program discusses preterm infant nutritional needs beginning at the NICU, the complexities of ensuring good nutritional status, and monitoring care through the transition to home and community settings. Through a review of new evidence-based information, physicians can apply practices that will support nutrition decisions for pre-term and low birth weight infants upon admittance to the NICU and continue through transitions.
Host: Matt Birnholz, MD
This Prova Education program, presented by Jae H. Kim, MD, PhD, Assistant Professor of Pediatrics at University of California, San Diego, has been developed from the May 2011 live meeting in Denver, CO, A Month in the Life: Achieving Recommended Nutritional Status in Preterm, Low Birth Weight Infants Before, During and Beyond Hospital Discharge.
This program discusses preterm infant nutritional needs beginning at the NICU, the complexities of ensuring good nutritional status, and monitoring care through the transition to home and community settings. Through a review of new evidence-based information, physicians can apply practices that will support nutrition decisions for pre-term and low birth weight infants upon admittance to the NICU and continue through transitions.
Host: Matt Birnholz, MD
This Prova Education program, presented by Eyla G. Boies, MD, FAAP, FABM, Clinical Professor of Pediatrics at University of California, San Diego, has been developed from the May 2011 live meeting in Denver, CO, A Month in the Life: Achieving Recommended Nutritional Status in Preterm, Low Birth Weight Infants Before, During and Beyond Hospital Discharge.
This program discusses preterm infant nutritional needs beginning at the NICU, the complexities of ensuring good nutritional status, and monitoring care through the transition to home and community settings. Through a review of new evidence-based information, physicians can apply practices that will support nutrition decisions for pre-term and low birth weight infants upon admittance to the NICU and continue through transitions.
Host: Matt Birnholz, MD
Beyond the inherent moral implications, child abuse is a crime, a tragedy, and a significant public health burden. In the United States, approximately 1 in 5 children have experienced some form of maltreatment, including physical and sexual abuse and the often overlooked danger of neglect. Child maltreatment results in over 1,700 deaths each year; however, the negative health effects reach well beyond these fatalities. In addition to physical injuries, maltreatment causes stress that can disrupt brain development. Thus, children who are maltreated are at higher risk for adult health problems such as alcoholism, smoking, depression, drug abuse, obesity, high-risk sexual behaviors, suicide, and certain chronic diseases.
This session of Public Health Grand Rounds from the CDC focused on the epidemiology and costs of child maltreatment, the need for partnerships, and the potential for policy interventions to combat this urgent public health issue.
This is Part 1 of a lecture in three parts.
Part 2 >>
Part 3 >>
To view the complete video recording of this and other CDC Public Health Grand Rounds sessions, visit http://www.cdc.gov/about/grand-rounds/
And for those interested in receiving continuing education credits for the live broadcasts of Public Health Grand Rounds, register at http://www2a.cdc.gov/TCEOnline
CDC's …
Host: Matt Birnholz, MD
Presenting this session of Grand Rounds is Dr. Leslie Boyer, founding director of the VIPER Institute in the College of Medicine at the University of Arizona.
This is Part 1 of a lecture in three parts.
Part 2 >>
Part 3 >>
To view the complete video recording of this and other Grand Rounds sessions from the University of Arizona College of Medicine, visit their website.
Host: Matt Birnholz, MD
This year's meeting of the American Academy of Allergy, Asthma & Immunology (AAAAI), held in San Francisco over March 18th through the 22nd, attracted over 7,000 participants from around the world, including clinicians, academics, allied health professionals, and others interested in allergic and immunologic disease. The conference highlighted recent advances in allergy and immunology research, with presentations also focusing on other developments in allergy, asthma, and immunologic diseases.
Host: Gary Epstein
Guest: Kimberly Avila Edwards, MD
An obese child has an 80 percent chance of staying obese throughout their lifetime. The children that Texas pediatrician Dr. Kimberly Avila Edwards saw in her practice, combined with statistics showing her home state had an even higher childhood obesity rate than the already-high national average, prompted Dr. Avila Edwards to leave her general pediatric practice to devote herself to the fight against childhood obesity. In her conversation with host Gary Epstein, Dr. Avila Edwards notes she was completely unprepared by medical school to deal with obesity, and its related health problems, in children. They discuss Dr. Avilla Edwards' efforts to collaborate, and in some cases create her own resources, in order to work with children and their families.
This week's guest was nominated by the
Host: Matt Birnholz, MD
Recognizing the respiratory manifestations of neuromuscular disease in children is a critical first step toward protecting their survival and improving their quality of life. In this session of Grand Rounds from the University of Arizona College of Medicine, participants learn about the art of assessing respiratory problems in these children, and the treatment options available for optimizing long-term management.
Presenting this session of Grand Rounds is Dr. Cori Daines, pediatric pulmonologist and associate professor of pediatrics at the University of Arizona College of Medicine. Dr. Daines is director of the pediatric bronchoscopy program, and co-director of the Tuscon Cystic Fibrosis Center.
This is Part 1 of a lecture in three parts.
Part 2 >>
Part 3 >>
To view the complete video recording of this and other Grand Rounds sessions from the University of Arizona College of Medicine, visit their website.
Guest: Tom Baranowski, PhD
Host: Steven Edelman, MD
How are video games showing promise as a behavior change strategy to improve children's diets? Newly-funded video-game programs are specifically designed to lower risk of type 2 diabetes and obesity in children. Join host Dr. Steven Edelman and his guest, professor of pediatrics at Baylor College, Dr. Tom Baranowski as they discuss innovative approaches to behavior change incorporating video games for children. Watch trailers for these games at www.archimage.com.
Guest: Alberto Hayek, MD
Host: Steven Edelman, MD
Diabetes research is the cornerstone for new opportunities in the treatment of patients living with diabetes. How will the newly formed Pediatric Diabetes Research Center serve this goal? Join guest host, certified diabetes educator Janice Baker and Dr. Alberto Hayek, professor of pediatrics and co-director of the UC San Diego's Pediatric Diabetes Research Center, as they discuss the need for collaboration in both biochemistry, molecular and cell-based therapies for the treatment of diabetes.
Guest: G. Alexander Fleming, MD
Host: Bruce Bloom, DDS, JD
Researchers are looking at hundreds of ways to treat and cure type one diabetes. Most of the advances so far have come in newly diagnosed children. Is there anything on the horizon to help adults with established type one diabetes? Dr. Alexander (Zan) Fleming, chairman and chief medical officer of Exsulin, joins host Dr. Bruce Bloom to discuss the new therapies for reversing established diabetes.
Guest: Carolyn Paris, MD
Host: Mary Leuchars, MD
Improved living conditions and hygiene may be contributing to the rise of type 1 diabetes in children, but does the "hygiene hypothesis" fully explain the onset of type 1 diabetes in this population? What factors might explain the increased incidence of type 1 diabetes among pediatric patients in the US, Sweden and Finland, in particular? Dr. Carolyn Paris, pediatrician and emergency medicine specialist at the Center for Clinical and Translational Research at Seattle Children's Hospital, explores the indirect evidence that examines environmental influences in the development of type 1 diabetes in children. Dr. Mary Leuchars hosts.
Host: Matt Birnholz, MD
Hear highlights from the American Academy of Pediatrics National Conference and Exhibition, held October 2-5, 2010, in San Francisco. This year’s conference focused on advances in the health, safety, and well-being of infants, children, adolescents and young adults, attracting over 8 thousand participants from around the world.
Guest: Samuel Gidding, MD
Host: Alan S. Brown, MD, FACC, FAHA, FNLA
What age does atherosclerosis and increased risk of heart attacks begin? Can children be at risk, and under what conditions should children's cholesterol levels be checked? Host Dr. Alan Brown discusses lipids in pediatric patients with Dr. Sam Gidding, of the Nemours Cardiac Center at the Alfred I. duPont Hospital for Children in Wilmington, Delaware, and professor of pediatrics at the Jefferson Medical College.
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Host: Jay Goldstein, MD
Guest: Stanley Cohen, MD
What types of small bowel abnormalities are most common among pediatric patients? How can physicians investigate suspected small bowel disease or gastrointestinal (GI) bleeding in our younger patients? Dr. Stanley Cohen, gastroenterologist at the Combined Center for Inflammatory Bowel Disease and Children's Center for Digestive Health Care at Children's Healthcare of Atlanta, and adjunct clinical professor of pediatrics, Emory University School of Medicine, in Atlanta, Georgia, discusses the roles of CT scans, MRIs and small bowel capsule endoscopy in evaluating pediatric patients with suspected small bowel disease. Dr. Jay Goldstein hosts.
Guest: Elizabeth Sheehan
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
Seven hundred women a day receive medical care inside moldy tents on the grounds of what once was the Grace Children's Hospital in Port-au-Prince, Haiti. But their circumstances will soon improve, thanks to an innovative nonprofit organization, Containers to Clinics, launched by PA Elizabeth Sheehan. Containers to Clinics converts empty shipping containers into state-of-the-art medical facilities in rural areas where electricity, running water and quality medical care are hard to find. Lisa Dandrea Lenell talks to Sheehan about where the idea for Containers to Clinics came from, what it takes to set up a container and what the organization is doing to help the people of Haiti following the devastating earthquake in January 2010.
Host: Janet Wright, MD
Guest: Paul Heidenreich
Sudden cardiac death among high school or college athletes is rare but tragic, and is jarring to families, friends and communities. What additional measures can physicians take to prevent sudden cardiac death among these students? Current guidelines for screening of young athletes in the U.S. do not include electrocardiography but should they, especially in light of recent Italian research about the efficacy of EKG screenings in preventing sudden cardiac death in this population? Dr. Paul Heidenreich, associate professor of medicine (cardiovascular) and associate professor by courtesy of health research and policy, at the Veterens Affairs (VA) Palo Alto Health Care System, and fellow of the Center for Health Policy and the Center for Primary Care and Outcomes Research at Stanford University, weighs the benefits and risks of widespread use of ECG's in the screening of young athletes. Is there a reasonable cost effectiveness value to adding ECG to routine screening for these patients, compared to a routine medical history and physical exam? How should physicians discuss the value of ECG screening with young adult athletes and their parents? Hosted by Dr. Janet Wright.
Produced in Cooperation with <img title="American College of Cardiology" src="/media/images/cmsimages/Series/ACC_Seal_150.jpg" alt="American College of Cardiology" width="150" height="150" border="0" …
Guest: Suleena Kalra, MD
Host: Lee Freedman, MD
Primary and secondary amenorrhea can have various underlying causes among adolescents, including polycystic ovarian syndrome (or PCOS), thyroid disease, and atypical body weight. What types of behavior and lifestyle modifications should be the first steps for adolescent patients with irregular menstruation? Dr. Suleena Kalra, assistant professor in the department of obstetrics and gynecology at Penn Medicine, discusses ways to regulate periods among adolescent patients and protect their future fertility. How significant a role might stress play in amenorrhea among these patients? Dr. Lee Freedman hosts.
Produced in Cooperation with
Guest: Sally Ward, MD
Host: Jerome Lisk, MD
Dr. Sally Ward, who heads the division of pediatric pulmonology and is the medical director of the sleep laboratory at Los Angeles's Children's Hospital, talks to host Dr. Jerome Lisk about the physiological changes in children who experience sleep apnea and other sleep problems. They discuss how some sleep problems come about, how being overweight contributes, and how to help pediatric patients battling obesity and sleep problems.
Guest: Berish Rubin, PhD
Host: Bruce Bloom, DDS, JD
Only a few years ago familial dysautonomia (FD) was a fatal disease, but some "Rediscovery Research" from the FD lab at Fordham University in Bronx, New York, is turning this killer into a chronic manageable disease. What have we learned from familial dysautonomia research, and how might this help patients with other diseases? Joining host Dr. Bruce Bloom to provide an update on current FD research and treatment is Dr. Berish Rubin, professor in the department of biological sciences and head of the laboratory for familial dysautonomia research at Fordham University.
Guest: Philip Zeitler, MD, PhD
Host: Steven Edelman, MD
The emergence of type 2 diabetes in both children and adolescents suggests a relationship between insulin sensitivity and puberty. What are we learning from recent studies and clinical research? Join host Dr. Steven Edelman and his guest, professor of pediatrics at the University of Colorado, Dr. Philip Zeitler as they discuss recent studies and clinical data that may shed light on this relationship.
Guest: Lynne Mofenson, MD
Host: Maurice Pickard, MD
Although HIV transmission through breast milk is a significant global health issue, many mothers and their babies depend on breastfeeding for survival. About 90% of children who become infected with HIV each year are in sub-Saharan Africa. What therapeutic interventions are recommended for mothers with HIV in order to prevent transmission of the virus to their babies? Dr. Lynne Mofenson, chief of the pediatric, adolescent and maternal AIDS branch at the National Institute of Child Health and Human Development, at the National Institutes of Health in Rockville, Maryland, discusses two exciting new developments found to reduce the risk of HIV transmission from mothers to their babies in places where replacement feeding for infants isn't available. Hosted by Dr. Maurice Pickard.
Guest: Jonathan Fanaroff, MD, JD, FCLM, FAAP
Host: Maurice Pickard, MD
About 500,000 births in the US every year are pre-term, making premature delivery far from uncommon. And with the increasing survival of pre-term infants, parents and caretakers are having to make more difficult decisions then ever before. How are prenatal consultations beneficial, and when is the most appropriate time for physicians to have a prenatal discussion with parents? Dr. Jonathan Fanaroff, associate medical director of the Neonatal Intensive Care Unit at Rainbow Babies & Children's Hospital and director of the Rainbow Center for Pediatric Ethics in Cleveland, Ohio, suggests strategies for approaching this type of conversation with parents, and emphasizes the role of these discussions in strengthening the relationship and trust between physicians and parents. Dr. Maurice Pickard hosts.
Guest: Anthony Alessi, MD
Host: Matt Birnholz, MD
Host: Michael Greenberg, MD
In this show, our hosts get an update from ReachMD host Dr. Anthony Alessi, from Haiti, six months after the earthquake. And, they question Dr. Andrew Wakefield, widely-known for his controversial and discredited research linking the MMR vaccine with autism. He has a new book about his experiences, Callous Disregard: Autism and Vaccines: The Truth Behind a Tragedy.
Guest: Seth Corey, MD, MPH
Host: Bruce Bloom, DDS, JD
Physician scientists keep one foot in clinical care and the other in the lab, hoping to bridge that gap to help patients. Are breakthroughs on the horizon? Dr. Seth Corey, the Sharon Murphy and Steven Rosen Professor of Cancer Biology and Chemotherapy at Northwestern University Feinberg School of Medicine and director of oncology research at Children's Memorial Hospital and the Robert H. Lurie Comprehensive Cancer Center, joins host Dr. Bruce Bloom to discuss his research on repurposing safe pharmaceutical and botanical medicines for relapsed pediatric cancers.
Host: Janet Wright, MD
Guest: Nathalie Farpour-Lambert, MD
Childhood obesity is a significant health concern in the US and worldwide. How does obesity impact a child's cardiovascular function and influence future risk of heart disease? Dr. Nathalie Farpour-Lambert, head of the Pediatric Exercise Medicine and Obesity Care Program in the department of pediatrics at the University Hospitals of Geneva in Switzerland, discusses new findings about the effect of a modest amount of physical activity in improving blood pressure, arterial function and arterial wall thickness in obese children. How can clinicians overcome the biggest challenges in encouraging a healthy lifestyle for their pediatric patients?
Produced in Cooperation with
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
Guest: Rear Admiral Michael Milner, PA-C
Surgeon General Dr. Regina Benjamin has two new priorities: to combat childhood obesity and to encourage all Americans to put their health histories online. So how do practitioners get involved in these new government initiatives? Rear Admiral Michael Milner, assistant surgeon general and chief of the US Public Health Services Corps, joins host Lisa Dandrea Lenell to get the message out about the latest technology allowing patients to easily share their medical records with doctors and family members, as well as getting kids to start exercising and eating healthily.
Guest: Stephen Ponder, MD, CDE
Host: Steven Edelman, MD
The emergence of type 2 diabetes in children and adolescents over the past 20 years represents a shift in pediatric chronic disease. Join host Dr. Steven Edelman and his guest, professor of pediatrics and director of the Children’s Diabetes and Endocrine Center of South Texas at Driscoll Children’s Hospital, Dr. Stephen Ponder, as they discuss key challenges in both diagnosis and medical management of this group.
Host: Mark Chyna, MD
Tune in for highlights from the conference floor, at the most recent American Academy of Pediatrics National Conference and Exhibition. This year's meeting took place October 17th through the 20th, 2009, in Washington, DC.
Host: Janet Wright, MD
Guest: Gerard R. Martin, MD
Although congenital heart disease is one of the most common birth defects, its complexity has made the accumulation of an evidence base a challenge. The IMPACT registry, which stands for improving pediatric and adult congenital treatments, has been created to fill this information gap, and it is hoped that these data will provide clinical evidence to help guide treatment for pediatric heart disease. Dr. Gerard Martin, senior vice president for the Center for Heart, Lung and Kidney Disease and co-director of the Children’s National Heart Institute at Children’s National Medical Center, discusses how the IMPACT registry might help improve quality outcomes for our younger patients with congenital heart disease. Dr. Janet Wright hosts.
Guest: Emil Kakkis, MD, PhD
Host: Bruce Bloom, DDS, JD
Host Dr. Bruce Bloom welcomes Dr. Emil Kakkis, an advisor at BioMarin Pharmaceutical Inc. and author of numerous published articles on mucopolysaccharidosis I, or MPS I, to discuss current treatment options. They discuss the benefits and risks of enzyme replacement therapy with laronidase.
Don't miss these other programs on MPS I, with host Dr. Bruce Bloom:
Challenges in Management of MPS I
Immune System Irregularities in Lysosomal Storage Disorders
Musculoskeletal Aspects of MPS I: Diagnosis and Management Considerations
Host: Janet Wright, MD
Guest: Mostafa Youssef, MD
This week on Heart Matters, we'll explore the terrain of cardiovascular care in the Kingdom of Saudi Arabia with one of the country's leading experts, Dr. Mostafa Youssef, founding director of the Prince Salman Heart Center at King Fahad Medical City in Riyadh. It is a country with vast cultural differences compared to the Western world, and yet we find physicians in Saudi Arabia treating many of the same cardiac conditions that we see in the United States. Host Dr. Janet Wright talks with Dr. Youssef about the challenges of treating a very young population with a high incidence of risk factors and distinctive pathologies, efforts parallel to those in the U.S. to develop information technologies in health care, as well as opportunities to connect with global cardiovascular leaders to continue to improve the quality of care and health outcomes across the country.
Guest: Susan Phillips, MD
Host: Steven Edelman, MD
The incidence of diabetes is increasing per year in the US and globally. The trend data suggests that obesity may be driving autoimmune beta cell failure. Some have questioned whether excess obesity or adiposity might be playing a role in this increased incidence of type 1 diabetes or whether healthcare professionals are not recognizing type 2 diabetes in youth. Join host Dr. Steven Edelman and his guest, pediatric endocrinologist and clinical researcher, Dr. Susan Phillips, as they discuss the challenges facing healthcare professionals in the diagnosis and treatment of diabetes in childhood.
Host: Jack Lewin, MD
Guest: Nancy Brown
Decisions our young patients make now can have metabolic consequences for the rest of their lives. It's hard to overstate, not only how crucial it is that we reduce the incidence of childhood obesity, but also how difficult it has been for us to turn the corner on this issue. These concurrent themes are central to a campaign put forth by the American Heart Association (AHA) that aims to make major progress on childhood obesity in the years to come. Host Dr. Jack Lewin gets the details on this campaign during his conversation with the AHA's chief executive officer, Nancy Brown. How is the AHA partnering with schools to empower kids to make healthier decisions about their consumption habits and lifestyle choices? How can we help fellow clinicians move beyond the feeling that their efforts to reduce childhood obesity aren't having the desired effect?
Guest: Paul Ehrmann, DO
Host: Mary Leuchars, MD
The general public and medical community alike face a difficult question on childhood obesity: are we witnessing the development of a supersized generation of children? Could this generation even fail to outlive their parents? Dr. Paul Ehrmann, a family practice physician and award-winning community activist, argues that this potential outcome is a reality. Host Dr. Mary Leuchars overviews Dr. Ehrmann's leading efforts with the novel Children's Health Initiative Programs (CHIPs) to counter national trends toward 'Generation XL' at the community level.
Guest: Barry Sarvet, MD
Host: Jennifer Shu, MD, FAAP
Research tells us that roughly one in 20 teenagers in the United States suffers from clinical depression. The problem is most are not receiving treatment because they haven't been diagnosed. In a recent report, the US Preventive Services Task Force issued a recommendation for the routine screening of all adolescents in the primary care setting, even if they don't show signs of depression. Is this recommendation practical? And, can our healthcare system accommodate the likely increase in teens who would subsequently become candidates for mental health treatment? Dr. Barry Sarvet, chief of child and adolescent psychiatry at Baystate Medical Center in Springfield, Massachusetts, joins host Dr. Jennifer Shu for a discussion of the pros and cons of routine depression screening for teenagers.
Guest: Wesley Burks, MD
Host: Lee Freedman, MD
Peanut allergy is an increasing public health concern in the United States. Children with peanut allergy may remain allergic for life, unlike children with more often outgrown allergies to milk or egg. Dr. Wesley Burks, professor and chief of the division of pediatric allergy and immunology at Duke University Medical Center, describes recent success with peanut immunotherapy in a few groups of children. Do these studies provide hope for all patients with peanut allergy, including adults? Dr. Lee Freedman hosts.
Guest: Subodh Kumar Singh, MD
Host: Maurice Pickard, MD
The Oscar-winning documentary film Smile Pinki depicts a little girl who undergoes a cleft palate operation, and experiences a very changed life as a result. Host Dr. Maurice Pickard welcomes Pinki’s surgeon, Dr. Subodh Kumar-Singh, director and chief of plastic surgery at GS Memorial Plastic Surgery Hospital in Varanasi, India. Dr. Kumar-Singh also works with the non-profit organization Smile Train, which provides cleft surgeries to underserved children worldwide. Tune in to learn more about the significant problem of cleft lip and palate in India, and worldwide.
Guest: Robert Pass, MD
Host: Jennifer Shu, MD, FAAP
Congenital cytomegalovirus (CMV) infection causes auditory, cognitive and neurologic impairment in thousands of infants each year in the United States. Recognition of infection in pregnant women is difficult because CMV often produces few symptoms, and antiviral treatment during pregnancy may have toxic effects. Could a new experimental vaccine hold the key to preventing maternal CMV infection during pregnancy and decrease the incidence of congenital CMV infection and its sequelae? Host Dr. Jennifer Shu evaluates the progress toward a CMV vaccine with Dr. Robert Pass, professor of pediatrics and microbiology at the University of Alabama at Birmingham School of Medicine. Dr. Pass also explains the proposed mechanism of action for the vaccine.
Guest: Christina Robohm, PA-C
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
How does a PA handle the situation when a parent does not want to vaccinate their child? Christina Robohm, physician assistant and associate professor of pediatrics at the University of Colorado at Denver, tackles this growing issue with host Lisa Dandrea Lenell. The two discuss how PAs make sure parents receive accurate information in order to make an informed decision whether or not they want their children to receive vaccinations, the pros and cons of not vaccinating, and what it means for other children around them and the community at large. They also look at the controversy over vaccinations and autism.
Guest: Paul Offit, MD
Host: Jennifer Shu, MD, FAAP
Most parents support the immunization of their kids according to the recommended vaccine schedule. But increasing numbers are choosing to forgo this routine entirely or follow an alternative vaccine schedule. How are these vaccine practices impacting the health of our young patients and more broadly, the health of the general public?Host Dr. Jennifer Shu examines the key questions surrounding the alternative vaccine schedules and how to guide young patients and their families through this process, with Dr. Paul Offit, chief of the division of infectious diseases and director of the Vaccine Education Center at the Children's Hospital of Philadelphia, and the Maurice R. Hilleman Professor of Vaccinology at the University of Pennsylvania School of Medicine.
Guest: David Fleischer, MD
Host: Jennifer Shu, MD, FAAP
Wheat, eggs, milk, peanuts and other nuts, soybeans and seafood: all of these can be an integral part of a balanced, healthy diet for growing children. Instead, many are off-limits for an increasing number of children diagnosed with food allergies. Though the rise in food allergies is certainly worrisome, we're learning that some food allergies may actually be misdiagnosed. Host Dr. Jennifer Shu welcomes Dr. David Fleischer, assistant professor of pediatrics at the University of Colorado School of Medicine and National Jewish Health in Denver, for a conversation about how we can improve our capacity to accurately assess food allergies, and help many of our young patients tolerate, or even enjoy, a wider range of food. Starting with a clinical history, what kind of workup should be done before patients are referred to an allergist? How should allergen-specific antibody blood tests be incorporated into this process?
Guest: Captain Timothy Harrelson
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
For his efforts in Afghanistan stabilizing victims wounded in Taliban offensives and providing clean water to families, Cpt. Timothy Harrelson was awarded the Bronze Star. Cpt. Harrelson talks with host Lisa Dandrea Lenell about his lifesaving work with malnourished children in Qalat, Afghanistan. Cpt. Harrelson was involved in the formulation of nutrition that reduced the pediatric mortality rate in Qalat by 25 percent.
Guest: Bernard Cohen, MD
Host: Michael Greenberg, MD
Hemangiomas are common in infants, and often appear within the first few weeks of life. Although many infant hemangiomas are unsightly but regress after a few months, others can be large and disfiguring. Until recently, there have been no ideal treatment options, but there has been recent success using propranolol to treat infant hemangiomas. Host Dr. Michael Greenberg explores this exciting new treatment with Dr. Buddy Cohen, professor of dermatology and pediatrics at Johns Hopkins University School of Medicine.
Guest: Douglas Nordli, MD
Host: Jennifer Shu, MD, FAAP
The ketogenic diet has been used as a therapy for refractory epilepsy in children since the 1920's. It was only recently, however, that a randomized, controlled study confirmed it to be effective in reducing seizures. Is there a role for the ketogenic diet as first-line therapy for epilepsy? Which patients stand to benefit the most from this diet, and what are some of its potential adverse effects? Dr. Douglas Nordli, associate professor of neurology and pediatrics at Northwestern University's Feinberg School of Medicine, and the Lorna S. and James P. Langdon Chair of Pediatric Epilepsy, offers details on this trial and explores mechanisms through which we may generate more timely results in our research for patients with epilepsy. Dr. Jennifer Shu hosts.
Guest: David P. Skoner, MD
Host: Ketan Sheth, MD, MBA
Is there evidence that suggests corticosteroids used to treat asthma might affect growth? Are growth effects from using inhaled or intranasal steroids to control asthma or allergic rhinitis a significant concern? Dr. David Skoner, professor of pediatrics at the Drexel University College of Medicine, discusses the challenges of evaluating the systemic effects of these medications, and suggests what physicians can do to minimize the risk of growth effects when using corticosteroids. Dr. Ketan Sheth hosts.
Guest: Miriam Vos, MD, MSPH
Host: Larry Kaskel, MD
Non-alcoholic fatty liver disease (NAFLD) is increasingly common among our young obese patients, a population for which cardiovascular disease and diabetes is a significant concern. Can measured levels of liver fat serve to help us gauge future risk for metabolic consequences in children? Host Dr. Larry Kaskel welcomes pediatric hepatologist, Dr. Miriam Vos, assistant professor in the division of gastroenterology at Emory University School of Medicine, to discuss the challenge of encouraging a young child and their family to develop habits that will promote the decline of the child's NAFLD. Dr. Vos also explores the possibility that body shape may be an important clue in the diagnosis of NAFLD, as well as current efforts to generate more accurate markers to quantify liver fat reduction during treatment.
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Guest: Andrea Doria, MD, PhD, MSc
Host: Jason Birnholz, MD
In 1888, William Osler wrote in the Lancet the following: "In patients with suspected acute appendicitis, one should urge towards laparotomy. The indications for surgical interference are not always clear, but in my experience I have been taught that the abdomen is much more frequently left untouched than it should be, and that an operation is too often deferred until practically useless." Clearly, diagnosis of acute appendicitis has come a long way since then. But challenges remain in selecting the safest, most timely, and cost-effective diagnostic modalities for this condition. Dr. Andrea Doria, associate professor in the department of medical imaging at the University of Toronto School of Medicine, clarifies the use of ultrasound versus CT for evaluation of acute appendicitis in children. Dr. Jason Birnholz hosts.
Guest: Caroline Hall, MD
Host: Jennifer Shu, MD, FAAP
Respiratory syncytial virus (RSV) is a well-known cause of hospitalization in infants, but new research suggests the burden of illness may be more substantial than previously recognized in healthy, older children as well. Investigators estimate over two million children under the age of five require medical treatment for RSV each year. Because it can be difficult to prevent and treat RSV infections, is there a role for a vaccine against the illness? Host Dr. Jennifer Shu welcomes Dr. Caroline Hall, professor of pediatrics and medicine at the University of Rochester School of Medicine and Dentistry, to explore these questions. Dr. Hall also explains how the characteristics of the virus and its mechanisms of transmission contribute to its proliferation.
In an issue of the Journal, Boucek et al. reported on three cases of heart transplantation from infants who were pronounced dead on the basis of cardiac criteria. Moderator Atul Gawande, of Harvard Medical School; George Annas, of the Boston University School of Public Health; Arthur Caplan, of the University of Pennsylvania; and Robert Truog, of Harvard Medical School discuss key ethical aspects of organ donation after cardiac death.
Guest: Patrick Frias, MD
Host: Jennifer Shu, MD, FAAP
Although sudden death in the pediatric population is rare, there has been a great deal of discussion recently over the possibility of an increase in risk of sudden cardiac death among individuals taking stimulant medication for attention-deficit hyperactivity disorder (ADHD). Dr. Patrick Frias, a pediatric cardiologist and electrophysiologist at Sibley Heart Center Cardiology in Atlanta and associate professor of pediatrics at Emory University School of Medicine, explores this discussion with host Dr. Jennifer Shu. How can we best evaluate our patients' risk for sudden death before initiating medical treatment for ADHD, and how often should we monitor their cardiovascular status?
Host: Jennifer Shu, MD, FAAP
Guest: Michael McConnell, MD
Once mostly a condition of childhood, our patients with congenital heart disease are now living well into adulthood: nearly two million American children and adults are living with a congenital heart defect. What are the special medical needs of our cardiac patients as they transition from adolescence to adulthood? Dr. Michael McConnell, co-director of the adult congenital heart disease clinic at Sibley Heart Center Cardiology in Atlanta and associate professor of pediatrics and medicine at Emory University School of Medicine, reflects upon how our medical system can improve our capacity to care for the growing numbers of adult patients with a congenital heart defect. Dr. Jennifer Shu hosts.
Guest: Robert Findling, MD
Host: Leslie P. Lundt, MD
When schizophrenia first presents in the teen years, patients often have a particularly poor prognosis. What are the best treatments for adolescents? Which medicine is best? Dr. Robert Findling, the Rocco L. Motto, MD, Chair of Child and Adolescent Psychiatry at Case Western Reserve University School of Medicine, talks with host Dr. Leslie Lundt about the long-term effects of medications and new research into treatment of early-onset schizophrenia.
Guest: Darshak Sanghavi, MD
Host: Jennifer Shu, MD, FAAP
In preterm neonates with a patent ductus arteriosus (PDA), the standard of care has been to attempt to close the defect. Yet some experts have asked whether we need to treat PDA in most preemies. If we are to resolve the condition, there are various methods and protocols for treatment and even prevention; how do outcomes for PDA closure vary by treatment strategy? Dr. Darshak Sanghavi, chief of pediatric cardiology and assistant professor of pediatrics at the University of Massachusetts Medical School, lays out the important points of discussion on PDA closure with host Dr. Jennifer Shu.
Guest: J. Herman Kan, MD, FACR
Host: Jason Birnholz, MD
Pre-treatment MRI can eliminate unnecessary diagnostic or surgical procedures for children with suspected musculoskeletal infections. Host Dr. Jason Birnholz and Dr. J. Herman Kan, assistant professor of radiology at Vanderbilt University Medical Center, specializing in pediatric and adolescent radiology, discuss the application of MRIs and the results of his recent study which showed that a significant number of surgeries could be avoided with early MRI evaluation. Tune in to hear the valuable role MRI plays in the evaluation of musculoskeletal infection.
Host: Lauren Streicher, MD
Guest: Michael Holick, PhD, MD
It seems these days patients know more about the benefits of Vitamin D than their physicians. Doctors are soaking up the information and making sure their patients are taking the proper levels of Vitamin D. Dr. Michael Holick, professor of medicine, physiology and biophysics and director of the Bone Health Care Clinic and the Heliotherapy, Light, and Skin Research Center at Boston University Medical Center, joins host Dr. Lauren Streicher to discuss the proper dosage, risk factors, geographical factors and benefits of Vitamin D.
Host: Todd Mahr, MD
Guest: Bradley E. Chipps, MD, FAAP, FACAAI, FAAAAI, FCCP
What criteria are included in the modified asthma predictive index, and how does this index help physicians diagnose young patients with wheezing and coughing? When is bronchoscopy recommended as an important diagnostic tool for evaluating pediatric lower respiratory symptoms? Dr. Bradley Chipps, medical director of respiratory therapy at Sutter Medical Center, reviews how physicians might work up a young patient with these respiratory symptoms, and suggests the most effective treatments. Dr. Todd Mahr hosts.
Guest: James M. Galloway, MD
Host: Maurice Pickard, MD
"Building a Healthier Chicago" is a collaborative initiative to build a model community-wide partnership for health promotion that can be replicated nationwide. Join host Dr. Maurice Pickard as he interviews Dr. James Galloway, assistant US Surgeon General, rear admiral in the US Public Health Service and regional health administrator in Chicago's Region V. They talk about this proactive healthcare model that ultimately aims to prevent chronic disease across the country.
Host: Anthony Alessi, MD
Guest: Don Lewis, MD
How does a pediatric migraine differ from an adult migraine and what does the latest research in the treatment of pediatric migraine tell us? Dr. Don Lewis, professor of pediatrics and neurology at Eastern Virginia Medical School and pediatric neurologist at Children's Hospital of the King's Daughters, joins host Dr. Anthony Alessi to discuss both the nuances and treatments in pediatric medicine.
Guest: Anita Duhl Glicken, MSW
Host: Lisa Dandrea Lenell, PA-C, MPAS, MBA
Anita Glicken, professor of pediatrics and section head of the Child Health Associate/Physician Assistant program at University of Colorado at Denver Health Sciences Center, discusses the scope and admission requirements of this unique physician assistant program. Ms. Glicken explains how the program was started over 30 years ago, long before most physician assistant programs, and prepares its graduates through innovative curriculum to provide comprehensive medical care for people of all ages, emphasizing the care of infants, children, and adolescents. The program is different than most physician assistant programs in that it is a three-year master's level education program and graduates receive specialized training in pediatrics and psychology. Tune in to hear how this unique program is attempting to address the shortages of health care professionals in rural areas and primary care/pediatric practices.
Host: Ketan Sheth, MD, MBA
Guest: Santiago Martinez, MD
What is the relationship between immunity and autism? Do the immune systems of those with autism function differently than the rest of the population? Dr. Santiago Martinez, clinical assistant professor at Florida State University College of Medicine, joins host Dr. Ketan Sheth to discuss the immune systems of autism patients. Is there any evidence that might suggest that autoimmune disorders in mothers can somehow contribute to the development of autism in their children?
Guest: Peter Scheidt, MD, MPH
Host: Jennifer Shu, MD, FAAP
The National Children’s Study will follow the health and development of more than 100,000 children across the United States, starting from before birth until age 21. What do you need to know about this ambitious federally financed project? Dr. Peter Scheidt, medical officer and co-director of the National Children’s Study at the National Institute of Child Health and Human Development, provides the details on this large-scale project: what are its main goals, how is it organized, and what factors will the study examine? Dr. Jennifer Shu hosts.
Guest: Bruce Slaughenhoupt, MD
Host: Jennifer Shu, MD, FAAP
Once considered to be a problem of adulthood, kidney stones are being more regularly documented in children as young as age five. What factors are responsible for the increasing prevalence of this condition, and what can we do to reverse this emerging pattern of childhood kidney stones? Dr. Bruce Slaughenhoupt, assistant professor of urology and co-director of the pediatric kidney stone clinic at the University of Wisconsin School of Medicine, evaluates the clinical implications of this trend with host Dr. Jennifer Shu.
Guest: Roland Sutter, MD, MPHTM
Host: Jennifer Shu, MD, FAAP
The World Health Organization (WHO) is working diligently to eliminate Type 1 poliovirus transmission in endemic countries around the world. Although progress has been made using the trivalent oral poliovirus vaccine, eradication remains elusive. Recent studies have examined the efficacy of a monovalent oral poliovirus vaccine given to newborns: could this monovalent vaccine bring us closer to eradicating poliomyelitis? Dr. Jennifer Shu welcomes Dr. Roland Sutter, coordinator of the research and product development team for the WHO's Global Polio Eradication Initiative, to detail his team's contributions to the evolving body of polio research.
Guest: Christine Ren, MD
Host: Mary Leuchars, MD
When does surgery become the best option for treating obese adolescents? Dr. Christine Ren, founder and director of the New York University (NYU) Program for Surgical Weight Loss and assistant professor of surgery at NYU School of Medicine, addresses this question and identifies target patients for whom surgery is recommended. She also discusses both physical and psychosocial outcomes for adolescents undergoing weight loss procedures, as well as important post-op nutritional complications clinicians should anticipate. Hosted by Dr. Mary Leuchars.
Host: Todd Mahr, MD
Guest: Alan Goldsobel, MD
Cough is one of the most common symptoms but can develop as a symptom of various disorders, from asthma to bacterial infection to gastroesophogeal reflux disorder. How important is the character of a cough in determining the cause in children particularly? Host Dr. Todd Mahr explores cough guidelines and recommendations for children, alon with Dr. Alan Goldsobel, clinical professor in the department of medicine at the University of California San Francisco. At what point is a cough considered chronic, and when should a lingering cough be evaluated in children?
Guest: Mishka Terplan, MD
Host: Lisa Mazzullo, MD
Researchers have no way to determine how significant the problem of substance abuse and pregnancy really is. Very few women will be open and honest when it comes to answering questions about elicit drug use. So how do doctors get their patients the proper help? Dr. Mishka Terplan, an associate professor at the University of Chicago, looks at the issues of universal drug screening for all pregnant women, confidentiality, inpatient and outpatient drug rehabilitation programs and the stigma of being a substance abuser, with host Dr. Lisa Mazzullo.
Guest: Trevor Duke, MD
Host: Shira Johnson, MD
A simple medical device such as an oxygen saturation monitor can make all the difference in a developing country. Dr. Trevor Duke, an intensive care specialist at Royal Children's Hospital in Melbourne, Australia, talks about his study which reduced the death rate from pneumonia in New Guinea by measuring oxygen saturation and administrating oxygen through a concentrator. He and host Dr Shira Johnson discuss this study and his work with the World Health Organization.
Guest: Stephen P. Spielberg, MD, PhD
Host: Bill Rutenberg, MD
Medicines for malaria, tuberculosis, and AIDS are all available for children, but none are formulated specifically for the younger patient population. Recently, the World Health Organization generated an essential drug list for kids. How will they follow up on this effort? Dr. Stephen M. Spielberg, professor of pediatrics, pharmacology and toxicology at Dartmouth Medical School, and principal investigator for the Institute for Pediatric Innovation's Pediatric Pharmaceutical Reformulation Project, joins host Dr. Bill Rutenberg to discuss some of the challenges ahead: formulation, dosing, preservation, delivery and beyond.
Guest: H. Peter Chase, MD
Host: Mary Leuchars, MD
Over 40 children a day are diagnosed with type I diabetes in the United States. What are the clinical management issues pediatric practitioners face today? Joining host Dr. Mary Leuchars is Dr. H. Peter Chase, professor of pediatrics at the University of Colorado Health Sciences Center and past-executive and clinical director of the Barbara Davis Center for Childhood Diabetes in Denver, Colorado. Their subject is type I diabetes in children, from U.S. population trends to keys in clinical recognition, counseling methods for patients and families, and recommendations for follow-up glucose management.
Host: Ketan Sheth, MD, MBA
Guest: Amy Branum, MSPH
The first federal study of food allergies in children by the Centers for Disease Control (CDC) found a steep increase in such allergies over the last decade. What accounts for the rise in diagnoses and hospitalizations? Is the severity of food allergies also increasing? Amy Branum, lead author of the CDC's study and a statistician at the National Center for Health Statistics, illustrates recent figures on pediatric food allergies with host Dr. Ketan Sheth.
Host: Lauren Streicher, MD
Guest: Coleen Kelly, MD
More than 150,000 obese American people undergo bariatric surgery annually. Many of these patients are women who will become pregnant. Dr. Colleen Kelly, a gastroenterologist at Women and Infants Hospital in Providence, Rhode Island, joins host Dr. Lauren Streicher to discuss this growing patient population. The two discuss which surgical option is best for a woman who wants to conceive, along with nutritional guidlines, complications, and of course the health of the baby.
Host: Ketan Sheth, MD, MBA
Guest: Sami Bahna, MD, DrPH
Why are so many people allergic to peanuts? Can people have an allergy to a specific food the very first time they consume it? Both the types of food allergies and the numbers of individuals affected by food allergies increase every year. There are many potential reasons for the rise in food allergies, including the amount of food people consume and the variety of ingredients in what we eat. What other factors are involved in the development of food allergies? Dr. Sami Bahna, Professor of Pediatrics and Medicine as well as the Chief of the Allergy and Immunology Section at Louisiana State University Health Sciences Center, explores the realities of food allergies with host Dr. Ketan Sheth.
Guest: Larry Young, PhD
Host: Leslie P. Lundt, MD
Autism has garnered much attention in recent years. One of the most interesting areas of research is the exploration of oxytocin. Could it improve social interaction? Dr. Larry Young, the William P. Timmie Professor at the Center for Behavioral Neuroscience and the Department of Psychiatry at the Emory University School of Medicine, outlines his latest research with host Dr. Leslie Lundt.
Guest: Lorie Chaiten, JD
Host: Lauren Streicher, MD
For the past 25 years, the U.S. government has funded abstinence-only sex education in public schools. Still, 47 percent of high school students report having had sexual intercourse and 70 percent are sexually active by age 19. Lorie Chaiten, director of the Reproductive Rights Project for the Roger Baldwin Foundation of the ACLU of Illinois, talks with host Dr. Lauren Streicher about the implications for young people's sexual health when they are denied access to complete and accurate science-based information.
Guest: Mark Boucek, MD
Host: Mark Nolan Hill, MD
For years, we have performed pediatric heart transplants following the declaration of brain death in donors. To this point, those who die of cardiovascular complications have not been considered for heart donorship. How are advances in this area forcing us to reconsider the prospect of a heart transplant after cardiocirculatory death? Host Dr. Mark Nolan Hill considers the potential ramifications of this fascinating investigation with Dr. Mark Boucek, director of pediatric cardiovascular services at Joe DiMaggio Children's Hospital in Hollywood, Florida, and the lead author of research published in the New England Journal of Medicine on three cases of pediatric heart transplantation after cardiocirculatory death. Does this successful restarting of the heart in transplant recipients suggest that the donor's heart stoppage was not irreversible?
Guest: B. Rick Mayes, PhD
Host: Leslie P. Lundt, MD
Attention Deficit Hyperactivity Disorder (ADHD) holds the distinction of being the most extensively studied pediatric psychiatric disorder and one of the most controversial. Does the response from the public and from healthcare institutions impact our diagnosis and treatment of patients with ADHD? Dr. Rick Mayes, associate professor of public policy in the department of political science at the University of Richmond in Virginia, and a faculty research fellow at the Petris Center on Healthcare Markets and Consumer Welfare at the University of California, Berkeley, joins host Dr. Leslie Lundt to discuss how one community has improved care for their children with ADHD.
Host: Lisa Mazzullo, MD
Guest: Sharmila Makhija, MD
Since the Gardasil vaccination has only been administered to young girls and teens since 2006, there are still questions concerning who should get the vaccine and under what circumstances., and the effectiveness of the vaccine if not taken according to suggested protocol. Dr. Sharmila Makhija, director and associate professor of gynecologic oncology at the University of Alabama, tackles with host Dr. Lisa Mazzullo who should receive the vaccine. They also discuss whether or not it's beneficial for patients to be typed and tested for HPV before receiving the vaccinations, and what happens if a patient becomes pregnant while receiving the vaccine.
Guest: Armand Antommaria, MD, PhD
Host: Maurice Pickard, MD
Donation of the heart after asystole leads to questions about the point at which death is irreversible. Dr. Armand Antommaria, assistant professor in the division of pediatric inpatient medicine and an adjunct assistant professor in the division of medical ethics and humanities at the University of Utah School of Medicine, discusses the ways that pediatric cardiac transplant surgery may be pushing controversial organ-retrieval strategy beyond acceptable legal, moral, and ethical boundaries. Hosted by Dr. Maurice Pickard.
Host: Leslie P. Lundt, MD
Guest: Roger McIntyre, MD
It is reported that up to a fifth of bipolar disorder patients will commit suicide, yet there are few studies looking at clinical risk factors in this population. What is the latest research? Host Dr. Leslie Lundt welcomes Dr. Roger McIntyre, associate professor of psychiatry and pharmacology at the University of Toronto School of Medicine, to discuss his latest research investigating childhood abuse with adult bipolar suicide rates.
Guest: Lori Feldman-Winter, MD, MPH
Host: Jennifer Shu, MD, FAAP
Despite ambitious recommendations that new mothers breastfeed their infants for at least one year after birth, very few mothers meet this objective. Knowing there are barriers to breastfeeding--social, economic, and beyond--how can we help mothers get past these difficulties, where possible? Further, how can we allay the guilt many mothers feel when they're unable to breastfeed? For answers, host Dr. Jennifer Shu talks with Dr. Lori Feldman-Winter, associate professor of pediatrics at the University of Medicine and Dentistry of New Jersey, division head of adolescent medicine at Cooper University Hospital in Camden, N.J., and an Executive Committee member of the American Academy of Pediatrics section on breastfeeding.
Guest: Gregory Zimet, PhD
Host: Leslie P. Lundt, MD
Vaccines seem to always provoke controversy. Perhaps none so much as the HPV vaccine. Dr. Gregory D. Zimet, professor of pediatrics and clinical psychology at Indiana University School of Medicine, joins host Dr. Leslie Lundt to discuss the obstacles that may interfere with widespread acceptance of the HPV vaccine.
Guest: Cynthia Wong, MD
Host: Lisa Mazzullo, MD
Epidural anesthesia has changed dramatically since its introduction to the obstetric arena in the early 1970s. Now we have various types of epidurals we can administer during labor. One of the major obstacles for anesthesiologists is determining how women perceive pain during labor and how to administer the proper dosage of pain medication. Dr. Cynthia Wong, associate professor of anesthesiology at Northwestern University's Feinberg School of Medicine, joins host Dr. Lisa Mazzullo to discuss these issues, and her recent study that looks at the rate of Cesarean deliveries when epidural anesthesia is administered at different times during labor.
Guest: Sharmila Makhija, MD
Host: Lauren Streicher, MD
We are finding the highest prevalence of human papillomavirus (HPV) among women in their early 20s, but the FDA now recommends that an HPV vaccine be administered to women up to the age of 45. Why? Because recent research tells us that the at-risk population may be larger than we think. Dr. Sharmila Makhija, associate professor of gynecologic oncology at Emory University School of Medicine, weighs the pros and cons of this new recommendation with host Dr. Lauren Streicher.
Guest: Jamie Hutchison, MD
Host: Mark Nolan Hill, MD
A young patient is brought into the emergency department having suffered a traumatic brain injury. Hypothermia may be considered as part of the treatment regimen. If so, how soon after the injury should treatment begin, and how long should treatment last? Dr. Jamie Hutchison, associate professor of critical care medicine and pediatrics at the University of Toronto, and research director of critical care medicine at the Hospital for Sick Children in Toronto, explains the mechanism used for cooling and examines potential links between data on hypothermia treatment for adults and similar therapy for children. Dr. Mark Nolan Hill hosts.
Guest: Robert C. Fifer, PhD
Host: Gary Kohn, MD
Dr. Robert C. Fifer, associate professor and director of audiology and speech-language pathology at Mailman Center for Child Development, in the department of pediatrics at University of Miami School of Medicine, talks with host Dr. Bruce Bloom about what physicians need to know about speech and language development. What are other likely causes of slow development? When should chronic otitus media be a concern?
Guest: Raymond Scalettar, MD
Host: Bruce Japsen
So just how can the medical community prevent and reduce underage drinking? Is it even a doctor's responsibility? Dr. Raymond Scalettar, a former Chairman of the American Medical Association and an adviser to the Distilled Spirits Council, tells the Chicago Tribune's Bruce Japsen about what physicians may encounter and how they can help in dealing with adolescents with drinking problems.
Guest: Laurie Edwards
Host: Leslie P. Lundt, MD
Better technology and treatments mean that people with serious childhood illnesses such as cystic fibrosis and type one diabetes are reaching adulthood in unprecedented numbers. That means they are also struggling with college, relationships, fertility and employment. Laurie Edwards, a health journalist and author of Life Disrupted, joins host Dr. Leslie Lundt to discuss these issues.
Guest: Andrea Asnes, MD, MSW
Host: Cathleen Margolin, PhD
How can clinicians be prepared during a difficult pediatric encounter to create a favorable outcome? Dr. Andrea Asnes, assistant professor of pediatrics at the Yale University School of Medicine, talks with host Dr. Cathleen Margolin about how to handle difficult clinical encounters.