Crystallise is your weekly science fix! Join us as we talk about all things sciencey - from notable scientists who were forgotten from the history books, to the controversial CRISPR babies, and the development of synthetic blood. We promise you'll soon be just as obsessed with science as we are!
This week on Crystallise: Rosie tells us about a clinical trial where sight was restored to a blind man using light-sensing proteins from algae! Ash discusses how the face markings of peregrine falcons act like sunglasses, helping them to hunt in sunny climates.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
This week on Crystallise, Ash discusses analysing the DNA of ancient poo to discover how our gut microbiome has changed over the millennia. Rosie shares some brand new research where gene editing was used to lower cholesterol - potentially permanently - in primates, and could soon be available for humans.
Episode Sources.
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
This week on Crystallise: Rosie shares some new research that may take us a step closer to a cure for Alzheimer's disease. Ash discusses the release of genetically modified mosquitos in the Florida Keys in an attempt to curb the spread of infectious diseases.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
This week on Crystallise: Ash discusses some incredible new research that extracted DNA from cave soil to give us an insight into how Neanderthals lived over 100,000 years ago, and Rosie explores the science and ethics behind creating human-monkey chimeric embryos.
Episode sources:
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Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
Why do humans enjoy eating spicy food? This week, Rosie explores the psychology behind why we choose to eat food with chillies in it, even when it can be physically painful, and the possible health benefits of adding more spice to your life. In our SNPit, Ash discusses a study investigating how humans perceive emotions in screams.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
How many senses do you think you have? This week, Ash takes us on a tour of the senses, from those you know to those you might never have even known existed. In our SNP, Rosie shares the story of a woman who urinates alcohol.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
Honey is often said to have healing powers, but how much of that is true, and how much a myth? In this episode, Rosie looks into the effects of honey on healing and hay fever, and why eating too much of some types of honey might be a bad thing. In our SNPit, Ash discusses some new research showing that, like humans, octopuses might be having dreams.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
The placebo effect is a powerful phenomenon where non-active treatments result in an improvement of symptoms, but how does it work? In this week's episode, Ash explains some of the reasons behind this effect, and how our brains can be tricked into thinking a treatment is working.
In the SNPit, Rosie discusses how the 18-year-old murder conviction of Kathleen Folbigg may have just been overturned by the power of whole-genome sequencing.
Episode Sources.
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
Are we spending too much time looking at screens? In this episode, Rose investigates the potential negative health effects of blue light—from poor sleep, to macular degeneration, and even premature aging—and what we can do to avoid it. In our SNPit, Ash discusses a new study where scientists have created tiny crying tear glands in a dish.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
Do you look after your personal flora? Doing so might be crucial to living a healthy life! In this episode, Ash explores the human gut microbiome—what it is, what it does for us, and how to take care of it. In our SNPit, Rosie discusses a recent study that combined biology and physics to explain the mystery behind how egg cells get so large.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com).
Licensed under Creative Commons: By Attribution 3.0 License.
http://creativecommons.org/licenses/by/3.0/.
Why do we dream? And does eating cheese before sleeping make your dreams more vivid? In this week's episode, Rosie answers these questions and more as she delves into the science of dreaming. In our SNPit, Ash celebrates Brazil's first-ever home-built satellite, Amazonia-1, which was launched last week to keep an eye on deforestation in the Amazon rainforest.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Does drinking coffee make you live longer? In this weeks episode, Ash discusses the positive (and negative) health effects of coffee. For our SNPit—some new research using Neanderthal mini-brains to investigate how they were different from modern humans.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Conspiracy theories have thrived during the COVID-19 pandemic, but why do people believe in them? In this week's episode, Rosie discusses the psychology behind belief in conspiracies, mistrust of science, and how to combat "fake news". In our SNPit, Ash tells us about an incredible new technology that uses the heat of your body to charge batteries.
Episode Sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Henrietta Lacks' cells can be found in thousands of labs all over the world, but she never gave consent for that to happen. In this week's episode, Ash discusses the contributions Henrietta's cells have made to science, and whether we should still be using them at all. In our SNPit, Rosie shares some peculiar research about how the presence of parasitic worms may slow down aging.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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How does hormonal birth control affect your body? In this week's episode, we discuss the effects of hormonal birth control on your brain, your blood, and your weight, and some of the possible alternatives. For our SNPit, Ash explores some new research that could be a solution for the global food waste problem.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Advertised to help with anything from wrinkles to arthritic pain, collagen is the protein of the moment, but do collagen supplements actually do anything? In this weeks episode, Ash investigates collagen, and whether you should save or spend your money. In our SNPit, Rosie talks about how the future of data could be in bacteria.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Are we living through a mass extinction? This week, Rosie looks into mass extinction events and how they have shaped our planet. In our SNPit, Ash discusses the psychology of organised monkey crime.
Episode Sources:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Strange things can be found in lakes — animals that have turned to stone, or enormous hidden pockets of carbon dioxide. In this episode, Ash reveals the science behind three unusual lakes. In our SNPit, Rosie discusses some new research that shows how identical twins are not really identical.
Episode sources:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Why do we celebrate the new year on January 1st? In this episode, Rosie discusses how methods of developing calendars and marking time have evolved in different cultures. In our SNPit, Ash takes a look at whether mask-wearing during the COVID-19 pandemic could have a detrimental effect on children's ability to develop emotion-reading skills.
Episode sources:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Have you had a DNA test? This week, Ash tells us all about genetic testing, what it is, why you might want to do it, and how not to do it (i.e., why 23andMe is a bad idea). In our SNP, some new research into how both sparrows and humans use wormwood as preventative medicine.
Episode sources:
Angelina Jolie, Inherited Breast Cancer and the BRCA1 Gene
My Medical Choice - Angelina Jolie
The Limits of Ancestry DNA Tests, Explained
23andMe Is Terrifying, but Not for the Reasons the FDA Thinks
It's Not Just Humans. Sparrows Have Been Seen Using Preventative Medicine
Sparrows Use a Medicinal Herb to Defend Against Parasites and Increase Offspring Condition
We'll be taking a short break over the holidays, but in the meantime head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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dDid she sell seashells by the seashore? Probably not, but she did sell fossils. This week, Rosie takes a look at the life and legacy of pioneering paleontologist Mary Anning, who made a name for herself in the male-dominated geological spaces of the early 19th century through her incredible discoveries of Jurassic-age fossils. In our SNP, Ash discusses a new study describing how the 'stuff' we create now outweighs life on Earth.
For more on the topics discussed in this episode, have a look at these great articles:
She Sells Seashells and Mary Anning: Metafolklore with a Twist
Discovering Fossils: Geology of Lyme Regis
Mary Anning: The Unsung Hero of Fossil Discovery
Mary Anning: English Fossil Hunter and Anatomist
Human ‘Stuff’ Now Outweighs All Life on Earth
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Real science or pseudoscience? This week, Ash dives into the world of alternative medicine to talk all things homeopathy! In our SNP, Rosie tells us about an unusual approach to dingo conservation.
For more info on homeopathy, check out these articles!
Intrigued by tube man-dingo conservation? Have a read of this:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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92% of the world's population live with dangerous levels of air pollution - but what does this really mean? This week, Rosie delves into the past, present, and future of air pollution and what it's doing to our lungs and our brains. In our SNPit, Ash explains how humans have driven the evolution of a sought-after Chinese herbal medicine. Listen now!
To read more about air pollution, head to these links:
And if you're intrigued by the evolution of the Fritillaria delavayi herb, here's the research behind it:
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Do you know what's in your food? This week, we discuss the science behind genetically modified organisms - AKA GMOs - in agriculture; what they are, how they're made, and whether they should be a cause for concern.
In our SNPit - why are human brains so much larger than other primates? Rosie discusses some recent research that has attempted to figure this out by 'humanising' a monkey brain.
If you want to read more about GMO crops, have a look at these great articles:
What Are GMOs and GM Foods?
Genetically Modified Organisms (GMOs): Transgenic Crops and Recombinant DNA Technology
Science and History of GMOs and Other Food Modification Processes
The Truth about Genetically Modified Food
Freaked out by human-monkey hybrids? Check out the these for more info:
Uh-Oh, Scientists Used Human Genes to Make Monkey Brains Bigger
Human-Specific ARHGAP11B Increases Size and Folding of Primate Neocortex in the Fetal Marmoset
Head to our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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What are you scared of? This week, it's all about phobias: listen to find out why public speaking can be terrifying and why you have that weird dislike of pictures of holes. In our SNPit, Ash tells us how our brains deceive us into thinking prettier food is healthier.
To read more about phobias, check out these articles:
Why Do We Develop Certain Irrational Phobias?
Serotonin Synthesis and Reuptake in Social Anxiety Disorder
Unlocking The Psychology Of Snake And Spider Phobias
Common phobia you have never heard of: Fear of holes may stem from evolutionary survival response
Coffee bubble phobia may be deep-seated aversion to parasites
My Fear Of Spiders Was So Debilitating, I’m In Exposure Therapy. Here’s What It’s Like.
How Virtual Reality Can Help Overcome the Fear of Driving
For more about why prettier food is perceived as healthier, have a look at this:
Why Consumers Think Pretty Food Is Healthier
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week, Ash delves into the difficult topic of scientific racism, the eugenics movements of the early 20th century, and how it's still with us today. In our SNP, we discuss glowing, biofluorescent platypuses. As if they could get any weirder..
If you want to read more about eugenics, have a look at these articles:
For more on biofluorescence and glowing playtpuses, have a read of these:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Have you ever seen a ghost? This week it's a spooooky special, and Rosie takes a scientist's approach to explaining the paranormal. In our SNP, Ash gives everyone nightmares and explains how some people end up being declared dead while still alive.
To read more about ghosts, head to these links:
For more on the Lazarus Syndrome, check out this article:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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You might have heard of Theranos and Elizabeth Holmes, but do you know the full story of the biotech company that scammed billions of dollars from investors? This week, Ash dives into the facts behind the con. In our SNPit, Rosie makes it up to wasps, as they may be the answer to the growing antibiotic resistance crisis.
To read more about Theranos and Elizabeth Holmes, have a look at these articles:
For more info on wasp venom as an antibiotic, have a read of this:
Check out our Instagram or our website for more content, and if you liked this episode, support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Have you ever thought about living forever? This week, Rosie talks about aging: why we age, and how we might be able to slow it down or even reverse it. In our SNPit, Ash will tell you the best way to never miss the bus again.
To read more about aging, head to these links:
For more info on how to spend less time waiting for buses - have a look at this study:
Check out our Instagram or our website for more content, and support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week on Crystallise: Ash tells us the story of Marie Maynard Daly, the first African American woman to earn a PhD in chemistry in the United States, and just a few of her groundbreaking discoveries. For our SNPit, Rosie discusses some recent research into how virtually swapping bodies with a friend can lead to a loss of your sense of self, and even loss of memories.
To learn more about Marie Maynard Daly, head to these links:
To read more about how body swapping isn't quiiite the same in reality as it is in science fiction - have a look at these:
Check out our Instagram or our website for more content, and support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Why do women live longer than men? Well, it could be down to the Y chromosome. This week, we discuss the Y chromosome, how it seems to be mysteriously vanishing in older men, and the impacts this could be having on men’s health. In our SNPit, Ash tells us about how bird brains really aren’t that different from our own.
Check out these links for more info on the Y chromosome:
For more on birdbrains, head over here:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week on Crystallise: Ash explains the global decline in insect diversity, and the devastating impacts that it could have on our planet's ecosystem. In our SNPit, Rosie gives us another reason why Australia is out to get you - the venomous trees of Queensland.
To learn more about insect declines and the importance of protecting diversity, check out these links:
For more info about the stinging trees of Australia, have a look at these articles:
Check out our Instagram or our website for more content, and support the podcast by leaving a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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Could there be life on Venus? This week we discuss the new findings of possible microbial life on our next-door neighbour, and why we haven't found aliens elsewhere in our Universe. In our SNPit, Ash takes us inside the digestive tract and tells us about how we can check on our gut microbiome.
For more on the Fermi Paradox and the hunt for life on other planets, head to these links:
To read more about how we can check on the gut microbiome - have a look at this:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week, we take a look into the infamous CRISPR babies scandal, and discuss the ethics of gene editing. In our SNPit, Rosie tells us about how just like us, bats also use baby talk.
For more info on He Jianku, the CRISPR babies, and gene editing, head to these links:
Fascinated by bat baby talk? Check out these links:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week, we talk all about psychedelic drugs and how they could be extremely effective treatments for depression. In our SNPit, Ash tells us a story about ducks, locusts, and why you should be wary of what you read in the media.
For more on psychedelics and the studies discussed in this ep - check out these links:
To get the full story of the ducks and the locusts, head to these articles:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week, we venture deep underground and deep into space to learn all about volcanoes, on Earth and other planets! In our SNPit, learn about why your vision could be more similar to flies than you think.
Read more about volcanoes on Earth and in space at these links:
For more on flies and eyes have a look at these:
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week on Crystallise, Rosie tells us everything about clinical trials: what they are, what happens when they go wrong, and why the announcement of a Covid-19 vaccine in Russia outraged scientists worldwide. In our SNPit, Ash describes the unexpected effects of global coronavirus lockdowns on conservation efforts.
For more info on the topics discussed this week, check out the links below!
For more about the "anthropause" and the "Great Human Confinement Experiment" have a look at these:
Check out our Instagram for more content, and leave a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week, Ash tells us the story of Rosalind Franklin - a pioneer of X-ray crystallography and a crucial contributor to the discovery of the structure of DNA. In our SNPit, how metal-"breathing" bacteria could change electronics and help clean nuclear waste.
To read more about Rosalind Franklins discoveries, have a look at these links:
For more info from our SNPit, head here!
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Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week on Crystallise: Rosie tells us about the history of smallpox, and some new ancient Viking DNA research that sheds light on it's mysterious origins. In our SNPit, how to diagnose cancerous dinosaurs!
Read more about smallpox here:
Interested in diagnosing dinosaurs? Check out these articles!
Head to our Instagram for more content and leave a review wherever you listen!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week: Ash delves into to science behind fad diets and Rosie tells us why you we should be removing the “guilty” from “guilty pleasure”.
For more about the paleo and keto diets, have a look at the links below:
Take a look at the study behind guilty pleasures here:
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
This week, we learn about Esther Lederberg - another overlooked female scientist who helped to lay the groundwork of modern molecular biology. In our SNPit, Ash tells us about how city planners are responsible for your bad hayfever.
Read more about Esther Lederberg and bacteriophages at the links below:
Want to learn more about male trees, pollen, and hayfever? Check out these links:
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
This week, Ash tells us about a mysterious flesh-eating bacteria that’s appeared near Melbourne, and the disease it causes – Buruli ulcer. In our SNPit, we talk about spider silk, and how it could be the material of the future.
Read more about Buruli Ulcer at the links below:
Interested in reading more about spider silk? Check out these links!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
This week, Rosie introduces us to the weird world of cryptozoology, and we learn a little bit of the science behind the pseudoscience. For our SNPit, Ash tells the story of Alfred Russel Wallace, Edwin Rist, and the Great Feather Heist. Listen now!
For more info on the Cryptids we discussed in this episode, head to the links below:
More about Alfred Russel Wallace and the Great Feather Heist below:
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
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This week Ash talks about the history of plastics - from Celluloid to Tupperware - and how they were once considered the sustainable solution in our In Focus segment. In our SNPit, Rosie tells us about a new plan that could prevent the next pandemic.
Read more about the history of plastic and biodegradable alternatives below:
More about the Global Immunological Observatory below:
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
Have you donated blood? Less than 5% of Australians donate blood annually, but a donation can be lifesaving. This week, Rosie discusses the work being done by researchers around the world to try and create blood without the need for donors. In our SNPit, Ash introduces us to the weird and wonderful world of lab-produced milk, and how it could change the future of farming.
Read more about blood transfusions and how how scientists are tackling limited blood availability at the links below:
Interested in lab grown milk? More information below!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
You’ve probably seen it all over Instagram, you might have been sucked into it yourself – people are crazy for indoor plants! But why is it such as obsession? Ash (a self-confessed plant addict) goes in focus this week on a few studies which might help explain it.
In our SNPit, Rosie takes us through some recent research investigating how bees can change the seasonal flowering of plants.
Read more about why you're obsessed with plants in the links below:
Interested in bees? See below for more info on how they influence plants, and how you can help save the bees!
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/
This week, Rosie goes in focus to tell the story of Lise Meitner - a nuclear physicist who was integral to the discovery of nuclear fission - and we discuss the challenges faced by women in science. Ash continues the nuclear theme with her SNPit about the naming of medical imaging.
For more about Lise Meitner and the discovery of nuclear fission check out:
Want to learn more about MRI? Head to these links:
Music:
AhDah Kevin MacLeod (incompetech.com)
Licensed under Creative Commons: By Attribution 3.0 License
http://creativecommons.org/licenses/by/3.0/