Down the Ocular: Recent Episodes

Roche Diagnostics Medical and Scientific Affairs Team

Welcome to Down the Ocular, a podcast looking down the ocular into diagnostic testing. Here, your Roche Medical and Scientific Affairs team will talk about tests, validation, and the guidelines that inform diagnostic testing in the clinical setting.

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In this episode, Drs. Ray Hein, Chris McGowin, and Steven Cagas discuss SARS-CoV-2 screening, surveillance, and specimen pooling. How do we envision the testing landscape for SARS-CoV-2 looking in the near future? Drs. Hein, McGowin, and Cagas will give us their perspectives. This conversation was recorded on April 15, 2021. The information presented is current as of that date.

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In this episode, Drs. Jamie Phillips, Laura Parnas, and Tabari Baker discuss the fact versus fiction of the COVID-19 vaccines. We learn which of the myths about the COVID-19 vaccines are true, and which are false. The experts, Dr. Phillips and Dr. Parnas, provide clear guidance.  This conversation was recorded on March 31, 2021.  The information presented is current as of that date.

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In this episode, our colleagues Drs. Jamie Phillips, Allison McMullen, and Ray Hein educate us on SARS-CoV-2. Here, we learn about the SARS-CoV-2 variants, and their potential impact on molecular diagnostic testing.

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In this episode, Dr. Lupe Manriquez and Dr. Bharathi Vennapusa discuss CAP/ASCO Estrogen Receptor (ER)/Progesterone Receptor (PgR) guideline update from 2020 and how it pertains to the Roche ER/PgR assays.

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In this episode, Drs. Ed Baker, Linda Ahn, Bharathi Vennapusa, and Tabari Baker will frame the clinical utility of the CINtec PLUS Cytology assay by discussing the 2019 ASCCP Risk Based Management Guidelines.

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In this episode, Roche Tissue Diagnostics Medical and Scientific Affairs colleagues Bharathi Vennapusa, MD and Tabari Baker, PhD discuss the 2018 CAP/ASCO HER2 Guidelines. Drs. Vennapusa and Baker provide an overview of the guidelines, the recent changes, and how the Roche HER2 assays fit within the guidelines.

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This episode is part 2 in a series on the PD-L1 (SP142) assay in non small cell lung cancer.  In this episode, Roche Tissue Diagnostics Medical and Scientific Affairs colleagues Bharathi Vennapusa, MD and Tabari Baker, PhD discuss the PD-L1 (SP142) assay in non-small cell lung cancer. Drs. Vennapusa and Baker provide technical details on the PD-L1 (SP142) assay.

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In this episode, Roche Tissue Diagnostics Medical and Scientific Affairs colleagues Bharathi Vennapusa, MD and Tabari Baker, PhD discuss the PD-L1 (SP142) assay in non-small cell lung cancer.  Drs. Vennapusa and Baker provide an overview of the assay, the algorithm, and the data that supports the assay approval.  If you have questions about PD-L1 (SP142), Drs. Vennapusa and Baker have answers. 

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This episode focuses on the NTRK fusions; their detection, the testing methodologies used, and their role in solid tumors.  Dr. Bharathi Vennapusa answers your questions about NTRK here! 

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In this episode, Roche Tissue Diagnostics Medical and Scientific Affairs colleagues Bharathi Vennapusa, MD and Tabari Baker, PhD discuss the use of digital pathology devices during the COVID-19 pandemic.  What guidance has the FDA given?  What guidance has CMS given?  What are the recommendations for operating digital pathology devices and reading digital pathology images during this time?  Bharathi and Tabari will guide the conversation and provide insights.