Tox in Ten: Recent Episodes

Elizabeth Moore, Gillian Beauchamp et. al

Welcome to Tox in Ten! We are dedicated to bringing you evidence-based medical toxicology core content and trending topics in easily digestible bites

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In this episode Dr. Gillian Beauchamp sits down with Dr. Andrew Stolbach to discuss the mechanishm of action, toxicity and management of checkpoint inhibitors (immunotherapeutic agents used in the treatment of cancer).

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In this episode Dr. Gillian Beauchamp sits down with Dr. Joshua Trebach to discuss the benefits and drawbacks of utilizing social media to increase awareness and promote medical toxicology.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Filza Hussain to discuss transplant organ allocation in patients who have organ failure secondary to a suicide attempt.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Matthew Salzman discusses the complications associated with the use of illicit fentanyl containing xylazine from wounds to withdrawal.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Alan Wolfe to discuss the possible clinical effects of POPs (Persistent Organic Pollutants) and PFAS (Per and polyfluoroalkyl substances).

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In this episode Dr. Gillian Beauchamp sits down with Dr. Travis Olives to discuss gap junctions and cardiac effects of bupropion toxicity.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Stephanie Weiss to discuss HERG channel blockade, QTc prolongation and cardiotoxicity.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Meghan Spyres to discuss the evolution of antivenom treatment of North American Pit Viper envenomation with specific discussion of the differences between Fab (CroFab) and F(ab)2 (ANAVIP) antivenom.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Christian Tomaszewski to discuss risk factors for delayed cardiomyopathy and mortality after carbon monoxide exposure.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Alex Manini to discuss single nucleotide polymorphisms (SNPs) of the Mu receptor and how they may relate to overdose severity of opioid overdose.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Fiona Garlich to discuss mechanisms and clinical presentations of aconitine, veratrum alkaloid and grayanotoxin cardiotoxicity. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Robert Haley to discuss Gulf War Illness and what caused over 100,000 people to become ill during and after the Gulf War. Dr. Haley describes the gene-environment interaction between PON-1 polymorphism and exposure to sarin gas. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Spencer Greene to discuss his recent case series of antimuscarninic delirium treated with rivastigmine in the setting of physostigmine shortages. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Tricia Wright to discuss risk factors leading to methamphetamine use disorder, associated complications in pregnancy and management of substance use disorder in pregnant and postpartum patients. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Tricia Wright to discuss the known and theoretical risks of cannabis use during pregnancy and lactation.  

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In this episode Dr. Gillian Beauchamp sits down with Dr. Mishka Terplan to discuss stigma, discrimination and prejudice in relation to substance use in pregnancy. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Lori Devlin to discuss  Neonatal Abstinence Syndrome (NAS), Neonatal Opioid Withdrawal Syndrome (NOWS) and the treatment of NOWS. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Kurt Kleinschmidt to discuss the differences between dependence, addiction, and substance use disorder and how it relates to medication associated treatment (MAT). 

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In this episode Dr. Gillian Beuachamp sits down with Assistant Chief of Police Matthew Myers to discuss the Drug Recognition Evaluation (DRE) and the Drug Influence Evaluation (DRE) assessments.

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In this episode Dr. Gillian Beauchamp sits down with Patrick Harding to discuss anterograde and retrograde ethanol calculations and how they are used in forensic toxicology.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Laura Tormoehlen  to discuss the nuances of brain death declaration in the toxicology patient

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In this episode Dr. Gillian Beauchamp sits down with Dr. Andrew Monte to discuss common nomenclature used in pharmacogenetics and pharmacogenetic factors that impact patient care in the ICU. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Brenna Farmer to discuss the process of gaining approval to use medications past their original expiration dates. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Donna Seger to discuss the clinical advantages of having a medical toxicologist at the bedside

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In this episode,  Dr. Gillian Beauchamp sits down with Dr. Susanna Byram to discuss the use of VV and VA ECMO and other Mechanical Circulatory Support Devices in poisoned patients. 

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In this episode Dr. Gillan Beauchamp sits down with Dr. Joshua King to discuss dosing adjustments of common antidotes and medications in patients undergoing HD and CCRT.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Zane Horowitz to discuss the challenges and strategies to provide toxicology care in remote locations.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Zane Horowitz to discuss the toxicity and myths of the Amanita Muscaria mushroom

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In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Chary to discuss the role of artificial intelligence in medical toxicology.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Zane Horowitz to discuss Amanita mushroom toxicity in the Northwest United States.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Ayrn O’Connor to discuss the clinical presentation and treatment of methamphetamine toxicity in children

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In this episode Dr. Gillian Beauchamp sits down with Dr. Milky Kohno, PhD to discuss naltrexone as a treatment strategy for methamphetamine use disorder. 

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In this episode Dr. Gillian Beauchamp sits down with  Shaun Hopkins to discuss syringe services programs (SSPs) and overdose prevention sites (OPS).

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In this episode Dr. Gillian Beauchamp sits down with Dr. Bryan Judge to discuss the process of becoming a medical consulting expert. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Michael Lynch to discuss refractory ethanol withdrawal and the role of ketamine. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Daniel Sessions to discuss the potential toxicity of classic cocktails. 

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In this episode Dr. Gillian Beauchamp Sits down with Dr. Stephanie Weiss to discuss the chronic effects of methamphetamine and other stimulants such as cocaine on the heart. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Kennon Heard to discuss protein adducts in diagnosing APAP overdose 

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In this episode Dr. Gillian Beauchamp, MD sits down with Dr. Matthew Fedoruk, PHD to discuss the inclusion of cannabinoids on the World Anti-Doping Agency’s banned substances list.

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In this episode Dr. Gillian Beauchamp sits down with Dr. Jeffery Brent to discuss the use of fomepizole in acetaminophen toxicity

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In this episode Dr. Gillian Beauchamp sits down with Dr. Will Heise to discuss the potential benefits of implementing pharmacogenomic testing in clinical inpatient and outpatient settings. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. George Chiampas to discuss the logistics of drug testing from the perspective of a team physician and medical director of large sporting events

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In this episode Dr. Gillian Beauchamp sits down with Dr. Daniel Sessions to discuss the use and testing of performance enhancing agents in the military

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In this episode Dr. Gillian Beauchamp sits down with Dr. Kavita Babu to discuss incorporating medico-legal consultation into your medical toxicology practice. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Monica Schoch-Spana to discuss to the Panic Myth and bystander reactions to chemical incidents and other disasters.

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In this episode Dr. Gillian Beauchamp sits down with Peter Chai to discuss two areas of his research. Access to illicit drugs and antidotes like naloxone on the dark web and the bioequivalence of digital pills used to monitor patient adherence to medication 

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In this Episode Dr. Gillian Beauchamp sits down with Dr. Fiona Garlich to discuss current trends in e-cigarettes/vaping and review recent clinical cases of vaping associated lung injury. 

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In this episode Dr. Gillian Beauchamp sits down with Dr. Marilyn Huestis to recap her talk The Great US Cannabis Experiment: Short and Long Term Consequences. 

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In this episode Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Medical Toxicologist Dr. Vik Bebarta to discuss new developments in identifying and treating cyanide toxicity. 

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In this episode Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Medical Toxicologist Dr. Lewis Nelson to discuss dosing, use and potential pitfalls of naloxone for  acute opioid overdose

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In this episode Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Dr. Timothy Wiegand for a discussion of the history, benefits and potential complications of buprenorphine therapy for opioid use disorder. 

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In this episode Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Medical Toxicologist Dr. Timothy Wiegand for a discussion on the history of methadone and it's potential toxicity.

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In this episode of Tox in Ten ACMT Highlights, Dr. Gillian Beauchamp sits down with Chief Medical Examiner of Connecticut, Dr. James Gill. Join their discussion on the Medical Examiner's perspective on opioid related deaths. 

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In this episode of Tox in Ten ACMT Highlights, co-host Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Medical Toxicologist Dr. Jeanmarie Perrone. Join their discussion on the opioid epidemic, how we got here, and strategies moving forward. 

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In this episode of Tox in Ten ACMT Highlights, co-host Dr. Gillian Beauchamp sits down with Emergency Medicine Physician and Medical Toxicologist Dr. Spencer Greene to discuss the use of Flumazenil and Physostigmine. 

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In this Episode of Tox in Ten ACMT Highlights, co-host Dr. Gillian Beauchamp sits down with pediatrician and medical toxicologist Dr. Diane Calello to discuss IV lipid emulsion therapy in poisoned patient. 

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In this Episode of Tox in Ten ACMT Highlights, co-host Dr. Gillian Beauchamp sits down with nephrologist and medical toxicologist Dr. Josh King to discuss the use of renal replacement therapy in poisoned patients. 

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In the very first episode of Tox in Ten, host Elissa Moore (@ElissaMoore3) explores the evidence and recommendations surrounding intubation of the salicylate toxic patient.

Follow Tox in Ten and Tox in Ten: ACMT Highlights @ToxinTen and on our website: www.toxinten.com

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In this episode of Tox in Ten ACMT Highlights, co-host Dr. Gillian Beauchamp sits down with toxicologist Dr. Rob Hendrickson to discuss the nuances of naloxone dosing in various clinical scenarios