Irritable Bowel Syndrome News -- ScienceDaily: Recent Episodes
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In a comparative pilot study, the Mediterranean diet and the low FODMAP diet both provided relief for patients with IBS.
Children who frequently miss school because of abdominal complaints are far more likely to be suffering from chronic disorders such as irritable bowel syndrome than diseases that can be detected with medical tests, new research has found.
Study participants who went on an IgG-based elimination diet--based on a novel blood test--experienced less abdominal pain than those on a sham diet.
Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists may alleviate IBS symptoms by acting directly on the central nervous system. Using a novel stress-induced mouse model, they found these drugs reduce abdominal pain and regulate bowel movements. This research suggests a promising approach to treating IBS by targeting stress as a contributing factor.
Researchers found that vegetarians who consumed PBMAs had a 42% increased risk of depression compared to vegetarians who refrained from PBMAs.
A research team has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain. This groundbreaking innovation offers a safe, non-opioid-based solution for conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), which affect millions of people worldwide.
Researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions.
An international study has found that genetic variations in human carbohydrate-active enzymes may affect how people with irritable bowel syndrome (IBS) respond to a carbohydrate-reduced diet.
Symptoms for patients with the gastrointestinal disease IBS improved as much by eating less sugar and starch as for those who followed FODMAP -- the diet currently recommended to patients. The results also show that weight loss is greater and sugar cravings are reduced among those who follow the starch and sucrose-reduced diet.
Researchers examined the clinical, lifestyle, and multi-omic data of more than 1,400 healthy adults. How often people poop, they found, can have a large influence on one's physiology and health.
Dietary treatment is more effective than medications in irritable bowel syndrome (IBS). With dietary adjustments, more than seven out of ten patients had significantly reduced symptoms.
In the first comprehensive evidence-based guideline on the use of fecal microbiota-based therapies for gastrointestinal disease, the American Gastroenterological Association recommends fecal microbiota transplant (FMT) for most patients with recurrent Clostridioides difficile (C. diff) infection. FMT therapies are not recommended as a treatment for inflammatory bowel diseases (IBD) or irritable bowel syndrome (IBS).
Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.
Researchers have found a significant relationship between the risks for endometriosis and common gastrointestinal disorders such as IBS, peptic ulcer disease (PUD) and gastro-oesophageal reflux disease (GORD). Sufferers can find it difficult to distinguish the source of their pain leading to confusion or misdiagnosis and years of delay in treatment during which time the endometriosis can progress to more severe disease -- endometriosis should be considered as a possible cause if a woman presents to her GP with abdominal pain and gastrointestinal symptoms.
Amitriptyline can improve symptoms of irritable bowel syndrome in patients seen in GP surgeries, new research has found. The cheap and widely available prescription drug, which is commonly used at low doses for a range of health concerns, has been found to improve irritable bowel syndrome (IBS) symptoms too, according to the results of the ATLANTIS trial. The results showed that patients taking amitriptyline were almost twice as likely to report an overall improvement in symptoms as those taking a placebo.
Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.
People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.
A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.
A new theory suggests irritable bowel syndrome (IBS), the most common gastrointestinal disorder, may be caused by gravity. An expert explains that IBS -- and many other conditions -- could result from the body's inability to manage gravity.
Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study.
Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive.
The culprit is what has now been named Klebsiella aerogenes, the McMaster-Queen (MQ) strain, identified in up to 25 per cent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts.
Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study does not show a relationship between high intake of gluten and increased IBS symptoms. The researchers did find that a certain type of carbohydrate called 'fodmaps' can aggravate intestinal problems, however, the overall results indicate that they also have less influence than previously thought.
For patients who have irritable bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.
In a randomized clinical trial, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill -- referred to as an honest or open-label placebo -- reported clinically meaningful improvements in their IBS symptoms.
Researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study was carried out in mice and humans.
Preclinical studies find that an innovative bilayered capsule can overcome current challenges for delivering drugs to the colon. The findings suggest a new solution for relieving abdominal pain associated with IBS-C.
Researchers have detected a connection between Brachyspira, a genus of bacteria in the intestines, and IBS -- especially the form that causes diarrhea. Although the discovery needs confirmation in larger studies, there is hope that it might lead to new remedies for many people with irritable bowel syndrome.
Almost one in five patients with COVID-19 may only show gastrointestinal symptoms, according to a review of academic studies. The findings of the review suggest abdominal radiologists need to remain vigilant during the pandemic while imaging patients.
Molecules from the venom of one of the world's largest spiders could help researchers tailor pain blockers for people with irritable bowel syndrome (IBS).
Researchers have found that combining a Western-style high-fat diet with antibiotic use significantly increases the risk of developing pre- inflammatory bowel disease. This combination shuts down the mitochondria in cells of the colon lining, leading to gut inflammation. Mesalazine can help restart the mitochondria and treat pre-IBD condition.
Researchers have conducted a trial involving 144 patients to compare the effectiveness of a multidisciplinary clinic - involving gastroenterologists, dieticians, psychiatrists and physiotherapists - with usual gastroenterology specialist-only care.
Patients with COVID-19 can have bowel abnormalities, including ischemia, according to a new study.
Foods, such as French fries, cheese, cookies, soda, and sports and energy drinks, are commonly found in the diets of United States adults with inflammatory bowel disease, according to a new study.
Adults with irritable bowel syndrome experienced fewer gastrointestinal symptoms after they participated in a mindfulness program meant to reduce stress.
A green, single-celled organism called Chlamydomonas reinhardtii has served as a model species for topics spanning algae-based biofuels to plant evolution. While algae have been used as dietary nutraceuticals that provide beneficial oils, vitamins, proteins, carbohydrates and antioxidants, the benefits of consuming C. reinhardtii were previously unexplored. Researchers have now completed the first study in humans demonstrating that C. reinhardtii helps improve human gastrointestinal problems related to irritable bowel syndrome, including diarrhea, gas and bloating.
For some unlucky people, a bout of intestinal distress like traveler's diarrhea leads to irritable bowel syndrome. Recent discoveries have given scientists a better idea of how this happens, and potential leads for new treatments.
This is big news for irritable bowel syndrome (IBS) patients: 11% of the world's population suffers from IBS, but the fight against chronic pain has taken a major step forward with scientists identifying receptors in the nervous system which cause the condition in the hope of developing effective treatments.
New research has found that a diet low in fermented carbohydrates has improved certain gut symptoms and improved health-related quality of life for sufferers of inflammatory bowel disease (IBD).
Because researchers demonstrated for the first time that a strong association between obesity and chronic diarrhea is not driven by diet or physical activity, the findings could have important implications for how physicians might approach and treat symptoms of diarrhea in patients with obesity differently.
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder affecting 10 - 20 per cent of people. Abdominal pain, bloating and altered bowel habit significantly affect patient's quality of life and can force them to take days off work.
Scientists have identified new biomarkers for Irritable Bowel Syndrome (IBS) in urine, which could lead to better treatments and reduce the need for costly and invasive colonoscopy procedures currently used for diagnosis.
The more abnormalities in intestinal and brain function that IBS sufferers have, the more severe their symptoms of this functional bowel disorder, and the more adversely their everyday life is affected. This is shown by a study indicating that patients with IBS should get treatments for different abnormalities simultaneously, to improve both bowel function and signaling from the brain to the gut.
To improve the treatment of children with irritable bowel syndrome (IBS), investigators have developed a sophisticated way to analyze the microbial and metabolic contents of the gut. A report describes how a new battery of tests enables researchers to distinguish patients with IBS from healthy children and identifies correlations between certain microbes and metabolites with abdominal pain. With this information, doctors envision tailoring nutritional and targeted therapies that address a child's specific gastrointestinal problems.
Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder affecting 10 - 20 per cent of people. Abdominal pain, bloating and altered bowel habit significantly affect patients' quality of life and can force them to take days off work. New research has shown that Cognitive Behavioural Therapy (CBT) tailored specifically for IBS and delivered over the telephone or through an interactive website is more effective in relieving the symptoms of IBS than current standard care.
A study has revealed an insidious aspect of the gut protozoan Blastocystis, which is largely thought to be a harmless commensal organism. A Singaporean subtype of Blastocystis, ST7, caused the destruction of 'good' bacteria in the gut through activating reactive oxidative species. ST7 also caused damage to the gut epithelial lining. This discovery has implications for inflammatory bowel disease, irritable bowel syndrome, gastrointestinal cancers, and fecal microbiota transplantation.
Research indicates that cutting out specific foods can alleviate the gastrointestinal issues some people experience when they exercise, with over two-thirds of people involved in a new study reporting an improvement.
Immune cells in the bowel of people who suffer with celiac disease are permanently replaced by a new subset of cells that promote inflammation, suggests a new study.
Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer. This is the first report to show these men have higher than average PSA values and a significantly higher risk of potentially dangerous prostate cancer. They need to be screened more carefully for prostate cancer. About 1 million men have inflammatory bowel disease in the U.S., a common chronic condition that includes Crohn's disease and ulcerative colitis.
The small intestine is a hotbed of microbial activity and a target of probiotic treatments for diarrhea, inflammatory bowel disease and irritable bowel syndrome, among other conditions. To make it to the intestine, though, probiotics must first pass through the stomach, a hostile acidic environment that can kill these beneficial bacteria. Now, scientists report the development of a protective gel sphere that may offer probiotics a safer route.
A study has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome. Combining this data with data from an earlier microbiome study, the researchers now report they can predict whether or not someone has the disorder with a confidence of 84 percent.
Researchers have found that immune cells called macrophages can trigger smooth muscle contractions in the intestinal tract, independent of nerve cells.
Scientists have identified an early cause of intestinal inflammation, one of the first stages of inflammatory bowel disease and irritable bowel syndrome, which afflict around 11 percent of the world's population.
Investigators have for the first time identified a gas produced in gut that could improve the diagnosis and treatment of patients with two common intestinal illnesses -- small intestine bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS).
Utilizing newly adapted artificial intelligence, researchers have developed an acoustic belt that offers a new way to diagnose irritable bowel syndrome (IBS) by listening to the noises in a patient's gut/
In the largest federally funded non-drug clinical trial for irritable bowel syndrome (IBS), patients with the most severe and persistent symptoms achieved robust and sustained relief by learning to control symptoms with minimal clinician contact.
Little is still known about the exact causes of irritable bowel syndrome. An international team has provided initial clues about the organic triggers of the disease, which affects an estimated one out of six people.
New research links certain DNA variants to increased risk of irritable bowel syndrome (IBS) in women. The findings might help explain why IBS is more common in women than in men.
New research finds high prevalence of vitamin D deficiency in IBS patients -- regardless of their ethnicity
Patients with irritable bowel syndrome who follow individualized diets based on food sensitivity testing experience fewer symptoms, say researchers. Their study is among the first to provide scientific evidence for this medication-free approach to a debilitating condition.
The intestinal barrier of patients with the gastrointestinal disease IBS allows bacteria to pass more freely than in healthy people, according to a study. The study is the first to investigate IBS using living bacteria.
Gut bacteria play a key role in regulating abdominal pain and its associated changes in the brain and spinal cord, at least in mice, report scientists.
A specific type of irritable bowel syndrome is associated with exhaustion of the immune system in patients, researchers have discovered for the first time.
In the days following abdominal surgery, patients' intestinal contents pass more slowly or not at all. New research has now shown that this phenomenon -- known as post-operative ileus or bowel paralysis -- is not caused by the cells previously identified as the main players. Quite the opposite, in fact: the cells even help restore bowel function. The findings are very important for further research into post-operative patient treatment.
A review of published studies has found that people who exercise excessively may be prone to acute or chronic gut issues.
A new study is the first to show improved depression scores with a probiotic. It adds to the whole field of microbiota-gut-brain axis, providing evidence that bacteria affect behavior.
A new study of 483 patients with irritable bowel syndrome (IBS) revealed that many factors that contribute to patient satisfaction are beyond the doctor's control.
Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition.
Abnormal levels of specific gut bacteria are related to chronic fatigue syndrome/myalgic encephalomyelitis, or ME/CFS, in patients with and without concurrent irritable bowel syndrome, or IBS, scientists have discovered.
Health psychologists have begun treating gastrointestinal disorders that are strongly affected by stress, including irritable bowel syndrome (IBS), Crohn’s disease, functional heartburn, functional dyspepsia and ulcerative colitis.
The goal of a new study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice. Using fecal transplants, researchers transferred microbiota from IBS patients with or without anxiety into germ-free mice. The mice went on to develop changes both in intestinal function and behavior reminiscent of the donor IBS patients, compared to mice that were transplanted with microbiota from healthy individuals.
A one-off bowel screening test reduces the risk of developing bowel cancer by more than one third and could save thousands of lives, according to a study.
A research team is the first to uncover reasons why a specific type of immune cell acts very differently in females compared to males while under stress, resulting in women being more susceptible to certain diseases.
Changes to the microorganisms (microbiota) in the gastrointestinal (GI) tract may be a cause of irritable bowel syndrome (IBS), suggest scientists.
The type of psychotherapy used to treat the gastrointestinal disorder irritable bowel syndrome makes a difference in improving patients' daily functioning, new research has found.
Cruise ships, nursing homes, and daycare centers are common breeding grounds for norovirus, a contagious stomach bug that infects 685 million people around the world each year. Despite its prevalence, norovirus -- which has no specific treatment and is particularly dangerous in infants and the elderly -- has received surprisingly little attention from researchers. Viral shedding can occur for up to a few months in healthy individuals.
Irritable bowel syndrome (IBS) affects a large portion of the general population. New research coordinated by Karolinska Institutet now shows a link between defective sucrase-isomaltase gene variants and IBS.
Patients suffering from pain related to irritable bowel syndrome (IBS) may benefit from taking pregabalin, a neuro-pain inhibitor commonly used to treat fibromyalgia, a pilot study has found.
A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis.
New research indicates that in patients with irritable bowel syndrome (IBS) or indigestion, there is a distinct brain-to-gut pathway, where psychological symptoms begin first, and separately a distinct gut-to-brain pathway, where gut symptoms start first. In the study, higher levels of anxiety and depression were significant predictors of developing IBS or indigestion within 1 year.
Patients with irritable bowel syndrome (IBS) are often concerned that certain foods may trigger or worsen their symptoms, which can include abdominal pain, diarrhea, or constipation. In a new study, patients who ate rye bread that was low in so-called 'FODMAPs' (fermentable oligo- di- and mono-saccharides and polyols) experienced milder IBS symptoms than patients who ate normal rye bread.