Dermatology Snapshots: Recent Episodes
Dr Vanessa Pinder
Consultant Dermatologists Dr Jiyad and Dr Ferguson at St George's hospital, Tooting produce a monthly journal review newsletter, which just summarises clinically relevant studies, from various dermatology and general medical journals. There just never seems to be enough time to stay up to date with all the various journals and find publications that contain clinically relevant messages. This is the podcast version so that you can keep up to date whilst enjoying the delights of the Northern line or whilst driving to work in your Aston Martin. But perhaps not when cycling to work.
1) Semaglutide for weight loss in obese patients as an adjunctive treatment for HS: its impact on disease control and quality of life
2) Deep dive on IgA Vasculitis
3) Improved clinical effectiveness of adalimumab when initiated with clindamycin and rifampicin in HS
4) Does PRP treatment really work
5) Topical steroid withdrawal: a survey of UK dermatologists attitudes
6) MHRA update on labelling of topical steroids with warnings
7) Clinical outcomes and management of JAK inhibitor associated acne in patients with moderate to severe atopic dermatitis undergoing upadacitinib: a multicentre retrospective study
8) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) Comparison of topical permethrin 5% v benzyl benzoate 25% treatment in scabies a double blinded randomised controlled trial
2) Ask an expert: Dr Claire Fuller
3) The Art of communicating risk and benefit to promote shared decision making, informed by behavioural economic priniciples
4) Exploration of the optimal time to discontinue propranolol treatment in infantile haemangiomas: a propective study
5) Discontinuation of anti TNF treatment due to blood test abnormalities and cost effectiveness of alternative blood monitoring strategies
6) Acne keloidalis nuchae: and international multicentric review of 79 patients.
7) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) Factors associated with early onset androgenetic alopecia: a scoping review
2) Results of a treatment algorithm for generalised granuloma annulare
3) Post-inflammatory hyperpigmentation: A systematic review of treatment outcomes
4) Nice updates: difelikefalin and ritlecitinib
5) Anti-SS-A antibody is a potential predictor of severe SJS and TEN: a retrospective cohort study
6) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) Risk of paradoxical eczema in patient receiving Biologics for eczema
2) Surgical excision verses topical 5% 5 fluorouracil and PDT therapy in the treatment of Bowen’s disease
3) Using UV light in diagnosing scabies: Scabies sign via Wood’s light.
4) Bridging the gap in BASCULE syndrome. A retrospective cases series of a recently described clinical entity.
5) Natural language processing to automate a web-based model of care and modernize skin cancer MDT meetings
6) Staphylococcus aureus induced drug resistance in cancer T cells in Sezary syndrome
7) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) Report of the commission on human medicines isotretinoin implementation advisory expert working group
2) 2023 ACR/ EULAR antiphospholipid syndrome classification criteria
3) Adalimumab in conjunction with surgery compared with adalimumab monotherapy: a randomised control trial in a real world setting
4) Elevated risk of visceral malignant neoplasms in extramammary Paget Disease.
5) Clinical characteristics associated with musculoskeletal extracutaneous manifestations in pediatric and adult morphea: a prospective cohort study.
6) Exposure to biologic therapy before and during pregnancy in patients with psoriasis: systematic review and meta-analysis
7) Prognostic significance of incipient ulceration in primary cutaneous melanoma
8) Sclerema neonatorum
9) Intravascular large B cell lymphoma
10) Neoplasia risk in patients with Lynch syndrome treated with immune checkpoint blockade. Microwave energy devices for hyperhidrosis are associated with infections, neurologic symptoms and burns in a retrospective analysis of the Manufacturer and User Facility Device Experience Database 2013- 2022.
11) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) Real world implementation and outcomes of adalimumab therapeutic drug monitoring in psoriasis: a national specialised centre experience
2) Epidemiology and diagnostic classification of adults presenting with leukocytoclastic vasculitis: a multi-centre review of 440 patients
3) The implications of a Dermatopathologist’s report on melanoma diagnosis and treatment
4) Disabling pansclerotic morphea and STAT4
5) Trichodysplasia spinulosa: what is it?
6) The long term safety of topical corticosteroids in atopic dermatitis: a systematic review
7) Martha’s rule: what could the proposed rule mean for doctors?
8) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1) JAK inhibitors and the risk of malignancy: a meta-analysis across disease indications.
2) Prognostic factors for long-term aesthetic outcomes of infantile haemangioma treated with beta-blockers.
3) Topical Steroid Withdrawal. What do we know about this growing problem.
4) Is methotrexate safe for men with immune mediated inflammatory disease and an active desire to become a father? Results of a prospective cohort study (iFAME-MTX)
5) Prurigo pigmentosa: a multi institutional retrospective study
6) Sucidal behaviour in psychodermatology patients: identifying characteristics and a new model for referral.
7) Why Nigeria has declared skin lightening a health emergency
8) JRobert Oppenheimer and the social responsibility of science
9) Profiling UK injectable aesthetic practitioners: a national cohort analysis
10) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
In this issue:
- Spironolactone for acne - does it work?
- Paroxetine for erythema of rosacea
- Methotrexate monitoring schedules - should we rethink 3 monthly bloods?
- Long-term neurocognitive affects of propranolol
- NICE eczema update
- What’s Multinucleate Cell Angiohistiocytoma?
-
- more…
- Surgical delay for invasive melanoma - what's the impact?
- Subcutaneous fat necrosis of newborn
- Microsurgery for lymphoedema- is it safe?
- Facial atopic eczema and food allergy
- What's Yao Syndrome?
-
- More
- Dupilumab and eye disease - incidence and management
- Risk factors for progression from DLE to SLE
- Isotretinoin and IBD risk - what’s the risk?
- Outcomes of MELTUMP and SAMPUS
- Atrophic papulosis - features
- The case for digital minimalism
-
- More…
- Methotrexate- does it cause liver fibrosis?
- Bowen's disease- updated management guidelines
- Vitamin D for Toxic Erythema of Chemotherapy
- EPP- focusing on the presentation
- JAK inhibitors- what's the cardiac and VTE risk?
- Looking after our own...
Which second line treatment is best for scabies?
Can we stop Ustekinumab in responders?
Are bloods needed in FPHL?
What is mid-childhood acne?
Sentinel node biopsy in T1a melanoma, what does it add?
Skin signs in catastrophic antiphospholipid syndrome
1 Facial erythema in patients with atopic dermatitis treated with Dupilumab- a descriptive study of morphology and aetiology
2 The need for potassium monitoring in women on spironolactone for dermatologic conditions
3 Tacrolimus “swish and spit” for complex aphthosis: outcomes in 21 patients
4 Increasing prevalence of ANA in the US
5 Cutaneous polyarteritis nodosa diagnosis and treatment: retrospective case series
6 Cutaneous manifestations of monogenic auto-inflammatory diseases: an international cohort study from the juvenile inflammatory rheumatism cohort
7 Measuring atopic eczema control and itch intensity in clinical practice a consensus statement from the harmonising outcome measures for eczema in clinical practice (HOME-CP) initiative
8 Apremilast in recalcitrant cutaneous dermatomyositis: a non-randomised controlled trial
9 Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1 Delays in the surgical treatment of melanoma are associated with worsened overall and melanoma specific mortality: a population based analysis
2 Drug survival with effectiveness and safety of treatment with guselkumab, ixekizumab, secukinumab, ustekinumab and adalimumab in patients with psoriasis
3 Sudden conjunctivitis, lymphopenia, and rash combined with haemodynamic changes (SCORCH) after trimethoprim-sulfamethoxazole use: a case series study of a hypersensitivity reaction
4 Patch testing in fixed drug eruptions: a 12 year retrospective study
5 Neo-adjuvent Cemiplimab for Stage II to IV cutaneous squamous cell carcinoma
6 2 Phase 3 randomised controlled trials of Ruxolitinib cream for vitiligo
7 NICE guidelines for pembrolizumab for resected stage 2B or 2C melanoma
8 Trial of intravenous immunoglobulin in dermatomyositis
9 Reflective case history-St George’s hospital records
10 Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1 Short courses of ciclosporin can induce long remissions in chronic spontaneous urticaria
2 Isotretinoin laboratory monitoring in acne treatment- a Delphi consensus
3 Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study
4 Clinical features and natural course of paediatric longitudinal melanonychia: a retrospective cohort study in Korea
5 The association between frontal fibrosing alopecia, sunscreens and moisturizers: a systematic review and meta-analysis
6 What exactly are odds ratios?
7 Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles
1 Real life impact of immunologic tests to predict relapse after treatment cessation in patients with bullous pemphigoid: a French multicentre retrospective study
2 Comparison on permethrin based treatment strategies against scabies in infants and young children
3 Adjuvant radiotherapy may not significantly change outcomes in high risk squamous cell carcinoma with a clear surgical margins: a systematic review and meta-analysis
4 Risk of invasive SCC after treatment of actinic keratosis: a secondary analysis of a RCT trial data
5 Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic disease
6 Clinicoprognostic implications of head and neck involvement by mycosis fungoides: a retrospective cohort study
7 Treatments and outcomes of generalised pustular psoriasis: a cohort of 1516 patients in a nationwide inpatient database in Japan.
8 NICE: Abrocitinib, Tralokinumab, or Upacitinib for treating moderate to severe atopic dermatitis
9 Inhibition of TNF improves conventional steroid therapy for SJS/ TEN in a cohort of patients
10 Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles.
1) Paediatric mycosis fungoides-characteristics, management and outcomes with particular focus on the folliculotrophic variant
2) Topical imiquimod verses surgery for vulval intraepithelial neoplasia: a multicentre, randomised, phase 3, non-inferiority trial
3) Longtitudinal atopic dermatitis endotypes: an atopic march paradigm that includes black children
4) Cutaneous polyarteritis nodosum diagnosis and treatment: a retrospective case series
5) Secukinumab dosing every 2 weeks demonstrated superior efficacy compared to dosing every 4 weeks in patients with psoriasis weighing 90Kg or more: results of a randomised controlled trial
6) Open notes and dermatopathology reports: a pathway to increasing patient autonomy, not confusion
7) Isla Galpin. Violin Sonata in G minor, 1st and 2nd movement by Eccles.
1 Association of spironolactone use with risk of cancer: systematic review and meta-analysis
2 British association of dermatologists guidelines for the management of people with chronic urticaria
3 Focus on oral minoxidil for androgenetic alopecia and alopecia areata
4 Evidence check: How long to leave between stopping tetracyclines and starting isotretinoin?
5 Monkeypox goes global: why scientists are on alert
6 Birth outcomes in women who have taken hydroxychloroquine during pregnancy: a prespective cohort study
7 Dermatological guidelines for monitoring methotrexate treatment reduce drug survival compared to rheumatological guidelines
8 Advanced Strings, Sir William Perkins’s school - Isla Galpin (1st violin), Hayun Lee (2nd violin), Miss Townsend (viola), Amélie Christian (cello) - Chanson de Matin by Edward Elgar (1857–1934)
Assessment of the diagnostic accuracy of baseline clinical examination and ultrasonographic imaging for the detection of lymph node metastasis in patients with high risk cutaneous squamous cell carcinoma of the head and neck.
Efficacy of treatments for cholestatic pruritus: a systemic review and meta-analysis.
Efficacy and safety profile of oral spironolactone use for androgenic alopecia: a systematic review.
Lack of association of atopic dermatitis severity and worsening during pregnancy: a cross sectional study.
Tofacitinib as a treatment for refractory dermatomyositis: a retrospective study from 2 academic medical centres.
Superficial basal cell carcinoma., think deeper: Step sectioning of skin biopsy specimens yields 14% more aggressive subtypes.
Food anaphylaxis in the UK: Analysis of national data 1998 to 2018.
Budesonide capsules for peristomal pyoderma gangrenosum.
COVID perniosis-a true phenomenon?
Advanced Strings, Sir William Perkins’s school - Isla Galpin (1st violin), Hayun Lee (2nd violin), Miss Townsend (viola), Amélie Christian (cello) - Chanson de Matin by Edward Elgar (1857–1934)
1) Adverse pregnancy and maternal outcomes in women with hidradenitis suppurativa
2) Infections in children and adolescents treated with Dupilumab in paediatric clinical trials for atopic dermatitis-a pooled analysis of the trial data
3) Biological disease modifying antirheumatic drugs may mitigate the risk of psoriatic arthritis in patients with chronic plaque psoriasis
4) The spread of resistant tinea and the ingredients of a perfect storm
5) Asynchronous telemedicine for isotretinoin management: a direct care pilot
6) BAD guidelines for the management on people with vitiligo 2021
7) Facial discoid dermatosis
8) Timing of introduction to solid food, growth and nutrition risk in later childhood
1) Effect of therapeutic drug monitoring verses standard therapy during maintenance infliximab therapy
2) Dupilumab in children with uncontrolled moderate-to-severe asthma
3) Fibrosing alopecia in a pattern distribution
4) Multi-state model for predicting ocular progression in Acute Stevens-Johnson syndrome/ Toxic Epidermal necrolysis
5) Specific features of amoxicillin-associated Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome: a nationwide study
6) Phase 3 Trials of Tapinarof cream for Plaque Psoriasis
7) Trial of Spesolimab for Generalised Pustular Psoriasis
8) Deficiency of adenosine deaminase 2: updates on the phenotype, genetics, pathogenesis and treatment
9) Amazon Care has launched in the US, we speculate that a UK launch is not too far away…
10) Advanced Strings, Sir William Perkins’s school - Isla Galpin (1st violin), Hayun Lee (2nd violin), Miss Townsend (viola), Amélie Christian (cello) - Chanson de Matin by Edward Elgar (1857–1934)
What’s new in the updated BCC guidelines?
Lupus anticoagulant single positivity during the acute phase of COVID-19 is not associated with venous thromboembolism or in-hospital mortality.
Purpura as an indicator of severity in Drug-induced Hypersensitivity Syndrome/ DRESS
Electrocardiogram as a Lyme disease screening test.
Prevalence of mastocytosis and hymenoptera venom allergy in the United States.
Evaluation of thalidomide treatment of patients with chronic Erythema Multiforme.
VEXAS-Clinical presentation of a newly described somatic, auto-inflammatory syndrome.
Should all babies have their genome sequenced at birth?
Measles outbreaks likely as COVID pandemic leaves millions of world’s children unvaccinated, WHO warns.
Advanced Strings, Sir William Perkins's school- Isla Galpin (1st violin), Hayun Lee (2nd violin), Miss Townsend (viola), Amélie Christian (cello) - Chanson de Matin by Edward Elgar (1857–1934)
Edited by Drs L Ferguson and Z Jiyad.
Narrated by Dr V Pinder.
1) Evaluation of watchful waiting and tumour behaviour in patients with BCC
2) Methotrexate hampers immunogenicity to BNT162B2 MRNA COVID vaccine in immune mediated inflammatory disease
3) Diagnostic utility of circumferential peripheral globules under dermoscopy in adults
4) The safety and immunologic effectiveness of live varicella zoster vaccine in patients receiving anti-TNF inhibitor therapy
5) A systematic review of the impact of genetic testing for familial melanoma i) primary and secondary preventative behaviours ii) psychosocial outcomes and attitudes
6) Skin adverse events related to PPE: a systematic review and meta-analysis
7) Cutaneous findings in Fanconi's anaemia
8) Adenopathy and extensive skin patch overlying plasmocytoma (AESOP): 2 morphological variants.
Advanced Strings, Sir William Perkin's school- Isla Galpin (1st violin), Hayun Lee (2nd violin), Miss Townsend (viola), Amélie Christian (cello) - Chanson de Matin by Edward Elgar (1857–1934)