Global T cell Expert Consortium: Recent Episodes
Global T cell Expert Consortium
This podcast series is an educational resource initiated and driven by the Global T cell Expert Consortium, a group of experts in T cells, immunology, vaccine development and public health. The consortium are committed to educating on T cells and advancing the frontiers of T cell research. The GTEC is sponsored by Oxford Immunotec.
In this third episode in an exciting podcast series from the GTEC on pandemic preparedness, Peter Openshaw, Professor of Immunology at Imperial College London (and former President of the British Society for Immunology), and special guest Dr Amesh Adalja, Senior Scholar at the Johns Hopkins Center for Health Security and Adjunct Assistant Professor at the Johns Hopkins Bloomberg School of Public Health, discuss how we can translate scientific research into pandemic preparedness.
Our experts discuss their involvement in helping combat the COVID-19 pandemic, and how important it is to incorporate emerging scientific evidence into policy and real-world solutions. They also highlight lessons learned from managing the COVID-19 pandemic and summarise what is needed to prepare for future pandemics.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content and will foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
Prof. Openshaw of Imperial College London is participating in this podcast independently, via Imperial Consultants.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in May 2021.
In this special episode in an exciting podcast series from the GTEC, T cell experts Dr Marcus Buggert (Assistant Professor of Infectious Medicine at the Karolinska Institute) and Dr Pranab Haldar (Honorary Consultant Respiratory Physician at the University Hospitals of Leicester NHS Trust), discuss T cells, immunity, and clinical perspectives.
In this episode our experts start by discussing their shared interest in the study of infectious diseases and immunology. Next they summarise what we know about immunity to SARS-CoV-2, including the role of T cells and antibodies in immune protection. Finally, they discuss the currently available techniques to assess the immune response to infectious diseases.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in April 2021.
In Episode 4 of the podcast series from the GTEC on T cells and vaccine efficacy, Helen Fletcher, Professor of Immunology at the London School of Hygiene & Tropical Medicine, and Katie Flanagan, Professor of Vaccinology and Immunology and Director of Infectious Diseases for the North and Northwest of Tasmania, discuss vaccine efficacy in different patient demographics.
Prof. Fletcher and Prof. Flanagan discuss how study populations are selected for clinical trials and how real-world patient populations may differ from those evaluated in randomised clinical trials. They also address how vaccine efficacy may be affected by differences in patient characteristics between clinical trials and real-world clinical practice and what role T cells may have in evaluating efficacy in different patient populations.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in April 2021.
In this special episode in an exciting podcast series from the GTEC, meet T cell experts Prof. Alessandro Sette and Prof. Daniela Weiskopf as they discuss their research into T cells and the COVID-19 pandemic at La Jolla Institute for Immunology, USA.
Our experts introduce their areas of research, highlight their contributions during the COVID-19 pandemic, and share key learnings for future pandemic preparedness.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and will foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in March 2021.
In Episode 3 of the podcast series from the GTEC on T cells and vaccine efficacy, Helen Fletcher, Professor of Immunology at the London School of Hygiene & Tropical Medicine, and Dr Satwik Kar, an immunologist from Oxford Immunotec, discuss how the long-term efficacy of vaccines can be monitored.
Prof. Fletcher and Dr Kar give an overview of how vaccines provide us with lasting immunity, and the crucial role of memory T cells and B cells in long-term immune protection. They highlight the importance of long-term monitoring of vaccine efficacy, and how both clinical trials and real-world clinical practice can provide the necessary data. Prof. Fletcher and Dr Kar summarise the current evidence from SARS-CoV-2 vaccines for lasting protective immunity, and discuss the importance of standardised T cell testing in vaccine efficacy monitoring.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in February 2021.
In this second episode in an exciting podcast series from the GTEC on pandemic preparedness, Peter Openshaw, Professor of Immunology at Imperial College London (and former President of the British Society for Immunology), and special guest Dr Bertalan Meskó, Director of the Medical Futurist Institute, discuss their insights into preparing for an unknown pathogen outbreak.
Our experts describe the increasing role of digital health in pandemic preparedness. Prof. Openshaw and Dr Meskó outline the diagnostic tests needed to be prepared for a pandemic situation and highlight the need for better communication between academia, industry, policymakers and the public.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content and will foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
Prof. Openshaw of Imperial College London is participating in this podcast, independently via Imperial Consultants.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in February 2021.
In this first episode in a new podcast series from the GTEC on pandemic preparedness, Tao Dong, Professor of Immunology at the University of Oxford, and fellow GTEC member Antonio Bertoletti, Professor of Infectious Diseases at the Duke–NUS Medical School, Singapore, discuss their experience of research during the COVID-19 pandemic.
Our experts provide an overview of how the pandemic unfolded in their respective locations. Professors Dong and Bertoletti discuss the impact of the coronavirus disease outbreak on the research community and highlight the importance of T cells in understanding more about COVID-19 immunology. Our experts reveal what this pandemic has taught us and suggest best practices when it comes to preparing for future pandemics.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content and will foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in February 2021.
Helen Fletcher, Professor of Immunology at the London School of Hygiene & Tropical Medicine, hosts the second episode in the podcast series from the GTEC on T cells and vaccine efficacy. In this episode, Prof. Fletcher is joined by Paul Moss, Professor of Haematology at the University of Birmingham and a fellow member of the GTEC. Professors Fletcher and Moss discuss the immunological implications of vaccine administration scheduling.
Our experts provide an overview of how the immune system responds to vaccination, and discuss how booster shots contribute to lasting immunity. Professors Fletcher and Moss review the currently available SARS-CoV-2 vaccines and their vaccination schedules, and discuss what the impact of extended dosing schedules (as seen in the UK, for example) may have on immunity and vaccine efficacy. Our two speakers also discuss the role of T cell testing in monitoring the efficacy of current and future vaccine schedules.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in February 2021.
Helen Fletcher, Professor of Immunology at the London School of Hygiene & Tropical Medicine, hosts the first episode in a new podcast series from the GTEC on T cells and vaccine efficacy. In this episode, Prof. Fletcher is joined by Dr Ravina Kullar, an infectious disease pharmacist, epidemiologist and research consultant, to discuss the immunological implications of new SARS-CoV-2 variants.
Our experts explain how mutations can arise in viruses, and how viral mutations could impact the host immune response. Prof. Fletcher and Dr Kullar provide an overview of the recently discovered SARS-CoV-2 variant strains, and discuss their potential impact on the infectivity of SARS-CoV-2, the immune response to SARS-CoV-2, and efficacy of current vaccines against SARS-CoV-2. Our speakers also explain how T cell diagnostic tests could play a role in monitoring the protection provided by vaccines.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
The COVID-19 pandemic is a rapidly changing situation: the content of this podcast was correct at time of recording in January 2021.
In this episode, Dr Ravina Kullar, an infectious disease pharmacist, epidemiologist and research consultant, and Prof. Helen Fletcher, Professor of Immunology at the London School of Hygiene & Tropical Medicine, come together virtually to discuss the role of T cells in vaccine development.
During this 30-minute educational podcast, our experts explain the basics of vaccines: what they are, how they are developed and why they are so important to global public health. Dr Kullar and Prof. Fletcher discuss the mechanisms of immunity, how T cell and antibody responses are generated by the body, and how vaccine development programmes can harness T cell and antibody responses using diagnostic assays. Our speakers highlight the importance of having QC-validated, standardised T cell response assays available, and provide an overview of the roles T cell responses may play in vaccine development.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.
In Episode 2 of the Global T cell Expert Consortium (GTEC) podcast series, Dr Andrew Makin (Vice President of Medical Affairs, Oxford Immunotec) welcomes Prof. Danny Altmann (Professor of Immunology, Imperial College London) to talk about the role of T cells in the response to SARS-CoV-2.
Prof. Altmann describes how the immune system reacts to viral infections, including how antibody and T cell responses are generated and the ways in which they differ. This podcast also highlights the importance of both antibodies and T cells in the immune response their interdependence on one another and the timings of these responses during infections. Prof. Altmann explains the role of different T cells in SARS-CoV-2 infection, including the roles of CD4, CD8 and memory T cells. Dr Makin and Prof. Altmann discuss how T cell responses can be measured using assays such as ELISPOT, including details of the large-scale Public Health England EDSAB-HOME study which used an ELISPOT assay to analyse the epidemiology of SARS-CoV-2. They also emphasise the importance of standardised, reproducible T cell testing, and the impact of such tests on T cell and immunology research.
This podcast was developed by the Global T cell Expert Consortium (GTEC), an initiative set up to bring together experts in T cells, vaccines, immunology and public health worldwide, with the aim of becoming the leading voice in T cell research during and beyond the current COVID-19 pandemic. The GTEC will educate on T cells and vaccine development through the release of publicly available educational content, and foster collaborative research efforts to address the unmet needs and unanswered questions in T cell research and vaccinology. This initiative is sponsored by Oxford Immunotec.