How to Launch an Industry: Recent Episodes
Marcu & Arora
The cannabis industry is expanding more rapidly than ever before. Hot on its heels is the emerging psychedelics industry. What comes next? Our podcast brings listeners entertaining and insightful discussions with leaders in science, medicine, and health along with their pioneering business counterparts to discuss research and current events.
An exciting discussion about AI in drug discovery from a highly cross disciplinary group of experts covering natural products chemistry, biotechnology, computer science, intellectual property, and standards. The episode was recorded live in the beautiful surroundings of the Mendocino County coast in northern California. The scenery provided inspiration for the game segment “guess that native plant” and the pop lit segment about ocean based drug discovery. Both excellent warm ups for our more in depth discussion on practical applications of AI in drug discovery and where gaps still exist.
Group
Nigam B. Arora, PhD (moderator)
Del Potter, PhD
Graham Pechenik, JD
Jackie von Salm, PhD
Jonathan McCoy
David Vaillencourt, MSc
Game Segment (2:57)
Guess that Native Plant - Mendocino County California Edition
Regulatory News (13:13)
Why Scientists are Searching the Ocean for New Drugs
Rapid Fire Science (32:43)
Artificial Intelligence for Natural Product Drug Discovery
Credits:
Cover photo by AnnaMarie Cicitta. Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
This episode covers the July 27th House Oversight Committee within the Health Care and Financial Services Subcommittee titled “Hemp in the Modern World: The Yearslong Wait for FDA Action”. The group also discusses new data from analyzing Delta-8-THC products on the market.
Our resident GMP and standards expert, David Vaillencourt, moderates this episode. We’re also joined by special guest Gillian Schauer, PhD, who testified before the House Oversight Committee. Dr. Schauer is the Executive Director of the Cannabis Regulators Association (CANNRA), a non-partisan association of government agencies that regulate cannabis and hemp across 45 states and US territories. Prior to her leadership at CANNRA, she spent more than a decade working with federal agencies - including the CDC and NIH on cannabis related policy, research, and public health.
As usual, HLI co-hosts Jahan Marcu, PhD and Nigam B. Arora, PhD round out the group discussion. If you are a new listener, Dr. Arora advises multistate and multinational cannabis companies as well as psychedelic manufacturers and venture capital firms on translating science into business decisions as the Co-Founder of Marcu & Arora. Dr. Jahan Marcu, the other half of the Marcu & Arora leadership team, has been applying his knowledge on the endocannabinoid system for over 20 years - advising regulatory bodies, providing expert witness services in complex cannabinoid related cases, and has published dozens of articles on cannabinoids and psychedelics.
Sponsor
CloudLIMS
Group
David Vaillencourt, MSc (moderator)
Gillian Schauer, PhD
Jahan Marcu, PhD
Nigam B. Arora, PhD
Game Segment (5:00)
True or False - Cannabis News Headlines
Regulatory News (20:40)
July 27th House Oversight Committee - “Hemp in the Modern World: The Yearslong Wait for FDA Action”. Congress asks interested parties for information about cannabidiol
Rapid Fire Science (46:40)
Isolation and Characterization of Impurities in Commercially Marketed Δ8-THC Products
Credits:
Cover art by Julia Boot. Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
The third and final episode of our Live from Psychedelic Science series focuses on culture. Our team interviewed eight speakers and exhibitors from the conference hailing from various walks of life. The episode kicks off with a psychedelics comedian and rolls into discussion with an experienced energy worker. Next we hear from two non-profit leaders whose organizations champion indigenous reciprocity and fund research to combat the opioid epidemic respectively. From there we engage with two students pursuing advanced science degrees while simultaneously working in the space. Winding down the episode, we hear from a psychedelics attorney focused on the non-profit sector. To close it out, we have HLI day one David Vaillencourt interviewing Co-Host of the show Dr. Nigam B. Arora.
Interviewers
Nigam B. Arora, PhD
Amber Wise, PhD
Callie Hoffman
Neil Ritter, PhD
David Vaillencourt, MSc
Interviewees
Sara Rose Siskind - Comedian and founder of Hello SciCom (3:23)
Taylor Bratches, MFA - Energy worker at Agne and Soma and performing work study at SoundMind Institute (16:55)
Lorien Chavez - Development and Operations Officer at Chacruna Institute (26:12)
Anna Symonds, MA - Executive Director of The Etheridge Foundation (34:14)
Victor Acero - Co-founder of Intercollegiate Psychedelics Network & Penn Psychedelics Collaborative (42:55)
Ben Cyrulnik - Graduate student in psychoactive pharmaceutical investigation program at University of Wisconsin Madison (51:20)
Victoria Litman, JD - Principal at Litman Law and adjunct professor at Roger Williams School of Law (57:30)
Nigam B. Arora, PhD - Co-host at How to Launch an Industry, CEO at Aromarc Therapeutics (1:02:33)
Credits:
Cover art by Julia Boot. Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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The second episode of our three part series, Live from Psychedelic Science, focuses on business. We interview seven founders and initiative leaders operating across marketing, legal, standards, drug development, insurance, and ESG. Listeners get the inside scoop from these industry leaders sharing their experience, both personally and professionally, from attending the largest psychedelic conference in modern history. We also hear about challenges they’ve faced and if changes in the industry are making those issues better or worse.
Interviewers
Nigam B. Arora, PhD
Neil Ritter, PhD
Interviewees
John Shute, MBA - CEO and co-founder at Puf Creative (3:39)
Rebecca Lee Whiting, JD - Founder at Epigram Legal (12:49)
David Vaillencourt, MSc - CEO and founder at The GMP Collective (21:56)
Chris Witowski, PhD - CEO and co-founder at Psilera (32:17)
Kimberely Chew, JD - Co-lead of the psychedelics and emerging therapies practice at Husch Blackwell LLP (41:29)
Leslie Nylund, CPCU - Managing Director of TheraCover at Baldwin Risk Partners (49:17)
Marc Ross, JD - Chief Instigator at Needle Partners (57:37)
Credits:
Cover art by Julia Boot. Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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The first episode of our three part series, Live from Psychedelic Science, focuses on research. We interview five leaders in the field whose work runs the gamut from generating novel molecules to patient care. We kick off the episode with back to back chemist entrepreneurs who work at the cutting edge of psychedelic drug development. From there we hear from the psychedelics program manager at one of the world’s largest medical research institutions. Next, we get an international perspective by engaging with Brazil’s leading clinical researcher of ayahuasca, pure DMT, and ketamine. We close out the episode with an experienced integrative medicine doctor and patient advocate.
Interviewers
Nigam B. Arora, PhD
Neil Ritter, PhD
Interviewees
Andrew Bartynski, PhD - VP of Operations at Alexander Shulgin Research Institute (2:58)
Jackie von Salm, PhD - Co-founder and CSO at Psilera (14:31)
Lauriane Sibileau, MSc - Program Manager at Center for Neuroscience of Psychedelics at Mass General Hospital (25:13)
Nicole Galvão-Coelho, PhD - Professor of Physiology & Behavior at Federal University of Rio Grande do Norte and Adjunct Professor at Western Sydney University (34:51)
Harry McIlroy, MD - Integrative Medicine Doctor at BioReset Medical and Chair of the Board of Directors at Chacruna Institute (52:58)
Credits:
Cover art by Julia Boot. Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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This episode features two special guests, David Bronner and Angela Carter, ND, discussing hot topics in drug policy with co-hosts Jahan Marcu, PhD, and Nigam B. Arora, PhD. David Bronner is the CEO of Dr. Bronner’s, the highest scoring B Corp in the world among companies dedicated to positive social and environmental impact over profit motive. Additionally David has been dedicated to the responsible integration of cannabis and psychedelics into global culture since 1995, and on the board of MAPS since 2015. Angela Carter, ND is an Oregon based naturopathic doctor, genderless being of universal light, and social & health justice advocate who works actively with psychedelic medicines. The group warms up with a game examining old idioms and new headlines. Next, the group discusses a story from VICE Magazine about a Canadian drug store testing the limits of decriminalization laws. The final segment focuses on a recent publication about health equity in psychedelics and mental health.
Group
Jahan Marcu, PhD (moderator)
David Bronner
Angela Carter, ND
Nigam B. Arora, PhD
Today’s Game (2:00):
Old Idioms and New Headlines
News and Popular Literature (20:00):
VICE Magazine Reports - Store Selling Heroin, Meth, and Cocaine Just Opened in Canada
Rapid Fire Science (42:10):
Equity and Access to Psychedelics Treatment in Dementias and Neurodegenerative Diseases
Credits:
Cover art by Clancy Cavnar, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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We bring you six interviews with leaders in the psychedelics industry who will be presenting at the Psychedelic Therapeutics & Drug Development Conference taking place in San Francisco on May 15 & 16, 2023. The episode spans a variety of topics, each crucial to the development of psychedelic medicines. We begin with government funded drug discovery research, followed by a look at the clinical research landscape both in academia and industry settings. Next our interviewees discuss legal considerations in the field of psychedelic drug development, from both regulatory and intellectual property lenses. To close the episode out we discuss trends in the current investment landscape. Be sure to check out the full conference agenda at psychedelics-conference.com and join us in person at the event as we continue these discussions!
Moderators
Nigam B. Arora, PhD (moderator)
Jahan Marcu, PhD (moderator)
Guests
Ryan Gumpper, PhD - Roth lab at UNC Chapel Hill and DARPA’s Focused Pharma Initiative
Joshua D. Woolley, MD, PhD - UCSF Weill Institute for Neurosciences & Translational Psychedelic Research Program
Sabrina Ramkellawan & Jaspreet K. Grewal, MBA - AxialBridge
Kimberely Chew, JD - Husch Blackwell
Graham Pechenik, JD - Calyx Law
Tim Schlidt - Palo Santo
Credits:
Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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We welcome a true pioneer of psychedelics science, Dr. David Nichols, to the show. The episode begins with panelists matching quotes about psychedelics to the famous person who gave the quote, and the substance they were referring to. The pop literature segment explores a timeline of psychedelic events from 1990 - present. Dr. Nichols provides a fascinating look into multiple landmark studies that were enabled by his lab’s willingness to synthesize the required psychedelic compounds. For the peer reviewed segment the group assesses a recent publication about cutting edge methods for measuring the acute brain action of psychedelics. This inspires a conversation about the practical utility of such tools in specific research areas and for driving the field forward.
Special thanks to the sponsor of this episode - Psychedelic Therapeutics & Drug Development Conference, taking place in San Francisco, May 15 & 16, 2023
Episode’s Group:
Nigam B. Arora, PhD (moderator)
David Nichols, PhD
Jackie von Salm, PhD
Jahan Marcu, PhD
Today’s Game (3:03):
Famous Figures and Famous Psychedelics
News and Popular Literature (17:06):
A Timelines of Psychedelic Events - The Third Wave
Bonus from Purdue University - Betsy Gordon Psychoactive Substances Research Collection
Rapid Fire Science (51:51):
Human brain effects of DMT assessed via EEG-fMRI
Credits:
Cover art by Julia Boot, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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We get together for this episode to discuss everything from the legacy of the late Raphael Mechoulam, PhD, to the economics of THC and regulated cannabis. This episode features Joshua Hartsel, PhD and the show begins with a fun look at Dr. Mechoulam’s massive impact on cannabis research. For the second segment, we discuss the issues regarding “THC inflation” - over estimations of potency and lab shopping that are plaguing the industry. This topic inspired the episode cover art which, in a first for HLI, was created using a generative AI tool (DALL·E 2). We end by discussing our interpretation of a recent publication about the economics of the 420 “holiday” and the impact of adult use regulations on medical cannabis operations.
Special thanks to the sponsor of this episode - Queering Psychedelics II Conference by Chacruna Institute
Episode’s Group:
Jahan Marcu, PhD (moderator)
Joshua Hartsel, PhD
David Vaillencourt, MSc
Nigam B. Arora, PhD
Today’s Game (2:25):
Mechoulam’s Legacy - Inspired by an Interview with Ethan Russo
News and Popular Literature (20:00):Inflating THC
Rapid Fire Science (48:25):
Economics of 420
Credits:
Cover art created using DALL·E 2, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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We host Super Bowl XLVII (2013) winner Kelechi Osemele for a sports focused episode! HLI cast member Anna Symonds weighs in heavily having won both the USA Rugby Division I National Championship and Sydney Premiership Championship. The episode begins with a game reviewing shifting cannabis and psychedelics regulations around the world. Next the group discusses the relationship between elite athleticism and psychedelics, spurred by news that NFL quarterback Aarron Rodgers will speak on his personal experiences at Psychedelic Science 2023. The episode wraps up with analysis of a literature review about the therapeutic potential of cannabinoids through a sports medicine lens.
Special thanks to the sponsor of this episode The GMP Collective.
Episode’s Group:
Nigam B. Arora, PhD (moderator)
Kelechi Osemele
Anna Symonds, MA
Hadas Alterman, JD
Today’s Game (2:48):
Shifting Regulations
News and Popular Literature (24:04):Elite Athletes Speak on Experiences with Psychedelics
Rapid Fire Science (42:15):
Therapeutic Potential for Cannabinoids in Sports Medicine: Current Literature Review
Credits:
Cover art by Julia Boot, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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Join us as we blend perspectives on modern medical research with valuable lessons learned through other ways of knowing. Dr. Bia Labate, executive director of Chacruna Institute, and Dr. Harry McIlroy, clinical director at BioReset Medical, help us dissect the many challenges of placebo controls when researching psychoactives. We further discuss educational offerings from Chacruna Institute specifically focused on methods of knowledge production in the psychedelics field. We close the episode by relating an attention grabbing article published in Nature, about a reduction in disruptive research, to psychedelics.
Special thanks to the sponsor of this episode the American Psychedelic Practitioners Association.
Episode’s Group:
Nigam B. Arora, PhD (moderator)
Bia Labate, PhD
Harry McIlroy, MD
Jahan Marcu, PhD
Today’s Game (2:57):
Guess that Psychoactive Plant
News and Popular Literature (14:41):Perspectives and Educational Offerings on Psychedelics Research from Chacruna Institute
Placebo Problems: Boundary Works in the Psychedelic Science Renaissance
Course: Critical Perspectives on Knowledge Production in Psychedelic Science
Rapid Fire Science (44:47):
Nature reports research and patents are becoming less disruptive over time, do psychedelics buck this trend?
Credits:
Cover art by Cleng Sumagaysay, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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We wrap up 2022 with a psychedelics focused episode. Listeners are invited to join the conversation with experts working in legal, standards, research funding, and science aspects of the burgeoning industry. The episode kicks off with a game about infrastructure and the required picks and shovels for building it. We then discuss the importance of standards for psychedelics assisted psychotherapy and the launch of a non-profit organization providing leadership in that area. The episode wraps up with a discussion around indigenous views on the “psychedelics renaissance”, inspired by a recent article published in the journal Anthropology of Consciousness.
Special thanks to the sponsor of this episode the East Fork Cultivars.
Episode’s Group:
Nigam B. Arora, PhD (moderator)
Anna Symonds, MA
Adriana Kertzer, JD
Hadas Alterman, JD
Today’s Game (2:40):
Picks and Shovels of the Psychedelics Industry
News and Popular Literature (24:50):
American Psychedelics Practitioners Association Launches Non Profit
Rapid Fire Science (45:40):
Indigenous Philosophies and the “Psychedelic Renaissance”
Credits:
Cover art by Natalie McKean, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
marcu-arora.com
Experts discuss the science of taking the trip out of psychedelics while maintaining the therapeutic benefits, a conversation inspired by a recent article published in Nature. Psychedelics policy is also addressed with a game that tests our guests' knowledge about opposition and support for proposition 122 in Colorado. The show wraps up with a discussion of best practices for performing research on how cannabis may affect the endocannabinoid system.
Special thanks to the sponsor of this episode the Sheri Eckert Foundation.
Episode’s Group:
Jahan Marcu, PhD
Jeff Chen, MD, MBA
Jackie von Salm, PhD
Amber Wise, PhD
Nigam B. Arora, PhD
Today’s Game (2:15):
Prop 122 Colorado and Psychedelics
News and Popular Literature (19:20):
Taking the Trip out of Psychedelics
Rapid Fire Science (43:50):
Does Cannabis Use Affect Endocannabinoid Levels
Credits:
Cover art by Moksha Marquardt, Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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marcu-arora.com
Join us for a fun, engaging session where we discuss important issues in cannabis testing, alcohol use, and the psychedelic receptorome. This episode was our first recorded in person, and from the beautiful surroundings of the Mendocino County coast in California. The group welcomes first time guests, epidemiologist Teresa Simon, MPH and integrative medicine doctor Harry McIlroy, MD.
Episode’s Group:
Jahan Marcu, PhD
Harry McIlroy, MD
Teresa Simon, MPH
Amber Wise, PhD
Nigam B. Arora, PhD
Today’s Game (2:45):
Cannabis Contaminant Testing with Amber Wise, PhD.
News and Popular Literature (22:00):
Questioning Alcohol with Nigam B. Arora, PhD
Rapid Fire Science (42:00):
Psychedelics and the human receptorome with Jahan Marcu, PhD
Credits:
Podcast audio engineering by Joe Leonardo. Intro music by Buddha by Kontekst. Transition music by K. LOUK. Outro music by Bensounds.
More at:
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marcu-arora.com
This episode starts with a game that tests your knowledge about cannabis sustainability, the environmental impact of hemp operations, and proposed solutions. For our second segment, we discuss reciprocity and sustainability in psychedelics, inspired by an article recently published in Forbes. For our third segment, Rapid Fire Science, we discuss a peer reviewed article, on the serotonin theory of depression, also often referred to as the chemical imbalance theory.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Jackie von Salm, PhD
Joe Leonardo (game segment)
Today’s Game (1:48):
The Environmental Impact of Cannabis
News and Popular Literature (30:15):
Reciprocity and Psychedelics
Rapid Fire Science (37:47):
The Imbalance of the Chemical Imbalance Theory of Depression
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by Illia_boo, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
marcu-arora.com
The group discusses cannabis education, happenings at the FDA, and serotonin syndrome related to psychedelics. There are increasing numbers of universities and colleges offering professional programs and even degrees in cannabis-related areas. Play our game to find the best higher education program for you! In the news segment we dive into surprising big pharma activities with engaging the FDA on cannabis regulations. The show wraps up discussing a review of clinical and mechanistic evidence supporting a hypothesis of potential serotonin related health effects. Join us to learn about cannabinoids, the FDA, and psychedelics.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt, MSc
Today’s Game (2:50):
What do You Know About Cannabis Education?
News and Popular Literature Links (27:00):
Big Pharma and the FDA
FDA Officials Wrestle with CBD
Rapid Fire Science Study Links (37:47):
Serotonin Toxicity of Serotonergic Psychedelics
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by Illia_boo, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
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marcu-arora.com
Join us for a conversation about novel drug substances! The topics range from clinical research to the forces within the cannabis industry’s patent and intellectual property issues. In this episode’s game, Dr. Marcu reads clues about cannabis news and political events, and participants have to guess the fake canna-news article. For the news segment, we discuss 18 psychedelics clinical trials that have received significant media attention, and whether they can possibly deliver on the hype. This episode's peer reviewed article is an analysis of the cannabis patent landscape and delves into how common practices may test the limits of the regulated market.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Anna Symonds, MA
Today’s Game (2:00) :
Cannabis News Quiz
News and Popular Literature Links (11:20):
18 Clinical Trials That Could Make or Break the Future of the Psychedelics Industry
Rapid Fire Science Study Links (39:40):
High Risk, High Reward: Patent Law’s Effects on the Medical Marijuana Industry
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
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marcu-arora.com
Join us for a psychedelics-focused conversation! Listeners of this podcast episode will enjoy discussions about the basics of serotonin and dopamine, mechanisms of action for psychedelics and antidepressants, different types of patents and their implications, and a dissection of clinical data on the subjective effects of LSD and psilocybin.
In this episode’s game, Dr. Marcu reads a statement about a drug and panelists guess if it's in reference to a psychedelic compound or an antidepressant. For segment 2 we discuss an article written by Lauren Wilson, published by Lucid News, entitled, “A New Database Seeks to Prevent ‘Bad’ Psychedelic Patents.” This episode's peer reviewed article is a clinical comparison of LSD and psilocybin published in the Nature journal Neuropsychopharmacology in 2022. This episode features Jahan Maruc, PhD, Nigam B. Arora, PhD, Sara Jane Ward, PhD and Amber Wise, PhD.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Sara Jane Ward, PhD
Amber Wise, PhD
Today’s Game (2:05) :
In Reference to Psychedelics or Antidepressants?
News and Popular Literature Links:
New Database to Prevent ‘Bad’ Psychedelics Patents
Rapid Fire Science Study Links:
Direct Comparison of the Acute Effects of Lysergic Acid Diethylamide (LSD) and Psilocybin
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by illia_boo, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
marcu-arora.com
Join us for a cannabis-focused episode. Our discussion covers some of the politics around federal legalization in the United States, DEA licensed cultivation operators, and research into the potential for cannabis markets in Ukraine and other parts of Eastern Europe. The episode includes discussion about recent trends regarding cannabis and hemp policy in Eastern Europe, a knowledge and attitude surveys of Ukrainians regarding cannabis, and how new hemp and cannabis regulations in the Ukraine could help meet the increasing demand for pediatric epilepsy treatments and alternative pain medications. This episode features Jahan Maruc, PhD, Nigam B. Arora, PhD, and David Vallencourt, MSc.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
David Vaillencourt, MSc
Today’s Game (2:05) :
The MORE you know the less you Act - Can you guess which quotes from politicians around the recent federal cannabis legalization activity are real and which are fake?
News and Popular Literature Links:
Can DEA backed cannabis growers deliver on drug development?
Rapid Fire Science Study Links:
Assessment of a prospective cannabis market in Ukraine
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by illia_boo, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
marcu-arora.com
This episode features Jackie von Salm, PhD, Anna Symmonds, MA, Jahan Marcu, PhD and Nigam B. Arora, PhD. The podcast starts with a game about cannabis mergers, testing our guest’s knowledge of the recent merger between Cresco Labs and Columbia Care. Then the group buckles up for a discussion about risks related to cannabis-based vape products, and new research investigations on user experiences with various psychedelic substances.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Anna Symonds, MA
Jackie von Salm, PhD
Today’s Game (1:50)) :
Three Truths and a Lie: The recent merger between Cresco and Columbia Care; is it the largest merger to date…or is it??
News and Popular Literature Links:
Cannabis product recall leads to lawsuit in Pennsylvania over safety of vape products.
Rapid Fire Science Study Links:
Analysis of experiences with various classes of psychedelic substances
Credits:
Podcast audio engineering by Joe Leonardo, Cover art by illia_boo, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds.
More at:
howtolaunchanindustry.com
marcu-arora.com
Amber Wise, PhD, hosts this episode. Dr. Wise moderates a discussion between Miyabe Shields, PhD, Julie Kowalski, PhD, Nigam B. Arora, PhD, and Jahan Marcu, PhD. The group shares insights into psychedelics based health care as well as discussing issues related to the cannabis industry such as the common mistake everyone makes when miscalculating total THC. We turn to the peer reviewed literature to examine data on whether or not psychedelics can change your religious beliefs and the latest genetic data about the origin of cannabis. Stay tuned for the game, Psych Out, at the end of the show to see if you can guess the bogus piece of psychedelics science.
Episode’s Group:
Amber Wise, PhD (moderator)
Miyabe Shields, PhD
Julie Kowalski, PhD
Jahan Marcu, PhD
Nigam B. Arora, PhD
News and Popular Literature Links:
The Promises and Perils of Psychedelic Health Care (3:50)
Totally Miscalculated: The total THC problem (26:00)
The Curious Case of CBN and Sleep (45:10)
Rapid Fire Science Study Links:
Psychedelics Alter Metaphysical Believes (1:05:45)
Large-scale Whole-genome Resequencing Unravels the Domestication History of Cannabis sativa (1:15:10)
Today’s Game (1:26:00) :
Today’s game is Psychedelic Pysch-out! Can you guess the fake research article before the panelists?
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Natalie McKean, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
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marcu-arora.com
Jahan Marcu, PhD and Nigam B. Arora, PhD are joined by Sara Jane Ward, PhD and Jim Mitchell, PhD the Vice President, API Research and Development at Benuvia Manufacturing. The discussions begin with a deep dive into cannabis and psychedelics policy and research developments, highlighting that it feels as though psychedelics are skipping the line, passing cannabinoids, into the regulatory party. For rapid fire science we discuss cutting technology around synthesizing psychedelic compounds and cannabinoids. Learn why you should care about modern chemistry and its approaches to psychedelics and cannabinoid drug manufacturing needs for clinical research.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Sara Jane Ward, PhD
Jim Mitchell, PhD
News and Popular Literature Links:
Cannabis Legalization Gets Cold Shoulder (3:00)
The Psychedelic Landscape: Pharma, tech, decrim, other (17:40)
Additional Resource: https://psilocybinalpha.com
Therapy for the UK - “It's coming sometime and maybe” (32:35)
Rapid Fire Science Study Links:
Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, baeocystin, norpsilocin, and aeruginascin (45:50)
A Novel and Practical Continuous Flow Chemical Synthesis of Cannabidiol (CBD) and its CBDV and CBDB Analogues (1:06:55)
Today’s Game (1:26:00) :
Welcome to today’s GAME, today our group will be playing for the grand prize of helping to expand scientific thought. Today’s game is Name That Drug! - The moderator summarizes a case report about psychedelics, cannabis, or another commonly used drug; the participants must guess which drug, either de novo or from four choices. It's not whether you guess the correct drug but how you ‘think’ through this game.
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Jahan Marcu, PhD moderates the discussion with Nigam B Arora, PhD, David Vaillencourt, MSc from the GMP collective with special guest Gene Ray MSc, Lab Manager at Garden Remedies. We discuss new research on stupidity, psychedelic healthcare investments, and how drug testing culture has permeated many levels of society. FOr our research article review, we rapid fire our thoughts about ibogaine and the behavioral economics on the demand and use of cannabis. Stick around for our newest game, “Don’t be a Square.” In the game, Jahan reads a poem and panelists have to guess which drug Alan Ginsburg was experimenting with, when he wrote the poem.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Gene Ray, MSc
David Vaillencourt, MSc
News and Popular Literature Links:
What is Stupidity? And is it a Psychological or Social Issue? (2:50)
Investors Turn Towards Psychedelic Healthcare Companies. (11:00)
Will Michigan be the First State to Legalize Psychedelics? (23:45)
Amazon to Solve their Worker Shortage by Abolishing THC Drug Testing (34:55)
Bonus resource: Dr. Marcu’s article on cannabis impairment: https://cannabusiness.law/cannabis-impairment-and-driving-legal-and-medical-considerations/
Rapid Fire Science Study Links:
Dark Classics in Neuroscience - The Adverse Events of Ibogaine in Humans: An updated systematic review of the literature (2015–2020). (47:00)
Getting High to Cope with COVID19 (1:04:10)
Today’s Game (1:20:05) :
Welcome to today’s GAME, today our group will be playing for the grand prize of helping to expand scientific and cultural thought. Welcome to “Don’t be a Square”. Dr. Marcu reads a poem, and the panelists along with the audience tries to guess which substance the author was taking or talking about.
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Natalie McKean, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Jahan Marcu, PhD and Nigam B. Arora, PhD host a conversation with Vertosa’s CSO Harold Han, PhD and their Chief Innovation Officer, Austin Stevenson, MSc. In this episode we focus on how cannabis and psychedelics companies keep their businesses moving forward with fundraising, partnerships, and expanding operations. Join us for an extensive discussion on how experts expand cannabis and hemp businesses. We explore the pros and cons of making a quick buck or having ownership in different types of businesses. Followed by an analysis of two scientific papers looking at cannabis and DMT in beverages. Be sure to stick around for our classic game “Name That Drug!”, where panelists have to guess the drug based on clues from a case report.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Harold Han, PhD
Austin Stevenson, MSc
News and Popular Literature Links:
Psilera Raises $2.5 Million Focused on DMT (2:30)
Cannabis Companies Looking to Grow Have More Options Than Ever? (10:30)
Heroic Hearts Project Announces New Study with Imperial College London into the Physiological and Psychological Effects of Psilocybin on Veterans.(32:25)
Rapid Fire Science Study Links:
Innovative and Emerging Applications of Cannabis in Food and Beverage Products: From an illicit drug to a potential ingredient for health promotion. (46:30)
Stability Evaluation of DMT and Harmala Alkaloids in Ayahuasca Tea Samples. (1:03:30)
Today’s Game (1:20:05) :
Welcome to today’s game, “Name That Drug!”. Can you guess the correct answer faster than the panelists? Be sure to listen to the end to find out.
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art bySelina Lee, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Today’s discussion features Jahan Marcu, PhD, Nigam B. Arora, PhD, David Vaillencourt, MSc., with special guests Kim Napoli, JD, and Marc Ross, JD from the law offices of Vicente Sederberg. We start off by discussing news around the FDA and CBD. Then Marc Ross shares insights into his article “Environmental, Social, & Governance: The Perfect Storm for the Cannabis Industry.” This leads to a social equity discussion that casts a wide net and Kim Napoli offers advice for companies about getting educated and competent about social equity. Our two research articles focus on cannabis oceanic boundlessness and pediatric use of cannabis in oncology. Be sure to check out our game, testing your knowledge about blunt smoking user characteristics from a study supported by NIDA.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Kim Napoli, JD
Marc Ross, JD
David Vaillencourt, MSc.
Nigam B. Arora, PhD
News and Popular Literature Links:
The U.S. Food and Drug Administration Objected to an Application from Charlotte’s Web Holdings Inc. for a CBD Product to be Sold as a Dietary Ingredient (2:45)
Environmental, Social, & Governance: The Perfect Storm for the Cannabis Industry (17:00)
The Future of Mushroom Shops in the Americas (43:30)
Rapid Fire Science Study Links:
Cannabis-induced Oceanic Boundlessness (57:50)
Cannabis Use in Pediatric Cancer Patients: What are they reading? A review of the online literature (1:05:43)
Today’s Game (1:20:05) :
Welcome to today’s game, today our group will be playing for the grand prize of helping to expand scientific thought. Today’s game is three quotes and a lie. We have pulled three quotes from a research article and included one quote that is completely made up. Can you guess which quote is fake? Our article today is by Ream and colleagues, entitled Smoking tobacco along with marijuana increases symptoms of cannabis dependence, published in 2008 in the journal of Drug and Alcohol Dependence. Can you beat the group to guessing which quote is fake?
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art byLili Price, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Marcu & Arora are joined by Anna Symonds, former professional athlete, and the renowned cannabis chemist Dr. Amber Wise. The group discussion focuses on two main topics for this episode. Each are interwoven throughout, starting with public perceptions of psychedelic research, and the factors that influence those perceptions. The other main topic is the use of cannabis in sports. This episode’s game will test your knowledge about THC-O-Acetate.
Thanks to this episode’s sponsor The GMP Collective!
Episode’s Group:
Jahan Marcu, PhD (moderator)
Anna Symonds, MA
Amber Wise, PhD
Nigam B. Arora, PhD
News and Popular Literature Links:
Deuterated DMT Patent is Issued to Small Pharma (2:25)
Psychedelics Research to Begin in Australia with a $40 Million Donation (9:55)
Are Cannabis “Degrees” Legit and Do You Need One to Get into the Legal Cannabis Industry?(20:10)
Rapid Fire Science Study Links:
Cannabis Use and Sport: A systematic review(43:30)
How Psychedelic Researchers’ Self-admitted Substance Use and Their Association with Psychedelic Culture Affect People’s Perceptions of Their Scientific Integrity and the Quality of Their Research(58:07)
Today’s Game (1:24:05) :
Today’s game is called Don’t be an Acetate Hole - two truths and a lie about THC-O-Acetate, a THC analogue that is artificially or semi-synthetically made. Can you tell which statement is the lie?
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
A global episode, with Dr. Jahan Marcu in NYC, Dr. Nigam B Arora in the San Francisco, Sarah Russo in Spain, Sara Jane Ward in Philadelphia, and Joseph Mays in Washington DC. The group discusses our modern myths about the ancient use of psychedelics. Followed by discussions about the implications of a former FDA official joining a major psychedelics company, and water use research on cannabis. For the peer reviewed section of the show the group discusses the psilocybin research pipeline and the impact of cannabis use on male sexual function.Today’s game is a classic psychedelic whodunit, called Name that Drug, where we describe a case report and guess which substance is the culprit.
Thanks to this episode’s sponsor Berkeley Patients Group!
Episode’s Group:
Jahan Marcu, PhD (moderator)
Joseph Mays
Sarah Russo
Sara Jane Ward, PhD
Nigam B. Arora, PhD
News and Popular Literature Links:
How Common was Psychedelic use in Ingenious Cultures vs Ancient Societies (non-indegnenous)? (2:43)
Former FDA-er Joins Cybin (15:10)
Cannabis Farms not as Thirsty as Previously Thought (28:00)
Rapid Fire Science Study Links:
The Therapeutic Potential of Psilocybin (48:35)
The Impact of Cannabis Use on Male Sexual Function: A 10-year, single-center experience (1:11:00)
Today’s Game:
Name that Drug! Dr. Marcu reads a case report and the audience tries to guess the substance. A classic psychoactive whodunnit. Was it cannabis? Was it opioids? Was it a psychedelic compound? Test your critical thinking ability with this segment.
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Join us for a great trip centered around regulatory and scientific decision making. The discussions focus on data vs opinion, in our exploration of the latest news and research. Our big story for this episode is about technology that allows researchers to develop psychedelic medicines, and we host two expert guests to speak on the topic. Dr. Jackie von Salm was recently featured in the Wall Street Journal utilizing a technology platform for psychedelic drug development and Dr. Franklin King who serves as Director of Education and Therapist Training at the Center for Neuroscience of Psychedelics at Massachusetts General Hospital. To close out the episode we’re joined by Sarah Russo to play the game, “Guess that Herb”!
Thank you to Apex Gaming for sponsoring the episode! Listen to the episode for a special discount code just for HLI listeners.
Episode’s Group:
Jahan Marcu, PhD (moderator)
Nigam B. Arora, PhD
Jackie von Salm, PhD
Franklin King, MD
Dave Vaillencourt, MSc
Sara Russo (game segment)
News and Popular Literature Links:
The Doctor Will Sue You Now - DEA psilocybin lawsuit (2:10)
Hai! Japan to Ease Prohibition of Cannabis-containing Products (16:00)
Is Your Compound Hallucinogenic? This sensor could tell you! (28:15)
Rapid Fire Science Study Links:
Psychedelic Psychiatry’s Brave New World (47:30)
Are Researchers Getting the Terms Used to Denote Different Types of Recreational Cannabis Right? - A user perspective (1:04:00)
Today’s Game:
Sarah Russo, author of Herbs for the Apocalypse, joins the group to host the game, “Guess that Herb”. A 20 questions style game that tests your knowledge about herbs.
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Get lost in thought as we discuss patents on psychedelics, and IP issues related to drug combinations. But first we dive into the pros and cons of legalizing magic mushrooms in Canada, the psychological risks of meditation, and an uncertain future for smokable CBD products. For our peer reviewed research discussion, we review data regarding “fickle federal policy” and neural correlates of the shamanic state. This episode features Graham Pechenik, JD, a cannabis and psychedelics patent attorney along with regular cast members Jahan Marcu, PhD, Nigam Arora, PhD, and Sara Jane Ward, PhD.
Thank you to the episode’s sponsor Kight Law.
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Nigam B. Arora, PhD
Sara Jane Ward, PhD
Graham Pechenik, JD
News and Popular Literature Links:
Will Canada Legalize Magic Mushrooms? Exploring the psychedelics industry post-cannabis legalization (2:24)
Lost in Thought: The psychological risks of meditation (14:35)
Shorter article on the subject
The Future is Not Great for Smokable CBD Products (30:00)
Only Losers Patent Using Drugs: Patenting combining cannabis and psychedelics (42:04)
Rapid Fire Science Study Links:
The Consequences of Fickle Federal Policy: Administrative hurdles for state cannabis policies. (53:30)
Neural Correlates of the Shamanic State of Consciousness. (1:04:00)
Today’s Game:
There are many patents on psychedelics out there, some more surprising than others. And today’s game is led by Graham Pechenik, and is called Guess the Fake Patent.You’ll be presented with 3 real patents and one made up- can you guess the fake one?
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Saloni Sinha, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
The group is joined by Etienne Fontan and Sabrina Fendrick of Berkeley Patients Group (BPG) where they serve as the Vice President and Chief Public Affairs Officer (and part time miracle worker) respectively. We discuss cannabidiol (CBD) and the liver, Vice’s coverage of the drug PCP, and a commentary article about trends in psychedelics use between women and men. Highlights of the episode include our lively discussion about Delta-8-THC, and a published study exploring physical health and lifetime psychedelic use. Be sure to stick around for the game at the end of the show, and test your cannabis trivia, with “guess which politician was high when they said this”.
Thank you to the episode’s sponsor Psilera - bringing a new era in mindful medicine.
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Etienne Fontan
Sabrina Fendrick
David Vaillencourt
Nigam B. Arora, PhD
News and Popular Literature Links:
CBD Safe for Liver, End of the Story? (2:37)
PCP was Developed as a Pharmaceutical but Now is Only Used as an Illicit Drug: Let’s compare it to ketamine (13:55)
“You Can’t Regulate What You Don’t Test For”: Delta-8-THC in the news (25:15)
Secondary source - https://ktvz.com/news/oregon-northwest/2021/03/20/olcc-to-limit-use-of-delta-8-thc-other-artificially-derived-cannabinoids/
Report Shows Women More Likely to Use Psychedelics than Men (44:03)
Rapid Fire Science Study Links:
Cannabinoids, Endocannabinoids, and Sleep (2020).(53:28)
Associations of Lifetime Psychedelic Use and Markers of Physical Health(1:09:30)
Secondary Source - https://www.psypost.org/2021/03/psychedelic-drug-users-tend-to-have-better-overall-physical-health-than-non-users-study-finds-60021
Today’s Game:
Check out the new game, called “guess which politician was high when they said this”. (1:22:15)
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Lovii Arora, Intro music by Buddha by Kontekst, Transition music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
We discuss a new research publication on cannabis hyperemesis from Dr. Ethan Russo and Nishi Whiteley, and a review article on serotonin receptors & psychedelics. This episode also offers the opportunity to learn the answers to important questions like, what are the potential risks and benefits of naturalistic mescaline use and what are non-psychedelic psychedelics? We also discuss indigenous populations and maple syrup. The show ends with a new game, Name that Drug! - Dr. Marcu reads a case report about an experimental drug treatment, while guests try to figure out if it was THC, psilocybin, LSD or a CBD extract.
Thank you to this episode’s sponsor Gooroo Music.
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Ethan Russo, MD
Nishi Whiteley
Del Potter, PhD
Nigam B. Arora, PhD
News and Popular Literature Links:
Naturalistic and Long Term Effects of Mescaline (2:57)
Are Non-psychedelic Psychedelic Compounds a “Bogus” Pipedream? and a $27 Million Grant Funding the Project (13:05)
Maple Syrup and Indigenous Populations (34:00)
Rapid Fire Science Study Links:
Serotonin and Brain Function: A tale of two receptors (41:30)
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation(57:00)
Today’s Game:
Name that drug! (1:23:15)
Credits:
Podcast editing by Joe Leonardo, Podcast mixing and mastering by Dylan Agajanian, Cover art by Robin Bordow, Intro music by Buddha by Kontekst, Transition Music by Gooroo Music. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
The group welcomes back guests Rod Kight and Jocelyn Sheltraw, international cannabis attorney and Director of Industry Relations at Headset respectively. We examine the recent legalization of cannabis in Mexico from several angles with Rod having recently relocated there to work on the ground and Jocelyn sharing projected first year sales. Other topics include the psychedelics patent race, potential uses for cannabis tax proceeds, an examination of the recent vaporizer shipping ban, and a look at cannabis product labeling regulations state by state. The show rounds out with a new game, “Guess which politician said this”. Tune in and see if you can guess the correct answer!
Thank you to this episode’s sponsor The GMP Collective.
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Jocelyn Sheltraw
Rod Kight, JD
Nigam B. Arora, PhD
News Links (2:21):
The Race is on to Patent Psychedelics - Profit margins leading the race, disappointment is in second place, and coming up in tie for last place, compassion and sustainability
South of the Border, Down Mexico Way - Is this where we will fall in love with a nation’s cannabis policies?
How Should Virginia (and other States) Spend Their Cannabis Profits?
From the Department of Idiotic and Worthless ideas - New law banning vaporizer shipments takes effect this year
Rapid Fire Science Study Links (52:30):
Kruger, D. J., Korach, N. J. & Kruger, J. S. Requirements for Cannabis Product Labeling by U.S. State. Cannabis Cannabinoid Res (2021) doi:10.1089/can.2020.0079.
Carhart-Harris, R. L. How do psychedelics work? Curr Opin Psychiatr32, 16–21 (2019).
Today’s Game (1:19:41):
“Guess which politician said this” - A new game for the group, can you guess the answer correctly?
Credits:
Podcast production by Dylan Agajanian, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
The group is joined by Nicole Howell, an attorney, psychonaut, and author in the psychedelics space. Nicole shares her experiences with helping to create new psychedelics legislation and policies with Jahan Marcu, PhD, Nigam B. Arora, PhD, Sara Ward, PhD, and David Vaillencourt, MSc. The discussion ranges from ways to incentivize private companies to invest in research, cannabis dinners in Thailand, research on predicting human responses to psychedelics, and data on the impact of cannabis use on outcomes in trauma patients. Be sure to stick around for a rousing game of “Guess the Psychedelic” hosted by Nigam B. Arora, PhD.
Thank you to Herbs for the Apocalypse for sponsoring this episode.
Nicole Howell’s article on Psychedelics and Capitalism
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Nicole Howell, JD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt, MSc
News Links:
As California Trips, so Trips the Nation. California bill would decrim psychedelics and expunge criminal records (2:27)
COMPASS to partner with Philadelphia’s USciences (17:40)
Thailand: Diners to try 140 cannabis-mixed dishes at exploratory fair (26:10)
Rapid Fire Science Study Links:
Predicting Responses to Psychedelics: A Prospective Study (34:50)
Preinjury Use of Marijuana and Outcomes in Trauma Patients(45:18)
Today’s Game:
“Guess the Psychedelic” - a 20 questions style game that tests your knowledge of psychedelics (57:55)
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supportingnthis episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
In this episode Amber Wise, PhD, joins the group discussion with Jahan Marcu, PhD, Nigam Arora, PhD, and Sara Jane Ward, PhD. We share our thoughts on federal agencies’ views regarding hemp use in employees and contractors, trends in psychedelics and mental health, and cannabis proficiency testing (aka PT). As well as a story about what it is like to use psychedelic drugs as a participant in a clinical study. For our peer reviewed research articles we discuss recent data on the stability of mushroom biomass under different storage conditions and cannabis use for creativity in business ventures. Our game this week will test your knowledge about cannabis cultivation.
Thank you to CReDO Science and Ethan Russo, MD for sponsoring this episode! https://credo-science.com
Episode’s Group:
Jahan Marcu, PhD (Moderator)
Amber Wise, PhD
Sara Jane Ward, Phd
Nigam B. Arora, PhD
News Links:
From the federal department of “Nice Try”! The DEA wants to know about your CBD and medical cannabis use pre-legalization (2:40)
Vogue - New Frontier Report and Data: Could the embrace of psychedelics lead to a mental-health revolution? (9:30)
What is it like to Smoke Salvia for Science (2nd article) (18:30)
Cannabis Proficiency Testing ; Industry Imperative for Quality & Consumer Safety (33:04)
Rapid Fire Science Study Links:
Head in the clouds? Cannabis users’ creativity in new venture ideation depends on their entrepreneurial passion and experience (For Discussion Puporses Only) (44:40)
Stability of psilocybin and its four analogs in the biomass of the psychotropic mushroom Psilocybe cubensis (59:30)
Today’s Game (01:10:36):
Test your cannabis cultivation trivia knowledge, with our new game called Room to Grow (01:10:36)
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting and naming this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Dr. Sara Jane Ward steps up to deliver one of the most unique episodes of HLI yet! Dr. Ward brings us two new and amazing members of the podcast crew, Dr. Deb Kimless and Dr. Del Potter. Dr. Kimless shares her experiences from working as a clinical cannabis researcher in the industry. Dr. Potter shares his views from his work in psychedelics drug R&D, informed by his extensive studies of psychedelics use among indigenous populations. Overall, a fun filled show exploring almost every aspect of the cannabis and psychedelics industries. A special thank you to the episode sponsor and friend of the show - Double Blind Magazine.
Episode’s Group:
Sara Jane Ward, PhD (Moderator)
Del Potter, PhD
Deb Kimless, MD
Jahan Marcu, PhD
Nigam B. Arora, PhD
News Links:
Exciting Landscapes in Cannabis Opportunities (2:35)
Cannabis For ... Everything? 23 Industries Seizing The $32B Market Opportunity - CB Insights Research
The Second Wave of Psychedelic Research in Europe (11:05)
https://icpr2020.net/europes-psychedelic-science-renaissance/
Quitting the Caffeine? (17:30)
Michael Pollan On Caffeine Addiction's Upside — And Ugly History : Shots - Health News : NPR
Do industry investments in research institutions create a conflict? (27:00)
https://www.statnews.com/2020/02/03/cash-from-cannabis-companies-creates-conflicted-researchers/
Rapid Fire Science Study Links:
The Effects of Cannabidiol-Based Sublingual Tablets on Diabetic Neuropathic Pain (36:30)
https://www.longdom.org/open-access/the-effects-of-cannabidiolbased-sublingual-tablets-on-diabetic-neuropathic-pain.pdf
Psychedelics Meet Artificial Intelligence. From ‘Molecules of Life’ To New Therapeutic Approaches, An Evolution Marked by the Advent of Artificial Intelligence: The cases of chronic pain and neuropathic disorders. (48:00)
https://www.sciencedirect.com/science/article/abs/pii/S1359644621000362?dgcid=rss_sd_all
Today’s Game (59:15):
Two truths and a lie; Dr. Ward discusses three stories about how people have been creatively sharing cannabis products during the pandemic. Can you sniff out the stinker? Cannabis stash n’ grabs? Gifting economies? Feeding edibles to Florida wildlife?
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
David Vaillencourt, MSc, CEO and Founder of the GMP Collective, hosts this episode featuring guest appearances by The Spock of Cannabis aka Darwin Millard, Jason Soroosh, MSPH, RD, Jahan Marcu, PhD, and Nigam B. Arora, PhD. David moderates a great discussion around veterinary medicine and CBD, FDA warning letters, ketamine assisted psychotherapy, exercise and chronic cannabis consumption, and the stability of cannabinoids under thermal degradation. Trichome fans won't want to miss out. This episode ends with a riveting game, which challenges panelists to figure out which two universities were involved in the first sale of cannabis via the internet.
Episode’s Group:
David Vaillencourt, MSc
Darwin Millard
Jason Soroosh, MSPH, RD
Jahan Marcu, PhD
Nigam B. Arora, PhD
News Links:
Michigan Law to Allow Veterinarians to Consult on Marijuana and CBD Therapy for Pets (4:20)
https://www.marijuanamoment.net/veterinarians-can-consult-on-marijuana-and-cbd-therapy-for-pets-under-michigan-governor-signed-bill/
FDA CBD Warning letters :A guide for deteriorating public health (14:00)
https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/nextl3vel-services-group-llc-dba-stuff-good-you-610446-12222020
https://mjbizdaily.com/ftc-cracks-down-on-deceptive-cbd-health-claims/
What It’s Like To Do Ketamine Assisted Psychotherapy (24:45)
https://doubleblindmag.com/what-its-like-to-do-ketamine-assisted-psychotherapy/
Rapid Fire Science Study Links:
Chronic Cannabis Consumption and Physical Exercise Performance in Healthy Adults: A systematic review (29:00)
https://link.springer.com/article/10.1186/s42238-020-00037-x
Thermal Stability of Cannabinoids in Dried Cannabis: A Kinetic Study (41:50)
https://doi.org/10.1007/s00216-020-03098-2
Today’s Game:
Two truths and a lie. David shares the story of how the internet of the 1970’s was used to sell cannabis. And the panelists have to guess the truth about which universities were involved. MIT? Stanford? Harvard? Berkeley? (51:45)
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition Music by K. LOUK. Outro music by Bensounds. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Founder and CEO of Credo Science Dr. Ethan Russo (also former Senior Medical Advisor at GW) shares his insights about the acquisition of GW Pharmaceuticals and discusses his experiences in cannabis drug development. Dr. Deb Kimless also joins the discussion to explore issues around psychedelics patents and the preservation of psychedelics producing fauna which ties into a book Dr. Russo authored 20 years ago about saving the rainforest (link below). Our scientific articles explore innovative cannabis research models and the safety of psychedelics in immunotherapy. At the end of the episode we put on our Good Manufacturing Practice hats, to play one of our favorite games.
Episode’s Group
Jahan Marcu, PhD
Ethan Russo, MD
Nigam B. Arora, PhD
Deb Kimless, MD
David Vaillencourt, MSc
Sarah Jane Ward, PhD (in spirit)
News Links:
COMPASS: We finally figured out how to make money off of hippie bean bags (3:14)
https://www.vice.com/en/article/93wmxv/can-a-company-patent-the-basic-components-of-psychedelic-therapy
JAZZ purchases GW for $7 Billion (11:40)
https://ir.gwpharm.com/news-releases/news-release-details/jazz-pharmaceuticals-acquire-gw-pharmaceuticals-plc-creating
Being Licked Out of Existence: Psychedelic Fauna Being Pushed to their Limits (29:20)
https://www.forbes.com/sites/davidcarpenter/2021/02/02/psychedelic-toads-pushed-to-the-limit-conservationists-urge-synthetic-5-meo-dmt-option/?sh=17eeed8d9615
Rapid Fire Science Study Links:
Cannabis and Health Research: Rapid Progress Requires Innovative Research Design (42:17)
https://pubmed.ncbi.nlm.nih.gov/31708066/
Is It Safe to Use Psychedelics During Cancer Immunotherapy? (58:49)
https://www.biorxiv.org/content/10.1101/2021.02.01.429102v1
Bonus:
Ethan Russo’s Novel about Saving the Rainforest
https://www.amazon.com/Last-Sorcerer-Echoes-Rainforest/dp/0789012707
Today’s Game (1:04:29):
“Where’s Vaillencourt?” a fun combination of Clue, Where’s Waldo, and 20 Questions. Where we guess the location, type of facility, and type of product HLI cast member David Vaillencourt has done his most recent GMP assessment. (01:09:32)
Credits:
Podcast production by Joe Leonardo, Cover art by Ivan Artucovich, Intro music by Buddha by Kontekst, Transition and Outro Music by K. LOUK. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Can we reimagine capitalism to incentivize companies that support research and sustainability? Are the CBD products out there safe and effective? Are there any differences between synthetic or natural terpenes? The Chief Public Affairs Officer from Berkeley Patients Group, Sebrina Fendrick, joins the group for this discussion. We celebrate Sabrina’s 6 year anniversary at Berkeley Patients Group by digesting new data about cooking with cannabis and treating autoimmune disorders with psychedelics. Finally we introduce the new and awkward game “Guess that Ethical Quandary”, where we discuss the ethics of the cannabis industry hijacking the online content of students that research cannabis.
Episode’s Group
Jahan Marcu, PhD
Sabrina Fendrick
Nigam B. Arora, PhD
Sarah Jane Ward, PhD
David Vaillencourt
News Links:
FDA News: Better data for better CBD (2:55)
https://www.fda.gov/news-events/fda-voices/better-data-better-understanding-use-and-safety-profile-cannabidiol-cbd-products?utm_medium=email&utm_source=govdelivery
How Tripping can Help us Reimagine Capitalism: What makes a good company, what makes a bad company? (15:31)
https://doubleblindmag.com/how-tripping-can-help-us-reimagine-capitalism-ahead-of-psychedelic-commercialization/
Synthetic vs Natural Chemicals: For example, Should states ban synthetic terpenes or terpenes “not found in nature”. What about psychedelics or cannabinoids (i.e., synthetic cannabidiol)? (30:48)
https://blogs.scientificamerican.com/guest-blog/natural-vs-synthetic-chemicals-is-a-gray-matter/
Rapid Fire Science Study Links:
So You Think You can Cook Pot?: Evaluating the knowledge of food safety and edible safety between users and non-users of cannabis edibles in British Columbia. (47:29)
https://circuit.bcit.ca/repository/islandora/object/repository%3A929
Psychedelics as a Novel Approach to Treating Autoimmune Conditions (55:32)
https://pubmed.ncbi.nlm.nih.gov/33035575/
Today’s Game (1:04:29):
“Guess that Ethical Quandary” from the case report “Something Stinks at this Law Office”. (1:05:45)
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst, Transition and Outro Music by Gooroo Music. Special thanks to Julian Amkraut for supporting this episode.
More at:
howtolaunchanindustry.com
marcu-arora.com
Founder and CEO of Via Innovations, Monica Vialpando, PhD, joins us for a critical look at the DEA potentially awarding more federal cannabis licenses. We explore the geriatric use of ayahuasca, followed by a look at the psychedelics decolonization movement. And we discuss the pros and cons of yoga and cannabis use. We travel through published scientific articles on meditation and music can influence drug experiences and perhaps, health outcomes. The episode concludes with a fun game, “Guess that Phony Drug Tabloid”.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sarah Jane Ward, PhD
Monica Vialpando, PhD
News Links:
DEA Widening Path for Medical Cannabis Research (2:32)
https://www.wsj.com/articles/dea-widens-path-for-medical-marijuana-research-11608235113
Trying Ayahuasca when You’re a Senior Citizen (10:00)
https://www.nytimes.com/2019/10/17/style/ayahuasca-senior-citizen.html
Inside the Movement to Decolonization Psychedelic Pharma (18:42)
https://neo.life/2020/10/inside-the-movement-to-decolonize-psychedelic-pharma/?fbclid=IwAR2uDt_f_FnR6Ktk5HTGT5mp9bhnmZLCEOpYo2RJZfvpzBMetgygWTqvlvs
Bringing Cannabis into Yoga Practice (30:45)
https://www.civilized.life/articles/how-to-bring-cannabis-into-your-yoga-practice/
Rapid Fire Science Study Links:
Meditation and Marijuana (1974) (48:22)
https://pubmed.ncbi.nlm.nih.gov/4808432/
Set and Setting: A Randomized Study of Different Musical Genres in Supporting Psychedelic Therapy (01:03:30)
https://pubs.acs.org/doi/10.1021/acsptsci.0c00187
Today’s Game (1:04:29):
Today the group plays a round of ‘Guess the Phony Drug Tabloid”, this is not an open-internet test. Which of today’s headlines is the real one:
“People Are More Likely to Try Drugs for the First Time During the Summer”
“Pet Owner Claims Microdosing his Cat Saved their Relationship”
Credits:
Podcast production by Joe Leonardo, Cover art by Saloni Sinha, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/. Special thanks to Julian Amkraut.
More at:
howtolaunchanindustry.com
marcu-arora.com
The group is joined by Tim Schlidt of Palo Santo, a thematic venture capital firm focused on the psychedelics industry. Together we explore a wide range of topics; the default mode network, basics of ayahuasca, the curious cases of jimson weed and imaginary cigarettes, as well as the pivotal role underground psychedelic labs played in laying the foundation for the industry. For Rapid Fire Science, we discuss two peer review articles, one focuses on a review of mescaline and the other on a psychiatric perspective of ayahuasca. The game ends with a rousing round of “Guess the Phony Drug Tabloid”, you won’t want to miss these headlines!
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Tim Schlidt
Sarah Jane Ward, PhD
News Links:
What is the Default Mode Network: Which part of the brain is talking to our brain when we are at rest? (1:42)?
https://psychedelicreview.com/what-is-the-default-mode-network/?fbclid=IwAR27Kwa_kl3TMZ80wcgp588XRDRVCXHwiodny8R57Gl-_44dpyYgt9_Va0o
What is Ayahuasca? (20:44)
https://doubleblindmag.com/what-is-ayahuasca-iowaska/?fbclid=IwAR1sOoFH46_p-IP5huxXzpZ0ZYAmXhrx4SuLq00N7a6TxONj0VebpURWvUQ
Jimson Weed Makes Users Smoke Imaginary Cigarettes (33:59)
http://plainfieldgardenclub.org/cgi-bin/p/awtp-showpic-pa.cgi?d=1754&s=96731
Acid Trip: Denver's Secret LSD Labs Fueled the Psychedelic Revolution (46:00)
https://www.westword.com/news/denvers-underground-lsd-labs-fueled-the-psychedelic-revolution-9644844
Rapid Fire Science Study Links:
Dark Classics in Chemical Neuroscience: Mescaline (56:40)
https://dx.doi.org/10.1021/acschemneuro.8b00215
How does Ayahuasca work from a Psychiatric Perspective? Pros and cons of the entheogenic therapy (Not Discussed Due to Time)
https://dx.doi.org/10.1002/hup.2728
Today’s Game (1:04:29):
Today the group plays a round of ‘Guess the Phony Drug Tabloid”. This is not an open-internet test. Which of Today’s headlines is the real one:
“Zookeeper Arrested for Dosing Penguins with LSD”
“Florida Sheriff Finds Crack between Buttocks”
“Jay-Z’s Cannabis Brand, Monogram, Launches With $50 Hand-Rolled Joints”
“Psilocybin is the next big thing in Functional Foods Industry”
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
The group is joined by the big minds from Psilera Bioscience, Jackie von Salm, PhD and Chris Witowski, PhD, to discuss everything from species of magic mushrooms, to the formation of a regulator’s cannabis association, to India’s Cannabis-Mania that is gripping Bollywood. Our science discussions focus on new psychoactive substances, and the pharmacology within the breadth of variety of the 2C class of compounds. The show ends with a rousing round of “Where’s Vaillencourt?” A 20 questions style game about cannabis GMP compliance and its geography. We’d also like to thank The GMP collective (https://www.gmpcollective.com) for sponsoring this episode.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
David Vaillencourt, MSc
Jackie von Salm, PhD
Chris Witowski, PhD
News Links:
Beyond Psilocybe Cubensis: 10 Magic Mushroom Species You Should Know About (3:18)
https://doubleblindmag.com/beyond-psilocybe-cubensis-10-magic-mushroom-strains-you-should-know-about/?fbclid=IwAR1H-lCuN-VJR-NgqK2NFBsrc_SJ6D4yVMdZGkw3Rhvbdf159kvnm7WLu3c
State Regulators Start “Cannabis Regulators Association” (11:56)
https://www.cann-ra.org/news-events/state-regulators-start-cannabis-regulators-association-dr6cc
History of the 2C designer Drug Class (24:25)
https://www.theverge.com/2015/7/15/8962743/all-smiles-the-history-of-the-2c-designer-drug-class
Weed Killer - Indian stoners face a moral crusade - Puritans fret that cannabis-crazed actors are corrupting the nation’s youth (35:00)
https://www.economist.com/asia/2020/10/22/indian-stoners-face-a-moral-crusade
Rapid Fire Science Study Links:
Acute Pharmacological Effects of 2C-B in Humans: An observational study (43:35)
https://dx.doi.org/10.3389/fphar.2018.00206
Long-lasting analgesic effect of the psychedelic drug changa : A case report (56:05)
https://dx.doi.org/10.1556/2054.2019.001
Today’s Game (1:10:40):
Today’s game is “Where’s Vaillencourt?”, a combination of 20 questions, Where’s Waldo, and Clue that focuses on friend of the show, David Vaillencourt’s journey through the world of cannabis focused GMP and its geography.
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee and Jackie von Salm, PhD, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro and transition music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
The group is joined by Joceyln Sheltraw, a social justice and cannabis enthusiast, and the Director of Regional Strategy and New Market Expansion for Headset. The show begins with a discussion on the role of the Marijuana Opportunity, Reinvestment, and Expungement (MORE) Act and Good Manufacturing Practices (GMPs) in cannabis business sustainability during the Biden administration followed by discussion of the release of DMT during orgasms. The group also examines balancing the introduction of commercial psychoactive substances in society with the socioeconomic burden of addiction; what impact will psychedelics have on addiction in society. The final news story looks at why administration forms matter for ketamine. The Rapid Fire Science segment reviews a clinical study on ketamine in multiple sclerosis and the paradoxical effects of LSD. Special thank you to Jason Soroosh for helping with this episode.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
David Vaillencourt, MSc
Jocelyn Sheltraw
News Links (1:43)):
Are cannabis stocks going to soar with Biden-Harris in the White House?
https://www.cnn.com/2020/11/09/investing/cannabis-stocks-election-biden-canopy-growth/index.html
Do Orgasms Release DMT?
https://doubleblindmag.com/do-orgasms-cause-the-release-of-dmt/
Can Psychedelics Therapy Ease the Socioeconomic Burden of Addiction
https://www.benzinga.com/markets/cannabis/20/10/18063553/can-psychedelic-therapy-ease-the-socioeconomic-burden-of-addiction
Why Route of Administration Matters for Ketamine
https://www.principiumpsychiatry.com/iv-vs-oral-vs-intramuscular-vs-intranasal-ketamine-why-route-matters
Rapid Fire Science Study Links (32:00):
Pilot randomized active-placebo-controlled trial of low-dose ketamine for the treatment of multiple sclerosis–related fatigue https://dx.doi.org/10.1177/1352458520936226
The paradoxical psychological effects of lysergic acid diethylamide (LSD)
https://dx.doi.org/10.1017/s0033291715002901
Today’s Game (51:55):
Today the group plays a round of ‘Guess the Phony Drug Tabloid”, this is not an open-internet test. Today’s headlines are:
Psychedelics are back, man
Inhaling Cannabis Linked to Staying Alive, Study Shows
Move Over, Pot: Psychedelics Companies Are About to Go Public
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
The group discusses the dichotomy between patenting psychedelics compounds and promoting free and open research, the complexities of South American cannabis in Europe, and the 12,000 year old relationship between humans and psychedelics. Rapid fire science looks at the side by side comparison of two hallucinogenic substances and how well various cannabinoids permeate the skin. To conclude the group plays the 20 questions style game, “Guess the Psychedelics or Cannabis Research Institute”.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt, MSc
Rod Kight, JD
News Links (2:10):
Clash of the Psychedelics - As COMPASS Pathways continues its attempts to build a psychedelic monopoly, Usona Institute keeps publishing open research
https://www.psymposia.com/magazine/compass-psychedelic-psilocybin-patents-usona-open-science/?fbclid=IwAR3xYxCk0-gu6EaXZ8YRMHypfUA-C-pahBLAy8CCSB76Q8woTuFpdUkEfU8
Cheese Quake Now Available in Germany via Uruguay
https://mjbizdaily.com/uruguay-grown-medical-cannabis-available-in-germany-for-first-time/#:~:text=Medical%20cannabis%20flower%20grown%20in,market%20for%20the%20first%20time.&text=The%20German%20subsidiary%20of%20Nanaimo,30.
The Complete(Abridged) History of Psychedelics
https://www.psytech.biz/history-of-psychedelics-2/
Rapid Fire Science Study Links (35:03):
Double-blind Comparison of the Two Hallucinogens Psilocybin and Dextromethorphan: Effects on cognition psychopharmacology
https://dx.doi.org/10.1007/s00213-018-4981-x
Human Skin Permeation of Δ8‐tetrahydrocannabinol, Cannabidiol, and Cannabinol
https://dx.doi.org/10.1211/0022357022791
Today’s Game (53:30):
“Guess the Psychedelics or Cannabis Research Institute” is a 20 questions style journey to find out which research institute or core caught Nigam B. Arora’s attention.
Credits:
Podcast production by Joe Leonardo, Cover art by Selina Lee, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
The group discusses hallucinogenic beer with a side of clinical candy flipping and other concepts like use of psychedelic experiences to replace prison sentences and how MDMA may act as a glue for marriages and relationships. Rapid fire science examines the promiscuity of psychedelics and the potential applications of CBD analogs. To end, the group plays the 20 questions style game, “Where’s Vaillencourt?”.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt, MSc
(Inspired by Del Potter, PhD)
News Links (1:42):
NYC Psychotherapist Charley Wininger Says MDMA Is The ‘Glue’ of His Marriage
https://www.forbes.com/sites/amandasiebert/2020/10/14/nyc-psychotherapist-charley-wininger-says-mdma-is-the-glue-of-his-marriage/?sh=6f6c889776a1
MindMed Announces First-Ever Clinical Trial Combining MDMA and LSD
https://www.prnewswire.com/news-releases/mindmed-announces-first-ever-clinical-trial-combining-mdma-and-lsd-301117559.html
Altering Prisoners’ Sense of Time: The moral regression of a futuristic technology
http://blogs.kentlaw.iit.edu/islat/tag/time-distortion-drugs/
A History of Hallucinogenic Beers
https://oct.co/essays/history-hallucinogenic-beers-magic-mushrooms-henbane?fbclid=IwAR0ERrn3WbFHVdXWDvJ1azcY5gxF1YQSsOuRu3OSab6Y8k6_jOxoogpHpgQ
Psychedelic Exceptionalism
https://doubleblindmag.com/psychedelic-exceptionalism/?fbclid=IwAR3pOADv0TJrMPT8z8ZAxHTnhlptmuLdEULTo2YuOSFX0AH70nKGX37kZy4
Rapid Fire Science Study Links (43:06):
Polypharmacology or “Pharmacological Promiscuity” In Psychedelic Research: What are we missing?
https://dx.doi.org/10.1021/acschemneuro.0c00614
Cannabidiolic Acid Methyl Ester: A stable synthetic analogue of cannabidiolic acid, can produce 5‐HT1A receptor‐mediated suppression of nausea and anxiety in rats
https://dx.doi.org/10.1111/bph.14073
Today’s Game (56:10):
Today’s game is “Where’s Vaillencourt?”, a combination of 20 questions, Where’s Waldo, and Clue that focuses on, friend of the show, David Vaillencourt’s journey through the world of cannabis focused GMP.
Credits:
Podcast production by Joe Leonardo, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
The group discusses resetting the brain, psychedelics terminology, ketamine infusions, research on the therapeutic usefulness of bad trips, and updates in the field of cannabis product safety. Special guest Kim Napoli, JD, joins HLI to bring valuable insights to the table. The show ends with a 20 questions style game, Guess the Cannabinoid.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
David Vaillencourt, MSc
Kim Napoli, JD
News Links (1:29):
Magic Mushrooms Can Reset Depressed Brain
https://www.bbc.com/news/health-41608984
Get Your Cannabis Card and an IV Solution of Ketamine at this Chicago Office
https://www.neuromedici.com
Cannabis Regulatory Patchwork Leaves Holes in Safety Standards
https://www.salon.com/2020/10/18/in-the-cannabis-patch-a-patchwork-of-safety-standards-and-in-some-cases-none-at-all_partner/
Rapid Fire Science Study Links (24:04):
Good Manufacturing Practice Compliance is not Optional
https://dx.doi.org/10.1016/b978-0-12-819512-3.00004-3
Making “Bad Trips” Good: How users of psychedelics narratively transform challenging trips into valuable experiences
https://dx.doi.org/10.1016/j.drugpo.2020.102997
Today’s Game (51:54):
Today’s game is Guess the Cannabinoid. A twenty questions style game, where the group asks yes or no questions to determine what the cannabinoid is. Is it from a plant, made in a lab, or purified from the brain of a mammal?
Credits:
Podcast production by Joe Leonardo, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
News articles focusing on DEA intimidation related to delta-8 THC, engineering yeast to make psychedelics, and psychedelics use and depression. Scientific publications on the impact of naturalistic psychedelics on drug use and consumer understanding of cannabis labels. The show ends with a game that tests your knowledge of hemp in early warfare.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
Jason Soroosh, MSPH, RD
News Links (1:50):
Delta-8 THC or Delta-wait-a-minute THC?!
https://abovethelaw.com/2020/09/the-dea-interim-final-rule-a-menace-to-the-burgeoning-delta-8-thc-industry/
Yeast Making Psychedelics: Biotech breakthrough or does nature do it better?
https://massivesci.com/articles/psilocybin-yeast-magic-mushrooms-psychedelics/
PopScience: Depression and suicidal ideation reduced after psychedelic usage
https://bigthink.com/mind-brain/psychedelics-depression
Rapid Fire Science Study Links (34:18):
Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An online survey https://dx.doi.org/10.3389/fpsyt.2019.00955
Consumer Use and Understanding of Labelling Information on Edible Marijuana Products Sold for Recreational Use in the States of Colorado and Washington
https://dx.doi.org/10.1016/j.drugpo.2017.01.006
Today’s Game (58:01):
In today’s game the group is challenged with a short story and have to use their critical thinking skills to suss out the incorrect or unsupported statement out of the case presented. This week the group is challenged with three potential facts about the role of hemp in early warfare.
Credits:
Podcast production by Joe Leonardo, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
An elephant is dosed with CBD oil, a look at who’s who in raising psychedelic advocacy funding, Republicans blast Harris over pot record, Canadian cannabis use is associated with reduction in IV opioid use, and cannabis use disorder improves inpatient survival. Our show ends with a game that tests your knowledge on cannabis hyperemesis syndrome.
Episode’s Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt, MSc
News Links (1:30):
Elephant Will Be Given CBD To Treat Stress After Death Of Companion, Zoo Says
https://www.marijuanamoment.net/elephant-will-be-given-cbd-to-treat-stress-after-death-of-companion-zoo-says/
Congressman Raising Money To Legalize Psychedelic Mushroom Therapy
https://www.marijuanamoment.net/congressman-raising-money-to-legalize-psychedelic-mushroom-therapy/
Republicans Blasting Democrats on Cannabis Policy
https://www.marijuanamoment.net/another-republican-convention-speaker-slams-marijuana-policies-from-democrats/
Rapid Fire Science Study Links (31:10):
What is in Canadian Cannabis? New data shows associated reductions in IV opioid use with cannabis use
https://pubmed.ncbi.nlm.nih.gov/32816538/
Cannabis Use Disorder Associated with Decrease Chance of Death in Hospital; Cannabis use associated with reduced hospital deaths due to heart failure
https://pubmed.ncbi.nlm.nih.gov/32766001/
Today’s Game (59:41):
Truth or Fiction (aka 2 out of 3) - This is a game where the group is challenged with a short story and have to use their critical thinking skills to suss out the incorrect or unsupported statement out of the case presented. This week the group is challenged with three potential facts about a recent article regarding cannabis hyperemesis syndrome (CHS) and cyclic vomiting syndrome (CVS).
Credits:
Podcast production by Joe Leonardo, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
Join the group for a discussion about a study on CBD withdrawal as well as the latest research from regulators and public health experts on the cannabis edible landscape. We provide commentary on the recent coverage of DEA delays, cannabis product recalls, new guidance for psychedelic healing centers, and a dive into recent issues facing State hemp programs. This episode ends with a game that tests your knowledge about CBD and pharmacists.
News Links (1:30):
Cannabis Industry News - Who pre-licked my pre-roll; a cautionary tale
https://www.leafly.com/news/industry/hey-who-pre-licked-my-pre-roll-a-cautionary-tale-in-the-time-of-covid-19
Election Coverage and Issues - DEA’s Marijuana Delays Are Costing Americans Jobs, Bipartisan Lawmakers Say
https://www.marijuanamoment.net/deas-marijuana-delays-are-costing-americans-jobs-bipartisan-lawmakers-say/
Psychedelic Healing - Advocates Unveil Guide For Psychedelic Healing Ceremonies They Hope To Legalize In Oakland
https://www.marijuanamoment.net/advocates-unveil-guide-for-psychedelic-healing-ceremonies-they-hope-to-legalize-in-oakland/
https://www.marijuanamoment.net/oakland-officials-decriminalize-psychedelics-and-say-theyll-work-to-legalize-sales-next/
State Hemp Programs are on the Fritz
https://therichardrosereport.com/new-york-ditches-hemp-program/
https://www.westword.com/marijuana/colorado-must-rework-industrial-hemp-laws-for-usda-approval-11775010
Rapid Fire Science Study Links (39:23):
The ECP Landscape (Edible Cannabis Products)
https://dx.doi.org/10.1080/10408398.2020.1793099
Does CBD withdrawal exist? And why do we care?
https://dx.doi.org/10.1016/j.yebeh.2020.106938
Today’s Game (53:03):
Truth or Fiction (aka 2 out of 3) - This is a game where the group is challenged with a story and have to use their critical thinking skills to suss out the incorrect or unsupported statement out of the case presented. This week the group is challenged with three potential facts about a recent article regarding pharmacists and CBD.
Credits:
Podcast production by Joe Leonardo, Intro music by Buddha by Kontekst https://soundcloud.com/kontekstmusic, Outro music by: Music courtesy of Bensound: http://www.bensound.com/
More at:
howtolaunchanindustry.com
marcu-arora.com
Join the group for a discussion about FDA guidance for cannabis research, updates on new psilocybin delivery forms, as well as research into cannabis and its impact on fitness. Don’t miss the end of the episode, when we play the game “Guess the Psychedelic” with a special surprise guest.
Group
Jahan Marcu, PhD
Nigam B. Arora, PhD
Sara Jane Ward, PhD
David Vaillencourt
Brett Greene (special guest)
News Links (1:30):
FDA guidance for cannabis clinical trials:
https://www.fda.gov/media/140319/download
New company to put psilocybin on dissolvable sublingual strips to help treat depression
https://www.leafly.com/news/health/psilocybin-dissolvable-sublingual-strips-treat-depression
Rapid Fire Science Study Links (20:40):
CBD a safe treatment for cannabis use disorders, study finds
http://www.upi.com/Health_News/2020/07/28/CBD-a-safe-treatment-for-cannabis-use-disorders-study-finds/9301595951372/
Cannabis has no negative impact on fitness in older adults
https://pubmed.ncbi.nlm.nih.gov/32553024/
Game Segment (38:50):
Guess the Psychedelic - a 20 questions style game that tests your knowledge of psychedelics.
More at:
howtolaunchanindustry.com
marcu-arora.com