Innovations In Medicine: Recent Episodes

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Distinguished researchers discuss their latest findings in science and biotechnology, offering an intriguing glimpse of medicine's future.  Sponsored by:

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Piotr Kowalski, PhD

mRNA technology may have a potential role in several areas of gene editing. But are there any barriers to its application in clinical practice? Dr. Piotr Kowalski from the University College Cork explores mRNA technology in gene editing.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Musaddiq Khan

Clinical data continues to emerge on mRNA therapeutics and their applications. What do we need to know about this data, and are there any barriers to the broader application of these therapeutics? Dr. Charles Turck is joined by Musaddiq Khan, the Vice President of Therapeutic Area Solutions in the Customer Value Team at Medable, to dive into clinical trials for mRNA therapeutics.

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Host: Jennifer Caudle, DO

Guest: Francesca Taraballi, PhD

Guest: John J. Russell, MD

As mRNA therapeutics continue to emerge, what do our patients know about them? Joining Dr. Jennifer Caudle to explore knowledge gaps and discuss tactics to educate patients are Drs. John Russell and Francesca Taraballi.

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Guest: John P. Cooke, MD, PhD

What are some of the biggest challenges in regenerative medicine, and can mRNA therapeutics help us combat them? Dr. John Cooke from the Houston Methodist DeBakey Heart and Vascular Center explores these obstacles and shares how we can overcome them with potential mRNA therapeutics.

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Guest: Hyunjoon Kim, PhD

New mRNA therapeutics are on the horizon for patients with autoimmune diseases. What kind of impact might these therapeutics have? To answer this question, Dr. Hyunjoon Kim, Assistant Professor in the Department of Pharmaceutical Chemistry at the University of Kansas, joins us to explore these new therapeutics.

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Guest: Ahmed Zayed Obeidat, MD, PhD

The developments of mRNA therapeutics may change the way we treat neurodegenerative diseases. Here to provide insight on the role of these therapeutics and share what’s on the horizon is Dr. Ahmed Obeidat, Assistant Professor in the Department of Neurology at the Medical College of Wisconsin.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: John P. Cooke, MD, PhD

What do we need to know about the potential utility of mRNA therapeutics in regenerative medicine? Joining Dr. Charles Turck to discuss mRNA medicine’s potential impact on tissue engineering and targeted tissue restoration is Dr. John Cooke, Medical Director of the RNA Therapeutics Program in the Houston Methodist DeBakey Heart and Vascular Center.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Ahmed Zayed Obeidat, MD, PhD

Multiple sclerosis (MS) is a disabling disease that has challenged clinicians for decades. But developments in our understanding of the Epstein-Barr virus and emerging mRNA therapeutics may help us determine the root cause of MS—and develop a preventative treatment for it.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Laila Woc-Colburn, MD, DTM&H, FACP, FIDSA

Guest: John P. Cooke, MD, PhD

The COVID-19 pandemic has led to patient disparities that have impacted the development and delivery of mRNA medicine. What do we need to know about these obstacles, and how can we overcome them? Dr. Charles Turck is joined by Drs. John P. Cooke and Laila Woc-Colburn to explore barriers to access.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Piotr Kowalski, PhD

As myths and misconceptions continue to arise regarding mRNA technology, what can we do to address them? Joining Dr. Charles Turck to explore some of these misconceptions is Dr. Piotr Kowalski from the University of College Cork in Ireland.

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Guest: Jianxun Song, PhD

Several mRNA therapeutics are in development for cancer immunotherapy. What do we need to know about them? Dr. Jianxun (Jim) Song explores mRNA technology’s impact on antigen-specific T cells and immuno-oncology.

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Guest: Francesca Taraballi, PhD

As mRNA therapeutics continue to evolve, what do we know about its potential in the treatment of infectious diseases? Dr. Francesca Taraballi from the Center for Musculoskeletal Regeneration at the Houston Methodist Hospital explores emerging mRNA therapeutics.

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Host: John J. Russell, MD

Guest: John P. Cooke, MD, PhD

mRNA was first discovered in the 1980s, and it wasn’t until recently that mRNA technology entered the spotlight. But how did we get to this point, and where do we go from here? Discover this and more with Dr. John Russell and Dr. John Cooke, Director of the Center for Cardiovascular Regeneration and Medical Director of the RNA Therapeutics Program in the Houston Methodist DeBakey Heart and Vascular Center.

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Guest: John P. Cooke, MD, PhD

Message RNA (mRNA) is a copy of a gene within DNA. And based on how mRNA functions in the body, how can we leverage it to help protect us against infectious disease? Explore this and more with Dr. John P. Cooke, Director of the Center for Cardiovascular Regeneration and Medical Director of the RNA Therapeutics Program in the Houston Methodist DeBakey Heart and Vascular Center.

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Host: Jerome Lisk, MD

Guest: Mark Mintz, MD

Recent developments in artificial intelligence (AI) technology have shown to aid with neurological disease diagnosis, risk stratification, treatment response, and more. So what are the newest AI applications? And perhaps even more importantly, what’s to come in the future? To find out the answer to these and other key questions, Dr. Jerome Lisk speaks with Dr. Mark Mintz, Chief Medical Officer and Founder of NeurAbilities Healthcare, to discuss emerging AI tools in the field of neurology.

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Host: Peter Buch, MD, FACG, AGAF, FACP

Guest: Brennan Spiegel, MD, MSHS

Let’s escape our busy day for a moment to imagine the future of gastroenterology and to ask ourselves: How can technology make us better clinicians? Explore that very question with Drs. Peter Buch and Brennan Spiegel as they discuss the latest advances in artificial intelligence and virtual reality that are aiding both clinical practice and research efforts.

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Host: Neilanjan Nandi, MD

Guest: Peter D. Higgins, MDm PhD

What's on the horizon for the management of inflammatory bowel disease? To share some of the latest clinical trial updates, Dr. Neil Nandi is joined by Dr. Peter Higgins from the University of Michigan to explore some of the latest developments in early detection tools and treatment strategies for patients with IBD.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Chris Beyrer, MD, MPH

Amid the ongoing COVID-19 pandemic, countries in Sub-Saharan Africa are also facing high rates of HIV and AIDS prevalence. But after the success of the mRNA COVID-19 vaccines, could an mRNA vaccine for HIV/AIDS be on the horizon? Here to explore emerging research and the potential role that mRNA technology might have in battling this global epidemic is Dr. Chris Beyrer, a Professor of Epidemiology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Animesh Ray, PhD

Getting ahead of the next pandemic may be possible thanks to deep machine learning’s ability to predict the structure of antibodies. And while that may sound like science fiction, this technology is currently being studied, which is why Dr. Animesh Ray from the Keck Graduate Institute joins Dr. Charles Turck to provide insight on where the research currently lies and what we have to look forward to.

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Host: Alan S. Brown, MD, FACC, FAHA, FNLA

Guest: Sheng Xu, PhD

Sheng Xu, Professor of Nanoengineering, Bioengineering, Computer and Electrical Engineering at the UC San Diego Jacobs School of Engineering, meets with Dr. Alan Brown to discuss his innovative technology to change the way we predict cardiovascular risks.

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Host: Michael Greenberg, MD

Guest: Sam Polesie, PhD

Can technology play a role in assessing melanoma? Dr. Michael Greenberg discusses the use of artificial intelligence in dermatology with Dr. Sam Polesie, a specialist physician in the Department of Dermatology and Venereology at the Sahlgrenska University Hospital in Gothenburg, Sweden.

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Host: Carol Wysham, MD

Guest: Irl Hirsch, MD, MACP

How is technology like continuous glucose monitors impacting the way we care for patients with diabetes, especially amid the COVID-19 pandemic? To learn more about the technological advancements in diabetes care, Dr. Carol Wysham speaks with Dr. Irl Hirsch, a Professor in Diabetes Treatment and Teaching Chair at the University of Washington School of Medicine in Seattle, Washington.

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Host: David Weisman, MD

Guest: Mijail D Serruya MD,PhD

Thousands of Americans live with the debilitating aftereffects of stroke, such as arm and communication problems. This makes technological developments like brain-computer interfaces absolutely critical for stroke survivors, but some questions are beginning to arise regarding the ethics of this technology. So in order for us to fully pursue this advancement, it’s important that we address those ethical concerns, as Dr. Mijail Serruya explains.

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Host: Matthew Sorrentino, MD

Guest: Jennifer N. Avari Silva, MD

Each year, more than 75 thousand cardiac ablation procedures are performed in the United States alone. Could something straight out of a science-fiction movie like holograms help improve physician accuracy and reduce the complications typically associated with this procedure? Talk a walk on the futuristic side of medicine with Dr. Matthew Sorrentino and Dr. Jennifer Silva, who co-led a team that tested a unique headset using mixed reality technology during cardiac ablation procedures at St. Louis Children’s Hospital.

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Looking to the future of healthcare, Mark Masselli and Margaret Flinter speak with Dr. Rasu Shrestha on the two things that are needed to truly transform the system: design thinking and a culture of innovation.

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Host: Matt Birnholz, MD

Psychiatry gets a bad rep for being one of the more "technophobic" fields in clinical medicine. This negative association stems in part to the difficulty in tracking changes in mood, cognition, and certain behaviors over time. But there is a growing contingency of psychiatric clinicians who are bringing technology into this specialty to help propel standards in mental health care.

Dr. Adam Kaplin, Assistant Professor of Psychiatry at Johns Hopkins School of Medicine and Principle Psyciatric Consultant to the Johns Hopkins Multiple Sclerosis and Transverse Myelitis Centers of Excellence, joins Dr. Jennifer Caudle to discuss ways in which technological innovations can enhance psychiatric care and decrease stigma surrounding mental illness.

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Host: Matt Birnholz, MD

Guest: Ronald J. Wapner, MD

Innovations in medical genetics are changing the practice of obstetrics and gynecology. With advancing knowledge of underlying genetic predispositions, doctors can provide more precisioned care plans for patients in women's health centers.

Dr. Matt Birnholz talks with Dr. Ronald J Wapner, Professor of Obstetrics and Gynecology and Director of Reproductive Genetics at Columbia University, about how the ever-changing field of medical genetics is revolutionizing OB/GYN treatment options and patient care.

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Host: Paul Raeburn

Guest: Babak Parviz, PhD

Paul Raeburn interviews Dr. Babak Parvis of the University of Washington about putting computers on contact lens. Pie in the Sky? Not if this scientist has anything to do with it.