Dr Russell Talks Patho: Recent Episodes
drrusselltalkspatho
Welcome to Dr Russell Talks Patho, where we will discuss pathophysiology and help you gain a better understanding of how the body functions in a disease state.
Music: ”One Little Triumph” by Blue Dot Session https://freemusicarchive.org/music/Blue_Dot_Sessions
This episode covers how changes in water and electrolytes affect cellular function. We discuss sodium, potassium and calcium irregularities as well as respiratory and metabolic acidosis/alkalosis.
This episode discusses the various was cells can be damaged, such as hypoxic injury, chemical injury and blunt force trauma. It then explains the various ways cells will respond or adapt that that damage/stressor like atrophy or hypertrophy, and finally we talk about cell death, apotosis, and necrosis.
This episode covers aspiration, acute respiratory distress syndrome, atelectasis, pneumothorax, pleura effusions, asthma, chronic bronchitis and emphysema.
This episode covers, endocardial (valvular), conduction (ECG), myocardial (myopathies), pericardial (effusions) disorders and shock. Many of these are a result of cardiovascular/heart disease and complications of acute coronary syndromes. These include:
- Endocardial Disorders: Valvular Stenosis/Regurgitation, Infective Endocarditis/Rheumatic Heart Disease, Dysrhythmias, (PAC, SVT, Atrial Flutter, AFib, PVC, VT, VFib, Heart blocks/Bundle Branch blocks), Heart Failure (L/R, Systolic/Diastolic),
- Cardiomyopathies: dilated, restrictive and hypertrophic.
- Pericardial Disorders: acute/chronic pericarditis, pericardial effusion, cardiac tamponade, circulatory shock and pulsus paradoxus.
- Shock: Cardiogenic, Hypovolemic/Hemorrhagic, Neurogenic, Anaphylactic, Septic and complications of shock (ARDS, renal failure, DIC).
This episode covers polycythemia and anemias as well as hyper and hypo coagulability states.
This episode introduces the processes of perfusion, thrombi and emboli (blood clot) formation as well as infarcts. On the arterial side, we dive into the pathogenesis of peripheral artery disease, arteriosclerosis and atherosclerosis. Clinical manifestations covered include: carotid & coronary artery disease, aneurysm, arterial dissection (dissecting aneurysm) and treatments discussed include angiography and angioplasty. Special attention is given to coronary artery disease, stable angina, and acute coronary syndromes like myocardial infarction (heart attack). On the venous side we discuss chronic venous insufficiency, venous stasis ulcers, varicose veins. esophageal varices, portal hypertension, hemorrhoids, and deep vein thrombosis. Systemic vascular disorders such as hypertension, orthostatic hypotension and discussed briefly.
This episode discusses Type 1 and Type 2 Diabetes Mellitus and compares their pathophysiology with Diabetes Insipidus.
This episode discusses motor disorders such as Parkinson Disease, Huntington Disease, Multiple Sclerosis and ALS. The end of the episode discusses the different types of seizures.
This episode covers a review of cerebral blood flow, events that follow ischemic and hypoxic brain injury and the etiology, pathogenesis and clinical manifestations of strokes and hemorrhages.
This episode looks at the major types of nociceptors, pain transduction, transmission and pain perception. We also discuss pain modulation, nociceptive/neuropathic pain and headaches. Then we discuss how the body maintains body temperature as well as the extremes of hyperthermia and hypothermia.
This episode covers the etiology, pathogenesis, diagnosis and treatment of both upper and lower respiratory infections.
This episode describes the series of events that allows microbial pathogens to produce infectious disease in humans.
This episode defines neoplasm and discusses concepts related to the development of malignant tumors. Topics include the cell cycle in both normal and malignant cells, including an over view of proto-oncogenes, oncogenes and tumor suppressor genes. We will look at the etiology, pathogenesis, manifestations and treatments of cancer.
This episode covers some of the historical background and general concepts of stress. We will discuss the stress response and how stress affects personality, coping and can lead to illness.
This episode covers the language used in and the conceptual basis for pathophysiology, including: the characteristics of health and illness, risk factors, etiology and pathogenesis of a disease, clinical manifestations and how lifespan, nutrition and genetics affect health. Chronic disease is discussed as well as an overview of pathophysiologic mechanisms that can result in disease. The study of epidemiology is introduced.