The DASON Digest features engaging conversations with experts in infectious diseases and antimicrobial stewardship covering a variety of topics. New episodes of the Digest are published every other Friday. Subscribe to follow along with our latest content.
For more information about DASON, please visit https://dason.medicine.duke.edu.
Episode NotesIn this episode, Dr. Jeannette Bouchard discusses a newly published article in JAMA about the use of piperacillin-tazobactam and cefepime in sepsis. This episode also ties into a previous episode (#74) and we would recommend listening to both episodes!
The article reviewed in this episode can be found here: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2818278
For more information about DASON, please visit: https://dason.medicine.duke.edu/
Episode NotesIn this episode, University of Kentucky Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, review a recently published article evaluating the impact of the implementation of rapid blood culture identification technology and stewardship intervention on treatment of blood cultures contaminated with coagulase-negative staphylococci. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/8/ofad416/7233915
For more information about DASON, please visit: https://dason.medicine.duke.edu/
Episode NotesIn this episode, University of Kentucky PGY2 Infectious Diseases Pharmacy Residents, Will Harris and Tyler Pitcock, discuss the recently published article evaluating the efficacy of the clinical decision tool, PEN-FAST, in de-labeling patients with reported penicillin allergies with one of the authors and Duke University Hospital Infectious Diseases Physicians, Dr. Nick Turner. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37459086/
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Episode NotesIn this episode, Duke University Hospital Infectious Diseases Pharmacist Dr. Rebekah Wrenn and her resident, Amy Mackowiak, review Dr. Wrenn's recently published article evaluating the impact of default duration elimination on exposure to fluoroquinolone therapy. The article reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38347810/
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Episode NotesIn this episode of the DASON Digest Podcast, one of our DASON Clinical Pharmacist Liaisons, Dr. Melissa Johnson, talks with Dr. Jim Lewis, ID Clinical Pharmacy Coordinator and Adjunct Associate Professor at Oregon Health & Science University Departments of Pharmacy and ID in Portland, Oregon. The material reviewed in today's podcast can be found here: https://clsi.org/standards/products/microbiology/documents/m100/
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Episode NotesIn this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about how to incorporate adverse event feedback into antibiotic stewardship. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415083/
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Episode NotesIn this episode, DASON Clinical Pharmacist Liaisons Drs. Jeannette Bouchard and Libby Dodds-Ashley walk us through the details of a recent article published in ASHE to assess the impact of a clinical decision support survey to improve GI Panel ordering appropriateness at a VA. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38415090/
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Episode NotesIn this episode of the DASON Digest podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the use of active versus passive methods of responding to rapid diagnostic blood culture results. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/36483427/
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Episode NotesIn this episode, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard is joined by Dr. Kevin Garey, an adjunct professor at the University of Texas School of Public Health and senior author of the reviewed article. They walk us through the details of the microbiome effects oral omadacycline has versus oral vancomycin and what this might mean for the future of the treatment for C. difficile infections. The materials reviewed in today's episode can be found here: https://pubmed.ncbi.nlm.nih.gov/38051631/ and https://pubmed.ncbi.nlm.nih.gov/22563022/
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Episode NotesIn this episode, DASON Clinical Pharmacist Liaisons Drs. Melissa Johnson and Jeannette Bouchard discuss an article from ASHE on high-dose oral beta-lactam definitive therapy compared to fluoroquinolone or trimethoprim-sulfamethoxazole oral therapy for bacteremia secondary to a urinary tract infection. The article reviewed can be found here: https://pubmed.ncbi.nlm.nih.gov/37771747/
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Episode NotesIn this episode, Dr. April Dyer, one of our DASON Clinical Pharmacist Liaisons, talks to us about source specific order sets leading to improved empiric therapy in the ED in a 200 bed hospital. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad677/7491622#
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Episode NotesIn this episode, Drs. Bouchard, Dodds Ashley, and Perez review a large study tackling inappropriate antimicrobial use in the outpatient setting. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad585/7439469
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Episode NotesIn this episode, Drs. Libby Dodds Ashley and Jeannette Bouchard, two of our DASON Clinical Pharmacists, talk to us about bringing and end to VAP. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37888914/
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Episode NotesThis week we would like to use the feed to share a great episode of Sara Dong's podcast "Febrile." Members of our DASON team and the Society for Healthcare Epidemiology of America's antimicrobial stewardship committee celebrate antibiotic awareness week by discussing stewardship teams and an example case.
Episode NotesIn this episode, Dr. April Dyer, one of the DASON Clinical Pharmacists, talks about cefepime vs piperacillin-tazobactam in adults hospitalized with acute infection. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37837651/
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Episode NotesDrs. Perez, Hillenbrand and Mourad do a deep dive on how to best apply one of our most common stewardship tools. The article reviewed in this episode can be found here: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciad467/7240295
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Episode NotesIn this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Jeannette Bouchard talks to us about clinical risk scores to improve empiric antimicrobial selection for outpatient complicated urinary tract infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/8/ofad319/7198038#413122181
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Episode NotesIn this episode, Dr. Rey Perez chats with Drs. Rebekah Moehring and Libby Dodds Ashley about work done by the University of Pittsburgh using a weighted lottery to equitably allocate scarce supply of COVID-19 monoclonal antibody to patients. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37656472/
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Episode NotesIn this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. Angelina Davis talks to us about the early discontinuation of antibiotics in patients admitted with clinically suspected serious infection but negative cultures. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37449298/
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Episode Notes In this episode of the DASON Digest Podcast, DASON Clinical Pharmacist Liaison Dr. April Dyer talks to us about improving the efficiency of antimicrobial stewardship action in acute care facilities. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad412/7234482
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Episode Notes Dr. Rey Perez chats with our newest DASON Clinical Pharmacist Liaison, Dr. Jeannette Bouchard, about the epidemiology of gram negative blood stream infections. The article reviewed in this episode can be found here: https://academic.oup.com/ofid/article/10/7/ofad265/7175984
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Episode Notes Dr. Melissa Johnson from DASON talks to us about removing incorrect penicillin allergy labels. There are lots of supplemental materials for this episode, and they can all be viewed on the episode's page on our website: https://dason.medicine.duke.edu/blog/rx-success-tackling-penicillin-allergy-de-labelling-our-hospitals
The main article discussed today is: https://pubmed.ncbi.nlm.nih.gov/37354996/
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Episode Notes In this episode, Dr. Angelina Davis talks to us about the use of clindamycin + vancomycin vs. linezolid for the treatment of necrotizing soft tissue infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37351452/
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Episode Notes For this episode, Drs. Libby Dodds Ashley and Rey Perez talk about probiotic-associated central venous catheter blood stream infections. The article reviewed in this episode can be found here: https://pubmed.ncbi.nlm.nih.gov/37260310/
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Episode Notes In this episode, Infectious Diseases fellow Dr. Rey Perez chats with DCASIP Executive Director Dr. Dev Anderson about the latest surgical site infection compendium updates. The article reviewed can be found here: https://www.cambridge.org/core/journals/infection-control-and-hospital-epidemiology/article/strategies-to-prevent-surgical-site-infections-in-acutecare-hospitals-2022-update/2F824B9ADD6066B29F89C8A2A127A9DC
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Episode NotesThis episode features Dr. April Dyer from DASON. The article reviewed in the episode can be found here: https://pubmed.ncbi.nlm.nih.gov/36999909/
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Episode NotesThis Episode features Drs. Shaefer Spires and Rey Perez from DASON. The article reviewed in this episode is available here: https://jamanetwork.com/journals/jama/fullarticle/2804245.JAMA. 2023;329(18):1579-1588. doi:10.1001/jama.2023.5728
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Episode NotesThis month, University of Kentucky HealthCare PGY2 Infectious Diseases Pharmacy Residents Becca and Kam are on their DASON rotation and are talking to DASON Digest listeners about antimicrobial susceptibility testing. The article reviewed in the episode is available here: https://pubmed.ncbi.nlm.nih.gov/36825480/
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Episode NotesThis month, University of Kentucky HealthCare PGY2 Infectious Diseases Pharmacy Residents Becca and Kam are on their DASON rotation and are talking to DASON Digest listeners about Hydrocortisone use in severe CAP. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36942789/
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Episode NotesThis episode features Drs. Libby Dodds Ashley and Rey Perez from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36774539/
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Episode NotesThis episode features Dr. Shaefer Spires, DASON Medical Director, and Dr. Ethan Brenneman, PGY2 Infectious Diseases Pharmacy Resident for Duke University Hospital. The documents reviewed in this episode are: https://duke.box.com/s/7zvupbr81euvcujzq20jbpbj0yuqnafy and https://duke.box.com/s/738zmcuz4voh2urm1j0o3v2i540ziczp
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Episode NotesThis episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36786646/
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Episode NotesThis episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36714291/
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Episode NotesThis episode features Drs. Shaefer Spires and Rey Perez from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/34325761/
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Episode NotesThis episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/36601545/
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Episode NotesThis episode features Dr. Libby Dodds Ashley from DASON and Dr. Rey Perez, our current Duke ID Fellow. Libby and Rey talk about some upcoming changes to the podcast, as well as discuss the following article: https://doi.org/10.1136/bmj.o2946
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This episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ash.2022.326.
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This episode features Dr. Travis Jones from DASON. The CDC report reviewed in this episode is available here: https://www.cdc.gov/antibiotic-use/stewardship-report/current.html.
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This episode features Dr. Shaefer Spires from DASON and Dr. Reinaldo (Rey) Perez from Duke Infectious Diseases. The article reviewed in this episode is available here: https://doi.org/10.1186/s12879-021-06391-2.
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This episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ice.2022.241.
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This episode features Dr. Libby Dodds Ashley and Dr. Rebekah Moehring from DASON. The article discussed in this episode is available here: https://doi.org/10.1093/cid/ciac787.
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This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab1034.
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This episode features Dr. April Dyer from DASON. The article discussed in this episode is available here: https://doi.org/10.1017/ice.2022.192.
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This episode features Dr. Travis Jones from DASON. The article discussed in this episode is available here: https://doi.org/10.1001/jamasurg.2019.0569.
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This episode features Dr. Shaefer Spires from DASON and Dr. Jennie Kwon from Washington University School of Medicine. The article discussed in this episode is available here: https://doi.org/10.1016/j.celrep.2022.110649.
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This episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/35877123/.
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This episode features Dr. Libby Dodds Ashley from DASON and Dr. Whitney Buckel from Intermountain Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciac515.
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This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab842.
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This episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ice.2022.83.
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This episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2792123.
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This episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1136/bmj-2021-0068229.
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This episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://pubmed.ncbi.nlm.nih.gov/35403600/.
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This episode features Drs. Jenni Thomas and Wes Johnson from University of Kentucky Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciac256.
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This episode features Drs. Jenni Thomas and Wes Johnson from University of Kentucky Healthcare. The articles reviewed in this episode are available here:
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This episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1017/ash.2022.34.
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This episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.ijantimicag.2022.106560.
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This episode features Dr. Shaefer Spires from DASON and Drs. Katie Olney and Katie Wallace from University of Kentucky Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1002/phar.2670.
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This episode features Dr. Melissa Johnson from DASON. The articles reviewed in this episode are available using the following links:
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This episode features Dr. Libby Dodds Ashley from DASON. The articles reviewed in this episode are available here:
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This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/s1473-3099(20)30857-4.
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This episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1038/s41591-021-01630-0.
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This episode features Dr. Travis Jones from DASON. Details regarding the FDA meeting on molnupiravir are available here: https://www.fda.gov/advisory-committees/advisory-committee-calendar/november-30-2021-antimicrobial-drugs-advisory-committee-meeting-announcement-11302021-11302021.
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This episode features Dr. Melissa Johnson from DASON. The CDC's 2021 report on antibiotic use in the United States is available here: https://www.cdc.gov/antibiotic-use/pdfs/stewardship-report-2021-H.pdf.
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This episode features Dr. Travis Jones from DASON and Dr. Elizabeth Keil, current PGY2 Infectious Diseases Resident at Duke University Hospital. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab865.
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This episode features Dr. Travis Jones from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab476.
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This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1001/jama.2021.9899.
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This episode features Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.cmi.2021.09.001.
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This episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires from DASON, Dr. Jessica Seidleman from Duke Infectious Diseases, and Dr. Christina Sarubbi from UNC Rex Healthcare. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciab747.
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This episode features Dr. Melissa Johnson from DASON. The articles reviewed in this podcast are available here:
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This episode features Dr. Travis Jones and Dr. Shaefer Spires from DASON.
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This episode features Dr. Angelina Davis from DASON. The articles reviewed in this episode are available using the following links:
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This episode features Dr. Shaefer Spires from DASON and Dr. Ted Hendershot from the Division of Infectious Diseases at Duke University. The article reviewed in this episode is available here: https://www.nejm.org/doi/full/10.1056/NEJMoa2020198.
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This episode features Dr. April Dyer from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciaa395.
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This episode features Dr. Travis Jones from DASON and Dr. Kevin Garey from the University of Houston College of Pharmacy. The articles reviewed in this episode are available for download using the following links:
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This episode features Dr. Elizabeth Dodds Ashley from DASON and Dr. Shaina Kwiatkowski from Henry Ford Macomb Hospital in Clinton Township, MI. The article by Kwiatkowski and colleagues reviewed in this episode is available here: https://doi.org/10.1093/ajhp/zxab218.
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This episode features Dr. Travis Jones from DASON and Dr. Jason Funaro from the Antimicrobial Stewardship Evaluation Team (ASET) at Duke. The article by Dr. Funaro and colleagues reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab214.
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This episode features Dr. Melissa Johnson from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/cid/ciaa212.
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This episode features Dr. April Dyer from DASON. The Best Practice Advice from the American College of Physicians is available here: https://doi.org/10.7326/M20-7355.
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This episode features Dr. Angelina Davis from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/S0140-6736(21)00313-5.
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This episode features Dr. Shaefer Spires from DASON. The article by Schweizer and colleagues is available here: https://doi.org/10.1093/cid/ciaa1572. The article by Dionne and Lee is available here: https://doi.org/10.1093/cid/ciab247.
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This episode features Dr. Elizabeth Dodds Ashley from DASON. The article reviewed in this episode is available here: https://doi.org/10.1093/ofid/ofab099.
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This episode features Dr. Cara Nys, a former PGY2 Infectious Diseases Resident at Duke, and Dr. Meredith Oliver, the lead author of the article reviewed in this episode and a Pediatric Infectious Diseases Pharmacist at the University of Minnesota Masonic Children's Hospital. The article reviewed by Meredith Oliver and colleagues is available here: https://doi.org/10.1128/AAC.01482-20.
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This episode features Dr. Angelina Davis from DASON. The CREDIBLE-CR study is available here: https://doi.org/10.1016/S1473-3099(20)30796-9. The APEKS-NP study is available here: https://doi.org/10.1016/S1473-3099(20)30731-3.
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This episode features Dr. Melissa Johnson from DASON. The CODA Trial reviewed in this podcast is available here: https://www.nejm.org/doi/10.1056/NEJMoa2014320. The APPAC II Trial is available here: https://jamanetwork.com/journals/jama/fullarticle/2775227.
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This episode features Dr. April Dyer and Dr. Shaefer Spires from DASON. The article reviewed in this episode is available here: https://doi.org/10.1016/j.cmi.2020.09.041. In addition, the systematic review and meta-analysis of secondary co-infection in patients with COVID-19 is available here: https://www.tarrn.org/covid.
For more information about DASON, please visit: https://dason.medicine.duke.edu.
This episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires from DASON. The DASON newsletter on the topic of COVID-19 Vaccine Q&As referenced in this episode is available for download here: https://dason.medicine.duke.edu/newsletters.
For more information about DASON, please visit: https://dason.medicine.duke.edu.
This episode features Drs. Elizabeth Dodds Ashley and Travis Jones from DASON and Dr. Kevin Garey from the University of Houston College of Pharmacy in Houston, Texas. The latest IDSA/SHEA C. difficile guidelines are available here: https://doi.org/10.1093/cid/ciab549.
For more information about the Duke Antimicrobial Stewardship Outreach Network (DASON), please visit: https://dason.medicine.duke.edu.
Episode Notes This episode features Dr. Elizabeth Dodds Ashley and Dr. Shaefer Spires. The article discussed in this podcast is available here: https://doi.org/10.1093/cid/ciaa1479.
For more information about the Duke Antimicrobial Stewardship Outreach Network (DASON), please visit: https://dason.medicine.duke.edu.