MedMaster by NURSING.com: Recent Episodes

Jon Haws, RN CCRN Alumnus

Brought to you by NURSING.com, based on their #1 Online Nursing Pharmacology Course . . . Visit nursing.com/50meds to get our list of the 50 most prescribed medications. YouTube: https://www.youtube.com/c/Nrsng/

The 140 MUST KNOW medications for nurses and nursing students. Each episode will discuss a commonly used medication in hospitals and ICUs that we as nurses will use each day. The #1 medication and pharmacology podcast. This is the perfect podcast for nursing students preparing for the NCLEX or practicing nurses preparing for the CCRN or other exams who want to increase their knowledge of pharmacology and pathopharm. The podcast for nurses and nursing students! Are you ready to sky rocket your nursing career to the next level? We cover test preparation (NCLEX CCRN etc), work life balance, pharmacology, theory, and more. Nursing is hard . . . learning it doesn't have to be! Jon Haws RN, the host has worked as a critical care registered nurse in a Level I Trauma hospital in Dallas, TX. Jon is the creator of NURSING.com. Visit the site and check out the books on Amazon.com We discuss current trends in the ICU, anatomy, physiology, nursing care, and much more. For full disclaimer information visit: nursing.com/about. NCLEX®, NCLEX-RN® are registered trademarks of the National Council of State Boards of Nursing, INC

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Generic Name lactulose

Trade Name Kristalose

Indication Constipation, portal-systemic encephalopathy

Action draws water into the stool and softens stool, inhibits ammonia passing into the colon

Therapeutic Class laxative

Pharmacologic Class osmotic

Nursing Considerations • use caution with DM
• may cause cramps, abdominal distention, hyperglycemia
• assess mental status, ammonia levels, abdominal distention
• patient should average 2-3 bowel movements per day

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Generic Name ketorolac

Trade Name Toradol

Indication pain

Action pain relief due to prostaglandin inhibition by blocking of the enzyme cyclooxygenase (COX)

Therapeutic Class nonsteroidal anti-inflammatory agents, nonopioid analgesics

Pharmacologic Class pyrroziline carboxylic acid

Nursing Considerations • may cause GI bleeding, Stevens-Johnson Syndrome, anaphylaxis, drowsiness
• should not exceed 5 days of therapy
• bleeding risk increased with garlic, ginger, and ginkgo
• may decrease effectiveness of hypertensive medications and diuretics

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Generic Name isoniazide

Trade Name INH

Indication tuberculosis

Action Inhibits synthesis of mycobacterial cell wall

Therapeutic Class Antitubercular

Pharmacologic Class none

Nursing Considerations • can cause jaundice
• may cause peripheral neuropathy, seizures, hepatitis
• patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese)
• monitor liver function tests
• complete full course of therapy (6-12 months)
• often used in combination with Rifampin

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Generic Name radioactive iodine

Trade Name none

Indication thyroidectomy pretreatment, thyrotoxic crisis, radiation exposure

Action inhibits the release of thyroid hormones

Therapeutic Class Antithyroid Agent, control of hyperthyroidism

Pharmacologic Class none

Nursing Considerations • may cause GI bleeding, diarrhea, hypothyroidism, goiter
• monitor for hypersensitivity

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Generic Name Insulin Regular

Trade Name Humulin R/Novolin R

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Subcutaneous | 30-45 min | 1-5 | 4.5-6h |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Generic Name Aspart, Lispro, Glulisine

Trade Name Novolog, Humalog, Apidra

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route |  Onset | Peak | Duration | | Aspart | 10-20 min | 1-3 hr | 3-5 hr | | Glulisine | 15 min | 1 hr | 2-4 hr | | Lispro | 15 min | 1-1.5 hr | 3-4 hr |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Generic Name Insulin detemir, Insulin glargine

Trade Name Levemir, Lantus

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Detemir | 3-4 hr | 3-14 hr | 24 hr | | Glargine | 3-4 hr | none | 24 hr |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Generic Name Insulin NPH

Trade Name Humulin N, Novolin N

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Subcutaneous | 1-2 hr | 4-12hr | 18-24hr |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Generic Name indomethacin

Trade Name Indocin

Indication Inflammatory disorders when patients do not respond to other medications

Action Decreases pain and inflammation by inhibiting prostaglandin synthesis

Therapeutic Class antirheumatics, ductus arteriosus patency adjuncts (IV only), nonsteroidal anti-inflammatory agents

Pharmacologic Class none

Nursing Considerations • monitor for hepatitis and GI bleeding
• monitor for dizziness, drowsiness, and headache
• assess for anaphylactic reaction
• aspirin may decrease effectiveness
• monitor renal labs
• shake suspension before administration
• patient should wear sunscreen and protective clothing to protect against photosensitivity

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Generic Name ibuprofen

Trade Name Advil / Motrin

Indication Mild to moderate pain, inflammatory states

Action Decreases pain and inflammation by inhibiting prostaglandins

Therapeutic Class antipyretics, antirheumatics, nonopioid analgesics, nonsteroidal anti-inflammatory agents

Pharmacologic Class nonopioid analgesics

Nursing Considerations • may cause GI bleeding, hepatitis, Stevens-Johnson Syndrome
• may cause anaphylaxis
• monitor for headache, nausea, vomiting, constipation
• therapy should be discontinued after first sign of rash
• monitor renal and liver labs
• patient should avoid using alcohol

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name hydromorphone

Trade Name Dilaudid

Indication moderate to severe pain

Action alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex

Therapeutic Class Opioid Analgesic, allergy, cold and cough remedies, antitussive

Pharmacologic Class opioid agonist

Nursing Considerations • Assess BP, respirations, and pulse before and during administration – medication causes general
CNS depression
• Narcan (nalaxone) is the antidote for overdose
• use caution with concurrent use of MAOI – avoid use within 14 days of each other
• may be used as an antitussive
• advised to dilute with NS prior to administration and to administer slowly to decrease CNS
depression

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Generic Name hydrocodone/acetaminophen

Trade Name Vicodin, Lortab, Norco

Indication management of moderate to severe pain

Action alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex

Therapeutic Class opioid Analgesic, allergy, cold and cough remedies, antitussive

Pharmacologic Class opioid agonists, nonopioid analgesic combinations

Nursing Considerations • use caution with concurrent use of MAOI – avoid use within 14 days of each other
• hypotension – monitor hemodynamics and respirations after administering
• may increase ICP use caution with head trauma
• Narcan (nalaxone) is the antidote for overdose
• DO NOT exceed 4g of acetaminophen per day

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Generic Name hydralazine

Trade Name Apresoline

Indication hypertension

Action arterial vasodilation by unclarified mechanism

Therapeutic Class anti-hypertensive

Pharmacologic Class vasodilator

Nursing Considerations • may cause tachycardia, sodium retention, arrhythmias, angina
• use caution with MAOIs
• monitor blood pressure
• instruct patient on how to take blood pressure

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Generic Name haloperidol

Trade Name Haldol

Indication Schizophrenia, mania, aggressive and agitated patient

Action Alters the effect of dopamine

Therapeutic Class Antipsychotic

Pharmacologic Class butyrophenones

Nursing Considerations • extrapyramidal symptoms, tardive dyskinesia
• use caution in QT prolongation
• may cause seizures, constipation, dry mouth, agranulosytosis
• assess for hallucinations
• monitor hemodynamics
• monitor for neuroleptic malignant syndrome (fever, muscular rigidity, altered mental status, and
autonomic dysfunction)
• monitor CBC with differential

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name guaifenesin

Trade Name Mucinex

Indication Cough suppression, expectorant

Action Decreases viscosity of and mobilizes secretions

Therapeutic Class allergy, cold and cough remedies, expectorant

Pharmacologic Class none

Nursing Considerations • patient should avoid over the counter cold medications
• assess lung sounds
• maintain adequate fluid intake

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Glipizide

Trade Name Glucotrol

Indication Type 2 diabetes mellitus

Action Stimulates release of insulin from the beta cells in the pancreases and leads to increased sensitivity to insulin

Therapeutic Class Anti-diabetic

Pharmacologic Class Sulfonylureas

Nursing Considerations • May cause aplastic anemias, hypoglycemia, photosensitivity, dizziness,
drowsiness, headache, diarrhea
• Monitor CBC, assess for allergy to sulfonamides
• Beta blockers may increase signs of hypoglycemia
• Instruct patient on how to check blood sugars and
• Instruct patient on importance of carrying source of sugar in case of
hypoglycemia

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Generic Name Gentamicin

Trade Name Cidomycin

Indication Treatment of gram negative infections when penicillin is ineffective

Action Inhibits bacterial protein synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Aminoglycoside

Nursing Considerations • Causes tinnitus-hearing loss/do not administer with penicillin
• Use caution in renal impairment
• Assess for infection
• Obtain cultures prior to therapy
• Monitor liver function tests
• Monitor blood levels of drug

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Generic Name Gabapentin

Trade Name Neurontin

Indication Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines

Action Exact method of action unknown, may play a role in stabilizing neural membranes

Therapeutic Class Analgesic adjuncts, anticonvulsants, mood stabilizers

Pharmacologic Class None

Nursing Considerations • May cause suicidal thoughts, confusion, depression, drowsiness, ataxia, facial
edema, hypertension
• Monitor pt closely for changes in behavior and depression
• Assess seizure activity
• Assess pain level
• Patient should take medications exactly as prescribed

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Trade Name Lasix

Indication Edema, hypertension

Action Prevents reabsorption of sodium and chloride in the kidneys, increase excretion of
water, sodium, chloride, magnesium, potassium

Therapeutic Class Diuretics

Pharmacologic Class Loop diuretics

Nursing Considerations • Use caution with liver disease
• May cause hypotension, dry mouth, excessive urination, dehydration,
electrolyte abnormalities, metabolic alkalosis
• Hypokalemia may lead to increase risk of digoxin toxicity
• Monitor renal panel
• Use caution with other antihypertensives
• Causes arthritic symptoms/do not administer with aminoglycosides due to
ototoxicity

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Generic Name Fluticasone

Trade Name Flovent, Flonase

Indication prophylactic asthma treatment

Action locally acting anti-inflammatory

Therapeutic Class antiasthmatics, anti-inflammatory (steroid)

Pharmacologic Class Corticosteroids, Inhalation

Nursing Considerations • use cautiously with untreated infections and suppressed immune function
• may cause headache, insomnia, bronchospasm, nasal congestion, adrenal suppression
• monitor patient’s respiratory status
• may lead to decreased bone density
• instruct patients using corticosteroids and bronchodilators that they need to use
bronchodilators first.
• instruct patient to stop smoking

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Generic Name Fluoxetine

Trade Name Prozac

Indication Depressive disorder, OCD, bulimia, panic disorder, bipolar, anorexia, ADHD, DM
neuropathy, obesity

Action Inhibits reuptake of serotonin allowing it to persist longer in the synaptic cleft

Therapeutic Class Antidepressant

Pharmacologic Class SSRI

Nursing Considerations • Do not use while taking MAOIs
• May cause suicidal thoughts, drowsiness, anxiety, sexual dysfunction,
insomnia, palpitations
• Monitor closely for serotonin syndrome
• Concurrent use with certain medications may lead to QT prolongation
• Monitor mood changes and assess for suicidal ideation
• Monitor nutrition status
• May cause elevated liver enzymes
• Instruct pt to maintain good oral hygiene

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Generic Name Ferrous sulfate

Trade Name Feosol

Indication Prevention and treatment of iron-deficiency anemia

Action Iron is essential for hemoglobin, myoglobin and enzymes, it is transported to
organs where it becomes part of iron stores

Therapeutic Class Antianemics

Pharmacologic Class Iron supplements

Nursing Considerations • May cause seizures, hypotension, constipation, epigastric pain, diarrhea, skin
staining, anaphylaxis
• Assess nutritional status, bowel function
• Monitor hemoglobin, hematocrit, iron levels
• May cause elevated liver enzymes
• Take on an empty stomach to increase absorption/vitamin c helps with
absorption
• Use z-track for IM injections

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Generic Name Fentanyl

Trade Name Sublimaze

Indication Supplement to general anesthesia, continuous IV infusion for purpose of analgesia

Action Binds to opiate receptors in CNS altering perception of pain, producing CNS
depression

Therapeutic Class Opioid Analgesic

Pharmacologic Class Opioid agonists

Nursing Considerations • Use caution with increased ICP, head trauma, adrenal insufficiency
• Avoid use with MAOIs
• May cause apnea, laryngospasm, decreased respirations, bradycardia,
hypotension
• Do not consume grapefruit while taking this medication
• Monitor hemodynamics during administration
• Assess patient pain scale frequently

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Generic Name Famotidine

Trade Name Pepcid

Indication Short term treatment of active ulcer, GERD, treatment of heartburn, indigestion,
management of Zollinger Ellison syndrome, prevention of GI bleeding in critically
ill patients, management of symptoms associated with overuse of NSAIDs

Action Blocks action of histamine located in gastric parietal cells, inhibits gastric acid
secretion

Therapeutic Class Antiulcer agent

Pharmacologic Class Histamine H2 antagonist

Nursing Considerations • May cause arrhythmias, agranulocytosis, aplastic anemias
• Assess for abdominal pain and occult blood
• Monitor CBC
• Instruct pt to increase fluid and fiber intake to prevent constipation

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Escitalopram

Trade Name Lexapro

Indication Major depressive disorder, anxiety disorder, PCD, PTSD, social phobia

Action Increases the extracellular levels of serotonin in the synaptic cleft by selectively
inhibiting its reuptake

Therapeutic Class Antidepressant

Pharmacologic Class SSRI

Nursing Considerations • Contraindicated with MAOI
• May cause suicidal thoughts, insomnia, drowsiness, diarrhea, nausea,
serotonin syndrome
• May cause QT prolongation with certain medications
• Assess for sexual dysfunction
• May take 4-6 weeks for full affect to take place
• Monitor for serotonin syndrome (mental changes, NV, tachycardia,
hyperthermia)

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Generic Name Erythromycin

Trade Name E-Mycin

Indication Useful in place of penicillin when patient cannot take penicillin, upper and lower
respiratory tract infections, otitis media, skin infections, pertussis, syphilis,
rheumatic fever

Action Bacteriostatic: suppresses bacterial protein synthesis

Therapeutic Class Anti-infective

Pharmacologic Class Macrolide

Nursing Considerations • Causes QT prolongation, ventricular arrhythmias
• Diarrhea
• Asses infection
• Monitor liver function tests
• Instruct patient to finish medication dosage even if they are feeling better
• Medication should not be shared

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Epoetin

Trade Name Epogen

Indication Anemia

Action Stimulates erythropoiesis (production of RBCs)

Therapeutic Class Antianemic

Pharmacologic Class Hormones

Nursing Considerations * Assess dialysis shunts * Contraindicated in albumin hypersensitivity * May cause + Seizures + CHF + MI + CVA + Hypertension * Do not shake vial * Initiate seizure precautions * Monitor + Bleeding times + Signs of anemia

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Epinephrine

Trade Name Adrenalin, EpiPen

Indication Asthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct

Action Affects both beta1 and beta2 also has alpha agonist properties resulting in bron-
chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.

Therapeutic Class Antiasthmatic, bronchodilator, vasopressor

Pharmacologic Class Adrenergic agonist

Nursing Considerations • Side effects include: angina, tachycardia, hypertension, restlessness,
nervousness, hyperglycemia
• Use with MAOI may lead to hypertensive crisis
• Patients should not use stimulants (caffeine, guarana, etc)
• Excessive use may cause bronchospasm
• Assess lung sounds, pulse, BP, and other hemodynamic parameters
• Monitor for chest pain
• Instruct patient to use as directed
• Patient should insure adequate fluid intake to liquefy secretions
• Mouth should be rinsed after inhalation
• Beta blockers may negate effects
• May increase blood glucose levels

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Generic Name Enoxaparin

Trade Name Lovenox

Indication Prevention of VTE, DVT, and PE

Action Prevents thrombus formation by potentiating the inhibitory effect of antithrom-
bin on factor Xa and thrombin. Enoxaparin is a low molecular weight heparin.

Therapeutic Class Anticoagulant

Pharmacologic Class Antithrombotic

Nursing Considerations • Contraindicated in pork hypersensitivity
• Monitor for signs of bleeding
• Administer in subcutaneous tissue
• DO NOT eject air bubble prior to injection
• DO NOT aspirate or massage site

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Enalapril

Trade Name Vasotec

Indication hypertension, management of CHF

Action Block conversion of angiotensin I to angiotensin II, increases renin levels and
decreases aldosterone leading to vasodilation

Therapeutic Class Antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • May cause hypersensitivity (allergic) reactions and angioedema (swelling of face, lips, tongue, throat)

• Can cause neutropenia – check WBCs regularly

• Use cautiously with potassium supplements and potassium sparing diuretics.
• Use cautiously with diuretic therapy
• Administer 1 hour before meals
• Monitor blood pressure often
• Monitor weight and fluid status
• Monitor renal profile
• Monitor CBC frequently
• Dry cough

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Generic Name dopamine

Trade Name Inotropin

What is the indication for Dopamine? used to improve blood pressure, cardiac output, and urine output

Action Smaller doses result in renal vasodilation
Doses 2-10mcg/kg/min result in cardiac stimulation by acting on beta1 receptors
Doses >10mcg/kg/min stimulate alpha receptors leading to vasoconstriction (↑SVR)

What is the therapeutic class for Dopamine? inotropic, vasopressor

Pharmacologic Class adrenergic

Nursing Considerations for Dopamine (Inotropin) • Monitor hemodynamics closely: BP, HR, EKG, CVP, and PAOP if available
• Obtain parameters for hemodynamic values
• Titrate to obtain appropriate BP (more potent vasoconstrictors may be required)
• Irritation may occur at IV site
• Beta blockers may counteract therapeutic effects

Dopamine Audio Lecture

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Generic Name Dobutamine

Trade Name Dobutrex

Indication Short term management of heart failure

Action Dobutamine has a positive inotropic effect (increases cardiac output) with very
little effect on heart rate. Stimulates Beta1 receptors in the heart.

Therapeutic Class Inotropic

Pharmacologic Class Beta-adrenergic agonist

Nursing Considerations • Monitor hemodynamics: hypertension, ↑HR, PVCs
• Skin reactions may occur with hypersensitivity
• Beta blockers may negate therapeutic effects of dobutamine
• Monitor cardiac output
• Monitor peripheral pulses before, during, and after therapy
• DO NOT confuse dobutamine with dopamine

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Generic Name Divalproex

Trade Name Depakote

Indication Seizures, manic episodes, prevention of headache

Action Increases the level of GABA (inhibitory neurotransmitter) in CNS

Therapeutic Class Anticonvulsant, vascular headache suppressants

Pharmacologic Class None

Nursing Considerations • May cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity, pancreatitis • Increases risk for bleeding with Warfarin • Use caution with MAOIs • Monitor liver function tests

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Trade Name Lomotil

Indication Treatment for diarrhea

Action Inhibits GI motility via anticholinergic effects

Therapeutic Class Antidiarrheal

Pharmacologic Class Anticholinergic

Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration • Structurally related to opioids so use caution with patients that have allergies to opioids • May cause constipation, tachycardia, dizziness, ileus • Monitor liver function as the medication is excreted by the liver • Ensure that client is taking medication as prescribed and not double dosing

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Generic Name Diphenhydramine

Trade Name Benadryl

Indication Allergy, anaphylaxis, sedation, motion sickness, antitussive

Action Antagonizes effects of histamine, CNS depression

Therapeutic Class Allergy, cold and cough remedy, antihistamine, antitussive

Pharmacologic Class Antihistamine

Nursing Considerations • May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache • Anticholinergic effects (dry mouth, blurred vision, constipation, sedation) • Assess purpose of medication prior to giving it • Assess allergies, sleep patterns, cough and lung sounds • Patient should avoid other over-the-counter cough and cold remedies

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Generic Name Diltiazem

Trade Name Cardizem

Indication Hypertension, angina, SVT, AFib, aflutter

Action Inhibits calcium transport resulting in inhibition of excitation and contraction, leads to depression of AV and SA node leading to decreased HR, leads to vasodi- latation and decreased blood pressure.

Therapeutic Class Antianginals, antiarrhythmics, antihypertensive

Pharmacologic Class Ca Channel Blocker (Benzothiazepine)

Nursing Considerations • Contraindicated in 2nd and 3rd AV block • May cause arrhythmias, CHF, bradycardia, peripheral edema, gingival hyperplasia • Increases digoxin levels • Don’t drink grapefruit juice • Assess for signs of CHF • Monitor EKG continuously • Tell patient to change positions slowly • Monitor serum potassium • Instruct pt on how to take blood pressure

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Generic Name Digoxin

Trade Name Lanoxin

Indication CHF, AFib, A-flutter

Action Positive inotropic effect (increases force of myocardial contraction), prolongs refractory period, ↓ conduction through SA and AV nodes. Essentially digoxin is given to increase cardiac output and slow the rate.

Therapeutic Class Antiarrhythmic, inotropics

Pharmacologic Class Digitalis glycosides

Nursing Considerations • Excreted by kidneys • Assess patient for hypersensitivity • Contraindicated with uncontrolled ventricular arrhythmias • Hypokalemia increase risk for toxicity • Hypercalcemia ↑ risk for toxicity • Use caution with diuretic use as they may cause electrolyte abnormalities that can lead to toxicity • Assess patient for cardiac arrhythmias including bradycardia • Signs of toxicity include vision changes (blurred vision, yellow, green vision disturbances) • Monitor pulse rate for 1 full minute prior to dosing patient (hold for pulse

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Generic Name Diazepam

Trade Name Valium

Indication Anxiety, pre-op sedation, conscious sedation, treatment of seizures, insomnia, management of alcohol withdrawal

Action Decreases the effects of voltage gated sodium channels to depresses the CNS

Therapeutic Class Antianxiety agents, anticonvulsants, sedative/hypnotics, skeletal muscle relax- ants (centrally acting)

Pharmacologic Class Benzodiazepine

Nursing Considerations • Contraindicated in hepatic dysfunction • Use caution with renal impairment • Can cause dizziness, drowsiness, lethargy, hypotension, physical depen- dence, tolerance • Instruct patient to take as directed • Caution to avoid alcohol use • Flumazenil (Romazicon) is the reversal agent

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Generic Name Dexamethasone

Trade Name Decadron

Indication Manage cerebral edema, assess for Cushing’s Disease

Action Suppress inflammation and normal immune response. Used in inflammatory states to decrease inflammation.

Therapeutic Class Antiasthmatics, corticosteroids

Pharmacologic Class Corticosteroids

Nursing Considerations • Excreted by the liver – monitor liver profile • Avoid in active untreated infections • May cause CNS alterations • May cause peptic ulcers • May cause Cushingoid appearance (buffalo hump, moon face) • Weight gain • Osteoporosis • Decrease wound healing • May elevate blood sugars • May increase cholesterol and lipid values

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I am excited to bring to you the NURSING.com SOCK Method, with proven tips to help you master pharmacology.   When I surveyed 200 nursing students, 66% said that their most difficult subject was nursing pharmacology.  However, the issue is often overlooked.

There are a lot of schools that don't have dedicated pharmacology courses and instead roll it up into other parts of the program.  But that is devastating to me because the one thing we do more than almost anything else in our careers as nurses is give medication.

So today I'm gonna introduce you to something called the SOCK Method for mastering nursing pharmacology.  We are doubling down on our focus on pharmacology in this podcast.  After listening to this, I am confident that you will be able to become a master of nursing pharmacology.

SOCK Method

  • S – Side Effects
  • O – Organs
  • C – Class/Considerations/Cards
  • K – Know (or Must Know)
  • The Correct Order

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Generic Name Cyclosporine

Trade Name Sandimmune

Indication Prevention of rejection in transplantation, treatment of severe RA, management of ulcerative colitis

Action Inhibits normal immune response primarily by decreasing the activity of T cells

Therapeutic Class Immunosuppressant, antirheumatics (DMARD)

Pharmacologic Class Polypeptides (cyclic)

Nursing Considerations • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V, gingival hyperplasia • Increases immune suppression with corticosteroids • Avoid grapefruit juice while taking this medications • Assess for signs of organ rejection • Monitor renal panel, liver enzymes • Take medication as directed • Lifelong therapy required for transplant patients • Instruct pt on how to take blood pressure

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Generic Name Cortisone

Trade Name Cortone

Indication Management of adrenocortical insufficiency (Addison’s Disease). Replace cortisol in states of deficiency, suppress inflammation and normal immune response.

Action The adrenal glands sit on top of the kidneys. The adrenal glands excrete steroid hormones, including cortisol that play a role in increasing blood sugars, immune suppression, and metabolism of fat, protein, and carbohydrates, as well as decreasing bone formation.

Therapeutic Class Antiasthmatics, corticosteroids

Pharmacologic Class Corticosteroids

Nursing Considerations • Excreted by the liver – monitor liver profile • Avoid in active untreated infections • May cause CNS alterations • May cause peptic ulcers • May cause Cushingoid appearance (buffalo hump, moon face) • Weight gain • Osteoporosis • Decrease wound healing • May elevate blood sugars • May increase cholesterol and lipid values

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Trade Name Paveral

Indication Management of pain, diarrhea, cough suppressant

Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility.

Therapeutic Class Allergy, cold, cough remedy, antitussive, opioid analgesic

Pharmacologic Class Opioid agonist

Nursing Considerations • May cause alterations in mentation, hypotension, constipation, nausea, vomiting • Assess BP, pulse, and respiratory rate prior to administration and frequently during administration • Use caution if patient is receiving MAO Inhibitors • Narcan (naloxone) is the antidote for opioid agonists

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Generic Name Clopidogrel

Trade Name Plavix

Indication Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome

Action Inhibits platelet aggregation

Therapeutic Class Antiplatelet agent

Pharmacologic Class Platelet aggregation inhibitors

Nursing Considerations • May cause GI bleeding, neutropenia, hypercholesterolemia • May increase risk for bleeding in warfarin, aspirin, heparin • Can increase risk for bleeding with garlic, ginkgo, ginger • Monitor for signs of bleeding • Monitor bleeding times • Monitor CBC and platelet count • Discontinue use 5-7 days before surgery

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Generic Name Clindamycin

Trade Name Cleocin

Indication Skin infections, respiratory tract infections, septicemia, intra-abdominal infections, osteomyelitis

Action Bacteriostatic: inhibits protein synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Lincosamide

Nursing Considerations • Arrhythmias, pseudomembranous colitis, diarrhea, phlebitis • Monitor bowel function • Assess for infection, obtain cultures prior to therapy • Monitor liver function tests • Monitor CBC

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Generic Name Ciprofloxacin

Trade Name Cipro

Indication Urinary tract infections, gonorrhea, respiratory tract infections, bronchitis, pneumonia, skin and bone infections, infectious diarrhea, abdominal infections

Action Inhibits bacterial DNA synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Fluoroquinolone

Nursing Considerations • Contraindicated in allergies • May cause QT prolongation, avoid use with other drugs that can cause QT prolongation • Can cause seizures, arrhythmias, pseudomembranous colitis, anaphylaxis, Stevens Johnson syndrome • May decrease effects of phenytoin • Monitor renal panel • Assess for infection, obtain cultures prior to therapy • Monitor liver function tests

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Generic Name Cimetidine

Trade Name Tagamet

Indication Treatment of duodenal ulcers, GERD, heartburn, Zollinger Ellison syndrome, prevention of GI bleeding in critical patients.

Action Inhibits action of histamine leading to inhibition of gastric acid secretion

Therapeutic Class Antiulcer agent

Pharmacologic Class Histamine H2 antagonist

Nursing Considerations • Increases serum level of warfarin • Can lead to respiratory infection (green sputum) • Monitor for arrhythmias • May cause agranulocytosis, aplastic anemia • Monitor CBC during therapy • Take medication as directed • Instruct patient to increase fluid and fiber intake to decrease constipation

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Generic Name Chlorpromazine

Trade Name Thorazine

Indication Second line treatment of schizophrenia and psychosis, nausea/vomiting, pre-op sedation, acute intermittent porphyria, headache, bipolar

Action Exhibits anticholinergic activity, alters effects of dopamine in CNS

Therapeutic Class Antipsychotic, antiemetic

Pharmacologic Class Phenothiazines (dopamine D2 receptor antagonist)

Nursing Considerations • May cause neuroleptic malignant syndrome, sedation, tardive dyskinesia, hypotension, agranulocytosis • Assess mental status prior to and during treatment • Monitor blood pressure • Ensure patient is taking medication • Monitor CBC and liver function tests • Instruct patient not to skip doses or double dose.

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Generic Name Cephalexin

Trade Name Keflex

Indication Skin infections, pneumonia, UTI, otitis media

Action Bactericidal: binds to bacterial cell wall leading to cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 1st generation

Nursing Considerations • Contraindicated with cephalosporin and serious penicillin allergies. • May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at IV site, anaphylaxis • Assess infection and allergies • Obtain cultures prior to therapy • Monitor bowel function • May lead to superinfection • May cause elevated liver enzymes

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Generic Name Celecoxib

Trade Name Celebrex

Indication Osteoarthritis, rheumatoid arthritis, acute pain

Action Decreases pain and inflammation by inhibiting synthesis of prostaglandins

Therapeutic Class Antirheumatics/NSAID

Pharmacologic Class Cox 2 inhibitor

Nursing Considerations • Use caution with cardiovascular disease • Increases risk for MI, CVA, thrombosis • May cause GI bleeding, Stevens-Johnson syndrome, dermatitis • Notify provider for new-onset abdominal pain or black stool

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Generic Name Cefdinir

Trade Name Omnicef

Indication Treatment of skin infections, otitis media

Action Bactericidal, binds to bacterial cell wall causing cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 3rd generations

Nursing Considerations • Contraindicated in cephalosporin and possibly penicillin allergies • May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at IV site, anaphylaxis • Assess infection and allergies • Obtain cultures prior to therapy • Monitor bowel function • Monitor for bleeding • May lead to superinfection

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Generic Name Cefaclor

Trade Name Ceclor

Indication Treatment of respiratory tract infections, skin infections, otitis media

Action Bactericidal, binds to bacterial cell wall causing cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 2nd generations

Nursing Considerations • Contraindicated in cephalosporin and possibly penicillin allergies • May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at IV site, anaphylaxis • Assess infection and allergies • Obtain cultures prior to therapy • Monitor bowel function • May lead to superinfection

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Generic Name Carbidopa/levodopa

Trade Name Sinemet

Indication Parkinson’s disease

Action Levodopa is converted to dopamine and works as a neurotransmitter, carbidopa prevents the destruction of levodopa allowing it to cross the blood brain barrier

Therapeutic Class Antiparkinson agent

Pharmacologic Class Dopamine Agonist

Nursing Considerations • May cause orthostatic hypotension • May cause dark urine • Weeks to months to take effect • Do not use with MAOIs • Do not use with glaucoma, melanoma • Assess for parkinsonian symptoms • Instruct patient to take as directed

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Generic Name Captopril

Trade Name Capoten

Indication Hypertension, management of CHF, decrease progression of DM neuropathy

Action Block conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone leading to vasodilation

Therapeutic Class Antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • Can cause neutropenia – check WBCs regularly • Use cautiously with potassium supplements and potassium sparing diuretics • Use cautiously with diuretic therapy • Administer 1 hour before meals • Monitor blood pressure often • Monitor weight and fluid status • Monitor renal profile • Monitor CBC frequently • May lead to Rhabdomyolysis • Dry cough

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Generic Name Calcium carbonate

Trade Name Tums/Rolaids

Indication Treatment of hypocalcemia, prevention of postmenopausal osteoporosis, treat- ment of hyperkalemia and hypermagnesemia, used as antacid

Action Calcium is essential for nervous, muscular, and skeletal systems, helps maintain cell membranes, aids in transmission of nerve impulses and muscle contraction, aids in blood formation and coagulation

Therapeutic Class Mineral and electrolyte replacements/supplements

Pharmacologic Class Antacids

Nursing Considerations • May cause cardiac arrest and arrhythmias • Monitor hemodynamics • May causes hypotension, bradycardia, and arrhythmias • Hypercalcemia can increase risk for digoxin toxicity • Instruct pt on foods that contain Vitamin D and encourage adequate intake • Monitor parathyroid hormone

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Generic Name calcium acetate

Trade Name PhosLo

Indication treatment of hypocalcemia, prevention of post-menopausal osteoporosis, treatment of hyperkalemia and hypermagnesaemia, adjunct in cardiac arrest, control of hyperphosphatemia with ESRD. Binds to phosphate in food and prevents absorption.

Action calcium is essential for nervous muscular and skeletal systems, helps maintain cell membranes, aids in transmission of nerve impulses and muscle contraction, aids in blood formation and coagulation

Therapeutic Class mineral and electrolyte replacements/supplements

Pharmacologic Class antacids

Nursing Considerations • may cause cardiac arrest and arrhythmias • phlebitis at site of insertion • monitor hemodynamics • may cause hypotension, bradycardia, and arrhythmias • hypercalcemia can increase risk for digoxin toxicity • administer slowly • instruct pt on foods that contain Vitamin D and encourage adequate intake. • monitor parathyroid hormone

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Generic Name butorphanol

Trade Name Stadol

Indication moderate to severe pain, labor pain, sedation

Action alters perception and response to pain by binding to opiate receptors in CNS

Therapeutic Class Opioid Analgesic

Pharmacologic Class opioid agonists/antagonists

Nursing Considerations • use caution with concurrent use of MAOIs • may cause confusion, hallucinations, sedation • monitor for CNS depression • assess blood pressure pulse and respirations during administration • administer slowly through an IV line

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Generic Name Buspirone

Trade Name Buspar

Indication Management of anxiety

Action Relieves anxiety by binding to dopamine and serotonin receptors

Therapeutic Class Antianxiety

Pharmacologic Class Azapirone

Nursing Considerations • Do not administer concurrently with MAOI or grapefruit juice • May lead to dizziness, drowsiness, fatigue, and weakness • Patient may experience chest pain, palpitations, tachycardia • Instruct patient to take as directed • Instruct patient to avoid alcohol and other CNS depressants

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Generic Name Bupropion

Trade Name Wellbutrin

Indication Depression, smoking cessation, treat ADHD in adults

Action Not well understood, ↑ dopaminergic and noradrenergic transmission via reuptake

Therapeutic Class Antidepressants, smoking deterrents

Pharmacologic Class Aminoketones

Nursing Considerations • May lead to seizures, suicidal thoughts • Do not administer if patient is taking MAOI • Use caution with renal and liver impairment • Assess mental status • Instruct patient to avoid alcohol (may lead to hallucinations, seizures, anxiety)

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Generic Name Bismuth subsalicylate

Trade Name Kaopectate, Pepto-Bismol

Indication Diarrhea, heartburn, indigestion, H. pylori associated ulcer

Action Stimulates the absorption of fluids and electrolytes in the intestinal wall, reduction in hypermotility of the stomach, and binds to toxins.

Therapeutic Class Antidiarrheal, antiulcer, antacid

Pharmacologic Class Absorbent

Nursing Considerations • Contraindicated in aspirin hypersensitivity • Increase risk for impaction with geriatric and pediatric patients • Monitor liver profile • Bismuth may interfere with radiologic exams

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Generic Name Bisacodyl

Trade Name Dulcolax

Indication Treatment of constipation, bowel regimen

Action Stimulates enteric nerves to cause peristalsis which leads to fluid accumulation in the colon

Therapeutic Class Laxatives

Pharmacologic Class Stimulant laxatives

Nursing Considerations • May lead to hypokalemia • May cause abdominal pain and cramps • Not for use within 1 hour of taking milk product • Assess for abdominal distention and bowel function • Instruct patient to drink 1500-2000 mL/day during therapy • Monitor fluid and electrolyte levels • Instruct patient to take as ordered

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Generic Name Benztropine

Trade Name Cogentin

Indication Treatment for Parkinson’s disease

Action Exhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors

Therapeutic Class Antiparkinson agent

Pharmacologic Class Anticholinergic

Nursing Considerations • May lead to arrhythmias, hypotension, palpitations, and tachycardia • Anticholinergic effects like constipation, dry mouth • Assess for extrapyramidal symptoms • Instruct patient to take as directed • Instruct patient to maintain good oral hygiene

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Azithromycin

Trade Name Zithromax

Indication URI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis

Action Inhibits bacterial protein synthesis

Therapeutic Class Agents for atypical mycobacterium, anti-infectives

Pharmacologic Class Macrolide

Nursing Considerations • May lead to pseudomembranous colitis, pain, diarrhea, nausea, Stevens-Johnson syndrome, angioedema • May increase risks for warfarin toxicity • Monitor patient for signs of anaphylaxis • Instruct patient to notify physician for diarrhea, or blood or pus in stool • Instruct patient to take medication exactly as prescribed

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Atorvastatin

Trade Name Lipitor

Indication Management of high cholesterol (hypercholesterolemia), primary prevention of cardiovascular disease

Action Lowers total cholesterol as well as LDL while slightly increasing HDL. Inhibits HMG-CoA reductase which plays a role in the liver in cholesterol formation

Therapeutic Class Lipid-lowering agent

Pharmacologic Class HMG-CoA reductase inhibitor

Similar Medications Simvastatin (Zocor), rosuvastatin (Crestor)

Nursing Considerations • Contraindicated in active liver disease • May cause rhabdomyolysis • Monitor renal function • Monitor serum cholesterol before, about 4 weeks after starting, and fre- quently during drug therapy • Monitor liver function tests • Instruct patient to report muscle weakness (sign of rhabdomyolysis)

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Atropine

Trade Name Atropen

Indication Decreases oral and respiratory secretions, treats sinus bradycardia and heart block, treatment of bronchospasm

Action Atropine is an anticholinergic which means that it inhibits the effects of the parasympathetic nervous system, specifically acetylcholine. This inhibition causes increase in HR, bronchodilation, decreased GI and respiratory secretions.

Therapeutic Class Antiarrhythmic

Pharmacologic Class Anticholinergic, antimuscarinic

Nursing Considerations • Avoid in acute hemorrhage, tachycardia, and angle closure glaucoma • Monitor patient for tachycardia and palpitations • May cause urinary retention in elderly patients • Patients may experience constipation due to slowed GI motility

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Amlodipine

Trade Name Norvasc

Indication Hypertension, angina

Action Blocks transport of calcium into muscle cells inhibiting excitation and contraction

Therapeutic Class Antihypertensive

Pharmacologic Class Ca channel blocker

Nursing Considerations • May cause gingival hyperplasia • Grapefruit juice may increase drug level • Monitor blood pressure and pulse prior to and during therapy • Monitor intake and output • Assess for signs of CHF • Assess characteristics of angina • Instruct patient of interventions for hypertension and how to take blood pressure

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name amoxicillin

Trade Name Moxatag

Indication skin infections, respiratory infections, sinusitis, endocarditis prophylaxis, lyme disease

Action Inhibits synthesis of bacterial cell wall leading to cell death.

Therapeutic Class anti-infectives, antiulcer agent

Pharmacologic Class aminopenicillins

Nursing Considerations • contraindicated with penicillin allergy • may cause seizures • assess for rash, anaphylaxis • excreted by kidneys – monitor renal labs • monitor patient for diarrhea – bloody stool should be reported immediately

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Generic Name Acetylsalicylic Acid

Trade Name Aspirin

Indication Rheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis

Action Inhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases

Therapeutic Class Antipyretics, non-opioid analgesics

Pharmacologic Class Salicylates

Nursing Considerations • Use caution in bleeding disorders, chronic alcohol use • May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis • Increases risk for bleeding with warfarin, heparin, and clopidogrel • Increased risk for GI bleeding with NSAID use • Monitor liver function tests • Concurrent use with alcohol may increase risk for GI bleeding • Aspirin with viral infections can cause Reye’s syndrome

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Generic Name Amlodipine

Trade Name Norvasc

Indication Hypertension, angina

Action Blocks transport of calcium into muscle cells inhibiting excitation and contraction

Therapeutic Class Antihypertensive

Pharmacologic Class Ca channel blocker

Nursing Considerations • May cause gingival hyperplasia • Grapefruit juice may increase drug level • Monitor blood pressure and pulse prior to and during therapy • Monitor intake and output • Assess for signs of CHF • Assess characteristics of angina • Instruct patient of interventions for hypertension and how to take blood pressure

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Ampicillin

Trade Name Principen

Indication Skin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia

Action Bactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death

Therapeutic Class Anti-infective

Pharmacologic Class Aminopenicillin

Nursing Considerations • Contraindicated in penicillin allergy, use caution in renal insufficiency • May lead to seizures, diarrhea, anaphylaxis, superinfection • Assess for infection • Monitor liver function tests • Instruct patient on signs of superinfection: furry overgrowth on tongue, vaginal itching, loose and foul smelling stool • Pt should not use with oral contraceptive use.

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Outline Generic Name Amitriptyline

Trade Name Elavil

Indication Depression, anxiety, insomnia, parkinson’s

Action Increases effect of serotonin and norepinephrine in the CNS, exhibits anticholinergic effects

Therapeutic Class Antidepressant

Pharmacologic Class Tricyclic antidepressant

Nursing Considerations • Contraindicated in MI, heart failure, QT prolongation, glaucoma • May increase risk for suicidal ideation • May cause arrhythmias, hypotension, EKG changes • May cause alterations in blood glucose levels • May lead to general sedation and lethargy • Do not use within 2 weeks of MAOIs • Instruct pt to take medication exactly as instructed • Monitor for orthostatic hypotension • May lead to photosensitivity, instruct patient to use sunscreen • May turn urine blue/green color.

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Visit https://nursing.com/140meds to request your free copy of "140 Must Know Meds"   Outline Generic Name Amiodarone

Trade Name Cordarone

Indication a-fib, ventricular arrhythmias, SVT, ACLS protocol for v-fib and v-tach

Action Prolongs phase 3 of the action potential, makes the heart more tolerant to arrhythmias, inhibits adrenergic stimulation, slows rate, decreases peripheral vascular resistance causing vasodilation

Therapeutic Class Antiarrhythmic class III, potassium channel blocker

Pharmacologic Class None

Nursing Considerations • May lead to ARDS, pulmonary toxicity, CHF, bradycardia, hypotension • Increases risk for QT prolongation • Increases digoxin levels • Increases activity of warfarin • Monitor EKG continuously while on therapy • Assess for signs and symptoms of ARDS • Monitor liver function test • Check dosage with another RN • Teach pt to monitor pulse daily and report abnormalities • Avoid drinking grapefruit juice

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Hey guys, let's talk about acyclovir. Also known as Zovirax, acyclovir comes in a tablet form, which you can see here in this picture, but also in a capsule, oral suspension IV, and even a topical ointment. Okay, guys, remember that the therapeutic class is what the drug does to the body and the pharmacologic class is the actual chemical effect that the drug has. So acyclovir is an antiviral medication that helps to slow the growth of viral infections in the body. The pharmacologic class of acyclovir is it is a purine analog, which, long story short, means it blocks the replication of the viral DNA. So, guys, the action of acyclovir is that it interferes with the viral DNA synthesis, meaning it stops the spread of the virus. Acyclovir is used to treat infections that are caused by the herpes virus, like genital or oral herpes, herpes, zoster, or shingles, and varicella, also known as chickenpox. Important: acyclovir will not cure the herpes virus; it only stops the growth and treats the symptoms. So side effects aren't super common with acyclovir, but the ones that we often see are an overall sense of malaise or fatigue, nausea, vomiting, and a headache. So guys remember to assess your patient for renal impairment or seizure disorders because acyclovir can make these issues worse. Use caution in immunocompromised. Patients' doses may need to be altered. Monitor the lesions to see if the treatment is working and remember to teach your patient to use protection with sexual intercourse, and to always take the full dose of the medication. Guys, I once had a patient in a clinic that was under the impression that they would be cured of general herpes after taking acyclovir. Remember to teach your patient that this medication will not cure only help the disease process. That's it for acyclovir or Zovirax. Now go out and be your best self today and as always happy nursing.

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Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Outline Generic Name Alprazolam

Trade Name Xanax

Indication Anxiety, panic disorder, manage symptoms of PMS, insomnia, mania, psychosis

Action Works in CNS to produce anxiolytic effect causing CNS depression.

Therapeutic Class Antianxiety agent

Pharmacologic Class Benzodiazepine

Nursing Considerations • Use caution with existing CNS depression, sleep apnea, renal dysfunction, hepatic dysfunction. • May cause CNS depression, drowsiness, lethargy • May lead to physical dependence, may experience tolerance effect • Assess anxiety and mental status • Romazicon (flumazenil) is the antidote for overdose • Grapefruit juice may increase blood levels

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Trade Name Fosamax

Indication Osteoporosis (aging, menopause, corticosteroid induced)

Action Inhibits osteoclast activity leading to inhibition of resorption of bone

Therapeutic Class Bone resorption inhibitor

Pharmacologic Class Bisphosphonates

Nursing Considerations • Take first thing in the morning with full glass of water 30 min prior to eating • Assess serum calcium and vitamin D • May lead to muscle pain

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Outline Generic Name Albuterol

Trade Name Proventil

Indication Bronchodilator used to prevent airway obstruction in asthma and COPD

Action Binds to Beta2 adrenergic receptors in the airway leading to relaxation of the smooth muscles in the airways

Therapeutic Class Bronchodilator

Pharmacologic Class Adrenergic

Nursing Considerations • May decrease the effectiveness of Beta Blockers • Use caution with ○ Heart disease ○ Diabetes ○ Glaucoma ○ Seizure disorder • Overuse of inhalers can lead to bronchospasm • Monitor for chest pain and palpitations • Can decrease digoxin levels

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Visit: https://nursing.com/140meds for your free+shipping 140 Meds book What is the Generic Name Acetaminophen

What is the Trade Name for Acetaminophen Tylenol

What is the Indication for Acetaminophen Pain, fever

What is the Action of Acetaminophen Inhibit the synthesis of prostaglandins which play a role in transmission of pain signals and fever response

What is the Therapeutic Class of Acetaminophen Antipyretic, non-opioid analgesic

What are the Nursing Considerations for Acetaminophen • Do not exceed 4g of acetaminophen per day to limit risk for liver, renal, and cardiac damage • Overdose will lead to hepatotoxicity • Acetadote is the antidote for overdose • May increase risk for bleed with warfarin therapy • May alter blood glucose measurements

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Download the cheat: https://bit.ly/50-meds  View the lesson:   Generic Name warfarin Trade Name Coumadin Indication venous thrombosis, pulmonary embolism, A-fib, myocardial infarction

Action disrupts liver synthesis of Vitamin K dependent clotting factors

Therapeutic Class Anticoagulant

Pharmacologic Class coumarins

Nursing Considerations • contraindicated with bleeding, severe hypertension • can cause bleeding • aspirin and NSAIDs can increase risk of bleeding • azole antifungals increase effects of warfarin • cimetadine(Tagamet) increases warfarin levels • obtain full history of supplements and herbs • large amounts of vitamin K may antagonize effects of warfarin • assess for signs of bleeding • therapeutic levels: PT 1.3-1.5, INR 2.5-3.5 • instruct patient to report any signs of bleeding • patient should not drink alcohol • bleeding times need to be monitored frequently • vitamin K is antidote

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name verapamil Trade Name Isoptin

Indication hypertension, angina, SVT, migraine

Action prevents transport of calcium, leading to decreased contraction, decreases SA and AV node conduction

Therapeutic Class antianginals, antiarrhythmic, antihypertensive, vascular headache suppressants

Pharmacologic Class Ca Channel Blocker

Nursing Considerations • don’t use with 2nd and 3rd degree heartblock • don’t use with systolic BP < 90 • may cause anxiety, confusion, cough, dyspnea, arrhythmias, CHF, bradycardia, hypotension, elevated liver enzymes, Steven’s Johnson syndrome, hyperglycemia, gingival hyperplasia • grapefruit juice can increase effects • can increase levels of digoxin • monitor heart rhythm, intake and output, blood pressure • assess angina

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name vasopressin Trade Name Pitressin

Indication management of diabetes insipidus, VT/VF unresponsive to initial shock, GI hemorrhage

Action increases water permeability of the kidney’s collecting duct and distal convoluted tubule leading to water retention, also increases peripheral vascular resistance leading to increased BP

Therapeutic Class hormone

Pharmacologic Class antidiuretic hormone

Nursing Considerations • use caution with HF and CV disease • contraindicated in renal failure and hypersensitivity to pork • monitor BP, HR, and EKG during therapy • monitor urine specific gravity and osmolality • weigh patient and assess for edema • monitor electrolyte panel • do not use with alcohol

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Generic Name vancomycin Trade Name Vancocin

Indication life threatening infections, sepsis

Action bactericidal, inhibits cell wall synthesis

Therapeutic Class anti-infectives

Pharmacologic Class glycopeptides

Nursing Considerations • can cause ototoxicity, nausea, vomiting, nephrotoxicity, anaphylaxis, red-man syndrome • assess for infection • obtain culture prior to initiating therapy • monitor blood pressure • dose dependent draw serum trough levels frequently • administer over at least 60 minutes to avoid skin irritation

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Generic Name metoprolol Trade Name Lopressor, Toprol XL

Indication tachyarrhythmias, HTN, angina, prevention of MI, heart failure management, may be used for migraine prophylaxis

Action blocks the stimulation of beta1 receptors in the SNS, does not usually effect on beta2 receptors (cardioselective)

Therapeutic Class antianginal, antihypertensive

Pharmacologic Class beta blocker

Nursing Considerations • monitor hemodynamics • may lead to bradycardia, pulmonary edema • use caution with MAOIs • assess I&Os and monitor for signs of CHF

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name tetracycline Trade Name Doxycycline

Indication treatment of infection, gonorrhea and syphilis with penicillin allergy, chronic bronchitis

Action bacteriostatic by inhibiting protein synthesis

Therapeutic Class anti-infectives

Pharmacologic Class Tetracyclines

Nursing Considerations • use caution with liver impairment • may cause pseudomembranous colitis, diarrhea, nausea, vomiting, photosensitivity, rash • may increase effects of warfarin • assess for infection • obtain culture prior to initiating therapy • monitor renal and liver labs • instruct patient to complete entire dose

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Generic Name terbutaline Trade Name Brethine, Brethaire

Indication asthma, COPD, preterm labor

Action produces smooth muscle relaxation, bronchodilator, and inhibits hypersensitivity reactions

Therapeutic Class bronchodilators

Pharmacologic Class adrenergics

tocolytics

Nursing Considerations • may cause nervousness, restlessness, tremors • beta blockers can reduce effect • assess respiratory status • monitor maternal/fetal vital signs if using for preterm labor • monitor for hypoglycemia • may cause decreased potassium level

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name Ferrous sulfate Trade Name Feosol

Indication Prevention and treatment of iron-deficiency anemia

Action Iron is essential for hemoglobin, myoglobin and enzymes, it is transported to organs where it becomes part of iron stores

Therapeutic Class Antianemics

Pharmacologic Class Iron supplements

Nursing Considerations • May cause seizures, hypotension, constipation, epigastric pain, diarrhea, skin staining, anaphylaxis • Assess nutritional status, bowel function • Monitor hemoglobin, hematocrit, iron levels • May cause elevated liver enzymes • Take on an empty stomach to increase absorption/vitamin c helps with absorption • Use z-track for IM injections

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Generic Name trimethoprim/sulfamethoxazole Trade Name Bactrim/TMP-SMZ Indication bronchitis, UTI, diarrhea, pneumonia, multiple types of infection

Action bacteriacidal by preventing metabolism of folic acid

Therapeutic Class anti-infectives, antiprotozoals

Pharmacologic Class folate antagonists, sulfonamides

Nursing Considerations • may cause renal damage, Steven Johnsons Syndrome – rash, pseudomembranous colitis, nausea, vomiting, diarrhea, rash, agranulocytosis, aplastic anemia, phlebitis • contraindicated with sulfa allergies • monitor CBC • obtain cultures prior to initiating therapy • monitor intake and output • instruct patient to complete dose • drink 8-10 glasses of water

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name sucralfate Trade Name Carafate

Indication management of GI ulcers, GI injury prevention from high dose aspirin and NSAID treatment

Action reacts with gastric acid to form a paste that adheres to ulcer

Therapeutic Class antiulcer agent

Pharmacologic Class GI protectant

Nursing Considerations • use caution in renal failure patients • concurrent use of antacids may decrease the effect of sucralfate – administer 30 min before or after • administer on empty stomach 1 hour before meals

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name streptokinase Trade Name Streptase

Indication pulmonary embolism, DVT, occluded lines, arterial thrombus

Action converts plasminogen to plasmin which degrades fibrin clots

Therapeutic Class Thrombolytic

Pharmacologic Class plasminogen activators

Nursing Considerations • contraindicated with active bleeding, hypersensitivity, bronchospasm, intracranial hemorrhage, hypotension • begin therapy as soon as possible • monitor vital signs continuously • monitor closely for bleeding • monitor hemodynamics • avoid invasive procedures

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name spironolactone Trade Name Aldactone

Indication potassium loss, hypertension, edema, CHF

Action inhibits sodium reabsorption while sparing potassium and hydrogen

Therapeutic Class Diuretics

Pharmacologic Class potassium sparing diuretics

Nursing Considerations • contraindicated with hyperkalemia • monitor intake and output • monitor blood pressure • monitor potassium levels and renal panel

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name sertraline Trade Name Zoloft

Indication major depressive disorder, OCD, anxiety

Action inhibits uptake of serotonin allowing for higher quantities available within synaptic cleft

Therapeutic Class Antidepressant

Pharmacologic Class SSRI

Nursing Considerations • do not use with MAOIs • can cause neurolyptic malignant syndrome, suicidal thoughts, drowsiness, insomnia, diarrhea, dry mouth, tremors, serotonin syndrome, sexual dysfunction • monitor mood changes in patient • takes 1-4 weeks for therapy to be effective.

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name salmeterol Trade Name Serevent Indication reversible airway obstruction, exercise induced asthma

Action bronchodilation through stimulation of beta 2 adrenergic receptors

Therapeutic Class bronchodilators

Pharmacologic Class adrenergics

Nursing Considerations • instruct patient to avoid excessive use • can cause headache palpitations tachycardia, abdominal pain, paradoxical bronchospasm • beta blockers and decrease effectiveness • assess respiratory status • may increase glucose levels • always take bronchodialtor first

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name rifampin Trade Name Rimactane

Indication tuberculosis

Action inhibits RNA synthesis

Therapeutic Class Antitubercular

Pharmacologic Class rifamycins

Nursing Considerations • can turn body fluids red • may cause diarrhea, nausea, vomiting, confusion • assess lung sounds and sputum characteristics • evaluate renal and liver function tests • instruct patient not to skip or double dose • must complete entire dose (6-12 month therapy)

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name ranitidine Trade Name Zantac

Indication duodenal ulcers, GERD, heartburn, esophagitis, GI bleed

Action inhibits action of histamine in gastric parietal cells, decreases gastric acid secretion

Therapeutic Class antiulcer agents

Pharmacologic Class histamine H2 antagonists

Nursing Considerations • may cause arrhythmias, agranulocytosis, aplastic anemia, confusion • assess abdominal pain • monitor for blood in stool • monitor CBC

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name quetiapine Trade Name Seroquel

Indication schizophrenia, depressive disorder, mania

Action dopamine and serotonin antagonist

Therapeutic Class antipsychotic, mood stabilizers

Pharmacologic Class none

Nursing Considerations • may cause neurolyptic malignant syndrome, seizures, dizziness, palpitations, weight gain, anorexia • QT interval prolongation • don’t use with CNS depressants • assess weight frequently • monitor liver function test and CBC • may increase cholesterol

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name propylthiouracil Trade Name PTU

Indication hyperthyroidism

Action inhibits thyroid hormones

Therapeutic Class Antithyroid Agent

Pharmacologic Class none

Nursing Considerations • hepatotoxicity, nausea, vomiting, agranulocytosis • monitor symptoms of hyperthyroidism • monitor for hypothyroidism • monitor WBC and liver function tests • weight patient frequently • may cause leukopenia, thrombocytopenia, jaundice • take with meals

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name propranolol Trade Name Inderal

Indication hypertension, angina, arrhythmias, cardiomyopathy, alcohol withdrawal, anxiety

Action blocks Beta 1 and 2 adrenergic receptors

Therapeutic Class antianginal, antiarrhythimic (class II beta blockers), antihypertensive, headache suppressant

Pharmacologic Class beta blocker

Nursing Considerations • contraindicated in CHF, pulmonary edema, cardiogenic shock, bradycardia, heart block • monitor hemodynamic parameters (HR, BP) • may cause bradycardia, CHF, pulmonary edema • masks symptoms of hypoglycemia associated with diabetes mellitus • advise to change positions slowly to prevent orthostatic hypotension • instruct patient on how to take blood pressure • stopping abruptly may result in life threatening arrhythmias • monitor daily intake and output • advise patient to notify physician for difficulty breathing

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name propofol Trade Name Diprivan

Indication anesthesia, induction, sedation,

Action hypnotic, produces amnesia with no analgesic properties

Therapeutic Class general anesthetic

Pharmacologic Class none

Nursing Considerations • use cautiously with CVD, lipid disorder, increased ICP • can cause apnea, bradycardia, hypotension • burning and pain at insertion site • can turn urine green • assess respiratory status and hemodynamics • maintain patent airway • assess level of sedation

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name Promethazine Trade Name Phenergan

Indication allergic reactions, nausea and vomiting, sedation

Action Blocks the effects of histamine, histamine plays a role in the immune response.  Plays an inhibitory role on the chemoreceptor trigger zone in the medulla leading to an antiemetic effect.  Possess anticholinergic properties producing CNS depression.

Therapeutic Class antiemetic, antihistamine, sedative/hypnotic

Pharmacologic Class phenothiazine

Nursing Considerations • IV administration may cause damage to tissue, hypertension, impaired liver function • monitor for neuroleptic malignant syndrome, confusion, sedation • may cause CNS depression • assess sedation level and anticholinergic effects

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name procainamide Indication wide variety ventricular and atrial arrhythmias, PAC, PVC, VTach, post cardioversion Action decreases excitability and slows conduction velocity through the heart

Therapeutic Class antiarrhythmic (Class IA Na Channel Blocker)

Nursing Considerations • may cause ventricular arrhythmias, seizure, asystole, heart block • monitor EKG continuously may cause widening of QRS complex • may cause hypotension keep patient supine • monitor for signs of agranulocytosis monitor CBC frequently • can cause drug induced lupus syndrome

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name phenytoin Trade Name Dilantin

Indication tonic clonic seizures, arrhythmias, neuropathic pain

Action interferes with ion transport, shortens action potentials and decreases automaticity blocks sustained high frequency repetitive firing of action potentials.

Therapeutic Class antiarrhythmics, anticonvulsants

Pharmacologic Class hydantoins

Nursing Considerations • monitor serum phenytoin levels • therapeutic levels 10-20 mcg/mL • use cautiously in all patients • can cause suicidal thoughts, ataxia, extrapyramidal symptoms, hypotension, tachycardia, arrhythmias, gingival hyperplasia, nausea, rash, drug induced hepatitis, agranulocytosis, Steven’s Johnson syndrome • concurrent administration of enteral feedings may decrease absorption • monitor for hypersensitivity • assess seizures • assess hemodynamics

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name phenazopyridine Trade Name Pyridium

Indication urological pain

Action provides analgesia to the urinary tract mucosa

Therapeutic Class nonopioid analgesics

Pharmacologic Class urinary tract analgesics

Nursing Considerations • will turn urine red or orange • may cause headache, vertigo, hepatic toxicity • monitor renal function

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name paroxetine Trade Name Paxil

Indication major depressive disorder, OCD, anxiety, PTSD

Action block reuptake of serotonin in CNS

Therapeutic Class antianxiety agent, antidepressant

Pharmacologic Class SSRI

Nursing Considerations • do not use with MAOIs • can cause neurolyptic malignant syndrome, suicidal thoughts, serotonin syndrome, constipation, diarrhea, insomnia • decrease effectiveness of digoxin • increase bleeding with warfarin • assess for suicidal thoughts

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name pantoprazole Trade Name Protonix Indication GERD, heartburn, reduce the risk of GI bleed in critically ill patients

Action prevents the transport of H ions into the gastric lumen by binding to gastric parietal cells, ↓ gastric acid production

Therapeutic Class antiulcer agents

Pharmacologic Class proton-pump inhibitors

Nursing Considerations • can cause hyperglycemia, abdominal pain • decreases absorption of certain drugs • may increase bleeding with warfarin • assess for occult blood • assess liver enzymes • assess symptoms of heart burn • administer slowly via IV push

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name Pancrelipase Trade Name Creon

Indication pancreatic insufficiency, ductal obstruction

Action replacement of pancreatic enzymes: lipase, amylase, protease

Therapeutic Class digestive agent

Pharmacologic Class pancreatic enzyme

Nursing Considerations • contraindicated with pig products allergy • can cause shortness of breath, nausea, diarrhea, rash • assess nutritional status • monitor for steatorrhea • may increase uric acid levels • instruct patient to follow diet • take with meals and snacks

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name oxytocin Trade Name Pitocin

Indication labor induction, postpartum bleeding

Action stimulates uterine smooth muscle

Therapeutic Class hormones

Pharmacologic Class oxytocics

Nursing Considerations • can cause ICH in fetus • can cause asphyxia in fetus • may cause coma and seizures in mother • may cause painful contractions • assess fetus • assess contractions • monitor blood pressure • assess maternal electrolytes • may cause uterine tetany

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name oxycodone Trade Name Oxycontin

Indication pain

Action binds to opiate receptors in CNS altering the perception and sensation of pain

Therapeutic Class Opioid Analgesic

Pharmacologic Class opioid agonists, opioid agonists/nonopioid, analgesic combinations

Nursing Considerations • may cause respiratory depression, constipation, confusion , sedation, hallucinations, urinary retention • use caution with increased intracranial pressure • don’t use with MAOIs • assess hemodynamics • assess pain • may elevate pancreatic enzymes • can cause physical dependence • assess bowel function

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Download the cheat: https://bit.ly/50-meds  View the lesson:     Generic Name ondansetron Trade Name Zofran

Indication nausea/vomiting

Action blocks effects of serotonin on vagal nerve and CNS

Therapeutic Class antiemetic

Pharmacologic Class 5-HT3 antagonist

Nursing Considerations • administer slowly over 2-5 minutes – fatal QT prolongation and VTach, respiratory arrest • may cause headache, constipation, diarrhea, dry mouth • asses nausea and vomiting • assess for extrapyramidal symptoms • monitor liver function tests

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Download the cheat: https://bit.ly/50-meds View the lesson: Generic Name omeprazole

Trade Name Prilosec

Indication GERD, ulcers, Zollinger-Ellison syndrome, reduce the risk of GI bleed in critically ill patients, heart burn

Action prevents the transport of H ions into the gastric lumen by binding to gastric parietal cells, ↓ gastric acid production

Therapeutic Class antiulcer agent

Pharmacologic Class proton-pump inhibitor

Nursing Considerations • take 30-60 minutes prior to eating
• capsules should be swallowed whole
• instruct patient to report black tarry stool

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Download the cheat: https://bit.ly/50-meds View the lesson: Generic Name olanzapine

Trade Name Zyprexa

Indication schizophrenia, mania, depression, anorexia nervosa, nausea/vomiting related to chemotherapy

Action antagonizes dopamine and serotonin

Therapeutic Class antipsychotic, mood stabilizers

Pharmacologic Class thienobenzodiazepines

Nursing Considerations • do not use while breastfeeding
• can cause neurolyptic malignant syndrome, seizures, suicidal thoughts, insomnia, tardive
dyskinesia, agranulocytosis, constipation, tremors
• assess mental status
• monitor hemodynamics
• assess blood sugars
• assess intake and output
• monitor liver function tests

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Download the cheat: https://bit.ly/50-meds View the lesson: Generic Name nystatin Trade Name Mycostatin

Indication candidiasis, denture stomatitis

Action causes leakage of fungal cell contents

Therapeutic Class Antifungal

Pharmacologic Class none

Nursing Considerations • may cause diarrhea, nausea, vomiting
• can be used to soak dentures
• assess mucus membrane

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/NorepinephrineLevophedNursingConsiderations   Generic Name norepinephrine

Trade Name Levophed

Indication treatment of severe hypotension and shock

Action increase blood pressure and cardiac output by stimulating alpha-adrenergic receptors in the blood vessels, demonstrates minor beta activity

Therapeutic Class vasopressor

Nursing Considerations * monitor BP continuously if possible or every couple of minutes * double check all concentrations with additional nurse * may result in rebound hypotension due to tissue ischemia when discontinued * monitor EKG and CVP * if patient is awake instruct them to report headaches, dizziness, or chest pain

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/NitroprussideNitropressNursingConsiderations   Generic Name nitroprusside

Trade Name Nitropress

Indication hypertensive crisis, cardiogenic shock

Action peripheral vasodilation of arteries and veins decreasing preload and afterload

Therapeutic Class antihypertensive

Pharmacologic Class vasodilator

Nursing Considerations • monitor HR, BP, and EKG continuously during therapy
• may cause cyanide toxicity
• sympathomimetics may decrease effectiveness
• PAOP monitoring may help with MI and CHF patients

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/NifedipineProcardiaNursingConsiderations   Generic Name nifedipine

Trade Name Procardia

Indication hypertension, angina, migraines, CHF

Action blocks calcium transport resulting in inhibition of contraction causing systemic vasodilatation

Therapeutic Class antianginals, antihypertensives

Pharmacologic Class Ca Channel Blocker

Nursing Considerations • use caution in heart block, decreased blood pressure
• don’t consume grapefruit juice while taking medication
• may cause arrhythmias
• may cause elevated liver function tests
• may cause gingival hyperplasia, Steven’s Johnson syndrome
• monitor blood pressure and pulse
• monitor calcium levels
• instruct patient on taking heart rate and blood pressure

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/NaproxenAleveNursingConsiderations   Generic Name naproxen

Trade Name Aleve

Indication pain, dysmenorrhea, fever, inflammation

Action inhibits prostaglandin synthesis

Therapeutic Class nonsteroidal anti-inflammatory agents, nonopioid analgesics, antipyretics

Pharmacologic Class none

Nursing Considerations • use caution with GI bleeding
• may increase risk for stroke and MI
• can cause GI bleeding, anaphylaxis, Steven’s Johnson syndrome
• aspirin can decrease blood levels and effectiveness
• assess pain
• patients should remain up-right for 30 minutes after administration

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/NalbuphineNubainNursingConsiderations   Generic Name nalbuphine

Trade Name Nubain

Indication pain, analgesia during labor, sedation before surgery, supplement to balance anesthesia

Action alters perception and response to pain, causes CNS depression

Therapeutic Class Opioid Analgesic

Pharmacologic Class opioid agonists/analgesics

Nursing Considerations • use caution with head trauma
• can cause dizziness, headache, nausea, vomiting, respiratory depression
• do not use with MAOIs
• assess pain
• may cause respiratory depression in newborn
• asses hemodynamic parameters
• may elevate pancreatic enzymes
• Narcan (naloxone) is the antidote

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MorphineMSContinNursingConsiderations   Generic Name morphine

Trade Name MS Contin

Indication pain, pulmonary edema, MI

Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.

Therapeutic Class opioid analgesic

Pharmacologic Class opioid agonist

Nursing Considerations • may cause alterations in mentation, hypotension, constipation, nausea, vomiting
• assess BP, pulse, and respiratory rate prior to administration and frequently during administration
• use caution if patient is receiving MAO Inhibitors
• Narcan (naloxone) is the antidote for opioid agonists

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MontelukastSingulairNursingConsiderations   Generic Name montelukast

Trade Name Singulair

Indication prevent or treat asthma, manage seasonal allergies, prevent exercise-induced bronchoconstriction

Action disrupts the effects of leukotrienes which effect airway edema, smooth muscle constriction, and cellular activity

Therapeutic Class allergy, cold, and cough remedies, bronchodilators

Pharmacologic Class Leukotriene Antagonist

Nursing Considerations • assess respiratory status
• assess liver function tests
• medication does not treat acute asthma attacks

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MidazolamVersedNursingConsiderations     Generic Name midazolam

Trade Name Versed

Indication sedation, conscious sedation, anesthesia, status epilepticus

Action acts to produce CNS depression, may be mediated by GABA

Therapeutic Class antianxiety agent, sedative/hypnotics

Pharmacologic Class Benzodiazepine

Nursing Considerations • assess level of sedation during and for 2-6 hours following
• monitor blood pressure, pulse, respirations during IV administration
• may lead to apnea, cardiac arrest, respiratory depression
• antidote for overdose is Romazicon (flumazenil)

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MetronidazoleFlagylNursingConsiderations   Generic Name metronidazole Trade Name Flagyl

Indication intra-abdominal infections, gynecoligical infections, skin infections, bone and joint infections, CNS
infections, septicemia, endocarditis, amebic liver abscess, peptic ulcer disease

Action Inhibits DNA and protein synthesis in bacteria, bactericidal

Therapeutic Class anti-infectives, antiprotozoals, antiulcer agents

Pharmacologic Class none

Nursing Considerations • do not take with alcohol-disulfiram reaction
• assess for infection before and during treatment
• obtain cultures before therapy
• monitor neurologic status: parasthesia, weakness, ataxia, or seizures
• monitor intake and output, daily weights
• may alter liver enzyme tests

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MetoclopramideReglanNursingConsiderations     Generic Name metoclopramide

Trade Name Reglan

Indication prevention of nausea, vomiting, hiccups, migraines, gastric stasis

Action accelerates gastric emptying by stimulating motility

Therapeutic Class antiemetic

Pharmacologic Class Dopamine D2 receptor antagonist, prokinetic

Nursing Considerations • do not use with GI obstruction
• may cause extrapyramidal reaction, neurolyptic malignant syndrome, tardive dyskinesia,
arrhythmias, blood pressure alterations, hematologic alterations, facial movements, sedation
• can decrease effects of levodopa
• assess nausea/vomiting
• monitor liver function tests

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MethylphenidateConcertaNursingConsiderations   Generic Name methylphenidate

Trade Name Ritalin, Concerta

Indication ADHD, narcolepsy

Action improves attention span in ADHD by producing CNS stimulation

Therapeutic Class central nervous system stimulant

Pharmacologic Class none

Nursing Considerations • can cause sudden death, hypertension, palpitations, anorexia, hyperactivity, insomnia
• may decrease effects of Warfarin and Phenytoin
• do not use with MAOIs
• monitor cardiovascular system
• monitor for behavioral changes
• monitor for dependence
• do not consume caffeinated beverages
“Drug Holiday” used to assess dependence and status

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MethylergonovineMethergineNursingConsiderations     Generic Name methylergonovine Trade Name Methergine

Indication treatment of post-partum hemorrhage

Action stimulates uterine muscles causing uterine contraction

Therapeutic Class oxytocic

Pharmacologic Class ergot alkaloids

Nursing Considerations • can cause hypertension, cramps, nausea, vomiting, dyspnea
• monitor BP, heart rate, uterine response
• assess calcium levels – effectiveness ↓ with hypocalcemia
• monitor uterine bleeding and notify physician of any changes

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MethadoneMethadoseNursingConsiderations   Generic Name methadone Trade Name Mathadose

Indication withdrawal symptoms, pain

Action Suppresses withdrawal symptoms. Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility.

Therapeutic Class opioid analgesic

Pharmacologic Class opioid agonist

Nursing Considerations • use caution if patient is receiving MAO Inhibitors
• may cause QT prolongation, hypotension, respiratory depression, dependence, confusion, sedation
• assess pain, vital signs, bowel function
• may increase pancreatic enzyme levels
• assess withdrawal symptoms

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MetforminGlucophageNursingConsiderations   Generic Name metformin

Trade Name Glucophage

Indication management of Type II DM, PCOS

Action decreases glucose production in the liver, decreases absorption, increases cellular insulin sensitivity

Therapeutic Class Antidiabetic

Pharmacologic Class Biguanide

Nursing Considerations • do not use with renal dysfunction, metabolic acidosis
• may cause diarrhea, nausea, vomiting, lactic acidosis
• monitor patient closely for ketoacidosis and lactic acidosis, discontinue medication immediately
if acidotic
• may cause metallic taste
• instruct patient that medication does not cure diabetes

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MeperidineDemerolNursingConsiderations   Generic Name meperidine

Trade Name Demerol

Indication moderate to severe pain, sedation

Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.

Therapeutic Class Opioid Analgesic

Pharmacologic Class opioid agonists

Nursing Considerations • may cause alterations in mentation, hypotension, constipation, nausea, vomiting
• assess BP, pulse, and respiratory rate prior to administration and frequently during
administration
• use caution if patient is receiving MAOIs
• Narcan (naloxone) is the antidote for opioid agonists
• can cause seizure
• may increase pancreatic enzyme levels
• assess bowel function

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MannitolOsmitrolNursingConsiderations   Generic Name mannitol

Trade Name Osmitrol

Indication increased ICP, oliguric renal failure, edema, increased intraocular pressure

Action inhibits reabsorption of water and electrolytes by increasing osmotic pressure, excreted by kidneys

Therapeutic Class diuretic

Pharmacologic Class osmotic diuretic

Nursing Considerations • may cause phlebitis at IV site
• may cause dehydration, fluid and electrolyte imbalances
• monitor neuro status
• administer via a filter

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/MagnesiumSulfateNursingConsiderations   Generic Name magnesium sulfate

Trade Name MgSO4

Indication treatment of hypomagnesaemia, hypertension, preterm labor, torsade de pointes, asthma, anticonvulsant with eclampsia

Action magnesium plays a role in muscle excitability

Therapeutic Class mineral and electrolyte replacements/supplements

Pharmacologic Class minerals/electrolytes

Nursing Considerations * use caution with renal insufficiency * may cause decreased respiratory rate, arrythmias, hypotension, muscle weakness * monitor EKG and respiratory status * monitor Mg levels * ensure dosage with secondary practitioner * Calcium gluconate is the antidote + Magnesium toxicity results in respiratory depression and loss of deep tendon reflexes

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LosartanCozaarNursingConsiderations     Generic Name losartan

Trade Name Cozaar

Indication hypertension, DM neuropathy, CHF

Action inhibits vasoconstrictive properties of angiotensin II

Therapeutic Class antihypertensives

Pharmacologic Class angiotensin II receptor antagonist

Nursing Considerations • may cause hypotension, tacycardia, angiodema, hyperkalemia
• may increase digoxin levels
• assess blood pressure and heart rate
• assess fluid levels
• monitor daily weights with CHF
• monitor renal and liver
• instruct patient on how to take blood pressure

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LorazepamAtivanNursingConsiderations     Generic Name lorazepam

Trade Name Ativan

Indication anxiety, sedation, seizures

Action general CNS depression by potentiating inhibitory neurotransmitters

Therapeutic Class anesthetic adjuncts, antianxiety agents, sedative hypnotics

Pharmacologic Class Benzodiazepine

Nursing Considerations • use caution with COPD and sleep apnea
• avoid alcohol use
• antidote is Flumazenil (Romazicon)
• may cause apnea, cardiac arrest, bradycardia, hypotension
• use caution with other CNS depressants
• administer slowly and dilute to decrease complications

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LoperamideImodiumNursingConsiderations     Generic Name loperamide

Trade Name Imodium

Indication acute diarrhea, decrease drainage post ileostomy

Action inhibits peristalsis, reduces the volume of feces while increasing the bulk and viscosity

Therapeutic Class antidiarrheal

Nursing Considerations • may lead to constipation – insure proper use
• assess bowel function
• assess fluid and electrolyte levels

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LithiumLithonateNursingConsiderations     Generic Name lithium

Trade Name Lithizine

Indication mania

Action alters cation transport and neurotransmitter reuptake

Therapeutic Class Mood Stabilizer

Pharmacologic Class none

Nursing Considerations • do not administer with NSAIDs
• monitor drug blood levels frequently
• may cause seizures, arrhythmias, fatigue, confusion, nausea, anorexia, hypothyroidism, tremors
• Ace Inhibitors may increase serum levels
• instruct patient to maintain adequate fluid intake
• therapeutic level: 0.5-1.5 mEq/L

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LisinoprilPrinivilNursingConsiderations     Generic Name lisinopril

Trade Name Prinivil

Indication hypertension, management of CHF

Action block conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone
leading to vasodilation

Therapeutic Class antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • dry cough
• first dose hypotension
• use cautiously with potassium supplements and potassium sparing diuretics
• use cautiously with diuretic therapy
• administer 1 hour before meals
• monitor blood pressure often
• monitor weight and fluid status
• monitor renal profile
• monitor liver function tests

• may cause angioedema

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Download the cheat: https://bit.ly/50-meds View the lesson:     Generic Name levofloxacin Trade Name Levaquin

Indication urinary tract infections, gonorrhea, respiratory tract infections, bronchitis, pneumonia, skin and bone
infections

Action inhibits DNA synthesis in bacteria

Therapeutic Class Anti-infective

Pharmacologic Class fluoroquinolone

Nursing Considerations • contraindicated in allergies
• may cause QT prolongation, avoid use with other drugs that can cause QT prolongation
• can cause seizures, arrhythmias, pseudomembranous colitis, anaphylaxis, Stevens Johnson
syndrome

• increases the risk for tendinitis or tendon rupture

• may decrease plasma concentration of phenytoin
• monitor renal panel
• assess for infection, obtain cultures prior to therapy
• monitor liver function tests

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LevodopaSinemetNursingConsiderations     Generic Name Carbidopa/levodopa

Trade Name Sinemet

Indication Parkinson’s disease

Action Levodopa is converted to dopamine and works as a neurotransmitter, carbidopa
prevents the destruction of levodopa allowing it to cross the blood brain barrier

Therapeutic Class Antiparkinson agent

Pharmacologic Class Dopamine Agonist

Nursing Considerations • May cause orthostatic hypotension
• May cause dark urine
• Weeks to months to take effect
• Do not use with MAOIs
• Do not use with glaucoma, melanoma
• Assess for parkinsonian symptoms
• Instruct patient to take as directed

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LevetiracetamKeppraNursingConsiderations     Generic Name levetiracetam

Trade Name Keppra

Indication Seizures

Action decreases severity and incidence of seizures by inhibiting presynaptic calcium channels and reducing neurotransmitter realease

Therapeutic Class anticonvulsants

Pharmacologic Class pyrrolidines

Nursing Considerations • May cause suicidal thoughts, dizziness, weakness
• May alter RBC, WBC, and liver function
• May cause somnolence
• Should be infused over 15 minutes

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/IodineNursingConsiderations     Generic Name radioactive iodine

Trade Name none

Indication thyroidectomy pretreatment, thyrotoxic crisis, radiation exposure

Action inhibits the release of thyroid hormones

Therapeutic Class Antithyroid Agent, control of hyperthyroidism

Pharmacologic Class none

Nursing Considerations • may cause GI bleeding, diarrhea, hypothyroidism, goiter
• monitor for hypersensitivity

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/HeparinHep-LockNursingConsiderations     Generic Name heparin

Trade Name Hep-Lock

Indication Venous thromboembolism prophylaxis and treatment, low dose used to ensure patency of IV catheters

Action increases the inhibitory effect of antithrombin on factor Xa

Therapeutic Class anticoagulant

Pharmacologic Class antithrombotic

Nursing Considerations • monitor for signs of bleeding
• monitor platelet count
• may cause hyperkalemia
• have patient report any signs of bleeding

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LamotrigineLamictalNursingConsiderations     Generic Name lamotrigine

Trade Name Lamictal

Indication seizures r/t epilepsy, bipolar

Action Inhibits sodium transport in neurons

Therapeutic Class anticonvulsant

Nursing Considerations • may cause suicidal thoughts, dizziness, behavior changes, nausea, vomiting, photosensitivity,
rash, Stevens-Johnson Syndrome
• use caution with oral contraceptive use
• assess mental status
• assess for seizures
• do not discontinue use abruptly

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/LactuloseGenerlacNursingConsiderations     Generic Name lactulose

Trade Name Kristalose

Indication Constipation, portal-systemic encephalopathy

Action draws water into the stool and softens stool, inhibits ammonia passing into the colon

Therapeutic Class laxative

Pharmacologic Class osmotic

Nursing Considerations • use caution with DM
• may cause cramps, abdominal distention, hyperglycemia
• assess mental status, ammonia levels, abdominal distention
• patient should average 2-3 bowel movements per day

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/KetorolacToradolNursingConsiderations     Generic Name ketorolac

Trade Name Toradol

Indication pain

Action pain relief due to prostaglandin inhibition by blocking of the enzyme cyclooxygenase (COX)

Therapeutic Class nonsteroidal anti-inflammatory agents, nonopioid analgesics

Pharmacologic Class pyrroziline carboxylic acid

Nursing Considerations • may cause GI bleeding, Stevens-Johnson Syndrome, anaphylaxis, drowsiness
• should not exceed 5 days of therapy
• bleeding risk increased with garlic, ginger, and ginkgo
• may decrease effectiveness of hypertensive medications and diuretics

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/IsoniazidNiazidNursingConsiderations   Generic Name isoniazide

Trade Name INH

Indication tuberculosis

Action Inhibits synthesis of mycobacterial cell wall

Therapeutic Class Antitubercular

Pharmacologic Class none

Nursing Considerations • can cause jaundice
• may cause peripheral neuropathy, seizures, hepatitis
• patient should avoid high amounts of tyramine (pickled meats, aged/smoked meats, alcohol, exotic/aged cheese)
• monitor liver function tests
• complete full course of therapy (6-12 months)
• often used in combination with Rifampin

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/IndomethacinIndocinNursingConsiderations   Generic Name indomethacin

Trade Name Indocin

Indication Inflammatory disorders when patients do not respond to other medications

Action Decreases pain and inflammation by inhibiting prostaglandin synthesis

Therapeutic Class antirheumatics, ductus arteriosus patency adjuncts (IV only), nonsteroidal anti-inflammatory agents

Pharmacologic Class none

Nursing Considerations • monitor for hepatitis and GI bleeding
• monitor for dizziness, drowsiness, and headache
• assess for anaphylactic reaction
• aspirin may decrease effectiveness
• monitor renal labs
• shake suspension before administration
• patient should wear sunscreen and protective clothing to protect against photosensitivity

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/IbuprofenMotrinNursingConsiderations   Generic Name ibuprofen

Trade Name Advil / Motrin

Indication Mild to moderate pain, inflammatory states

Action Decreases pain and inflammation by inhibiting prostaglandins

Therapeutic Class antipyretics, antirheumatics, nonopioid analgesics, nonsteroidal anti-inflammatory agents

Pharmacologic Class nonopioid analgesics

Nursing Considerations • may cause GI bleeding, hepatitis, Stevens-Johnson Syndrome
• may cause anaphylaxis
• monitor for headache, nausea, vomiting, constipation
• therapy should be discontinued after first sign of rash
• monitor renal and liver labs
• patient should avoid using alcohol

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/HydromorphoneDilaudidNursingConsiderations   Generic Name hydromorphone

Trade Name Dilaudid

Indication moderate to severe pain

Action alters the perception and reaction to pain by binding to opiate receptors in the CNS, also suppresses the cough reflex

Therapeutic Class Opioid Analgesic, allergy, cold and cough remedies, antitussive

Pharmacologic Class opioid agonist

Nursing Considerations • Assess BP, respirations, and pulse before and during administration – medication causes general
CNS depression
• Narcan (nalaxone) is the antidote for overdose
• use caution with concurrent use of MAOI – avoid use within 14 days of each other
• may be used as an antitussive
• advised to dilute with NS prior to administration and to administer slowly to decrease CNS
depression

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/HydrochlorothiazideHydrodiurilNursingConsiderations   Generic Name hydrochlorothiazide

Trade Name HydroDiuril

Indication Hypertension, CHF, renal dysfunction, cirrhosis, glucocorticoid therapy

Action Increases sodium and water excretion and produces arterial vasodilation

Therapeutic Class antihypertensives, diuretics

Pharmacologic Class thiazide diuretics

Nursing Considerations • May cause dizziness, hypokalemia, hyponatremia, hypophosphatemia, hypomagnesemia,
dehydration
• Hypokalemia can increase risk for digoxin toxicity
• Monitor blood pressure and intake and output
• Monitor electrolyte levels
• Patient should take medication at the same time each day even if feeling better
• Instruct patient on how to take blood pressure

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/HydralazineApresolineNursingConsiderations   Generic Name hydralazine

Trade Name Apresoline

Indication hypertension

Action arterial vasodilation by unclarified mechanism

Therapeutic Class anti-hypertensive

Pharmacologic Class vasodilator

Nursing Considerations • may cause tachycardia, sodium retention, arrhythmias, angina
• use caution with MAOIs
• monitor blood pressure
• instruct patient on how to take blood pressure

View Details

Download the cheat: https://bit.ly/50-meds View the lesson:  https://bit.ly/HaloperidolHaldolNursingConsiderations   Generic Name haloperidol

Trade Name Haldol

Indication Schizophrenia, mania, aggressive and agitated patient

Action Alters the effect of dopamine

Therapeutic Class Antipsychotic

Pharmacologic Class butyrophenones

Nursing Considerations • extrapyramidal symptoms, tardive dyskinesia
• use caution in QT prolongation
• may cause seizures, constipation, dry mouth, agranulosytosis
• assess for hallucinations
• monitor hemodynamics
• monitor for neuroleptic malignant syndrome (fever, muscular rigidity, altered mental status, and
autonomic dysfunction)
• monitor CBC with differential

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GuaifenesinMucinexNursingConsiderations   Generic Name guaifenesin

Trade Name Mucinex

Indication Cough suppression, expectorant

Action Decreases viscosity of and mobilizes secretions

Therapeutic Class allergy, cold and cough remedies, expectorant

Pharmacologic Class none

Nursing Considerations • patient should avoid over the counter cold medications
• assess lung sounds
• maintain adequate fluid intake

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GlucagonGlucagenNursingConsiderations   Generic Name glucagon

Trade Name GlucaGen

Indication severe hypoglycemia, antidote for beta blockers and calcium channel blockers

Action stimulates production of glucose from stores, relaxes GI tract

Therapeutic Class hormones

Pharmacologic Class pancreatics

Nursing Considerations • may cause anaphylaxis
• may cause hypotension
• assess for signs of hypoglycemia, neuro status
• monitor serum glucose levels
• teach patient signs of hypoglycemia

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GlipizideGlucotrolNursingConsiderations   Generic Name Glipizide

Trade Name Glucotrol

Indication Type 2 diabetes mellitus

Action Stimulates release of insulin from the beta cells in the pancreases and leads to increased sensitivity to insulin

Therapeutic Class Anti-diabetic

Pharmacologic Class Sulfonylureas

Nursing Considerations • May cause aplastic anemias, hypoglycemia, photosensitivity, dizziness,
drowsiness, headache, diarrhea
• Monitor CBC, assess for allergy to sulfonamides
• Beta blockers may increase signs of hypoglycemia
• Instruct patient on how to check blood sugars and
• Instruct patient on importance of carrying source of sugar in case of
hypoglycemia

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GentamicinGaramycinNursingConsiderations   Generic Name Gentamicin

Trade Name Cidomycin

Indication Treatment of gram negative infections when penicillin is ineffective

Action Inhibits bacterial protein synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Aminoglycoside

Nursing Considerations • Causes tinnitus-hearing loss/do not administer with penicillin
• Use caution in renal impairment
• Assess for infection
• Obtain cultures prior to therapy
• Monitor liver function tests
• Monitor blood levels of drug

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/GabapentinNeurontinNursingConsiderations   Generic Name Gabapentin

Trade Name Neurontin

Indication Seizures, peripheral neuropathy, neuropathic pain, prevention of migraines

Action Exact method of action unknown, may play a role in stabilizing neural membranes

Therapeutic Class Analgesic adjuncts, anticonvulsants, mood stabilizers

Pharmacologic Class None

Nursing Considerations • May cause suicidal thoughts, confusion, depression, drowsiness, ataxia, facial
edema, hypertension
• Monitor pt closely for changes in behavior and depression
• Assess seizure activity
• Assess pain level
• Patient should take medications exactly as prescribed

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/FurosemideLasixNursingConsiderations   Generic Name Furosemide

Trade Name Lasix

Indication Edema, hypertension

Action Prevents reabsorption of sodium and chloride in the kidneys, increase excretion of
water, sodium, chloride, magnesium, potassium

Therapeutic Class Diuretics

Pharmacologic Class Loop diuretics

Nursing Considerations • Use caution with liver disease
• May cause hypotension, dry mouth, excessive urination, dehydration,
electrolyte abnormalities, metabolic alkalosis
• Hypokalemia may lead to increase risk of digoxin toxicity
• Monitor renal panel
• Use caution with other antihypertensives
• Causes arthritic symptoms/do not administer with aminoglycosides due to
ototoxicity

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/FluticasoneFlonaseNursingConsiderations   Generic Name Fluticasone

Trade Name Flovent, Flonase

Indication prophylactic asthma treatment

Action locally acting anti-inflammatory

Therapeutic Class antiasthmatics, anti-inflammatory (steroid)

Pharmacologic Class Corticosteroids, Inhalation

Nursing Considerations • use cautiously with untreated infections and suppressed immune function
• may cause headache, insomnia, bronchospasm, nasal congestion, adrenal suppression
• monitor patient’s respiratory status
• may lead to decreased bone density
• instruct patients using corticosteroids and bronchodilators that they need to use
bronchodilators first.
• instruct patient to stop smoking

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/FluoxetineProzacNursingConsiderations   Generic Name Fluoxetine

Trade Name Prozac

Indication Depressive disorder, OCD, bulimia, panic disorder, bipolar, anorexia, ADHD, DM
neuropathy, obesity

Action Inhibits reuptake of serotonin allowing it to persist longer in the synaptic cleft

Therapeutic Class Antidepressant

Pharmacologic Class SSRI

Nursing Considerations • Do not use while taking MAOIs
• May cause suicidal thoughts, drowsiness, anxiety, sexual dysfunction,
insomnia, palpitations
• Monitor closely for serotonin syndrome
• Concurrent use with certain medications may lead to QT prolongation
• Monitor mood changes and assess for suicidal ideation
• Monitor nutrition status
• May cause elevated liver enzymes
• Instruct pt to maintain good oral hygiene

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/FentanylDuragesicNursingConsiderations   Generic Name Fentanyl

Trade Name Sublimaze

Indication Supplement to general anesthesia, continuous IV infusion for purpose of analgesia

Action Binds to opiate receptors in CNS altering perception of pain, producing CNS
depression

Therapeutic Class Opioid Analgesic

Pharmacologic Class Opioid agonists

Nursing Considerations • Use caution with increased ICP, head trauma, adrenal insufficiency
• Avoid use with MAOIs
• May cause apnea, laryngospasm, decreased respirations, bradycardia,
hypotension
• Do not consume grapefruit while taking this medication
• Monitor hemodynamics during administration
• Assess patient pain scale frequently

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/FamotidinePepcidNursingConsiderations   Generic Name Famotidine

Trade Name Pepcid

Indication Short term treatment of active ulcer, GERD, treatment of heartburn, indigestion,
management of Zollinger Ellison syndrome, prevention of GI bleeding in critically
ill patients, management of symptoms associated with overuse of NSAIDs

Action Blocks action of histamine located in gastric parietal cells, inhibits gastric acid
secretion

Therapeutic Class Antiulcer agent

Pharmacologic Class Histamine H2 antagonist

Nursing Considerations • May cause arrhythmias, agranulocytosis, aplastic anemias
• Assess for abdominal pain and occult blood
• Monitor CBC
• Instruct pt to increase fluid and fiber intake to prevent constipation

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/EscitalopramLexaproNursingConsiderations   Generic Name Escitalopram

Trade Name Lexapro

Indication Major depressive disorder, anxiety disorder, PCD, PTSD, social phobia

Action Increases the extracellular levels of serotonin in the synaptic cleft by selectively
inhibiting its reuptake

Therapeutic Class Antidepressant

Pharmacologic Class SSRI

Nursing Considerations • Contraindicated with MAOI
• May cause suicidal thoughts, insomnia, drowsiness, diarrhea, nausea,
serotonin syndrome
• May cause QT prolongation with certain medications
• Assess for sexual dysfunction
• May take 4-6 weeks for full affect to take place
• Monitor for serotonin syndrome (mental changes, NV, tachycardia,
hyperthermia)

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/ErythromycinErythrocinNursingConsiderations   Generic Name Erythromycin

Trade Name E-Mycin

Indication Useful in place of penicillin when patient cannot take penicillin, upper and lower
respiratory tract infections, otitis media, skin infections, pertussis, syphilis,
rheumatic fever

Action Bacteriostatic: suppresses bacterial protein synthesis

Therapeutic Class Anti-infective

Pharmacologic Class Macrolide

Nursing Considerations • Causes QT prolongation, ventricular arrhythmias
• Diarrhea
• Asses infection
• Monitor liver function tests
• Instruct patient to finish medication dosage even if they are feeling better
• Medication should not be shared

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/EpoetinEpogenNursingConsiderations Generic Name Epoetin

Trade Name Epogen

Indication Anemia

Action Stimulates erythropoiesis (production of RBCs)

Therapeutic Class Antianemic

Pharmacologic Class Hormones

Nursing Considerations * Assess dialysis shunts * Contraindicated in albumin hypersensitivity * May cause

+ Seizures
+ CHF
+ MI
+ CVA
+ Hypertension
  • Do not shake vial
  • Initiate seizure precautions
  • Monitor

    • Bleeding times
    • Signs of anemia

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/EpinephrineEpiPenNursingConsiderations Generic Name Epinephrine

Trade Name Adrenalin, EpiPen

Indication Asthma and COPD exacerbations, allergic reactions, cardiac arrest, anesthesia adjunct

Action Affects both beta1 and beta2 also has alpha agonist properties resulting in bron-
chodilation and increases in HR and BP. Inhibits hypersensitivity reactions.

Therapeutic Class Antiasthmatic, bronchodilator, vasopressor

Pharmacologic Class Adrenergic agonist

Nursing Considerations • Side effects include: angina, tachycardia, hypertension, restlessness,
nervousness, hyperglycemia
• Use with MAOI may lead to hypertensive crisis
• Patients should not use stimulants (caffeine, guarana, etc)
• Excessive use may cause bronchospasm
• Assess lung sounds, pulse, BP, and other hemodynamic parameters
• Monitor for chest pain
• Instruct patient to use as directed
• Patient should insure adequate fluid intake to liquefy secretions
• Mouth should be rinsed after inhalation
• Beta blockers may negate effects
• May increase blood glucose levels

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/EnoxaparinLovenoxNursingConsiderations   Generic Name Enoxaparin Trade Name Lovenox

Indication Prevention of VTE, DVT, and PE

Action Prevents thrombus formation by potentiating the inhibitory effect of antithrom-
bin on factor Xa and thrombin. Enoxaparin is a low molecular weight heparin.

Therapeutic Class Anticoagulant

Pharmacologic Class Antithrombotic

Nursing Considerations • Contraindicated in pork hypersensitivity
• Monitor for signs of bleeding
• Administer in subcutaneous tissue
• DO NOT eject air bubble prior to injection
• DO NOT aspirate or massage site

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/EnalaprilVasotecNursingConsiderations   Generic Name Enalapril

Trade Name Vasotec

Indication hypertension, management of CHF

Action Block conversion of angiotensin I to angiotensin II, increases renin levels and
decreases aldosterone leading to vasodilation

Therapeutic Class Antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • May cause hypersensitivity (allergic) reactions and angioedema (swelling of face, lips, tongue, throat)

• Can cause neutropenia – check WBCs regularly

• Use cautiously with potassium supplements and potassium sparing diuretics.
• Use cautiously with diuretic therapy
• Administer 1 hour before meals
• Monitor blood pressure often
• Monitor weight and fluid status
• Monitor renal profile
• Monitor CBC frequently
• Dry cough

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DopamineInotropinNursingConsiderations   Generic Name dopamine

Trade Name Inotropin

What is the indication for Dopamine? used to improve blood pressure, cardiac output, and urine output

Action Smaller doses result in renal vasodilation
Doses 2-10mcg/kg/min result in cardiac stimulation by acting on beta1 receptors
Doses >10mcg/kg/min stimulate alpha receptors leading to vasoconstriction (↑SVR)

What is the therapeutic class for Dopamine? inotropic, vasopressor

Pharmacologic Class adrenergic

Nursing Considerations for Dopamine (Inotropin) • Monitor hemodynamics closely: BP, HR, EKG, CVP, and PAOP if available
• Obtain parameters for hemodynamic values
• Titrate to obtain appropriate BP (more potent vasoconstrictors may be required)
• Irritation may occur at IV site
• Beta blockers may counteract therapeutic effects

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DobutamineDobutrexNursingConsiderations   Generic Name Dobutamine

Trade Name Dobutrex

Indication Short term management of heart failure

Action Dobutamine has a positive inotropic effect (increases cardiac output) with very
little effect on heart rate. Stimulates Beta1 receptors in the heart.

Therapeutic Class Inotropic

Pharmacologic Class Beta-adrenergic agonist

Nursing Considerations • Monitor hemodynamics: hypertension, ↑HR, PVCs
• Skin reactions may occur with hypersensitivity
• Beta blockers may negate therapeutic effects of dobutamine
• Monitor cardiac output
• Monitor peripheral pulses before, during, and after therapy
• DO NOT confuse dobutamine with dopamine

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DivalproexDepakoteNursingConsiderations   Generic Name Divalproex

Trade Name Depakote

Indication Seizures, manic episodes, prevention of headache

Action Increases the level of GABA (inhibitory neurotransmitter) in CNS

Therapeutic Class Anticonvulsant, vascular headache suppressants

Pharmacologic Class None

Nursing Considerations • May cause suicidal thoughts, agitation, dizziness, insomnia, hepatotoxicity,
pancreatitis
• Increases risk for bleeding with Warfarin
• Use caution with MAOIs
• Monitor liver function tests

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DiphenhydramineBenadrylNursingConsiderations   Generic Name Diphenhydramine

Trade Name Benadryl

Indication Allergy, anaphylaxis, sedation, motion sickness, antitussive

Action Antagonizes effects of histamine, CNS depression

Therapeutic Class Allergy, cold and cough remedy, antihistamine, antitussive

Pharmacologic Class Antihistamine

Nursing Considerations • May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick
secretions, hypotension, blurred vision, headache
• Anticholinergic effects (dry mouth, blurred vision, constipation, sedation)
• Assess purpose of medication prior to giving it
• Assess allergies, sleep patterns, cough and lung sounds
• Patient should avoid other over-the-counter cough and cold remedies

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DiltiazemCardizemNursingConsiderations   Generic Name Diltiazem

Trade Name Cardizem

Indication Hypertension, angina, SVT, AFib, aflutter

Action Inhibits calcium transport resulting in inhibition of excitation and contraction,
leads to depression of AV and SA node leading to decreased HR, leads to vasodi-
latation and decreased blood pressure.

Therapeutic Class Antianginals, antiarrhythmics, antihypertensive

Pharmacologic Class Ca Channel Blocker (Benzothiazepine)

Nursing Considerations • Contraindicated in 2nd and 3rd AV block
• May cause arrhythmias, CHF, bradycardia, peripheral edema, gingival
hyperplasia
• Increases digoxin levels
• Don’t drink grapefruit juice
• Assess for signs of CHF
• Monitor EKG continuously
• Tell patient to change positions slowly
• Monitor serum potassium
• Instruct pt on how to take blood pressure

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DigoxinLanoxinNursingConsiderations   Generic Name Digoxin

Trade Name Lanoxin

Indication CHF, AFib, A-flutter

Action Positive inotropic effect (increases force of myocardial contraction), prolongs
refractory period, ↓ conduction through SA and AV nodes. Essentially digoxin is
given to increase cardiac output and slow the rate.

Therapeutic Class Antiarrhythmic, inotropics

Pharmacologic Class Digitalis glycosides

Nursing Considerations • Excreted by kidneys
• Assess patient for hypersensitivity
• Contraindicated with uncontrolled ventricular arrhythmias
• Hypokalemia increase risk for toxicity
• Hypercalcemia ↑ risk for toxicity
• Use caution with diuretic use as they may cause electrolyte abnormalities
that can lead to toxicity
• Assess patient for cardiac arrhythmias including bradycardia
• Signs of toxicity include vision changes (blurred vision, yellow, green vision
disturbances)
• Monitor pulse rate for 1 full minute prior to dosing patient (hold for pulse <60)

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DiazepamValiumNursingConsiderations   Generic Name Diazepam

Trade Name Valium

Indication Anxiety, pre-op sedation, conscious sedation, treatment of seizures, insomnia,
management of alcohol withdrawal

Action Decreases the effects of voltage gated sodium channels to depresses the CNS

Therapeutic Class Antianxiety agents, anticonvulsants, sedative/hypnotics, skeletal muscle relax-
ants (centrally acting)

Pharmacologic Class Benzodiazepine

Nursing Considerations • Contraindicated in hepatic dysfunction
• Use caution with renal impairment
• Can cause dizziness, drowsiness, lethargy, hypotension, physical depen-
dence, tolerance
• Instruct patient to take as directed
• Caution to avoid alcohol use
• Flumazenil (Romazicon) is the reversal agent

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DexamethasoneDecadronNursingConsiderations   Generic Name Dexamethasone

Trade Name Decadron

Indication Manage cerebral edema, assess for Cushing’s Disease

Action Suppress inflammation and normal immune response. Used in inflammatory states
to decrease inflammation.

Therapeutic Class Antiasthmatics, corticosteroids

Pharmacologic Class Corticosteroids

Nursing Considerations • Excreted by the liver – monitor liver profile
• Avoid in active untreated infections
• May cause CNS alterations
• May cause peptic ulcers
• May cause Cushingoid appearance (buffalo hump, moon face)
• Weight gain
• Osteoporosis
• Decrease wound healing
• May elevate blood sugars
• May increase cholesterol and lipid values

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CyclosporineSandimmuneNursingConsiderations   Generic Name Cyclosporine

Trade Name Sandimmune

Indication Prevention of rejection in transplantation, treatment of severe RA, management
of ulcerative colitis

Action Inhibits normal immune response primarily by decreasing the activity of T cells

Therapeutic Class Immunosuppressant, antirheumatics (DMARD)

Pharmacologic Class Polypeptides (cyclic)

Nursing Considerations • May cause seizures, tremors, hypertension, hepatotoxicity, diarrhea, N/V,
gingival hyperplasia
• Increases immune suppression with corticosteroids
• Avoid grapefruit juice while taking this medications
• Assess for signs of organ rejection
• Monitor renal panel, liver enzymes
• Take medication as directed
• Lifelong therapy required for transplant patients
• Instruct pt on how to take blood pressure

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CortisoneCortoneNursingConsiderations   Generic Name Cortisone

Trade Name Cortone

Indication Management of adrenocortical insufficiency (Addison’s Disease). Replace cortisol
in states of deficiency, suppress inflammation and normal immune response.

Action The adrenal glands sit on top of the kidneys.
The adrenal glands excrete steroid hormones, including cortisol that play a role in
increasing blood sugars, immune suppression, and metabolism of fat, protein, and
carbohydrates, as well as decreasing bone formation.

Therapeutic Class Antiasthmatics, corticosteroids

Pharmacologic Class Corticosteroids

Nursing Considerations • Excreted by the liver – monitor liver profile
• Avoid in active untreated infections
• May cause CNS alterations
• May cause peptic ulcers
• May cause Cushingoid appearance (buffalo hump, moon face)
• Weight gain
• Osteoporosis
• Decrease wound healing
• May elevate blood sugars
• May increase cholesterol and lipid values

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CodeinePaveralNursingConsiderations   Generic Name Codeine

Trade Name Paveral

Indication Management of pain, diarrhea, cough suppressant

Action Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility.

Therapeutic Class Allergy, cold, cough remedy, antitussive, opioid analgesic

Pharmacologic Class Opioid agonist

Nursing Considerations • May cause alterations in mentation, hypotension, constipation, nausea,
vomiting
• Assess BP, pulse, and respiratory rate prior to administration and frequently
during administration
• Use caution if patient is receiving MAO Inhibitors
• Narcan (naloxone) is the antidote for opioid agonists

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/ClopidogrelPlavixNursingConsiderations   Generic Name Clopidogrel Trade Name Plavix

Indication Atherosclerotic events, MI, CVA, PVD, acute coronary syndrome

Action Inhibits platelet aggregation

Therapeutic Class Antiplatelet agent

Pharmacologic Class Platelet aggregation inhibitors

Nursing Considerations • May cause GI bleeding, neutropenia, hypercholesterolemia
• May increase risk for bleeding in warfarin, aspirin, heparin
• Can increase risk for bleeding with garlic, ginkgo, ginger
• Monitor for signs of bleeding
• Monitor bleeding times
• Monitor CBC and platelet count
• Discontinue use 5-7 days before surgery

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/ClindamycinCleocinNursingConsiderations   Generic Name Clindamycin

Trade Name Cleocin

Indication Skin infections, respiratory tract infections, septicemia, intra-abdominal infections,
osteomyelitis

Action Bacteriostatic: inhibits protein synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Lincosamide

Nursing Considerations • Arrhythmias, pseudomembranous colitis, diarrhea, phlebitis
• Monitor bowel function
• Assess for infection, obtain cultures prior to therapy
• Monitor liver function tests
• Monitor CBC

View Details

Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CiprofloxacinCiproNursingConsiderations   Generic Name Ciprofloxacin

Trade Name Cipro

Indication Urinary tract infections, gonorrhea, respiratory tract infections, bronchitis,
pneumonia, skin and bone infections, infectious diarrhea, abdominal infections

Action Inhibits bacterial DNA synthesis

Therapeutic Class Anti-infectives

Pharmacologic Class Fluoroquinolone

Nursing Considerations • Contraindicated in allergies
• May cause QT prolongation, avoid use with other drugs that can cause QT
prolongation
• Can cause seizures, arrhythmias, pseudomembranous colitis, anaphylaxis,
Stevens Johnson syndrome
• May decrease effects of phenytoin
• Monitor renal panel
• Assess for infection, obtain cultures prior to therapy
• Monitor liver function tests

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CimetidineTagametNursingConsiderations   Generic Name Cimetidine Trade Name Tagamet

Indication Treatment of duodenal ulcers, GERD, heartburn, Zollinger Ellison syndrome,
prevention of GI bleeding in critical patients.

Action Inhibits action of histamine leading to inhibition of gastric acid secretion

Therapeutic Class Antiulcer agent

Pharmacologic Class Histamine H2 antagonist

Nursing Considerations • Increases serum level of warfarin
• Can lead to respiratory infection (green sputum)
• Monitor for arrhythmias
• May cause agranulocytosis, aplastic anemia
• Monitor CBC during therapy
• Take medication as directed
• Instruct patient to increase fluid and fiber intake to decrease constipation

View Details

Download the cheat: https://bit.ly/50-meds View the lesson:   Generic Name Chlorpromazine

Trade Name Thorazine

Indication Second line treatment of schizophrenia and psychosis, nausea/vomiting, pre-op
sedation, acute intermittent porphyria, headache, bipolar

Action Exhibits anticholinergic activity, alters effects of dopamine in CNS

Therapeutic Class Antipsychotic, antiemetic

Pharmacologic Class Phenothiazines (dopamine D2 receptor antagonist)

Nursing Considerations • May cause neuroleptic malignant syndrome, sedation, tardive dyskinesia,
hypotension, agranulocytosis
• Assess mental status prior to and during treatment
• Monitor blood pressure
• Ensure patient is taking medication
• Monitor CBC and liver function tests
• Instruct patient not to skip doses or double dose.

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CephalexinKeflexNursingConsiderations   Generic Name Cephalexin

Trade Name Keflex

Indication Skin infections, pneumonia, UTI, otitis media

Action Bactericidal: binds to bacterial cell wall leading to cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 1st generation

Nursing Considerations • Contraindicated with cephalosporin and serious penicillin allergies.
• May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis
at IV site, anaphylaxis
• Assess infection and allergies
• Obtain cultures prior to therapy
• Monitor bowel function
• May lead to superinfection
• May cause elevated liver enzymes

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CelecoxibCelebrexNursingConsiderations   Generic Name Celecoxib

Trade Name Celebrex

Indication Osteoarthritis, rheumatoid arthritis, acute pain

Action Decreases pain and inflammation by inhibiting synthesis of prostaglandins

Therapeutic Class Antirheumatics/NSAID

Pharmacologic Class Cox 2 inhibitor

Nursing Considerations • Use caution with cardiovascular disease
• Increases risk for MI, CVA, thrombosis
• May cause GI bleeding, Stevens-Johnson syndrome, dermatitis
• Notify provider for new-onset abdominal pain or black stool

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CefdinirOmnicefNursingConsiderations   Generic Name Cefdinir

Trade Name Omnicef

Indication Treatment of skin infections, otitis media

Action Bactericidal, binds to bacterial cell wall causing cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 3rd generations

Nursing Considerations • Contraindicated in cephalosporin and possibly penicillin allergies
• May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at
IV site, anaphylaxis
• Assess infection and allergies
• Obtain cultures prior to therapy
• Monitor bowel function
• Monitor for bleeding
• May lead to superinfection

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CefaclorCeclorNursingConsiderations   Generic Name Cefaclor Trade Name Ceclor

Indication Treatment of respiratory tract infections, skin infections, otitis media

Action Bactericidal, binds to bacterial cell wall causing cell death

Therapeutic Class Anti-infectives

Pharmacologic Class Cephalosporin 2nd generations

Nursing Considerations • Contraindicated in cephalosporin and possibly penicillin allergies
• May need lead to seizures, pseudomembranous colitis, diarrhea, phlebitis at
IV site, anaphylaxis
• Assess infection and allergies
• Obtain cultures prior to therapy
• Monitor bowel function
• May lead to superinfection

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CalciumCarbonateTumsNursingConsiderations   Generic Name Calcium carbonate

Trade Name Tums/Rolaids

Indication Treatment of hypocalcemia, prevention of postmenopausal osteoporosis, treat-
ment of hyperkalemia and hypermagnesemia, used as antacid

Action Calcium is essential for nervous, muscular, and skeletal systems, helps maintain
cell membranes, aids in transmission of nerve impulses and muscle contraction,
aids in blood formation and coagulation

Therapeutic Class Mineral and electrolyte replacements/supplements

Pharmacologic Class Antacids

Nursing Considerations • May cause cardiac arrest and arrhythmias
• Monitor hemodynamics
• May causes hypotension, bradycardia, and arrhythmias
• Hypercalcemia can increase risk for digoxin toxicity
• Instruct pt on foods that contain Vitamin D and encourage adequate intake
• Monitor parathyroid hormone

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CaptoprilCapotenNursingConsiderations   Generic Name Captopril

Trade Name Capoten

Indication Hypertension, management of CHF, decrease progression of DM neuropathy

Action Block conversion of angiotensin I to angiotensin II, increases renin levels and
decreases aldosterone leading to vasodilation

Therapeutic Class Antihypertensives

Pharmacologic Class ACE Inhibitor

Nursing Considerations • Can cause neutropenia – check WBCs regularly
• Use cautiously with potassium supplements and potassium sparing diuretics
• Use cautiously with diuretic therapy
• Administer 1 hour before meals
• Monitor blood pressure often
• Monitor weight and fluid status
• Monitor renal profile
• Monitor CBC frequently
• May lead to Rhabdomyolysis
• Dry cough

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/ButorphanolStadolNursingConsiderations   Generic Name butorphanol Trade Name Stadol

Indication moderate to severe pain, labor pain, sedation

Action alters perception and response to pain by binding to opiate receptors in CNS

Therapeutic Class Opioid Analgesic

Pharmacologic Class opioid agonists/antagonists

Nursing Considerations • use caution with concurrent use of MAOIs
• may cause confusion, hallucinations, sedation
• monitor for CNS depression
• assess blood pressure pulse and respirations during administration
• administer slowly through an IV line

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BuspironeBusparNursingConsiderations   Generic Name Buspirone

Trade Name Buspar

Indication Management of anxiety

Action Relieves anxiety by binding to dopamine and serotonin receptors

Therapeutic Class Antianxiety

Pharmacologic Class Azapirone

Nursing Considerations • Do not administer concurrently with MAOI or grapefruit juice
• May lead to dizziness, drowsiness, fatigue, and weakness
• Patient may experience chest pain, palpitations, tachycardia
• Instruct patient to take as directed
• Instruct patient to avoid alcohol and other CNS depressantss

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BupropionWellbutrinNursingConsiderations   Name Bupropion

Trade Name Wellbutrin

Indication Depression, smoking cessation, treat ADHD in adults

Action Not well understood, ↑ dopaminergic and noradrenergic transmission via reuptake

Therapeutic Class Antidepressants, smoking deterrents

Pharmacologic Class Aminoketones

Nursing Considerations • May lead to seizures, suicidal thoughts
• Do not administer if patient is taking MAOI
• Use caution with renal and liver impairment
• Assess mental status
• Instruct patient to avoid alcohol (may lead to hallucinations, seizures,
anxiety)

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BismuthSubsalicylatePepto-BismolNursingConsiderations   Generic Name Bismuth subsalicylate

Trade Name Kaopectate, Pepto-Bismol

Indication Diarrhea, heartburn, indigestion, H. pylori associated ulcer

Action Stimulates the absorption of fluids and electrolytes in the intestinal wall, reduction in hypermotility of the stomach, and binds to toxins.

Therapeutic Class Antidiarrheal, antiulcer, antacid

Pharmacologic Class Absorbent

Nursing Considerations • Contraindicated in aspirin hypersensitivity
• Increase risk for impaction with geriatric and pediatric patients
• Monitor liver profile
• Bismuth may interfere with radiologic exams

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BisacodylDulcolaxNursingConsiderations   Generic Name Bisacodyl

Trade Name Dulcolax

Indication Treatment of constipation, bowel regimen

Action Stimulates enteric nerves to cause peristalsis which leads to fluid accumulation in the colon

Therapeutic Class Laxatives

Pharmacologic Class Stimulant laxatives

Nursing Considerations • May lead to hypokalemia
• May cause abdominal pain and cramps
• Not for use within 1 hour of taking milk product
• Assess for abdominal distention and bowel function
• Instruct patient to drink 1500-2000 mL/day during therapy
• Monitor fluid and electrolyte levels
• Instruct patient to take as ordered

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BenztropineCogentinNursingConsiderations   Generic Name Benztropine

Trade Name Cogentin

Indication Treatment for Parkinson’s disease

Action Exhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors

Therapeutic Class Antiparkinson agent

Pharmacologic Class Anticholinergic

Nursing Considerations • May lead to arrhythmias, hypotension, palpitations, and tachycardia
• Anticholinergic effects like constipation, dry mouth
• Assess for extrapyramidal symptoms
• Instruct patient to take as directed
• Instruct patient to maintain good oral hygiene

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AzithromycinZithromaxNursingConsiderations   Generic Name Azithromycin Trade Name Zithromax

Indication URI, chronic bronchitis, lower respiratory infections, otitis media, skin infections, various STIs, prevention of bacterial endocarditis, treatment of cystic fibrosis

Action Inhibits bacterial protein synthesis

Therapeutic Class Agents for atypical mycobacterium, anti-infectives

Pharmacologic Class Macrolide

Nursing Considerations • May lead to pseudomembranous colitis, pain, diarrhea, nausea,
Stevens-Johnson syndrome, angioedema
• May increase risks for warfarin toxicity
• Monitor patient for signs of anaphylaxis
• Instruct patient to notify physician for diarrhea, or blood or pus in stool
• Instruct patient to take medication exactly as prescribed

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/Diphenoxylate-AtropineLomotilNursingConsiderations   Generic Name Diphenoxylate/atropine Trade Name Lomotil

Indication Treatment for diarrhea

Action Inhibits GI motility via anticholinergic effects

Therapeutic Class Antidiarrheal

Pharmacologic Class Anticholinergic

Nursing Considerations • Contraindicated with angle-closure glaucoma, dehydration
• Structurally related to opioids so use caution with patients that have allergies to opioids
• May cause constipation, tachycardia, dizziness, ileus
• Monitor liver function as the medication is excreted by the liver
• Ensure that client is taking medication as prescribed and not double dosing

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AtorvastatinLipitorNursingConsiderations   Generic Name Atropine

Trade Name Atropen

Indication Decreases oral and respiratory secretions, treats sinus bradycardia and heart block, treatment of bronchospasm

Action Atropine is an anticholinergic which means that it inhibits the effects of the parasympathetic nervous system, specifically acetylcholine. This inhibition causes increase in HR, bronchodilation, decreased GI and respiratory secretions.

Therapeutic Class Antiarrhythmic

Pharmacologic Class Anticholinergic, antimuscarinic

Nursing Considerations • Avoid in acute hemorrhage, tachycardia, and angle closure glaucoma
• Monitor patient for tachycardia and palpitations
• May cause urinary retention in elderly patients
• Patients may experience constipation due to slowed GI motility

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AtenololTenorminNursingConsiderations  

Generic Name Atenolol

Trade Name Tenormin

Indication Hypertension, angina, prevention of MI

Action Blocks the stimulation of beta1 receptors in the SNS with minimal effect on beta2 receptors

Therapeutic Class Antianginal, antihypertensive

Pharmacologic Class Beta blocker

Nursing Considerations • Contraindicated in CHF, pulmonary edema, cardiogenic shock, bradycardia,
heart block
• Monitor hemodynamic parameters (HR, BP)
• May cause bradycardia, CHF, pulmonary edema
• Masks symptoms associated with diabetes mellitus
• Advise to change positions slowly to prevent orthostatic hypotension
• Instruct patient on how to take blood pressure

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/ASAAspirinNursingConsiderations   Generic Name Acetylsalicylic Acid

Trade Name Aspirin

Indication Rheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis

Action Inhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases

Therapeutic Class Antipyretics, non-opioid analgesics

Pharmacologic Class Salicylates

Nursing Considerations • Use caution in bleeding disorders, chronic alcohol use
• May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis
• Increases risk for bleeding with warfarin, heparin, and clopidogrel
• Increased risk for GI bleeding with NSAID use
• Monitor liver function tests
• Concurrent use with alcohol may increase risk for GI bleeding
• Aspirin with viral infections can cause Reye’s syndrome

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AmpicillinOmnipenNursingConsiderations   Generic Name Ampicillin

Trade Name Principen

Indication Skin infections, soft tissue infections, otitis media, sinusitis, respiratory infections, GU infections, meningitis, septicemia

Action Bactericidal, broader spectrum than penicillin, binds to cell wall leading to bacterial cell death

Therapeutic Class Anti-infective

Pharmacologic Class Aminopenicillin

Nursing Considerations • Contraindicated in penicillin allergy, use caution in renal insufficiency
• May lead to seizures, diarrhea, anaphylaxis, superinfection
• Assess for infection
• Monitor liver function tests
• Instruct patient on signs of superinfection: furry overgrowth on tongue,
vaginal itching, loose and foul smelling stool
• Pt should not use with oral contraceptive use.

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AmoxicillinAmoxilNursingConsiderations   Generic Name amoxicillin

Trade Name Moxatag

Indication skin infections, respiratory infections, sinusitis, endocarditis prophylaxis, lyme disease

Action Inhibits synthesis of bacterial cell wall leading to cell death.

Therapeutic Class anti-infectives, antiulcer agent

Pharmacologic Class aminopenicillins

Nursing Considerations • contraindicated with penicillin allergy
• may cause seizures
• assess for rash, anaphylaxis
• excreted by kidneys – monitor renal labs
• monitor patient for diarrhea – bloody stool should be reported immediately

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AmlodipineNorvascNursingConsiderations   Generic Name Amlodipine

Trade Name Norvasc

Indication Hypertension, angina

Action Blocks transport of calcium into muscle cells inhibiting excitation and contraction

Therapeutic Class Antihypertensive

Pharmacologic Class Ca channel blocker

Nursing Considerations • May cause gingival hyperplasia
• Grapefruit juice may increase drug level
• Monitor blood pressure and pulse prior to and during therapy
• Monitor intake and output
• Assess for signs of CHF
• Assess characteristics of angina
• Instruct patient of interventions for hypertension and how to take blood
pressure

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AmiodaronePaceroneNursingConsiderations   Generic Name Amiodarone

Trade Name Cordarone

Indication a-fib, ventricular arrhythmias, SVT, ACLS protocol for v-fib and v-tach

Action Prolongs phase 3 of the action potential, makes the heart more tolerant to arrhythmias, inhibits adrenergic stimulation, slows rate, decreases peripheral vascular resistance causing vasodilation

Therapeutic Class Antiarrhythmic class III, potassium channel blocker

Pharmacologic Class None

Nursing Considerations • May lead to ARDS, pulmonary toxicity, CHF, bradycardia, hypotension
• Increases risk for QT prolongation
• Increases digoxin levels
• Increases activity of warfarin
• Monitor EKG continuously while on therapy
• Assess for signs and symptoms of ARDS
• Monitor liver function test
• Check dosage with another RN
• Teach pt to monitor pulse daily and report abnormalities
• Avoid drinking grapefruit juice

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AlprazolamXanaxNursingConsiderations   Generic Name Alprazolam

Trade Name Xanax

Indication Anxiety, panic disorder, manage symptoms of PMS, insomnia, mania, psychosis

Action Works in CNS to produce anxiolytic effect causing CNS depression.

Therapeutic Class Antianxiety agent

Pharmacologic Class Benzodiazepine

Nursing Considerations • Use caution with existing CNS depression, sleep apnea, renal dysfunction,
hepatic dysfunction.
• May cause CNS depression, drowsiness, lethargy
• May lead to physical dependence, may experience tolerance effect
• Assess anxiety and mental status
• Romazicon (flumazenil) is the antidote for overdose
• Grapefruit juice may increase blood levels

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AlendronatefosamaxNursingConsiderations Generic Name Alendronate

Trade Name Fosamax

Indication Osteoporosis (aging, menopause, corticosteroid induced)

Action Inhibits osteoclast activity leading to inhibition of resorption of bone

Therapeutic Class Bone resorption inhibitor

Pharmacologic Class Bisphosphonates

Nursing Considerations • Take first thing in the morning with full glass of water 30 min prior to eating
• Assess serum calcium and vitamin D
• May lead to muscle pain

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/AlbuterolVentolinNursingConsiderations Generic Name Albuterol

Trade Name Proventil

Indication Bronchodilator used to prevent airway obstruction in asthma and COPD

Action Binds to Beta2 adrenergic receptors in the airway leading to relaxation of the smooth muscles in the airways

Therapeutic Class Bronchodilator

Pharmacologic Class Adrenergic

Nursing Considerations • May decrease the effectiveness of Beta Blockers
• Use caution with
○ Heart disease
○ Diabetes
○ Glaucoma
○ Seizure disorder
• Overuse of inhalers can lead to bronchospasm
• Monitor for chest pain and palpitations
• Can decrease digoxin levels

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/Insulin–ShortActingRegularNursingConsiderations Generic Name Insulin Regular

Trade Name Humulin R/Novolin R

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Subcutaneous | 30-45 min | 1-5 | 4.5-6h |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/Insulin–IntermediateActingNPHNursingConsiderations Generic Name Insulin NPH

Trade Name Humulin N, Novolin N

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Subcutaneous | 1-2 hr | 4-12hr | 18-24hr |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/Insulin–LongActingLantusNursingConsiderations Generic Name Insulin detemir, Insulin glargine

Trade Name Levemir, Lantus

Indication hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver,
prevents breakdown of fat and protein

| Route | Onset | Peak | Duration | | Detemir | 3-4 hr | 3-14 hr | 24 hr | | Glargine | 3-4 hr | none | 24 hr |

Therapeutic Class antidiabetics, hormones

Pharmacologic Class pancreatics

Nursing Considerations • assess for symptoms of hypoglycemia or hyperglycemia
• monitor body weight over time
• may cause decreased inorganic phosphates, potassium, and magnesium
• monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/CalciumAcetatePhosLoNursingConsiderations

Generic Name calcium acetate

Trade Name PhosLo

Indication treatment of hypocalcemia, prevention of post-menopausal osteoporosis, treatment of hyperkalemia and hypermagnesaemia, adjunct in cardiac arrest, control of hyperphosphatemia with ESRD. Binds to phosphate in food and prevents absorption.

Action calcium is essential for nervous muscular and skeletal systems, helps maintain cell membranes, aids in transmission of nerve impulses and muscle contraction, aids in blood formation and coagulation

Therapeutic Class mineral and electrolyte replacements/supplements

Pharmacologic Class antacids

Nursing Considerations • may cause cardiac arrest and arrhythmias
• phlebitis at site of insertion
• monitor hemodynamics
• may cause hypotension, bradycardia, and arrhythmias
• hypercalcemia can increase risk for digoxin toxicity
• administer slowly
• instruct pt on foods that contain Vitamin D and encourage adequate intake.
• monitor parathyroid hormone

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     **Download the cheat: https://bit.ly/50-meds**  **View the lesson: https://bit.ly/AcyclovirZoviraxNursingConsiderations**

What is the Generic Name Acyclovir

             **What is the Trade Name for Acyclovir**      Zovirax

             **What is the Indication for Acyclovir**      Genital herpes, herpes zoster, chicken pox

             **What is the Action of Acyclovir**      Interferes with viral DNA synthesis

             **What is the Therapeutic Class of Acyclovir**      Antiviral

             **What is the Pharmacologic Class of Acyclovir**      Purine analogues

             **What are the Nursing Considerations for Acyclovir**      * May cause seizures, renal failure, Stevens-Johnson syndrome, thrombotic thrombocytopenic purpura syndrome, diarrhea, dizziness, nausea
  • Monitor renal panel during administration
  • Assess lesions
  • Instruct patient to use proper protection during sexual intercourse

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50 Meds Download: https://bit.ly/50-meds What is the Generic Name Acetaminophen

What is the Trade Name for Acetaminophen Tylenol

What is the Indication for Acetaminophen Pain, fever

What is the Action of Acetaminophen Inhibit the synthesis of prostaglandins which play a role in transmission of pain signals and fever response

What is the Therapeutic Class of Acetaminophen Antipyretic, non-opioid analgesic

What are the Nursing Considerations for Acetaminophen • Do not exceed 4g of acetaminophen per day to limit risk for liver, renal,
and cardiac damage
• Overdose will lead to hepatotoxicity
• Acetadote is the antidote for overdose
• May increase risk for bleed with warfarin therapy
• May alter blood glucose measurements