IC Healer Podcast: Recent Episodes
Mandy
This show is about how you can harness the power of your immune system to put your bladder pain to remission as I have done for myself and many of my patients. Nutrition is the single most important lever we have influencing our health and wellbeing for better or for worse. Each episode will discuss various tools we can use to optimize this lever, whether it is diet, nutrigenomics, environment, supplements or even mindset.
In this episode, we dive into the latest research from the Cleveland Clinic on the connection between the gut microbiome and oxalates.
Key topics include:
- How diets rich in fats and sugars can impair your ability to process oxalates.
- The role of bile acids in oxalate metabolism and how an imbalanced microbiome disrupts this process.
- The link between gut dysbiosis, endotoxemia, and chronic inflammation.
- How poor gut health can lead to chronic UTIs and other long-term health issues.
These are explained in more detail in this blog --> https://ichealer.com/the-influence-of-oxalate-on-gut-microbiota-a-two-way-street/
I'll be breaking down these insights and explaining why maintaining a healthy gut microbiome is crucial for managing oxalates and overall health.
Connect with Dr. Mandy
Watch episodes on YouTubeGo deeper with Dr. Mandy in the IC Healer Self Healing CourseFollow Dr. Mandy on InstagramDr. Mandy's Tik TokSign up for Dr. Mandy's NewsletterOther Podcast interview with Dr. MandyThe Issue with Oxalates on Ditch the Quick FixFunctional medicine with Dr. MandyDr. Haley interview on Interstitial CystitisOpen your Eyes Podcast- Everyday NutritionOpen your Eyes Podcast - Why we get sickLive UTI Free- Immune System and UTIIC WellnessDr. Adam Rind
In this episode of "Thyroid Talk," we explore the fascinating and often overlooked connections between thyroid function, histamine intolerance, and overall health. We dive deep into the role of mast cells, histamine, and how thyroid dysfunction might contribute to chronic symptoms like bladder pain, interstitial cystitis, and more. Learn how factors like copper toxicity, calcium imbalance, iodine deficiency, and even nutrient deficiencies impact thyroid health and histamine regulation.
Plus, discover actionable steps to help manage these issues, including the right tests, dietary changes, and how supporting gut health can make all the difference. If you’ve been struggling with unexplained symptoms or want to uncover hidden connections affecting your health, this episode is a must-listen. Tune in to gain valuable insights and start taking control of your thyroid and overall well-being today!
Connect with Dr. Mandy
Watch episodes on YouTubeGo deeper with Dr. Mandy in the IC Healer Self Healing CourseFollow Dr. Mandy on InstagramDr. Mandy's Tik TokSign up for Dr. Mandy's NewsletterOther Podcast interview with Dr. MandyThe Issue with Oxalates on Ditch the Quick FixFunctional medicine with Dr. MandyDr. Haley interview on Interstitial CystitisOpen your Eyes Podcast- Everyday NutritionOpen your Eyes Podcast - Why we get sickLive UTI Free- Immune System and UTIIC WellnessDr. Adam Rind
In this episode, we delve into the complex topics of copper toxicity and histamine. We explore histamine intolerance, its role in the body, and its impact on the gut and bladder. Copper plays a crucial role in histamine degradation, and we discuss how imbalances in copper can lead to histamine intolerance and affect everyday life.
We cover a range of important topics, including:
- The symptoms of histamine intolerance and how they impact daily living
- Nutrients involved in histamine degradation, such as DAO and other enzymes
- The difference between copper toxicity and copper deficiency
- Symptoms of copper toxicity and the factors that contribute to it, including diet and oral contraceptives
- Practical steps you can take to address and fix copper toxicity
For those struggling with histamine intolerance and related issues, this episode offers valuable insights and actionable advice.
Connect with Dr. Mandy
Watch episodes on YouTubeGo deeper with Dr. Mandy in the IC Healer Self Healing CourseFollow Dr. Mandy on InstagramDr. Mandy's Tik TokSign up for Dr. Mandy's Newsletter
In this Podcast, Scott Compton and I have a great conversation about fasting. Fasting has really transformed my health, helped me lose a lot of bodyfat, reduce inflammation, improve my bladder issues and also has helped me achieve successful pregnancy over age 40. It is truly a great method for anti-aging and longevity.
Join us as we discover the powers of the fasting and how it can optimize your health and increase your life span!
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.com/rootcause/
People with bladder pain syndrome can present with a complex array of symptoms which often can stem from MOLD TOXICITY. This can present as a multitude of symptoms, such as bloating, digestive disturbances, brain fog, depression, and inflammation. Mold can produce loads of inflammation and oxidative stress which can in turn ramp up your body's oxalate production.
Mold testing is controversial. Urine testing is convenient, but can often be false negative particularly if patients have poor detox pathways. The best test is mold antibody testing, as this gives you insight on what the mycotoxins are doing to your IMMUNE system. Often times, patients with low urinary oxalates present with very high IgE antibodies, which indicates mast cell activation.
Learn more about the MyMycolab test and other mold related topics in this interview with Dr. Andrew Campbell, MD, medical director of Mymyolabs.
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For those of you who are suffering in pain, you don't want to miss this interview.⠀⠀
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.ac-page.com/root-cause-e-book
Poor Gut health is rampant! In this interview with Dr. Haroldo, we talk about all topics gut health. Your diet, your lifestyle all play a role. We debunk some common diet fads and how they can affect the microbiome.
⠀⠀⠀
For those of you who are suffering in pain, you don't want to miss this interview.⠀⠀
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.ac-page.com/root-cause-e-book
In this Podcast, I am interviewing the founder of Vykon- Lisa Pitel- Killah! Everyone knows how much I LOVE my Vykon. It has totally been a game changer in personalized nutrition and has really simplified supplementation for myself, my family and my patients.
Join us as we discover the powers of the HTMA, and the plethora of clues this simple test can give you about your health and physiology. We also dive into VYKON and why this duo is such a great additional to your healing and healthy optimizing strategy.
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.ac-page.com/root-cause-e-book
People with bladder pain syndrome can present with a complex array of symptoms which stem from an underlying gut dysfunction. This can present as a multitude of symptoms, such as bloating, digestive disturbances, brain fog, depression, and inflammation. However, bladder dysfunction is often a feature of this problem. In this interview, we will examine why you need to heal your gut to heal your bladder.
⠀⠀⠀
For those of you who are suffering in pain, you don't want to miss this interview.⠀⠀
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.ac-page.com/root-cause-e-book
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❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.com/rootcause/
People who are low in thiamine can present with a complex array of symptoms which stem from underlying autonomic nervous system dysfunction. The primary complaints may center around central/peripheral neurological issues, cardiovascular abnormalities, gastrointestinal distress, or a mixture of all three. However, bladder dysfunction is often a feature of this problem. In this interview, we will examine how thiamine deficiency can manifest as underactive or overactive bladder function
⠀⠀⠀
For those of you who are suffering in pain, you don't want to miss this interview.⠀⠀
❤️ I am Dr. Mandy LaGreca, I am the #1 expert in IC Healing and helping you find your Root cause. I am a licensed Doctor in Clinical Nutrition (DCN). I am also a Certified Nutrition Specialist (CNS) and a Functional Diagnostic Nutrition Practitioner (FDN-P) where we use the scientific lab testing to identify your root cause to help you identify healing opportunities.
❤️🙌As many of you know, I have worked really hard to figure out the root causes of IC and Bladder Pain Syndrome. IC is what I call a perfect storm: there is not one root cause, but a complex interaction of many of them.
👉 And each person has their own story and blueprint as to what may have triggered it. The single most important thing you can do to start your remission journey is to identify your ROOT cause. That is what we do best here at IC Healer!
😍 You can learn more about the Root Cause Investigation https://ichealer.ac-page.com/root-cause-e-book
Dr. Cheryl Burdette, ND, Founder & Education Director of Precision Point Diagnostics, walks us through this talk that focuses on the research around food sensitivities and allergies and why it is a viable and critical part of the management of inflammatory and oxidative pathologies.
SummaryThe immune system has many ways it reacts to foods. As we look at these immune complexes together, we can get a more accurate picture that helps us determine what dietary intervention has the most significant therapeutic value for that patient and condition.
Precision Point’s P88 Dietary Antigen Test gives practitioners an overview of 4 different types of immune-mediated responses. By removing these trigger foods, the patient will have the opportunity to reduce overall inflammation within the body.
Why Test for Food Sensitivities (IgG) and Allergies (IgE)?
Testing IgG and IgE can give us practitioners a clearer picture of what is happening within the body. Once we know what the patient is reacting to, we will have the information to guide them through nutritional therapy, decreasing the body’s immune response.
Symptoms Associated with Food Reactions
• Auto-Immune Conditions
• Histamine or mast cell activation syndrome
• Painful bladder or Interstitial cystitis
• Constipation or Diarrhea
• Decreased immune function
• Weight Gain
• Depression/Anxiety
• Fatigue/Poor Sleep
• Gas or bloating
• Gastroesophageal reflux
• Headache or migraine
• Hives, rash, eczema, or edema
• Joint pain and inflammation
• Poor absorption of valuable vitamins and minerals
Precision Point P88 Dietary Antigen Test
The P88 Test is unique because it not only tests for food sensitivities but also food allergies. This Test detects IgE, multiple classes of IgG, and complement, which results in a higher sensitivity.
Unique Features of P88 Antigen Test
• Measures 4 immune reactions with an add on of a fifth (sIgA) if desired
• Shows which allergies have developed a tolerance to (most testing only show allergic reaction but not when you have adapted to the antigen)
• Provides an Immune Index, listing all foods from highest to lowest, so you know which foods to avoid in a simple format.
• Provides multiple diet choices for the patient so you can match their needs from more symptomatic to less symptomatic
Today I am going to be interviewing Dr. Peter Osbourne. Dr. Osbourne is a worldwide functional medicine doctor often called the Gluten Free warrior., is the author of the international best selling book, No Grain No Pain
Dr. Peter Osborne is a doctor of chiropractic, doctor of pastoral science, an expert in functional nutrition, and is Board Certified with The American Clinical Board of Nutrition.
Often times referred to as “The Gluten Free Warrior”, He is one of the world’s leading authorities on gluten sensitivity, and lectures nationally to both the public as well as doctors on this and many other nutritionally related topics.
He is the founder Gluten Free Society, the author of The Gluten Free Health Solution and The Glutenology Health Matrix, a series of digital videos and ebooks designed to help educate the world about gluten. In addition, he is the author of the international best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster), which was also printed in 5 languages and turned into a PBS special that aired nationwide.
Dr. Osborne has served as the executive director and the vice president for the American Clinical Board of Nutrition. He was an adjunct professor at HCC and Texas Women’s University teaching nutrition and neurophysiology to nursing and occupational therapy students. He currently serves on the advisory board for Functional Medicine University.
My eyes opened to the role of wheat and grains in the inflammatory cascade in many autoimmune conditions such as IC and BPS with my own journey when I learned about my leaky gut and gluten intolerance.
I personally have had to embark on a grain free diet to heal, and have to often educate my own patients about the role their diet is playing into their condition. Stay tuned, this is a great interview with a great learning opportunity.
Oxalates are killing you slowly, and you probably do not even realize it. If you have unexplained symptoms that your doctors have no idea what is causing it, consider oxalates as a possible reason for your pain and inflammation.
In this 3-way interview, I talk to the Low Ox Coach and Low Ox Grandma to discuss this and some other very important topics.
This is an open ended conversation in which the three of us share our experience and stories, and how we used the low oxalate diet to heal our chronic health conditions.
Follow them on Instagram:
drmandydcn
lowoxcoach
lowoxgrandma
Today I am going to be interviewing a very special person. I am interviewing Sally K. Norton.
Sally is renowned nutritionist and expert in the role of toxic superfoods such as oxalates.
Sally K. Norton realized when she was 12 that she wanted to help people improve their health by eating a better diet.
She earned a Bachelor's degree in Nutritional Science from Cornell University, and a Master’s in Public Health from the University of North Carolina.
Sally ate vegetarian and vegan for years, yet her health deteriorated, and she was finally unable to continue in her public health research career.
Standard and alternative medicine proved no match for her wide range of health issues, which included severe joint pain, digestive problems, and autoimmune issues as well as sleep and neurological problems.
She got serious about low-oxalate eating after reading that it might help her joint problems. Unexpectedly, EVERYTHING got better.
Sally started studying oxalates in earnest to understand how such a thing could be possible, talking with people about their own health issues, and discovering how widespread and devastating dietary oxalate poisoning is.
Sally has helped hundreds of people in her consulting practice improve their health by adopting a low-oxalate diet. Her forthcoming book, Toxic Superfoods (Rodale Books / Penguin-Random House, December 2022), explores the remarkable history and science of oxalates, how we can wreck our health by trying to eat healthily, and how we can get better by lowering our oxalate intake.
Sally is going to share with us today some of what she has learned about oxalates, and how lowering oxalate intake can benefit your health.
Over the past few years I have come to really appreciate the role oxalates play in many chronic health conditions such as bladder pain syndrome and interstitial cystitis
For those who new here, interstitial cystitis is a painful bladder condition characterized by many symptoms such as urgency, frequency, painful urination, pelvic pain and even vulvodynia.
👉 Recent findings have strongly associated this condition with oxalates, mast cells and histamines, and I have actually seen this myself in clinical practice with various tests we can run to identify these triggers.
Video highlights:
High oxalate diet 00:08:00
Sally's health 00:10:00
Oxalate misconception 00:15:46
Lab testing misconceptions 00:18.20
Why oxalates are bad for everyone 00:20:46
Thyroid and oxalates 00:27:00
Chronic pain that oxalates cause 00:29:00
How oxalates impair liver detox 00:30:00
Why its important to be chronic pain free 00:32:00
How oxalates affect salivary glands 00:33:20
How 1 spinach smoothie can damage your body 00:36:30
How oxalates trigger autoimmunity 00:38:00
Where does oxalate concentrate? 00:39:00
How oxalate irritates the bladder 00:40:00
How long does dumping take? 00:42:57
Which people do really well with the LOD? 00:45:07
Why there is variability in healing 00:45:23
Itchy skin and oxalates 00:46:35
DEXA scan for oxalate 00:48:00
Common dumping symptoms 00:49: 35
Low ox diet is not restrictive 00:51:00
Today I am going to be interviewing a very good friend and colleague of mine who is also a doctor in clinical nutrition like myself, as well as a CNS.
I am interviewing Dr. Gail Clayton.
Dr. Clayton renowned clinical nutritionist and expert in nutritional biochemistry and also mold toxicity.
Dr. Clayton, like many of us has had her own health struggles with mold.
This is what motivated her to dive deeper than the medical community could offer her, and to pursue a career in clinical and functional nutrition
I am honored to have this opportunity to speak with her today, so stay tuned, this is an interview you do NOT want to miss.
Some key concepts:
0:5:00 What is histamine?
0:7:26 What are symptoms of excessive histamine?
0:13:00 Metabolism of histamine
0:18:40 Histamine food assessment
0:26:00 OTC Antihistamines
0:29:00 Mast cell stabilizer- script
0:36:00 Polyphenols
0:38:00 Phenol sensitivity
0:40:00 Approach to extreme sensitivity
0:53:00 Loss of tolerance
0:56:00 Preloaded Mast cells
0:58:00 Sleep
1:00:00 Mast cells activate the amygdala
1:01:00- Fight or flight and histamine
1:06:00- Limbic retraining
1:08:00 Stress reduction
In this episode, I am interviewing Bob Miller, the founder of the Tree of Life Functional Genomic Analysis. I am here with Bob Miller today to dive into some very important concepts when it comes to bladder pain and IC, which includes histamine and oxalates and how they relate to inflammation and detox pathways. Bob Miller has been doing some amazing work with his company Nutrigenetic research and dives into pathways and genomics of mechanisms that we see in clinical practice.
Recent findings have strongly associated IC/BPS condition with oxalates, mast cells and histamines, and I have actually seen this myself in clinical practice with various tests we can run to identify these triggers. Also, I am finding mold seems to be a big problem with this population too.
The audio version of this can be quite educational and informative. To view the full video, visit my Youtube interview at IC Healer's Youtube Channel and be sure to subscribe to be alerted for future interviews.
Some key concepts:
- What are genetic polymorphisms?
- How are mast cells associated with IC?
- Histamines?
- Oxalates and histamines?
- How do oxalates promote inflammation?
- What pathways are associated with inflammation and histamines of IC pain?
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