eHIV Review: Recent Episodes
eHIV Review
Expert insight and analysis providing information directly relevant to HIV care, through topic-focused newsletters summarizing the peer-reviewed literature and accompanying podcasts to illustrate how to apply that information in the clinic.
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Current ART regimens can successfully manage HIV infection in nearly all PLWH. But what happens when a patient with HIV is coinfected with a dangerous pathogen ART alone cannot handle? Two of the most common are hepatitis B and latent tuberculosis infection.
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Pregnancy and menopause — for many women, these are two of the most significant healthcare events in their lives. For WLWH (women living with HIV) and their healthcare providers, managing these life-changing periods is often complicated by many questions.
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In part 1 of this eHIV Review Special Edition (still available at eHIVreview.org), eHIV Review Program Director Justin Alves, Nurse Educator at Boston Medical Center, reviewed the recent evidence describing some of the barriers to care experienced by marginalized individuals at risk for or living with HIV. In this Part 2 issue, he again calls upon two front-line clinicians in the fight to end the HIV epidemic in the U.S. — Nicky Mehtani, MD, from UCSF Medical Center in San Francisco, and Vanessa Loukas, NP, from Boston University’s Chobanian & Avedisian School of Medicine —to share their clinical approaches.
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Marginalized individuals at risk for or living with HIV — the formerly incarcerated, immigrants, people with unstable housing, residents of rural communities, the rising number with substance use disorder — have long faced disparities in obtaining adequate health care. What do HCPs need to know to understand the unique needs of these underserved populations? How can they provide meaningful, helpful, and culturally sensitive care? What barriers continue to prevent their being brought into the HIV care continuum?
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Marginalized individuals at risk for or living with HIV — the formerly incarcerated, immigrants, people with unstable housing, residents of rural communities, the rising number with substance use disorder — have long faced disparities in obtaining adequate health care. What do HCPs need to know to understand the unique needs of these underserved populations? How can they provide meaningful, helpful, and culturally sensitive care? What barriers continue to prevent their being brought into the HIV care continuum?
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A wealth of evidence confirms that adolescents and young adults (AYA) are indeed a priority population whose needs must be addressed for the US Ending the HIV Epidemic program to be successful. What do providers need to know about AYA to bring more of these patients into the HIV care continuum? What should they be doing? And what should they avoid doing?
Join us as guest author Dr. Vincent Guilamo-Ramos from the Duke University School of Nursing answers these and other questions, in this issue of eHIV Review.
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Companion newsletter: https://elit.dkbmed.com/issues/182
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A wealth of evidence confirms that adolescents and young adults (AYA) are indeed a priority population whose needs must be addressed for the US Ending the HIV Epidemic program to be successful. What do providers need to know about AYA to bring more of these patients into the HIV care continuum? What should they be doing? And what should they avoid doing?
Join us as guest author Dr. Vincent Guilamo-Ramos from the Duke University School of Nursing answers these and other questions, in this issue of eHIV Review.
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Companion newsletter: https://elit.dkbmed.com/issues/175
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Why do cisgender and transgender women, and particularly women of color, account for such a disproportionate percentage of HIV infections in the US? Why are so many so reluctant to accept PrEP? What can clinicians do to bridge this critical gap in essential HIV services?
These are some of the questions Guest Author Dr. Kathleen McManus, from the Division of Infectious Diseases and International Health at the University of Virginia, discusses in this issue of eHIV Review.
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Non-nucleoside reverse transcriptase inhibitors (NNRTIs). Rilpivirine, in combination with cabotegravir, provides a long-acting injectable option for both treatment and PrEP. But what risk factors have been associated with virologic failure? Doravirine appears to provide a favorable impact on weight and lipid outcomes, but with a lower genetic barrier to resistance. Which patients is it right for and in which ones should it be avoided?
Join us as we discuss Newer NNRTI Agents in Clinical Practice with Dr. Darcy Wooten from the Division of Infectious Disease at the University of California, San Diego, in this issue of eHIV Review.
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Stigma. What is it, and where does it come from? How do LGBTQ+ individuals, particularly those with HIV, experience it? How does stigma affect their mental health? What effect does it have on their engagement in HIV care? What do health care providers need to change to minimize stigma in their practices?
These are some of the questions advanced practice nurse Dallas Ducar, CEO of Transhealth, discusses in this issue of eHIV Review.
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Treatment-experienced patients with RAMs — resistance-associated mutations — remain a difficult management challenge. Every case of HIV drug resistance requires a therapeutic regimen individualized for each patient’s ART history. How will new and in-development agents affect the equation?
Which drug combinations are right? Where does the balance between side effects and adherence lie?
These are some of the questions Dr. Brian Wood from the Division of Allergy and Infectious Diseases at the University of Washington in Seattle addresses in this eHIV Review podcast.
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Most people living with HIV gain weight when initiating ART. For some, the weight gain signifies a “return to health”; for others, the additional weight can be clinically significant and may be strongly associated with an increased risk of metabolic abnormalities. What causes this weight gain? How can patients most at risk for weight-related comorbidities be identified?
Join us as we discuss these and other issues with Dr. Todd Brown, Professor of Medicine and Epidemiology at Johns Hopkins University, in this eHIV Review podcast.
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Are PLWH at higher risk for increased mortality from COVID-19 infection? How important is it for PWLH to get vaccinated and boosted? Is breakthrough COVID-19 infection more likely to occur among PLWH? What about “long COVID” (PASC)?
Join Clinical Research Nurse Diane Kanjilal, manager of the Infectious Disease Clinical Research Unit at Massachusetts General Hospital, as we discuss these questions in this eHIV Review podcast.
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Long-acting injectable antiretroviral therapy is expected to improve adherence, reduce patient burden, and lower community viral load. But for which patients is it suitable? Can it be used as pre-exposure prophylaxis? How does the promise of long-acting ART actually mean in practice?
Join us for this eHIV Review podcast, as Dr. Tanyaporn Wansom, Senior Infectious Diseases Consultant at Chayun Consulting in Bangkok Thailand, takes us to the clinic to answer some of these key questions
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Twenty percent of new HIV diagnoses occur among adolescents and young adults. They’re a population underserved by HIV prevention resources, with lower retention in HIV care. Their awareness and uptake of PrEP has been and remains low. What can their clinicians do to more effectively help these vulnerable young people?
Join Dr. Luis Rubio from University of California San Francisco as we explore these and other important issues in this eHIV Review podcast.
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Rapid ART — initiating ART as soon as possible after an HIV diagnosis: How effective is it at bringing people with newly diagnosed HIV into lasting care? When and how should it be initiated? Are there particular populations where attempting rapid ART should be avoided?
Join us as we discuss these issues with Dr. Jonathan Colasanti from Atlanta’s Emory University and Grady Health System, in this eHIV Review podcast.
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Undocumented LatinX immigrants are a special population facing many difficulties that hinder their engagement in HIV care and prevention. One obvious barrier is language: many undocumented immigrants do not understand either spoken or written English. Many may have never received routine medical care before and can be baffled by the complexities of the medical system. Insurance status and financial concerns are additional barriers. Finally, HIV-related stigma and fear of disclosure of their HIV and/or immigration status can prevent undocumented Latinx immigrants from engaging in HIV care and prevention.
How can clinicians most effectively help these individuals receive proper care? Join us as we find out, with Dr. Kathleen Page and nurse Owen Smith from Johns Hopkins University, in this eHIV Review podcast.
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Better tolerability. More convenient dosing. Less serious side effects. Fewer potential drug-drug interactions. These are some of the most common reasons why individuals living with HIV want or need to change their currently successful ART regimens.
But what do clinicians need to consider when determining which ART to switch to? What role do the patient’s comorbidities play in the selection process? How do changes in the patient’s condition not related to HIV affect the safety and efficacy of their current regimen? What does the evidence say?
Join us in this eHIV Review podcast for a case-based discussion with Dr. Natasha Chida, from the Division of Infectious Diseases at the Johns Hopkins University School of Medicine, about these increasingly important issues.
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Do antivirals increase weight gain? Does PrEP reduce the effect of gender-affirming hormone therapy in transgender women?
Join us in the clinic with Dr. Sarah Puryear from the University of California San Francisco as we discuss these important questions.
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How can the emergency department become more effective in identifying acute HIV infection? What are the missed opportunities for screening? How can existing protocols be adapted to identify more patients with HIV infection without compromising clinicians’ ability to provide emergent care? Those are some of the questions we’re here to discuss today, with Dr. Douglas White and Dr. Erik Anderson from Highland Hospital’s Department of Emergency Medicine, part of the Alameda Health System in Oakland, California
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Nearly two of three new HIV infections in the United States appear in transgender women and men who have sex with men (MSM), with most transmission coming from people unaware of their infection. What should clinicians do to increase the rate of HIV screening in these populations to meet guideline recommendations?
In this eHIV Review podcast, Dr. Robert Goldstein from Harvard Medical School and Massachusetts General Hospital takes us to the clinic to explain how HIV risk in these special populations can be identified and infection prevented.
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What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
In addition to presenting his analysis of the data-driven evidence describing the effects of the COVID-19 virus on people with living with HIV, Dr. Spinelli also spoke directly with front-line clinicians to learn about what they’ve been experiencing as they work to maintain their patients’ health in this disrupted health care system.
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What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
What do the currently published findings say about the effects of the COVID pandemic on people living with HIV? How is the pandemic affecting patients and clinicians in HIV care delivery and the health of people living with HIV?
That’s the dual focus of this eHIV Review Special Edition issue. Matthew Spinelli, MD, MAS, assistant professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital, analyzes the current literature that addresses these questions, and then speaks directly with front-line clinicians about what they’re experiencing as they navigate a disrupted health care system.
Take our post-test to claim CME credits.
To read a companion newsletter click here.
Why do PWID — people who inject drugs — continue as an uncontrolled source of HIV infection? Where are the missed opportunities for increased screening in this population? What barriers have been identified and what strategies can successfully overcome them? Which harm reduction initiatives have been proved effective, and can they be cost-effectively replicated?
In this eHIV Review podcast, Dr. Josh Barocas from the Boston University School of Medicine and Boston Medical Center, and Dr. Raagini Jawa, an infectious disease and addiction medicine fellow at Boston Medical Center, provide a clinical perspective on these important questions.
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Both the on-going syphilis and HIV epidemics are highly concentrated among men who have sex with men. While PrEP has been proven to reduce HIV transmission, it is not designed to prevent sexually transmitted infections like gonorrhea, syphilis, and chlamydia. What does the evidence say about reducing STI risk in MSM, and how can it be most effectively applied in practice?
In this podcast, Dr. Matthew Spinelli — Assistant Professor in the Division of HIV, ID, and Global Medicine at the University of California, San Francisco and San Francisco General Hospital — takes us to the clinic to explain what providers can do to help their patients avoid acquiring and transmitting STIs.
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Our ability to reduce HIV infection and transmission depends on testing, in particular assessing the status of at-risk people who continue to remain untested.
In this issue, Dr. Cedric Bien-Gund from the Division of Infectious Diseases at the University of Pennsylvania takes us to the clinic to explain the pros and cons of the currently available HIV tests and explains which are best to use in particular clinical circumstances.
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In the US, nearly half of all people living with HIV are now aged 50 years or older. Their health care providers face new challenges in managing the effects of aging in their patients. In this eHIV Review podcast, Dr. Maile Young Karris from the University of California San Diego provides clinical insight into HIV and aging.
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In the US, among women at high risk for acquiring HIV infection, only around 2% have initiated PrEP. What are the patient, provider, and system barriers to increased PrEP uptake in this vulnerable population? What can clinicians do to overcome these barriers?
In this issue, Dr. Rachel Scott, Scientific Director of Women's Health Research at the MedStar Health Research Institute and Assistant Professor of Obstetrics and Gynecology at the Georgetown University School of Medicine, provides some answers.
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People who inject drugs (PWID) are at risk for HIV infection from both sexual- as well as injection-related causes. What can clinicians do to reduce the incidence of infection and improve their patients’ health?
In this issue, Dr. Jessica Taylor from The Boston University School of Medicine and Boston Medical Center takes us into the clinic to explain how current evidence-based strategies can increase the uptake of HIV pre-exposure prophylaxis in this vulnerable population.
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In her recent newsletter issue (eHIV Review V5 #1), Dr. Ethel Weld, Assistant Professor of Medicine, Pharmacology and Molecular Sciences at the Johns Hopkins School of Medicine, analyzed the current research about the potential uses of two-drug ART regimens. Join her now for a case-based discussion about how that new information can affect patient selection in the clinic.
Volume 4, Issue 12
“U=U” — an Undetectable HIV viral load means Untransmittable HIV virus. In her recent eHIV Newsletter Issue (Vol. 4; No. 11), Dr. Jill Blumenthal from the Division of Infectious Diseases and Global Public Health at the University of California San Diego analyzed the current evidence strongly supporting this concept. In this Podcast, she discusses “U=U” from the clinical perspective, and models how it can help promote patient safety.
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Volume 4, Issue 10
In this Issue, Dr. Joyce Jones from the Johns Hopkins University School of Medicine and Dr. Barbara Taylor from the University of Texas Health Science Center at San Antonio analyze recent publications describing evidence-based ART adherence interventions and how they can be tailored to specific situations to increase effectiveness.
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Volume 4, Issue 8
While newer antiviral agents like darunavir and the integrase strand transfer inhibitor (INSTI) dolutegravir have shown great efficacy, recent postmarketing surveillance has identified important adverse effects not found in the clinical trial populations.
In this issue, Dr. Cody Chastain from the Division of Infectious Diseases at Vanderbilt University Medical Center discusses how these new findings can impact the clinical use of these new agents.
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Volume 4, Issue 6.
Linking high-risk populations like PWIDs (people who inject drugs) and MSM (men who have sex with men) to effective HIV care requires overcoming complex barriers unique to these groups.
In this issue, two of the directors from Boston’s Health Care for the Homeless Program, Dr. Jennifer Brody, Director of HIV Services and ANP Marguerite Beiser, Director of HCV Services, discuss the clinical aspects of addressing these challenges.
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Volume 4, Issue 4.
The incidence of the metabolic complications common in people with HIV infection — bone disease, weight gain, cardiovascular disease, and liver disease — is increasing as improved antiretroviral therapies create longer lifespans.
In this issue, Dr. Suman Srinivasa and nurse practitioner Kathleen Fitch from Harvard Medical School discuss how to identify and manage these metabolic complications to help improve outcomes and quality of life in patients living with HIV.
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Volume 4, Issue 2.
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Volume 3, Issue 8.
In this podcast Drs. Allison Agwu evaluates the specific barriers to testing and entering into care among transsexual individuals, migrant and immigrant populations, and adolescents.
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Volume 3, Issue 6.
In this podcast about ART, Dr. Rachel Simmons from Boston University School of Medicine discusses recent research that may improve clinicians' ability to more effectively and more safely manage their patients with HIV infection.
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Volume 3, Issue 4.
In this podcast, Dr. Douglas Krakower discusses pre-exposure prophylaxis and addresses provider and patient barriers to PrEP.
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Volume 3, Issue 2.
In this podcast Dr. Alysse Wurcel discusses important drug-drug interactions that may impact the treatment of ischemic heart disease in people living with HIV, medication interactions that could influence the treatment of common comorbid diseases, and potential drug-drug interactions between antiretroviral agents and common over-the-counter medications.
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Volume 2, Issue 12.
Geetanjali Chander, MD, MPH, Associate Professor of Medicine covers the important topic of HIV and Alcohol in the format of case-study scenarios for the clinical practice.
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Volume 2, Issue 10.
Shobha Swaminathan, MD, Assistant Professor of Medicine in the Divisions of Infectious Diseases at Rutgers New Jersey Medical School, covers the important topic of Current Issues in HIV/HCV Coinfection.
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Volume 2, Issue 8.
Thomas Metkus, MD, Fellow in cardiovascular medicine, covers the important topic of HIV-Associated Cardiovascular Disease in the format of case-study scenarios for the clinical practice.
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Volume 2, Issue 6.
Allison Agwu, Associate Professor of Pediatrics and Infectious Diseases, covers the important topic of Treating Youth and Young Adults with HIV Infection in the format of case-study scenarios for the clinical practice.
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Volume 2, Issue 4.
Joel Gallant, MD, MPH, Associate Medical Director of Specialty Services at Southwest CARE Center, covers the important topic of new recommendations for HAART in HIV in the format of case-study scenarios for the clinical practice.
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Volume 2, Issue 2.
Jean Anderson, MD, Professor of Gynecology and Obstetrics, and Medicine, and Jenell Coleman, MD, Assistant Professor of Gynecology and Obstetrics, and Medicine at the Johns Hopkins University School of Medicine discuss the important topic of Women and HIV in the format of case-study scenarios for the clinical practice.
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Volume 1, Issue 12.
Dr. Kenneth H. Mayer from Harvard discusses the important issues related to Pre-Exposure Prophylaxis (PrEP) in HIV-uninfected individuals at high-risk and reviews the results of several key studies that evaluated the use of PrEP.
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Volume 1, Issue 10.
Our guest author is Mark Sulkowski, MD, Professor of Medicine, Medical Director of the Viral Hepatitis Center, Division of Infectious Diseases and Gastroenterology/Hepatology at the Johns Hopkins University School of Medicine in Baltimore, Maryland.
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Volume 1, Issue 8.
Drs Justin McArthur and Bryan Smith present three patient cases on the topic of HIV-Associated Neurocognitive Disorder (HAND)
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Volume 1, Issue 6.
Dr. Todd Brown, Associate Professor of Medicine in the Division of Endocrinology and Metabolism at The Johns Hopkins University School of Medicine will explain the management of an HIV-infected person with osteoporosis, and discuss the controversies surrounding vitamin D screening and treatment.
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Volume 1, Issue 4.
Our Guest Author is Michael Mugavero, MD, Associate Professor of Medicine and Director of the Center for AIDS Research Clinical Core at the University of Alabama at Birmingham.
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Volume 1, Issue 2.
Dr. Kelly Gebo, Associate Professor of Medicine and Epidemiology at the Johns Hopkins Unviersity School of Medicine will discuss the screening of older patients for HIV risk factors. She will also explain the issues of polypharmacy in older HIV infected patients.
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