Anesthesiology Journal's podcast: Recent Episodes
Anesthesiology, the journal of the American Society of Anesthesiologists
Moderator: James P. Rathmell, M.D. Participants: Albert Garcia-Casanovas, M.H.A. and Douglas Colquhoun, M.B., M.Sc., M.P.H. Articles Discussed: Association Between Adherence to Patient Blood Management Recommendations and Postoperative Complications in Hip and Knee Arthroplasty Patient Blood Management: Moving Beyond Guidelines to Action
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Moderator: BobbieJean Sweitzer, M.D. Participants: Jessica R Ansari, M.D., M.S. and Craig M. Palmer, M.D. Articles Discussed: Uterine Tone Numeric Rating Score as an Early Indicator of Major Postpartum Hemorrhage During Cesarean Delivery: A Prospective Observational Study Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony Transcript
Creator: James P. Rathmell, M.D.
July 2025, Volume 143, Issue 1
Overview of July issue original studies.
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Moderator: James P. Rathmell, M.D. Participants: Carmen Bozic, M.D. Articles Discussed: Suzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain
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Moderator: James P. Rathmell, M.D. Participants: Rebecca L. Wu, M.D. and Max B. Kelz, M.D., Ph.D. Articles Discussed: TAK-925 (danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-Induced Respiratory Depression and Sedation Without Affecting Analgesia in Healthy Adult Males Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape Transcript
Moderator: BobbieJean, M.D. Participants: Douglas Colquhoun, M.B., M.Sc., M.P.H. and Stephan R. Thilen Articles Discussed: Neuromuscular Blockade and Antagonism in Patients with Renal Impairment: A Multicenter Retrospective Cross Sectional Study On and Off Label Use of Sugammadex in Patients with Renal Impairment in the 6 ½ Years Following FDA Approval Transcript
Creator: James P. Rathmell, M.D., M.B.A.
June 2025, Volume 142, Issue 6
Overview of June issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Daqing Ma, Ph.D. and Kate Leslie, M.B.B.S., M.D. Articles Discussed: Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial B6 or Be Sick? Pyridoxine to Prevent Postoperative Nausea and Vomiting Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Alessandro Belletti, M.D., and Samuel N. Heyman, M.D. Articles Discussed: Amino Acid Infusion for Kidney Protection in Cardiac Surgery Patients with Chronic Kidney Disease: A Secondary Analysis of the PROTECTION Trial Amino Acid Infusion for the Prevention of Acute Kidney Injury: Yet a Debatable Issue
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Moderator: James P. Rathmell, M.D. Participants: Christopher Connor, M.D., Ph.D. and Peter John Schuller, M.B.B.S., B.Sc. Articles Discussed: Developing an EEG-based model to predict awakening after cardiac arrest using partial processing with the BIS Engine Unlocking Prognostic Potential in the Postarrest Electroencephalogram
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Creator: James P. Rathmell, M.D., M.B.A.
May 2025, Volume 142, Issue 5
Overview of May issue original studies.
Creator: James P. Rathmell, M.D., M.B.A.
April 2025, Volume 142, Issue 4
Overview of April issue original studies.
Moderator: James P. Rathmell, M.D. Participants: Yuming Peng, M.D., Ph.D. and Philip Devereaux, M.D., Ph.D. Articles Discussed: Covert Perioperative Strokes in Older Patients Having Noncardiac Surgery (PRECISION): A Prospective Cohort Analysis Perioperative Covert Stroke: Acutely Asymptomatic but Not Benign Transcript
Creator: James P. Rathmell, M.D., M.B.A.
March 2025, Volume 142, Issue 3
Overview of March issue original studies.
Moderator: BobbieJean Sweitzer, M.D. Participants: Jai Darvall, Ph.D. and Tong J. Gan, M.D., M.B.A., M.H.S. Articles Discussed: Chewing Gum to Treat Postoperative Nausea and Vomiting in Female Patients: A Multicenter Randomized Trial Chewing Gum: A Viable Option as a Rescue Therapy for Postoperative Nausea and Vomiting? Transcript
Moderator: James P. Rathmell, M.D. Participants: James Hitt, M.D., Ph.D. and Mark C Bicket, M.D., Ph.D. Articles Discussed: Continuation versus Interruption of Buprenorphine/Naloxone in Adult Veterans Undergoing Surgery: Examination of Postoperative Pain and Opioid Utilization in a National Retrospective Cohort Study Building a Better Base for Keeping Buprenorphine on Board for Surgery Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Annie Xin, Ph.D., M.D. and Randall Flick, M.D., M.P.H. Articles Discussed: Neurodevelopmental Outcomes After Multiple General Anaesthetic Exposure Before Five Years Of Age – A Cohort Study Secondary Analyses: The Perils of Making Do Transcript
Creator: James P. Rathmell, M.D., M.B.A.
February 2025, Volume 142, Issue 2
Overview of February issue original studies.
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Creator: James P. Rathmell, M.D., M.B.A.
January 2025, Volume 142, Issue 1
Overview of January issue original studies.
Moderator: BobbieJean Sweitzer, M.D. Participants: Guido Mazzinari, M.D., Ph.D., M.Sc. and Snehalata Huzurbazar, Ph.D. Articles Discussed: High Positive End-expiratory Pressure (PEEP) with Recruitment Maneuvers versus Low PEEP during General Anesthesia for Surgery: A Bayesian Individual Patient Data Meta-analysis of Three Randomized Clinical Trials Bayesian Analyses Are Appearing and Are Welcome Transcript
Moderator: James P. Rathmell, M.D. Participants: Nicholas Joseph Douville, M.D., Ph.D. and Vesela P. Kovacheva, M.D., Ph.D. Articles Discussed: Polygenic Score for the Prediction of Postoperative Nausea and Vomiting: A Retrospective Derivation and Validation Cohort Study Polygenic Risk Scores: Coming to Your Operating Room? Transcript
Creator: James P. Rathmell, M.D., M.B.A.
December 2024, Volume 141, Issue 6
Overview of December issue original studies.
Moderator: BobbieJean Sweitzer, M.D. Participants: Anil Panigrahi, M.D., Ph.D. Articles Discussed: Factor Eight Inhibitor Bypass Activity Use in Cardiac Surgery: A Propensity Matched Analysis of Safety Outcomes Transcript
Moderator: James P. Rathmell, M.D. Participants: Rodney Gabriel, M.D. Articles Discussed: Paravertebral versus Pectoralis-II (Interpectoral and Pectoserratus) Nerve Blocks for Postoperative Analgesia after Non-Mastectomy Breast Surgery: A Randomized, Controlled, Observer-Masked Noninferiority Trial
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Moderator: James P. Rathmell, M.D. Participants: Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc. and Daniel I. McIsaac, M.D., M.P.H. Articles Discussed: Dexamethasone for Cardiac Surgery: A Practice Preference-Randomized Consent Comparative Effectiveness Trial Routine Innovation in Perioperative Clinical Trials: The Best Chance to Answer Our Most Important Questions? Transcript
Creator: James P. Rathmell, M.D., M.B.A.
November 2024, Volume 141, Issue 5
Overview of November issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Karim Brohi, M.D. and Richard P. Dutton, M.D., M.B.A. Articles Discussed: Correction of Trauma-induced Coagulopathy by Goal-directed Therapy: A Secondary Analysis of the ITACTIC Trial Tactics versus Strategy in Trauma Resuscitation Transcript
Moderator: James P. Rathmell, M.D. Participants: Daniele De Luca M.D., Ph.D. and David Tingay, M.B.B.S., Ph.D. Articles Discussed: Global and Regional Heterogeneity of Lung Aeration in Neonates with Different Respiratory Disorders: A Physiological, Observational Study Lung Ultrasound and Regional Heterogeneity: A Bedside Solution to an Under-Recognized Problem?
Creator: James P. Rathmell, M.D., M.B.A.
October 2024, Volume 141, Issue 4
Overview of October issue original studies.
Moderator: BobbieJean Sweitzer, M.D. Participants: Sebastian J. Corlette, M.B.B.S. and Isabelle Constant, Ph.D., M.D. Articles Discussed: Changes in the Term Neonatal Electroencephalogram with General Anesthesia – A Systematic Review with Narrative Synthesis Challenge of Neonatal Anesthesia: Which Optimal EEG Target? Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Lisa M. Einhorn, M.D. and Charles B. Berde, M.D., Ph.D. Articles Discussed: Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial Improving Pain Management After Tonsillectomy Transcript
Creator: James P. Rathmell, M.D., M.B.A.
September 2024, Volume 141, Issue 3
Overview of September issue original studies.
Moderator: James P. Rathmell, M.D. Participants: Steven L. Shafer, M.D. and David Clark, M.D., Ph.D. Articles Discussed: Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial Sweeping Away Dyspnea A Spicy New Treatment for Postoperative Pain Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Andrew Bowdle, M.D., Ph.D. and Sorin J. Brull, M.D. Articles Discussed: Accuracy and Precision of Three Acceleromyographs, Three Electromyographs and a Mechanomyograph Measuring the Train-of-Four Ratio in the Absence of Neuromuscular Blocking Drugs Vital Sign Data Quality: Not Just a Retrospective Research Problem Accuracy and Precision of Acceleromyography, Electromyography and Mechanomyography: Time to Re-think What We Know Transcript
Creator: James P. Rathmell, M.D., M.B.A.
August 2024, Volume 141, Issue 2
Overview of August issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Mathias Maleczek, M.D., and Patrick J. McCormick, M.D., M.Eng. Articles Discussed: A Comparison of Five Algorithmic Methods and Machine Learning Pattern Recognition for Artifact Detection in Electronic Records of Five Different Vital Signs: A Retrospective Analysis Vital Sign Data Quality: Not Just a Retrospective Research Problem Transcript
Creator: James P. Rathmell, M.D., M.B.A.
July 2024, Volume 141, Issue 1
Overview of July issue original studies.
Moderator: James P. Rathmell, M.D. Participants: Côme Bureau, M.D., Ph.D. and Nikolaos J. Skubas, M.D. Articles Discussed: Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients: A Pilot Study Sweeping Away Dyspnea
Moderator: BobbieJean Sweitzer, M.D. Participants: Aurora N. Quaye, M.D. and Douglas A. Colquhoun, M.B.Ch.B., M.Sc., M.P.H. Articles Discussed: Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study Does Propofol Improve Polyp Detection during Colonoscopy? The Promise and Peril of Clinical Registry Data
Moderator: James P. Rathmell, M.D. Participants: Albert Dahan, M.D., Ph.D., and Thomas K. Henthorn, M.D. Articles Discussed: Reversal of Propofol-induced Depression of the Hypoxic Ventilatory Response by BK-channel Blocker ENA-001: A Randomized Controlled Trial Reversal for Respiratory Depression: Let’s Take a Breath! Transcript
Creator: James P. Rathmell, M.D., M.B.A.
June 2024, Volume 140, Issue 6
Overview of June issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Jessica C. Martin, Ph.D., B.Sc. and Jerry Chao, M.D., M.Sc. Articles Discussed: The Topographical Features of Pediatric Electroencephalography during High Initial Concentration Sevoflurane for Inhalational Induction of Anesthesia A Window into the Developing Brain: Toward a Deeper Understanding of Pediatric Anesthesia Transcript
Creator: James P. Rathmell, M.D., M.B.A.
May 2024, Volume 140, Issue 5
Overview of May issue original studies.
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Moderator: James P. Rathmell, M.D. Participants: Faraj Abdallah, M.D. and Michael R. Fettiplace, M.D., Ph.D. and Ashraf S. Habib, M.D., M.B.B.Ch., M.Sc., M.H.Sc. and Jonathan Slonin, M.D., M.B.A. Articles Discussed: Analgesic Effectiveness of Liposomal Bupivacaine versus Plain Local Anesthetics for Abdominal Fascial Plane Blocks: A Systematic Review and Meta-analysis of Randomized Trials Meta-analyses of Randomized Clinical Trials in Postsurgical Pain: Verify before Trusting Liposomal Bupivacaine for Abdominal Fascial Plane Blocks: No Evidence or Lack of Relevant Evidence? Liposomal Bupivacaine, Scientific Evidence, and the Clinician’s Conundrum Liposomal Bupivacaine’s Plausibility Fails to Translate
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Creator: James P. Rathmell, M.D., M.B.A.
April 2024, Volume 140, Issue 4
Overview of April issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Maximilian Sebastian Schaefer, M.D. and Amy Gaskell, M.B.Ch.B., Ph.D. Articles Discussed: Intraoperative Use of Phenylephrine versus Ephedrine and Postoperative Delirium: A Multicenter Retrospective Cohort Study Caveat Emptor: Vasopressor Choice and Postoperative Delirium—A Complex Relationship Explored Transcript
Moderator: James P. Rathmell, M.D. Participants: Anahi Perlas, M.D. and Mark Warner, M.D. Articles Discussed: Baseline Gastric Volume in Fasting Diabetic Patients Is Not Higher than That in Nondiabetic Patients: A Cross-sectional Noninferiority Study Diabetic Patients, Assessment of Preoperative Gastric Contents, and Potential Reduction of Risk of Pulmonary Aspiration Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Pavel S. Roshanov, M.D., M.Sc. Articles Discussed: One-Year Outcomes After Discharge from Noncardiac Surgery and Association Between Pre-Discharge Complications and Death After Discharge: Analysis of the VISION Prospective Cohort Study Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Scott Segal, M.D., M.H.C.M. and Jeffrey B. Cooper, Ph.D. Articles Discussed: A Quality Improvement Initiative to Reduce Adverse Effects of Transitions of Anesthesia Care on Postoperative Outcomes: A Retrospective Cohort Study Anesthesia Needs to Lead the Way in Safety—Again—through the Universal Adoption of Structured Handoffs Transcript
Moderator: James P. Rathmell, M.D. Participants: Mark D. Neuman, M.D., M.Sc. and Elizabeth L. Whitlock, M.D., M.Sc. Articles Discussed: Long-term Outcomes with Spinal versus General Anesthesia for Hip Fracture Surgery: A Randomized Trial REGAINing the Freedom to Choose Insensibility for Hip Fracture Surgery Transcript
Creator: James P. Rathmell, M.D., M.B.A.
March 2024, Volume 140, Issue 3
Overview of March issue original studies.
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Creator: James P. Rathmell, M.D., M.B.A.
February 2024, Volume 140, Issue 2
Overview of February issue original studies.
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Moderator: James P. Rathmell, M.D. Participants: Mattia Busana, M.D. and Marcos F. Vidal Melo, M.D., Ph.D. Articles Discussed: The Causes of Hypoxemia of COVID-19 ARDS: A Combined MIGET and Dual-Energy CT Study Structure–Function Relationships Determining Hypoxemia in COVID-19 Acute Respiratory Distress Syndrome
Moderator: BobbieJean Sweitzer, M.D. Participants: Michael F. Aziz, M.D. and Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc. Articles Discussed: Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study COVID-19 and Surgery: Getting Back to Business Transcript
Moderator: James P. Rathmell, M.D. Participants: Thomas Langer, M.D. and David A. Story, M.B.B.S., B.Med.Sci., M.D. Articles Discussed: Combining the Physical-Chemical Approach with Standard Base Excess to Understand the Compensation of Respiratory Acid-Base Derangements: An Individual Participant Meta-Analysis Approach to Data from Multiple Canine and Human Experiments Respiratory Changes and Acid–Base Compensation: Watch the Salt Transcript
Creator: James P. Rathmell, M.D.
January 2024, Volume 140, Issue 1
Overview of January issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Jean Guglielminotti, M.D., Ph.D. Articles Discussed: Association of Labor Neuraxial Analgesia with Maternal Blood Transfusion Transcript
Creator: James P. Rathmell, M.D., M.B.A.
December 2023, Volume 139, Issue 6
Overview of December issue original studies.
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Moderator: James P. Rathmell, M.D. Participants: Stephan Frangakis, M.D., Ph.D. and Carolina B. Meloto, D.D.S., Ph.D. Articles Discussed: Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses Genetics of Postsurgical Pain: Where Do We Go from Here? Transcript
Moderator: James P. Rathmell, M.D. Participants: Phillip Vlisides, M.D. and Patrick L. Purdon, Ph.D. Articles Discussed: Electroencephalographic Biomarkers, Cerebral Oximetry, and Postoperative Cognitive Function in Adult Non-Cardiac Surgical Patients: a Prospective Cohort Study Charting a Cognitive Course: Can Electroencephalographic or Oximetry Biomarkers Predict Postoperative Cognitive Function? Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Anjali A. Dixit, M.D., M.P.H. and Avery Tung, M.D. Articles Discussed: Association Between “Balance Billing” Legislation and Anesthesia Payments in California: A Retrospective Analysis Balanced Billing Legislation and the Invisible Hand of Adam Smith Transcript
Creator: James P. Rathmell, M.D., M.B.A.
November 2023, Volume 139, Issue 5
Overview of November issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Evan D. Kharasch, M.D., Ph.D., and Paul S. Myles, M.B., B.S., M.P.H., M.D., D.Sc., F.C.A.I., F.A.N.Z.C.A., F.A.H.M.S. Articles Discussed: Intraoperative Methadone in Next-day Discharge Outpatient Surgery: A Randomized, Double-blinded, Dose-finding Pilot Study Consideration of Methadone as an Analgesic Option for Short-stay Surgery Transcript
Moderator: James P. Rathmell, M.D.
Participants: Allan F. Simpao, M.D., M.B.I., and Caleb Ing, M.D., M.S.
Articles Discussed:
Anesthesia and Sedation Exposure and Neurodevelopmental Outcomes in Infants Undergoing Congenital Cardiac Surgery: A Retrospective Cohort Study
Developmental Anesthesia Neurotoxicity: Lessons from the Heart
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Creator: James P. Rathmell, M.D., M.B.A.
October 2023, Volume 139, Issue 4
Overview of October issue original studies.
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Moderator: James Rathmell, M.D.
Participants: Joerg Krebs, M.D. and Hermann Wrigge, M.D., Ph.D.
Articles Discussed:
Individualized Positive End-Expiratory Pressure Titration Strategies in Superobese Patients Undergoing Laparoscopic Surgery: Prospective and Non-Randomized Crossover Study
Pressure for High PEEP in Obese Surgical Patients is Growing
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Alexandre Mansour, M.D., Ph.D.
Articles Discussed:
Combined Platelet and Red Blood Cell Recovery During On-Pump Cardiac Surgery Using Same™ By I-SEP Autotransfusion Device: A First-In-Human Non-Comparative Study (I-TRANSEP Study)
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Creator: James P. Rathmell, M.D.
September 2023, Volume 139, Issue 3
Overview of September issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Daniel I. McIsaac, M.D., M.P.H.
Articles Discussed:
Attributable Perioperative Cost of Frailty After Major, Elective Non-cardiac Surgery: A Population-based Cohort Study
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Moderator: James Rathmell, M.D.
Participants: Karsten Bartels, M.D., Ph.D., M.B.A. and Chad Michael Brummett, M.D.
Articles Discussed:
Best Practice Alerts Informed by Inpatient Opioid Intake to Reduce Opioid Prescribing after Surgery (PRIOR): A Cluster Randomized Multiple Crossover Trial
Best Practice Alerts: A Poke in the Eye or an Efficient Method for Safer Prescribing?
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Creator: James P. Rathmell, M.D.
August 2023, Volume 139, Issue 2
Overview of August issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Robert S. White, M.D., M.S. and Warren S. Sandberg, M.D., Ph.D.
Articles Discussed:
Antiemetic Administration and its Association with Race: A Retrospective Cohort Study Association Multicenter Study
“People, We Have a Problem”
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Moderator: BobbieJean Sweitzer, M.D. Participants: Konrad Meissner, M.D. Articles Discussed: Morphine and Hydromorphone Effects, Side Effects and Variability – a Crossover Study in Human Volunteers Transcript
Moderator: James Rathmell, M.D. Participants: Andrew Bowdle, M.D., Ph.D. and Michael M. Todd, M.D. Articles Discussed: A Dose-Finding Study of Sugammadex for Reversal of Rocuronium in Cardiac Surgery Patients and Postoperative Monitoring for Recurrent Paralysis Sugammadex is Not a Silver Bullet: Caveats Regarding Unmonitored Reversal Transcript
Creator: James P. Rathmell, M.D.
July 2023, Volume 139, Issue 1
Overview of July issue original studies.
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Moderator: James Rathmell, M.D. Participants: Kai Kuck, Ph.D. and Karim Shiraz Ladha, M.D. Articles Discussed: Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery Under General Anesthesia: A Prospective Cohort Association Multicenter Study Uncoupling Pain and Opioid Use after Surgery Transcript
Moderator: James Rathmell, M.D. Participants: Mathias Maagaard, M.D. Articles Discussed: Perineural and Systemic Dexamethasone And Ulnar Nerve Block Duration A Randomized, Blinded, Placebo-controlled Trial in Healthy Volunteers Transcript
Creator: James P. Rathmell, M.D.
June 2023, Volume 138, Issue 6
Overview of June issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Emmanuelle Duceppe, M.D. Ph.D. Articles Discussed: Association of Preoperative Growth Differentiation Factor-15 Concentrations and Postoperative Cardiovascular Events after Major Noncardiac Surgery Transcript
Creator: James P. Rathmell, M.D.
May 2023, Volume 138, Issue 5
Overview of May issue original studies.
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Moderator: James Rathmell, M.D. Participants: Philip J. Peyton, M.D., Ph.D., M.B.B.S. and Marcelo Gama de Abreu, M.D., M.Sc., Ph.D. Articles Discussed: Postoperative Pulmonary Complications in the ENIGMA II Trial: A Post Hoc Analysis Nitrous Oxide and Postoperative Pulmonary Complications: Conflicting Evidence Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Aman Mahajan, M.D., Ph.D. and Karsten Bartels, M.D., Ph.D., M.B.A. Articles Discussed: GABAergic Signaling During Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model Modulating the Cardiac Autonomic Nervous System: Stay Close to My Heart or Keep Your Distance? Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
April 2023, Volume 138, Issue 4
Overview of April issue original studies.
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Moderator: James Rathmell, M.D. Participants: Leo M. A. Heunks, M.D., Ph.D. and Ewan Christopher Goligher, M.D., Ph.D. Articles Discussed: Performance of Noninvasive Airway Occlusion Maneuvers to Assess Lung Stress and Diaphragm Effort in Mechanically Ventilated Critically Ill Patients Monitoring Respiratory Effort and Lung-Distending Pressure Non-Invasively During Mechanical Ventilation: Ready for Prime Time Transcript
Moderator: BobbieJean Sweitzer, M.D. Participants: Simone Gattarello, M.D., Ph.D. and Daniel R. Calabrese, M.D. Articles Discussed: Mechanical Power Ratio and Respiratory Treatment Escalation in COVID-19 Pneumonia: A Secondary Analysis of a Prospectively Enrolled Cohort The Paradox of Power: Dynamic Tools to Predict Respiratory Failure in Spontaneously Breathing Patients Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
March 2023, Volume 138, Issue 3
Overview of March issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Jamie Privratsky, M.D., Ph.D. Articles Discussed: Postoperative Acute Kidney Injury by Age and Sex: A Retrospective Cohort Association Study Transcript
Moderator: James Rathmell, M.D. Participants: Naheed Kabirudeen Jivraj, M.B.B.S., M.Sc. Articles Discussed: Nonopioid Analgesic Prescriptions Filled after Surgery among Older Adults in Ontario, Canada: A Population-based Cohort Study Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
February 2023, Volume 138, Issue 2
Overview of February issue original studies.
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Moderator: BobbieJean Sweitzer, M.D. Participants: Daniel Sessler, M.D. and Ana Fernandez-Bustamante, M.D., Ph.D. Articles Discussed: Perioperative Supplemental Oxygen and Postoperative Nausea and Vomiting: Subanalysis of a Trial, Systematic Review, and Meta-analysis Adjust Intraoperative Oxygen Therapy for Oxygenation Reasons Only! Transcript
Moderator: James Rathmell, M.D. Participants: Daniel Rubin, M.D.,M.S. and Jessica Spence, M.D., Ph.D. Articles Discussed: Preoperative b-Blocker Therapy and Stroke or Major Adverse Cardiac Events in Major Abdominal Surgery: A Retrospective Cohort Study Beta Blockade before Noncardiac Surgery: The Devil is in the Details Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
January 2023, Volume 138, Issue 1
Overview of January issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Min-Hsin Huang, M.D., M.S. and James Blum, M.D.
Articles Discussed:
Validation of a Deep Learning-Based Automatic Detection Algorithm for Measurement of Endotracheal Tube to Carina Distance on Chest Radiographs
Collaborative Artificial Intelligence in Practice: The Next Steps
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Moderator: James Rathmell, M.D.
Participants: Daniel Sessler, M.D.
Articles Discussed:
Risk Stratification Index 3.0, a Broad Set of Models for Predicting Adverse Events During and After Hospital Admission
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Creator: Evan D. Kharasch, M.D., Ph.D.
December 2022, Volume 137, Issue 6
Overview of December issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Marla Ferschl, M.D. and Britta Sylvia von Ungern-Sternberg, M.D., Ph.D.
Articles Discussed:
Wildfire Smoke Exposure is Associated with Adverse Respiratory Events Under General Anesthesia in At-Risk Pediatric Patients
If We Destroy Nature – We Destroy Ourselves
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Moderator: James Rathmell, M.D.
Participants: John Finneran IV, M.D. and Kristin Schreiber, M.D., Ph.D.
Articles Discussed:
Preoperative Ultrasound-Guided Percutaneous Cryoneurolysis for the Treatment of Pain following Mastectomy: A Randomized, Participant- and Observer-Masked, Sham-Controlled Study
Cryoneurolysis: Interest and Caution
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Creator: Evan D. Kharasch, M.D., Ph.D.
November 2022, Volume 137, Issue 5
Overview of November issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: John Fiadjoe, M.D. and Allan Simpao, M.D., M.B.I.
Articles Discussed:
Sedation versus General Anesthesia for Tracheal Intubation in Children with Difficult Airways: A Cohort Study from the Pediatric Difficult Intubation Registry
Walk a Tightrope or Burn a Bridge?: Sedation versus General Anesthesia for Intubation of a Pediatric Difficult Airway
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Moderator: James Rathmell, M.D.
Participants: Alparslan Turan, M.D. and Marcos Vidal Melo, M.D., Ph.D.
Articles Discussed:
Tidal Volume and Positive End-Expiratory Pressure and Postoperative Hypoxemia during General Anesthesia: A Single Center Multiple Cross-over Factorial Cluster Trial
A Lung-Unanswered Question
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Creator: Evan D. Kharasch, M.D., Ph.D.
October 2022, Volume 137, Issue 4
Overview of October issue original studies.
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Moderator: BobbieJean Sweitzer, M.D.
Participants: Mats Enlund, M.D., Ph.D.
Articles Discussed:
Volatile versus Propofol General Anesthesia and Long-term Survival after Breast Cancer Surgery: A National Registry Retrospective Cohort Study
Transcript
Moderator: James Rathmell, M.D.
Participants: Charles H. Brown IV, M.D.
Articles Discussed:
Perioperative Neurofilament Light Plasma Concentrations and Cognition before and after Cardiac Surgery: A Prospective Nested Cohort Study
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
September 2022, Volume 137, Issue 3
Overview of December issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Eric Sun, M.D., Ph.D. and Daniel McIsaac, M.D., M.P.H.
Articles Discussed:
Surgeon Variation in Perioperative Opioid Prescribing and Medium or Long Term Opioid Utilization After Total Knee Arthroplasty: A Cross-Sectional Analysis
Postoperative Opioid Prescribing: Finding the Balance
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
August 2022, Volume 137, Issue 2
Overview of August issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Ian Yuan, M.D.
Articles Discussed:
Isoelectric Electroencephalography in Infants and Toddlers During Anesthesia for Surgery: An International Observational Study
Transcript
Moderator: James Rathmell, M.D.
Participants: Maximilian Sebastian Schaefer, M.D. and Marcelo Gama de Abreu, M.D., MS.c., Ph.D.
Articles Discussed:
Mechanical Power during General Anesthesia and Postoperative Respiratory Failure: A Multicenter Retrospective Cohort Study
Mechanical Power: Correlate or Cause of Ventilator-induced Lung Injury?
Transcript
Moderator: James Rathmell, M.D.
Participants: Shiroh Isono, M.D. and David R. Hillman, M.D.
Articles Discussed:
Combination Therapy of High-flow Nasal Cannula and Upper-body Elevation for Postoperative Sleep-disordered Breathing: Randomized Crossover Trial
Is Continuous Positive Airway Pressure All There Is? Alternative Perioperative Treatments for Obstructive Sleep Apnea
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
July 2022, Volume 137, Issue 1
Overview of July issue original studies.
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
June 2022, Volume 136, Issue 6
Overview of June issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Balachundhar Subramaniam, M.D., M.P.H.
Articles Discussed:
Intraoperative Hypotension and Acute Kidney Injury, Stroke, and Mortality during and outside Cardiopulmonary Bypass: A Retrospective Observational Cohort Study
Transcript
Moderator: James Rathmell, M.D.
Participants: Wade A. Weigel, M.D. and Meghan B. Lane-Fall, M.D., M.S.H.P.
Articles Discussed:
Quantitative Neuromuscular Monitoring in Clinical Practice: A Professional Practice Change Initiative
What Anesthesiology Has to Learn from Implementation Science and Quality Improvement
Transcript
Moderator: James Rathmell, M.D.
Participants: Ashraf S. Habib, M.B.B.Ch., M.Sc., M.H.Sc. and Scott Segal, M.D., M.H.C.M.
Articles Discussed:
Quality of Labor Analgesia with Dural Puncture Epidural versus Standard Epidural Technique in Obese Parturients: A Double-blind Randomized-controlled Study
Dural Puncture Epidural for Labor Analgesia: is it Really an Improvement Over Conventional Labor Epidural Analgesia?
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Garrett W. Burnett, M.D. and Kevin K. Tremper, Ph.D., M.D.
Articles Discussed:
Self-reported Race/Ethnicity and Intraoperative Occult Hypoxemia: A Retrospective Cohort Study
The Pulse Oximeter Is Amazing, but Not Perfect
Transcript
Moderator: James Rathmell, M.D.
Participants: Christian Sylvest Meyhoff, M.D., Ph.D. and Peter Nagele, M.D., M.Sc.
Articles Discussed:
Hyperoxia and Antioxidants for Myocardial Injury in Noncardiac Surgery: A 2x2 Factorial Blinded Randomized Clinical Trial
The Importance of Definitive Trials: the VIXIE Trial
Transcript
Moderator: James Rathmell, M.D.
Participants: Hélène Beloeil, M.D., Ph.D.
Articles Discussed:
General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
May 2022, Volume 136, Issue 5
Overview of May issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Aaron A. Berg, D.O.
Articles Discussed:
Evaluation of Diaphragmatic Function after Interscalene Block with Liposomal Bupivacaine: A Randomized Controlled Trial
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: David H. Kim, M.D.
Articles Discussed:
Interscalene Brachial Plexus Block with Liposomal Bupivacaine versus Standard Bupivacaine with Perineural Dexamethasone: A Noninferiority Trial
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
April 2022, Volume 136, Issue 4
Overview of April issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Cecilia Canales, M.D., M.P.H., Daniel I. McIsaac, M.D., M.P.H., F.R.C.P.C.
Articles Discussed:
Preoperative Point-of-Care Ultrasound to Identify Frailty and Predict Postoperative Outcomes: A Diagnostic Accuracy Study
Preoperative Frailty Assessment: An Opportunity to Add Value to Perioperative Care
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
March 2022, Volume 136, Issue 3
Overview of March issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Sabine Nabecker, M.D. and Allan Simpao, M.D., M.B.I.
Articles Discussed:
Carbon Dioxide Changes during High-flow Nasal Oxygenation in Apneic Patients: A Single-center Randomized Controlled Noninferiority Trial
Can We Finally Take the “VE” Out of THRIVE?
Transcript
Moderator: James Rathmell, M.D.
Participants: Ross Davenport, Ph.D. and Robert Medcalf, B.Sc.(Hons), Ph.D.
Articles Discussed:
Temporal Transitions in Fibrinolysis after Trauma: Adverse Outcome Is Principally Related to Late Hypofibrinolysis
Fibrinolysis and Trauma Outcomes
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
Feburary 2022, Volume 136, Issue 2
Overview of February issue original studies.
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
January 2022, Volume 136, Issue 1
Overview of January issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Forbes McGain, F.A.N.Z.C.A, F.C.I.C.M., Ph.D. and Michel M. R. F. Struys, M.D., Ph.D., F.R.C.A.
Articles Discussed:
Carbon Footprint of General, Regional, and Combined Anesthesia for Total Knee Replacements
Environmental Footprint of Anesthesia: More than Inhaled Anesthetics!
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
December 2021, Volume 135, Issue 6
Overview of December issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Charles H. Brown, IV, M.D., M.H.S. and Pratik P. Pandharipande, M.D., M.Sc.
Articles Discussed:
Spinal Anesthesia with Targeted Sedation Based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial
Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Charles H. Brown, IV, M.D., M.H.S. and Pratik P. Pandharipande, M.D., M.Sc.
Articles Discussed:
Spinal Anesthesia with Targeted Sedation Based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial
Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium
Moderator: BobbieJean Sweitzer, M.D.
Participants: Gavin Hamilton, M.D., M.Sc.
Articles Discussed:
Persistent Postoperative Opioid Prescription Fulfillment and Peripheral Nerve Blocks for Ambulatory Shoulder Surgery: A Retrospective Cohort Study
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
November 2021, Volume 135, Issue 5
Overview of November issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Avery Tung, M.D. and editorialist Warren S. Sandberg, M.D., Ph.D.
Articles Discussed:
December Is Coming: A Time Trend Analysis of Monthly Variation in Adult Elective Anesthesia Caseload across Florida and Texas Locations of a Large Multistate Practice
December Is for Congregation, Celebration, Operation, Recuperation
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
October 2021, Volume 135, Issue 4
Overview of October issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Jin-Tae Kim, M.D., Ph.D. and editorialist Jorge A. Gálvez, M.D., M.B.I.
Articles Discussed:
Smart Glasses for Radial Arterial Catheterization in Pediatric Patients: A Randomized Clinical Trial
Augmenting the Anesthesiologist's Cockpit with Head-mounted Displays for Image-guided Procedures: Are We There Yet?
Transcript
Moderator: James Rathmell, M.D.
Participants: Kerstin Kolodzie, M.D., Ph.D., M.A.S. and editorialist Duminda Wijeysundera, M.D., Ph.D., F.R.C.P.C.
Articles Discussed:
Perioperative Normal Saline Administration and Delayed Graft Function in Patients Undergoing Kidney Transplantation: A Retrospective Cohort Study
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
September 2021, Volume 135, Issue 2
Overview of September issue original studies.
Transcript
Moderator:James Rathmell, M.D.
Participants: Natalie A. Silverton, M.D., F.R.C.P.C., F.A.S.E. and editorialist Mark Stafford-Smith, M.D., C.M., F.R.C.P.C., M.B.A.
Articles Discussed:
Noninvasive Urine Oxygen Monitoring and the Risk of Acute Kidney Injury in Cardiac Surgery
Could Trended Oxygen Partial Pressure in the Urine Be the “ST Segment” Kidney Monitor We’ve Been Looking For?
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
August 2021, Volume 135, Issue 2
Overview of August issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Alexandre Joosten, M.D., Ph.D. and editorialist David A. Story, M.D., F.A.N.Z.C.A.
Articles Discussed:
Computer-assisted Individualized Hemodynamic Management Reduces Intraoperative Hypotension in Intermediate- and High-risk Surgery: A Randomized Controlled Trial
Computer-assisted Anesthesia Care: Avoiding the Highway to HAL
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Mark A. Warner, M.D. and editorialist Anahi Perlas, M.D., F.R.C.P.C
Articles Discussed:
Pulmonary Aspiration of Gastric Contents: A Closed Claims Analysis
Pulmonary Aspiration of Gastric Contents: Can We Improve Patient Outcomes?
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Jerrold Levy, M.D., and Jean M. Connors, M.D.
Transcript
Moderator:James Rathmell, M.D.
Participants: Andres Laserna, M.D., Laurent G. Glance, M.D. and Mark D. Neuman, M.D., M.Sc.
Articles Discussed:
Levels of Evidence Supporting the North American and European Perioperative Care Guidelines for Anesthesiologists between 2010 and 2020: A Systematic Review
Clinical Practice Guidelines in Anesthesiology: Adjusting Our Expectations
Creator: Evan D. Kharasch, M.D., Ph.D.
July 2021, Volume 135, Issue 1
Overview of July issue original studies.
Transcript
Moderator:BobbieJean Sweitzer, M.D.
Participants: Jashvant Poeran, M.D., Ph.D., Calin S. Moucha, M.D and editorialist Sachin Kheterpal, M.D., M.B.A.
Article Discussed:
- Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients
- Tranexamic Acid in High-risk Arthroplasty Patients: How Will We Adapt to Evolving Evidence?
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
June 2021, Volume 134, Issue 6
Overview of June issue original studies.
Transcript
Moderator:James Rathmell, M.D.
Participants: Lena S. Sun, M.D.; Nicholas A. Davis, M.D., and editorialist Laszlo Vutskits, M.D., Ph.D.
Articles Discussed:
- Ultrasound Evaluation of Gastric Emptying Time in Healthy Term Neonates after Formula Feeding
- Neonatal Preoperative Fasting: Time for a Change?
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Michael McManus, M.D., M.P.H. and Alan Jay Schwartz, M.D., M.S.Ed.
Articles Discussed:
Availability of Inpatient Pediatric Surgery in the United States
Availability of Inpatient Pediatric Surgery: Implications for Planning Pediatric Anesthesiology Education
Creator: Evan D. Kharasch, M.D., Ph.D.
May 2021, Volume 134, Issue 5
**Overview of May issue original studies.
Transcript**
Moderator: BobbieJean Sweitzer, M.D.
Participants: Glenn S. Murphy, M.D., and J. David Clark, M.D., Ph.D.
Articles Discussed:
Perioperative Methadone and Ketamine for Postoperative Pain Control in Spinal Surgical Patients: A Randomized, Double-blind, Placebo-controlled Trial
Methadone and Ketamine: Boosting Benefits and Still More to Learn
Transcript
Moderator:James Rathmell, M.D.
Participants: Amy E. Vinson, M.D., and Steve Alan Hyman, M.D., M.M.
Articles Discussed:
Burnout Rate and Risk Factors among Anesthesiologists in the United States
Burnout: The “Other” Pandemic
Transcript
Moderator: James Rathmell, M.D.
Participants: Helene Beloeil, M.D., M.P.H., and Evan Kharasch, M.D., Ph.D.
Articles Discussed:
Balanced Opioid-free Anesthesia with Dexmedetomidine versus Balanced Anesthesia with Remifentanil for Major or Intermediate Noncardiac Surgery: The Postoperative and Opioid-free Anesthesia (POFA) Randomized Clinical Trial
Opioid-free Anesthesia: Time to Regain Our Balance
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
April 2021, Volume 134, Issue 4
Overview of April issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Daniel McIsaac, M.D., M.P.H.
Articles Discussed:
Complications as a Mediator of the Perioperative Frailty–Mortality Association: Mediation Analysis of a Retrospective Cohort
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Christoph Heinz, M.D. and Klaus Görlinger, M.D.
Articles Discussed:
Greater Fibrinolysis Resistance but No Greater Platelet Aggregation in Critically Ill COVID-19 Patients
COVID-19–associated Coagulopathy: Less Fibrinolysis Can Be More Harmful!
Transcript
Moderator: James Rathmell, M.D.
Participants: Patrick J. Tighe, M.D., M.S., Terrie Vasilopoulos, Ph.D, and Kristin L. Schreiber, M.D., Ph.D.
Articles Discussed:
Patient and Procedural Determinants of Postoperative Pain Trajectories
Personalization over Protocolization: Embracing Diversity of Pain Trajectories after Surgery
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
March 2021, Volume 134, Issue 3
Overview of March issue original studies. Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Shahzad Shaefi, M.D.
Article Discussed:
Intraoperative Oxygen Concentration and Neurocognition after Cardiac Surgery: A Randomized Clinical Trial
Transcript
Moderator:James Rathmell, M.D.
Participants: Faraj W. Abdallah, M.D., M.Sc. and Mary Ellen McCann, M.D.
Article Discussed:
Perineural Liposomal Bupivacaine Is Not Superior to Nonliposomal Bupivacaine for Peripheral Nerve Block Analgesia: A Systematic Review and Meta-analysis
Liposomal Bupivacaine: Effective, Cost-effective, or (Just) Costly?
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
February 021, Volume 134, Issue 2
Overview of February issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Stephen J. Gleich, M.D., and Andrew Davidson, M.B.B.S., M.D., F.A.N.Z.C.A., F.A.H.M.S.
Article Discussed:
Major Short-term Complications of Arterial Cannulation for Monitoring in Children
Complication Rates in Anesthesia: Why Retrospective Studies May Be Extraordinary
Moderator:James Rathmell, M.D.
Participants: Faraj W. Abdallah, M.D., M.Sc.
Article Discussed:
Postoperative Analgesic Effectiveness of Quadratus Lumborum Block for Cesarean Delivery under Spinal Anesthesia: A Systematic Review and Meta-analysis
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
January 2021, Volume 134, Issue 1
Overview of January issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Geir Strandenes, M.D. and Beth H. Shaz, M.D.
Articles Discussed:
A Pilot Trial of Platelets Stored Cold versus at Room Temperature for Complex Cardiothoracic Surgery
Warming Up to Cold-stored Platelets
Moderator: BobbieJean Sweitzer, M.D.
Participants: Kamal Maheshwari, M.D., M.P.H. and Charles W. Hogue, M.D.
Articles Discussed:
Hypotension Prediction Index for Prevention of Hypotension during Moderate- to High-risk Noncardiac Surgery: A Pilot Randomized Trial
Preventing Intraoperative Hypotension: Artificial Intelligence versus Augmented Intelligence?
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
December 2020, Volume 133, Issue 6
Overview of December issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Josef Briegel, M.D and Bernd Saugel, M.D.
Articles Discussed:
Clinical Evaluation of a High-fidelity Upper Arm Cuff to Measure Arterial Blood Pressure during Noncardiac Surgery
Hydraulic Coupling: A New Method for Noninvasive Intermittent Blood Pressure Monitoring
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Graham J. Walkden, M.B.Ch.B., Hannah Gill, F.R.C.A., Ph.D. and Andrew J. Davidson, M.B.B.S., M.D., F.A.N.Z.C.A., F.A.H.M.S .
Articles Discussed:
Early Childhood General Anesthesia and Neurodevelopmental Outcomes in the Avon Longitudinal Study of Parents and Children Birth Cohort
Anesthesia in Childhood and Neurodevelopmental Outcome: The Ongoing Hunt for a Phenome
Creator: Evan D. Kharasch, M.D., Ph.D.
November 2020, Volume 133, Issue 5
Overview of November issue original studies.
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
October 2020, Volume 133, Issue 4
Overview of October issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: S. Patrick Bender, M.D., M.S.H.S., and Marcos F. Vidal Melo, M.D., Ph.D .
Articles Discussed:
Body Habitus and Dynamic Surgical Conditions Independently Impair Pulmonary Mechanics during Robotic-assisted Laparoscopic Surgery: A Cross-Sectional Study
Lung Mechanics of the Obese Undergoing Robotic Surgery and the Pursuit of Protective Ventilation
Moderator: James Rathmell, M.D.
Participants: Felix van Lier, M.D., Ph.D.
Article Discussed:
Postoperative Hypotension after Noncardiac Surgery and the Association with Myocardial Injury
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology September 2020, Volume 133, Issue 3
Overview of September issue original studies.
Moderator: BobbieJean Sweitzer, M.D.
Participants: Allan F. Simpao, M.D., M.B.I. and Laszlo Vutskits, M.D., Ph.D.
Articles Discussed:
- Preoperative Fluid Fasting Times and Postinduction Low Blood Pressure in Children: A Retrospective Analysis
- Fluid Fasting in Children: Solid Science?
Creator: Evan D. Kharasch, M.D., Ph.D.
Anesthesiology August 2020, Volume 133, Issue 2
Overview of August issue original studies.
Transcript
Moderator:James Rathmell, M.D.
Participants: Alexis F. Turgeon, M.D., M.Sc. and Evan D. Kharasch, M.D., Ph.D.
Articles Discussed:
- Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis
- Perioperative Gabapentinoids: Deflating the Bubble
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Oluwaseun Akeju, M.D., M.M.S.C.I. and Jamie W. Sleigh, M.D.
Articles Discussed:
- Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium
- Postoperative Delirium: A Minefield of Markers and Mediators
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology July 2020, Volume 133, Issue 1
Overview of July issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Marc-Olivier Fischer, M.D., Ph.D. and Kamal Maheshwari, M.D., M.P.H.
Articles Discussed:
- Individualized Fluid Management Using the Pleth Variability Index: A Randomized Clinical Trial
- Goal-directed Therapy: Why Benefit Remains Uncertain
Transcript
Moderator: James Rathmell, M.D.
Participants: Gisèle Pickering, M.D., Ph.D., D.Pharm and J. David Clark, M.D., Ph.D.
Articles Discussed:
- Ketamine and Magnesium for Refractory Neuropathic Pain: A Randomized, Double-blind, Crossover Trial
- Ketamine for Chronic Pain: Old Drug New Trick?
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology June 2020, Volume 132, Issue 6
Overview of June issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Mark A. Shulman, M.B., B.S., M.P.H., F.A.N.Z.C.A. and Cor J. Kalkman, M.D., Ph.D.
Articles Discussed:
Defining the Minimal Clinically Important Difference and Patient-acceptable Symptom State Score for Disability Assessment in Surgical Patients
Minimal Clinically Important Difference, Maximum Impact
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Martin Dres, M.D., Ph.D.
Article Discussed:
Usefulness of Parasternal Intercostal Muscle Ultrasound during Weaning from Mechanical Ventilation
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology May 2020, Volume 132, Issue 5
Overview of May issue original studies.
Transcript
Moderator:James Rathmell, M.D.
Participants: Yuguang Huang, M.D., Ph.D., and Yandong Jiang, M.D., Ph.D.
Articles Discussed:
Perioperative Management of Patients Infected with the Novel Coronavirus: Recommendation from the Joint Task Force of the Chinese Society of Anesthesiology and Chinese Association of Anesthesiologists
Novel Coronavirus 2019 and Anesthesiology
Transcript
This podcast relates additionally to a special article series on the Coronavirus (COVID-19) pandemic. See the full collection.
Moderator: James P. Rathmell, M.D.
Participants: Martine J. M. Breteler, M.Sc. and Bernd Saugel, M.D
Articles Discussed:
Vital Signs Monitoring with Wearable Sensors in High-risk Surgical Patients: A Clinical Validation Study
Automated Continuous Noninvasive Ward Monitoring: Validation of Measurement Systems Is the Real Challenge
Transcript
Moderator: James P. Rathmell, M.D.
Participants: John R. Greenland, M.D., Ph.D
Articles Discussed:
- COVID-19 Infection: Implications for Perioperative and Critical Care Physicians
Transcript
This podcast relates additionally to a special article series on the Coronavirus (COVID-19) pandemic. See the full collection.
Moderator: BobbieJean Sweitzer, M.D.
Participant: Karim S. Ladha, M.D., M.Sc.
Article Discussed:
Cannabis Use Disorder and Perioperative Outcomes in Major Elective Surgeries: A Retrospective Cohort Analysis
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology April 2020, Volume 132, Issue 4
Overview of April issue original studies.
Transcript
Moderator: James Rathmell, M.D.
Participants: Kamal Maheshwari, M.D., M.P.H., and editorialist David A. Story, M.D., F.A.N.Z.C.A.
Articles Discussed:
Saline versus Lactated Ringer’s Solution: The Saline or Lactated Ringer’s (SOLAR) Trial
Intravenous Fluids: Which Recipe?
Transcript
Moderator: James Rathmell, M.D.
Participants: David B. Waisel, M.D.
Article Discussed:
Compassionate and Clinical Behavior of Residents in a Simulated Informed Consent Encounter
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Michael R. Mathis, M.D. and Louise Y. Sun, M.D., S.M., F.R.C.P.C., F.A.H.A.
Articles Discussed:
- Preoperative Risk and the Association between Hypotension and Postoperative Acute Kidney Injury
- Preoperative Risk, Blood Pressure, and Acute Kidney Injury
Transcript
Moderator: James Rathmell, M.D.
Participants: Alexandre Joosten, M.D., Ph.D. and Thomas M. Hemmerling, M.D., D.E.A.A.
Articles Discussed:
- Anesthetic Management Using Multiple Closed-loop Systems and Delayed Neurocognitive Recovery: A Randomized Controlled Trial
- Robots Will Perform Anesthesia in the Near Future
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology March 2020, Volume 132, Issue 3
Overview of March issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Dan Longrois, M.D., Ph.D.
Article Discussed:
- Timing of β-Blocker Reintroduction and the Occurrence of Postoperative Atrial Fibrillation after Cardiac Surgery: A Prospective Cohort Study
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology January 2020, Volume 132, Issue 2
Overview of February issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Daniel I. McIsaac, M.D., M.P.H. and Eric C. Sun, M.D., Ph.D
Articles Discussed:
- Peripheral Nerve Blocks for Ambulatory Shoulder Surgery: A Population-based Cohort Study of Outcomes and Resource Utilization
- Regional Anesthesia: A Silver Bullet, Red Herring, or Neither?
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Michel M. R. F. Struys, M.D., Ph.D. and Jamie W. Sleigh, M.D.
Articles Discussed:
- Population Pharmacodynamics of Propofol and Sevoflurane in Healthy Volunteers Using a Clinical Score and the Patient State Index: A Crossover Study
- The Art of General Anesthesia: Juggling in a Multidimensional Space
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology January 2020, Volume 132, Issue 1
Overview of January issue original studies.
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Åse Lodenius, M.D., Ph.D., D.E.S.A. and Denham S. Ward, M.D., Ph.D.;
Articles Discussed:
- Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study
- Dexmedetomidine and the Upper Airway: Not as Simple as We Hoped
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Abraham Sonny, M.D. and Evan D. Kharasch, M.D., Ph.D.;
Articles Discussed:
- Deficit Accumulation and Phenotype Assessments of Frailty Both Poorly Predict Duration of Hospitalization and Serious Complications after Noncardiac Surgery
- Innovation in Clinical Research Regulation
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology December 2019, Volume 131, Issue 6
Overview of December issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Maud A. S. Weerink, M.D.
Articles Discussed:
- Pharmacodynamic Interaction of Remifentanil and Dexmedetomidine on Depth of Sedation and Tolerance of Laryngoscopy
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology November 2019, Volume 131, Issue 5
Overview of November issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Erland Östberg, M.D., and Karen B. Domino, M.D., M.P.H.
Articles Discussed:
- Positive End-expiratory Pressure and Postoperative Atelectasis: A Randomized Controlled Triale
- Pre-emergence Oxygenation and Postoperative Atelectasis
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology October 2019, Volume 131, Issue 4
Overview of October issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Lori A. Daiello, Pharm.D., Sc.M., and Jeffrey N. Browndyke, Ph.D.
Articles Discussed:
- Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence
- The Devil Is in the Details: Comparison of Postoperative Delirium and Neurocognitive Dysfunction
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Brandon M. Togioka, M.D.
Article Discussed:
- Education Program Regarding Labor Epidurals Increases Utilization by Hispanic Medicaid Beneficiaries: A Randomized Controlled Trial
Moderator: James P. Rathmell, M.D.
Participants: Albert Dahan, M.D., Ph.D. and Jaideep J. Pandit, M.A., B.M.B.Ch, D.Phil, F.R.C.A., D.M.
Articles Discussed:
- Reversal of a Partial Neuromuscular Block and the Ventilatory Response to Hypoxia: A Randomized Controlled Trial in Healthy Volunteers
- Reversing Neuromuscular Blockade: Not Just the Diaphragm, but Carotid Body Function Too
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Laurent G. Glance, M.D. and Jill M. Mhyre, M.D.
Articles Discussed:
- Measuring Childbirth Outcomes Using Administrative and Birth Certificate Data
- Measuring What Matters to Moms Most
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology September 2019, Volume 131, Issue 3
Overview of September issue original studies.
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Leonard U. Edokpolo, M.D.
Article Discussed:
- Discharge Readiness after Propofol with or without Dexmedetomidine for Colonoscopy: A Randomized Controlled Trial
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D..
Anesthesiology August 2019, Volume 131, Issue 2
Overview of August issue original studies.
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Adrian W. Gelb, M.B.Ch.B. and Phillip E. Vlisides, M.D.
Articles Discussed:
- Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas
- Pharmacologic Unmasking of Neurologic Deficits: A Stress Test for the Brain
Transcript
Moderator: James P. Rathmell, M.D.
Participants: Phillip E. Vlisides, M.D. and Jamie W. Sleigh, M.D.
Articles Discussed:
- Dynamic Cortical Connectivity during General Anesthesia in Healthy Volunteers
- Syncopated Tempi of the Anesthetized Brain
Transcript
Moderator: BobbieJean Sweitzer, M.D.
Participants: Domenico Luca Grieco, M.D.
Articles Discussed:
- Airway Closure during Surgical Pneumoperitoneum in Obese Patients
Transcript
Creator: Evan D. Kharasch, M.D., Ph.D.
Anesthesiology July 2019, Volume 131, Issue 1
Overview of July issue original studies.
Transcript