The Daily Stoic: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday--------- Marcus Aurelius didn’t always make the right choices. Neither will we. The important thing is what we do after we come to this realization, after we realize we’ve put something off for too long.

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Get more notes at https://podcastnotes.org Podcast Notes Premium Collection: Huberman and Sleep

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Intro to Sleep

Sleep cycles & Architecture: non-REM and REM play for brain domination throughout the night in 90-minute cycles – this is the standard architecture of sleep
Ratio of non-REM and REM throughout the night: the first half of the night is dominated by non-REM deep sleep; the second half of our sleep is dominated by REM sleep
Not everyone’s sleep cycles are 90 minutes: sleep architecture is fairly consistent within a person, but can be different across people
Non-REM Sleep: Non-REM deep sleep is divided into four stages, increasing in the depth of sleep: stages 1 and 2 are light stages of non-REM deep sleep; stages 3 and 4 are deep stages of non-REM deep sleep
In stages 1 and 2: the heart rate begins to drop, and brain wave activity slows down
In stages 3 and 4: the heart rate is low, cells in the cortex fire together then go silent
During non-REM deep sleep, we get autonomic restoration and regulation of heart rate and blood pressure
Hypnogogic Jerks: during stage 1 you experience mini dreams s you’re starting to drift off and can almost wake yourself up in this stage – sometimes you experience a jerk in your body as a result of loss of proprioceptive feedback
Don’t miss these notes about how Salvador Dali used the hypnogogic state to be creative (Slumber with a Key)
…

Quantity, Quality, Regularity, and Timing (QQRT): The macros of sleep

Quantity: the average adult needs between 7-9 hours of sleep per night – but the reality is more complex
Quantity alone doesn’t tell the full story
…

Carbs, Caffeine and THC

Carbs in AM vs. PM: research does seem to support that your body is better able to metabolize carbohydrates in the morning versus evening if you’re concerned about your blood sugar and metabolic health
Eating Before Bed: In gener…

Sleep Supplements

Magnesium Threonate or Glycinate, 145mg, 30-60 minutes before sleep
Magnesium chloride can be effective for bioavailability by way of muscle relaxation
Apigenin: 50mg, 30-60 minutes before sleep
Theanine: 100-400mg, 30-60 minutes before sleep (Do NOT take Theanine if you are prone to night terrors or sleepwalking)
Inositol
Glycine: 1.5-2gPhosphatidylserine will dampen cortisol response
Check out the full Momentous Huberman sleep stack & use promo code PODCASTNOTES for 15% off at checkout!

Sleep Tips

1. Do Nothing! If you are struggling with sleep and had a bad night of sleep, do not sleep in later, do not go to bed earlier, do not increase caffeine intake, do not compensate with a nap
2. Time rescheduling/sleep restriction therapy: if you are spending too much time in bed, your brain is not efficient; it’s like being in the gym for hours a day but spending most of the time scrolling on your phone – you’re not really getting a good workout like if you know you only have 45 minutes to workout
3. Don’t underestimate the importance of a winddown routine: whatever you enjoy for relaxation, build it into your regimen to help you decelerate
4. Do NOT count sheep, instead take yourself on a mental walk: counting sheep actually makes you stay awake longer; instead, get your mind off itself by going through a rudimentary walk with hyper-detail – imagine putting your shoes on, opening the door, crossing the street, imagine the signs you see, look at the flowers, etc.
5. Remove …
Monophasic sleep: Single bout of sleep in 24 hour period
Biphasic sleep: Two bouts of sleep in 24 hour period
Polyphasic sleep: …

Napping

Naps are a Double-Edged Sword: If you struggle with sleep at night, do not nap during the day in order to build up sleepiness and hopefully sleep at night
Cons of Napping: Naps remove sleep pressure (adenosine) so if you struggle with sleep, you are setting yourself up for worse sleep because you’ve removed some of the sleepiness you need
Pros of Napping: If napping does not disrupt your sleep and leaves you feeling better, go ahead and nap but be cautious of napping too late which can disrupt sleep
Are Naps Right F…
Super Charged Nap: Swig espresso right before napping + nap 20 minutes + cold water to hands and face upon waking + immediate daylight 5-10 minutes outside

3 Ways Sleep is Essential for Learning:

1: We need sleep before learning to start the initial imprint and laying the tracks; sleep before learning is critical
2: We also need sleep after learning to cement the information in our brain
3: We need sleep to integrate the new information with previously learned information we have stored
Exactly How Much an All-Nighter Impacts Memory: Pulling an all-nighter leads to deficits of up to 40% in making new memories
…
Symptoms of REM Sleep Deprivation: Paranoia, hallucination, aspects of psychosis (with enough time)
Bad Sleep, And Then: When sleep deprived, you’re excessively reactive and hypersensitive, particularly to reward-based activities – dopamine circuits are overactive when you are underslept
Sleep and Addiction: A lack of sleep is associated with addiction potential AND relapse if trying to abstain
REM Sleep Killers: Alcohol, THC
One Possible Mechanism for PTSD: The brain is trying to process the traumatic experience but fails, so the brain tries again the next night, and the next – until …

Brain Features of REM:

(1) Electrical brain wave activity in the cortex is similar to that when you are awake;
(2) There are unique pulses from the brain stem ultimately to the occipital cortex (linked to rapid eye movements);
(3) Motor regions, visual regions, memory-related structures, and emotional-related structures of the brain all light up
(4) The dorsolateral prefrontal cortex (responsible for inhibition and planning) activity is suppressed during REM
Functions of REM sleep: (1) Creativity; (2) Emotional & mental wellness – REM sleep is overnight therapy
…
(1) Consistently rehearse the notion that you will remember your dreams and you will take control of your dreams – if you do this enough, the probability you will induce lucid dreams is high
(2) Rehearse something (like flicking a light switch on and off) over and over; Then, when this appears in your dream you can take control
…

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Invest Like the Best: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------My guest today is Jared Kushner. Jared has lived more lives than just about anyone I know his age. He ran Kushner companies for years, investing in real estate in and around New York City. He owned the New York Observer. He was a senior advisor to President Trump in his first term. He now runs Affinity Partners, which we discuss in detail, a private equity firm built to find and execute unique investments around the world that stem from Jared's unique set of experiences in business and government. This is one of our longest episodes ever because there was so much to discuss. We cover real estate, negotiation, geopolitics, his work in prison reform, Operation Warp Speed, and the Abraham Accords in the Middle East, business, investing, his family, and everything in between. Jared told me I could ask him about anything--and I really enjoyed doing so. Please enjoy my conversation with Jared Kushner.My guests today For the full show notes, transcript, and links to mentioned content, check out the episode page here.-----This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. AlphaSense provides access to over 300 million premium documents, including company filings, earnings reports, press releases, and more from public and private companies. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster.–-This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.–-This episode is brought to you by Ramp. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Ramp is the fastest growing FinTech company in history and it’s backed by more of my favorite past guests (at least 16 of them!) than probably any other company I’m aware of. Go to Ramp.com/invest to sign up for free and get a $250 welcome bonus.-----Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).Show Notes:(00:00:00) Welcome to Invest Like the Best(00:08:45) Jared's Philosophy on Challenges and Success(00:13:38) Real Estate Ventures: The 666 Fifth Avenue Story(00:20:31) Lessons from New York Real Estate(00:30:04) Diplomacy and the Middle East(00:37:03) Leadership and Change(00:41:14) Geopolitical Landscape and Future Prospects(00:47:53) Affinity Partners: Vision and Strategy(00:52:42) Navigating Market Shifts(00:54:39) Case Study: Mexico Investment(00:58:34) Global Investment Strategies(01:02:42) Investment Philosophy and Principles(01:07:04) Challenges and Problem-Solving(01:23:14) Government Efficiency and Bureaucracy(01:34:57) Stepping into the Spotlight(01:37:19) Manifesting Success with Partners(01:38:05) Learning from Brad Jacobs(01:42:09) Middle East Economic Development(01:46:08) The Qatar-Saudi Reconciliation(01:52:25) Perceptions of Key Middle Eastern Countries(02:07:34) Preparing for Trump's Return(02:14:36) Early Days of Thrive Capital(02:16:56) Helping Entrepreneurs and Building Thrive(02:24:51) Lessons from My Father(02:37:47) Future Vision and AI(02:48:45) The Kindest Thing Anyone Has Ever Done For Jared

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Philosophize This!: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday---------Today we talk about the philosophical themes of one of Dostoevsky's most famous books: Notes From Underground. We talk about contemplative inertia, the "stone wall" of rationality, utopian socialism, the tension between love and freedom in the modern world, self-loathing as a defense mechanism, and much more. Hope you enjoy it. :)Sponsors:Nord VPN: https://nordvpn.com/philothis Aura Frames: https://www.AuraFrames.com use promo code: PTBetter Help: https://www.BetterHelp.com/PHILTHISThank you so much for listening! Could never do this without your help. Website: https://www.philosophizethis.org/Patreon: https://www.patreon.com/philosophizethis Social:Instagram: https://www.instagram.com/philosophizethispodcastX: https://twitter.com/iamstephenwestFacebook: https://www.facebook.com/philosophizethisshow

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5 Ways Stem Cells Will TRANSFORM What It Means To Be Healthy | The Gabby Reece Show

Christian Drapeau (@stemcellchristian) is a pioneer in stem cell research. And the first to propose stem cells as the body’s innate repair system. Christian Drapeau discusses the transformative potential of stem cells in health and healing. They explore the basics of stem cells, their role in the body, the evolution of stem cell research, and the impact of aging on stem cell efficacy.

The Roman Caesars’ Guide to Ruling | Barry Strauss on The Art of Manliness with Brett McKay (#1047)

How often do you think about the Roman Empire? Lately, this question has gone viral, leaving many women wondering why their husband or boyfriend is reflecting on Roman history so often. The truth lies in the Empire’s enduring allure: its epic tales of power, war, ambition, innovation, and dramatic leadership. In these Premium Podcast Notes, we turn to historian Barry Strauss who gives a detailed overview of his book, Ten Caesars: Roman Emperors from Augustus to Constantine, unpacking the themes that make Rome’s legacy a timeless source of fascination.

Podcast Notes Book Collection: 2024 Edition (UPDATED AND COMPLETE with 200+ Books)

After reviewing all 400+ Podcast Notes we wrote in 2024, we selected a comprehensive reading list of over 200 books. Whether you’re a new parent, hopeful entrepreneur, tech geek, history buff, or just a general bookworm, there’s truly something for everyone!

Top Takeaways Of The Week

5 Ways Stem Cells Will TRANSFORM What It Means To Be Healthy | The Gabby Reece Show 

Stem Cells With Age: By age 30, you’ve lost 90% of red marrow stem cells; as stem cells disappear from the body, the loss becomes increasingly apparent over time

Stem cell sources: Bone marrow, fat tissue, blood, umbilical cord

Yamanaka factor: Take old cells and turn them into cells with characteristics of young cells

Why We Lose Them: “Over the past 150 years, we’ve gained an extra 50 years of lifespan. I don’t think we have the biology to have an extra 50 years naturally with full blossoming health. We need to kind of hack and tap and leverage things in our body.” – Christian Drapeau

Stem cells from blood (like PRP) are very potent; they’re dormant so need to be ‘awakened’. This is likely the future of stem cells and relatively new to use; the task now is to learn how to isolate and grow them for use Stem cells from the umbilical cord: The most potent – but not as mainstream because of three notable concerns:

(1) Risk of contaminated stem cells is high which can lead to sepsis;
(2) They’re difficult to isolate cleanly;
(3) You can obtain genetic material from a donor who may have been a carrier for a disease that you may develop in the future

Tips to Supported Stem Cells:

Red lights might help with bodily repair, possibly by aiding blood circulation
Pulsed magnetic frequency (PMF) has been well-documents to boost stem cell frequency
Exercise releases stem cells – but this might be because if you trigger tissue damage, your body will trigger a response
Quality sleep supports the proliferation of brain stem cells
Meditation has a healing component – 20 minutes of meditation has been shown to encourage stem cell release
Plants for health: Shilajit, black seed (periodically), natto, kava (hard to source)

The Roman Caesars’ Guide to Ruling | Barry Strauss on The Art of Manliness with Brett McKay (#1047) 

The Rise of Octavian/Augustus Caesar: Octavian, born Gaius Octavius, was Julius Caesar’s grand-nephew and was adopted posthumously as part of Caesar’s will — which was technically illegal, but law was pretty loose during civil war

How to Win the Game of Thrones: Augustus simply killed off a lot of his enemies, between several civil wars and the execution of about 100 Roman senators

Augustus' Expansion: Octavian added Egypt, northwestern Spain, and Switzerland to the Roman Empire

The Infamy of Nero: Nero was less interested in the empire itself and more interested in the celebrity of being Emperor

He was egotistical and also very vain about his singing and chariot racing ability
He competed in the Panhellenic Games and “won” every event

The Truth About Nero's Fiddling While Rome Burned: There’s a rumor that Nero fiddled while Rome burned, but the fiddle technically hadn’t been invented yet. However, he may have played a lyre, which is a harp-like instrument.

There are even rumors that claim Nero started the fire, with the intent to engage in a massive urban renewal project

Marcus Aurelius, the Ivory Tower Emperor: Marcus Aurelius was a great philosopher but not a great emperor

Marcus Aurelius had no military experience or experience outside Italy, he was completely unprepared to become empowered — a common theme in the Roman Empire system
He let is son Commodus follow him as emperor

Commodus, The Villain: The first man born to be emperor

Commodus was arrogant, entitled, and irresponsible
Competed as a gladiator
He offered bread and circuses to the people but killed many senators
Eventually, the senate carries out a plot to kill Commodus

Dr. Laurie Santos: HowTo Achieve True Happiness Using Science-Based Protocols | Huberman Lab

Happiness Operates on 3 Timescales: (1) The immediate timescale of happiness; (2) The intermediate timescale of happiness where we introduce a story; (3) Meaning which is the full picture

Tips to Approach Happiness on All 3 Levels:

Engage in activities that fit with values and strengths;
Infuse strengths into work & leisure;
Do for others
Ask others for help

Extrinsic rewards: A tangible, visible reward for achieving something

Intrinsic rewards: Reward comes from within, feeling progress, purpose, etc.

On the lower end of the income spectrum, money affects happiness: If you struggle to put food on the table, keep a roof over your head – more money almost has a linear relationship with happiness

Stop being a Sad Loner: One of the biggest levers you can pull to improve happiness is to get more social connection“The two things that predict whether you’re happy or not so happy are how much time you spend with friends and family members and how much you are physical around other people. The more of that you do, the happier you’re going to be.” – Laurie Santos

Dopamine Must Be Earned, Not Given: “Be wary of any dopamine hit not preceded by effort to achieve it.” – Andrew Huberman

Prediction error: Introverts predict social connection will be negative, when in actuality they get report a great experience; extroverts predict social connection will be ok, and anticipation is high

Negativity bias: We’re built to notice the risky, potentially scary stuff; our brain goes there automatically which makes sense evolutionarily

Toxic Positivity: The notion that something is wrong if you’re feeling anything but happy or ‘good vibes’; negative emotions are a cue from our body to take action in some direction to fix

Dog vs. Cat People: If you crave unconditional love, you are probably more of a dog person; cats are more independent

Hedonic adaptation: We get used to things; you can’t be happy all the time because you become sensitized

“Every good thing in life becomes boring after some time.” – Laurie Santos
Tip: Imagine the negative things and obstacles; use worse things as a comparison to realize how good things are – don’t ruminate on it but use your imagination to appreciate what you have
Tip #2: Space out positive experiences to come back to them over time

Banister effect: Believe something is positive; be optimistic enough to think something is doable then ask yourself the question ‘what will get in the way?’ so you problem-solve

Arrival fallacy: The idea, “I’ll be happy when…” – the thing we arrive at doesn’t feel as good once we get there and we chase the next thing

Micky Malka – Building Ribbit | Invest Like the Best with Patrick O’Shaughnessy Ep. 400

Life and business principles from Micky Malka:

1. Never forget where you came from
2. Fewer decisions is best
3. Be genuine to yourself and those around you

Lessons learned from the Robinhood saga

Being the CEO is a very lonely existence
Develop and craft a flexible mindset so that you can be comfortable taking risk
When you truly understand the variables at play, you will be more comfortable with taking ‘risk’
Mistakes made in a single day can damage a company’s brand for years to come

Technologies have their own grid complexes

The electrical grid consists of towers, power meters, transformers, and more
The internet is a grid of data and knowledge
The monetary system has its own grid as well, consisting of the different financial layers and rails which include Visa, Mastercard, SWIFT, etc

Stablecoins: US dollar stablecoins are travel checks in today’s world; they are instant dollars that the individual can control and move, anytime, and for zero

Stablecoins provided people with access to US dollars who previously did not have access to dollars and who were forced to use their local (and weaker) fiat currency
Today, US-dollar stablecoins do a similar monthly volume to that of Visa and Mastercard

What Got You Here, Won't Get You There: Burn the bridge that got you here; whatever got you here will not get you to the next phase

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Honestly with Bari Weiss ✓ Claim

Key Takeaways * Prominent people are shifting to the right because they never signed up for the left’s intellectual straight-jacket * The 2024 presidential election marked a collapse of liberalism and the Democratic Party; it is too narrow of thinking to blame it on a senile Biden or a goofy Kamala * If the machine always wins, then you no longer have a democracy nor a democratic process: If Trump would have lost to the machine in 2024, who would have ever been able to defeat it? * If we are going to avoid World War III, we must learn the lessons of WWI and WWII; we cannot have excessive appeasement to dictators, but also, we cannot sleepwalk into armageddon * On the elite Ivy League institutions: “Maybe they’re good places for training conservatives. If you go to Yale Law School and you’re one of five people in the class who are still conservative at the end, you’ll be pretty good at understanding what’s wrong with liberalism.” * Populism and democracy may be a Russell conjugate: It is democracy when people vote the right way and it is populism when they vote the wrong way * Both extreme dogmatism and extreme skepticism are incompatible with science * If you make something into God, you make it into a scapegoat for all the problems too * If you’re addicted to the 140 characters on your shiny iPhone screen, you may not realize that the New York Subway and your decrepit apartment building are collapsing around you * It matters what people do; there is room for human agency and human thought in the trajectory of the future

Read the full notes @ podcastnotes.org

On Tuesday night, president-elect Donald Trump announced that the richest man in the world, Elon Musk, along with entrepreneur Vivek Ramaswamy will head a new department in the Trump administration: the Department of Government Efficiency, or “DOGE.”

Aside from the very strange fact that internet meme culture has now landed in the White House—Dogecoin is a memecoin—more importantly, what the announcement solidifies is the triumph of the counter-elite. A bunch of oddball outsiders ran against an insular band of out-of-touch elites supported by every celebrity in Hollywood—and they won. And they are about to reshape not just the government but also the culture in ways we can’t imagine.

And there was one person I wanted to discuss it with. He is the vanguard of those antiestablishment counter-elites: Peter Thiel. People describe the billionaire venture capitalist in very colorful terms. He’s been called the most successful tech investor in the world. A political kingmaker. The bogeyman of the left. The center of gravity in Silicon Valley. There’s the “Thielverse,” “Thielbucks,” and “Thielists.” To say he has an obsessive cult following would be an understatement.

If you listened to my last conversation with Thiel a year and a half ago on Honestly, you’ll remember that Peter was the first guy in Silicon Valley to publicly embrace Trump in 2016. That year, he gave a memorable speech at the RNC, and many in his orbit thought it was simply a step too far. He lost business at Y Combinator, the start-up incubator where he was a partner. Many prominent tech leaders criticized him publicly, like VC and Twitter investor Chris Sacca, who called Thiel’s endorsement of Trump “one of the most dangerous things” he had ever seen.

Well, a lot has changed since then. For one, Thiel has taken a step back from politics—at least publicly. He didn’t donate to Trump’s 2024 campaign. There was no big RNC speech this year. But the bigger change is a cultural one. He’s no longer the pariah of Silicon Valley for supporting Trump.

On the surface, Thiel is someone who seems full of contradictions. He is a libertarian who has found common cause with nationalists and populists. He likes investing in companies that have the ability to become monopolies, and yet Trump’s White House wants to break up Big Tech. He is a gay American immigrant, but he hates identity politics and the culture wars. He pays people to drop out of college, but, in this conversation at least, still seems to venerate the way that the Ivy Leagues are an indicator of intelligence.

But perhaps that’s the secret to his success: He’s beholden to no tribe but himself, no ideology but his own. And why wouldn’t you be when you make so many winning bets? From co-founding the e-payment behemoth PayPal and the data analytics firm Palantir (which was used to find Osama bin Laden) to being the first outside investor in Facebook, Thiel’s investments—in companies like LinkedIn, Palantir, and SpaceX, to name a few—have paid off big time.

His most recent bet—helping his mentee J.D. Vance get elected as senator and then on the Trump ticket as vice president—seems also to have paid off. The next four years will determine just how high Thiel’s profit margin will be.

Today: Thiel explains why so many of his peers have finally come around to Trump; why he thinks Kamala—and liberalism more broadly—lost the election; and why the Trump 2.0 team will be better than last time, with antiestablishment figures who are willing to rethink the system. We talk about the border, trade deals, student debt, Israel and foreign policy, the rise of historical revisionism, the blurry line between skepticism and conspiracy, and his contrarian ideas about what we might face in a dreaded World War III.

If you liked what you heard from Honestly, the best way to support us is to go to TheFP.com and become a Free Press subscriber today.
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Ben Greenfield Fitness

Key Takeaways * Carbon dioxide serves as the body’s signal to take the next breath, not oxygen * Oxygen and carbon dioxide are like yin and yang: pH drops when CO2 goes up – when pH goes down, there’s more oxygen delivered via hemoglobin into mitochondria + The goal is to reduce respiratory rate so you can become more efficient * You can use different breathwork timing to manipulate your state: Inhale is tied to activation; exhale is for relaxation + Use a longer exhale to relax + Fast breathing is the hallmark of stress and hyperventilation * CO2 therapies (like blood flow restriction) can also be used to increase muscle size by trapping more CO2 in working muscles * Cautions: When starting CO2 training start slow and listen to your body! Don’t be discouraged if you don’t notice improvements quickly, it can take some time to find the right dose for your body

Read the full notes @ podcastnotes.org

Carbon dioxide therapy has become a highly debated and often misunderstood topic.

Is elevated CO2 beneficial, or could it pose risks? What exactly are the advantages of CO2 therapy, and how might it impact your health?

In this episode, you’ll get to explore the transformative power of breathing with breathwork expert Anders Olsson. From the benefits of food-grade CO2 cylinders to advanced breathing techniques that can boost both mental and physical well-being, Anders shares invaluable insights. As the author of Conscious Breathing: Discover The Power Of Your Breath and creator of tools like the Relaxator and CarboHaler, he guides you through the profound impact breathwork has on emotions and stress management. You’ll uncover the fascinating relationship between CO2 and oxygen delivery, the role of nitric oxide in respiratory health, and how specific breathing patterns can dramatically reduce stress and elevate overall health. Plus, you’ll gain practical advice and discover cutting-edge research to enhance your daily breathwork practice.

Anders Olsson is a breath coach, author, keynote speaker, inventor, and founder of the Conscious Breathing Institute. Anders joins me on the podcast to bring clarity to the benefits, potential concerns, and safe applications of CO₂ therapy. After living most of his life with a high inner stress and a racing mind, Anders was fortunate enough to come across tools that have helped him relax and find his inner calm. The most powerful of these tools has undoubtedly been to change his breathing habits, which made Anders decide to become the world’s most prominent expert in breathing.

That was 15 years ago, and since then, he has inspired hundreds of thousands of people to achieve better health and an improved quality of life. Anders is the author of the best-selling book Conscious Breathing: Discover The Power of Your Breath and the co-inventor of the Relaxator, Sleep Tape, CarboHaler, and BodyStream CO2 Bath.

He is considered an authority on CO2 therapy and coaches high-level executives and elite athletes. In 2018, Anders facilitated and participated in a groundbreaking three-week breathing study at Stanford, highlighted in James Nestor's book Breath.

Tune in and breathe easy as we unpack the science and art of effective breathing to help you reduce stress, boost energy, and enhance your overall well-being.

Full show notes: BenGreenfieldLife.com/CO2podcast

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All-In with Chamath, Jason, Sacks & Friedberg

Key Takeaways * The Trump win represents a dismissal of Wokeism and judgmentalism and is a ringing endorsement of meritocracy and common sense * Donald Trump has increased his support across the electorate; except for two demographic groups (65+ and white college women), every single demographic group shifted towards Republican from 2020 to 2024 * Comparing Trump votes from 2020 to 2024 in areas that are bastions of elitist liberal thinking: + In California, Trump lost by 29 points in 2020; he lost by 17 points in 2024 + In New York, Trump lost by 23 points in 2020; he lost by 12 in 2024 * The current Democratic Party base consists of the elites: The overeducated, affluent, and non-religious types who are disconnected from the reality of most Americans + If these people stay in control of the Democratic Party, the Republicans will probably have an electoral majority for the foreseeable future + “I think that the Democrats will lose one of California or New York in the next eight years.” – Chamath * “The legacy media spell is broken. Their credibility has been destroyed and I think that the repudiation of the legacy media is one of the most important results of this election. It just shows that the Democrats had a trillion-dollar propaganda machine on their side and Trump was still able to win.” – David Sacks * Science is the constant process of questioning whether you are right or wrong; reasserting the scientific process of skepticism in federal agencies may help restore trust and faith in our institutions * “In the most basic calculation, the bottom fell out of the Democratic Party.” – Chamath * Donald Trump won because his focus is on solving real problems that are affecting Americans * “Americans love winners and innovation, and they hate socialism and woke nonsense – it’s time for a hard reset.” – Jason

Read the full notes @ podcastnotes.org

(0:00) Bestie intros!

(4:55) Sacks recaps election night at Mar-a-Lago

(8:28) Analyzing the results: how Trump won, why Kamala and the Democratic Party lost

(25:55) The failing Democratic coalition, campaign spend disparity, Trump's advantage in earned media

(37:59) What mattered most: Policy, Candidate, or Campaign?

(50:44) GOP will likely win House and Senate, potential cabinet positions, avoiding neocons

(1:10:42) Cabinet positions, shaking up the unelected bureaucratic branch

(1:28:47) California rejects progressives

(1:35:17) Abortion laws being settled around the US

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Referenced in the show:

https://x.com/twobitidiot/status/1854192602985255042

https://www.270towin.com/2024-election-results-live/president

https://x.com/ChrisCillizza/status/1854515791690953066

https://www.youtube.com/watch?v=_e8-KX3XKL8

https://x.com/Jason/status/1854209590424121464

https://x.com/SawyerMerritt/status/1854045298475110779

https://x.com/DavidSacks/status/1854342908356297068

https://x.com/arifleischer/status/1854270972775305291

https://www.fec.gov/data/spending-bythenumbers/?office=P

https://www.usnews.com/news/national-news/articles/2024-11-01/16-billion-will-be-spent-in-the-2024-election-wheres-it-all-going

https://x.com/DavidSacks/status/1829383729284067659

https://www.snopes.com/fact-check/trump-very-fine-people

https://x.com/TheRabbitHole84/status/1840977783247286429

https://www.cnn.com/election/2024

https://polymarket.com/event/house-control-after-2024-election

https://x.com/MarioNawfal/status/1854536321282519396

https://www.instagram.com/p/DCFJ4mlsmEG/?hl=en

https://x.com/DavidSacks/status/1854202717637411199

https://www.scotusblog.com/2024/06/supreme-court-strikes-down-chevron-curtailing-power-of-federal-agencies

https://x.com/chamath/status/1854229735477551600

https://www.nbcnews.com/politics/2024-election/la-district-attorney-progressive-loses-re-election-gascon-rcna175906

https://www.nytimes.com/interactive/2024/11/05/us/elections/results-abortion.html

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Pomp Podcast

Key Takeaways * The fundamental aspect of the American Dream is creating a better life for your kids than the one you lived * Two-thirds of the American workforce has a high school education, and only one-third has a college education; on average, a person with a college education lives seven years longer than a person without one * “Right now, I am focused on: ‘What’s the right move for America?’ And that’s why I’m all in with Donald Trump – his policies, his thinking, his way of just looking at things, his intuition. It’s just right.” – Howard Lutnick * In the past, the Democratic Party used to be the party for the workers, and the Republican Party was the party for businesses, but this has completely shifted + Coastal elite nonsense has infiltrated the Democratic Party; it no longer represents the working class as it once did * Instead of taxing the hell out of the American people, what if the US government made money off tariffs when other countries bought our stuff? * All of the fentanyl that makes its way into the US comes from China; something nefarious might be at play, given the damage this drug is doing to America’s youth and working-class * After the 9/11 attacks, Howard Lutnick pledged to forgo his salary and bonuses for several years to support the families of Cantor Fitzgerald employees who lost their lives * “Everytime bitcoin dips, I’m going to be the buyer.” – Howard Lutnick + He has “hundreds and hundreds of millions of dollars” worth of exposure to Bitcoin, and one day expects his stack to be worth billions * “Bitcoin will be way way way higher, sometimes lower. You just have to have faith.” – Howard Lutnick

Read the full notes @ podcastnotes.org

Howard Lutnick is the CEO of Cantor Fitzgerald. Howard is one of the most interesting people in finance, he is a billionaire, and has incredible ideas to improve America. In this conversation, we talk about the national debt, inflation, why he is the co-head of the Trump transition team, what their plan is to balance the budget, how they are going to change things around economically, and a touching story about 9/11.

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Pomp writes a daily letter to over 265,000+ investors about business, technology, and finance. He breaks down complex topics into easy-to-understand language while sharing opinions on various aspects of each industry. You can subscribe at https://pomp.substack.com/

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My First Million

Key Takeaways * Paradoxically, life gets easier when you choose to do hard things * Have a goal that you can strive towards, but be cognizant of how you feel along the way in pursuit of that goal * One of the hardest things in life is figuring out what you want * “I think everybody should get rich and famous and do everything they ever dreamed of so they can see that it’s not the answer.” – Jim Carey * You have emotional sovereignty in how you choose to react to everything that happens in life; exercise and develop that sovereignty so that you can live the fullest life possible * How Cheap is Your Happiness: Don’t let the smallest inconvenience take you out of the beautiful state of being that is happiness * “I just do what’s cool to me, and sometimes the whole world agrees.” – Mike Posner

Read the full notes @ podcastnotes.org

Episode 640: Shaan Puri ( https://x.com/ShaanVP )sits down with Mike Posner ( https://x.com/MikePosner ) about his insane hustle, fame, loss and reinvention.
—
Show Notes:
(0:00) iTunesU Story
(14:41) Going back to school, famous
(21:40) Getting on the radio
(26:40) “I just do what's cool to me and sometimes the whole world agrees”
(30:06) One true sentence / Writing Process
(39:50) Money, fame and Survivor
(46:52) Advice to my younger self
(48:10) Missed flight story
(58:00) The making of a hit song
(1:04:31) Walking Across America
(1:11:09) "How cheap is your happiness?"
(1:14:17) Beautiful States v Suffering States

—
Links:
• Mike Posner - https://mikeposner.com/

—
Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

—
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• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth
• Sam’s List - http://samslist.co/

My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

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Genius Life

Dr. Yvonne Burkart is a board-certified toxicologist with over 15 years of experience specializing in environmental health, chemical safety, and human health risk assessment.

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Impact Theory with Tom Bilyeu

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

In this thought-provoking episode of Impact Theory with Tom Bilyeu, Tom sits down with tech visionary Mark Andreessen for an insightful discussion on the evolving role of technology in shaping our future. From the promise of AI and robotics to the pivotal lessons from historical economic changes, Mark argues that today's children will live better lives than their parents, thanks to technological advancements.

Together, they delve into the implications of slow and rapid technology adoption across various sectors, highlighting how healthcare, education, and housing can benefit from embracing innovation. They explore the inefficiencies plaguing large corporations and juxtapose them with the rapid, iterative methodologies championed by leaders like Elon Musk.

Mark offers a nuanced perspective on America's unique dynamism, driven by its people and less stifled by regulation compared to Europe. He and Tom also dive into the potential societal conflicts arising from AI, the nuances of free speech in the digital age, and the ever-present need for productivity growth.

SHOWNOTES
00:00 Pre-meeting tech check with Tom planned.
31:34 Robotics' societal impact: automation and breakthroughs emerging.
39:30 Voice AI now enables engaging human-like interactions.
47:13 AI usage is widespread, impacting work and education.
57:54 Technology enhances material comfort, aids existential exploration.
01:05:27 Religion is now independent from genetics and location.

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Drive with Dr. Peter Attia

Key Takeaways * The human genome was sequenced 25 years ago, what’s the delay in editing? We know the sequence of the genes but we don’t know what most of the genes do, nor do we fully understand the coding and non-coding sequence (yet) * CRISPR is an adaptive immune system: After the first infection, the bacteria has been ‘vaccinated’ against the virus + The next time the virus comes around, it will inject its genetic information into the bacteria but now the bacteria in the CRISPR area have a signature of the virus * Difficulties in application of CRISPR: CRISPR uses a guide RNA to recognize the virus DNA but delivery of the Cas + guide RNA needs to be precise and the protein is too large to insert with ease + But, solving the delivery issue doesn’t mean CRISPR is suitable for all diseases; its most potent application is for genetic mutations (and likely not cancer which has many different mutations in the cell) * Future goals of CRISPR technology: Creating more feasible Cas and guide RNA delivery system; inserting large genes into the genome, precisely and efficiently * Ethical considerations of gene editing germline: + Slippery slope argument: If we allow X and Y, we will enter an unchartered territory with designer babies, making babies smarter (which we don’t know how to do), etc. - It’s worth noting that athletics, and intelligence, are more complicated than we want to believe; even with the right genetics, environment plays a huge role in realizing genes + Thinking about how the line should be drawn: Is there an obvious and important medical benefit?

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Feng Zhang, a professor of neuroscience at MIT and a pioneering figure in gene editing, joins Peter to discuss his groundbreaking work in CRISPR technology, as well as his early contributions to optogenetics. In this episode, they explore the origins of CRISPR and the revolutionary advancements that have transformed the field of gene editing. Feng delves into the practical applications of CRISPR for treating genetic diseases, the importance of delivery methods, and the current successes and challenges in targeting cells specific tissues such as those in the liver and eye. He also covers the ethical implications of gene editing, including the debate around germline modification, as well as reflections on Feng’s personal journey, the impact of mentorship, and the future potential of genetic medicine.

We discuss:

Feng’s background, experience in developing optogenetics, and his shift toward improving gene-editing technologies [2:45];
The discovery of CRISPR in bacterial DNA and the realization that these sequences could be harnessed for gene editing [10:45];
How the CRISPR system fights off viral infections and the role of the Cas9 enzyme and PAM sequence [21:00];
The limitations of earlier gene-editing technologies prior to CRISPR [28:15];
How CRISPR revolutionized the field of gene editing, potential applications, and ongoing challenges [36:45];
CRISPR’s potential in treating genetic diseases and the challenges of effective delivery [48:00];
How CRISPR is used to treat sickle cell anemia [53:15];
Gene editing with base editing, the role of AI in protein engineering, and challenges of delivery to the right cells [1:00:15];
How CRISPR is advancing scientific research by fast-tracking the development of transgenic mice [1:06:45];
Advantages of Cas13’s ability to direct CRISPR to cleave RNA and the advances and remaining challenges of delivery [1:11:00];
CRISPR-Cas9: therapeutic applications in the liver and the eye [1:19:45];
The ethical implications of gene editing, the debate around germline modification, regulation, and more [1:30:45];
Genetic engineering to enhance human traits: challenges, trade-offs, and ethical concerns [1:40:45];
Feng’s early life, the influence of the American education system, and the critical role teachers played in shaping his desire to explore gene-editing technology [1:46:00];
Feng’s optimism about the trajectory of science [1:58:15]; and
More.

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Modern Wisdom

Key Takeaways * Now more than ever,young men are uncertain about what the world needs from them * The increase in young male suicide may be due to men retreating from the difficulties and challenges of modern society * “The state of feeling unneeded is literally fatal.” – Richard Reeves * Four out of five teens who commit suicide are boys: Across every age group, the suicide rate is 4x higher amongst men than women * There has been an expansion in the domains of neediness for women and a contraction in the domain of neediness for men * The mental health field is more female-friendly than male-friendly; the whole field of mental health has been coded as female and feminine – and we wonder why men are not interested in it! * Young men feel politically homeless, and they especially do not feel welcomed by the political left; instead of turning to the left or the right, younger men tend to retreat * Recently, there has been a massive increase in drug poisoning deaths among young men + From 2001 to today in the United States, the increase in deaths from drug poisoning is equivalent to an additional 400,000 men * In the US, only half of men in their 30s and 40s without a college degree are in a household with children * For men, the old form of neediness as a protector has been significantly evacuated and replaced by nothing * The best protector against despair is realizing that the world needs you

Read the full notes @ podcastnotes.org

Richard Reeves is a writer, researcher and the Founder of the American Institute for Boys & Men.
Men have been struggling for a long time. What exactly is going on? What resources can genuinely help modern men, and how can we better understand the dynamics that are driving this decline in male wellbeing.
Expect to learn why Obama endorsed Richard’s book, the scary trends about male suicide, why it's important for humans to feel needed, whether the Harris-Walz campaign has even considered men's existence, if this upcoming election will be decided by masculinity, Richard’s thoughts on therapy for men and much more….
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

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700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

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Genius Life

Key Takeaways * In medicine (and everywhere), there is resistance to new ideas – so many people have spent so much time holding a certain belief, that the cost is too high to change * The distrust in science and medicine is because there is no humility in walking back incorrect information * We need people who are willing to speak up instead of falling in line; science is the study of challenging deeply held assumptions * We need new frontiers of medicine, people are hungry for answers * The future of medicine is hopeful as the new generation of medical students and doctors is not on board with the traditional path of doing whatever you need to secure NIH funding and falling in line + It’s time we consider NIH term limits + We spend more money on pharmaceuticals than we do on understanding the origins of disease * New formula for medicine: (1) Invite dissenting opinions; (2) Create a culture of speaking up; (3) Recognize that we all have biases and suspend those biases as we hear new information

Read the full notes @ podcastnotes.org

Marty Makary, MD is a Johns Hopkins professor and member of the National Academy of Medicine. He is the author of Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health.

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Founders✓Claim

Key Takeaways * “If Steve Jobs studied Edwin Land, I think every other founder should as well.” – David Senra * Optimize for breadth as well as depth; hire the chemist who does photography on the side! * Something magical exists at the intersection of the humanities and the sciences * “Missionaries make better products.” – Jeff Bezos + Missionaries and mercenaries are the two types of people that will be attracted to a company + While the mercenaries are there for the perks, status, and money, the missionaries are there to make better products because they believe in what the company is doing * Leverage the power of demonstration: No argument in the world can compare with one dramatic demonstration * A first-class product needs first-class packaging and marketing! * The founder is the guardian of the company’s soul * If you are lucky enough to find your life’s work, why would you quit? * You should take yourself seriously, but don’t make yourself miserable; none of us get out of this alive

Read the full notes @ podcastnotes.org

What I learned from rereading Instant: The Story of Polaroid by Christopher Bonanos.

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Episode Outline:

— The most obvious parallel is to Apple Computer. Both companies specialized in relentless, obsessive refinement of their technologies. Both were established close to great research universities to attract talent. Both fetishized superior, elegant, covetable product design. And both companies exploded in size and wealth under an in-house visionary-godhead-inventor-genius. At Apple, that man was Steve Jobs. At Polaroid, the genius was Edwin Land. Just as Apple stories almost all lead back to Jobs, Polaroid lore always seems to focus on Land.

— Both men were college dropouts; both became as rich as anyone could ever wish to be; and both insisted that their inventions would change the fundamental nature of human interaction.

— Jobs expressed his deep admiration for Edwin Land. He called him a national treasure.

— Books on Edwin Land:

Land's Polaroid: A Company and the Man Who Invented It by Peter C. Wensberg (Founders #263)

A Triumph of Genius: Edwin Land, Polaroid, and the Kodak Patent War by Ronald Fierstein (Founders #134)

Land's Polaroid: A Company and the Man Who Invented It by Peter C. Wensberg (Founders #133)

The Instant Image: Edwin Land and the Polaroid Experience by Mark Olshaker (Founders #132)

Insisting On The Impossible: The Life of Edwin Land and Instant: The Story of Polaroid(Founders #40)

— Biography about Steve Jobs: Becoming Steve Jobs: The Evolution of a Reckless Upstart into a Visionary Leader by Brent Schlender and Rick Tetzeli

— Edwin Land of Polaroid talked about the intersection of the humanities and science. I like that intersection. There's something magical about that place. There are a lot of people innovating, and that's not the main distinction of my career. The reason Apple resonates with people is that there's a deep current of humanity in our innovation. I think great artists and great engineers are similar, in that they both have a desire to express themselves. In fact some of the best people working on the original Mac were poets and musicians on the side. In the seventies computers became a way for people to express their creativity. Great artists like Leonardo da Vinci and Michelangelo were also great at science. Michelangelo knew a lot about how to quarry stone, not just how to be a sculptor. — Steve Jobs: The Exclusive Biography by Walter Isaacson (Founders #214)

— Book on Henry Ford:

I Invented the Modern Age: The Rise of Henry Ford by Richard Snow (Founders #9)

The Autobiography of Henry Ford by Henry Ford (Founders #26)

Today and Tomorrow Henry Ford (Founders #80)

My Forty Years With Ford by Charles Sorensen (Founders #118)

The Story of Henry Ford and Thomas Edison's Ten Year Road Trip by Jeff Guinn (Founders #190)

— Another parallel to Jobs: Land's control over his company was nearly absolute, and he exercised it to a degree that was compelling and sometimes exhausting.

— When you read a biography of Edwin land you see an incredibly smart, gifted, driven, focused person endure decade after decade of struggle. And more importantly —finally work his way through.

— Another parallel to Jobs: You may be noticing that none of this has anything to do with instant photography. Polarizers rather than pictures would define the first two decades of lands intellectual life and would establish his company. Instant photos were an idea that came later on, a secondary business around which his company was completely recreated.

— “Missionaries make better products.” —Jeff Bezos

— His letter to shareholders gradually became a particularly dramatic showcase for his language and his thinking. These letters-really more like personal mission statements-are thoughtful and compact, and just eccentric enough to be completely engaging. Instead of discussing earnings and growth they laid out Land's World inviting everyone to join.

— Land gave him a four-word job description: "Keeper of the language.”

— No argument in the world can ever compare with one dramatic demonstration. — My Life in Advertising by Claude Hopkins (Founders #170)

— The leap to Polaroid was like replacing a messenger on horseback with your first telephone.

— Hire a paid critic:

Norio Ohga, who had been a vocal arts student at the Tokyo University of Arts when he saw our first audio tape recorder back in 1950. I had had my eye on him for all those years because of his bold criticism of our first machine.

He was a great champion of the tape recorder, but he was severe with us because he didn't think our early machine was good enough. It had too much wow and flutter, he said. He was right, of course; our first machine was rather primitive. We invited him to be a paid critic even while he was still in school. His ideas were very challenging. He said then, "A ballet dancer needs a mirror to perfect her style, her technique.

— Made in Japan: Akio Morita and Sony by Akio Morita.

— Another parallel to Jobs: Don't kid yourself. Polaroid is a one man company.

— He argued there was no reason that well-designed, wellmade computers couldn't command the same market share and margins as a luxury automobile.

A BMW might get you to where you are going in the same way as a Chevy that costs half the price, but there will always be those who will pay for the better ride in the sexier car. Rather than competing with commodity PC makers like Dell, Compaq and Gateway, why not make only first-class products with high margins so that Apple could continue to develop even better first-class products?

The company could make much bigger profits from selling a $3,000 machine rather than a $500 machine, even if they sold fewer of them.

Why not, then, just concentrate on making the best $3,000 machines around? — Jony Ive: The Genius Behind Apple's Greatest Products by Leander Kahney.

— How To Turn Down A Billion Dollars: The Snapchat Story by Billy Gallagher

— Books on Enzo Ferrari

Go Like Hell: Ford, Ferrari, and Their Battle for Speed and Glory at Le Mans by A.J. Baime. (Founders #97)

Enzo Ferrari: Power, Politics, and The Making of an Automotive Empire by Luca Dal Monte (Founders #98)

Enzo Ferrari: The Man and The Machine by Brock Yates (Founders #220)

— Soul in the game. Listen to how Edwin Land describes his product:

We would not have known and have only just learned that a new kind of relationship between people in groups is brought into being by SX-70 when the members of a group are photographing and being photographed and sharing the photographs: it turns out that buried within us—

there is latent interest in each other; there is tenderness, curiosity, excitement, affection, companionability and humor; it turns out, in this cold world where man grows distant from man,

and even lovers can reach each other only briefly, that we have a yen for and a primordial competence for a quiet good-humored delight in each other:

we have a prehistoric tribal competence for a non-physical, non-emotional, non-sexual satisfaction in being partners in the lonely exploration of a once empty planet.

— “Over the very long term, history shows that the chances of any business surviving in a manner agreeable to a company’s owners are slim at best.” —Charlie Munger

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

A Triumph of Genius: Edwin Land, Polaroid, and the Kodak Patent War

The Vagabonds: The Story of Henry Ford and Thomas Edison's Ten-Year Road Trip

How to Turn Down a Billion Dollars: The Snapchat Story

Land's Polaroid: A Company and the Man Who Invented It

Enzo Ferrari: Power, Politics and the Making of an Automobile Empire

Insisting On The Impossible: The Life Of Edwin Land (Sloan Technology Series)

The Instant Image: Edwin Land and the Polaroid experience

Becoming Steve Jobs: The Evolution of a Reckless Upstart into a Visionary Leader

Jony Ive: The Genius Behind Apple's Greatest Products

My Life in Advertising and Scientific Advertising

I Invented the Modern Age: The Rise of Henry Ford

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Learning Leader Show

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

The Learning Leader Show With Ryan Hawk

Full show notes at www.LearningLeader.com

My books:

Welcome to Management - https://amzn.to/3XWyZAH

The Pursuit of Excellence - https://amzn.to/4eX9vtP

The Score That Matters - https://amzn.to/3zPub7Z

Seth Godin is the author of 21 international bestsellers that have changed the way people think about work and art. They have been translated into 38 languages. His breakthrough books include Purple Cow, Tribes, The Dip, Linchpin, and his latest book is called This is Strategy. He writes one of the most popular daily blogs in the world and has given 5 TED talks. He is the founder of the altMBA, and the former VP of Direct Marketing at Yahoo!

Notes:

"If you want word of mouth, you have to create something remarkable, and that means it’s worthy of remark."
The elegant path is the most useful way forward. “My neighbor is a barefoot runner. He glides without apparent effort.” Elegance is simplicity, efficiency, and effectiveness.
Dorothy and Her Crew. How did Dorothy persuade the Lion, Tin Man, and Scarecrow to join her on the trip to see the Wizard? Did she make a case about how much she missed home? No. She created the conditions where the others could get what they wanted by joining her.
Seeing Strategy Clearly. Strategy is a flexible plan that guides us as we seek to create a change. It helps us make decisions over time while working within a system.
Low-Hanging Fruit Isn’t. It’s all been picked. The easy, direct, obvious paths are unlikely to get you the results you’re working so hard to obtain. In fact, these paths are probably a trap.
Seth, at one point, got 800 rejection letters. Have to keep going...
"I wouldn't call Steve Ballmer a good leader."
An example of Seth making a difference... He went to Kenya and talked with 60 people who started a book club based on his book Linchpin. "They decided to be leaders."
Make decisions in the moment:
- Examine the issue
- Get feedback
- Look for patterns
"Taste is knowing what the market wants before it knows it."
Rick Rubin
- Reality distortion field
- Johnny Cash
- "What do you think?"
"Objections are your friends."
What are the commonalities among leaders with whom Seth has worked and who have sustained excellence? They are all different, but the one thing they have in common is they all have chosen to be leaders. And that means that they are here to make a change happen.
Management doesn’t just exist. It was invented. When you race to the bottom, You see people as resources, not as people.
Questions That Lead To Strategies. 84 questions. They’ll force you to think through your strategy. By answering them, you’ll be better prepared to make a difference… And make a ruckus. Some of them: Who is this project for? What is my timeline? What systems would need to change for my project to succeed? Where will I cause tension? What resistance should I anticipate? Where is the empathy? What asset would transform my project? What can I learn from comparable projects? Is the change I’m making contagious? Can I make it easier for others to decide? How can I design for network effects? What are common objections I expect to encounter?

The Pursuit of Excellence: The Uncommon Behaviors of the World's Most Productive Achievers

Welcome to Management: How to Grow From Top Performer to Excellent Leader

The Score That Matters: Growing Excellence in Yourself and Those You Lead

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Rich Roll Podcast

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Tom Holland is the star of Spider-Man, a nascent entrepreneur, and one of Hollywood’s most grounded young actors.

This conversation traverses the nexus of fame, personal growth, and Tom’s journey toward sobriety, which catalyzed his foray into the non-alcoholic beverage industry. We explore his evolution from child actor to global superstar, his therapeutic relationship with golf, and how he’s remained attuned to his authentic self amidst Hollywood’s gilded chaos.

Tom candidly reflects on navigating the intricacies of the Marvel Cinematic Universe and his recent return to the verité of Shakespearean theatre.

Tom’s infectious enthusiasm is palpable. Enjoy!

Show notes + MORE
Watch on YouTube
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Doctor's Farmacy with Mark Hyman, MD

Key Takeaways * The benefits of conventional medicine for surgical intervention, emergencies, and palliative care can’t be understated but the field falls short in identifying the root cause of illness and taking preventive action * Appointments no one should skip: Annual check-up with primary care doctor, colonoscopy + Your annual checkup may seem futile and outdated but some tests are better than no tests to establish a baseline + Colon cancer is preventable and treatable * Appointments men should not skip: Prostate exam * Appointments women should not skip: Gynecological exam & mammograms

Read the full notes @ podcastnotes.org

Are you up to date on the doctor appointments that could save your life? In this episode, I dive into the essential screenings you can’t afford to skip, from mammograms and colonoscopies to functional lab tests that reveal much more than standard checkups. We’ll break down how conventional medicine is great for emergency care and early detection, but it often misses the root causes of illness.
View Show Notes From This Episode
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Art of Manliness

Money can't buy happiness. It sounds good as a bumper sticker platitude.

But the truth is, money can buy happiness. At least sometimes. In certain circumstances. If we view it and use it in the right ways.

Here to unpack the conditions under which money can buy happiness and facilitate our flourishing is Dr. Daniel Crosby, a psychologist and behavioral finance expert and the author of The Soul of Wealth: 50 Reflections on Money and Meaning. Today on the show, Daniel shares the minimum income level at which money buys happiness, at least in the sense of avoiding pain. We talk about how to purchase material things in a way that increases happiness, while avoiding materialism, and the value of using your money to buy health and freedom. And we discuss the importance of finding an overarching why that guides the way you allocate your money and doing a values audit to see if your purpose and spending habits are aligned.

Resources Related to the Podcast Daniel's previous appearances on the AoM podcast: + Episode #222: The Laws of Wealth + Episode #511: Mastering the Psychology of Investing * AoM Podcast #659: Do You Want to Be Rich or Wealthy? (And Why the Difference Matters) * AoM Podcast #321: How to Think About Money * "Experiences Won’t Make You Happier Than Possessions" * Die with Zero* by Bill Perkins

Connect With Daniel Crosby* Daniel on X * Daniel's podcast, Standard Deviations * Daniel on LinkedIn

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Founders✓Claim

Key Takeaways * Some failure is inevitable; learn from it, do not beat yourself up over it, and keep moving forward * Business is not a battle to be waged; it is a puzzle to be solved * True entrepreneurs never fail; sometimes the business venture doesn’t work out for them, but they never fail * Go to where it is less crowded; there is no substitute for limited competition * Be someone that people make money with * Have a long-term view and do not sacrifice your ability to do future deals by burning bridges to close the current one * If you love what you do, then you will get really good at it and do it for a long time;money will come as a result * The true test of an entrepreneur is someone who spends his life constantly testing his limits * “Fear and courage are cousins – and very closely related.” – Sam Zell

Read the full notes @ podcastnotes.org

What I learned from reading Money Talks, Bullsh*t Walks: Inside the Contrarian Mind of Billionaire Mogul Sam Zell by Ben Johnson.

Ramp gives you everything you need to control spend, watch your costs, and optimize your financial operations —all on a single platform. Make history's greatest entrepreneurs proud by going to Ramp and learning how they can help your business control your costs and save more.

Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast. Get access to Founders Notes here.

Join my free email newsletter to get my top 10 highlights from every book

Follow Founders Podcast on YouTube (Video coming soon!)

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

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Culture Apothecary with Alex Clark

Key Takeaways * Understanding Big Food: Ten companies own the entity of our food system – these companies have outsized control over our food system, and they care more about profits than human health * Our ancestors would not recognize the “foods” that we eat today; most people do not realize that new ingredients have been snuck into our food supply over the last fifty years * Following World War II, in search of a new market, the chemical companies shifted their focus towards American farmlands and launched a new war on the bugs and pests on American farmlands * The World Health Organization classifies glyphosate as a known carcinogen, and yet, approximately 280 billion pounds of glyphosate are sprayed on American crops per year; about 80-90% of grain products on grocery store shelves contain very high levels of glyphosate * Companies such as Bayer make the chemicals that destroy our soil and give us cancer, then also produce and profit from drugs designed to treat those cancers * Studies that go against the interests of the agrochemical companies are rare because those same chemical companies fund the majority of the research in the industry * The way that we are farming now is not sustainable; if we continue down our current path of spraying all these chemicals on our food and destroying the soil, then we will only have 55 years of harvests left before plantable soil is gone * The fruits and vegetables in the grocery store are losing vitamin and mineral content because the soil they were harvested in is not as healthy as it once was * Approximately 77% of adults between the ages of 17 and 24 are ineligible for military service due to obesity * Tips from Courtney Swan: Buy organic, buy local produce from nearby farmers, form a relationship with a local rancher, shop the perimeter of the grocery store, buy real foods with simple ingredients, prioritize protein, and eliminate ultra-processed foods

Read the full notes @ podcastnotes.org

An integrative nutritionist on a mission to change how America eats, Courtney Swan (aka @realfoodology on Instagram and host of the podcast of the same name) educates Alex on glyphosate, GMOs, how to start shopping for real food, and why parents need to choose between wellness and illness for their kids.Thank you to our sponsors!Masa Chips | Use code "REALALEXCLARK" for 20% OFFWise Traditions | Use code “ALEX” for $25 OFFNimi Skincare | Use code "ALEXCLARK" for 10% OFFYRefy | Call (888) 502-2612Courtney SwanInstagram | @RealfoodologyYouTube | @RealfoodologyWebsite | www.realfoodology.comRealfoodology Podcast | @RealfoodologyAlex Clark Instagram | @realalexclarkInstagram | @popliticsFacebook | @realalexclarkX (Twitter) | @yoalexrapzYouTube | @RealAlexClarkSpotify | @Culture ApothecaryApple Podcasts | @Culture Apothecary'Culture Apothecary' Merch OUT NOW! Glass tumblers, weekly wellness planners, hats, crewnecks and more. Use code "ALEXCLARK" for 10% OFFJoin the Cuteservatives Facebook group to connect with likeminded friends who love America and all things health and wellness!Subscribe to ‘Culture Apothecary’ on Apple Podcasts and Spotify. New episodes drop 6pm PST/ 9pm EST every Monday and Thursday.This show is made possible with generous donations from listeners who believe in our mission to heal a sick culture. You can support our show by leaving a tax deductible donation, or by subscribing to @realalexclark YouTube for FREE!

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Artificial Intelligence Podcast

Key Takeaways * The soul is the battleground between the forces of good and evil; it is your moral duty to constrain evil within yourself * Communism does not scale and it does not iterate – whereas religious thought is the record of those ideas that have scaled and iterated * If you follow the voice of adventure and make the necessary sacrifices to follow the path that takes you out of your comfort zone, then you will experience the following benefits: + Your life will be a blessing + Everyone will hold you in high esteem + You will establish something of permanent value + You will do these things in a way that is maximally beneficial to everyone else * There is no distinction between the truest adventure of life and taking on the maximal responsibility and burden * Compare yourself to who you were yesterday, not to who someone else is today * Make the presumption that if you move forward in good faith, whatever happens to you will be the best thing that could happen – no matter what it is * Men should have a temper, but they should be able to regulate it; most of what passes for morality is nothing but cowardice * A good man has to be formidable: The capacity that could be the most potent force for evil can also be the most powerful force for good * Welcome the adversity of life as a redemptive challenge; the best parts of yourself activate when you voluntarily contend with challenges * After you go through a period of pain, you will have more gratitude for the ordinariness of life * We have an existential moral duty to aim upward and to tell the truth

Read the full notes @ podcastnotes.org

Jordan Peterson is a psychologist, author, lecturer, and podcast host.
Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep448-sc
See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc.

Transcript:
https://lexfridman.com/jordan-peterson-2-transcript

CONTACT LEX:
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EPISODE LINKS:
Peterson Academy: https://petersonacademy.com
Jordan's X: https://x.com/jordanbpeterson
Jordan's YouTube: https://www.youtube.com/@JordanBPeterson
Jordan's Website: https://jordanbpeterson.com

Jordan's Books:
We Who Wrestle with God: https://amzn.to/485Dz4a
Beyond Order: https://amzn.to/3T4LRBw
12 Rules for Life: https://amzn.to/3c4sqYF
Maps of Meaning: https://amzn.to/3A1Ods2

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OUTLINE:
(00:00) - Introduction
(07:07) - Nietzsche
(14:48) - Power and propaganda
(19:54) - Nazism
(24:54) - Religion
(41:18) - Communism
(47:03) - Hero myth
(49:12) - Belief in God
(59:24) - Advice for young people
(1:12:02) - Sex
(1:32:00) - Good and evil
(1:44:46) - Psychopathy
(1:58:15) - Hardship
(2:10:31) - Pain and gratitude
(2:21:32) - Truth

PODCAST LINKS:
- Podcast Website: https://lexfridman.com/podcast
- Apple Podcasts: https://apple.co/2lwqZIr
- Spotify: https://spoti.fi/2nEwCF8
- RSS: https://lexfridman.com/feed/podcast/
- Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4
- Clips Channel: https://www.youtube.com/lexclips

Maps of Meaning: The Architecture of Belief

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Econtalk

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Friedrich Hayek credited Bruno Leoni with shaping his ideas on laws and legislation. James Buchanan said that Leoni identified problems that led to his own work on public choice. How is it possible, then, that so few of us know of the groundbreaking Italian political philosopher? Listen as Duke economist Michael Munger talks with EconTalk's Russ Roberts about Leoni's ideas and the gruesome murder that ended his life before its time.

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"History 102" with WhatifAltHist's Rudyard Lynch and Erik Torenberg

Key Takeaways * Our society obsesses over African slavery; it has become a deep psychological neurosis that tears society apart * Africa had three different slave trades from the Middle Ages to the 20th century + The internal African slave (the largest) + The Muslim slave trade (selling slaves to the Muslim world; 2nd largest) + The Western European slave trade (3rd largest) * Throughout human history, Africa was the place that the most slaves were pulled out of – contrasted with other areas such as Europe and Asia, which had centralized governments that were able to protect their citizens * Once Africa became a part of the global economy, it realized that it could offer slaves in exchange for goods and services * The vast majority of people involved in the African slave trade were black * “I don’t think any serious historian could ever support the 1619 Project who is not an ideologue. It’s not even a historical argument; it’s a political argument masquerading through history.” – Rudyard Lynch * Because America was so wealthy, African-American slaves had a higher quality of living than the peasantries of Europe did; however, African-American slaves were disenfranchised from any sort of respect or social standards * “I think the British ending slavery in the 1830s and 40s is one of the most admirable things a country has done.” – Rudyard Lynch + The West practiced slavery, but it was also a society that ended it – which is historically rare * As religions developed and spread around the globe, they eventually abolished slavery among their people

Read the full notes @ podcastnotes.org

In this episode of History 102, WhatifAltHist creator Rudyard Lynch and Erik Torenberg discuss the history of the Muslim slave trade, a forgotten tragedy that predates and rivals the Atlantic slave trade in both scale and brutality.

Dive into the complex dynamics and enduring impact of this dark chapter in African history, and explore the Muslim and internal slave trades while also challenging the 1619 Project's narrative. Learn about the broader context of global slavery, the complex origins of racial inequality, and the global network that fueled the transatlantic slave trade.

🔥 Apply to join over 400 founders and Execs in the Turpentine Network: https://hmplogxqz0y.typeform.com/to/JCkphVqj

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RECOMMENDED PODCAST:
🎙️ Second Opinion - A new podcast for health-tech insiders from Christina Farr of the Second Opinion newsletter. Join Christina Farr, Luba Greenwood, and Ash Zenooz every week as they challenge industry experts with tough questions about the best bets in health-tech.
Apple Podcasts: https://podcasts.apple.com/us/podcast/id1759267211
Spotify: https://open.spotify.com/show/0A8NwQE976s32zdBbZw6bv
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Complex Systems with Patrick McKenzie
Patrick McKenzie (@patio11) talks to experts who understand the complicated but not unknowable systems we rely on. You might be surprised at how quickly Patrick and his guests can put you in the top 1% of understanding for stock trading, tech hiring, and more.
Spotify: https://open.spotify.com/show/3Mos4VE3figVXleHDqfXOH
Apple: https://podcasts.apple.com/us/podcast/complex-systems-with-patrick-mckenzie-patio11/id1753399812
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This show is produced by Turpentine: a network of podcasts, newsletters, and more, covering technology, business, and culture — all from the perspective of industry insiders and experts. We’re launching new shows every week, and we’re looking for industry-leading sponsors — if you think that might be you and your company, email us at erik@turpentine.co.

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RELATED EPISODE/S:
Rise of Islam: https://podcasts.apple.com/us/podcast/rise-of-islam/id1730633913?i=1000659000133

–

FOLLOW ON X:
@whatifalthist (Rudyard)
@eriktorenberg (Erik)
@TurpentineMedia

–
TIMESTAMPS:
(00:00) Introduction
(00:42) African Slave Trade Basics
(01:42) Misconceptions and Context
(03:20) Different African Slave Trades
(03:25) Muslim Slave Trade
(14:19) Sponsor: beehiiv | Babbel
(20:49) Comparisons with the Atlantic Slave Trade
(41:34) Impact of Slavery on America
(55:09) Slavery in Brazil and the Caribbean
(58:30) Book Recommendations
(59:10) Wrap
--
BOOK RECOMMENDATIONS:

African Founders by David Hackett Fisher

Conquests and Cultures by Thomas Sowell

Africa by John Reeder

Africa and the Africans by John Thornton

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Doctor's Farmacy with Mark Hyman, MD

Key Takeaways * Everything sold at Whole Foods, Erewhon, or other specialty stores is not healthy; become a savvy shopper and don’t fall into the trap + Be wary of packaging: “If it has a health claim, it’s not good for you.” – Mark Hyman * The more ultra-processed foods make up your diet, the less nutritious your diet tends to be overall and the greater risk you are of developing chronic inflammatory diseases + For every 10% of your diet that comes from ultra-processed foods, the risk of death increases by 14% * The real risks of ultra-processed foods: Increase in cardiovascular death, increased risk of anxiety and depression, higher risk of type II diabetes, increased risk of Alzheimer’s, increased risk of sleeping disorder, obesity * How did we get here? Simply put, there’s a lot of money to be made by special industries and the government * Solution: Ban pharmaceutical ads on TV and ads specifically targeting children

Read the full notes @ podcastnotes.org

Have you ever wondered why it’s so hard to put down that bag of chips? In this episode, my guests Dr. Shebani Sethi and Calley Means and I break down how ultra-processed foods are contributing to the obesity epidemic, diabetes, heart disease, and even mental health issues. From understanding the science of addiction to decoding food labels, we’ll explore how big food companies are manipulating us—and what we can do to fight back.
View Show Notes From This Episode
Get Free Weekly Health Tips from Dr. Hyman
Sign Up for Dr. Hyman’s Weekly Longevity Journal
Full-length episodes of these interviews can be found here:
Why the Last Thing that Should Ever Eat is Ultra Processed Foods: It Kills 11 Million People a Year
How Does Ultra-Processed Food Affect Our Mental Health?
Calley Means: The Obesity Crisis, Ozempic, ADHD and Food Industry Lies
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Culture Apothecary with Alex Clark

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Raw milk farmer, Rick Anglin, used to be in the conventional dairy industry before switching to raw milk. His farm, Fond du Lac Farms, is the exclusive raw dairy provider to Sprouts grocery stores across the state of Arizona. Does hot coffee pasteurize raw milk? What is the listeria risk from consuming raw dairy? Should you only drink raw milk from grass-fed cows? Farmer Rick joins Alex to put raw milk conspiracies out to pasture.

Thank You To Our Sponsors!Squeezed Juice | Use code “Alex” for 25% OFF at ⁠shop.squeezedjuice.com ⁠Garnuu | Use code “Alex” for 15% OFF at ⁠garnuu.com⁠Yrefy | Call (888) 502-2612 or visit ⁠yrefy.com

Rick Anglin

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Subscribe to ‘Culture Apothecary’ on ⁠Apple Podcasts⁠ and ⁠Spotify⁠. New episodes drop 6pm PST/ 9pm EST every Monday and Thursday.

This show is made possible with generous donations from listeners who believe in our mission to heal a sick culture. You can support our show by leaving a tax deductible donation, or by subscribing to ⁠⁠@RealAlexClark⁠⁠ YouTube for FREE! ⁠⁠donate.tpusa.com⁠⁠

cultureapothecary #alexclark #rawmilk #diet #food

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Write of Passage Podcast

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

You know him as the CEO of OpenAI — but did you know that Sam Altman is an avid writer?

As one of today’s most successful entrepreneurs, Sam champions the tremendous value of writing: how it clarifies your thinking, expands your ideas, and levels-up your life in every sense, both personally and professionally. Plus, he has a love for the creative. (Have you ever met someone who can recite Percy Bysshe Shelley poems from memory? Well, Sam can.)

In this episode, we discuss how Sam uses ChatGPT in his daily life; how LLMs are changing the future of writing; what it means to be a novelist in the age of technology; and Sam’s best-learned writing lessons from Paul Graham. If you want to learn how the king of ChatGPT writes, this episode is for you.

SPEAKER LINKS:
Website: https://openai.com/
Blog: https://blog.samaltman.com/
Twitter: https://twitter.com/sama

WRITE OF PASSAGE:
Want to learn more about the final class for Write of Passage?
Click here: https://writeofpassage.com/

PODCAST LINKS:
Website: https://writeofpassage.school/how-i-write/
YouTube: https://www.youtube.com/@DavidPerellChannel/videos
Apple: https://podcasts.apple.com/us/podcast/how-i-write/id1700171470
Spotify: https://open.spotify.com/show/2DjMSboniFAeGA8v9NpoPv
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Found My Fitness - Rhonda Patrick

Key Takeaways * Microplastics don’t just vanish in our bodies, they accumulate; by understanding the sources, we can take preventive measures to avoid or minimize the use of harmful products * Once microplastics enter our bodies, they can circulate in our bloodstream and deposit in various tissues and the bloodstream + As our environmental plastic pollution increases, so does the accumulation in human tissue + While the body does have mechanisms to clear toxins, we’re in an almost constant cycle of consuming and clearing microplastics and associated chemicals (BPA, BPS, phthalates) * Top sources of microplastic and chemical exposure: Water (both tap and bottled), air, synthetic clothing, food packaging, cookware * Microplastics play an active role in damaging our organs, disrupting our hormones, impacting fertility, causing cancer, and possibly increasing the risk of neurodegenerative disease * Strategies to reduce exposure to microplastics and associated chemicals: (1) Try to avoid packaged food, and especially heating food in plastic; (2) Consider setting up reverse osmosis filtration at home; (3) Reduce consumption of canned foods; (4) Use a mug or bring your own to a coffee shop; (5) Opt for cookware made of titanium, ceramic, cast iron; (6) Drink from glass bottles instead of plastic or cans; (7) Use a HEPA filter at home; (8) Try to wear clothing made of natural fibers like cotton, bamboo, linen, silk * Be a savvy consumer: Many products labeled as BPA free still contain BPS (which is equally harmful) or phthalates (arguably more harmful)

Read the full notes @ podcastnotes.org

Sweating helps enhance microplastic-associated chemical excretion. Get my free sauna report when you sign up here for my newsletter.

Discover my premium podcast, The Aliquot

Every week, the average person ingests the equivalent weight of a credit card in plastic.* While certain preventive measures can significantly reduce your intake of these harmful substances, it’s crucial to acknowledge a more daunting concern: the bioaccumulation of microplastics in the brain, potentially at ten times the rate of other organs. Microplastics and their associated chemicals are alarmingly ubiquitous — they permeate breast milk, sperm, the hippocampus, the prefrontal cortex, the air we breathe, medications, the water supply, and our bloodstream, accumulating in most major organ systems. During this episode, we’ll explore the unsettling realities of microplastics and their associated chemicals, diving into how they infiltrate nearly every facet of our environment and body, and discuss actionable strategies to reduce exposure.

Timestamps:

(00:00) The extent of the problem
(02:12) Top sources of exposure
(04:00) Contamination of our water
(05:04) BPA, phthalates, & PFAS (forever chemicals)
(07:06) How heating plastic affects BPA exposure
(09:21) Our unfortunate habit of eating credit cards
(11:33) Microplastics in major organs
(14:05) Crossing the blood-brain barrier
(15:01) How microplastics affect a developing fetus
(15:55) The bloodstream is a highway for microplastics
(18:12) Endocrine and hormonal effects
(23:09) Consequences in pregnant women
(25:35) How phthalates affect reproductive health
(26:36) BPA's involvement in autism spectrum disorder
(29:58) Side effects of prenatal BPA exposure
(32:18) The brain may be a super-accumulator of plastic
(34:50) Human brain microplastic levels are rising
(36:06) Lost fertility in women
(38:07) Changes in sperm quality
(39:23) Microplastics in sperm
(40:59) Why the heart suffers
(42:51) Microplastics in arterial plaque
(43:56) How BPA affects blood pressure
(45:58) Risk of cancer
(50:31) Topo Chico sparkling water
(53:02) Reverse osmosis filtration
(54:56) Food-based strategies for limiting microplastics
(56:32) The "myth" of BPA-free plastics
(58:14) Is salt a source of microplastics?
(59:18) HEPA filters
(1:00:52) Choose your clothing wisely
(1:01:47) How to prevent release of microplastics (from laundry)
(1:02:32) Receipts and thermal paper
(1:04:17) Microplastic excretion and breakdown
(1:06:28) Sulforaphane for detoxifying
(1:08:38) Can dietary fiber increase microplastic excretion?
(1:10:15) Are plastic chemicals excreted through sweat?
(1:11:21) Do excretion strategies work for "forever chemicals"?

Show notes are available by clicking here

Watch this episode on YouTube

* Some sources suggesting this figure may need to be revised downward as a result of some disagreement on the math used. However, in spite of this lack of consensus, the human and animal intake of microplastics is substantial and pervasive.

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Lenny's Podcast: Product | Growth | Career✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Jonny Miller is the founder of Nervous System Mastery, a course that has helped hundreds of founders and tech leaders cultivate calm, reduce nervousness, enhance resilience, and elevate their sense of aliveness. Having personally benefited from Jonny’s teachings, I’m especially excited to have him on the show. In this episode, we discuss:

• How shifting your focus from the mind to the body can help ease nervousness

• The power of breath in changing states

• The importance of “interoception”

• Specific breathing exercises to both calm and excite your nervous system

• The A.P.E. (awareness, posture, and emotion) framework for recognizing body signals

• The “feather, brick, dump truck” phenomenon

• The concept of emotional debt and how to release it

• The competitive advantage of feeling emotions

—

Jonny’s five-week boot camp, Nervous System Mastery, will equip you with evidence-backed protocols to cultivate greater calm and agency over your internal state. Learn to rewire maladaptive stress responses and improve your sleep (use code LENNY for $250 discount). Apply here.

—

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Find the full transcript at: https://www.lennysnewsletter.com/p/managing-nerves-anxiety-and-burnout

—

Where to find Jonny Miller:

• X: https://twitter.com/jonnym1ller

• LinkedIn: https://www.linkedin.com/in/jonnym1ller/

• Website: https://www.jonnymiller.co/

• Podcast: podcast.curioushumans.com

• Email: jonny@curioushumans.com

• Course: https://nsmastery.com/lenny

—

Where to find Lenny:

• Newsletter: https://www.lennysnewsletter.com

• X: https://twitter.com/lennysan

• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/

—

In this episode, we cover:

(00:00) Jonny’s background

(07:19) The bottom-up approach to nervousness and anxiety

(09:42) The power of breath in changing states

(11:47) The concept of state over story

(13:56) Personal experiences with nervousness

(15:01) Breathing exercises to calm you down

(20:40) The “espresso” breath exercise to give you energy

(25:44) Interoception and the A.P.E. framework

(34:47) The “feather, brick, dump truck” phenomenon

(37:40) Recognizing emotional debt and avoiding burnout

(40:47) Using somatic-oriented therapy for healing

(45:26) Telltale signs of emotional debt

(48:13) The competitive advantage of “feeling the feels”

(50:20) Advice for people overwhelmed by stimuli

(52:36) The NSDR (non-sleep deep rest) practice for emotional release

(55:38) Daily practices for emotional well-being

(58:23) Thoughts on meditation

(01:01:26) The Body Keeps the Score

(01:01:58) Contrarian corner

(01:04:43) Lightning round

—

Jonny’s If [This] Then [Breathe] Recipes:

• If [overwhelmed], then [hum]

• If [anxious], then [breath of calm]

• If [lethargic], then [espresso breath]

—

Referenced:

• The Operating Manual for Your Nervous System: https://every.to/p/the-operating-manual-for-your-nervous-system

• Afferent vs. Efferent Neurons: https://www.osmosis.org/answers/afferent-vs-efferent-neurons

• Insular cortex: https://en.wikipedia.org/wiki/Insular_cortex

• Jonny’s TED Talk, “The gifts of grief”: https://www.ted.com/talks/jonny_miller_the_gifts_of_grief/details

• Humming (Simple Bhramari Pranayama) as a Stress Buster: A Holter-Based Study to Analyze Heart Rate Variability (HRV) Parameters During Bhramari, Physical Activity, Emotional Stress, and Sleep: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182780/

• 14-Minute Guided NSDR (non-sleep deep rest) practice: https://www.youtube.com/watch?v=vjXX2c72fYY

• Breathing Techniques to Reduce Stress and Anxiety | Dr. Andrew Huberman on the Physiological Sigh: https://www.youtube.com/watch?v=kSZKIupBUuc

• Interoception: the hidden sense that shapes well-being: https://www.theguardian.com/science/2021/aug/15/the-hidden-sense-shaping-your-wellbeing-interoception

• Exteroception: https://dictionary.apa.org/exteroception

• Interoceptive Awareness and ADHD: https://chadd.org/adhd-news/adhd-news-adults/interoceptive-awareness-and-adhd/

• Childhood Trauma Affects Stress-Related Interoceptive Accuracy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813623/

• The Hour Between Dog and Wolf: How Risk Taking Transforms Us, Body and Mind: https://www.amazon.com/Hour-Between-Dog-Wolf-Transforms/dp/0143123408

• Somatic Experiencing: https://www.somaticexperiencing.com/

• Hakomi Institute: https://hakomiinstitute.com/

• Decisions and Desire (about Antonio Damasio’s work): https://hbr.org/2006/01/decisions-and-desire

• When enough is enough | Andy Johns (ex-FB, Twitter, Quora): https://www.lennyspodcast.com/when-enough-is-enough-andy-johns-ex-fb-twitter-quora/

• What Is Yoga Nidra?: https://health.clevelandclinic.org/what-is-yoga-nidra

• Becoming Fully Yourself, What AI Wants, Family Rituals & Rites of Passage, with Kevin Kelly: https://podcast.curioushumans.com/episodes/becoming-fully-yourself-what-ai-wants-rites-of-passage-with-kevin-kelly

• Tim Ferriss: https://tim.blog/

• The Power of Sensations: Intermediate’s Vipassana Body Scan: https://insighttimer.com/carola.ananda/guided-meditations/the-power-of-sensations-intermediates-vipassana-body-scan-meditation

• Vipassana Meditation: https://www.dhamma.org/en/index

• The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma: https://www.amazon.com/Body-Keeps-Score-Healing-Trauma/dp/0670785938

• Waking the Tiger: Healing Trauma: https://www.amazon.com/Waking-Tiger-Healing-Peter-Levine/dp/155643233X

• Consolations: The Solace, Nourishment and Underlying Meaning of Everyday Words: https://www.themarginalian.org/2015/04/29/david-whyte-consolations-words/

• The 15 Commitments of Conscious Leadership: A New Paradigm for Sustainable Success: https://www.amazon.com/15-Commitments-Conscious-Leadership-Sustainable/dp/0990976904/

• The Conscious Leadership Group: https://conscious.is/

• Recapture the Rapture: Rethinking God, Sex, and Death in a World That’s Lost Its Mind: https://www.amazon.com/Recapture-Rapture-Rethinking-Death-World/dp/0062905465

• Kubo and the Two Strings on Prime Video: https://www.amazon.com/Kubo-Two-Strings-Charlize-Theron/dp/B01K5BSWX0

• Wolfwalkers on AppleTV+: https://tv.apple.com/us/movie/wolfwalkers/umc.cmc.amuoq00hqelfi98j0gvg641x

• Scavengers Reign on Max: https://www.max.com/shows/scavengers-reign/50c8ce6d-088c-42d9-9147-d1b19b1289d4

• Jerry Colonna on LinkedIn: https://www.linkedin.com/in/jerry-colonna-reboot/

• Ra Optics “Sunset” blue-light blockers: https://raoptics.com/collections/night-lenses

• Nurosym vagal stimulation device: https://my.nurosym.com/vns1564/

• Pulsetto vagal stimulation device: https://pulsetto.tech/new-year/?gc_id=20124962116&h_ad_id=686249897188&gad_source=1

• Apollo vagus nerve stimulator: https://apolloneuro.com/products/apollo-wearable

—

Additional research:

• Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging: https://www.sciencedirect.com/science/article/pii/S0306453023003001

• Somatic experiencing: using interoception and proprioception as core elements of trauma therapy: https://www.frontiersin.org/articles/10.3389/fpsyg.2015.00093/full

• Relationship between interoception and emotion regulation: New evidence from mixed methods: https://www.sciencedirect.com/science/article/abs/pii/S0165032718323723

• Out-of-the-blue panic attacks aren’t without warning: body sends signals for hour before: https://pubmed.ncbi.nlm.nih.gov/21783179/

—

Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.

—

Lenny may be an investor in the companies discussed.

Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

Recapture the Rapture: Rethinking God, Sex, and Death in a World That's Lost Its Mind

The Hour Between Dog and Wolf: How Risk Taking Transforms Us, Body and Mind

The 15 Commitments of Conscious Leadership: A New Paradigm for Sustainable Success

The Body Keeps the Score: Brain, Mind, and Body in the Healing of Trauma

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Invest Like the Best

Key Takeaways * “The founder has to be accountable for the story. The founder holds this secret knowledge and vision that other people do not.” – Lulu Meservey * Go Direct: If the founder’s secret has to go through seven layers of filtering before it is shared with the world, then it will become something that is already familiar to people and that already exists * The Core Ingredients of Founder Communications: + 1. Have a willingness and eagerness to take on the company’s comms + 2. Have a clear vision of the company’s goals + 3. Know your audience + 4. Reach people where they intellectually hang out * “Communication is a vector, not a scalar. It only matters if there is a direction attached to it.” – Lulu Meservey * Know your audience; if you are talking to the wrong people, then you would be better off talking to nobody because you may be making new enemies or unwanted friends * Do not worry about converting your haters into believers; doing so successfully is so rare that it is probably not worth your scare time * Know where your target audience intellectually hangs out so that your message can reach them in that medium * Do not worry about converting your haters into believers; doing so successfully is so rare that it is probably not worth your scare time * Craft your hook and know the erogenous zone of your target audience, then present them with a “gateway drug” that bridges them into the new world that you are creating

Read the full notes @ podcastnotes.org

My guest today is Lulu Meservey. Lulu is the Founder and CEO of Rostra, a company that partners with founders to level up their communications around all strategic initiatives, from hiring to fundraising. She is also on the board at Shopify. I have been recently fascinated by the challenge of founders telling their story and Lulu is an expert in comms and a believer in creative problem-solving through effective communication and compelling storytelling. We discuss the evolution of media and its pitfalls, innovative methods for managing crises, and the power of going direct with your communication. Please enjoy my conversation with Lulu Meservey.

I’m excited to announce that we are hiring an Editor in Chief at Colossus. This will be a critical and central role in our growing media platform and in our quest to find and showcase the best people, businesses, and ideas in the world. This person will work on existing shows like Invest Like the Best and Founders, our soon-to-be-announced print publication, and more. We aim to be the dominant media company exploring business and investing frontiers, so this person needs to be obsessed with these topics and bring serious operational chops. I firmly believe this role can help define someone’s career. Go to joincolossus.com/eic to apply.

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For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.
—
This episode is brought to you by Alphasense. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Imagine completing your research five to ten times faster with search that delivers the most relevant results, helping you make high-conviction decisions with confidence. AlphaSense provides access to over 300 million premium documents, including company filings, earnings reports, press releases, and more from public and private companies. Invest Like the Best listeners can get a free trial now at Alpha-Sense.com/Invest and experience firsthand how AlphaSense and Tegas help you make smarter decisions faster.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
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Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).
Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:06:48) The Evolution of Media and Communication
(00:11:25) The Importance of Direct Communication for Founders
(00:20:20) Choosing the Right Partners and Clients
(00:25:20) The Art of Launching a Product
(00:34:01) Fundraising Tips for Entrepreneurs and Investors
(00:35:32) The Pitfalls of Inauthentic Fundraising
(00:36:05) Crafting a Compelling Macro Narrative
(00:37:54) Crisis Management Strategies for Founders
(00:42:41) Lessons from Counterinsurgency
(00:44:24) The Rugby Analogy for Founders
(00:49:34) The Power of K-Pop Marketing
(00:56:30) Vision and Future of Rostra
(01:01:17) The Importance of Direct Communication
(01:10:36) The Kindest Thing Anyone Has Done For Lulu

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Shawn Ryan Show

Key Takeaways * Populism in the new Communism; the same strategies that were used to fight and combat the spread of Communism during the Cold War are now used to fight populism * Global censorship is not a “left vs right” issue; it is the Blob vs. populism + The “Blob” as a term used to describe the entrenched foreign policy establishment in Washington, DC * Following World War II, the Blob was created to influence events in foreign countries so that those events would suit the interests of the United States + After 1948, the United States needed a new mechanism to maintain its empire – not by military means, but by political vassalage + The US would intervene in countries that did not pose any national security threat but had resources or services that supported the interests of the US and its people * Starting in 2016, the foreign-policy established institutions felt threatened that the entire rules-based international order might collapse due to nations pursuing their own nationalism; to combat this trend, the Blob created its online censorship apparatus around the year 2014 + The Blob is used to prevent or handicap the rise of populist political candidates in a given region + During the Cold War, the CIA and State Department viewed left-wing Communism as the ultimate threat; today, they view right-wing populism as the threat * The US encourages nations to “strengthen its political process” by establishing robust counter-disinformation mechanisms so that it can be aligned with “democracy best practices” * Government funding is being used to subsidize a censorship mercenary army; the complex would cease to exist if its funding was cut off + “The American people are subsidizing their silence.” – Mike Benz * If the censorship-industrial complex reaches full maturity, then it will become as powerful as the military-industrial complex itself

Read the full notes @ podcastnotes.org

Mike Benz is a former official with the U.S. Department of State, known for his work in international communications and digital freedom. He has played a significant role in advocating for internet freedom and the protection of online expression.
Benz is the founder of the Foundation for Freedom Online, an organization dedicated to promoting free speech and digital rights around the world. His work focuses on countering authoritarian censorship and supporting the rights of individuals to access and share information freely.
His background includes expertise in foreign affairs and digital policy, often emphasizing the importance of a free and open internet as a fundamental human right. Through his advocacy, Benz has sought to engage policymakers and the public on issues related to digital governance, censorship, and the implications of technology for democracy.

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The Lunar Society

Daniel Yergin Books * “The Allies floated to victory on a sea of oil.” – Lord Curzon + Access to oil resources was critical for the Allies’ military operations, fueling their ships, planes, and machinery; this provided the Allies with a mobility advantage over the Germans * Hydrocarbons have been the engine of economic development * “World War II was not an oil war, but there was an oil war within World War II.” – Daniel Yergin + When Hitler invaded Russia, he was not only going for Moscow but also for the oil fields in Baku + Admiral Nimitz said if the Japanese had come back a third time and hit the oil tanks, then World War II in the Pacific would have taken another two years + One reason why the Japanese Kamikaze flew into the aircraft carriers was to save fuel so that they did not have to fly back * Energy security as a national strategic imperative tends to fall out of focus until it hits you in the face * Warfare tends to be a beta-test environment for new technologies: World War I began with calvary and ended with tanks, airplanes, and motorcycles * After World War I, there were fears that the country would run out of oil; to mitigate this fear, the American government began to support American companies that wanted to expand into the Middle East * Six out of every seven barrels of oil used by the Allies in WWII were produced by the United States * After World War II, all world leaders understood the significance of securing oil as a strategic resource * Estimates suggest that by 2030, about 10% of electricity in the United States will go towards powering data centers; today, that figure is 4%

Read the full notes @ podcastnotes.org

Unless you understand the history of oil, you cannot understand the rise of America, WW1, WW2, secular stagnation, the Middle East, Ukraine, how Xi and Putin think, and basically anything else that's happened since 1860.

It was a great honor to interview Daniel Yergin, the Pulitzer Prize winning author of The Prize - the best history of oil ever written (which makes it the best history of the 20th century ever written).

Watch on YouTube. Listen on Apple Podcasts, Spotify, or any other podcast platform. Read the full transcript here. Follow me on Twitter for updates on future episodes.

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Timestamps

(00:00:00) – Beginning of the oil industry

(00:13:37) – World War I & II

(00:25:06) – The Middle East

(00:47:04) – Yergin’s conversations with Putin & Modi

(01:04:36) – Writing through stories

(01:10:26) – The renewable energy transition

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The Prize: The Epic Quest for Oil, Money and Power

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Artificial Intelligence Podcast

Key Takeaways * The key to understanding Ancient Rome is to understand that it was obsessed with the past * The Romans were hyper-competitive and cared deeply about their status amongst their peers; their public competitiveness drove them * One of the secrets to Rome’s success was its ability to absorb and integrate non-Roman ideas * “If we were to write a realistic textbook of the Roman Empire, nine out of ten chapters should be details of what it was like to be a small-time family farmer, because that’s what 90% of the people in the ancient world did.” – Gregory Aldrete * Roman law is perhaps the most significant legacy the empire has left on the modern world; about 90% of the modern world uses some derivation of it * The Great Contradiction: Rome’s very success made almost every group within Roman society deeply unhappy and boiling with resentment * Caesar succeeded in taking over the state as one man, but he could not solve the problems of ruling Rome as one person and appearing to function as a king * Augustus is one of the most significant individuals in Roman history given he was the one who founded the Roman Empire; he led the transition from the republic to empire * Public speaking was an essential aspect of life in Rome; those who were great orators, such as Cicero, had a great advantage in seeking power and influence * While Gladiators were considered low status – because they performed for others – many of them became wildly popular in Roman culture * The Five Good Emperors period (96-180 CE) of Roman history is often seen as a high point in Roman history + The five emperors were Nerva, Trajan, Hadrian, Antoninus Pius, and Marcus Aurelius * Eventually, the Roman Empire became too large to effectively govern; a state of constant civil war ensured, which created a vicious downward cycle for the overall Roman economy that left it poorer and more vulnerable to fragmentation * Different historians attribute the fall of the Roman Empire to different things, citing the barbarians, Christianity, climate, disease, and moral decline

Read the full notes @ podcastnotes.org

Gregory Aldrete is a historian specializing in ancient Rome and military history.
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OUTLINE:
(00:00) - Introduction
(08:38) - Ancient world
(22:34) - Three phases of Roman history
(25:24) - Rome's expansion
(37:04) - Punic wars
(45:36) - Conquering Greece
(47:14) - Scipio vs Hannibal
(50:21) - Heavy infantry vs Cavalry
(53:57) - Armor
(1:06:48) - Alexander the Great
(1:12:49) - Roman law
(1:22:29) - Slavery
(1:30:09) - Fall of the Roman Republic
(1:33:54) - Julius Caesar
(1:38:33) - Octavian's rise
(1:48:25) - Cleopatra
(1:56:47) - Augustus
(2:24:57) - Religion in Rome
(2:49:03) - Emperors
(2:56:10) - Marcus Aurelius
(3:02:21) - Taxes
(3:05:29) - Fall of the Roman Empire
(3:22:41) - Decisive battles
(3:46:51) - Hope

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How to Take Over the World

The story of how John Wooden won ten national championships on the way to becoming the greatest coach of all time.

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Drive with Dr. Peter Attia

Key Takeaways * In medicine (and everywhere), there is a resistance to new ideas, tied to effort justification – the idea that you’ve spent so much time holding a certain belief, that the cost is too high to change * Nothing in science is not 100% certain – there are no proofs; science is not a ‘thing’ it’s a process + You shouldn’t cling to hypotheses with absolute certainty and should be open to updating beliefs based on new information + “Just having a crazy idea is not sufficient. You have to have a means of stating what a hypothesis is, determining how to test that hypothesis, and above all else – having the ability to update your hypothesis based on new, emerging information.” – Peter Attia * The distrust in science and medicine is because there is no humility in walking back incorrect information; it’s created two camps: (1) Blind faith in science and medicine; (2) Complete rejection of science and medicine + “Women are confused because the same megaphone used to say estrogen causes breast cancer has not been used to correct course.” – Peter Attia * Don’t throw out the baby with the bath water: “C-sections and antibiotics have saved more lives than anything that we’re doing today. That has doubled the human lifespan.” – Peter Attia * The vast majority of what we call ovarian cancer is a fallopian tube cancer + We need to increase public awareness, we’re targeting the wrong organ + At Johns Hopkins, fallopian tubes are removed instead of tied to eliminate the 1 in 78 chance of getting ovarian cancer * Difficulty in advancing knowledge: People are doing things in a blackhole with no scientific evidence – we need appropriate studies but the NIH controls $80 billion in research dollars + The NIH doesn’t fund big, new ideas – it funds small ideas that are a likely bet + We don’t have a vehicle to encourage big thinkers

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Marty Makary, a Johns Hopkins surgeon and New York Times bestselling author, returns to The Drive to discuss his latest book, Blind Spots: When Medicine Gets It Wrong, and What It Means for Our Health. In this episode, Marty explores how a new generation of doctors is challenging long-held medical practices by asking critical new questions. He discusses the major problems of groupthink and cognitive dissonance in the medical community and delves into several of the "blind spots" raised in the book, including treatments for appendicitis, the peanut allergy epidemic, misunderstandings about HRT and breast cancer, antibiotic use, and the evolution of childbirth. He explains the urgent need for reform in medical education and the major barriers standing in the way of innovative medical research. Throughout the conversation, Marty offers insightful reflections on where medicine has succeeded and where there’s still room to challenge historic practices and embrace new approaches.

We discuss:

The issue of groupthink and cognitive dissonance in science and medicine [2:30];
How a non-operative treatment for appendicitis sheds light on cognitive dissonance [7:00];
How cognitive dissonance and effort justification shape beliefs and actions [13:15];
How misguided peanut allergy recommendations created an epidemic [17:45];
The enduring impact of misinformation and fear-based messaging around hormone replacement therapy allegedly causing breast cancer [25:15];
The dangers of extreme skepticism and blind faith in science, and the importance of understanding uncertainty and probability [28:00];
The overuse of antibiotics and the rise of antibiotic resistant infections and poor gut health [33:45];
The potential correlations between early antibiotic use and chronic diseases [40:45];
The historical and evolving trends in childbirth and C-section rates [50:15];
Rethinking ovarian cancer: recent data challenging decades of medical practice and leading to new preventive measures [1:05:30];
Navigating uncertainty as a physician [1:19:30];
The urgent need for reform in medical education [1:21:45];
The major barriers to innovative medical research [1:27:30];
The dogmatic culture of academic medicine: why humility and challenging established norms are key for progress [1:38:15];
The major successes and ongoing challenges of modern medicine [1:51:00]; and
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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Art of Manliness

Although they may call it different things and approach its attainment in different ways, many of the world’s religions and philosophies have a similar goal: achieving a life of virtue, peace, and flourishing.

In his new book, Seriously Happy, Ben Aldrige explains how anyone can use the wisdom of ancient traditions to improve themselves and live the Good life. Today on the show, Ben offers a thumbnail sketch of Buddhism, Cynicism, Taoism, Stoicism, Epicureanism, and Aristotelianism, along with practices and challenges inspired by these philosophies, including walking a banana, listening to a music performance without music, and taking a Wu Wei adventure, that you can use to put ancient wisdom into action and become a better and happier man.

Resources Related to the Podcast Ben’s previous appearance on the AoM podcast: Episode #640 — Weird and Wonderful Ways to Get Comfortable Being Uncomfortable * AoM Podcast #148: Trying Not to Try * Why Buddhism is True: The Science and Philosophy of Meditation and Enlightenment* by Robert Wright * John Cage’s 4’33” * Albert Ellis’ Rational Emotive Behavior Therapy

Connect With Ben Aldridge* Ben’s website

Why Buddhism is True: The Science and Philosophy of Meditation and Enlightenment

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The Tucker Carlson Show

Key Takeaways * The state of bewilderment that we are currently living through is beneficial to those in power because it grants them more control * Those in power benefit from bewilderment, conflict, and chaos because it is easier to assert authority in these environments * When a state of crisis benefits those in power, you can expect a perpetual state of crisis * The state attempts to emulate the characteristics of God: omniscience, omnipresence, omnipotence, and glory * “Secularism is all well and good, as long as the state doesn’t behave like a god.” – Russell Brand * If you have a deep need for God, then be careful because the culture will try to fill that desire with false gods such as drugs, alcohol, money, and fame * See every person that you come across as a human being; be open to the idea that God is trying to speak to you through another person * If our communities are guided by God, then it is more likely that we will create communities, states, nations, and a planet of peace and prosperityfrom the bottom up, and not from the top down * While technology has created the possibility of further decentralization of power, crises are being used to legitimize decentralization; those in power prefer the trajectory of totalitarianism and technological feudalism under the peculiar veil of kindness and protection * Protection and control exist on a continuum; this dynamic is fine for a parent who is looking after her child, but not for a state and its people

Read the full notes @ podcastnotes.org

Tucker Carlson Live Tour in Phoenix, AZ. Russell Brand on his baptism and God’s role in the battle against totalitarianism in the west.

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Honestly with Bari Weiss ✓ Claim

Key Takeaways * In the United States, free speech is not a right granted by the government but is considered an unalienable right of a human being * But free speech is viewed differently in the European Union; for example, the French view free speech as needing to strike a balance between the individual and the community * It was revealed during the “Twitter Files” controversy that American lobbyists wanted to push America more towards the European model of policing speech online * The state has figured out how to turn the Internet into an instrument of social control * Counter-terrorism to Counter-populism: Many of the government agencies that once focused on stopping terrorist groups have shifted their focus inward domestically to monitor and censor American citizens * The state uses “misinformation” as a pretext for guiding messaging * The gradual drift towards authoritarianism: People come to worship authority when the state “saves” them from every “emergency” * Be wary of Language Inflation: A phenomenon in which extreme language is used to describe something that does not warrant the use of extreme language * There is a natural political bias in government-sponsored censorship; the people who fill government censorship positions tend to come from left-leaning universities

Read the full notes @ podcastnotes.org

In the past few weeks, there’s been an increasing number of threats to freedom of speech around the world.

In France, authorities arrested Telegram CEO Pavel Durov for failing to adequately moderate content and prevent criminal activity on his platform.

In the UK, since the outbreak of anti-immigration riots, police have arrested individuals merely for posting comments online. The Labour-led government has suggested expanding measures to remove “legal but harmful” content.

In Brazil, President Lula’s administration has proposed new regulations requiring social media companies to monitor and remove “harmful content,” and a Brazilian Supreme Court justice just banned X altogether in the country. The ruling came after the platform missed a deadline to name a new legal representative there.

From Hungary to Pakistan, the right to speak your mind, particularly on the internet, is more precarious than ever.

Even in the United States, with our free speech rights enshrined in the Constitution, polls suggest an entire generation has grown up thinking it should be illegal to say something inaccurate or hateful. Democratic VP nominee Tim Walz said as much: “There’s no guarantee to free speech on misinformation or hate speech, and especially around our democracy.”

So how did we get here? And, where is this all going?

Today, Michael sits down with the intrepid journalist Matt Taibbi, who knows this issue inside out. When The Free Press launched, he reported the Twitter Files with Bari Weiss, and together they exposed how government agencies had pressured Twitter to censor undesirable information, including skepticism of Covid lockdowns and opposition to Covid-related public school closures.

In this conversation, Matt and Michael talk about what’s happening in Europe, Brazil, and here in the U.S. They discuss the factors that precipitated the so-called “misinformation wars,” from 9/11 to Brexit and Trump’s election, that convinced elites of the need to enforce restrictions on speech. And they talk about why these efforts are doomed to backfire.

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Modern Wisdom

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Eric Weinstein is a mathematician, economist, former Managing Director of Thiel Capital and a podcaster.
It feels like the world is reaching a fever-pitch. From deep fakes to cheap fakes, AI girlfriends to senile presidents, we've never had more access to information, and yet it's never been harder to work out what is true. So, what do we do?
Expect to learn Eric’s thoughts on the 2024 presidential election, whether we are being gaslit on a global scale by the media, the future of string theory and what's next for theoretical physics, why we have canned humour and what that means as a society, Eric’s thoughts on Joe Rogan, what my biggest weaknesses as a human are and much more…
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577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

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700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

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Found My Fitness - Rhonda Patrick

Key Takeaways * Tips for maintaining consistency: (1) What gets you excited to work out?; (2) What exercise do you enjoy and have low pain with?; (3) What will you execute consistently? * Variables for building strength: (1) Mechanical tension; (2) Number of hard sets; (3) Training muscles at long lengths under tension * Factors that increase the risk of injury: (1) Increase in training load and/or volume when you aren’t prepared; (2) Psychological stress – what happens in the mind affects the body (and what happens in the body affects the mind); (3) Sleep quality is a big lever for injury risk and pain management + Form doesn’t move the needle on injury risk – tissue adaptation matters more * “The best time to start lifting weights is right now.” – Layne Norton + Have joint pain or never exercised? Start with lighter weights and movements that either don’t cause pain or induce less pain + It almost doesn’t matter what you start with – do whatever keeps you consistent * Most practical tip for protein intake: Shoot for about 1g/lb bodyweight – or more depending on goals, but consume as much as you want balancing other macros to be properly fueled for exercise and recovery * Seed oils are contributing to the health crisis – but probably not because they’re inherently bad + Seed oils are not innocuous but energy toxicity is a big chunk of what’s happening, we’re eating too much and moving too little + Seed oils are also more representative of consuming more processed foods + Bottom line: There is no strong evidence to avoid seed oils, as long as you’re still controlling for overall diet quality and calories – focus on diet quality and the bigger picture * “Have guidelines, not rules.” – Layne Norton * Most people believe what they want to believe regardless of the evidence * Sticking to water is good, but if you switch to no- or low-calorie drink from full calories, it will save a ton of calories * Keeping your body fat down is the best way to protect your health; how you get there is less important than getting there – the most important thing is consistency * Supplements won’t do the work for you but they might help you recover faster

Read the full notes @ podcastnotes.org

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Dr. Layne Norton is a Ph.D. in Nutritional Sciences, a professional bodybuilder, and a champion powerlifter. We discuss why most people aren’t training too hard, when to go to failure, whether seed oils are “the” central cause of chronic disease, why having a slow metabolism isn’t a credible reason for being overweight (for most), and the sustaining power of good habits. We also get into controversies around the carnivore diet, diet sodas, artificial sweeteners, intermittent fasting, and much more.

Timestamps:

(00:00) Introduction
(04:48) Layne's coaching philosophy
(14:39) Why to start tracking calories (for at least 3 days)
(17:41) Why people lie to themselves about food intake
(23:06) The profound benefits of small exercise doses
(26:53) Why you should treat exercise like brushing your teeth
(30:11) Benefits of resistance training for older individuals
(33:51) Should you train to failure?
(47:07) Why hard training & consistency trump exercise selection
(56:46) Is lifting heavy necessary for building muscle?
(57:54) Barbell vs. hack squats for preventing falls
(1:00:10) Can lifting weights decrease low-back pain?
(1:01:43) Injury prevention when resistance training
(1:11:16) How exposure therapy can help you with injuries
(1:15:04) Why pain doesn't always indicate tissue injury
(1:18:17) Should you resistance train after a poor night of sleep?
(1:21:57) Why menopause can cause weight gain
(1:29:36) Why it's never too late to start lifting weights
(1:32:05) Resistance training tips for older individuals with joint pain
(1:36:18) Why total protein intake matters more than distribution
(1:44:19) Layne's daily protein distribution
(1:46:44) The shortcomings of nutrition studies
(1:54:06) Is consuming more than 1.6 g/kg of protein beneficial?
(1:55:33) Should you eat more protein in a calorie deficit?
(1:56:43) Protein intake for endurance athletes
(1:58:07) How much protein does Layne eat?
(1:59:11) Are seed oils a predominant cause of chronic disease?
(2:08:45) Does the carnivore diet increase heart disease risk?
(2:14:16) Are heated seed oils more inflammatory?
(2:20:33) Is there a "big food" industry conspiracy?
(2:26:17) Are sugar-sweetened beverages uniquely deleterious?
(2:30:17) Can diet soda help you lose weight?
(2:34:20) Microbiome & cancer risks of diet soda
(2:42:02) Is drinking 1 Diet Coke per day unhealthy?
(2:44:24) Why Layne rarely takes a strong position on early science
(2:49:04) Carnivore diet
(3:01:52) Time-restricted eating
(3:12:38) Layne's daily routine
(3:16:55) Layne's diet and supplements
(3:19:49) Creatine and hair loss
(3:22:49) Rhodiola rosea & ashwagandha
(3:25:54) Layne's tier 2 supplements

Show notes are available by clicking here

Watch this episode on YouTube

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Founders✓Claim

The name of Nobel usually calls to mind Alfred Nobel, inventor of dynamite, and the internationally prestigious prizes that bear his name. But Alfred was only one member of a creative and innovative family who built an industrial empire in prerevolutionary Russia. The saga begins with an emigre from Sweden, Immanuel Nobel, who was an architect, a pioneer producer of steam engines, and a maker of weapons.

Immanuel's sons included Alfred; Robert, who directed the family's activities in the Caspian oil fields; and Ludwig, an engineering genius and manufacturing magnate whose boundless energy and fierce determination created the Russian petroleum industry.

Ludwig's son Emanuel showed similar mettle, shrewdly bargaining with the Rothschilds for control of the Russian markets and competing head-on with Standard Oil and Royal Dutch Shell for lucrative world markets.

Perhaps no family in history has played so decisive a role in building an industrial empire in an underdeveloped but resource-rich nation. Yet the achievements of the Nobel family have been largely forgotten. When the Bolsheviks came to power, Emmanuel had to flee the country disguised as a peasant.

The Nobel empire with its 50,000 workers lay in ruins. An empire which had taken eighty years to design and build, was nearly destroyed, bringing a sudden and bitter end to one of the most remarkable industrial odysseys in world history.

This episode is what I learned from reading The Russian Rockefellers: The Saga of the Nobel Family and the Russian Oil Industry by Robert Tolf.

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“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

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Infinite Loops

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

“We have created for ourselves a world that we didn't evolve for.”

Gurwinder Bhogal is, for my money, one of the most independent, original and insightful thinkers you’ll find in our corner of the internet.

He returns to discuss how willpower and good old-fashioned human agency can help us reclaim our mental sovereignty and escape the “constant avalanche of concerns that are being vomited over us through our laptop screens, our phones, our TV screens, and in conversations.”

For the full transcript, episode takeaways, and bucketloads of other stuff designed to make you go, “Hmm, that’s interesting!” check out our Substack.

Important Links:

Gurwinder's Substack
Gurwinder's Twitter
Gurwinder’s previous Infinite Loops appearance

Show Notes:

“We have created for ourselves a world we didn’t evolve for”
The dogged persistence of our stubborn beliefs
Gamification; generational differences in agency
The societal impact of the education system’s changing priorities
How to zombify a population
Skin in the game: Gurwinder’s guide to reclaiming agency
LLMs, bullshit, and the atomization of culture
How to play better games
Willpower is the bottleneck
Gurwinder as emperor of the world
MORE!

Books Mentioned:

Why Everything is Becoming a Game; by Gurwinder Bhogal
Think Again: The Power of Knowing What You Don't Know; by Adam Grant
The Status Game: On Human Life and How to Play It; by Will Storr
The True Believer: Thoughts on the Nature of Mass Movements; by Eric Hoffer
Why the Mental Health of Liberal Girls Sank First and Fastest; by Jonathan Haidt (After Babel)
America’s Colleges Are Reaping What They Sowed; by Tyler Austin Harper (The Atlantic)
Joe Biden and the Common Knowledge Game; by Ben Hunt (Epsilon Theory)
The Emperor’s New Clothes; by Hans Christian Andersen
Futarchy Details; by Robin Hanson (Overcoming Bias)
The Enlightenment Trilogy; by Jed McKenna
The Weirdest People in the World: How the West Became Psychologically Peculiar and Particularly Prosperous; by Joseph Henrich

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Write of Passage Podcast

Key Takeaways * Writing invokes clarity of thought; it forces you to ensure that every you say is actually correct * Productive writers are always thinking about the topics they write about, even if they are not sitting in front of their computer * The goal of writing is not to convince the reader that you are right, but to force the reader to think about the issue that you are discussing * “The most important article you write is the second article someone reads.” – Ben Thompson * Develop a framework for writing by using “The Writing Machine”: + Have an overall view of the world and how it works + Process news and information as it happens + Fed that information into your worldview machine + The output that this machine churns out is your content

Read the full notes @ podcastnotes.org

What if writing a newsletter could pay your rent? Well, it can. And today, you’re going to learn how.
Ben Thompson makes millions of dollars a year with his writing. He’s the OG of subscription-based newsletter writers. Maybe that’s your dream, too, but you’re plagued by questions like: “What should I write about?” “What’s my business model?” “How do I make my first dollar online?” We’re so glad you asked; because Ben has the answers. In this episode, you’ll learn his exact playbook for how to monetize your writing — not just for right now, but also for the future.
Ben’s blog, Stratechery, is the OG of subscription-based newsletters and actually inspired the creation of Substack. If you’ve ever wondered what a day-in-the-life of someone who makes millions of dollars writing looks like, now’s your chance.

SPEAKER LINKS:
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Twitter: https://twitter.com/benthompson

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The Tucker Carlson Show

Key Takeaways * There have been about five political realignments throughout American history, and we are going through another one right now * The Democratic Party now consists of the elites, and the Republican Party now consists of the middle and working class * The first step towards totalitarianism always begins with censorship * A democracy cannot exist with censorship: Throughout history, the people who were censoring speech always turn out to be the bad guys * Thirty-seven hours after Biden took the oath of office, his administration opened up a portal to the FBI so that it would have access to social media posts across the various platforms * Elon Musk would have the hero of the old Democratic Party; but today, he is its enemy * The most important issues to Robert F. Kennedy Jr. and why he got involved in politics: + End unjust foreign wars + Stop the censorship + Protect the children the emergent chronic disease epidemic * A function of the president is to explain to the country why we should be proud of the people within it * If you vote for Kamala Harris, you are not electing her – you are electing the apparatus around her * “When we destroy nature, we diminish our capacity to sense the divine, to understand who God is, and our own potential and duties are as human beings. ” – RFK Jr

Read the full notes @ podcastnotes.org

When Bobby Kennedy endorsed Donald Trump last week, he burned his boats. There’s no turning back for him, or for American politics. Here’s his first interview since that happened.

(00:00) Get Tickets to Our Live Tour at TuckerCarlson.com
(00:42) RFK Jr. Endorsing Donald Trump
(11:20) Pavel Durov’s Arrest and Censorship
(39:56) America’s Health Crisis
(47:20) Kennedy Meeting with Trump
(53:48) Kamala Harris Refusing to Meet with Kennedy
(59:56) Why Did They Withdraw Secret Service?
(1:09:48) Would Kennedy Accept a Position as CIA Director?
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My First Million

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Episode 622: Sam Parr ( https://x.com/theSamParr ) and Shaan Puri ( https://x.com/ShaanVP ) talk to Jesse Pujji ( https://x.com/jspujji ) about bootstrapping Ampush and the four levers of digital marketing.
—
Show Notes:
(0:00) Unique insight + unfair advantage
(3:05) How Jesse bootstrapped Ampush using GLG
(14:00) Digital marketing in masterclass in 3 minutes
(20:30) How to sell to the ultra rich
(27:38) Red Ventures' Playbook
(32:40) The Four Big Levers
(41:00) Calling Zuck's cell
(46:30) Noah Kagan's $100M mistake at facebook
(58:45) What's the thing you can't not do?
(1:01:00) Nelly performs at Jesse's birthday party

—
Links:
• Gateway X - https://www.gateway.xyz/
• Aux Insights - https://www.auxinsights.com/
• Accordion - https://www.accordion.com/
• GrowthAssistant - https://growthassistant.com/
• GLG Insights - https://glginsights.com/
• Triple Whale - https://www.triplewhale.com/
• Ampush Lead Gen Overview - https://tinyurl.com/mw3f7cbk

—
Check Out Sam's Stuff:
• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth
• Sam’s List - http://samslist.co/

—
Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

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Impact Theory with Tom Bilyeu

Key Takeaways * The West goes through a period of collapse every 250 years or so; we are currently living through a political crisis as well as a demographic and psychological crisis * Three variables that predict when society is trending toward a civil war + 1. Growing inequality + 2. Increasing competition over elite jobs + 3. Stagnating wages * During more tumultuous times, society tends to split into factions; the West is currently split into the political right and left * Humans are tied to the environments that we grew up in, but we did not evolve to develop in the urban environment in which we do * The ability to maintain religion and socialization weakens when society becomes predominantly urban * The rise of anonymous environments in urban settings leads to a breakdown in social cooperation * The “Psychological Plague”:A societal phenomenon where negative emotions, irrational behaviors, and harmful ideologies spread like a disease among people * Society must strike a balance between creating enough social institutions to keep people in check, but not too many or else individualism gets crushed * Religion establishes psychological stability for society; it tells individuals what they should and should not do by establishing social standards * The left is interested in maintaining and growing bureaucracy; it latches onto problems that cannot ever be solved to justify additional funding, thus expanding the bureaucracy further

Read the full notes @ podcastnotes.org

In this riveting episode of "Impact Theory with Tom Bilyeu," host Tom Bilyeu sits down with Rudyard Lynch, a provocative historian and creator of the YouTube channel "What If Alt Hist." Together, they delve into the concept of societal suicide, examining the breakdowns that drive communities to self-destruction. Lynch provides an unsettling perspective on the decline of Western culture, the ramifications of economic policies, and the creeping dangers of technological and governmental control.

Join us as we navigate these complex issues, from the manipulation of money and rising debt, to the socio-political shifts that threaten our future. This episode promises to challenge your perceptions and offer crucial insights into the mechanisms driving our world's turmoil.

SHOWNOTES:
00:00 Doubt cast on election, potential for conflict.
07:38 Budget and election issues lead to parallel governments.
15:02 Right wins geographically, politically, strategically over left.
19:00 Debt is a predictor of societal outcomes.
24:24 Inflating money leads to soaring inequality and housing costs.
26:30 Paying into property is like an insurance.
33:11 Europe and China face currency and economy challenges.
40:42 GDP distorts healthcare impact, Growth Delusion explains.
46:24 Linked historical cycles in global conflicts throughout history.
50:53 Forcing beliefs backfires, causing resentment and failure.
52:41 17th century crisis led to decline of Italy.
58:05 Decentralization crucial to prevent government control through technology.
01:08:17 Friends drink, strengthen neural pathway, seek alternatives.
01:11:07 Gen Z, shape the future, don't be conscripted.
01:16:42 Potential for violence regardless of election outcome.
01:19:13 Immigration impacts voting and job creation.
01:25:18 Appreciate the history, subscribe, be legendary. Peace.

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What's up, everybody? It's Tom Bilyeu here. If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu’s Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you.

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Twenty Minute VC

Kaz Nejatian is Shopify’s VP of Product & Chief Operating Officer. Before Shopify, Kaz founded Kash, a payment technology company which was acquired in 2017 by one of the largest fintech companies in the U.S. Kaz then served as Product Lead for Payments and Billing at Facebook, reducing the barriers for businesses in cash-dependent markets to purchase digital ads without a credit card.

In Today's Episode with Kaz Nejatian We Discuss: 1. Learnings From the Greats:

Mark Zuckerberg: What are Kaz's biggest lessons from working with Zuck? Why does Kaz believe Zuck is massively under-appreciated?
Keith Rabois: What are Kaz's biggest lessons from working with Keith? How did it change how he operates on a day to day basis?
Tobi Lütke: What have been Kaz's biggest lessons from working with Tobi? What has he changed most significantly since working with Tobi?
Shopify: Why We Build Our Own Tools:
Why does Kaz believe it is crucial for Shopify to build their own tools?
When did he doubt this strategy most? What caused him to question it?
Why does Kaz believe the Stripe <> Shopify partnership is the most important in business?
What is the role of a PM at Shopify?
Why do Shopify focus on how not what product is built?
Eight Truths The Startup World Gets Wrong:
Why does Kaz believe "The Lean Startup" has done more damage than any other startup book?
Why does Kaz believe that 90% of companies do not know what they want when they hire?
Why does Kaz believe the way that companies pay their staff is totally wrong?
Why does Kaz believe that most companies pick fights they do not need to pick?
Why does Kaz believe that for 90% of companies remote work is a terrible idea?
Why does Kaz believe that everyone in sales and marketing should be able to code?
Why does Kaz believe that married people with kids are more, not less productive?
Why does Kaz believe that we totally misunderstand divorce rates?

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Art of Manliness

Key Takeaways * Our feet have a memory: they have a certain way that they like to fit inside a shoe * Do not put your footwear next to the fire because the fire will break down the synthetic materials in the shoe * Put a footprint tarp under the tent to protect the bottom lining of the tent * One of the best things you can do to take care of your sleeping bag: When you first wake up in the morning, reverse your sleeping bag and let it air out before you put it back into your backpack * Make sure that you go into your sleeping bag hydrated and ensure that you are not wearing restrictive clothing * Spend more on your sleeping pad than you do on your sleeping bag; get a sleeping pad with the highest R-value that you can afford * Create the “butt divot” to sleep better when camping: Before setting up your tent, make a divot in the ground that is the size of your bottom * Use a fixed-blade knife instead of a folding knife; the fewer moving parts, the better * Get a backpack with a waist belt if you are going to carry something over 20 pounds

Read the full notes @ podcastnotes.org

A fair amount of gear is involved in making a camping or backpacking trip a success, and choosing that gear can be a little intimidating as there are lots of options, and it's expensive to boot.

Here to offer some tips on selecting gear and getting the most out of it is Craig Caudill, an avid outdoorsman, the director and lead instructor of the Nature Reliance School, and the author of Ultimate Wilderness Gear: Everything You Need to Know to Choose and Use the Best Outdoor Equipment. Today on the show, Craig and I discuss some things to know when purchasing things like boots, tents, sleeping bags, and more, and we offer some specific recommendations as to the gear that's worked for us respectively. Craig also offers tips on using outdoor equipment, including how to dry wet boots without damaging them, whether you should put a tarp under your tent, what to do if you get hot and sweaty or cold in your sleeping bag, a hack for sleeping more comfortably on the ground, and the best kind of knife for an outdoorsman to carry.

Resources Related to the Podcast* AoM Article: How to Filter and Purify Water for Traveling, Camping, and Survival * AoM Article: The Benefits of Hammock Camping * AoM Article: How to Pack a Backpack for Backpacking * AoM Article: Two Things You Should Be Doing to Take Better Care of Your Camping Gear * AoM Article: Outdoor Hydration Showdown — Nalgene Bottle vs. Water Bladder * AoM Article: How to Choose the Perfect Survival Knife * Craig's books * Native Summit in Edmond, OK * Brett's Tent: Hubba Hubba 2-Person Backpacking Tent * Hennessy Hammock Tent * Warbonnet Hammock Tents * Military Modular Sleep System * Brett's Sleeping Pad: Big Agnes * Kate's Sleeping Pad: Therm-A-Rest Trail Prolite Apex * Backpacking Cot * Brett's Backpacking Pillow: Sea to Summit Aeros * Brett's Water Bladder: HydraPak Shape-Shift * Craig's Water Filter: Sawyer Mini * Brett's Water Filter: Katadyn Hiker Pro Hand Pump Water Filter * Sawyer Squeeze Water Filter * Brett's Backpacking Stove: Jetboil Stove * Fire-Maple Backpacking Stove * MSR Backpacking Stove * LT Wright Handcrafted Knives * Fast Fire Firestarters * Hill People Gear Backpacks

Connect With Craig Caudill* Nature Reliance School * Craig on IG * Craig on LinkedIn

Jetboil Zip Camping Stove Cooking System, Carbon

Heat Factory SP128 Mini Water Filtration System

Ultimate Wilderness Gear: Everything You Need to Know to Choose and Use the Best Outdoor Equipment

Sawyer Products Squeeze Water Filtration System

Katadyn Hiker Pro Transparent Water Filter, Lightweight, Compact Design for Personal or Small Group Camping, Backpacking or Emergency Preparedness, one Size (8019857)

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My First Million

Key Takeaways * The nine non-obvious lessons that Shaan Puri has learned while building an audience: + 1. Forget the numbers + 2. Find your inner nerd + 3. Build a magnet, not an audience + 4. The First, Last, Best, Worst, Weirdest framework + 5. Use the Five D’s + 6. Nothing is too long, only too boring + 7. Don’t worry about style or production quality + 8. Create a Binge Bank + 9. Be so good that they cannot ignore you

Read the full notes @ podcastnotes.org

Episode 620: Shaan Puri ( https://x.com/ShaanVP ) breaks down the 9 lessons he’s learned while building an audience.
—
Show Notes:
(0:00) Intro
(2:17) Forget the numbers
(6:11) Find your inner nerd
(9:57)Build a magnet
(10:40) First, Last, Best, Worst, Weirdest
(12:40) The thing I wish I knew earlier
(15:53) No such thing as too long
(16:18) A+ content with C- delivery
(17:58) Create a binge bank
(18:32) People don’t want information
(19:55) Be so good they can’t ignore you

—

Get our business idea database here https://clickhubspot.com/mfm

Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

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The Tucker Carlson Show

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Whistleblowers Calley and Casey Means expose how Big Pharma co-opted government agencies and the food industry to poison America and keep us sick. Buy Casey and Calley’s book, “Good Energy” here - https://www.caseymeans.com/goodenergy

(00:00) Art of the Surge
(00:54) Who Are Casey and Calley Means?
(10:16) Seed Oils and the Lies of the Food Pyramid
(25:20) Vaccines for Newborns
(39:41) Why Is the Medical Industry Ignoring This?
(49:38) The Spiritual Crisis
(1:21:35) The Birth Control Pill
(1:36:12) The Rise of Dementia
(1:43:27) Why Obamacare Is Harmful and How to Fix the Medical Industry

Paid partnerships with:
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Invest Like the Best

Key Takeaways * The keys to creating a business culture of excellence: + Have a small number of people who are elite in their field + Compensate them very well + Ensure that compensation and promotion are perfectly tied to performance + Ruthlessly minimize bureaucracy + Celebrate people who do big things with the fewest number of people possible * “Mathematical superintelligence” is a more specific way to refer to artificial general intelligence (AGI) * Mathematical superintelligence is an AI that solves math problems at a superior capability compared to the sum total of all humans on earth * It will be able to solve any problem, but especially those that have a quantitative element or that require quantitative reasoning * The coming years and decades include a $100+ trillion wealth transfer from boomers to millennials; given the company’s customer base, Robinhood is well-positioned to benefit from this wealth transfer * De-emphasize the significance of the “number of people” managed; the desire to manage a larger number of people warps incentives and attracts empire builders instead of problem-solvers * “Sometimes I just read the reviews of the Robinhood credit card app before bed.” – Vlad Tenev * Advice for entrepreneurs: Imagine if Frank Slootman took over your company… What are the ten things that he would do?

Read the full notes @ podcastnotes.org

My guest today is Vlad Tenev. Vlad is the CEO and co-founder of Robinhood. It was such a treat to sit down with him and discuss the behind-the-scenes of a revolutionary business we all know well. He details Robinhood’s journey to zero-cost trading and what it means to build a consumer-centric financial product. Vlad believes in finding the harmonies across mathematics and art and applies this lens to everything he builds. We discuss Robinhood’s new credit card and more products on the horizon, the company’s toughest moments, including the Gamestop episode, and the compelling future of AI in financial services. Please enjoy this conversation with Vlad Tenev.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Ridgeline. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. I think this platform will become the standard for investment managers, and if you run an investing firm, I highly recommend you find time to speak with them. Head to ridgelineapps.com to learn more about the platform.

This episode is brought to you by Tegus, where we're changing the game in investment research. Step away from outdated, inefficient methods and into the future with our platform, proudly hosting over 100,000 transcripts – with over 25,000 transcripts added just this year alone. Our platform grows eight times faster and adds twice as much monthly content as our competitors, putting us at the forefront of the industry. Plus, with 75% of private market transcripts available exclusively on Tegus, we offer insights you simply can't find elsewhere. See the difference a vast, quality-driven transcript library makes. Unlock your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:03:56) The Next Frontier in AI: Reasoning and Logical Deductions
(00:06:19) Challenges and Approaches in AI Development
(00:09:08) Formal Mathematics and AI Integration
(00:11:23) Practical Applications of Mathematical Superintelligence
(00:17:30) Robinhood's Journey to Zero-Cost Trading
(00:24:38) Building a Consumer-Friendly Trading Platform
(00:28:52) Robinhood Gold and the Future of Financial Services
(00:35:51) Understanding Robinhood's Business Model
(00:42:34) Navigating the GameStop Crisis
(00:49:17) Improving Customer Satisfaction
(00:52:43) Reputation Repair
(00:54:52) The Future of Financial Services
(00:59:06) Crypto and AI in Finance
(01:08:09) Building a High-Performance Culture
(01:11:42) The Kindest Thing Anyone Has Ever Done for Vlad

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Deep Questions with Cal Newport✓Claim

Intro * Check out the episode page

Read the full notes @ podcastnotes.org

In this classic episode Cal talks about the elements of the Deep Life. He then answers a variety of questions about work, family, and phone distractions.

Below are the questions covered in today's episode (with their timestamps). Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo

Video from today’s episode: youtube.com/calnewportmedia

Deep Dive: The Elements of the Deep Life [2:31]

How should I get started in a new remote work job? [17:39]
How I time block a purely reactive job? [22:49]
Should I bother capturing tasks that are fast to complete? [26:20]
How do I tame multiple concurrent projects? [29:53]
How do I schedule optional deep work in an exhausting job? [32:51]
How much time is left for family after goals and deep work? [39:56]
Is there such a thing as deep fun? [42:44]
I am addicted to my phone. What do I do? [44:48]
How do I make a big life decision when I have lots of options? [50:35]

Links:

Buy Cal’s latest book, “Slow Productivity” at calnewport.com/slow

Get a signed copy of Cal’s “Slow Productivity” at peoplesbooktakoma.com/event/cal-newport/

Cal’s monthly book directory: bramses.notion.site/059db2641def4a88988b4d2cee4657ba?

Thanks to our Sponsors:

cozyearth.com/cal
mintmobile.com/deep
policygenius.com/deepquestions
blinkist.com/deep

Thanks to Jesse Miller for production, Jay Kerstens for the intro music, Kieron Rees for the slow productivity music, and Mark Miles for mastering.

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School of Greatness

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Have you saved your seats at Summit of Greatness 2024 yet?! Get them before they sell out at lewishowes.com/tickets

In today's episode, we're diving into the powerful journey of Novak Djokovic, who recently clinched Olympic gold in Paris, solidifying his status as one of the greatest athletes of all time. Join us as we explore how Novak has harnessed the power of manifestation to achieve unprecedented success on and off the tennis court. From overcoming a challenging childhood in war-torn Serbia to mastering the mental game that has propelled him to the top, Novak shares his insights on visualizing and realizing your dreams. Whether you're chasing gold or simply striving for personal growth, Novak's story is a testament to the power of belief and perseverance. Let's dive in and get inspired!

In this episode you will learn

How Novak Djokovic uses visualization and manifestation techniques to achieve success, including his recent Olympic gold medal win.
The impact of Novak's upbringing in war-torn Serbia on his resilience and outlook on life.
The significance of love and presence in Novak's approach to life and tennis.
Strategies Novak employs to stay grounded and maintain focus amidst his many achievements.
The importance of finding joy and passion in the journey, rather than just focusing on the destination.

For more information go to www.lewishowes.com/1650

For more Greatness text PODCAST to +1 (614) 350-3960

More SOG episodes we think you’ll love:

Eckhart Tolle – https://link.chtbl.com/1463-pod

Rhonda Byrne – https://link.chtbl.com/1525-pod

John Maxwell – https://link.chtbl.com/1501-pod

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Infinite Loops

Key Takeaways * Investing is a service-based business; focus on the karma! * “The four horsemen of the investment apocalypse are fear, greed, hope, and ignorance. And only ignorance is something that you can address.” – Jim O’Shaughnessy * Take actions that increase the surface area of your luck * Ironically, in a changing world, playing it safe is one of the riskiest things that you can do * Learn how you are going to react to every phase of the market * You have to be selective, but you also have to be okay with rejection * Trust is a function of experience, and experience is a function of time * You do not need to be right every time to dominate; the best traders in history are right just a little more than 50% of the time * How to add value early in your career: Find the 10% of a person’s life that they hate, and make that problem go away for them * The investing industry is based on trust and reputation – it is wise to remember this

Read the full notes @ podcastnotes.org

Let me introduce you to the four horsemen of the investment apocalypse:

Fear.

Greed.

Hope.

Ignorance.

Notice anything?

Three of four are emotions.

I’ve long argued that effective investing is far more about emotional control than technical know-how (although the latter certainly helps!) By hook or by crook, the best investors can find a way to tame their pesky emotional impulses and overcome that primal urge to respond impulsively to panic, passion, or pride.

My guest, the razor-sharp Ateet Ahluwalia, is a veteran trader and investor who has spent well over 15 years at the coalface, from trading at Goldman at the dawn of the financial crisis to his current role as founder and managing director of the venture capital firm Island Green Capital Management. As you’ll hear from our conversation, Ateet has built an insanely deep understanding of the emotional constitution required to succeed in finance and venture capital, which informs his approach to risk management, hiring, investing, due diligence, and everything in between.

I hope you enjoy our wide-ranging conversation, whose implications extend well beyond investing. For episode takeaways, a full transcript, and various other goodies, check out our Substack.

Important Links:

The Thinker and The Prover; by Jim O’Shaughnessy
Ateet’s LinkedIn
Island Green Capital Management

Show Notes:

Why Venture Capitalists Should Shun the Glory
“In a changing world, playing it safe is one of the riskiest things you can do."
Risk: Why Size Matters
The Emotional Constraints of Investing
How to Find Out What Someone Really Wants
The Purifying Power of Mistakes
Pick up the Phone!
Being Humbled by the Market
Public vs Private Investing
Why Hit Rates Matter
Assessing the Macro Position
Bullshitting, Question-Dodging, and Other Red Flags
The Many Bosses of the Venture Capitalist
Be a Painkiller
Ateet as Emperor of the World
MORE!

Books Mentioned:

The Enlightenment Trilogy; by Jed McKenna
Venture Deals: Be Smarter Than Your Lawyer and Venture Capitalist; by Brad Feld & Jason Mendelson
Financial Intelligence: A Manager’s Guide to Knowing What the Numbers Really Mean; by Karen Berman, Joe Knight & John Case
Adventures of a Bystander; by Peter F. Drucker

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Artificial Intelligence Podcast

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Elon Musk is CEO of Neuralink, SpaceX, Tesla, xAI, and CTO of X. DJ Seo is COO & President of Neuralink. Matthew MacDougall is Head Neurosurgeon at Neuralink. Bliss Chapman is Brain Interface Software Lead at Neuralink. Noland Arbaugh is the first human to have a Neuralink device implanted in his brain.

Transcript: https://lexfridman.com/elon-musk-and-neuralink-team-transcript

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EPISODE LINKS:
Neuralink's X: https://x.com/neuralink
Neuralink's Website: https://neuralink.com/
Elon's X: https://x.com/elonmusk
DJ's X: https://x.com/djseo_
Matthew's X: https://x.com/matthewmacdoug4
Bliss's X: https://x.com/chapman_bliss
Noland's X: https://x.com/ModdedQuad
xAI: https://x.com/xai
Tesla: https://x.com/tesla
Tesla Optimus: https://x.com/tesla_optimus
Tesla AI: https://x.com/Tesla_AI

PODCAST INFO:
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OUTLINE:
Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) - Introduction
(09:26) - Elon Musk
(12:42) - Telepathy
(19:22) - Power of human mind
(23:49) - Future of Neuralink
(29:04) - Ayahuasca
(38:33) - Merging with AI
(43:21) - xAI
(45:34) - Optimus
(52:24) - Elon's approach to problem-solving
(1:09:59) - History and geopolitics
(1:14:30) - Lessons of history
(1:18:49) - Collapse of empires
(1:26:32) - Time
(1:29:14) - Aliens and curiosity
(1:36:48) - DJ Seo
(1:44:57) - Neural dust
(1:51:40) - History of brain–computer interface
(1:59:44) - Biophysics of neural interfaces
(2:10:12) - How Neuralink works
(2:16:03) - Lex with Neuralink implant
(2:36:01) - Digital telepathy
(2:47:03) - Retracted threads
(2:52:38) - Vertical integration
(2:59:32) - Safety
(3:09:27) - Upgrades
(3:18:30) - Future capabilities
(3:47:46) - Matthew MacDougall
(3:53:35) - Neuroscience
(4:00:44) - Neurosurgery
(4:11:48) - Neuralink surgery
(4:30:57) - Brain surgery details
(4:46:40) - Implanting Neuralink on self
(5:02:34) - Life and death
(5:11:54) - Consciousness
(5:14:48) - Bliss Chapman
(5:28:04) - Neural signal
(5:34:56) - Latency
(5:39:36) - Neuralink app
(5:44:17) - Intention vs action
(5:55:31) - Calibration
(6:05:03) - Webgrid
(6:28:05) - Neural decoder
(6:48:40) - Future improvements
(6:57:36) - Noland Arbaugh
(6:57:45) - Becoming paralyzed
(7:11:20) - First Neuralink human participant
(7:15:21) - Day of surgery
(7:33:08) - Moving mouse with brain
(7:58:27) - Webgrid
(8:06:28) - Retracted threads
(8:14:53) - App improvements
(8:21:38) - Gaming
(8:32:36) - Future Neuralink capabilities
(8:35:31) - Controlling Optimus robot
(8:39:53) - God

View Details

Econtalk

Key Takeaways * “It is not totally irrational to worry about society suddenly becoming fundamentally hostile to Jews, even in the West.” – Sam Harris * In America, every year after September 11th, Jews have been a greater target of hate crime than any other group in American society, including Muslims and African Americans * Islam expects conquest – this makes it fundamentally different than most other religions * The central message of the Quran is not about love or compassion; instead, its message is that you should fear going to hell * Islam is not a race; it is a set of ideas * The power of bad ideas is much more consequential than the power of bad people * If the Palestinians laid down their arms, there would be peace in the Middle East; if the Jews laid down their arms, there would be genocide * The fate of open societies is at stake today; it is not “just” the rise of Jew hatred * The basis for hope: We are talking about ideas here, and people can change their minds

Read the full notes @ podcastnotes.org

Neuroscientist and author Sam Harris of the podcast Making Sense talks with EconTalk's Russ Roberts about rising Jew-hatred in the West and what Harris sees as the dangers of radical Islam and Jihadism.

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Twenty Minute VC

Key Takeaways * “Extraordinary careers, when you are junior in venture, do not get built sitting behind a desk in an office behind a laptop. You have to be willing to go meet with founders in person, figure out how to understand their business and how to convince them to even spend time with you when you are not one of the big general partners.” – Delian Asparouhov * Startups must have a strong vision for the future of the world, and then build towards making that vision the reality * Young venture capitalists do not focus enough on differentiation; many young VCs spread themselves too thin by focusing on a multitude of sectors * In venture, you have no moat other than your brand; “US dollars” is the product that you deliver – a product that anybody else can deliver * The number one thing that Delian has learned from Peter Thiel: There is always a way to structure your argument so that you are on the winning side no matter what * “People love software because the marginal distribution costs are zero, but perhaps what people need to realize is also that the marginal returns are zero as well because there is no moat.” – Delian Asparouhov * The only rule of the Founders Fund is that there are no rules * Over the next 100-200 years, our biggest geopolitical and moral crisis is humanity speciating by way of artificial selection pressures (such as embryonic scoring and CRISPR DNA changing) and natural selection pressures (such as humans existing on new frontiers, perhaps in space) * Say what you think; it doesn’t really matter how society chooses to react to it

Read the full notes @ podcastnotes.org

Delian Asparouhov is a Partner at Founders Fund and Co-Founder and President of Varda Space Industries, which is building the world's first space factories. At Founders Fund Delian has led deals in the likes of Ramp ($7BN) and Sword Health ($3BN) among others. Before joining Founders Fund, he was a Principal at Khosla Ventures, Head of Growth at Teespring, and Founder of a healthcare company called Nightingale.

In Today's Episode with Delian Asparouhov We Discuss: 1. Venture Capital: Winners, Losers and Everyone Else:

Who are the Top 3 venture firms in the world today according to Delian?
Why does Delian believe that Benchmark are not the firm they were?
Who will be the winners in venture in the next 10 years?
Who will be the losers in venture in the next 10 years?
Inside Founders Fund: What No One Sees:
What are the most important and impactful elements of Founders Fund that no one knows about?
What does Delian believe that the Founders Fund partnership will strongly disagree with him on?
Why does Founders Fund believe the path of most resistance is the best way to make decisions?
What single topic has Delian publicly disagreed with Peter Thiel on most? How did it go?
What Every Young VC Needs to Know:
What are Delian's single biggest tips to young VCs looking to scale the VC ladder today?
What are the five core pillars of venture according to Delian? What should young VCs focus on?
Why does Delian disagree with Founders Fund partners that "the best founders do not need the help of their VCs?"
Does Delian agree with Vinod Khosla that "90% of VCs do detract value?"
What are the biggest ways that Delian believes VCs can and do detract value?
Europe Will Be Third World, Parenting and Marriage:
Why does Delian believe that Western Europe will become like the third world?
What are Delian's single biggest tips on finding a life partner?
What have been the biggest changes to Delian since becoming a father?
What question does no one ask Delian that someone should ask him?

View Details

rational vc

Key Takeaways * Check out the Rational VC website

Read the full notes @ podcastnotes.org

Learn from history's Greatest Minds — and find Timeless ideas you can apply to business and life. Every episode we explore a Lindy book: We strive to become polymaths like our investing and business icons, pulling the Big Ideas from a wide range of disciplines to help us become better investors and operators. For the curious-minded seeking Worldly Wisdom. Join 3,000+ others by subscribing @ rationalvc.com to get free access to essays and exclusive content.

For the video version of this episode click here.

Timestamps:

(00:00) Intro

(08:16) Core Concepts

(12:10) Important Prologue One

(29:10) Important Prologue Two

(45:04) Prologue Three

(49:42) A First Look at Agency

(1:05:00) Ethics Problems in Scaling

(1:09:00) The Minority Rule

(1:29:40) Employment & FU Money, Freedom

(1:47:26) Status, Manners & Competence

(1:49:55) On Taking Risks

(1:55:35) The Intellectual Yet Idiot

(2:04:17) The Lindy Effect Recap

(2:09:10) Deeper Into Agency

(2:11:58) The Illusion of Business Plans

(2:15:00) Charlie Munger, Show Rather Than Be

(2:17:15) Financial Minimalism, Mimesis

(2:24:22) Virtues & Advice for Young People

(2:26:37) The Interventionistas

(2:28:36) Religion, Belief, & SITG

(2:31:10) Most Important, Book 8: Risk & Rationality

(2:51:05) Epilogue

—

Our website (all essays and podcasts): rationalvc.com
Our investment fund: rational.fund
Cyrus' Twitter: x.com/CyrusYari
Iman's Twitter: x.com/iman_olya

—

Referenced Material:

Cyrus on "Financial Minimalism", Viral Essay:
https://www.rationalvc.com/articles/minimalism

Also listen to the prior three podcast episodes - each covered the other books of Taleb's Incerto Series.

—

Disclaimer: The materials provided are solely for informational or entertainment purposes and do not constitute investment or legal advice. All opinions expressed by hosts and guests are solely their own opinions and do not reflect the opinion of their employer(s).

#Timeless #wisdom #knowledge #books #polymaths

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How to Take Over the World

Key Takeaways * “I can accept failure, everyone fails at something. But I can’t accept not trying.” – Michael Jordan * The greats do not cower when they are slighted; instead, their determination only grows further * “I never asked any of my teammates to do something that I wasn’t willing to do myself. If you don’t want to play that way, don’t play that way. I’m not going to do it for you.” – Michael Jordan * Learning is a gift, even when pain is your teacher * It obvious when a person wants to win more than the competition; the world has a way of elevating these people who simply want it more than everyone else * After Michael Jordan’s legendary performance in Game 2 of the 1986 Eastern Conference First Round, where he scored 63 points against the Boston Celtics, Larry Bird famously said: “I think he’s God disguised as Michael Jordan.” * “I’ve missed more than 9,000 shots in my career. I’ve lost almost 300 games. 26 times I’ve been trusted to take the game-winning shot and missed. I’ve failed over and over and over again in my life. And that is why I succeed.” – Michael Jordan

Read the full notes @ podcastnotes.org

"I can accept failure. Everyone fails at something, but I can't accept not trying. I can't accept it." Michael Jordan is one of the greatest basketball players of all time. He's also a great entrepreneur, business owner, and Olympian. In this episode, we cover his remarkable story and talk about the strategies, tactics, and work habits that made him so effective.

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Lenny's Podcast: Product | Growth | Career✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Rory Sutherland is widely regarded as one of the most influential (and most entertaining) thinkers in marketing and behavioral science.He’s the vice chairman of Ogilvy UK, the author of Alchemy: The Dark Art and Curious Science of Creating Magic in Brands, Business, and Life, and the founder of Nudgestock, the world’s biggest festival of behavioral science and creativity. He champions thinking from first principles and using human psychology—what he calls “thinking psycho-logically”—over mere logic. In our conversation, we cover:

• Why good products don’t always succeed, and bad ones don’t necessarily fail

• Why less functionality can sometimes be more valuable

• The importance of fame in building successful brands

• The importance of timing in product success

• The concept of “most advanced, yet acceptable”

• Why metrics-driven workplaces can be demotivating

• Lots of real-world case studies

• Much more

Note: We encountered some technical difficulties that led to less than ideal video quality for this episode, but the lessons from this conversation made it impossible for me to not publish it anyway. Thanks for your understanding and for bearing with the less-than-ideal video quality.

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Find the transcript at: https://www.lennysnewsletter.com/p/what-most-people-miss-about-marketing

—

Where to find Rory Sutherland:

• X: https://x.com/rorysutherland

• LinkedIn: https://www.linkedin.com/in/rorysutherland

• Book: Alchemy: The Dark Art and Curious Science of Creating Magic in Brands, Business, and Life: https://www.amazon.com/Alchemy-Curious-Science-Creating-Business/dp/006238841X

—

Where to find Lenny:

• Newsletter: https://www.lennysnewsletter.com

• X: https://twitter.com/lennysan

• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/

—

In this episode, we cover:

(00:00) Rory’s background

(02:37) The success and failure of products

(04:08) Why the urge to appear serious can be a disaster in marketing

(08:05) The role of distinctiveness in product design

(12:29) The MAYA principle

(15:50) How thinking irrationally can be advantageous

(17:40) The fault of multiple-choice tests

(21:31) Companies that have successfully implemented out-of-the-box thinking

(30:31) “Psycho-logical” thinking

(31:45) The hare and the dog metaphor

(38:51) Marketing’s crucial role in product adoption

(49:21) The quirks of Google Glass

(55:44) Survivorship bias

(56:09) Balancing rational ideas with irrational ideas

(01:06:19) The rise and fall of tech innovations

(01:09:54) Consistency, distinctiveness, and clarity

(01:21:12) Considering psychological, technological, and economic factors in parallel

(01:23:35) Where to find Rory

—

Referenced:

• Google Glass: https://en.wikipedia.org/wiki/Google_Glass

• Meta Portal TV: https://www.meta.com/portal/products/portal-tv/

• Rory’s quote in a LinkedIn post: https://www.linkedin.com/posts/brad-jackson-04766642_the-urge-to-appear-serious-is-a-disaster-activity-7093497742710210560-1LYN/

• The MAYA Principle: Design for the Future, but Balance It with Your Users’ Present: https://www.interaction-design.org/literature/article/design-for-the-future-but-balance-it-with-your-users-present

• Ogilvy: https://www.ogilvy.com/

• MCI: https://www.mci.world/

• Veuve Clicquot: https://en.wikipedia.org/wiki/Veuve_Clicquot

• Why do the French call the British ‘the roast beefs’?: http://news.bbc.co.uk/2/hi/2913151.stm

• The Killing on Hulu: https://www.hulu.com/series/the-killing-f5da5c2d-4626-4ba9-bcf3-ff5f891771fb

• Original The Killing on BBC: https://www.bbc.co.uk/programmes/b017h7m1

• The Mandarin Oriental, Hong Kong: https://www.mandarinoriental.com/en/hong-kong/victoria-harbour

• SAT: https://satsuite.collegeboard.org/sat

• The Widening Racial Scoring Gap on the SAT College Admissions Test: https://www.jbhe.com/features/49_college_admissions-test.html

• What is the age of the captain?: https://www.icopilots.com/what-is-the-age-of-the-captain/

• Octopus Energy: https://octopus.energy/

• Kraken: https://octopusenergy.group/kraken-technologies

• Toby Shannan: https://theorg.com/org/shopify/org-chart/toby-shannan

• Dunbar’s number: Why we can only maintain 150 relationships: https://www.bbc.com/future/article/20191001-dunbars-number-why-we-can-only-maintain-150-relationships

• AO: https://ao.com/

• Zappos: https://www.zappos.com/

• Joe Cano on LinkedIn: https://www.linkedin.com/in/joeycano/

• John Ralston Saul’s website: https://www.johnralstonsaul.com/

• Voltaire’s Bastards: The Dictatorship of Reason in the West: https://www.amazon.com/Voltaires-Bastards-Dictatorship-Reason-West/dp/0679748199

• Psycho-Logic: Why Too Much Logic Deters Magic: https://coffeeandjunk.com/psycho-logic/

• Herbert Simon’s Decision-Making Approach: https://bura.brunel.ac.uk/bitstream/2438/4995/1/Fulltext.pdf

• Robert Trivers’s website: https://roberttrivers.com/Welcome.html

• Crazy Ivan: https://jollycontrarian.com/index.php?title=Crazy_Ivan

• The Joys of Being a Late Tech Adopter: https://www.nytimes.com/2019/08/28/technology/personaltech/joys-late-tech-adopter.html

• Jean-Claude Van Damme: https://en.wikipedia.org/wiki/Jean-Claude_Van_Damme

• Tim Berners-Lee: https://en.wikipedia.org/wiki/Tim_Berners-Lee

• Edward Jenner and the history of smallpox and vaccination: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200696/

• The real story behind penicillin: https://www.pbs.org/newshour/health/the-real-story-behind-the-worlds-first-antibiotic

• What Are Japanese Toilets?: https://www.bigbathroomshop.co.uk/info/blog/japanese-toilets/

• reMarkable: https://remarkable.com/

• Chumby: https://en.wikipedia.org/wiki/Chumby

• Survivorship bias: https://en.wikipedia.org/wiki/Survivorship_bias

• Jony Ive: https://en.wikipedia.org/wiki/Jony_Ive

• Marc Newson’s website: https://marc-newson.com/

• Designing Men: https://www.vanityfair.com/news/business/2013/11/jony-ive-marc-newson-design-auction

• Qantas A330: https://marc-newson.com/qantas-a330/

• Herodotus: https://en.wikipedia.org/wiki/Herodotus

• Big Decision? Consider It Both Drunk and Sober: https://www.forbes.com/sites/chunkamui/2016/03/22/wine-and-sleep-make-for-better-decisions/?sh=5c97fdc524b1

• How Henry Ford and Thomas Edison killed the electric car: https://www.speakev.com/threads/how-henry-ford-and-thomas-edison-killed-the-electric-car.4270/

• Watch Jay Leno get nostalgic and swoon over this 1909 EV: https://thenextweb.com/news/jay-leno-talk-about-electric-car-1909-baker

• Jay Leno’s Garage: https://www.youtube.com/@jaylenosgarage

• Nudgestock: https://nudgestock.com/

• Akio Morita: https://en.wikipedia.org/wiki/Akio_Morita

• Don Norman on LinkedIn: https://www.linkedin.com/in/donnorman/

• What Makes Tesla’s Business Model Different: https://www.investopedia.com/articles/active-trading/072115/what-makes-teslas-business-model-different.asp

• Monica Lewinsky on X: https://x.com/MonicaLewinsky

• Blindsight: The (Mostly) Hidden Ways Marketing Reshapes Our Brains: azon.com/Blindsight-Mostly-Hidden-Marketing-Reshapes-ebook/dp/B07ZKZ5DWF

• Branding That Means Business: https://www.amazon.com/Branding-that-Means-Business-Economist-ebook/dp/B09QBCCH9N

• PwC: https://www.pwc.com

• Ryanair: https://www.ryanair.com

• British Airways: https://www.britishairways.com/

• Wrigley’s began as a soap business: know when to pivot: https://theamericangenius.com/entrepreneur/wrigleys-began-as-soap-know-when-to-pivot/

• Transport for Humans: https://www.amazon.com/Transport-Humans-Perspectives-Pete-Dyson/dp/1913019357

—

Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.

—

Lenny may be an investor in the companies discussed.

Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

Alchemy: The Dark Art and Curious Science of Creating Magic in Brands, Business, and Life

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Founders✓Claim

What I learned from reading What I Talk About When I Talk About Running: A Memoir by Haruki Murakami.

Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast.

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(3:01) No matter how mundane some action might appear, keep at it long enough and it becomes a contemplative, even meditative act.

(4:00) Pain is inevitable. Suffering is optional.

(4:00) The hurt part is an unavoidable reality, but whether or not you can stand anymore is up to the runner himself.

(10:00) You can't fake passion — someone else, that really loves the job, will out run you. Somebody else sitting in some other MBA program has a deep passion for whatever career path you're going down, and they are going to smoke you if you don't have it yourself. — Runnin' Down a Dream: How to Succeed and Thrive in a Career You Love

(12:00) What’s crucial is whether your writing attains the standards you’ve set for yourself. Failure to reach that bar is not something you can easily explain away.

(14:00) Big ideas come from the unconscious. This is true in art, in science and in advertising. But your unconscious has to be well informed, or your idea will be irrelevant. Stuff your conscious mind with information, then unhook your rational thought process. You can help this process by going for a long walk, or taking a hot bath, or drinking half a pint of claret. Suddenly, if the telephone line from your unconscious is open, a big idea wells up within you. — David Ogilvy

(16:00) If you absolutely can't tolerate critics, then don't do anything new or interesting. — Jeff Bezos

(16:00) So the fact that I’m me and no one else is one of my greatest assets.

(19:00) Failure was not an option. I had to give it everything I had.

(19:00) My only strength has always been the fact that I work hard and can take a lot physically. I’m more a workhorse than a racehorse.

(22:00) I was more interested in having finished it than in whether or not it would ever see the light of day.

(26:00) I’m the kind of person who has to totally commit to whatever I do.

(29:00) The entrenched professional is always going to resist far longer than the private consumer. — James Dyson

(34:00) You really need to prioritize in life, figuring out in what order you should divide up your time and energy. If you don’t get that sort of system set by a certain age, you’ll lack focus and your life will be out of balance. I placed the highest priority on the sort of life that lets me focus on writing,

(37:00) You can’t please everybody. If one out of ten enjoyed the place and said he’d come again, that was enough. If one out of ten was a repeat customer, then the business would survive. To put it the other way, it didn’t matter if nine out of ten didn’t like my bar. This realization lifted a weight off my shoulders. Still, I had to make sure that the one person who did like the place really liked it. In order to make sure he did, I had to make my philosophy and stance clear-cut, and patiently maintain that stance no matter what. This is what I learned through running a business.

(40:00) The reason we're surprised is that we underestimate the cumulative effect of work. Writing a page a day doesn't sound like much, but if you do it every day you'll write a book a year. That's the key: consistency. People who do great things don't get a lot done every day. They get something done, rather than nothing. — How To Do Great Work by Paul Graham. (Founders #314)

(41:00) When you follow what you are intensely interested in this strange convergence happens where you're working all the time and it feels like you're never working. — How To Do Great Work by Paul Graham. (Founders #314)

(43:00) No matter how strong a will a person has, no matter how much he may hate to lose, if it’s an activity he doesn’t really care for, he won’t keep it up for long.

(44:00) Nobody ever recommended or even desired that I be a novelist—in fact, some tried to stop me. I had the idea to be one, and that’s what I did.

(45:00) I decided who I want to be, and that is who I am. — Coco Chanel

(46:00) Once, I interviewed an Olympic runner. I asked him, “Does a runner at your level ever feel like you’d rather not run today, like you don’t want to run and would rather just sleep in?” He stared at me and then, in a voice that made it abundantly clear how stupid he thought the question was, replied, “Of course. All the time!”

(47:00) I pity the poor fellow who is so soft and flabby that he must always have "an atmosphere of good feeling" around him before he can do his work. There are such men. And in the end, unless they obtain enough mental and moral hardiness to lift them out of their soft reliance on "feeling," they are failures. Not only are they business failures; they are character failures also; it is as if their bones never attained a sufficient degree of hardness to enable them to stand on their own feet. There is altogether too much reliance on good feeling in our business organizations. — Henry Ford’s Autobiography

(50:00) If I used being busy as an excuse not to run, I’d never run again.

(51:00) Focus and endurance can be acquired and sharpened through training.

(54:00) Exerting yourself to the fullest within your individual limits: that’s the essence of running, and a metaphor for life.

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

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What I Talk About When I Talk About Running

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Tetragrammaton with Rick Rubin✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Ben Patrick, known as the “Knees Over Toes Guy,” is the founder, president, and CEO of Athletic Truth Group (ATG) Online Coaching. Though a longtime basketball player in his youth, Patrick’s three knee surgeries by the age of 18 stopped his athletic career short. After struggling with pain medication addiction and depression, Patrick soon became devoted to physical fitness and rehabilitation, now boasting an NBA-like 42-inch vertical jump. He developed ATG Online Coaching, working to restore the quality of life in individuals struggling with knee injuries and bringing out their full physical potential. In addition to building his training system, Patrick has authored three books, Knee Ability Zero, Back Ability Zero, and ATG for Life, and he has gained a massive social media presence with over 2.5 million followers.

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Founders✓Claim

Key Takeaways * Check Out the Founders Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

What I learned from reading The Nolan Variations: The Movies, Mysteries, and Marvels of Christopher Nolan by Tom Shone.

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(7:00) The only way I know how to work is to sort of burrow in on one project very obsessively.

(7:25) People will say to me, "There are people online who are obsessed with Inception or obsessed with Memento.”

They're asking me to comment on that, as if I thought it were weird or something, and I'm like, Well, I was obsessed with it for years. Genuinely obsessed with it. So it doesn't strike me as weird. . . I feel like I have managed to wrap them the up in it way I try to wrap myself up.

(8:30) The Futurist: The Life and Films of James Cameron by Rebecca Keegan and The Return of James Cameron, Box Office King by Zach Baron. (Founders #311)

(11:00) I don’t think of myself as an artist. I’m a craftsman. I don’t make a work of art; I make a movie. — George Lucas: A Life by Brian Jay Jones.

(15:30) Steven Spielberg: A Biography by Joseph McBride. (Founders #209)

(22:45) Nolan is relentlessly resourceful. He wants to spend as as little money as possible so he can maintain as much control over the project as possible.

(23:30) He makes his first movie on the weekends while he working a full-time job!

(29:30) The efficiency of filmmaking is for me a way of keeping control. The pressure of time, the pressure of money. Even though they feel like restrictions at the time, and you chafe against them, they're helping you make decisions. They really are. If I know that deadline is there, then my creative process ramps up exponentially.

(34:00) The result of making a billion dollar blockbuster: Suddenly his position at Warner Brothers went from solid to unassailable.

(37:00) Stories can add to your own thinking but you need your own foundation to add them to first.

(38:00) I know it's more fun when we're all together and we can do the thing together. That's why we keep it as a family business.

(39:00) Rolls-Royce: The Magic of a Name: The First Forty Years of Britain s Most Prestigious Company by Peter Pugh. (Founders #287)

(43:30) Every time a new feature or product was proposed, he decreed that the narrative should take the shape of a mock press release. The goal was to get employees to distill a pitch into its purest essence, to start from something the customer might see—the public announcement—and work backward. Bezos didn’t believe anyone could make a good decision about a feature or a product without knowing precisely how it would be communicated to the world. — The Everything Store: Jeff Bezos and the Age of Amazon by Brad Stone. (Founders #179)

(45:30) Once your children are born, you can never look at yourself through your own eyes anymore; you always look at yourself through their eyes.

(49:30) I often have terrible luck with the weather, but my philosophy is to shoot no matter what the weather is, always shooting no matter what weather, just keeping going, keeping going. Letting everybody on the crew and cast know we're really serious about doing that, no matter what the conditions are, so they're not looking out the window first thing and going, Oh, we will or won't shoot today.

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested, so my poor wallet suffers.” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

The Everything Store: Jeff Bezos and the Age of Amazon

Rolls-Royce: The Magic of a Name: The First Forty Years of Britain s Most Prestigious Company

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Modern Wisdom

Key Takeaways * The emotion that we do not want to feel is often the emotion that we invite in the exact way that we try to avoid it * The spiritual path for so many is just another way to say, ‘I am not good enough yet * You are not going to get to where you want to go by being a really sh*tty boss to yourself * Enjoyment is a state of mind * Letting go doesn’t happen by telling yourself to let go; letting go happens when it is ready * The desire to be special can only exist if you don’t know who you are * We make decisions on an emotional basis and we use logic to figure out how we will feel based on a decision * If you can’t say no, then you can’t find your “yes” * People don’t want you to be perfect; what they want is to feel connected with you * We know ourselves by comparative contrast; but when we feel joy, the contrast goes away * The “inner voice” is not necessarily bad; oftentimes though, it is irrational and incompetent * The key to self-improvement is understanding who you are * Instead of considering what is wrong in your life and how to fix it, consider what is right and how you can grow it

Read the full notes @ podcastnotes.org

Joe Hudson is a coach, entrepreneur and a podcast host.
We are often our own harshest critics. Everyone knows that it’s important to be kinder and more understanding to ourselves, yet this is a challenge. So what is a more reliable route to developing self-compassion, stopping negative self-talk and getting out of our own way?
Expect to learn what the real Matrix is, how to identify thoughts that might be holding you back, why feeling superior only works if you’re suppressing emotions, why people struggle so much to connect with their inner world, how to reduce negative self talk, where self discovery comes from and much more...
Sponsors:
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

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How to Take Over the World

Key Takeaways * Check out Ben’s website

Read the full notes @ podcastnotes.org

"Some people create with words or with music or with a brush and paints. I like to make something beautiful. When I run, I like to make people stop and say, ‘I’ve never seen anyone run like that before.’ It’s more than just a race, it’s style. It’s doing something better than anyone else."

Steve Prefontaine is one of the great legends of the running world. In this episode, we cover his remarkable story and talk about the strategies, tactics, and work habits that made him so effective.

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Writing, production, and sound editing by Ben Wilson with support from Michael Lackner.
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My First Million

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Episode 609: Sam Parr ( https://twitter.com/theSamParr ) and Shaan Puri ( https://twitter.com/ShaanVP ) break down the genius marketing tactics used by the brands you can’t get out of your brain–no matter how much you want to.

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Show Notes:
(0:00) The history of jingles (Bring them back!)
(11:07) Prediction: Polymarket is going to be massive
(21:25) The wisdom on the crowd phenomenon
(26:36) How gaming apps hunt for whales
(31:00) Corporate Slang That Doesn't Exist But Should

—
Links:
• DatPiff - https://www.datpiff.com/
• Polymarket - https://polymarket.com/

—
Check Out Shaan's Stuff:
Need to hire
? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

—
Check Out Sam's Stuff:
• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth
• Sam’s List - http://samslist.co/

My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

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Lenny's Podcast: Product | Growth | Career✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Mike Maples, Jr. is a legendary early-stage startup investor and a co-founder and partner at Floodgate. He’s made early bets on transformative companies like Twitter, Lyft, Twitch, Okta, Rappi, and Applied Intuition and is one of the pioneers of seed-stage investing as a category. He’s been on the Forbes Midas List eight times and enjoys sharing the lessons he’s learned from his years studying iconic companies. In his new book, Pattern Breakers: Why Some Start-Ups Change the Future, co-authored with Peter Ziebelman,he discusses what he’s found separates startups and founders that break through and change the world from those that don’t. After spending years reviewing the notes and decks from the thousands of startups he’s known over the past two decades, he’s uncovered three ways that breakthrough founders think and act differently. In our conversation, Mike talks about:

• The three elements of breakthrough startup ideas

• Why you need to both think and act differently

• How to avoid the “comparison trap” and “conformity trap”

• The importance of movements, storytelling, and healthy disagreeableness in startup success

• How to apply pattern-breaking principles within large companies

• Mike’s one piece of advice for founders

• Much more

Pre-order Mike’s book here and get a second signed copy for free. Limited copies are available, so order ASAP: patternbreakers.com/lenny.

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Find the transcript at: https://www.lennysnewsletter.com/p/how-to-find-a-great-startup-idea-mike-maples-jr

—

Where to find Mike Maples, Jr.:

• X: https://x.com/m2jr

• LinkedIn: https://www.linkedin.com/in/maples/

• Substack: https://greatness.substack.com/

• Website: https://www.floodgate.com/

—

Where to find Lenny:

• Newsletter: https://www.lennysnewsletter.com

• X: https://twitter.com/lennysan

• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/

—

In this episode, we cover:

(00:00) Mike’s background

(03:10) The inspiration behind Pattern Breakers

(08:09) Uncovering startup insights

(11:37) A quick summary of Pattern Breakers

(13:52) Coming up with an idea

(15:30) Inflections

(17:09) Examples of inflections

(28:10) Insights

(36:58) The power of surprises

(47:36) Founder-future fit

(55:33) Advice for aspiring founders

(56:41) Living in the future: valid opinions

(55:34) Case study: Maddie Hall and Living Carbon

(58:40) Identifying lighthouse customers

(01:00:53) The importance of desperation in customer needs

(01:03:57) Creating movements and storytelling

(01:24:22) The role of disagreeableness in startups

(01:34:42) Applying these principles within a company

(01:40:43) Lightning round

—

Referenced:

• Pattern Breakers: Why Some Start-Ups Change the Future: https://www.amazon.com/Pattern-Breakers-Start-Ups-Change-Future/dp/1541704355

• Justin.tv: https://en.wikipedia.org/wiki/Justin.tv

• Airbnb’s CEO says a $40 cereal box changed the course of the multibillion-dollar company: https://fortune.com/2023/04/19/airbnb-ceo-cereal-box-investors-changed-everything-billion-dollar-company/

• Brian Chesky’s new playbook: https://www.lennysnewsletter.com/p/brian-cheskys-contrarian-approach

• The Unconventional Exit: How Justin Kan Sold His First Startup on eBay: https://medium.datadriveninvestor.com/the-unconventional-exit-how-justin-kan-sold-his-first-startup-on-ebay-4d705afe1354

• Kyle Vogt on LinkedIn: https://www.linkedin.com/in/kylevogt/

• The State of Telehealth Before and After the COVID-19 Pandemic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035352/

• The Craigslist Killers: https://www.gq.com/story/craigslist-killers

• The social radar: Y Combinator’s secret weapon | Jessica Livingston (co-founder of Y Combinator, author, podcast host): https://www.lennysnewsletter.com/p/the-social-radar-jessica-livingston

• Michael Seibel on LinkedIn: https://www.linkedin.com/in/mwseibel/

• The Airbnb Story: How Three Ordinary Guys Disrupted an Industry, Made Billions ... and Created Plenty of Controversy: https://www.amazon.com/Airbnb-Story-Ordinary-Disrupted-Controversy/dp/0544952669

• Scott Cook: https://www.forbes.com/profile/scott-cook/

• Chegg: https://www.chegg.com/

• Aayush Phumbhra on LinkedIn: https://www.linkedin.com/in/aayush/

• Osman Rashid on LinkedIn: https://www.linkedin.com/in/osmanrashid/

• Okta: https://www.okta.com/

• The Man Who Makes the Future: Wired Icon Marc Andreessen: https://www.wired.com/2012/04/ff-andreessen/

• Peter Ludwig on LinkedIn: https://www.linkedin.com/in/peterwludwig/

• Qasar Younis on LinkedIn: https://www.linkedin.com/in/qasar/

• Paul Allen’s website: https://paulallen.com/

• Louis Pasteur quote: https://www.forbes.com/quotes/6145/

• What was Atrium and why did it fail? https://www.failory.com/cemetery/atrium

• Patrick Collison on LinkedIn: https://www.linkedin.com/in/patrickcollison/

• Drew Houston on LinkedIn: https://www.linkedin.com/in/drewhouston/

• William Gibson’s quote: https://www.goodreads.com/quotes/681-the-future-is-already-here-it-s-just-not-evenly

• Maddie Hall on LinkedIn: https://www.linkedin.com/in/maddie-hall-76293135/

• Living Carbon: https://www.livingcarbon.com

• Zenefits (now Trinet): https://connect.trinet.com/

• Sam Altman on X: https://x.com/sama

• Steve Wozniak on LinkedIn: https://www.linkedin.com/in/wozniaksteve/

• Horsley Bridge Partners: https://www.horsleybridge.com/

• David Swensen: https://en.wikipedia.org/wiki/David_F._Swensen

• Judith Elsea on LinkedIn: https://www.linkedin.com/in/judithelsea/

• 7 Powers: The Foundations of Business Strategy: https://www.amazon.com/7-Powers-Foundations-Business-Strategy/dp/0998116319

• Business strategy with Hamilton Helmer (author of 7 Powers): https://www.lennysnewsletter.com/p/business-strategy-with-hamilton-helmer

• Lyft’s Focus on Community and the Story Behind the Pink Mustache: https://techcrunch.com/2012/09/17/lyfts-focus-on-community-and-the-story-behind-the-pink-mustache/

• Logan Green on LinkedIn: https://www.linkedin.com/in/logangreen/

• John Zimmer on LinkedIn: https://www.linkedin.com/in/johnzimmer11/

• Storytelling with Nancy Duarte: How to craft compelling presentations and tell a story that sticks: https://www.lennysnewsletter.com/p/storytelling-with-nancy-duarte-how

• Steve Jobs Introducing the iPhone at MacWorld 2007: https://www.youtube.com/watch?v=x7qPAY9JqE4

• Jonathan Livingston Seagull: https://www.amazon.com/Jonathan-Livingston-Seagull-Richard-Bach/dp/0743278909

• The paths to power: How to grow your influence and advance your career | Jeffrey Pfeffer (author of 7 Rules of Power, professor at Stanford GSB): https://www.lennysnewsletter.com/p/the-paths-to-power-jeffrey-pfeffer

• Robin Roberts on LinkedIn: https://www.linkedin.com/in/robin-roberts-393a934b/

• Skunkworks: https://www.lockheedmartin.com/en-us/who-we-are/business-areas/aeronautics/skunkworks.html

• Vision, conviction, and hype: How to build 0 to 1 inside a company | Mihika Kapoor (Product at Figma): https://www.lennysnewsletter.com/p/vision-conviction-hype-mihika-kapoor

• Hard-won lessons building 0 to 1 inside Atlassian | Tanguy Crusson (Head of Jira Product Discovery): https://www.lennysnewsletter.com/p/building-0-to-1-inside-atlassian-tanguy-crusson

• Figma: https://www.figma.com/

• Atlassian: https://www.atlassian.com/

• Vinod Khosla: https://www.khoslaventures.com/team/vinod-khosla/

• Top Five Regrets of the Dying: A Life Transformed by the Dearly Departing: https://www.amazon.com/Top-Five-Regrets-Dying-Transformed-ebook/dp/B07KNRLY1L

• Chase, Chance, and Creativity: The Lucky Art of Novelty: https://www.amazon.com/Chase-Chance-Creativity-Lucky-Novelty/dp/0262511355

• Clay Christensen’s books: https://www.amazon.com/stores/Clayton-M.-Christensen/author/B000APPD3Y

• Resonate: Present Visual Stories That Transform: https://www.amazon.com/Resonate-Present-Stories-Transform-Audiences/dp/0470632011

• Ferrari on Prime: https://www.amazon.com/Ferrari-Adam-Driver/dp/B0CNDBN672

• Montblanc fountain pens: https://www.montblanc.com/en-us

—

Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.

—

Lenny may be an investor in the companies discussed.

Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

Resonate: Present Visual Stories that Transform Audiences

7 Powers: The Foundations of Business Strategy

Top Five Regrets of the Dying: A Life Transformed by the Dearly Departing

Chase, Chance, and Creativity: The Lucky Art of Novelty

The Airbnb Story: How Three Ordinary Guys Disrupted an Industry, Made Billions . . . and Created Plenty of Controversy

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How to Take Over the World

Key Takeaways * Check out Ben’s website

Read the full notes @ podcastnotes.org

"When I was a child, my mother said to me, If you are a soldier, you will become a general. If you are a monk, you will become the pope. Instead, I was a painter And became Picasso."

What made Picasso such a great artist? And what made him such a legend both in his own time, and since his death? On this episode, we explore Picasso's life, his art, his impact, and the strategies he used to take over the art world.

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Art of Manliness

Key Takeaways * Happiness is not about feeling good, but being good; it is not about pursuing immediate pleasure, but instead about pursuing long-term virtue * The Enlightenment profoundly influenced the Founding Fathers of the United States by shaping their ideas on government, individual rights, and democracy * The Founding Fathers’ keys to self-improvement + 1. Read great books + 2. Practice daily self-improvement + 3. Improve alongside others * The Founding Fathers believed that they needed to achieve harmony in their minds before they would be able to achieve harmony in the constitution of the state * Pythagoras keys to seeking perfection: mindfulness, discipline, and moderation * Perfect virtue is unattainable; the value is in the pursuit of it * Cicero believed true happiness is found through virtue and moral integrity; he argued that happiness comes from within, emphasizing self-sufficiency, wisdom, and rational thinking * “Happiness is the meaning and the purpose of life, the whole aim and end of human existence.” – Aristotle

Read the full notes @ podcastnotes.org

A lot of self-improvement advice and content feels empty. And there's a reason for that. It often offers routines and habits to practice, but doesn't offer a strong, overarching reason to practice them.

That's why the self-improvement advice of the Founding Fathers is particularly compelling. Though they were imperfect men, they had a clear why for trying to become better than they were. For the Founders, life was about the pursuit of happiness, and they equated happiness with excellence and virtue — a state that wasn't about feeling good, but being good. The Founders pursued happiness not only for the personal benefit in satisfaction and tranquility it conferred, but for the way the attainment of virtue would benefit society as a whole; they believed that political self-government required personal self-government.

Today on the show, Jeffrey Rosen, a professor of law, the president of the National Constitution Center, and the author of The Pursuit of Happiness, shares the book the Founders read that particularly influenced their idea of happiness as virtue and self-mastery. We talk about the schedules and routines the Founders kept, the self-examination practices they did to improve their character, and how they worked on their flaws, believing that, while moral perfection was ultimately an impossible goal to obtain, it was still something worth striving for.

Resources Related to the Podcast AoM's series on Benjamin Franklin's 13 Virtues * Ben Franklin Virtues Journal available in the AoM Store * AoM Article: Young Benjamin Franklin’s Plan of Conduct * AoM Article: Thomas Jefferson’s 10 Rules for Life * AoM Article: The Libraries of Famous Men — Thomas Jefferson’s Recommended Reading * AoM Article: The Best John Adams Quotes * AoM Article: George Washington’s Rules of Civility and Decent Behavior in Company and Conversation * AoM Podcast #366: Teach Yourself Like George Washington * AoM Article: The Spiritual Disciplines — Study and Self-Examination * Tusculan Disputations* by Marcus Tullius Cicero * The Golden Verses of Pythagoras

Connect With Jeffrey Rosen* The National Constitution Center website * We the People podcast * Jeffrey's faculty page * Jeffrey on X

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School of Greatness

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Have you bought your tickets to Summit of Greatness 2024 yet?! Get them before they sell out at lewishowes.com/tickets

Listen to PART 1 of Sadia and Matthew’s discussion.

Welcome back! Today, we dive into the second part of a fascinating and eye-opening conversation with two incredible relationship experts, Sadia Khan and Matthew Hussey. If you missed the first part, I highly recommend you go back and listen to it, as it lays the groundwork for what we’re discussing today. In this episode, we explore the reasons why people lead double lives, the root causes of cheating, and the importance of having honest and courageous conversations in our relationships. We also debate the roles of self-compassion and self-respect in building and maintaining healthy connections. Get ready for a lively and insightful discussion that will challenge your perspectives on love, trust, and commitment.

In this episode you will learn

The psychological reasons behind cheating and leading double lives.
The importance of honest communication in relationships.
How self-compassion and self-respect influence relationship dynamics.
Strategies for selecting a compatible partner.
The significance of addressing past traumas and wounds before entering a relationship.

For more information go to www.lewishowes.com/1638

For more Greatness text PODCAST to +1 (614) 350-3960

More SOG episodes from Sadia Khan and Matthew Hussey:

These Dating MYTHS Are DESTROYING Your Love Life (What A Healthy Partner REALLY Wants!) | Sadia Khan – https://link.chtbl.com/1533-pod

Matthew Hussey's Expert Tips for Attracting and Maintaining True Love – https://link.chtbl.com/1490-pod

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How to Take Over the World

Key Takeaways * Following your curiosity is the best approach for making scientific discoveries * Some of Ben Franklin’s favorite quotes: + “Early to bed and early to rise makes a man healthy, wealthy, and wise.” + “Three may keep a secret, if two of them are dead.” + “Lost time is never found again.” + “Love your enemies for they tell you your faults.” + “Fish and visitors stink in three days.” * Learn how to turn disadvantages and obstacles into advantages * Benjamin Franklin made a key edit to Thomas Jefferson’s draft of the Declaration of Independence regarding the phrase “self-evident” + This change was significant because it emphasized the idea that the truths stated in the Declaration—such as equality and unalienable rights—are universally and intuitively understood, not dependent on external validation * Work hard, stay curious, and be fun-loving

Read the full notes @ podcastnotes.org

Benjamin Franklin was one of the greatest scientists, writers, diplomats, and statesmen of all time. How does one man accomplish so much in one life?
Well, he was also the first self-help guru of all time. On this episode, we examine the life of Benjamin Franklin, and the tools he used to become the world's first self-made man.

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Sources:
The Autobiography of Benjamin Franklin
Benjamin Franklin: An American Life

Writing, research, and production by Ben Wilson
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Modern Wisdom

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Brian Klaas is a political scientist, a professor at University College London and an author.
Small, seemingly insignificant events can have profound effects on the world. But how much of our fate is truly determined by chance, and if chaos plays such a huge role, how much control do we actually have over anything?
Expect to learn the chance story of the atomic bomb's targeting, the difference between contingency and convergence, why our brains are so good at distorting reality, the link between Donald Trump's election and the dinosaurs, how a cigar changed the course of the American Revolution, why floorboards in New England are 23 inches wide and much more...
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

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How to Take Over the World

Key Takeaways * Check out Ben’s website

Read the full notes @ podcastnotes.org

How did George Washington shape the future of the United States of America as its first president? In this episode, we examine his presidency, his post-presidency, his death, and his legacy.

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Sources:
Washington: A Life by Ron Chernow
George Washington and the New Nation: 1783-1793
George Washington: Anguish and Farewell 1793-1799

Writing, research, and production by Ben Wilson
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Conversations with Tyler

Intro * One person’s freedom is another person’s unfreedom * Unanimity theorem, also known as the Stiglitz-Greenwald theorem, posits that in the presence of incomplete markets and imperfect information, the competitive equilibrium is generally not Pareto efficient * Sharecropping can create poor incentives for tenants to work hard or invest in land improvement because they only receive a fraction of the output, leading to lower agricultural productivity compared to other forms of land tenure * Cities can achieve optimal sizes by balancing the benefits of agglomeration economies (such as increased productivity and innovation due to proximity) against the costs (such as congestion and pollution) * Carefully designed tax policies and urban planning can help cities grow in a way that maximizes economic efficiency and equity * Markets cannot be perfectly efficient because if prices fully reflect all available information, there would be no incentive for traders to acquire information, leading to a paradox * Markets are not very good at pricing risk into the decision-making process * Credit availability of monetary policy is what matters – not the money supply or interest rate * Hierarchies are particularly problematic when the people the at the top of them are not good decision makers

Read the full notes @ podcastnotes.org

Nobel Prize-winning economist Joseph Stiglitz joined Tyler for a discussion that weaves through Joe’s career and key contributions, including what he learned from giving an 8-lecture in Japan, how being a debater influenced his intellectual development, why he tried to abolish fraternities at Amherst, how studying Kenyan sharecropping led to one of his most influential papers, what he thinks today of Georgism and the YIMBY movement, why he was too right-wing for Cambridge, why he left Gary, Indiana, his current views on high trading volumes and liquidity, the biggest difference between him and Paul Krugman, what working in Washington, DC taught him about hierarchies, what he’ll do next, and more.

Read a full transcript enhanced with helpful links, or watch the full video.

Recorded April 22nd, 2024.

Other ways to connect

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Email us: cowenconvos@mercatus.gmu.edu
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Founders✓Claim

Key Takeaways * Support David Senra and get access to the world’s most valuable notebook for founders

Read the full notes @ podcastnotes.org

What I learned from reading Sam Walton: The Inside Story of America's Richest Man by Vance Trimble.

Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast.

Get access to Founders Notes here.

Build relationships with other founders, investors, and executives at a Founders Event

(2:30) Sam Walton built his business on a very simple idea: Buy cheap. Sell low. Every day. With a smile.

(2:30) People confuse a simple idea with an ordinary person. Sam Walton was no ordinary person.

(4:30) Traits Sam Walton had his entire life: A sense of duty. Extreme discipline. Unbelievable levels of endurance.

(5:30) His dad taught him the secret to life was work, work, work.

(5:30) Sam felt the world was something he could conquer.

(6:30) The Great Depression was a big leveler of people. Sam chose to rise above it. He was determined to be a success.

(11:30) You can make a lot of different mistakes and still recover if you run an efficient operation. Or you can be brilliant and still go out of business if you’re too inefficient. — Sam Walton: Made In America by Sam Walton. (Founders #234)

(15:30) He was crazy about satisfying customers.

(17:30) The lawyer saw Sam clenching and unclenching his fists, staring at his hands. Sam straightened up. “No,” he said. “I’m not whipped. I found Newport, and I found the store. I can find another good town and another store. Just wait and see!”

(21:30) Sometimes hardship can enlighten and inspire. This was the case for Sam Walton as he put in hours and hours of driving Ozark mountain roads in the winter of 1950. But that same boredom and frustration triggered ideas that eventually brought him billions of dollars. (This is when he learns to fly small planes. Walmart never happens otherwise)

(33:30) At the start we were so amateurish and so far behind K Mart just ignored us. They let us stay out here, while we developed and learned our business. They gave us a 10 year period to grow.

(37:30) And so how dedicated was Sam to keeping costs low? Walmart is called that in part because fewer letters means cheaper signs on the outside of a store.

(42:30) Sam Walton is tough, loves a good fight, and protects his territory.

(43:30) His tactics later prompted them to describe Sam as a modern-day combination of Vince Lombardi (insisting on solid execution of the basics) and General George S. Patton. (A good plan, violently executed now, is better than a perfect plan next week.)

(43:30) Hardly a day has passed without Sam reminding an employee: "Remember Wal-Mart's Golden Rule: Number one, the customer Is always right; number two, if the customer isn't right, refer to rule number one.”

(46:30) The early days of Wal-Mart were like the early days of Disneyland: "You asked the question, What was your process like?' I kind of laugh because process is an organized way of doing things. I have to remind you, during the 'Walt Period' of designing Disneyland, we didn't have processes. We just did the work. Processes came later. All of these things had never been done before. Walt had gathered up all these people who had never designed a theme park, a Disneyland.

So we're in the same boat at one time, and we figure out what to do and how to do it on the fly as we go along with it and not even discuss plans, timing, or anything.

We just worked and Walt just walked around and had suggestions. — Disney's Land: Walt Disney and the Invention of the Amusement Park That Changed the World by Richard Snow. (Founders #347)

(1:04:30) Sam Walton said he took more ideas from Sol Price than any other person. —Sol Price: Retail Revolutionary by Robert Price. (Founders #304)

(1:07:30) Nothing in the world is cheaper than a good idea without any action behind it.

(1:07:30) Sam Walton: Made In America (Founders #234)

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

Disney's Land: Walt Disney and the Invention of the Amusement Park That Changed the World

Sol Price Retail Revolutionary & Social Innovator

Sam Walton: The Inside Story of America's Richest Man

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Founders✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

What I learned from reading How To Be Rich by J. Paul Getty.

Build relationships with other founders, investors, and executives at a Founders Event

"Learning from history is a form of leverage." — Charlie Munger.

Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand. You can search all my notes and highlights from every book I've ever read for the podcast.

Get access to Founders Notes here.

You can also ask SAGE (the Founders Notes AI assistant) any question and SAGE will read all my notes, highlights, and every transcript from every episode for you.

A few questions I've asked SAGE recently:

What are the most important leadership lessons from history's greatest entrepreneurs?

Can you give me a summary of Warren Buffett's best ideas? (Substitute any founder covered on the podcast and you'll get a comprehensive and easy to read summary of their ideas)

How did Edwin Land find new employees to hire? Any unusual sources to find talent?

What are some strategies that Cornelius Vanderbilt used against his competitors?

Get access to Founders Notes here.

(2:00) My father was a self-made man who had known extreme poverty in his youth and had a practically limitless capacity for hard work.

(6:00) I acted as my own geologist, legal advisor, drilling superintendent, explosives expert, roughneck and roustabout.

(8:00) Michael Jordan: The Life by Roland Lazenby. (Founders #212)

(12:00) Control as much of your business as possible. You don’t want to have to worry about what is going on in the other guy’s shop.

(20:00) Optimism is a moral duty. Pessimism aborts opportunity.

(21:00) I studied the lives of great men and women. And I found that the men and women who got to the top were those who did the jobs they had in hand, with everything they had of energy and enthusiasm and hard work.

(22:00) 98 percent of our attention was devoted to the task at hand. We are believers in Carlyle's Prescription, that the job a man is to do is the job at hand and not see what lies dimly in the distance. — Charlie Munger

(27:00) Entrepreneurs want to create their own security.

(34:00) Example is the best means to instruct or inspire others.

(37:00) Long orders, which require much time to prepare, to read and to understand are the enemies of speed. Napoleon could issue orders of few sentences which clearly expressed his intentions and required little time to issue and to understand.

(38:00) A Few Lessons for Investors and Managers From Warren Buffett by Warren Buffett and Peter Bevelin. (Founders #202)

(41:00) Two principles he repeats:

Be where the work is happening.

Get rid of bureaucracy.

(43:00) Years ago, businessmen automatically kept administrative overhead to an absolute minimum. The present day trend is in exactly the opposite direction. The modern business mania is to build greater and ever greater paper shuffling empires.

(44:00) Les Schwab Pride In Performance: Keep It Going!by Les Schwab (Founders #330)

(46:00) The primary function of management is to obtain results through people.

(50:00) the truly great leader views reverses, calmly and coolly. He is fully aware that they are bound to occur occasionally and he refuses to be unnerved by them.

(51:00) There is always something wrong everywhere.

(51:00) Don't interrupt the compounding. It’s all about the long term. You should keep a fortress of cash, reinvest in your business, and use debt sparingly. Doing so will help you survive to reap the long-term benefits of your business.

(54:00) You’ll go much farther if you stop trying to look and act and think like everyone else.

(55:00) The line that divides majority opinion from mass hysteria is often so fine as to be virtually invisible.

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

A Few Lessons for Investors and Managers From Warren Buffett

Les Schwab Pride in Performance: Keep It Going

View Details

Modern Wisdom

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

George Mack is a writer, marketer and an entrepreneur.
George is one of my favourite writers and probably delivers the highest insights-per-minute of anyone on Twitter. Today we get to go through some of my favourite ideas from him over the last few months on human nature, tribalism, happiness and politics.
Expect to learn what the Busy Trap is and how to avoid it, the biggest differences between the US and the UK, the contrarian argument for why money doesn’t buy happiness, why strategic ignorance is so important, George’s favourite story about Charlie Munger, the lessons we both learned celebrating George’s 30th birthday in Miami and much more...
Sponsors:
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Extra Stuff:
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

Get In Touch:
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Aarthi and Sriram's Good Time Show✓Claim

Show Notes:

(0:00) Audio issue

(0:51) Introduction

(3:40) Deals are long-term relationships

(6:02) Facebook-WhatsApp acquisition story

(12:04) The most important part of deal-making

(16:44) Don’t come off as desperate

(19:35) Maintaining momentum during a deal

(25:53) Know everything about the person you’re dealing with

(33:37) How we closed our London home

(37:54) Mistakes we often see

(44:40) Managing emotions while deal-making

(50:19) What to do if the deal falls through

Other episodes you might enjoy:

EP 76 - How To Fix Legal Immigration In America

EP 74 - How To Fix Google's WOKE AI Disaster

EP 63 - Lessons From Networking In Silicon Valley

EP 59 - Why We Moved to London, The Elon Musk Book, Should You Get An MBA

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Artificial Intelligence Podcast

Key Takeaways * Hardship will show you who your real friends are; don’t eat with people that you wouldn’t starve with * On evolving: You do something for awhile, you do it at the highest possible level for you, and then at some point you pivot and start supporting the young talent that eventually emerges * For certain individuals, high-THC cannabis can induce psychosis * The Jungian shadow is the unconscious part of the personality that holds repressed weaknesses, desires, and instincts + Integrating the shadow is essential for personal growth, as it involves acknowledging these hidden aspects to achieve a more balanced and complete self-awareness * Being in a state of silence – either while sitting or walking – can help you to discover a better understanding of yourself and allow you to really tap into your unique gifts * Nicotine is an interesting compound; it will raise blood pressure, and it is probably not safe for everybody * While Andrew does not recommend for people to use nicotine frequently, or at all – especially young people who are 25-years-old or younger – he will allow himself two pieces of Nicorette total, per week * Just because a compound is a pharmaceutical does not mean that it is “bad” * On fostering meaningful relationships: Obviously pick the right partner, but also do the work on yourself

Read the full notes @ podcastnotes.org

Andrew Huberman is a neuroscientist at Stanford and host of the Huberman Lab Podcast. Please support this podcast by checking out our sponsors:
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Transcript: https://lexfridman.com/andrew-huberman-5-transcript

EPISODE LINKS:
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Andrew's book: https://hubermanlab.com/protocols-book

PODCAST INFO:
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OUTLINE:
Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) - Introduction
(10:24) - Quitting and evolving
(17:22) - How to focus and think deeply
(19:56) - Cannabis drama
(30:08) - Jungian shadow
(40:35) - Supplements
(43:38) - Nicotine
(48:01) - Caffeine
(49:48) - Math gaffe
(1:06:50) - 2024 presidential elections
(1:13:47) - Great white sharks
(1:22:32) - Ayahuasca & psychedelics
(1:37:33) - Relationships
(1:45:08) - Productivity
(1:53:58) - Friendship

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CryptoThe Investor's Podcast (TIP)

Key Takeaways * The year 1971 marked the beginning of the era in which the federal government became interested in altering the food supply * Nixon and other government leaders knew that food prices would extensively rise following The Nixon Shock + This realization kicked off a 55-year gaslighting campaign to change the trajectory of the food supply so that people would overlook the rising cost of nutrient-dense foods * If a person eats a diet of Doritos and grains, then he probably doesn’t realize monetary inflation; but if he eats a diet of ribeye steaks, monetary inflation is much more apparent to him * Nutrient-dense foods, such as red meat, are increasingly becoming a food of the upper classes * Government-influenced dietary guidelines serve the aggrandizement of the political leaders more so than they favor the betterment of the people * Once seed oils were no longer viable for industrial applications, large corporations began to market those seed oils as food; this was the first time that Americans began to consume things that were not food * When President Lyndon Johnson was going up for re-election, the cost of eggs was skyrocketing in price; he instructed his surgeon general to write a phony press release saying that eggs were unhealthy so that demand for eggs would decrease + To this day, people still believe the “eggs are bad for you” press release was motivated by political purposes, and not supported by any scientific evidence * The implementation of a hard currency would help to solve the modern crisis in food because it would help to undermine the incentive for the federal government to obfuscate the food supply * A hard currency removes the ability for governments to print money, therefore reducing the government’s need to gaslight dietary guidelines * “If you’re not healthy, you’re not free. Self-autonomy begins with personal health.” – Matthew Lysiak

Read the full notes @ podcastnotes.org

In this episode of the Bitcoin Fundamentals Podcast, investigative journalist Matthew Lysiak discusses his latest book on fiat food policies, influential figures like Ancel Keys, corporate interests, and the impact of inflation on health.

IN THIS EPISODE YOU’LL LEARN:
00:00 - Intro
02:22 - The history and impact of fiat food policies.
10:11 - The role of influential figures like Ancel Keys and John Harvey Kellogg.
25:11 - Insights into nutrient density and its importance.
26:21 - How to accurately measure the CPI bucket considering nutrient dense food prices.
29:02 - How corporate interests have shaped national food policies since 1884.
40:30 - The monetary and nutrition shifts of the 1970s.
52:03 - The real cost of inflation on financial, physical, and mental health.
56:21 - How Bitcoin can change the current food and health landscape.

Disclaimer: Slight discrepancies in the timestamps may occur due to podcast platform differences.

BOOKS AND RESOURCES

Matthew’s Book: Fiat Food.

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How to Take Over the World

George Washington is one of the most celebrated and beloved leaders of all time. What was it about Washington that made him such an effective leader? On this episode, we explore the making of George Washington: How he rose from relatively mundane origins to become the head of the American revolution.

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Sources:
Washington: A Life by Ron Chernow
George Washington in the American Revolution (1775-1783)

Writing, research, and production by Ben Wilson
Research assistance by Camille Doom
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Modern Wisdom

Key Takeaways * “The best diet for you – the individual – is the one that you can adhere to consistently.” – Dr Layne Norton * The main reason why diets fail is because people view them as a “diet” instead of a lifestyle change * People who have lost weight and successfully kept it off say that they had to form a new identity; they had to become someone else * Being successful and having fun are not mutually exclusive; just because you give yourself credit does not mean that you cannot strive for more * People who believe that they need excellent form on exercises to not get injured are actually more likely to get injured than people who think their bodies are strong and resilient * Weight loss requires some form of restriction – whether that is calorie restriction, dietary restriction, time restriction, or some variation of those three * If you look at the amount of lean mass that people lose while on Ozempic or GLP-1, it is very similar to the amount of lean mass that people lose when they just do the diet with no resistance training or exercise * Exercise sensitives your brain to satiety signals * Any diet that gets people to eat less processed foods and more satiating foods is going to be a diet that is better than the Standard American Diet * A recent meta-analysis showed that for every 10-gram increase in dietary fiber, there was a corresponding decrease in the relative risk of mortality, cancer, and cardiovascular disease * On a high-carb low-fat diet, you will not burn much fat, but you also do not store much fat; on a low-carb, high-fat diet, you are burning a lot of fat, but you are also storing a lot of fat * A little exercise can go a long way: Four minutes of vigorous exercise per day has been shown to decrease the risk of cancer incidents by 20% * If you are trying to lose weight, stop snacking! * In America, the average amount of physical activity is less than 20 minutes per day and the average caloric intake is 3500 calories per day – and we’re worried about seed oils and artificial sweeteners * Dr Layne Norton’s Mt. Rushmore of supplements: Creatine monohydrate (5-10g per day), Caffeine (the original nootropic and performance enhancer), and Whey protein * Tier 2 supplement list: Rhodiola rosea, Beta-alanine, Citrulline malate, ginseng, ashwagandha, fish oil, and melatonin

Read the full notes @ podcastnotes.org

Layne Norton is a Doctor of Nutritional Science, a powerlifter and an author.
Choosing the right diet and training plan for health can be complicated. Science offers one view, while your trainer suggests another. Fortunately, Layne provides all the expertise you need to find the best diets, foods, and lifestyle for you to build the healthiest and best version of yourself.
Expect to learn why people keep failing at their diets, if there is a best diet for overall health and wellness, Laynes thoughts on the new Ozempic craze, if the Carnivore diet is actually healthy for you, the top health foods you should be eating more of, how bad soy is for your health or if the hype is overblown, and much more...
Sponsors:
See discounts for all the products I use and recommend: https://chriswillx.com/deals
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

Get In Touch:
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Email: https://chriswillx.com/contact
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Art of Manliness

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

As compared to mothers, fathers are sometimes thought of as a secondary, almost superfluous, parent.

But my guest says that fathers actually saved the human race, and continue to do so today.

Anna Machin is an evolutionary anthropologist, a pioneer of fatherhood science, and the author of Life Of Dad. Today on the show, we talk about the role of fathers in human history and how their main role continues to be teaching kids the skills they need to take risks, become independent, and navigate the world beyond their family. We also talk about the physiological changes that happen when a man becomes a father and how dads are just as biologically primed as mothers to parent. In the second half of our conversation, we talk about the experience of being a dad. Anna shares how long it typically takes a man to bond with a baby and transition into the role of fatherhood, how roughhousing is key in building that bond as well as developing your child's resilience, and how your personality and background will affect your parenting. We end our conversation with the difference in how the relationship between Mom and Dad affects how they parent, and the implications of that for building a strong family.

Resources Related to the Podcast* AoM Article: The Importance of Fathers (According to Science) * AoM Article: A Man’s Guide to Pregnancy — Getting Ready for the Baby Bomb * AoM Article: A Man’s Guide to Pregnancy — Your Progeny Enters the World * AoM Article:New Dad Survival Guide — The Mindset * AoM Article: New Dad Survival Guide — The Skillset * AoM Podcast #119: Why Fathers Matter * AoM Article: You Don’t Have to Be Your Dad — How to Become Your Family’s Transitional Character

Connect With Anna Machin* Anna's website * Anna on X * Anna on IG

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Knowledge Project

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Succeeding in both life and business is very difficult. The skills needed to scale a company often clash with those required to cultivate a thriving home life. Yet, Brent Beshore seems to have cracked the code—or at least he's actively working on it. In this conversation, he spills his secrets on excelling in both arenas.

This episode is split into two parts: the first 45 minutes covers life and how to be a better person. Brent opens up about the evolution of his marriage, physical health, and inner life.

The rest of the episode focuses on business. Shane and Beshore discuss private equity, how to hire (and when to fire) CEOs, incentives, why debt isn’t a good thing in an unpredictable world, stewardship versus ownership, and why personality tests are so important for a functional organization.
After beginning his career as an entrepreneur, Brent Beshore founded Permanent Equity in 2007 and leads the firm as CEO. He works with investors and operators to evaluate new investment opportunities.

Watch the episode on YouTube: https://www.youtube.com/c/theknowledgeproject/videos

Newsletter - I share timeless insights and ideas you can use at work and home. Join over 600k others every Sunday and subscribe to Brain Food. Try it: https://fs.blog/newsletter/

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(00:00) Intro

(05:08) Why Brent examined his life

(09:44) How Brent "fixed" his relationships

(20:04) How helping hurts

(32:13) How Brent was subtly controlling relationships

(40:36) Why Brent stopped drinking (mostly)

(50:29) How to run a business with love yet competitively

(01:00:34) Win-win relationships

(01:05:34) On debt

(01:19:28) On incentives

(01:29:08) How to hire and fire CEOs

(01:34:18) What most people miss about hiring

(01:44:19) Brent's playbook for taking over a company

(01:51:20) On projections

(01:55:52) Revisiting investments

(01:58:44) How "hands-off" is Brent?

(02:08:34) Where people go wrong in private equity

(02:14:07) On success

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Infinite Loops

Key Takeaways * “Uncertainty is the only certainty.” – John Paulos * People use terms like millions, billions, and trillions as if they are the same thing; when in reality, these are vastly different amounts! * “We live in a probabilistic world, and yet we remain deterministic thinkers.” – Jim O’Shaughnessy * The Law of Large Numbers is a fundamental principle in probability and statistics that states that as the size of a sample increases, the average of the sample becomes closer to the expected value * Apophenia: The phenomenon of seeing patterns where none exist as a form of cognitive bias or psychological tendency * Humans are excellent pattern-recognition machines; but sometimes, we wrongly attribute patterns to random data that can lead us astray * The human operating system is more driven by the emotional centers of the brain than the rational centers of the brain * There is a tension between objective likelihood (probability) and subjective belief or reasonableness (plausibility) * The Prisoner’s Dilemma is a scenario in game theory where two individuals acting in their self-interest end up with a worse outcome than if they had cooperated * Cognitive foibles such as confirmation bias, the anchoring effect, and negativity bias should be taught in mathematical courses * Dunning-Kruger Effect: The phenomenon where people with low ability at a task overestimate their ability, while those with high ability underestimate their competence * The concept of “nudging” involves subtly influencing people’s decisions by altering the presentation of choices without restricting options or significantly changing incentives * It is wise to develop a particular skepticism and wariness about the uncertainties of life

Read the full notes @ podcastnotes.org

Professor, Mathematician and Writer John A. Paulos joins the show to discuss math education, the power of puzzles, cognitive biases, and MUCH more!

Important Links:

John’s Website
John’s Twitter

Show Notes:

Why Do People Hate Math?
The Power of Posing Problems with Counterintuitive or Shocking Results
Using Everyday Examples to Understand Math Concepts
Systems Designed to Take Advantage of Innumeracy
People’s Ignorance of Randomness and Random Samples
The Strange Power of Anchoring Bias
Tradeoffs between Probability and Plausibility
The Prisoner’s Dilemma & Math Anxiety
Improving the Monty Hall Problem
Designing an Ideal Intro Math Course
The Big Brother Aspect of Nudging
John as Emperor of the World
MORE!

Books Mentioned:

Innumeracy - Mathematical Illiteracy and Its Consequences; by J.A. Paulos
A Mathematician Plays the Stock Market; by J.A. Paulos
A Mathematician Reads the Newspaper; by J.A. Paulos
Statistics; by D.A. Freedman, R. Pisani, and R.A. Purves
Thinking Fast and Slow; by Daniel Kahneman

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Invest Like the Best

Key Takeaways * Leaders must “work up” through osmosis; do not assume that your messages are distributed throughout the company without intention and effort * Most organizations tell the leadership team what they want to hear; this can prevent the executive team from actually understanding what is happening within their own company * The most effective ways to communicate are through stories, celebration, and recognition * Great leaders are high energy and are willing to tolerate disagreement * As a leader, people want a piece of you; you must think about how you show them that you are invested in their success * Leaders must be open to understanding what they do not know * Every employee should understand what their CEO wants from them * “To be a successful leader, you got to allocate capital right and allocate human resources right. If you do those two things right, everything else will fall into place. If you do them wrong – you can do everything else right, you can have great culture, all the rest – it’s not going to matter.” – Frank Blake * Vision is powerful, but execution is even more so powerful

Read the full notes @ podcastnotes.org

My guest today is Frank Blake. Frank is the former chairman and CEO of Home Depot. I recently interviewed Home Depot co-founder Ken Langone and became fascinated by the business’s impressive lineup of leaders through the decades. Frank led the company from 2007 to 2014 and shares how he carried on the legacy of Ken and the others, upholding their culture of an inverted hierarchy and producing seven consecutive years of growth for the largest home improvement retailer in America. We discuss his hyper focus on solving their customer’s problems before their own, investing time into the employee experience, and his intentionality with how he is perceived as a leader. Please enjoy this discussion with Frank Blake.

Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, where we're changing the game in investment research. Step away from outdated, inefficient methods and into the future with our platform, proudly hosting over 100,000 transcripts – with over 25,000 transcripts added just this year alone. Our platform grows eight times faster and adds twice as much monthly content as our competitors, putting us at the forefront of the industry. Plus, with 75% of private market transcripts available exclusively on Tegus, we offer insights you simply can't find elsewhere. See the difference a vast, quality-driven transcript library makes. Unlock your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).
Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:04:37) The Inverted Pyramid Leadership Model
(00:08:38) Communication and Listening in Leadership
(00:15:19) Lessons from Legacies of Great Home Depot Leaders
(00:27:02) Frank’s Personal Leadership Journey
(00:33:32) Reagan's Leadership Style and Influence
(00:37:26) Key Responsibilities of a CEO
(00:40:27) Delta's Leadership During COVID-19
(00:46:45) Financial Strategies in Asset-Intensive Industries
(00:47:27) Home Depot's Strategic Shift
(00:53:33) Competitive Dynamics with Lowe's
(00:55:36) Building an Effective Board
(00:58:16) The Impact of Home Depot on Employees' Lives
(01:01:52) The Kindest Thing Anyone Has Ever Done for Frank

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Invest Like the Best

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

My guest today is Adam Sandow. Adam is the chairman and CEO of SANDOW Companies and the executive chairman and founder of Material Bank. He has built an entire ecosystem of businesses and brands that have brought him into the game of media, materials, and beyond. From creating the beauty product subscription model to getting magazines in the hands of billionaires to transforming the design industry with overnight access to samples, when Adam starts a business he writes his own rulebook. We discuss the founding stories of his most interesting companies, his obsession with targeting pain points, and his philosophies for when to go all in and betting on himself. Please enjoy this great discussion with Adam Sandow.

Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, where we're changing the game in investment research. Step away from outdated, inefficient methods and into the future with our platform, proudly hosting over 100,000 transcripts – with over 25,000 transcripts added just this year alone. Our platform grows eight times faster and adds twice as much monthly content as our competitors, putting us at the forefront of the industry. Plus, with 75% of private market transcripts available exclusively on Tegus, we offer insights you simply can't find elsewhere. See the difference a vast, quality-driven transcript library makes. Unlock your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).
Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:04:12) Building a Media Empire
(00:06:01) The Birth of the Beauty Subscription Model
(00:09:56) Revolutionizing Magazine Circulation
(00:14:46) The Contrarian Approach to Media
(00:16:08) The Origin of MediaJet
(00:18:35) The Future of Print and Digital Media
(00:27:25) The Genesis of Material Bank
(00:35:23) Building a Compelling Model for Manufacturers
(00:37:26) Innovative Logistics and Partnership with FedEx
(00:40:32) The Importance of High-Quality Content
(00:43:49) Building and Buying Media Properties
(00:46:01) Creating Unique Value Propositions
(00:54:22) The Role of Print in the Digital Age
(00:58:41) Nurturing an Ecosystem of Businesses
(01:03:37) The Kindest Thing Anyone Has Ever Done for Adam

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Deep Questions with Cal Newport✓Claim

We talk a lot on this show about how to organize and execute your work, but not enough about where to do it. In this episode, Cal explores the theory and practice of “adventure working,” in which you escape to novel and inspiring locations to tackle your most demanding and interesting cognitive efforts. He then answers reader questions about habits and rituals, before ending with a critical look at a famous football club’s distressing embrace of pseudo-productivity.

Below are the questions covered in today's episode (with their timestamps). Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo

Video from today’s episode: youtube.com/calnewportmedia

Deep Dive: Re-Enchanting Work [5:39]

What are Cal’s health habits? [31:12]
What’s the difference between discipline and rituals? [34:08]
How does Cal read so much? [37:37]
What are Cal’s writing-related rituals? [40:44]
Should I go slow in my job hunting? [45:05]
CALL: Working at a natural pace as a teacher [49:47]
CALL: How to navigate the “pull system” [54:31]

CASE STUDY: Organizing files in a household [1:00:57]

CAL REACTS: Manchester’s United’s Pseudo-Productivity [1:11:13]

Links:

Buy Cal’s latest book, “Slow Productivity” at calnewport.com/slow
Get a signed copy of Cal’s “Slow Productivity” at peoplesbooktakoma.com/event/cal-newport/
calnewport.com/adventure-studying-an-unconventional-new-approach-to-exam-preperation/
calnewport.com/bonus-post-an-adventure-studying-case-study/
instagram.com/p/B1y5dV3HSC9/?igshid=1r2acwbmfztew
apcc.org/pond-stories-mary-olivers-blackwater-pond-provincetown/
scottishfield.co.uk/scotland-travel/the-black-heart-of-scots-crime-writer-ian-rankin/
calnewport.com/the-power-of-the-outdoor-office/
calnewport.com/deep-habits-my-office-in-the-woods/
theguardian.com/football/article/2024/may/08/sir-jim-ratcliffe-manchester-united-remote-work-ban-email-traffic
theatlantic.com/ideas/archive/2024/02/hybrid-work-attention-productivity/677598/

Thanks to our Sponsors:

shopify.com/deep
blinkist.com/deep
listening.com/deep
drinklmnt.com/deep

Thanks to Jesse Miller for production, Jay Kerstens for the intro music, Kieron Rees for slow productivity music, and Mark Miles for mastering.

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Founders✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

What I learned from reading about Hans Wilsdorf and the founding of Rolex.

Build relationships at the Founders Conference on July 29th-July 31st in Scotts Valley, California

"Learning from history is a form of leverage." — Charlie Munger. Founders Notes gives you the superpower to learn from history's greatest entrepreneurs on demand.

Get access to Founders Notes here.

You can search all my notes and highlights from every book I've ever read for the podcast.

You can also ask SAGE any question and SAGE will read all my notes, highlights, and every transcript from every episode for you.

A few questions I've asked SAGE recently:

What are the most important leadership lessons from history's greatest entrepreneurs?

Can you give me a summary of Warren Buffett's best ideas? (Substitute any founder covered on the podcast and you'll get a comprehensive and easy to read summary of their ideas)

How did Edwin Land find new employees to hire? Any unusual sources to find talent?

What are some strategies that Cornelius Vanderbilt used against his competitors?

Get access to Founders Notes here.

(0:01) At the age of twelve I was an orphan.

(1:00) My uncles made me become self-reliant very early in life. Looking back, I believe that it is to this, that much of my success is due.

(9:00)The idea of wearing a watch on one's wrist was thought to be contrary to the conception of masculinity.

(10:00) Prior to World War 1 wristwatches for men did not exist.

(11:00) Business is problems. The best companies are just effective problem solving machines.

(12:00) My personal opinion is that pocket watches will almost completely disappear and that wrist watches will replace them definitively! I am not mistaken in this opinion and you will see that I am right." —Hans Wilsdorf, 1914

(14:00) The highest order bit is belief: I had very early realized the manifold possibilities of the wristlet watch and, feeling sure that they would materialize in time, I resolutely went on my way. Rolex was thus able to get several years ahead of other watch manufacturers who persisted in clinging to the pocket watch as their chief product.

(16:00) Clearly, the companies for whom the economics of twenty-four-hour news would have made the most sense were the Big Three broadcasters. They already had most of what was needed— studios, bureaus, reporters, anchors almost everything but a belief in cable. — Ted Turner's Autobiography (Founders #327)

(20:00) Business Breakdowns #65 Rolex: Timeless Excellence

(27:00) Rolex was effectively the first watch brand to have real marketing dollars put behind a watch. Rolex did this in a concentrated way and they've continued to do it in a way that is simply just unmatched by others in their industry.

(28:00) It's tempting during recession to cut back on consumer advertising. At the start of each of the last three recessions, the growth of spending on such advertising had slowed by an average of 27 percent. But consumer studies of those recessions had showed that companies that didn't cut their ads had, in the recovery, captured the most market share. So we didn't cut our ad budget. In fact, we raised it to gain brand recognition, which continued advertising sustains. — Four Seasons: The Story of a Business Philosophy by Isadore Sharp. (Founders #184)

(32:00) Social proof is a form of leverage. — Poor Charlie's Almanack: The Wit and Wisdom of Charlie Munger. (Founders #329)

(34:00) What really matters is Hans understood the opportunity better than anybody else, and invested heavily in developing the technology to bring his ideas to fruition.

(35:00) On keeping the main thing the main thing for decades: In developing and extending my business, I have always had certain aims in mind, a course from which I never deviated.

(41:00) Rolex wanted to only be associated with the best. They ran an ad with the headline: Men who guide the destinies of the world, where Rolex watches.

(43:00) Opportunity creates more opportunites. The Oyster unlocked the opportunity for the Perpetual.

(44:00) The easier you make something for the customer, the larger the market gets: “My vision was to create the first fully packaged computer. We were no longer aiming for the handful of hobbyists who liked to assemble their own computers, who knew how to buy transformers and keyboards. For every one of them there were a thousand people who would want the machine to be ready to run.” — Steve Jobs

(48:00) More sources:

Rolex Jubilee: Vade Mecum by Hans Wilsdorf

Rolex Magazine: The Hans Wilsdorf Years

Hodinkee: Inside the Manufacture. Going Where Few Have Gone Before -- Inside All Four Rolex Manufacturing Facilities

Vintage Watchstraps Blog: Hans Wilsdorf and Rolex

Business Breakdowns #65 Rolex: Timeless Excellence

Luxury Strategy: Break the Rules of Marketing to Build Luxury Brands by Jean Noel Kapferer and Vincent Bastien

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

Poor Charlie’s Almanack: The Essential Wit and Wisdom of Charles T. Munger

The Luxury Strategy: Break the Rules of Marketing to Build Luxury Brands

Four Seasons: The Story of a Business Philosophy

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Tetragrammaton with Rick Rubin✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Robert Downey Jr. is an actor and producer whose critically acclaimed performance as Lewis Strauss in Christopher Nolan's Oppenheimer earned him an Academy Award, a Golden Globe, and a BAFTA Award. His newest project, The Sympathizer, an HBO miniseries based on the 2015 Pulitzer Prize-winning novel of the same name, has Downey Jr. taking on multiple roles simultaneously.

Born into a family of filmmakers, Downey Jr. began acting as a child actor in his father's independent films, then entered mainstream Hollywood in the 1980s. His portrayal of the legendary Charlie Chaplin in the 1992 biopic Chaplin earned him an Academy Award nomination for Best Actor. After a period of personal struggles with substance abuse, Downey conquered his addiction, dedicated himself to sobriety, and made a remarkable professional resurgence. His starring roles as Tony Stark/Iron Man in the Marvel Cinematic Universe, in the action-adventure Sherlock Holmes, and in the action comedy Tropic Thunder catapulted him to global stardom. To date, Downey has appeared in over 70 movies, which have grossed over $14 billion, making Downey one of the highest-grossing actors of all time.

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Founders✓Claim

Key Takeaways * Business is sales; you are always selling * A person can have the greatest idea in the world, but if that person cannot convince enough other people about it, then it doesn’t matter * Sell the improvement that your products make and sell the better future that your customers will receive if they use your product * Advertising must promise a benefit to the customer * Repetition is persuasive * Entrepreneurs must learn how to tell a story about their business because that is how money works; money flows as a function of the story * Start your presentation with the problem; do not start with the product * Most business communicators lose sight of the fact that their audiences want to be informed and entertained * Identify what you are most passionate about, and then share that belief with your audience

Read the full notes @ podcastnotes.org

What I learned from reading The Presentation Secrets of Steve Jobs: How to Be Insanely Great in Front of Any Audience by Carmine Gallo

Come build relationships at the Founders Conference on July 29th-July 31st in Scotts Valley, California

Learning from history is a form of leverage. —Charlie Munger. Founders Notes gives you the super power to learn from history's greatest entrepreneurs on demand.

Get access to the World’s Most Valuable Notebook for Founders

You can search all my notes and highlights from every book I've ever read for the podcast.

You can also ask SAGE any question and SAGE will read all my notes, highlights, and every transcript from every episode for you.

A few questions I've asked SAGE recently:

What are the most important leadership lessons from history's greatest entrepreneurs?

Can you give me a summary of Warren Buffett's best ideas? (Substitute any founder covered on the podcast and you'll get a comprehensive and easy to read summary of their ideas)

How did Edwin Land find new employees to hire? Any unusual sources to find talent?

What are some strategies that Cornelius Vanderbilt used against his competitors?

Get access to Founders Notes here.

If you want me to speak at your company go here.

(1:00) You've got to start with the customer experience and work back toward the technology—not the other way around. —Steve Jobs in 1997

(6:00) Why should I care = What does this do for me?

(6:00) The Match King: Ivar Kreuger, The Financial Genius Behind a Century of Wall Street Scandals by Frank Partnoy. (Founders #348)

(7:00) Easy to understand, easy to spread.

(8:00) An American Saga: Juan Trippe and His Pan Am Empire by Robert Daley

(8:00) The Fish That Ate the Whale: The Life and Times of America's Banana King by Rich Cohen. (Founders #255)

(9:00) love how crystal clear this value proposition is. Instead of 3 days driving on dangerous road, it’s 1.5 hours by air. That’s a 48x improvement in time savings. This allows the company to work so much faster. The best B2B companies save businesses time.

(10:00) Great Advertising Founders Episodes:

Albert Lasker (Founders #206)

Claude Hopkins (Founders #170 and #207)

David Ogilvy (Founders #82, 89, 169, 189, 306, 343)

(12:00) Advertising which promises no benefit to the consumer does not sell, yet the majority of campaigns contain no promise whatever. (That is the most important sentence in this book. Read it again.) — Ogilvy on Advertising

(13:00) Repeat, repeat, repeat. Human nature has a flaw. We forget that we forget.

(19:00) Start with the problem. Do not start talking about your product before you describe the problem your product solves.

(23:00) The Invisible Billionaire: Daniel Ludwig by Jerry Shields. (Founders #292)

(27:00) Being so well known has advantages of scale—what you might call an informational advantage.

Psychologists use the term social proof. We are all influenced-subconsciously and, to some extent, consciously-by what we see others do and approve.

Therefore, if everybody's buying something, we think it's better.

We don't like to be the one guy who's out of step.

The social proof phenomenon, which comes right out of psychology, gives huge advantages to scale.

— the NEW Poor Charlie's Almanack: The Wit and Wisdom of Charlie Munger (Founders #329)

(29:00) Marketing is theatre.

(32:00) Belief is irresistible. — Shoe Dog: A Memoir by the Creator of Nike by Phil Knight. (Founders #186)

(35:00) I think one of the things that really separates us from the high primates is that we’re tool builders. I read a study that measured the efficiency of locomotion for various species on the planet. The condor used the least energy to move a kilometer. And, humans came in with a rather unimpressive showing, about a third of the way down the list. It was not too proud a showing for the crown of creation. So, that didn’t look so good. But, then somebody at Scientific American had the insight to test the efficiency of locomotion for a man on a bicycle. And, a man on a bicycle, a human on a bicycle, blew the condor away, completely off the top of the charts.

And that’s what a computer is to me. What a computer is to me is it’s the most remarkable tool that we’ve ever come up with, it’s the equivalent of a bicycle for our minds.

If you want me to speak at your company go here.

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

The Fish That Ate the Whale: The Life and Times of America's Banana King

The Presentation Secrets of Steve Jobs: How to Be Insanely Great in Front of Any Audience

The Invisible Billionaire: Daniel Ludwig

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Knowledge Project

The skills it takes to get rich are drastically different from the skills it takes to stay rich. Few understand this phenomenon more than Morgan Housel. He's identified unique lessons about wealth, happiness, and money by studying the world's richest families and learning what they did to build their wealth and just how quickly they squandered it all.
In this conversation, Shane and Housel discuss various aspects of risk-taking, wealth accumulation, and financial independence. Morgan explains the importance of understanding personal financial goals and the dangers of social comparison, lets everyone in on his personal financial “mistake” that instantly made him sleep better at night, and why the poorest people in the world disproportionately play the lottery—and why it makes sense that they do. They also touch on the influence of upbringing on financial behaviors, the difference between being rich and wealthy, and the critical role of compounding in financial success. Of course, we can’t have a writer as good as Morgan Housel on the podcast and not ask him about his process, so Housel concludes with insights into storytelling, his writing processes, and the importance of leading by example in teaching financial values to children.
Morgan Housel is a partner at Collaborative Fund. Previously, he was an analyst at The Motley Fool. He is a two-time winner of the Best in Business Award from the Society of American Business Editors and Writers and was selected by the Columbia Journalism Review for the Best Business Writing anthology. He's the author of two books: The Psychology of Money and Same as Ever.
Watch the episode on YouTube: ⁠https://www.youtube.com/c/theknowledgeproject/videos⁠

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(00:00) Intro

(04:46) Risk and income

(07:40) On luck and skill

(10:10) Buffett's secret strategy

(12:28) The one trait you need to build wealth

(16:20) Housel's capital allocation strategy

(16:48) Index funds, explained

(20:59) Expectations and moving goalposts

(22:17) Your house: asset or liability?

(27:39) Money lies we believe

(32:12) How to avoid status games

(35:04) Money rules from parents

(40:15) Rich vs. wealthy

(41:46) Housel's influential role models

(42:48) Why are rich people miserable?

(45:59) How success sows the seeds of average performance

(49:50) On risk

(50:59) Making money, spending money, saving money

(52:50) How the Vanderbilt's squandered their wealth

(1:04:11) How to manage your expectations

(01:06:26) How to talk to kids about money

(01:09:52) The biggest risk to capitalism

(01:13:56) The magic of compounding

(01:16:18) How Morgan reads

(01:22:42) How to tell the best story

(01:24:42) How Morgan writes

(01:35:42) Parting wisdom and thoughts on success

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What Bitcoin Did

Key Takeaways * Bitcoin is a technology for human empowerment; it enables better living through technology * You can have 100 opinions about everything that is wrong with the world, or you can focus on one thing and try to improve it; doing the latter may actually have an impact on upgrading the world * The solution to entrenched, systemic problems is the introduction of a new idea that goes viral * You change the world with elegant, diplomatic innovation, and not with hostile, full-frontal attacks * There is serious dysfunction all over the world: the answer is not to side with one party or politician against the other; the solution is to spread the Orange Wave * “Satoshi created a way. Satoshi gave it away. Satoshi went away.” – Michael Saylor * The more you know about economics and ethics, the more conservative and considerate you become about making changes to the protocol * You must consider the second-order effects and unintended consequences of implementing change * The focus should be on getting every powerful entity on earth to adopt bitcoin and converting potential enemies into friends * There is an explosion in global consensus that Bitcoin is an idea whose time has come * “Bitcoin is the most successful monetary protocol in the history of the world. It has gone from zero to $1.4 trillion in fifteen years. It looks like it’s on the path to go to $14 trillion, and I don’t know why it wouldn’t go to $140 trillion.” – Michael Saylor

Read the full notes @ podcastnotes.org

“I’m quite the optimist, I actually think that Bitcoin is going to succeed, it is succeeding, it’s succeeding as fast as it could reasonably succeed, and we ought to try to avoid the tendency to F with it.”
— Michael Saylor

Michael Saylor is the CEO of MicroStrategy. In this interview, we discuss ossification, user rights, sovereignty, funding Bitcoin development, the political war over digital asset regulation, and the sly roundabout revolution.

This episode’s sponsors:

IREN - Bitcoin Mining. Done Sustainably
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----- If you enjoy The What Bitcoin Did Podcast you can help support the show by doing the following: Become a Patronand get access to shows early or help contribute Make a tip: Bitcoin: 3FiC6w7eb3dkcaNHMAnj39ANTAkv8Ufi2S QR Codes: Bitcoin If you do send a tip then please email me so that I can say thank you Subscribe on iTunes | Spotify | Stitcher | SoundCloud | YouTube | Deezer| TuneIn | RSS FeedLeave a review on iTunesShare the show and episodes with your friends and family Subscribe to the newsletter on my websiteFollow me on Twitter Personal | Twitter Podcast | Instagram | Medium|YouTubeIf you are interested in sponsoring the show, you can read more about that here or please feel free to drop me an email to discuss options.

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How to Take Over the World

Key Takeaways * Check out Ben’s website

Read the full notes @ podcastnotes.org

George Washington is one of the most celebrated and beloved leaders of all time. What was it about Washington that made him such an effective leader? On this episode, we explore the making of George Washington: How he rose from relatively mundane origins to become the head of the American revolution.

Sponsors:
HensonShaving.com/takeover - Use code takeover for 100 free blades
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Sources:
Washington: A Life by Ron Chernow
George Washington: The Forge of Experience by James Thomas Flexner
On Seriousness

Writing, research, and production by Ben Wilson
Research assistance by Camille Doom
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Founders✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

What I learned from reading Driven From Within by Michael Jordan and Mark Vancil.

Relationships run the world: Build relationships at Founders events

Get access to the World’s Most Valuable Notebook for Founders

You can read, reread, and search all my notes and highlights from every book I've ever read for the podcast.

You can also ask SAGE any question and SAGE will read all my notes, highlights, and every transcript from every episode for you.

A few questions I've asked SAGE recently:

What are the most important leadership lessons from history's greatest entrepreneurs?

Can you give me a summary of Warren Buffett's best ideas? (Substitute any founder covered on the podcast and you'll get a comprehensive and easy to read summary of their ideas)

How did Edwin Land find new employees to hire? Any unusual sources to find talent?

What are some strategies that Cornelius Vanderbilt used against his competitors?

Get access to Founders Notes here.

Episode Outline:

Players who practice hard when no one is paying attention play well when everyone is watching.

It's hard, but it's fair. I live by those words.

To this day, I don't enjoy working. I enjoy playing, and figuring out how to connect playing with business. To me, that's my niche. People talk about my work ethic as a player, but they don't understand. What appeared to be hard work to others was simply playing for me.

You have to be uncompromised in your level of commitment to whatever you are doing, or it can disappear as fast as it appeared.

Look around, just about any person or entity achieving at a high level has the same focus. The morning after Tiger Woods rallied to beat Phil Mickelson at the Ford Championship in 2005, he was in the gym by 6:30 to work out. No lights. No cameras. No glitz or glamour. Uncompromised.

I knew going against the grain was just part of the process.

The mind will play tricks on you. The mind was telling you that you couldn't go any further. The mind was telling you how much it hurt. The mind was telling you these things to keep you from reaching your goal. But you have to see past that, turn it all off if you are going to get where you want to be.

I would wake up in the morning thinking: How am I going to attack today?

I’m not so dominant that I can’t listen to creative ideas coming from other people. Successful people listen. Those who don’t listen, don’t survive long.

In all honesty, I don't know what's ahead. If you ask me what I'm going to do in five years, I can't tell you. This moment? Now that's a different story. I know what I'm doing moment to moment, but I have no idea what's ahead. I'm so connected to this moment that I don't make assumptions about what might come next, because I don't want to lose touch with the present. Once you make assumptions about something that might happen, or might not happen, you start limiting the potential outcomes.

Get access to the World’s Most Valuable Notebook for Founders

You can read, reread, and search all my notes and highlights from every book I've ever read for the podcast.

You can also ask SAGE any question and SAGE will read all my notes, highlights, and every transcript from every episode for you.

A few questions I've asked SAGE recently:

What are the most important leadership lessons from history's greatest entrepreneurs?

Can you give me a summary of Warren Buffett's best ideas? (Substitute any founder covered on the podcast and you'll get a comprehensive and easy to read summary of their ideas)

How did Edwin Land find new employees to hire? Any unusual sources to find talent?

What are some strategies that Cornelius Vanderbilt used against his competitors?

Get access to Founders Notes here.

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

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Starting Greatness with Mike Maples

Key Takeaways * Be non-consensus, but right: Great startups identify something that is missing in the future that no one else realizes is missing * Figure out what you want that you can’t already get, then build it * It is important for the founders of a company to truly want the thing that they are creating * You must be willing to have thoughts and say things that cause investors to say, “that is the dumbest thing that I’ve ever heard” * You can succeed with a consensus idea if you are willing to relentlessly out-execute everyone else, but it is going to be much harder than succeeding with a non-consensus idea * Seek honest feedback from users and consumers instead of seeking validation from them * Have a broad hypothesis, but be open to the non-obvious thing when it presents itself or when you discover it * Winning is a mindset that pervades all else * Err on the side of over-persistence; people tend to give up before they really give something a shot

Read the full notes @ podcastnotes.org

Emmett Shear was a gamer long before he helped define one of the most important new media companies at the intersection of gaming, media, and the creator economy. What can we learn from his success as a founder? (hint: it has something to do with truly listening to users.) Check out the new Pattern Breakers Blog at patternbreakers.substack.comfor even more Pattern Breaking content from Mike. You can also pre-orderMike's new book Pattern Breakers wherever you buy books.

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James Altucher Show

Key Takeaways * Fears and risks are not reasons why we should not try to move forward and make positive use of new technologies * Educators must be explicit about why they are giving certain tasks, in addition to being more explicit about the types of tools that are acceptable and those that are not * AI will enable teachers to spend more time on the human connection part of their jobs * Few people retain most of what they are exposed to in school; in fact, 60-70% of kids who go to community college have to receive remediation, not even at a high school level, but at a 7th-grade level * Moving education to a competency-based system forces educators to get more clear about what they care about * There is a false tension between equity and competency; universities have artificially held capacity constant when it does not need to be * A question to consider: if you can solve a problem, can you use technology to help you scale any solutions that you have?

Read the full notes @ podcastnotes.org

A Note from James:

Oh my gosh, I've been wanting to have this guy on my podcast for literally ten years, ever since I started. I am so impressed with him, and he speaks about a subject near and dear to my heart. Salman Khan, Sal Khan, is the creator of Khan Academy, which was really the first big online academy. It focused on teaching math, coding, and other subjects, effectively reaching people who went through years of school without truly mastering these topics. Khan Academy has had a profound understanding of education and has become a huge phenomenon.

150 million students have used Khan Academy, with that number representing monthly users or registered accounts. Sal Khan recently authored a book on how AI will revolutionize education, titled "Brave New Words: How AI Will Revolutionize Education and Why That's a Good Thing." He discusses the use of AI in education for students, teachers, and employers, providing valuable insights into not only education but also AI and its impact on our lives. He addresses common fears about AI, its role in creativity, learning, and whether it will replace jobs or facilitate new employment opportunities.

I finally got the chance to interview Sal Khan about Khan Academy and AI. I learned so much, and I hope you will too.

Episode Description:

In this thought-provoking episode of The James Altucher Show, we embark on an exploratory journey into the future of education with none other than Salman Khan, the visionary founder of Khan Academy. As AI continues to seep into every facet of our lives, its potential to transform educational paradigms stands both as an opportunity and a profound challenge. Salman shares intriguing insights from his latest book, Brave New Words: How AI Will Revolutionize Education and Why That's a Good Thing, delving into AI's role not just as a disruptor, but as a potent catalyst for educational equity and innovation.

Salman's perspective is not just about theoretical possibilities; it's grounded in the tangible impact Khan Academy has had on democratizing education for millions globally. He recounts the Academy's genesis from humble beginnings — a series of YouTube tutorials for his cousin — to a global phenomenon. What stands out is his belief in AI's potential to further this mission, tailoring learning experiences to meet individual student's needs and inspiring both educators and learners to view AI as a partner, rather than a threat.

This episode is a beacon of optimism for educators, parents, and creatives alike, providing nuanced viewpoints on AI's implementation in classrooms, its potential to reshape content creation, and the critical role of humans in steering this technological revolution. Salman envisions a future where AI supports personalized learning journeys, making the exceptional accessible to many rather than a privileged few.

James engages Salman in discussions that span the philosophical to the practical, from concerns over AI-induced job displacement to the future of screenwriting in the age of algorithmic creativity. Yet, at its core, this dialogue returns always to the transformative potential of AI in enriching human understanding and connection — whether in interpreting Shakespeare or solving quadratic equations.

If you're looking for a blend of futurism with grounded optimism or curious about how technology could enhance human capabilities rather than replace them, this episode is an enlightening listen. As always, James brings his signature mix of curiosity and skepticism, pushing beyond surface-level concerns to uncover the deeper implications of our evolving relationship with AI. Listen in to reimagine what education could become in an AI-integrated world, and perhaps to catch a glimpse of how we might navigate these uncharted waters with wisdom and humanity at the helm.

Episode Summary:

00:00 Introduction to the Podcast and Sal Khan's Impact

03:00 Exploring Sal Khan's Personal Background

05:12 The Genesis of Khan Academy

08:26 Transitioning Khan Academy into a Nonprofit Giant

09:53 AI's Role in Revolutionizing Education

12:45 Addressing AI and Cheating in Education

16:03 The Future of Education and AI's Collaborative Potential

24:24 Reimagining the Role of Teachers in an AI-Enhanced World

29:43 Rethinking Education Systems for the Future

34:56 Personalized Learning and AI's Role

40:50 AI's Role in Education: Enhancing Teacher and Student Experiences

43:05 The Future of Education: Trends and AI Integration

44:37 Revolutionizing Assessments and Personalized Learning with AI

54:25 Addressing the Creative Industry's Concerns About AI

01:01:42 Parenting in the Age of AI: Opportunities and Challenges

01:15:34 The Future of Education Credentials and Access

01:20:26 Concluding Thoughts on AI's Impact on Education

Links and Resources:

"Brave New Words: How AI Will Revolutionize Education and Why That's a Good Thing" by Salman Khan and Other Creators - For more information on the book: https://www.amazon.com/Brave-New-Words-Revolutionize-Education/dp/1119824848
Khan Academy - A nonprofit educational organization offering free courses on a wide array of subjects: https://www.khanacademy.org
OpenAI and ChatGPT - Creators of the Generative Pre-trained Transformer AI models: https://openai.com
Tyler Perry - Filmmaker discussing the impact of AI on his industry decisions: https://tylerperry.com
Duke TIP (Talent Identification Program) - An example of advanced learning programs for youth: https://tip.duke.edu

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Skip the Line: The 10,000 Experiments Rule and Other Surprising Advice for Reaching Your Goals

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Jocko Podcast

Key Takeaways * You must account for your emotional state at the time in which you make a decision * Understand your instincts, and then lean in the other direction so that you are getting a more balanced approach * You fail when you receive valuable feedback, but choose to ignore it * Do not assume that your enemy thinks in a similar way that you do * Resist black-and-white thinking; you must learn to operate in the gray areas * Your team must know why they are being told to do something * Do not be extreme in your assessment * “Prioritize relationships. If you prioritize relationships, everything else is going to go better.” – Jocko Willink * Do not underestimate your opponent’s will and do not overestimate your own will * You must have full-and-frank discussions and listen to the other side * Keep an open mind and change the course when things are not working

Read the full notes @ podcastnotes.org

>Join Jocko Underground<

Exploring 11 lessons in the book, "In Retrospect", to live a better more informed life.

Support this podcast at — https://redcircle.com/jocko-podcast/exclusive-content

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Stuff You Should Know✓Claim

Key Takeaways * The Silurian Hypothesis is a thought experiment and scientific inquiry proposed by Adam Frank and Gavin Schmidt, exploring the possibility of advanced civilizations existing on Earth millions of years before humans * It does not claim that such civilizations existed but rather serves as a framework for considering how we might detect signs of ancient advanced societies * About one-tenth of 1% of all the species that have ever existed have had one of their individuals fossilized * In 88 million years, the Himalayan Mountains will be gone; it will just be a meadow where they once were * Future species will likely find evidence of our nuclear tests, which include compounds such as plutonium 244 and 129 * The earth’s surface erodes at 0.1 millimeters per year * Whether a civilization is long-lived or short-lived, the record it leaves will be a blimp on the geological record, in the grand scheme of time

Read the full notes @ podcastnotes.org

The idea that we aren’t the first advanced civilization to live on Earth sounds like a fringe theory, but it raises a good question: How can we be so sure that a civilization didn’t arise and die on Earth so long ago that any trace of it has been erased?

See omnystudio.com/listener for privacy information.

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Modern Wisdom

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Tim Ferriss is an entrepreneur, author, and podcaster.
Tim is one of the world’s leading thinkers and his podcast recently crossed 1 billion downloads. Today get to hear his biggest lessons from 2 decades of hacking life and self-improvement.
Expect to learn Tim’s ultimate hack for productivity, what his morning routine looks like, what Tim thought would make him happier when he was younger but didn't, how to deal with depression, which books Tim most often gifts, Tim's best 10 exercises for health & longevity, his thoughts on the current state of podcasting, how to avoid the perils of audience capture, how to cultivate self belief, secrets to becoming a high-performer and much more...
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

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Invest Like the Best

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

My guest today is Tim Ferriss. Tim is a writer, podcaster, and investor. He has written five best-selling books, has been an early-stage investor in Facebook, Uber, Shopify, & other household names, and is the host of one of the biggest podcasts in the world. He started The Tim Ferriss Show as an experiment in April 2014 and has deconstructed world-class performers ever since. Last year, his show crossed 1 billion downloads. Together, we deconstruct his podcast and approach to life. We talk about the art of interviewing, the business behind his podcast, and what motivates Tim to keep teaching through his writing and podcast. Please enjoy this great conversation with Tim Ferriss.

Check Out Invest America 2024
Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, the only investment research platform built for the investor. With traditional research vendors, the diligence process is slow, fragmented, and expensive. That leaves investors competing on how well they can aggregate data — not on their unique ability to analyze insights and make great investment decisions. Tegus offers an end-to-end platform with all the data you need to get up to speed on a company or market: up-to-the-minute financials, customizable models, management and culture checks, and, of course, our vast and growing library of expert call transcripts. Tegus is changing the world of expert research. Learn more and get your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:03:32) The Evolution of Podcasting with Tim Ferriss
(00:09:56) Crafting Meaningful Conversations
(00:13:26) What Makes Tim Feel The Most Alive
(00:24:06) Who Tim Considers To Be His Mentors
(00:29:06) The Ingredients Of A World Class Performance
(00:31:06) The Business Side of Podcasting
(00:43:15) Identifying Emerging Trends
(00:50:12) Lessons From Building a Small, Efficient Team
(00:52:32) The Power of Constraints in Personal and Professional Growth
(00:53:10) Innovating Against the Grain (Anti-Video Experiment)
(00:54:54) Navigating Fame, Money, and Power
(01:02:00) The Impact of Sharing Difficult Stories
(01:06:18) Meta-Learning: A Framework for Fast, Effective Learning
(01:12:32) Reflecting on a Decade of Podcasting & What’s In Store
(01:24:41) The Kindest Thing Anyone Has Ever Done For Tim

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Jocko Podcast

Key Takeaways * Curious about Andrew Huberman’s recipe for good sleep? Read more here

Read the full notes @ podcastnotes.org

>Join Jocko Underground<

Andrew Huberman, Ph.D., is a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. He has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning.

More at hubermanlab.com

Support this podcast at — https://redcircle.com/jocko-podcast/exclusive-content

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Rich Roll Podcast

Key Takeaways * Find your talent, not your passion: Being great at something that pays well will make you passionate about whatever that thing is * Fostering the American Middle Class is the country’s greatest innovation * You become a man when you add surplus value to society, i.e. when you produce more than you consume * People under the age of 40 used to control 19% of the GDP, in terms of their wealth; it has since been cut to 9% * “The most dangerous person in the world is a man who is broken and alone.” – Scott Galloway * America used to be about giving unremarkable kids remarkable opportunities; the country has since gone away from this * It is not obvious how to become economically secure without working hard * Billionaires will tell you to follow your passion, but they probably made their billions in iron ore and smelting * Near-peer adversaries will not choose to take on the U.S. kinetically; instead, they will likely use AI and other tools to attack America from within and exploit the ongoing loneliness epidemic * Young professionals should not fall victim to the “myth of balance”; it is very rare to achieve professional success while living a balanced life

Read the full notes @ podcastnotes.org

This week, I am joined by Scott Galloway, NYU professor, best-selling author, serial entrepreneur, and podcaster, to discuss the multifaceted challenges many young men face today. He underscores the lack of empathy and understanding many experience, attributing it to societal expectations and the impact of technology. Scott emphasizes the winner-take-most economy, which limits opportunities for many young men. Drawing from personal understanding, he stresses the importance of education, support, and the presence of positive male role models. The discussion encompasses economic challenges, the decline of mentorship programs, and the need for reform in higher education institutions. Addressing societal constructs of masculinity and the importance of vulnerability and integrity, Scott advocates embracing emotions and seeking help to navigate life’s hurdles. He stands apart as a model of healthy, grounded masculinity—one defined by humility, emotional intelligence, and a commitment to uplifting the collective rather than indulging narrow self-interest.

Enjoy!

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Invest Like the Best

Key Takeaways * The question to consider: Does AI help the strong get stronger, or does AI allow for new businesses to emerge and disrupt the incumbents? * The top five technology companies are spending 2x on capital expenditure than the top five energy companies * Companies should strive to increase the consumer’s willingness to pay * “Regulation is the friend of the incumbent.” – Bill Gurley * Venture capital is one of the few asset classes that has high persistence: the past winners tend to be future winners * Develop a framework that allows you to benefit from the group dynamics of pattern recognition, but that does not tie you to one specific type of pattern * Instead of nit-picking how an investment may fail, make the primary focus of the discussion: “How big could this be?” * Investors must capture the extreme events if they wish to outperform * The sharpest minds desire to know where they are wrong about something

Read the full notes @ podcastnotes.org

My guests today are Bill Gurley and Michael Mauboussin. Bill is a General Partner at Benchmark, and Michael is the Head of Consilient Research for Counterpoint Global. While they are longtime friends with one another, I’d never heard them appear somewhere together so it was a real treat to be able to do this with the two of them. They are two of the leading minds in their fields, and we combined their decades of expertise into one wide-ranging conversation. We discuss the different kinds of increasing returns to scale, the issue of regulatory capture, AI, and hardware. Please enjoy this great conversation with Bill Gurley and Michael Mauboussin.

Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, the only investment research platform built for the investor. With traditional research vendors, the diligence process is slow, fragmented, and expensive. That leaves investors competing on how well they can aggregate data — not on their unique ability to analyze insights and make great investment decisions. Tegus offers an end-to-end platform with all the data you need to get up to speed on a company or market: up-to-the-minute financials, customizable models, management and culture checks, and, of course, our vast and growing library of expert call transcripts. Tegus is changing the world of expert research. Learn more and get your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:03:38) Dissecting the Dynamics of AI, LLMs, and Market Disruption
(00:05:06) The World of AI Investments and Market Trends
(00:08:13) Integration of New Technologies in Business
(00:15:27) The Power of Increasing Returns and Strategic Investments
(00:22:26) Unpacking the Role of Intangibles in Scaling and Innovation
(00:28:54) Transformative Potential of Open Source and Idea Recombination
(00:34:42) The Complex Landscape of Regulation and Innovation
(00:43:17) Today’s Venture Capital Ecosystem
(00:47:08) Impact of Fewer IPOs and Private Market Dynamics
(00:50:38) Capital Allocation in Zero Interest Rate Environments
(00:54:44) The Evolution of Venture Capital and High-Stakes Investment Games
(00:57:21) Exploring New Frontiers: AI, Energy, and Physical World Innovations
(01:01:14) The Power of Learning by Doing
(01:17:49) Working with Genius
(01:26:47) The Value of Teaching, Writing, and Sharing Knowledge

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rational vc

Key Takeaways * People often underestimate the role of chance in their achievements * Mild success can be explainable by skill, but wild success is attributable to variance * In the long run, the “lucky” regress to the mean * Understand Power Laws when investing; the wins of a few investments make up for the losses on many investments, and then some * Survivorship Bias: the tendency to focus on successful individuals without considering those who failed due to random factors * The probability of the loss must be judged in connection with the magnitude of the outcome; it is not the likelihood of an event that matters, but the magnitude of the outcome in connection with the likelihood of the event that does * Maximizing the probability of winning does not maximize the expected value from the game * The confidence in which you make your decision is more important than the expected value that comes from that decision * A mistake is not something to be determined after the fact, but in the light of the information until that point

Read the full notes @ podcastnotes.org

Every podcast episode we explore a Lindy book, and find ideas you can use in business and life. Join 3,000+ curious minds and avid readers @ rationalvc.com to get free access to essays and exclusive content. For the video version of episode click here.

Timestamps:

(00:00) Intro / chit-chat
(20:11) Randomness & Luck
(24:46) Monte Carlo Simulation
(31:09) Ergodicity
(31:39) Hindsight Bias
(38:00) Survivorship Bias
(39:50) Asymmetric Bets / John & Nero
(49:53) Skewness & Asymmetry
(57:19) Pascal's Wager
(1:00:53) Induction & Chaos Theory
(1:03:22) Chapter 11
(1:08:45) System-1 vs System-2 Thinking
(1:10:03) Satisficing
(1:20:08) Normative vs Positive Thinking
(1:25:52) Signal vs Noise
(1:28:20) Heuristics
(1:33:45) Final Part of Book (Part 3's Importance)
(1:44:41) Favourite Quotes / Our Lives
(2:06:11) Final Thoughts

-

Our website (all essays and podcasts): rationalvc.com
Our investment fund: rational.fund
Cyrus' Twitter: x.com/CyrusYari
Iman's Twitter: x.com/iman_olya

-

Disclaimer: The materials provided are solely for informational or entertainment purposes and do not constitute investment or legal advice. All opinions expressed by hosts and guests are solely their own opinions and do not reflect the opinion of their employer(s).

#Lindy #knowledge #books

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Tetragrammaton with Rick Rubin✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Golden Harper is a lifelong runner and the founder of Altra Running Shoes. He ran his first marathon at age 10 (3:08:05) and holds the world’s best for a 12-year-old in the marathon at 2:45:34. After growing up working in his family’s running store, he studied Exercise Science (with a focus on running technique & running injuries) at Brigham Young University, where he was an All-American Cross-Country runner. His experience as a runner, combined with his education in proper running technique and biomechanics, led him to develop the world’s first foot-shaped, cushioned, zero-drop shoes.

Thank you to the sponsors that fuel our podcast and our team:

LMNT Electrolytes
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My First Million

Key Takeaways * You must have “one reason” to found a start-up; if you have five or six reasons to start it, then you have not yet found the single, very strong reason * Hire for raw IQ and hard work, then constantly iterate on solving the single problem at hand * Using your mind to its fullest capacity is the ultimate pleasure * The most successful people in the world are extremely focused and allow their focused efforts to compound over time * It is easy to identify conceptual gaps; developing the path toward closing that gap is the challenging part * You must figure out 1) what you are passionate about and 2) what you are good at * How you invest your time is more important than how you invest your capital, if wealth creation is your goal

Read the full notes @ podcastnotes.org

Episode 578: Shaan Puri ( https://twitter.com/ShaanVP ) sits down with Joe Lonsdale ( https://twitter.com/JTLonsdale ) to talk about how he leveraged one internship at PayPal into one billion dollar success after another.

Want to see Sam and Shaan’s smiling faces? Head to the MFM YouTube Channel and subscribe - http://tinyurl.com/5n7ftsy5
—
Show Notes:
(0:00) The One Reason strategy
(3:18) Learning Global Macro Finance from Peter Thiel
(5:35) Taking multi-million dollar bets at 4:30am
(8:43) Hire for raw IQ over expertise
(10:33) Nurturing employees into unicorn founders
(12:24) Solving hard problems with Addepar
(13:53) Always “Being on”
(15:32) How to spot opportunities for new businesses
(21:10) How Epirus landed a military defense contract
(27:09) Getting hits in hard domains
(28:24) Business Idea: AI-powered Estate Planning
(29:19) Business Idea: Business Process Outsourcing for local government
(30:58) Big swings vs. base hits
(31:49) Idea vs. execution
(32:38) Focus vs. diversity of thought/attention
(33:33) Insights from Elon’s inner circle
(35:36) Joe Lonsdale’s unfair advantages
(38:48) How to invest your time to make your first $1M
(40:40) Working on an A+ problem as an intern at PayPal
(43:15) Be within 2 standard deviations of top talent
(44:14) Early days at Palantir
(46:56) Building a top engineering culture
(48:31) Borrowing trust as 21-year old defense contractor
(52:22) Peter Thiel’s biggest contrarian bet

—
Links:
• Joe's Twitter - https://twitter.com/JTLonsdale
• Joe's blog - https://blog.joelonsdale.com/
• Addepar - https://addepar.com/
• Palantir - https://www.palantir.com/
• Epirus- https://www.epirusinc.com/
• OpenGov - https://opengov.com/
• Prologis - https://www.prologis.com/
• Lessons from Peter Thiel - https://joelonsdale.com/lessons-peter-thiel/

—
Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

—
Check Out Sam's Stuff:
• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth

My First Million is a HubSpot Original Podcast // Brought to you by The HubSpot Podcast Network // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.
—
Other episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

• #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Moonshots and Mindsets with Peter Diamandis✓Claim

Key Takeaways * Take a look at over 100 other Joe Rogan Notes!

Read the full notes @ podcastnotes.org

In this episode, recorded during the 2024 Abundance360 Summit, Ray, Geoffrey, and Peter debate whether AI will become sentient, what consciousness constitutes, and if AI should have rights.

01:12 | The Future of AI and Humanity

10:30 | The Ethics of Artificial Intelligence

25:00 |The Dangers and Possibilities of AI

Ray Kurzweil, an American inventor and futurist, is a pioneer in artificial intelligence. He has contributed significantly to OCR, text-to-speech, and speech recognition technologies. He is the author of numerous books on AI and the future of technology and has received the National Medal of Technology and Innovation, among other honors. At Google, Kurzweil focuses on machine learning and language processing, driving advancements in technology and human potential.

Geoffrey Hinton, often referred to as the "godfather of deep learning," is a British-Canadian cognitive psychologist and computer scientist recognized for his pioneering work in artificial neural networks. His research on neural networks, deep learning, and machine learning has significantly impacted the development of algorithms that can perform complex tasks such as image and speech recognition.

Read Ray’s latest book, The Singularity Is Nearer: When We Merge with AI

Follow Geoffrey on X: https://twitter.com/geoffreyhinton

Learn more about Abundance360: https://www.abundance360.com/summit
____________
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Modern Wisdom

Key Takeaways * Tips for improved cognition: Sleep, exercise, maintain good metabolic health & low risk of cardiovascular disease, give yourself blocks of time for focused work + Exercise for cognitive health: Train cardio in a ratio of 80:20, Zone 2:VO2 max * Warning: Doses of over the counter melatonin are supraphysiologic; reserve melatonin for jet lag but not as a daily sleep aid to avoid suppressing innate melatonin production * “If you have every single thing imaginable but you have no connection with other people, what do you have?” – Peter Attia * Poor emotional health is a threat to longevity + Your emotions matter but don’t just take them at face value; use them as cue to dive deeper below the surface and consider the origin + Considerations for emotional health: (1) Sense of purpose; (2) Satisfaction and joy; (3) achievement; (4) Quality of relationships; (5) Self-regulation; (6) Distress tolerance * The next time you are tempted to chastise yourself or use negative self-talk, try this instead: + Take out your phone and voice record a description of what you would say to a friend if they just committed the same act you were just about to punish in yourself + For example, instead of yelling at yourself for burning dinner, pull out your phone and record yourself talking to a friend who is upset they just burned dinner – you will find yourself much kinder to them than yourself + With practice, you will still remember the incident happened, but you will be able to move on easier without it ruining the day * TRT is safe in men who actually need it; the risk is in the supraphysiologic levels being administered to people who don’t need it and without proper guidance or supervision * Focus on healthspan and you’ll get the byproduct of improved lifespan * Stop giving into the noise! People spend way too much energy getting worked up about silly things instead of focusing on the big picture + The cereal is processed and made of junkier ingredients in the US than other places – but should you be eating the cereal in the first place?

Read the full notes @ podcastnotes.org

Dr Peter Attia is a physician, longevity expert, podcaster and an author.
There is essentially an unlimited amount of health advice available on the internet. Working out what is legit science and what is broscience is difficult, but thankfully decades of experience means Peter can help cut through the noise about what is actually most effective to improve your fitness and longevity.
Expect to learn why a simple hospital visit can cost $6000 in America, how to improve your cognition, the best supplements everyone should be taking, whether there is any safe dose of melatonin to take, why so many young men are now on TRT, how worried we should be about processed foods, suncream, alcohol and all of your other favourite vices, how we can better deal with mental decline as we age, how to improve your self-talk and much more...
Sponsors:
See discounts for all the products I use and recommend: https://chriswillx.com/deals
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Extra Stuff:
Get my free reading list of 100 books to read before you die: https://chriswillx.com/books
Try my productivity energy drink Neutonic: https://neutonic.com/modernwisdom
Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

Get In Touch:
Instagram: https://www.instagram.com/chriswillx
Twitter: https://www.twitter.com/chriswillx
YouTube: https://www.youtube.com/modernwisdompodcast
Email: https://chriswillx.com/contact
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Stuff You Should Know✓Claim

Key Takeaways * In the 1930s, the US Treasury took partial possession of Fort Knox so that it could store its gold there * Before Fort Knox, most of the United States’ gold was stored in New York City and Philadelphia, two cities that were close to the coast and potentially more vulnerable to an invasion from an adversary * Supposedly, there are 4600 metric tons of gold in the vault at Fort Knox; this equates to 2.5% of all the gold ever mined in human history * Some people believe that there is actually no gold in the vault * There have only been three official tours of Fort Knox since its founding * Fort Knox is hooked up to its own water and power supply; it can go “off-grid” * There is speculation that the field surrounding Fort Knox is a minefield

Read the full notes @ podcastnotes.org

When Fort Knox was built in the 1930s to house America’s gold supply, it was billed as an impenetrable, impregnable, don’t-even-think-of-trying vault. But as the world has moved further away from gold, the stockpile’s lost a bit of its luster. Learn all about it in this classic episode.

See omnystudio.com/listener for privacy information.

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Invest Like the Best

Key Takeaways * Success in business is all about culture, and bringing the very best people along with you as you embrace that culture * In negotiation, the other person should feel like they got more than what they thought they were going to get * The most important person in a company is the one who interacts with the customer * You want to work with people who have fight in them; work with people who can bounce back from defeat * Keep your word, work as hard as you can, and give it all you got

Read the full notes @ podcastnotes.org

My guest today is Ken Langone. Ken is a legendary American businessman best known for his co-founding of Home Depot. He is also a former director of the New York Stock Exchange and a passionate philanthropist. He shares with us a lifetime's worth of wisdom, building Home Depot into a powerhouse and prioritizing his employees above all else. He says he still “bleeds orange” to this day. You’ll hear as he recounts his business endeavors, his strict belief in keeping your word, and his true pride in his country, which he knows to be the land of opportunity. We discuss his work with Ross Perot, the idea of an upside-down hierarchy, and the power of loyalty. For anyone who may find it easier to follow along, we have a transcript of the episode on joincolossus.com. Please enjoy this conversation with Ken Langone.

Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, the go-to destination for bold investing. The investment research platform trusted by 95% of the top 20 global private equity firms just got even better. Building on their solid reputation for expert insights, Tegus has expanded to become the first true all-in-one research platform. The new Tegus makes diligence faster, easier, and more convenient than ever before. Your Tegus license gives you access to over 70,000 expert transcripts, more than 4,000 fully drivable financial models, and exclusive datasets like company management checks, industry KPIs, hard-to-find non-GAAP data, and more. Tegus is the fastest way to learn about a public or private company and the most cost-effective way to conduct investment research — now all under one roof. Learn more and get your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:004:00) The Unforgettable Pitch to Ross Perot
(00:08:37) Winning Over Perot with Honesty and Insight
(00:16:08) The Art of Negotiation and Trust
(00:19:31) Loyalty, Integrity, and the Power of Keeping Your Word
(00:23:51) Home Depot's Culture of Service and Empowerment
(00:29:16) Frank's Authentic Leadership and Its Impact
(00:31:00) Transforming NYU Medical Center
(00:33:45) Ken’s Investment Philosophy: Long Hold Only
(00:39:56) The Power of Resilience in Business
(00:45:37) The Kindest Thing Anyone Has Ever Done For Ken

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Stuff You Should Know✓Claim

Key Takeaways * Hormones do not act alone; they interact with many organs and neurotransmitters in the body * Testosterone & estrogen are more than just sex hormones – + Estrogen in females is important for bone growth, energy, muscle development, endurance, physical movement/urge to take action + Testosterone in males plays a role in mood, bone growth and development, muscle mass, and strength

Read the full notes @ podcastnotes.org

We think of estrogen and testosterone as the female and male sex hormones and they may seem kind of gross (is that just Josh?), but that simple understanding is way off. A magical biochemical dance between the two creates everything from bones to moods.

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Impact Theory with Tom Bilyeu

Key Takeaways * Curious about Andrew Huberman’s recipe for good sleep? Read more here

Read the full notes @ podcastnotes.org

Tom Bilyeu answers questions from the Impact Theory community and covers topics like the "Power of Myth" by Joseph Campbell, the evolution of mythology, and Millennials and the culture of the workplace.
[Original air date: January 28, 2017].

Tom Bilyeu is the co-founder of 2014 Inc. 500 company Quest Nutrition — a unicorn startup valued at over $1 billion — and the co-founder and host of Impact Theory. Impact Theory is a first-of-its-kind company designed to facilitate global change through the incubation of mission-based businesses and the cultivation of empowering content. Every piece of content Impact Theory creates is meant to underscore the company mission to free people from The Matrix and help them unlock their true potential. Impact Theory exists to inspire the next generation of game-changing companies and creators that will make a true and lasting impact on the world.

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Invest Like the Best

Key Takeaways * Dunbar’s number suggests that humans can maintain about 150 relationships at a given time * Humans have spent most of our lives in smaller, hunter-gatherer groups; existing together in large cities is a relatively new thing for the species * The best predictor of your mental and physical health – in addition to how long you are going to live into the future – is the number and quality of your closest relationships * There is a correlation between the number of friends people claim to have and the size of certain regions in their brains * “If you really want to live forever, just make sure you have five friends.” – Robin Dunbar * The emotional closeness of a relationship is highly correlated to the amount of time invested in it * Laughter, singing, and storytelling are how we foster emotional closeness with others without physical touch * Homophily is the tendency for people to seek out or be attracted to those who are similar to themselves; this is the driving force behind friendships * Face-to-face relationships are paramount: there is a significant difference between bonding with something in your head and with someone in the real world

Read the full notes @ podcastnotes.org

My guest today is Robin Dunbar. Robin is a biological anthropologist, evolutionary psychologist, and specialist in primate behavior. He is the man behind Dunbar’s number, a theory about the number of stable relationships we can maintain at once. Robin unravels the thread of research that led him to Dunbar’s number and describes how this plays into every single person’s layers of human connection. It was fascinating to hear how his findings on social circles have implications for optimally structuring businesses and organizations, as well as the idea of homophily, all of which Robin thoughtfully explains. It was a treat to get to explore these topics with Robin Dunbar himself so please enjoy this great conversation.

Listen to Founders Podcast
For the full show notes, transcript, and links to mentioned content, check out the episode page here.

This episode is brought to you by Tegus, the only investment research platform built for fundamental investors. Whether you’re trying to get up to speed on a new market or keep tabs on a portfolio company, Tegus is the end-to-end investment research platform you need. With Tegus, you can quickly understand a company's business model, drivers, benchmarks, and management quality. To monitor an entire market, download our pre-built financial models — or update your own with the latest data using Tegus’ new Excel Add-In. Tegus gives you all of this and more, all bundled into a single software license. Find out why 95% of the top 20 global private equity firms are Tegus customers. Learn more and get your free trial at tegus.com/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.
Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @patrick_oshag | @JoinColossus
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).
Show Notes:
(00:00:00) Welcome to Invest Like the Best
(00:04:39) The Journey to Discovering Dunbar's Number
(00:07:28) Exploring the Layers of Human Connection
(00:12:27) The Significance of the 1.5 Layer in Social Circles
(00:16:55) Surprising Insights from Social Network Studies
(00:20:40) Applying Dunbar's Number to Organizational Structures
(00:27:51) The Science of Social Bonding in Primates and Humans
(00:33:23) Unlocking the Endorphin System Without Physical Touch
(00:34:10) The Power of Laughter, Singing, and Storytelling in Group Bonding
(00:36:00) The Limitations of Digital Interactions for Building Relationships
(00:39:51) Reviving Social Clubs and Activities for Workplace Bonding
(00:44:40) The Importance of Homophily in Friendships and Social Networks
(00:50:40) Challenges and Solutions for Overcoming Loneliness and Building Trust
(00:53:45) The Impact of Technology, Religion, and Mental Health on Social Connections
(00:61:47) Reflecting on Time as a Fundamental Aspect of Social Dynamics

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Modern Wisdom

Key Takeaways * The key question to consider about work and productivity: “How do we produce stuff, and be proud and ambitious about what we are doing, but also not burn out?” * Pseudo-productivity places too great an emphasis on looking busy but not creating anything of value; it is busyness for the sake of busyness because measuring productivity any other way in the knowledge work sector is too difficult * Do not shatter your day into fragments so small that you get nothing meaningful done * History’s greatest knowledge workers worked very slowly * Doing fewer things at once will enable you to accomplish more things * Your results are determined by intensity in the short term and consistency in the long term * Never give a yes or a no in the room; not saying yes or no in the room creates psychological distance from the decision * “Busyness” is attractive to people because it is a goal that they can succeed at; if a person wants to be busy, they will be busy * Signal to others that you are very careful about your time * “People who obsess over quality grow antibodies to busyness.” – Cal Newport

Read the full notes @ podcastnotes.org

Cal Newport is a computer science professor at Georgetown University, a productivity expert and an author.
If you’ve ever felt that you’re not as productive as you could be, you’re not alone. But what if the goal isn't to be more productive, but to let go of the goals that aren't serving you? What if the power of saying no to more things is the most important skill you can develop?
Expect to learn what our current problem with being productive is, why pseudo-productivity is a catastrophe, the advantages to what Cal calls Slow Productivity, how to better organise your communication, the best strategies for implementing a productivity schedule, how to stop saying yes all the time and much more...
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Episodes You Might Enjoy:

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

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Stuff You Should Know✓Claim

Key Takeaways * Check out these Podcast Notes on Stuff You Should Know About Manhunts

Read the full notes @ podcastnotes.org

For a learning disability that everyone seems to know about, dyslexia is maybe the most commonly misunderstood and controversial cognitive difficulty there is. Some people think it’s a gift, some people think it doesn’t even exist. Learn more in this classic episode.

See omnystudio.com/listener for privacy information.

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Stuff You Should Know✓Claim

Key Takeaways * The Love Canal neighborhood in Niagara Falls, New York was the site of the worst environmental disaster involving chemical waste in U.S. history * The site was eventually filled in, and years later after selling the land to the City of Niagara for $1, housing developments and a school were built on top of it * In just a few years after people started living in the area, some people began developing horrible physical defects, and the rate of birth defects skyrocketed * Many residents who moved into the area had no idea that toxic waste was stored below them * In 1976, the Niagara Gazette published the first article that explained the origins of the Love Canal neighborhood, explaining the history of the Hooker Company and the toxic waste that was buried beneath the soil * It took several years for the issue to be acknowledged; several city-sponsored investigations took place, but the results were not shared with the local populous * Grassroot initiatives, led by Lois Gibbs, eventually brought national media attention to the crisis; her efforts led to $50+ million in federal and state funding to mitigate the effects of the disaster * A state of emergency was declared, the town was eventually shut down and flattened, and all but two families left Love Canal * People have since moved back into the area, which is now known as Black Creek; today, some of the people living in the town remain unaware of the history of Love Canal

Read the full notes @ podcastnotes.org

A man with an unfulfilled vision left a huge gash in the ground near Niagara Falls. Then a chemical company came along and filled it with toxic waste. Then people came along and built homes and an elementary school on top of it. Then things went badly.

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The Weirdest Thing I Learned This Week

Key Takeaways * A common interpretation across civilizations is that solar eclipses happen when the people on earth have done something bad * Another popular interpretation of solar eclipses is that when humans were fighting too much on Earth, the sun and the moon would begin to fight in the sky * In ancient civilizations, evidence of human sacrifices is common in places where eclipses occurred * Today is the most cosmically perfect time in the history of the universe; the fact that we can see eclipses at all is a complete coincidence * In 620 million years, the moon will be far away enough from Earth that we will no longer have total eclipses, only partial eclipses * No other rocky planet in the solar system has a moon large enough to cause a total eclipse * After the April 8th, 2024 solar eclipse, the next viewable solar eclipse in the United States won’t be until 2040

Read the full notes @ podcastnotes.org

Scientific American's Lee Billings and Clara Moskowitz join Rachel this week to talk all things eclipse.
The Weirdest Thing I Learned This Week is a podcast by Popular Science. Share your weirdest facts and stories with us in our Facebook group or tweet at us!
Click here to learn more about all of our stories!
Links to Rachel's TikTok, Newsletter, Merch Store and More: https://linktr.ee/RachelFeltman
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Ben Greenfield Fitness

Key Takeaways * The future is now with stem cell treatments for longevity – stem cell treatments can be targeted, dosed, and have predictable outcomes like pharmaceuticals + In early trials, stem cells transplanted into the brain created new dopamine neurons and put Parkinson’s disease into remission * To tackle longevity, we need to go back to first-order principles of wellness: muscle, inflammation, oxidative stress * Tip: have an accountability system, whether it’s a health coach or buddy who will hold you to it * Medicine 4.0 is on the horizon, allowing people greater access to gene therapy treatments to help people increase their healthspan + Look out for klotho, NK cell treatments, placental implants, and Vagus nerve blocks to become common practice

Read the full notes @ podcastnotes.org

Are you tired of feeling the effects of aging, like sluggish muscles, persistent inflammation, and a general slowdown? Imagine receiving a treatment that not only decelerates these processes but also enhances muscle growth and restores your energy at the cellular level.

In this episode, Dr. Adeel Khan, a repeat guest, unveils the revolutionary treatments offered at his clinic, Eterna Health, such as follistatin gene therapy and Klotho injections. These cutting-edge treatments combat the aging process, helping you feel youthful and vibrant — stay tuned to hear about my personal experience during my visit to his Cabo location.

As the CEO and founder of Eterna Health, a revolutionary concept in specialized healthcare, Dr. Khan's allure extends beyond borders. Patients from across the globe seek out his unwavering dedication to understanding cellular physiology and the art of cellular repair, leading to collaborations with scientists in Canada, the USA, Mexico, Dubai, Italy, and Japan.

Dr. Khan’s grand vision reaches beyond personal success. His ultimate aspiration is to democratize regenerative medicine, making it affordable and accessible to people from all walks of life.

Join Dr. Khan and me as we explore the benefits of cutting-edge treatments for slowing down the aging process, enhancing muscle growth, improving overall health, and innovative approaches to regenerative medicine, shedding light on the future of anti-aging therapies.

Oh, and if you didn't catch our first interview together, I highly recommend checking that out here: “The Difference Between Getting Stem Cells Internationally Vs. The USA, Peptides, Testosterone & Hormones, Tissue Engineering, DNA Editing, Truths & Myths Of Regenerative Medicine & More.”

For the full show notes, visit: https://bengreenfieldlife.com/eternapodcast

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Jigsaw Health: Visit JigsawAC.com and use “Greenfield10” to get 10% off on your order.

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Limitless Life Nootropics: Visit limitlesslifenootropics.com/bengpeptides and use code BEN for an exclusive discount.

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Business Breakdowns✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

This is Zack Fuss. Today we are breaking down the Mitsubishi Corporation. In Japan, the business model of a trading company is prominent. The big five trading companies caught the attention of global investors in 2020, when Berkshire Hathaway disclosed a major stake in all of them: Mitsubishi, Mitsui, Itochu, Marubeni, and Sumitomo. Today's Berkshire stake is nearly 10%.
I'm joined by Krishna Mohanraj, a Portfolio Manager at Diamond Hill Capital Management. In this episode, we discuss how the rich history of trading houses is steeped in Japanese culture and how each differs from one another. Krishna helps unravel the evolution of stakeholder priorities and how capital allocation policies have changed in the Japanese capital markets. Please enjoy this Breakdown of Mitsubishi Corporation.

Interested in hiring from the Colossus Community? Click here.

For the full show notes, transcript, and links to the best content to learn more, check out the episode page here.

This episode is brought to you by Tegus, the only investment research platform built for the investor. With traditional research vendors, the diligence process is slow, fragmented, and expensive. That leaves investors competing on how well they can aggregate data — not on their unique ability to analyze insights and make great investment decisions. Tegus offers an end-to-end platform with all the data you need to get up to speed on a company or market: up-to-the-minute financials, customizable models, management and culture checks, and, of course, our vast and growing library of expert call transcripts. Tegus is changing the world of expert research. Learn more and get your free trial at tegus.com/patrick.

Business Breakdowns is a property of Colossus, LLC. For more episodes of Business Breakdowns, visit joincolossus.com/episodes.
Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.
Follow us on Twitter: @JoinColossus | @patrick_oshag | @zbfuss | @ReustleMatt | @domcooke
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).

Show Notes
(00:00:00) Welcome to Business Breakdowns
(00:03:12) First Question - Understanding Mitsubishi's Global Impact and Business Model
(00:07:12) The Evolution of Mitsubishi and Japanese Trading Houses
(00:12:12) Mitsubishi's Investment Case and Market Position
(00:15:02) Comparing Mitsubishi with Other Japanese Trading Houses
(00:18:22) The Secret to Mitsubishi's Success and Global Network
(00:21:16) The Relevance of Berkshire’s Investment in the Japanese Trading Houses
(00:26:45) A Cultural Shift in the Orientation of Japanese Businesses Towards Their Shareholders
(00:28:35) Valuing Mitsubishi
(00:31:05) Reinvesting in The Business And Reallocating Capital
(00:33:02) Mitsubishi’s Unique Management Dynamic
(00:38:54) Advantages of the Mitsubishi Group
(00:42:44) Lessons Learned from Mitsubishi
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Moonshots and Mindsets with Peter Diamandis✓Claim

Key Takeaways * Get Peter’s new Longevity Practices book for free

Read the full notes @ podcastnotes.org

In this episode, recorded during the 2024 Abundance360 Summit, Peter and Elon discuss super-intelligence, the future of AI, Neuralink, and more.

01:01 | The Power and Perils of Superintelligence

16:58 | Neuralink: Merging Humans with Technology

24:31 | A Step Closer to Multiplanetary Life

Elon Musk is a businessman, founder, investor, and CEO. He co-founded PayPal, Neuralink and OpenAI; founded SpaceX, and is the CEO of Tesla and the Chairman of X.

Learn more about Abundance360: https://www.abundance360.com/summit
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Tetragrammaton with Rick Rubin✓Claim

Key Takeaways * Your eye is like a clock, telling the time through light exposure; the light that comes into our eyes is seen by a lot of the processes going on inside our body * The defect is not solely in your genes, it’s in your environment * The organization of the melanin inside your body contributes to chronic disease * Be an observer of nature – never stop asking questions * Think in a decentralized fashion, not a reductionist * Melanin allows us to keep proper time so that the motor function happens and is coordinated at the right time – light exposure can set the stage for disease if you’re not getting enough * Pay attention to the light and the dark – exposure to both matters for your health * “When you change your environment, you can change your thoughts.” – Dr. Jack Kruse * We ignore our body’s needs for our wants; it’s our duty to understand our body – this will improve our health * Anything you can do to get more sunlight, and more hours of the day is beneficial for our health + Tip: eat food within your circadian cycle; eat local produce that makes sense for your region

Read the full notes @ podcastnotes.org

Dr. Jack Kruse is a neurosurgeon who had an awakening in 2007 after suffering a torn meniscus. This led to his study of physics, light, magnetism, and electricity. He ultimately concluded that modern medicine lacked a deep understanding of how humans function in relation to the natural world. Kruse lost 150 lbs. using his newly acquired understanding. He is CEO of Kruse Longevity Center, a health and wellness company dedicated to helping patients avoid the healthcare burdens typically encountered with age.

Bill Gifford is coauthor, with Peter Attia, of Outlive, a current New York Times bestseller. He is a veteran journalist and editor who has written extensively on science, sports, and fitness for Wired, Businessweek, Men's Health, Men's Journal, Slate, and The New Republic. He is also the author of books like Ledyard: In Search of the First American Explorer and Spring Chicken: Stay Young Forever (or Die Trying).

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Founders✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

What I learned from reading The Lessons of History by Will and Ariel Durant.

Get access to the World’s Most Valuable Notebook for Founders at Founders Notes

Follow Founders Podcast on YouTube

(1:00) This is a 100 page biography of the human species

(1:00) The Story of Civilization by Will and Ariel Durant (Full Set)

(2:30) Generations of men establish a growing mastery over the earth, but they are destined to become fossils in its soil.

(4:00) Ruthlessly prioritize how you spend your time.

(4:00) The influence of geographic factors diminishes as technology grows.

(4:30) ALL OF THE NAPOLEON EPISODES:

Napoleon: A Concise Biography by David Bell. (Founders #294)

The Mind of Napoleon: A Selection of His Written and Spoken Wordsedited by J. Christopher Herold. (Founders #302)

Napoleon and Modern War by Napoleon and Col. Lanza. (Founders #337)

(8:00) Our job is to make our companies and ourselves better equipped to meet the test of survival.

(11:30) Economic development specializes functions, differentiates abilities, and makes men unequally valuable to their group.

(12:30) The Almanack of Naval Ravikant: A Guide to Wealth and Happiness by Naval Ravikant and Eric Jorgenson. (Founders #191)

(14:30) In the end, superior ability has its way.

(16:30) Nothing is clearer in history than the adoption by successful rebels of the methods they were accustomed to condemn in the forces they deposed.

(19:00) The imitative majority follows the innovating minority and this follows the originative individual, in adapting new responses to the demands of environment or survival.

(20:00) If you can identify an enduring human need you can build a business around that.

(21:00) In every age men have been dishonest and governments have been corrupt.

(25:00) Survival at all costs: Nature and history do not agree with our conceptions of good and bad; they define good as that which survives, and bad as that which goes under.

(25:00) Victory in our industry is spelled survival. — Steve Jobs

(25:00) All that matters is to survive. The rest is just words. — Charles de Gaulle by Julian Jackson. (Founders #224)

(26:00) By being so cautious in respect to leverage and having loads of liquidity, we will be equipped both financially and emotionally to play offense while others scramble for survival. — The Essays of Warren Buffett by Warren Buffett and Lawrence Cunningham (Founders #227)

(27:00) History reports that the men who can manage men manage the men who can manage only things, and the men who can manage money manage all.

(31:00) The Iron Law of Oligarchy

(32:00) Every advance in the complexity of the economy puts an added premium upon superior ability.

(33:00) The General and the Genius: Groves and Oppenheimer—The Unlikely Partnership that Built the Atom Bomb by James Kunetka. (Founders #215)

(34:00) Freedom's Forge: How American Business Produced Victory in World War II by Arthur Herman

(37:00) All technological advances will have to be written off as merely new means of achieving old ends

Get access to the World’s Most Valuable Notebook for Founders at Founders Notes

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

Mind of Napoleon: A Selection of His Written and Spoken Words

Freedom's Forge: How American Business Produced Victory in World War II

The General and the Genius: Groves and Oppenheimer - The Unlikely Partnership that Built the Atom Bomb

The Story of Civilization [Volumes 1 to 11] (Hardcover Set 1963-1975)

The Almanack of Naval Ravikant: A Guide to Wealth and Happiness

The Essays of Warren Buffett: Lessons for Corporate America, Fifth Edition

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Found My Fitness - Rhonda Patrick

Key Takeaways * Magnesium is an essential mineral required for more than 300 metabolic reactions in the body but almost half the U.S. does not have sufficient levels (partly because of poor diet) * One theory of aging: when we have suboptimal dietary intake, our body sacrifices the long term for the short term, producing insidious damage overtime that accelerates aging * Stress will lower magnesium levels, even for days after stress passes * Flaws of supplement and nutritional study design: randomized controlled trials are the gold standard for pharmaceutical interventions, but, nutritional studies need to consider individual nutrition and improve study design at the outset with consideration for baseline levels of participants if we want real answers + Most studies are also observational so you can’t infer causality + Micronutrients also often work in conjunction with one another – for example, magnesium is necessary for the conversion of vitamin D into its most stable form * Most of the positive benefits of magnesium come from studies on dietary magnesium not supplementation + Confounding: magnesium is found in leafy greens, legumes, nuts, fish – and healthier foods; it may not be solely the magnesium that’s improving health

Read the full notes @ podcastnotes.org

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In this solo episode, I'm taking an in-depth look at magnesium – a critical yet frequently underestimated mineral in our health. Magnesium stands tall among vital nutrients for its significant role in multiple aspects of human physiology. During this podcast, we'll delve into the widespread negative health effects caused by a lack of magnesium and discuss why increasing your magnesium intake might be key to achieving optimal health.

In this episode, I discuss:

(00:04:27) Why the effects of magnesium are far-reaching
(00:06:47) Why athletes need at least 10-20% more magnesium than the RDA
(00:10:54) Why magnesium deficiency & insufficiency are common
(00:12:19) How to determine if you're getting enough magnesium
(00:12:23) The problem with magnesium blood tests
(00:15:14) Magnesium supplements
(00:18:17) Is magnesium threonate better at crossing the blood-brain barrier?
(00:25:08) Why magnesium threonate shouldn't count toward your RDA goal
(00:17:50) The effectiveness of epsom salt baths (see also 01:12:41)
(00:26:04) What magnesium supplement do I take?
(00:26:31) The effect of stress on magnesium balance
(00:30:15) Why the energy demands of workouts affect magnesium balance
(00:32:56) Does magnesium supplementation improve sleep?
(00:34:04) Why trials in the field of nutrition are often misleading
(00:37:26) Does higher magnesium intake improve cognition?
(00:39:07) Does magnesium have a role in preventing Alzheimer's disease?
(00:42:09) The effect of creatine on the brain (and its relationship to magnesium)
(00:42:42) Why magnesium may prevent excitotoxicity in the brain
(00:43:32) Magnesium's potential for managing migraines
(00:46:41) The role of magnesium in aging
(00:47:39) Why magnesium deficiency impairs DNA repair
(00:49:13) Magnesium's role in cancer prevention
(00:51:14) Why magnesium is intertwined in genomic stability
(00:54:04) Why we shouldn't disregard observational data in nutrition
(00:54:52) How magnesium intake affects mortality risk and cancer
(00:57:49) Magnesium in osteoporosis prevention
(00:59:21) Why magnesium intake in early life affects bone accretion
(01:01:06) The effect of magnesium on vitamin D metabolism
(01:06:36) Does magnesium treat high blood pressure?
(01:10:12) Does magnesium help manage muscle cramps?
(01:12:41) Is transdermal absorption of magnesium effective?

Watch this episode on YouTube

Show notes are available by clicking here

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My First Million

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Episode 562: Shaan Puri (https://twitter.com/ShaanVP) and Sam Parr (https://twitter.com/theSamParr) get into the economics of personality tests–including the most famous one which is used by 89% of Fortune 100 companies.
Want to talk to Shaan? Text “hi” to 650-334-0790
Want to see Sam and Shaan’s smiling faces? Head to the MFM YouTube Channel and subscribe - http://tinyurl.com/5n7ftsy5

—
Show Notes:
(0:00) Intro
(1:00) Data mining the basketball court
(7:00) Origin of Myers-Briggs Test
(14:30) Formula for Grit
(16:00) Sam takes the Grit Scale Test
(23:00) Cognition Labs, a math nerd's wet dream
(34:00) Be willing to walk backwards
(39:50) Speedrunning: 3 Founders Who Repeated the Playbook
(42:00) Don't explore, exploit
(49:00) $600M protein bar in 4 years

—
Links:
• Grit - https://angeladuckworth.com/grit-book/
• Gallup - https://www.gallup.com/
• Lunchclub - https://lunchclub.com
• Cognition - https://www.cognition-labs.com/
• Gold-Medalist Coders article - https://tinyurl.com/tc65a2vc
• David Protein - http://davidprotein.com/

—
Check Out Sam's Stuff:
• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth

—
Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.
—
Other episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

• #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Impact Theory with Tom Bilyeu

Key Takeaways * Inflation is a hidden tax on the people; instead of the government openly taking your money with direct taxation, it creates new money out of thin air which robs people of their purchasing power * Governments debase their currency because they know there is no other way to pay their existing debts * In the United States, houses used to cost about 3x the median income; now they cost about 10x the median income * “If it doesn’t have intrinsic value, then it’s not going to be money.” – Peter Schiff * “This is the best macro opportunity of all time.” – Raoul Pal on bitcoin * People wrongly assume that the dollars we print will always have value, regardless of how many dollars are printed * Central banks are paying the debts by printing money; this is pure monetary debasement * Papering over the debts with more printed money does not solve the fundamental problem * Politicians do not do what is best for the country; they do what is best for their careers, which is often at odds with what is best for the country * “They are going to keep on printing until the dollar collapses.” – Peter Schiff * The free market tries to lower prices by increasing productivity while the government tries to raise prices by creating inflation * Using inflation to melt away existing debts is not the “right” choice, but it is the expedient choice – and likely the option that politicians will choose * We will deal with the consequences of currency debasement once the can cannot be kicked any further down the road

Read the full notes @ podcastnotes.org

Welcome back to part 2 of this power-packed debate with Peter Schiff and Raoul Pal!
The discussion continues as we dive deeper into:

The growing national debt and potential hyperinflation
Historical patterns of financial repression
Blockchain technology and digital asset utilization
The future of Social Security

You won’t want to miss out on the final part of this hot debate between Raoul Pal and Peter Schiff.
And if you're loving the Impact Theory Podcast, please take a moment to leave us a review or rate the show. Your feedback is incredibly valuable!

Follow Raoul Pal:
Website: https://www.realvision.com/
Twitter: https://twitter.com/RaoulGMI
LinkedIn: https://www.linkedin.com/in/raoul-pal-real-vision/
YouTube: https://www.youtube.com/@RealVisionFinance/featured

Follow Peter Schiff:
Website: https://schiffradio.com/
X: https://twitter.com/PeterSchiff
YouTube: https://www.youtube.com/@peterschiff/featured

Follow Me, Tom Bilyeu:
Website: https://impacttheoryuniversity.com/
X: https://twitter.com/TomBilyeu
Instagram: https://www.instagram.com/tombilyeu/

If you want to dive deeper into my content, search through every episode, find specific topics I've covered, and ask me questions. Go to my Dexa page: https://dexa.ai/tombilyeu

Themes: Mindset, Finance, World Affairs, Health & Productivity, Future & Tech, Simulation Theory & Physics, Dating & Relationships

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Founders✓Claim

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

What I learned from rereading Tycoon's War: How Cornelius Vanderbilt Invaded a Country to Overthrow America's Most Famous Military Adventurer by Stephen Dando-Collins.

Get access to the World’s Most Valuable Notebook for Founders at Founders Notes

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(0:01) Vanderbilt was only interested in two things: making money and winning

(3:00) Cornelius Vanderbilt, the descendant of poor Dutch immigrants, would die in 1877 possessing more money than was held by the United States treasury.
(3:00) The First Tycoon: The Epic Life of Cornelius Vanderbilt by T.J. Stiles

(5:00) The NEW Poor Charlie's Almanack: The Wit and Wisdom of Charlie Munger. (Founders #329)

(6:00) “If I had learned education. I would not have had time to learn anything else.”

(7:00) Vanderbilt wrote nothing down, keeping every detail of his business dealings in his head, and at any given time he knew his income and expenditures down to the last cent.

(10:00) From Founders Notes. I asked the chat feature:

Tell me about Cornelius Vanderbilt. How did he make his money?

One trait it identified in Vanderbilt was this:

Vanderbilt's approach to business was often marked by a sly concealment of his intentions, keeping information close while simultaneously gathering intelligence on competitors. This strategic obfuscation allowed him to make moves that others often couldn't predict or comprehend until it was too late

(This feature will be available to Founders Notes subscribers very soon!)

(15:00) The Invisible Billionaire: Daniel Ludwig by Jerry Shields (Founders #292)

(24:00) The Founders: The Story of PayPal and the Entrepreneurs Who Shaped Silicon Valley by Jimmy Soni. (Founders #233)

(26:00) Gentlemen, you have undertaken to cheat me. I won’t sue you, for the law is too slow. I’ll ruin you. Yours truly, Cornelius Vanderbilt.

(37:00) He's turning everyone against Walker by appealing to their interests. He’s not saying do this for me to get my ships back. He appeals to their interests and aligns their interests with his own.

(40:00) Vanderbilt had more money than all the Central American governments combined.

(41:00) As far as my nature is concerned, I do not meet competition, I destroy competitors.

— The 38 Letters from J.D. Rockefeller to His Son by John D. Rockefeller. (Founders #324)

(41:00) Vanderbilt said why don’t you pay me to not compete with you?

Get access to the World’s Most Valuable Notebook for Founders at Founders Notes

“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

The First Tycoon: The Epic Life of Cornelius Vanderbilt

Tycoon's War: How Cornelius Vanderbilt Invaded a Country to Overthrow America's Most Famous Military Adventurer

The Founders: The Story of Paypal and the Entrepreneurs Who Shaped Silicon Valley

The 38 Letters from J.D. Rockefeller to his son: Perspectives, Ideology, and Wisdom (English Version) Paperback 2nd Edition

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Deep Questions with Cal Newport✓Claim

One of the most common strategies for achieving a powerful ideal lifestyle vision is to leverage entrepreneurial activities to find a stable source of income that allows autonomy and flexibility. To help understand how to succeed in such ventures, Cal interviews the entrepreneur and author Noah Kagan about his new book, "The Million Dollar Weekend." Recording on the road as part of his book tour for "Slow Productivity," Cal also shares some lessons about what he's been observing.

Below are the questions covered in today's episode (with their timestamps). Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo

Video from today’s episode: youtube.com/calnewportmedia

INTERVIEW: Marketing guru Noah Kagan [11:06]

Links:
Use this link to preorder a signed copy of “Slow Productivity”:
peoplesbooktakoma.com/preorder-slow-productivity/
FREE download excerpt and 2 Bonuses for “Slow Productivity”:
calnewport.com/slow

Thanks to our Sponsors:

This show is brought to you by BetterHelp. Give online therapy a try at
betterhelp.com/deepquestions
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Thanks to Jesse Miller for production, Jay Kerstens for the intro music, Kieron Rees for slow productivity music, and Mark Miles for mastering.

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My First Million

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Episode 559: Sam Parr (https://twitter.com/theSamParr) talks to Ramit Sethi ( https://twitter.com/ramit ) about why buying a house makes zero financial sense.
Want to see Sam and Shaan’s smiling faces? Head to the MFM YouTube Channel and subscribe - http://tinyurl.com/5n7ftsy5
—
Show Notes:
(0:00) Intro
(3:30) Set your rich life intention
(7:30) Don't confuse luck with skill
(8:00) Sam's journey from owner to renter
(11:30) Do the math: Real cost of ownership
(15:30) Buy for desire
(17:30) Pay in cash for large purchases
(19:00) The 10 year rule
(24:30) Ramit's list of must-haves
(29:00) Sam's dream house
(32:00) Sam's war on stuff
(39:00) When to overspend
(44:00) Millionaires who rent

—
Links:
• Ramit on Twitter - https://twitter.com/ramit
• Ramit on YouTube - https://tinyurl.com/m2s8cuyp
• I Will Teach You To Be Rich - https://www.iwillteachyoutoberich.com/

—
Check Out Shaan's Stuff:
Need to hire? You should use the same service Shaan uses to hire developers, designers, & Virtual Assistants → it’s called Shepherd (tell ‘em Shaan sent you): https://bit.ly/SupportShepherd

—
Check Out Sam's Stuff:
• Hampton - https://www.joinhampton.com/
• Ideation Bootcamp - https://www.ideationbootcamp.co/
• Copy That - https://copythat.com
• Hampton Wealth Survey - https://joinhampton.com/wealth

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.
—
Other episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

• #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Infinite Loops

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Devon Eriksen always wanted to be a writer. As a child, he was persuaded to abandon his aspirations in favor of a career in software engineering. Two decades later, he retired to finally fulfil his ambition to write imaginative hard-science fiction in the vein of authors like Asimov, Heinlein and Niven. He self-published his first novel, Theft of Fire, last year to an excellent reception.

Devon joins the show to discuss why his book incorporates alien technology, the role of patronage in the digital era, his unusual approach to obtaining feedback, and MUCH more!

Important Links:

Theft of Fire; by Devon Eriksen
Devon’s Website
Devon’s Twitter
Introducing: The Life of David Rhoiney

Show Notes:

Centralization & Institutional Corruption
The Evolving Nature of Resource Constraints
Why Theft of Fire Features Alien Technology
The Musk Dynasty
Architects vs Gardeners
Editing, Feedback & Beta-Readers
Audience Capture & Disagreeableness
“Money is a measure of fu*ks given”
Patronage & Intellectual Property in the Digital Era
Permissionless Writing
How to Become a High-Agency Character
Devon as Emperor of the World
MORE!

Books and Articles Mentioned:

Theft of Fire; by Devon Eriksen
The Ultimate Resource; by Julian Simon
The Moon Is a Harsh Mistress; by Robert A. Heinlein
The Population Bomb; by Paul R. Ehrlich
Zen and the Art of Motorcycle Maintenance; by Robert M. Pirsig
The Status Game: On Human Life and How to Play It; by Will Storr

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Econtalk

There's often a gap between the textbook treatment of statistics and the cookbook treatment--how to cook up the numbers when you're in the kitchen of the real world. Jeremy Weber of the University of Pittsburgh and the author of Statistics for Public Policy hopes his book can close that gap. He talks to EconTalk host Russ Roberts about how to use numbers thoughtfully and honestly.

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Artificial Intelligence Podcast

Key Takeaways * “The best businesses are forever assets.” – Bill Ackman * It is optimal to invest in businesses that have a low probability of getting disrupted * Price is what you pay; value is what you get * In investing, you can do very well if you avoid losing money and have a few great hits * Price matters: You can buy the best business in the world, but you will not earn a particularly attractive return if you overpay for it * It is best to invest in growing businesses that are easy to understand and that will generate cash over the long term * Progress compounds in a similar way that money compounds * Never invest money that you cannot afford to lose * “Harvard has become a place where free speech is not tolerated on campus, or at least free speech that’s not part of the accepted dialogue.” – Bill Ackman * Lowercase diversity, equity, and inclusion are good; it is the uppercase“DEI” ideology that is problematic * The only person who can cause you more harm than a thief with a dagger is a journalist with a pen * The current problem in politics is that the party system is not working properly; the parties are self-interested and are not incentivized to do what is best for the country * Technology will save us; we must return to a meritocratic world

Read the full notes @ podcastnotes.org

Bill Ackman is an investor who has led some of the biggest and controversial financial trades in history. He is founder and CEO of Pershing Square Capital Management. Please support this podcast by checking out our sponsors:
- LMNT: https://drinkLMNT.com/lex to get free sample pack
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- Eight Sleep: https://eightsleep.com/lex to get special savings
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Transcript: https://lexfridman.com/bill-ackman-transcript

EPISODE LINKS:
Bill's X: https://twitter.com/BillAckman
Pershing Square Holdings: https://pershingsquareholdings.com/
Pershing Square Foundation: https://pershingsquarefoundation.org
Neri Oxman conversation: https://www.youtube.com/watch?v=XbPHojL_61U
Books mentioned:
The Intelligent Investor: https://amzn.to/3ONnaZy
America's Cultural Revolution: https://amzn.to/3SDz1dY

PODCAST INFO:
Podcast website: https://lexfridman.com/podcast
Apple Podcasts: https://apple.co/2lwqZIr
Spotify: https://spoti.fi/2nEwCF8
RSS: https://lexfridman.com/feed/podcast/
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SUPPORT & CONNECT:
- Check out the sponsors above, it's the best way to support this podcast
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- LinkedIn: https://www.linkedin.com/in/lexfridman
- Facebook: https://www.facebook.com/lexfridman
- Medium: https://medium.com/@lexfridman

OUTLINE:
Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) - Introduction
(08:55) - Investing basics
(13:47) - Investing in music
(22:08) - Process of researching companies
(26:47) - Investing in restaurants
(32:16) - Investing in Google
(37:58) - AI
(43:13) - Warren Buffet
(45:22) - Psychology of investing
(54:53) - Activist investing
(1:04:41) - General Growth Properties
(1:20:57) - Canadian Pacific Railway
(1:28:21) - OpenAI
(1:32:32) - Biggest loss and lowest point
(1:47:21) - Herbalife and Carl Icahn
(2:04:11) - Oct 7
(2:10:42) - College campus protests
(2:29:09) - DEI in universities
(2:50:00) - Neri Oxman
(3:15:30) - X and free speech
(3:19:54) - Trump
(3:27:30) - Dean Phillips
(3:34:36) - Future

America's Cultural Revolution: How the Radical Left Conquered Everything

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LaBossiere Podcast

Delian Asparouhov is the co-founder, President and Chairman of Varda Space Industries, a company building spacecraft to manufacture materials in microgravity that are difficult or impossible to produce on Earth— starting with pharmaceuticals. He’s also a Partner at Founders Fund.

Previously, he was a principal at Khosla Ventures, head of growth at Teespring, and founder of a healthcare company called Nightingale. Delian is Bulgarian, attended MIT, and likes to ski and play soccer.

0:00 - Intro3:14 - How Does Innovation Happen?6:23 - Varda and the No Science Allowed Rule7:52 - A Primer on Solid State Microgravity Manufacturing18:25 - Space Industrialization, Trading Posts, and the Chinese and Portuguese Navies21:13 - Economic Incentives and Future Business Models in Space24:24 - SpaceX and The Costs of Mass to Orbit27:45 - Demand for Space Manufacturing and Varda at Scale33:44 - Manufacturing, Servicing, Machining, and Future Markets for Space36:42 - Incubating Companies40:33 - When Would Varda Have Been Started Otherwise?42:19 - The Hollywood Model of Startups45:20 - Future of Incubations47:47 - Media’s Role in Technology50:39 - What Media Inspired Varda’s Founding?52:38 - Talent, Culture, and Cementing Company Trajectory53:57 - Narratives and Talent Recruitment55:28 - Traits Delian Looks for in Founders57:38 - The ‘Why Now’ When Investing1:00:08 - Bring Non-Consensus and Right1:02:53 - Is Varda Consensus Yet?1:03:24 - Identifying Non-Consensus Opportunities1:05:12 - Lessons from Founding and Investing1:07:40 - What Skill Do You Wish You’d Developed Earlier?1:10:11 - Immigrant Mentality1:11:24 - Less Obvious Reasons for Success1:12:55 - On Speed1:14:23 - What Should More People Be Thinking About?

🎙️More Episodes🎙️YouTube: https://bit.ly/3QDLQFtApple: https://apple.co/478Be6MSpotify: https://spoti.fi/3sfiFiE

📲Socials📲

Twitter: https://twitter.com/adlabossiere

Linkedin: https://www.linkedin.com/in/alexlabossiere/

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Jordan B Peterson Podcast

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Dr. Jordan Peterson speaks with author, teacher, and prior hostage negotiator Chris Voss. They discuss the necessity of prioritizing needs and wants, how to navigate the job market to fit your best potential, how and why to go after a raise, the primacy of invitational collaboration over compelled, and how Voss succeeded in many real-world hostage negotiations.

Chris Voss has served as the lead international kidnapping negotiator for the Federal Bureau of Investigation (FBI), the hostage negotiation representative for the National Security Council’s Hostage Working Group, and the lead Crisis Negotiator for the NYC division of the FBI. Chris was a member of the New York City Joint Terrorist Task Force for 14 years, a recipient of the Attorney General’s Award for Excellence in Law Enforcement, and the FBI Agents Association Award for Distinguished and Exemplary Service. Chris has taught business negotiation courses at the University of Southern California, Georgetown University, and Harvard University. He has also guest lectured at Northwestern University and at schools abroad. Currently, Chris works with Insite Security as their Managing Director of the Kidnapping Resolution Practice.

Links -

2024 tour details can be found here https://jordanbpeterson.com/events

Peterson Academy https://petersonacademy.com/

For Chris Voss:

On Instagram https://www.instagram.com/thefbinegotiator/?hl=en

On X https://twitter.com/fbinegotiator?lang=en

Sign up for Chris Voss’s Newsletter https://www.blackswanltd.com/no-oriented-questions

“Never Split the Difference: Negotiating As If Your Life Depended On It” (book) https://www.amazon.com/Never-Split-Difference-Negotiating-Depended/dp/0062407805

Learn to negotiate with the Black Swan Group https://www.blackswanltd.com/

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Rich Roll Podcast

Key Takeaways * Check out the episode page

Read the full notes @ podcastnotes.org

Harvard’s renowned “Mother of Mindfulness,” Dr. Ellen Langer offers an insightful assessment: the root cause of global challenges lies in mindlessness. With an illustrious forty-five-year career and the distinction of being the first woman to attain psychology tenure at Harvard. Her extensive work spans diverse topics, including the illusion of control, mindful aging, stress, decision-making, and health, challenging the conventional mind-body dualism in Western medicine.In her latest book, The Mindful Body: Thinking Our Way to Chronic Health, Dr. Langer delves into the transformative potential of mindfulness for improving health. This conversation dismantles the separation between mind and body, exploring the concept of mind-body unity. She dissects the power of belief, dispels the illusion of control, and offers a novel perspective on decision-making and manipulation. The discourse extends to the psychological construct of fatigue, demonstrating how mindfulness positively influences physical endurance.Advocating for a paradigm shift, Dr. Langer encourages liberating ourselves from past experiences and conventional wisdom. This transformative mindset, she asserts, unlocks untapped potential, fostering increased agency and empowerment. The discussion reveals intricate connections between the mind and body, providing practical tips and cutting-edge research to empower individuals to take control of their health and achieve enhanced well-being.

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Huberman Lab

Key Takeaways * Check Out the Huberman Lab Podcast Episode Page & Show Notes * Last week’s episode: The Science of MDMA & Its Therapeutic Uses: Benefits & Risks. Read more here

Read the full notes @ podcastnotes.org

In this episode, my guest is Tim Ferriss — a five-time #1 New York Times bestselling author, technology investor and host of the iconic podcast, The Tim Ferriss Show. We discuss Tim’s process of exploration, experimentation and mastery — themes that have spanned his career that have placed him on the cutting-edge of many important fields. Tim explains what questions to ask when approaching any new endeavor in order to maximize success. He also explains how to incorporate structure and playfulness into skill and knowledge mastery, how to find and work with mentors, the key importance of location and networks in creating truly impactful things. We also discuss Tim’s philanthropic efforts to support research on psychedelics for the treatment of mental health challenges and we discuss his latest creative endeavors. This episode should be of interest to a wide range of listeners, as Tim’s mastery and wisdom spans athletic and mental pursuits, business, media, technology and the arts. What distinguishes Tim is his ability to thoughtfully deconstruct these processes in order to teach others how to do the same.

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

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Timestamps

(00:00:00) Tim Ferriss

(00:04:08) Sponsors: Maui Nui, LMNT, Levels

(00:07:43) 4-Hour Body & Development Mindset

(00:15:22) Origins of Good Ideas

(00:20:06) Writing & Structured Thinking

(00:27:58) Writing, Night Owls

(00:33:06) Sponsor: AG1

(00:34:21) Investigating Outliers; Social Media & Smartphones

(00:40:37) Scientific Literacy, Randomized Clinical Trials

(00:45:09) Supplement & Experiment Fails; Cold Exposure & Hyperthermia

(00:50:46) Slow Carb Diet & Adherence

(01:03:35) Morning Protein Intake; Fasting

(01:08:48) Sponsor: InsideTracker

(01:09:53) Power of Place; Building Your Network & Volunteering

(01:21:43) Developing Skills; Examining Motivation & Good Questions; Simplicity

(01:33:32) Early Psychedelic Exploration, Depression

(01:45:38) Psychedelic Research & Mental Health Funding

(01:59:00) Saisei Foundation, Journalism Fellowship, Law & Education

(02:08:22) Transcranial Magnetic Stimulation (TMS), Psychedelics

(02:13:28) Meditation, Transcendental Meditation, Nature

(02:18:50) Extended Nature Retreats & Integration Period; “Generative Drive”

(02:28:05) Mentors

(02:34:53) Mind & Attention Allocation, Social Media, Boredom

(02:44:12) Cockpunch

(03:00:23) Suicide & Depression, Sexual Abuse, Vulnerability

(03:14:22) Making Meaning from Suffering

(03:19:32) Role Identity, Future

(03:27:38) Parenthood, Animals & Training

(03:32:21) Podcasting, Experimentation

(03:36:52) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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The Danny Miranda Podcast

Key Takeaways * The purpose of meditation for Robert Greene was not to renounce worldly ambitions but to find self-awareness and connect ambitions to his true self * Lessons from 12+ years of meditation: + Robert’s meditation practice involves daily sessions of Zen meditation, sitting for 35-45 minutes in complete silence + Meditation is a source of creativity as it taps into his unconscious and brings forth new and unexplored ideas + The mind becomes like an empty, blue sky—free from hindrances and fixed ideas—through meditation + He emphasizes the importance of connecting ambition to something deep within oneself, rather than pursuing empty or external goals * Those who constantly seek distractions instead of facing boredom weaken their ability to handle resistance * Writers in their 20s often make the following mistakes: + Poor punctuation, spelling, and grammar skills + Underestimating the importance of writing as a skill + Assuming that writing doesn’t require effort or practice + Focusing on their ego rather than effective communication + Using clever phrases and puns without conveying meaningful content * Writing is not about self-expression but about communicating effectively with others * Developing empathy involves redirecting narcissism and self-love toward others and being genuinely interested in understanding their perspectives * Reading people’s emotions and moods, rather than trying to read their minds, is crucial in understanding and connecting with them * Those who have a clear sense of their unique destiny from an early age tend to have more success and power in life * Success, for Robert, is the feeling of freedom where he doesn’t have bosses, people pressuring him, or limitations on what he can write about * The experience of being in a coma, waking up, and realizing how close he came to death made death more than just an intellectual idea—it became a physical presence * He always prioritized gaining life experiences and finding things interesting over monetary considerations * “The 48 Laws of Power” continues to sell well because it transcends specific periods and remains applicable to the current power dynamics, especially with the rise of social media and the internet * He does not aim to create sequels or repeat past successes for the sake of making money but instead focuses on exploring new areas and ideas * Robert is currently working on a book about the sublime, which builds upon the final chapter of “The Laws of Human Nature” and “The 50th Law” (co-authored with 50 Cent) that touched on the subject * Robert suggests a challenge for listeners to spend five minutes every day questioning thoughts, feelings, desires, and motivations instead of assuming that everything is known

Read the full notes @ podcastnotes.org

Robert Greene is a writer. His books have sold millions of copies (including The 48 Laws of Power).

In this conversation, we spoke about what new writers get wrong, valuing experiences over money, why his ideas have stuck for 25+ years, developing empathy, and the role of meditation in his own life.

(0:00) Intro

(1:58) Ancient Greece & 17th Century France

(6:55) Avoiding Yes Men

(10:53) Following Up On Success

(13:10) Lessons From 12+ Years of Meditation

(27:58) Importance Of Boredom

(36:00) What Do Most Writers In 20s Get Wrong?

(40:21) Developing Empathy

(46:38) The Voice

(52:28) Do People’s Problems Stick To Robert?

(54:12) Success = Freedom

(56:08) Death

(1:06:00) Ryan Holiday

(1:10:01) Valuing Experiences Over Money

(1:14:45) Longevity Of Ideas

(1:17:54) Robert’s Next Project

(1:20:04) Challenge

Robert’s Links

Website: https://powerseductionandwar.com

Twitter: https://twitter.com/robertgreene

Instagram: https://www.instagram.com/robertgreeneofficial

My Links

🎙 Podcast: https://anchor.fm/dannymiranda

🎥 YouTube: https://youtube.com/dannymiranda

🐣 Twitter: https://twitter.com/heydannymiranda

📸 Instagram: https://instagram.com/heydannymiranda

🕺 TikTok: https://tiktok.com/@heydannymiranda

The 50th Law (The Robert Greene Collection)

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Founders ✓

Claim

Key Takeaways * “The difference between one advertisement and another, when measured in terms of sales, can be as much as nineteen to one.” – David Ogilvy * Pay peanuts and you get monkeys * “I admire people who work with gusto. If you don’t enjoy what you are doing, I beg you to find another job. Remember the Scottish proverb: Be happy while you are living because you are a long time dead.” – David Ogilvy * The most important thing you will decide is what benefit to promise * “You are not advertising to a standing army. You are advertising to a moving parade.” – David Ogilvy * Most successful careers are built on isolated incidents * Study the great work that came before you * “I have come to the conclusion that the top man has one principal responsibility: to provide an atmosphere in which creative mavericks can do useful work.” – David Ogilvy * Tolerate genius and do not strangle the goose that lays the golden egg * Talent is most likely found among non-conformists, dissenters, and rebels * “In the best companies, promises are always kept, whatever it may cost in agony and overtime.” – David Ogilvy

Read the full notes @ podcastnotes.org

What I learned from reading Confessions of an Advertising Man by David Ogilvy.

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(4:15) When Fortune published an article about me and titled it: "Is David Ogilvy a Genius?," I asked my lawyer to sue the editor for the question mark.

(4:45) The people who built the companies for which America is famous, all worked obsessively to create strong cultures within their organizations. Companies that have cultivated their individual identities by shaping values, making heroes, spelling out rites and rituals, and acknowledging the cultural network, have an edge

(5:30) We prefer the discipline of knowledge to the anarchy of ignorance. We pursue knowledge the way a pig pursues truffles. A blind pig can sometimes find truffles, but it helps to know that they grow in oak forests.

(5:48) We hire gentlemen with brains.

(6:16) Only First Class business, and that in a First Class way.

(6:25) Search all the parks in all your cities; you'll find no statues of committees.

(9:45) Buy Ogilvy on Advertising

(10:45) One decent editorial counts for a thousand advertisements. + You simply cannot mix your messages when selling something new. A consumer can barely handle one great new idea, let alone two, or even several. — Against the Odds: An Autobiography by James Dyson (Founders #300)

(15:22) It was inspiring to work for a supreme master. M. Pitard did not tolerate incompetence. He knew that it is demoralising for professionals to work alongside incompetent amateurs.

(16:66) You have to be ruthless if you want to build a team of A players. It's too easy, as a team grows, to put up with a few B players, and they then attract a few more B players, and soon you will even have some C players. The Macintosh experience taught me that A players like to work only with other A players, which means you can't indulge B players.

(18:12) In the best companies, promises are always kept, whatever it may cost in agony and overtime.

(18:33) I have come to the conclusion that the top man has one principal responsibility: to provide an atmosphere in which creative mavericks can do useful work.

(19:38) I admire people who work hard, who bite the bullet.

(19:58) I admire people with first class brains.

(20:23) I admire people who work with gusto. If you don't enjoy what you are doing, I beg you to find another job. Remember the Scottish proverb, "Be happy while you're living, for you're a long time dead."

(20:50) I admire self-confident professionals, the craftsmen who do their jobs with superlative excellence.

(21:40) The best way to keep the peace is to be candid.

(23:18) That’s been the most important lesson I’ve learned in business: that the dynamic range of people dramatically exceeds things you encounter in the rest of our normal lives—and to try to find those really great people who really love what they do. — Make Something Wonderful: Steve Jobs in his own words. (Founders #299)

(24:39) The Man Who Sold America: The Amazing (but True!) Story of Albert D. Lasker and the Creation of the Advertising Century by Jeffrey L. Cruikshank and Arthur W. Schultz. (Founders #206)

(25:09) Claude Hopkins episodes:

My Life in Advertising by Claude Hopkins. (Founders #170)

Scientific Advertising by Claude Hopkins. (Founders #207)

(25:47) Talent is most likely to be found among nonconformists, dissenters, and rebels.

(26:49) The majority of business men are incapable of original thinking because they are unable to escape from the tyranny of reason. Their imaginations are blocked.

(28:21) This podcast studies formidable individuals.

(31:40) Samuel Bronfman: The Life and Times of Seagram’s Mr. Sam by Michael R. Marrus. (Founders #116)

(37:47) I doubt whether there is a single agency (or company) of any consequence which is not the lengthened shadow of one man.

(39:51) Don't bunt. Aim out of the park. Aim for the company of immortals.

(40:13) Most big corporations behave as if profit were not a function of time.

When Jerry Lambert scored his first breakthrough with Listerine, he speeded up the whole process of marketing by dividing time into months. Instead of locking himself into annual plans, Lambert reviewed his advertising and his profits every month.

The result was that he made $25,000,000 in eight years, where it takes most people twelve times as long. In Jerry Lambert's day, the Lambert Pharmaceutical Company lived by the month, instead of by the year.

(41:30) The Mind of Napoleon: A Selection of His Written and Spoken Words edited by J. Christopher Herold. (Founders #302)

(41:36) I am an inveterate brain picker, and the most rewarding brains I have picked are the brains of my predecessors and my competitors.

(43:27) We make advertisements that people want to read. You can't save souls in an empty church.

(44:05) You aren't advertising to a standing army; you are advertising to a moving parade.

(45:13) The headline is the most important element in advertisements.

(47:47) Runnin' Down a Dream: How to Succeed and Thrive in a Career You Love by Bill Gurley

(48:15) Set yourself to becoming the best-informed man in the agency on the account to which you are assigned.

If, for example, it is a gasoline account, read text books on the chemistry, geology and distribution of petroleum products. Read all the trade journals in the field. Read all the research reports and marketing plans that your agency has ever written on the product. Spend Saturday mornings in service stations, pumping gasoline and talking to motorists. Visit your client's refineries and research laboratories. Study the advertising of his competitors. At the end of your second year, you will know more about gasoline than your boss.

Most of the young men in agencies are too lazy to do this kind of homework. They remain permanently superficial.

Subscribe to listen to Founders Premium — Subscribers can ask me questions directly and listen to Ask Me Anything (AMA) episodes.

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“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

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The Man Who Sold America: The Amazing (but True!) Story of Albert D. Lasker and the Creation of the Advertising Century

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Starting Greatness with Mike Maples

When he was a little boy growing up in Sweden, Daniel Ek was obsessed with two things: the binary realm of computers and the artistry of music. As a young adult, he combined his love for both by co-founding Spotify, which became the global standard-bearer for streaming, Spotify now has more than 500 million users per month. In this episode, Mike Maples, Jr of FLOODGATE interviews Daniel Ek to break down the importance of recognizing technology infections, securing the perfect niche to secure early product-market fit, and how creating something radically different changed the music industry while redefining consumer listening habits.

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Huberman Lab

Key Takeaways * Check Out the Huberman Lab Podcast Episode Page & Show Notes * Curious about Andrew Huberman’s recipe for good sleep? Read more here

Read the full notes @ podcastnotes.org

In this episode, I discuss Methylenedioxymethamphetamine (MDMA), which is also commonly known as “ecstasy” or “molly,” including how it works in the brain to cause short- and long- term-shifts in emotional processing and its clinical applications for the treatment of post-traumatic stress disorder (PTSD), alcohol and other substance-use addictions. I discuss the neuronal mechanisms for how MDMA elevates mood, empathy, motivation, social engagement, and empathy, and reduces “threat detection” and how these effects can synergistically support talk therapy. I also explain the ongoing debate about the potential neurotoxicity of MDMA, myths about the origins and treatments for post-MDMA “crash,” the evolving legal landscape around MDMA use for clinical purposes, and I caution recreational users about the extremely dangerous additives (e.g., fentanyl) now commonly found in black market MDMA. This should be of interest to those curious about MDMA, neuropharmacology, the origins of emotional processing in the brain, empathy, PTDS, neuroplasticity, mental health and psychiatry.

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

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Momentous: https://livemomentous.com/huberman

Timestamps

(00:00:00) MDMA “Ecstasy”

(00:04:37) Sponsors: Helix Sleep, ROKA, HVMN

(00:08:18) MDMA History & Synthesis; Legality

(00:14:45) MDMA, Methamphetamine (Meth), Dopamine & Serotonin

(00:23:30) MDMA vs Psychedelics vs Ketamine

(00:26:54) MDMA & Serotonin 1B Receptor, Subjective Feelings, Trauma

(00:33:36) Sponsor: AG1 (Athletic Greens)

(00:34:51) Amygdala & Threat Detection, Pro-Social Behavior, MDMA Dosages

(00:45:48) Interoception, MDMA & Post-Traumatic Stress Disorder (PTSD)

(00:52:36) Long-Term Effects, Threat Detection & PTSD

(00:56:14) MDMA, Social Connection & Empathy; Meth, SSRIs

(01:06:10) Sponsor: LMNT

(01:07:22) Oxytocin & MDMA

(01:16:10) Safety & Neurotoxicity; Recreational Use, Caffeine & Fentanyl

(01:26:36) Is MDMA Neurotoxic?; Poly-Pharmacology, Body Temperature

(01:37:07) Post-MDMA “Crash”, Prolactin & P‑5‑P

(01:43:07) PTSD & Trauma; Talk Therapy, SSRIs

(01:54:09) PTSD Treatment: Talk Therapy + MDMA

(02:02:46) MDMA & Addiction; Dissociative PTSD & Empathy

(02:09:47) Side-Effects?, MDMA Efficacy & Legality

(02:15:22) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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My First Million

Key Takeaways * Check out My First Million Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Shaan's Free Workshop --> http://bit.ly/3INb6EV

Episode 462: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk with Alex Hormozi (@AlexHormozi), founder of GymLaunch and Acquisition.com, about what he regrets about selling his business and why he's pumped about starting a new one, how he spends his money, and his secret to a successful marriage.

Want to see more MFM? Subscribe to the MFM YouTube channel here.

Check Out Shaan's Stuff:

Power Writing Course
Daily Newsletter

Check Out Sam's Stuff:

Hampton
Ideation Bootcamp
Copy That

Show Notes:

(04:00) - Upsides and Downsides of being famous

(10:45) - Status of Acquisition

(31:55) - Regrets about selling

(41:30) - Why do people get mega rich?

(58:20) - Who do you admire?

(01:04:40) - Secrets of successful marriages

(01:13:30) - What products/brands are you obsessed with?

(01:18:10) - What are you doing with your money?

Links:

Acquisition
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Modern Wisdom

Key Takeaways * Tracking how you spend your time allows you to optimize your life; it becomes very apparent where you waste time and where you should be spending more of it * Be excited about becoming a better version of yourself * Take the time to design the life you want to live, and then take the steps to grow into it * Create disciplined habits to reduce the effort required to stick with them; eventually, these habits become intuitive and effortless * Immediately take action on emergent friction, eliminate it, and get back into harmony * The joy of life is living in a balanced and harmonious state, and continually evolving into your limitless potential * You must reflect so you can decide which parts of your life must change or adapt * Your ability to spend your time on the things that you want will be dictated by the amount of money you need to live the life you want to live * “You don’t ever want to ‘get somewhere.’ You want to be there, always.” – Rob Dyrdek

Read the full notes @ podcastnotes.org

Rob Dyrdek is a former professional skateboarder, entrepreneur, reality TV star, venture capitalist and a producer.

What if you tracked every second of your life? What if you dialled in every process, calorie, action and thought to facilitate your best performance? What if you manifested a Playboy wife out of thin air by just wanting her a lot? Today we get to find out.

Expect to learn about Rob’s journey from a small-town kid to a globally successful entrepreneur, his rigorous system for intentionality and productivity, the crucial factors that propelled him towards success, the system behind Rob’s meticulous tracking of his daily activities, how Rob met his dream wife, Rob's bulletproof investment strategy, his thoughts on the personal development space and much more...

Sponsors:

Get over 37% discount on all products site-wide from MyProtein at https://bit.ly/proteinwisdom (use code: MODERNWISDOM)

Get 20% OFF with our code MODERNWISDOM at https://calderalab.com/modernwisdom to unlock your youthful glow and be ready for summer with Caldera + Lab!

Get 20% discount on House Of Macadamias’ nuts at https://houseofmacadamias.com/modernwisdom (use code MW20)

Extra Stuff:

Check out Rob's website - https://dyrdekmachine.com/

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Huberman Lab

Key Takeaways * Check Out the Huberman Lab Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

In this episode, my guest is Mary Helen Immordino-Yang, EdD, a professor of education and psychology at the University of Southern California (USC) who has done groundbreaking research on emotions, self-awareness and social interactions and how these impact the way we learn and change across our lifespan. She explains how an understanding of emotions can be leveraged to improve learning in kids and in adults, and how the education system should be altered to include new forms of exploration, rules, and emotional and social contexts to facilitate better learning and to include more diverse learning (and teaching) styles. This episode ought to be of interest to anyone interested in how we learn, human development in children and adults, as well as those generally interested in education, psychology or neuroscience.

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

AG1: https://athleticgreens.com/huberman

Eight Sleep: https://eightsleep.com/huberman

HVMN: https://hvmn.com/huberman

ROKA: https://roka.com/huberman

InsideTracker: https://insidetracker.com/huberman

Momentous: https://livemomentous.com/huberman

The Brain Body Contract

https://hubermanlab.com/tour

Timestamps

(00:00:00) Dr. Mary Helen Immordino-Yang

(00:02:11) Sponsors: Eight Sleep, HVMN, ROKA

(00:05:54) Inspiration, Awe & Story

(00:09:59) Brain-Body, Narratives

(00:15:58) Emotions, Durability & Lifespan

(00:21:47) Conjuring Stories, Historical Context & Emotion

(00:32:16) Sponsor: AG1

(00:33:30) Hierarchal Emotion Organization, Default Mode Network, Story & Emotion

(00:46:24) Emotional Development & Lifetime

(00:57:13) Narrative & Genocide; Checking Assumptions & Mental Flexibility

(01:05:22) Social Media, Cognitive Dissonance

(01:09:52) Education, Deconstructing Beliefs & Curiosity

(01:17:22) Sponsor: InsideTracker

(01:18:32) Emotion & Learning; Constructing Meaning

(01:28:59) Good Teachers & Curiosity

(01:33:25) Inter-disciplinary Education; Development & Culture

(01:50:58) Idea Exploration, Tolerance

(01:56:53) Reframing Education, Deconstructing Assumptions

(02:03:28) Safety, Creativity & Default Mode Network

(02:12:15) Civic Discourse & Education; Deconstructing Ideas

(02:27:31) “Mirror” Neurons, Shared Social Experiences

(02:35:49) Cold Exposure & Sickness; Role of Education

(02:38:51) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Drive with Dr. Peter Attia

Key Takeaways * Check out The Drive Episode Page & Show Notes

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Sign Up to Receive Peter’s Weekly Newsletter

Tommy Wood is an Assistant Professor of Pediatrics at the University of Washington, where he studies brain injury and how lifestyle choices and environmental factors contribute to brain health, cognitive function, and chronic disease. In this episode, Tommy delves into the complexities of age-related cognitive decline and explores interventions to counteract it. Drawing from his experience working with Formula 1 drivers, he highlights the connection between cognitive function and the right type of demands and training leading to improvement. Next, he explores the various theories on the different types of pathology in dementia and neurodegeneration. He makes the case that a large fraction of dementia is preventable through lifestyle choices and nutrient status, and provides an in-depth overview of interventions and supplements that support cognitive function. Finally, he provides a comprehensive overview of head injuries, including concussions and traumatic brain injuries (TBIs), discussing symptoms, how to mitigate damage following an incident, and long-term management.

We discuss:

Tommy’s professional work, unique skill sets, and interests [3:00];
Age-related decline in cognitive function and memory [5:45];
Improving brain function with the right level and type of demand [20:15];
Formula 1 as a model for how to perform under high cognitive demand and how to increase multitasking capacity [31:30];
Advice for the person reaching middle life looking to mitigate cognitive decline [37:45];
Tasks and activities that support and improve cognitive function [45:30];
Neuropathology of Alzheimer’s disease: exploring the role of amyloid and tau proteins [49:30];
Why Tommy believes dementia research funding should be focused on environmental and lifestyle-based risk factors [1:05:15];
Benefits of lowering homocysteine and boosting omega-3’s, and evidence-based supplements that support cognitive function [1:09:00];
A unifying theory of dementia [1:20:45];
How muscular strength can help with both the prevention and survivability of dementia [1:24:15];
Head injuries: comparing concussions against traumatic brain injuries (TBIs), mitigating the damage after an incident, and the long-term management of head injuries [1:29:15];
Is hyperbaric oxygen treatment helpful after a TBI? [1:45:45];
Supplements that aid recovery from a TBI: creatine, DHA, and choline [1:49:30];
Demands faced by F1 drivers, and testing interventions to improve their performance [1:57:30]; and
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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Infinite Loops

Key Takeaways * Hypnosis has a way of effectively communicating with the self-conscious and is the most efficient way to upgrade the mental software that we all have * The hypnotic state is a state of accelerated learning or relaxed focused attention where a person is more suggestible, which means it is easier for them to change the way they think or feel about something * Hypnosis is not widely used due to misconceptions, lack of public awareness, and lack of consistent training standards * It is more profitable to treat symptoms than to treat root causes; this creates perverse incentives for the healthcare industry * The subconscious mind is more likely to absorb negative suggestions than positive suggestions * Secondary gains can obstruct progress, meaning the person gets a benefit from having the problem so they subconsciously sabotage their efforts to resolve it * One of the most effective ways to change the behavior is to change the way they think about it * “World peace starts with inner peace. If you want to make the world a better place, you got to make yourself a better place.” – Todd Goodwin

Read the full notes @ podcastnotes.org

Todd Goodwin is the founder of Goodwin Hypnosis, a hypnosis center based in North Carolina. He is a Board Certified Fellow of the National Guild of Hypnotists, a designation earned by only one in every 500 hypnotists.

As well as working with thousands of clients since opening Goodwin Hypnosis in 2007, Todd has co-facilitated hypnosis certification courses, created a book and accompanying 30-day hypnosis system designed to stop people from smoking, and given numerous presentations on hypnosis to physicians, students, and medical staff.

Todd joins the show to discuss some of the common myths & misconceptions around hypnosis.

Important Links:

Goodwin Hypnosis
Goodwin Hypnosis’ YouTube
The Thinker and the Prover
Our episode on Dr John Sarno
The Six Stage Model of Behaviour Change

Show Notes:

Hypnosis in our everyday lives
Why isn’t hypnosis more widely used?
“I don’t want someone in my head”
“I can’t be hypnotized”
Targeting the root causes of behavior
Tension between the conscious & the unconscious
How secondary gains can obstruct progress
How to clear root fear
Using language to elicit change
Be curious about yourself; remember that you are worthy of love
MORE!

Books Mentioned:

Healing Back Pain; by John E. Sarno
Influence: Science and Practice; by Robert Cialdini
Frogs into Princes: Neuro Linguistic Programming; by Richard Bandler and John Grinder

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Huberman Lab

Intro * Check Out Huberman Lab Premium Channel

Read the full notes @ podcastnotes.org

Welcome to a preview of the seventh Ask Me Anything (AMA) episode, part of the Huberman Lab Premium subscription.
The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.
Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium.
Timestamps
(00:00:00) Introduction
(00:01:45) Is It Possible to Get a Cold or Sick From Deliberate Cold Exposure?
(00:20:02) Huberman Lab Premium

In the full AMA episode, we discuss:

How Can You Increase Rapid Eye Movement (REM) Sleep?

What Experiment(s) Would You Like to Undertake in Regard to Physical or Mental Performance?

Articles

Immune system of cold-exposed and cold-adapted humans

Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

The Effects of Sleep Extension on the Athletic Performance of Collegiate Basketball Players

Sleep extension improves serving accuracy: A study with college varsity tennis players

The impact of extended sleep on daytime alertness, vigilance, and mood

Title Card Photo Credit: Mike Blabac
Disclaimer

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Huberman Lab

Key Takeaways * Check Out the Huberman Lab Podcast Episode Page & Show Notes * Can’t get enough of Andrew Huberman? Check out our member only collection packed with Huberman’s greatest tips

Read the full notes @ podcastnotes.org

In this episode, I explain how medications such as Adderall, Ritalin, Vyvanse and other stimulants work to increase focus and treat attention-deficit/hyperactivity disorder (ADHD). I explain the brain circuits involved in focus and the key roles dopamine and norepinephrine play in their regulation. Then I explain how stimulants such as Adderall and Vyvanse can increase focus and reduce hyperactivity in kids or adults with ADHD, and how and why Ritalin and other medications (e.g., Modafinil, Guanfacine) may work better for some. I explain the long-term effects of ADHD medications on height, cardiovascular health, hormones, predisposition to addiction and psychosis, and whether these treatments can be used and then stopped. I also discuss the immense individual variation in dosage sensitivity for these medications and the negative side-effects that occur from recreational use. This episode ought to benefit anyone with ADHD, their parents, those on ADHD medications or anyone curious about how these medications work.

For the full show notes, visit hubermanlab.com.

Thank you to our sponsors

AG1: https://athleticgreens.com/huberman

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Momentous: https://www.livemomentous.com/huberman

The Brain Body Contract

https://hubermanlab.com/tour

Timestamps

(00:00:00) Stimulants & Attention-Deficient/Hyperactivity Disorder (ADHD)

(00:03:21) Sponsors: Maui Nui, ROKA, HVMN

(00:06:35) The Brain-Body Contract

(00:07:22) Attention, Prefrontal Cortex & ADHD

(00:16:27) Stimulants “Sympathomimetics”

(00:21:29) Adderall, Dopamine & Norepinephrine

(00:25:58) Sympathomimetics, Dopamine & Norepinephrine

(00:31:05) Sponsor: AG1

(00:32:20) Vyvanse is Timed-Release D-Amp

(00:36:36) Ritalin, Concerta

(00:40:10) Dopamine & “Noise Reduction”; Norepinephrine & “Signal Amplification”

(00:45:28) ADHD: Focus, Hyperactivity & Impulsivity; Drug Selection & Dose

(00:50:57) How do Stimulants ‘Calm’ ADHD?

(00:54:480 Neuroplasticity & Neuromodulators

(00:58:06) Kids, ADHD Diagnosis & Treatment; Predispose Addiction?

(01:04:02) Sponsor: InsideTracker

(01:05:12) ADHD Medications: Individuality, Doses, Tapering & Long-Term Use

(01:13:28) Medication & Long-Term Effects: Height, Cardiovascular Risk, Alcohol

(01:19:32) Cortisol & Hormones

(01:27:45) Psychosis & Addiction; Methamphetamine

(01:38:20) Recreational Use, Addiction & Psychosis; Habituation

(01:42:30) Drug Holidays; Ritalin & Long-Term Effects

(01:45:35) Modafinil, Armodafinil; Side-Effects

(01:53:03) Guanfacine, Alcohol

(01:58:03) ADHD Medications

(02:00:26) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Huberman Lab

Key Takeaways * “Psychedelics seem to give people access to a better version of self.” – Dr. Andrew Huberman + Possibly in part because of ego dissolution properties of psychedelics (versus ego inflation properties of drugs like cocaine) * Psychedelics can reveal something about the mind that can’t be revealed otherwise – maybe because it’s masked, unconscious, or below the threshold of awareness * Psilocybin changes the brain in a way that allows new ideas and new forms of learning to occur * More classic psychedelics like psilocybin allow you to dive deeper into the uncomfortable in a way that MDMA does not + MDMA is a strong empathogen for self and others * The setting plays a huge role in the outcomes of psychedelic studies; features include: strategic music, eye mask, 2 non-using professionals + 1 client/patient, 1-3 sessions spread across a few weeks, integration with psychotherapy (talk therapy) * Despite the massive attention it’s gotten, the evidence doesn’t currently support any benefits of microdosing – just macrodosing under clinical supervision * The psychedelic renaissance has come a long way! From fringe science and taboo culture to a huge draw for donors and openly discussed and researched in academic settings

Read the full notes @ podcastnotes.org

In this episode, my guest is Robin Carhart-Harris, PhD, distinguished professor of neurology and psychiatry at the University of California, San Francisco. He is one of leading researchers in the study of how psychedelics such as psilocybin, LSD and DMT can change the human brain and in doing so, be used to successfully treat various mental health challenges such as major depression, anorexia, obsessive-compulsive disorder (OCD) and addiction. He explains how psilocybin induces sustained changes in adaptive brain wiring and cognition. We discuss the key components of safe and effective psychedelic journeys, the role of hallucinations, the use of eye-masks to encourage people to “go internal,” and music, as well as what effective therapist support consists of before, during and after the session (also known as integration). We discuss micodosing vs. macrodosing and how researchers control for placebo effects in psychedelic research. We also discuss the current legal landscape around psychedelic therapies. Psychedelic therapies are fast emerging as powerful and soon-to-be mainstream treatments for medical health disorders, but they are not without their risks. As such, this episode ought to be of use to anyone interested in brain plasticity, mental health, psychology or neuroscience.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Eight Sleep: https://eightsleep.com/huberman
Levels: https://levels.link/huberman
HVMN: https://hvmn.com/huberman
LMNT: https://drinklmnt.com/huberman
Momentous: https://www.livemomentous.com/huberman
The Brain Body Contract
https://hubermanlab.com/tour
Timestamps
(00:00:00) Dr. Robin Carhart-Harris
(00:02:12) Sponsors: Eight Sleep, Levels, HVMN
(00:05:41) The Brain-Body Contract
(00:06:31) Origin of the Word: “Psychedelics”; Pharmacology
(00:12:05) Psychedelics & Revealing the Unconscious Mind, Psychotherapy
(00:17:32) Microdosing
(00:26:08) Psilocybin vs. Magic Mushroom Doses
(00:28:28) “Psychedelic-Therapy”, Music
(00:35:12) Sponsor: AG1 (Athletic Greens)
(00:36:26) Psychedelic Journey: “Trust, Let Go, Be Open”
(00:43:01) Negative Emotions, Fear & Psychedelics
(00:46:21) Global Functional Connectivity, Serotonin 2A Receptor; Subjective Experiences
(00:52:33) Pharmacology: Therapeutics without Psychedelic Effects; SSRIs
(00:58:45) Psilocybin & Depression; Long-Term Effects: Connectivity & Neuroplasticity
(01:09:14) Sponsor: LMNT
(01:10:26) Psilocybin Therapy & Anorexia
(01:12:56) Integration Phase & Psychedelic-Therapy; Meditation
(01:19:50) First-Time Psychedelic Use, “Entropic Brain Effect”, Neuroplasticity, Cognition
(01:30:16) Fibromyalgia & Psychedelic Treatment; MDMA Therapy & “Inner Healer”
(01:38:55) Placebo Response & Psychedelic Therapy
(01:41:39) LSD & Psychedelic-Therapy, Micro-Dose
(01:48:19) Combination Psilocybin-MDMA Therapy
(01:56:06) DMT “Rocketship” & Serotonin 2A Receptors; Ibogaine
(02:01:04) “Ego Dissolution”, Cocaine vs. Psychedelics; Relapses
(02:12:26) Psychedelics & Legal Landscape; Decriminalization
(02:17:54) MDMA, Trauma & Clinical Trials; Future Regulatory (FDA) Approval?
(02:23:25) Psilocybin & Current Clinical Trials
(02:28:41) Mental Health & Psychedelic Treatment, Safeguards, Paradigm Shift
(02:34:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Modern Wisdom

Key Takeaways * Check Out the Modern Wisdom Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Bryan Johnson is a founder of Braintree and Kernel, a futurist, biohacker and an author.

What does it take to achieve immortality? This is the frontier that Bryan Johnson is beginning to pioneer. Armed with a team of the world’s top researchers and an unlimited budget, he is using cutting edge science and technology to see just how long he can live for.

Expect to learn why Bryan chooses to be on a fully plant based diet, what Bryan Johnson’s full morning routine looks like, the optimal body fat percentage for living longer, why humans are addicted to self-destructive behaviour, why Bryan doesn’t fear death, why Bryan doesn’t use saunas or cold plunges for increasing his lifespan, what his training plan looks like and much more...

Sponsors:

Get 15% discount on Craftd London’s jewellery at https://craftd.com/modernwisdom (use code MW15)

Get 5 Free Travel Packs, Free Liquid Vitamin D and more from Athletic Greens at https://athleticgreens.com/modernwisdom (discount automatically applied)

Get 15% discount on Bon Charge’s red light therapy devices at https://boncharge.com/modernwisdom (use code: MW15)

Extra Stuff:

Check out Bryan's website - https://blueprint.bryanjohnson.co/

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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On Purpose with Jay Shetty

Key Takeaways * Check Out the Jay Shetty Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Today, I sit down with Kim Kardashian to talk about self compassion and self love. Kim talks about her experiences as a celebrity and an influencer, how she learned to love and take care of herself more so she can have more love and compassion for others, and the challenges of being a parent of four and running a business at the same time.

Kim Kardashian is an entrepreneur, business mogul, and producer. She first gained media attention in her appearances in the reality television series "Keeping Up with the Kardashians," which chronicles the personal and professional lives of her and her family members. Over the years, Kim Kardashian has built a successful brand, including beauty and fashion lines, and has become known for her influential social media presence.

You can order my new book 8 RULES OF LOVE at 8rulesoflove.com or at a retail store near you. You can also get the chance to see me live on my first ever world tour. This is a 90 minute interactive show where I will take you on a journey of finding, keeping and even letting go of love. Head to jayshettytour.comand find out if I'll be in a city near you. Thank you so much for all your support - I hope to see you soon.

What We Discuss:

00:00 Intro
03:55 When was the last time someone didn’t recognize you?
05:02 How often do you take a mental health check and have some time alone?
07:22 How do you manage a life in public with different personas?
09:38 Going out of your way to be of help and support someone in need
12:50 This is what genuine compassion can do for your personally and for others
16:25 Self work can be different for different people and that’s okay
18:02 Putting your own happiness first is a skill that can take time to learn
24:31 Surrounding yourself with people you trust is the best place to be in
29:05 With parenting, everyone says the days are long, the years are short
32:05 Parenting challenges is a lifetime commitment for every parent
36:32 Kids can ask difficult questions and this is how you can be more open to them
38:56 The journey of personal growth through helping other people
40:54 Kim explains that we all make mistakes and the second chance we get makes a huge difference
44:12 “I’ve never been hard on myself, but I am competitive with myself.”
47:03 How can positive peer pressure help you?
52:08 The warm welcoming presence always makes people comfortable and welcome
54:41 When you feel like you’re the worst mom, how do you cope?
01:00:10 Living a good life and being the best example for your kids
01:01:34 Kim on Final Five

Episode Resources

Kim Kardashian | Website
Kim Kardashian | YouTube
Kim Kardashian | Twitter
Kim Kardashian | Facebook
Kim Kardashian | TikTok
SKKN BY KIM
Skims

Want to be a Jay Shetty Certified Life Coach? Get the Digital Guide and Workbook from Jay Shettyhttps://jayshettypurpose.com/fb-getting-started-as-a-life-coach-podcast/

See omnystudio.com/listener for privacy information.

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Tetragrammaton with Rick Rubin✓Claim

Key Takeaways * Check Out the Episode Website

Read the full notes @ podcastnotes.org

Dr. Joe Dispenza
Dr. Joe Dispenza is a New York Times bestselling author and one of the most sought-after speakers in the world.

His expertise is the intersection of the fields of neuroscience, epigenetics, and quantum physics.

His books include You are the Placebo, Becoming Supernatural, Breaking the Habit of Being Yourself, and Evolve Your Brain.

Thank you to the sponsors that fuel our podcast and our team:

House of Macadamias

https://www.houseofmacadamias.com/tetra

Get a free box of Dry Roasted Namibian Sea Salt Macadamias + 20% off Your Order With Code TETRA

HVMN Ketone-IQ

https://hvmn.me/TETRA

Use code TETRA for 20% off at checkout

Leisure Craft Saunas

https://leisurecraft.com/

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Huberman Lab

Key Takeaways * Any cold exposure to the skin that you register as jarring or uncomfortable activates brown fat, increasing metabolism * Tip: don’t worry so much about the specific temperature, think more about the difference in temperature between your skin and the water * After drop: blood vessels constrict in the cold to keep organs healthy; once you get out of the cold, blood vessels dilate again but the surface is still cold so core body temperature drops and induces a shiver * Cycling heat and cold? End on cold for best results * “Cold is the most potent stressor activator of brown fat.” – Dr. Susanna Søberg * People who work outside (e.g., farmers) or were more active earlier in life will maintain higher levels of brown fat after age 40 * Long-term benefits of deliberate cold exposure: lower blood pressure, improve insulin sensitivity, improve metabolism, improve heart rate, better glucose balance * Cold & heat dose for optimal results: cold exposure 11 minutes per week, spread out across 2-3 sessions + 10-15 minutes per session (up to 30 minutes per week) + The goal is to keep the stimulus, a stimulus – you don’t want to build up the ability to hang out in cold for 11 minutes or sauna for an hour + There is a tipping point at which a good, hormetic stressor can feel like chronic stress to the body and you no longer receive additional healthy outcomes * Trouble tolerating cold exposure? You will still get all the benefits if you leave your hands out of the water, wear a cap and submerge up to the neck, and/or wear booties on your feet

Read the full notes @ podcastnotes.org

In this episode, my guest is Susanna Søberg, PhD. She earned her doctoral degree at the University of Copenhagen in Denmark, researching the effects of deliberate cold and deliberate heat exposure on metabolism and other aspects of human physiology. We discuss how cold or sauna can improve metabolism, cardiovascular and brain health, balance hormones, and decrease inflammation. Dr. Søberg discusses how deliberate cold protocols can improve glucose metabolism and insulin sensitivity and trigger release of neurotransmitters like dopamine and norepinephrine which enhance energy, mood, and focus. We compare cold showers and cold immersion, traditional and infrared saunas, and other variables. This episode provides actionable tools and answers to common questions about the use of deliberate cold and heat to improve health.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Plunge: https://plunge.com/huberman
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InsideTracker: https://insidetracker.com/huberman
Momentous: https://www.livemomentous.com/huberman
The Brain Body Contract
Tickets: https://hubermanlab.com/tour
Presale code: HUBERMAN
Timestamps
(00:00:00) Dr. Susanna Søberg
(00:03:23) Sponsors: Plunge, Maui Nui, Thesis
(00:06:49) The Brain-Body Contract
(00:07:40) Physiology in Uncomfortably Cold Environments
(00:12:05) Tool: Water Temperature, “Cold Shock” & Discomfort
(00:17:37) Cold Showers vs. Immersion in Water, Brown Fat
(00:22:11) Cold Receptors, Brown Fat & Temperature Homeostasis
(00:25:22) Shiver, “After Drop”, Healthy Stress
(00:31:08) Long-Term Health Benefits of Deliberate Cold Exposure
(00:35:48) Sponsor: AG1 (Athletic Greens)
(00:37:02) Blood Pressure & Heath
(00:38:26) Brown Fat, Insulin Sensitivity & Metabolism
(00:45:07) Temperature Regulation, Brown Fat vs. White Fat
(00:52:26) Cold Resilience, Scandinavia
(00:59:07) Sponsor: InsideTracker
(01:00:16) Winter Swimmers & Brown Fat; Discomfort
(01:10:28) Sex differences & Brown Fat, Cold-Adapted
(01:15:21) Diving Reflex & Parasympathetic Activation
(01:18:44) Tool: Deliberate Cold & Sauna Protocol
(01:23:11) Winter Swimmers, Shiver; Circadian Rhythm & Brown Fat
(01:31:14) Tool: Minimum Threshold for Cold & Heat; Sauna & Cardiovascular Health
(01:35:19) Tool: Maintaining Stimulus when Cold-Adapted; Shorter Sessions
(01:38:09) Cold Exposure, Sleep Quality, Clothing
(01:47:37) “Brown Fat Negative” & Shiver
(01:52:13) Cold & Heat, Inflammation Reduction
(01:55:40) Tool: “Soberg Principle”: End on Cold, Metabolism
(01:59:39) Cold Exposure: Fed or Fasted?
(02:00:32) Raynaud’s Syndrome; Hand/Feet Protection in Cold
(02:05:21) Tool: Headache & Cold Exposure; Head Submersion & Head Coverings
(02:11:29) Children & Hypothermia Risk
(02:17:16) Gender Differences & Cold Exposure
(02:19:57) Tool: Brief, Repeated Temperature Changes; Circadian Rhythm & Temperature
(2:27:53) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Jocko Podcast

Podcast Notes I * Podcast Notes Premium pulls out the signal from the noise so you can save time and learn more. * NEW – AI Powered Answers Engine * Premium members get unlimited access to Notes and Collections. * Collections integrate the key information on the most important aspects of life, business, and health. * They also provide a comprehensive set of lessons from the world’s greatest minds (Huberman, Naval, Elon, Chamath, and many more). * With Podcast Notes Premium, you get unlimited Podcast Notes browsing (over 1,000 notes since 2015), plus 100% ad-free content across all platforms. * You’ll also get early exclusive Notes on podcasts before they are published even! * Additional benefits include limited edition Podcast Notes magnet/stickers, entry into the Podcast Notes Premium community, priority Podcast Notes episode requests, and access to the Podcast Notes email archives (which contain every weekly email since 2015).

Read the full notes @ podcastnotes.org

Green Beret, Mike Glover outlines what it takes to be prepared for the worst.

Support this podcast at — https://redcircle.com/jocko-podcast/exclusive-content

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Art of Manliness

Key Takeaways * There are 63 national parks, but there are 424 national park sites * The most crowded time of the year is when every kid in the country is out of school; it is especially busy in the first few weeks of summer vacation * Months in advance, check if the park you plan to visit has a reservation system * There are only five parks that require a reservation to get into the park; however, most all require a reservation for camping * People will get their entire family on computers to sit there are refresh the park’s website hoping that one of them is lucky enough to get access to a reservation * “The single most important thing that we tell everybody is to get up early.” – Jeremy Puglisi * Yellowstone is a driving park more than it is a hiking park; it is a touring park * Jeremy’s favorite national park in Olympic National Park in Washington state and his favorite state park is Assateague in Maryland * Jeremy and Brett liked Grand Teton more than Yellowstone * Some of the best state parks: Custer State Park in South Dakota, Adirondack Park in New York State, Assateague State Park in Maryland, Snow Canyon State Park in Utah, and Jack London State Park in California * Nationally overlooked parks in the East: Acadia in Maine, Cape Cod national seashore in Massachusetts, Shenandoah in Virginia, New River Gorge in West Virginia, and Cape Hatteras national seashore in North Carolina * The most popular parks, such as Yellowstone, Yosemite, and the Grand Canyon, will be less busy during the shoulder months (March-April and September)

Read the full notes @ podcastnotes.org

America’s national parks are one of the country’s greatest treasures, and many people have it on their bucket list to visit one or more of these gems. But figuring out where to go and how to execute a national park experience can sometimes feel a little overwhelming.

Here to offer some really helpful advice on both visiting and camping in the national parks is Jeremy Puglisi, co-author, along with his wife Stephanie, of Where Should We Camp Next?: National Parks: The Best Campgrounds and Unique Outdoor Accommodations In and Around National Parks, Seashores, Monuments, and More. Today on the show, Jeremy walks us through how to navigate the complex reservation system some of the parks have in place and what it takes to secure a campsite inside the parks. He then shares his best tips for getting the most out of a national park experience in general, as well as when you’re visiting some of the country’s most iconic destinations, including Yosemite, Yellowstone, and the Grand Canyon. At the end of our conversation, Jeremy shares the national parks he thinks are underrated, and if you want to avoid the crowds of the national parks, he also shares his picks for the country’s best state parks.

Resources Related to the Podcast* Jeremy’s previous appearance on the AoM podcast: Episode #711: — How to Plan the Ultimate Road Trip * recreation.gov * nps.gov * KOA campgrounds * AoM Article: Beat the Crowds (And the Fees) With Dispersed Camping

Connect With Jeremy Puglisi* The RV Atlas website * The RV Atlas podcast * RV Atlas on Instagram * RV Atlas on Twitter

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Inside Medicine with Private Medical ✓Claim

Key Takeaways * GLP-1 agonists target factors in the brain and gut that drive obesity in the first place * GLP-1 agonists highlight that obesity isn’t just about behavioral change and individual responsibility, but there are biological mechanisms contributing to obesity * Users tend to follow a significantly reduced meal schedule but it’s important to keep protein intake high and incorporate resistance training 2-3x per week (at least 30-minute sessions) * The best results will still come from users who use GLP-1 agonists in combination with lifestyle modifications – this will also help with plateaus that will happen * Tips to push through a plateau: exercise, self-monitoring behaviors (food tracking, weight monitoring), celebrate non-scale victories (increased energy, increased activity, etc.)

Read the full notes @ podcastnotes.org

Private Medical physicians Dr. Natalie Walsh and Dr. Tatiana Ivan. Dr. Michelle Cardel, an obesity and nutrition scientist, registered dietitian, and the Head of Clinical Research & Nutrition at WeightWatchers. In this interview, she uncovers misconceptions about weight loss, including the truth about GLP-1 inhibitors, most commonly known under brand names like Ozempic and Wegovy. She also discusses the science of lifestyle change, how to talk about weight and health with our children, and the challenges of weight maintenance.
We hope this episode inspires you to think differently about your health and the healthcare system. Please subscribe to our feed and our bimonthly medical dispatch.

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Art of Manliness

Key Takeaways * Low testosterone is often best treated if 1) you have symptoms and 2) have a testosterone level below 400 * Testosterone levels can vary depending on the quality of your recent sleep and diet * Symptoms of low testosterone: depression, anxiety, low libido, erectile dysfunction, low sperm production * People who are significantly hypogonadal for a long time are at a much higher risk for osteoporosis, neurodegenerative disease, cardiovascular disease, and others * Metabolic syndrome is the most common cause of low testosterone * Obstructive sleep apnea is the second most common cause of low T * For most men, an optimal testosterone number is between 500 and as high as you can go naturally * How to improve T: get better and more sleep, improve your diet, manage stress, drink less alcohol, etc. + Improving these behaviors will make you more insulin sensitive (which is a good thing) * Testosterone replacement therapy (TRT) is an option when the benefits of increasing T outweigh the risks of remaining at low levels of T, and when the patient understands the risks and the benefits of the therapy * Supplements mentioned by Dr. Kelly Gillett for testosterone optimization:Creatine,L-Carnitine, Calcium D-Glucarate, andTongkat Ali

Read the full notes @ podcastnotes.org

When men think about optimizing their hormones, they tend only to think about raising their testosterone. But while increasing T can be important, an ideal health profile also means having testosterone that's in balance with your other hormones as well.

Today on the show, Dr. Kyle Gillett joins me to discuss both of those prongs of all-around hormone optimization. We start with a quick overview of the different hormones that affect male health. We then get into what qualifies as low testosterone and how to accurately test yours. We also discuss what causes low testosterone in individual men, and how its decline in the general male population may be linked to both birth control and the world wars. In the second half of our conversation, we discuss how to both raise testosterone and get rid of excess estrogen, including the use of some effective supplements you may never have heard of. We then get into the risks and benefits of taking TRT, before ending our discussion with what young men can do to prepare for a lifetime of optimal T and hormonal health.

Resources Related to the Podcast* AoM series on testosterone, including How I Doubled My Testosterone Levels Naturally * AoM Podcast #761: How Testosterone Makes Men, Men * AoM Podcast #878: The Fitness Supplements That Actually Work

Connect With Dr. Kyle Gillett* Kyle on IG * Gillett Health Podcast on Spotify and Apple * Gillett Health on YouTube * Gillett Health website

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Business Breakdowns✓Claim

Key Takeaways * Check Out the Business Breakdowns Episode Page & Show Notes

Read the full notes @ podcastnotes.org

This is Dom Cooke and today we’re breaking down Bayern Munich. Bayern is Germany’s most successful football club and one of the world’s biggest. Most importantly, it makes a great case for being the best-run club in football. It has an enterprise value close to €3 billion, no debt, has been profitable for 3 decades, and is majority owned by fans. Plus, it has a trophy cabinet to rival any club worldwide. Bayern has won a record 32 national Bundesliga titles, including the last ten in a row, and has won the prestigious Champions League, six times.
To break down the business behind the club, I’m joined by Marie Schulte-Bockum, a football journalist and Munich resident. Please enjoy this Business Breakdown of FC Bayern Munich.
For the full show notes, transcript, and links to the best content to learn more, check out the episode page here.

This episode is brought to you by Tegus. Tegus is the modern research platform for leading investors, and provider of Canalyst. Tired of calculating fully-diluted shares outstanding? Access every publicly-reported datapoint and industry-specific KPI through their database of over 4,000 driveable global models handbuilt by a team of sector-focused analysts, 25+ industry comp sheets, and Excel add-ins that let you use their industry-leading data in your own spreadsheets. Tegus’ models automatically update each quarter, including hard to calculate KPIs like stock-based compensation and organic growth rates, empowering investors to bypass the friction of sourcing, building and updating models. Make efficiency your competitive advantage and take back your time today. As a listener, you can trial Canalyst by Tegus for free by visiting tegus.co/patrick.

Business Breakdowns is a property of Colossus, LLC. For more episodes of Business Breakdowns, visit joincolossus.com/episodes.

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Show Notes
(00:02:38) - (First question) - Overview of Bayern Munich
(00:05:37) - How Bayern’s been able to maintain such consistent success writ large
(00:12:39) - What the 50+1 rule is and its implications for German football clubs
(00:17:24) - Major differences between the Bundesliga and other European leagues
(00:22:30) - What it takes to run a high performance team like Bayern Munich
(00:28:39) - Driving profits and the three major revenue buckets for Bayern Munich
(00:35:48) - Germany’s influence being the biggest economy in the European Union
(00:38:40) - How important European football is to every major club and broadcasting revenue
(00:43:20) - Whether Bayern are buyers, builders, or borrowers in regards to their team
(00:51:15) - Overview of their expenses and the size of their wage bill
(00:53:43) - What financial fair play is and how it protects football clubs
(00:57:27) - How they’ve managed to cultivate one of the biggest fanbases in the world
(01:02:14) - Potential risks for Bayern Munich’s continued success
(01:04:18) - League-level discussions around sharing revenue equitably
(01:05:34) - Lessons for builders and investors when studying Bayern Munich’s story
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Huberman Lab

Key Takeaways * Psilocybin’s main effect is to mimic serotonin in a very specific way, leading to neuroplasticity * The goal of psilocybin is the adaptive rewiring of the brain, not just rewiring of the brain – you want to rewire that leads to new and interesting ideas * Clinical trials using psilocybin for the treatment of depression are outperforming standard therapy and SSRIs (and other antidepressants) + A combination of psilocybin + talk therapy shows evidence of the strongest long-lasting results * Psilocybin increases communication across the brain and reduces the hierarchical organization of the brain, broadening the flow of information (including interoception and exteroception) * “During the psilocybin journey, people have the opportunity to learn new relationships between different sensory and emotional states. Those new relationships seem to persist long after the psychedelic journey is finished.” – Dr. Andrew Huberman * Best practices for an effective guided psilocybin journey: + Sit or lie down comfortably with eyes closed or an eye mask + Music is critical to the experience + 1 or more people present should not be on psilocybin + No food at least 4 hours prior to the journey * Key features of the trip from those who experience positive results: a sense of unity, sense of spirituality, sense of bliss at some point during the experience, insight, and learning about one’s life * Current clinical studies and areas of promise for psilocybin use: treatment resistance depression, cancer-related depression, and anxiety + Newer studies are exploring use for alcohol abuse, tobacco addiction, OCD, and more

Read the full notes @ podcastnotes.org

In this episode, I discuss what psilocybin is (chemically) and how it works at the cellular and neural circuit level to trigger neuroplasticity, which is our brain’s ability to rewire itself in ways that lead to long-lasting shifts in our emotional, cognitive and behavioral patterns and abilities. I discuss the emerging clinical trial evidence for the use of psilocybin in the treatment of depression, addictions and other psychiatric challenges. I explain the typical duration and phases of a psilocybin journey, the different categories of dosages often used and I explain the importance of set, setting and support when using psychedelics. I explain which groups of people place themselves at great risk by taking psilocybin as well as groups that could benefit, and I highlight the rapidly changing legal and medical landscape around psilocybin. This episode is a thorough exploration of psilocybin from the scientific and clinical literature perspective and ought to be of interest to anyone curious about psilocybin, mental health, neuroplasticity and/or psychedelics more generally.
For the full show notes, visit hubermanlab.com.
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Timestamps
(00:00:00) Psilocybin, Legal Considerations
(00:08:32) Sponsors: Eight Sleep, ROKA, HVMN
(00:12:00) Psilocybin Becomes Psilocin in the Gut, Serotonin
(00:17:00) The Serotonin 2A Receptor, Therapeutic Outcomes SSRIs vs. Psilocybin
(00:21:40) Serotonin Receptor Expression; Visual Hallucinations & Eyes Closed
(00:27:21) Safety & Cautions for Specific Patient Populations
(00:29:13) Sponsor: AG1 (Athletic Greens)
(00:30:28) Psilocybin, “Magic Mushrooms” Dosing, Micro-Dosing, “Heroic Doses”
(00:36:21) Psychedelic Journey: Set, Setting & Support
(00:43:43) Music & the Psilocybin Journey; Duration of Effects
(00:48:58) Psilocybin & the Brain: Subjective Experiences, Perception
(00:58:36) Sponsor: LMNT
(00:59:48) Brain Networks & Therapeutic Outcomes
(01:05:23) Creativity; Music, Emotionality & Psychedelic Journeys
(01:12:39) Depression & Psychedelics as Neuroplasticity “Wedge”
(01:16:53) Positive Psychedelic Journeys, Unity, “Oceanic Boundlessness”
(01:25:23) “Bad Trips”, Anxiety & Physiological Sighs
(01:32:57) Therapeutic Use of Psilocybin
(01:36:11) Neuroplasticity, Structural Brain Changes & Psilocybin
(01:48:08) Psychedelics: Therapeutic Breakthroughs & Depression
(01:56:37) Combining Psilocybin Therapy & Talk Therapy, Antidepressant Effects
(02:03:11) Psilocybin Experience & Mental Health
(2:06:42) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media
Title Card Photo Credit: Mike Blabac
Disclaimer

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The Great Simplification with Nate Hagens✓Claim

Key Takeaways * Check Out the Great Simplification Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

In this episode, Dr. Robert Lustig joins Nate to dive into the metabolism of the micro level of human systems - the humans ourselves. Over the last century, accompanying the transformation of our energy systems, our food and consumption patterns have been massively transformed. One of the biggest areas of change is the dramatic increase in sugar consumption. But are our bodies adapted to eating such high sugar, processed foods? What are the health effects connected to this way of eating? And, writ large, how does our metabolic dysfunction as individuals contribute to the energy hungry global Superorganism? What are the systemic drivers that currently prevent a shift towards healthier food systems? Can changing how we eat make us healthier - and thus better equipped to face the complex challenges of the metacrisis?

About Robert Lustig:

Robert H. Lustig, M.D., M.S.L. is Emeritus Professor of Pediatrics in the Division of Endocrinology, and Member of the Institute for Health Policy Studies at UCSF. Dr. Lustig is a neuroendocrinologist, with expertise in metabolism, obesity, and nutrition. He is one of the leaders of the current “anti-sugar” movement that is changing the food industry. He has dedicated his retirement from clinical medicine to help to fix the food supply any way he can, to reduce human suffering and to salvage the environment. Dr. Lustig graduated from MIT in 1976, and received his M.D. from Cornell University Medical College in 1980. He also received his Masters of Studies in Law (MSL) degree at University of California, Hastings College of the Law in 2013. He is the author of the popular books Fat Chance (2012), The Hacking of the American Mind (2017), and Metabolical: The Lure and the Lies of Processed Food, Nutrition, and Modern Medicine (2021).

For Show Notes and More visit: https://www.thegreatsimplification.com/episode/69-robert-lustig

To watch this video episode on Youtube → https://youtu.be/onVqjZOYlQs

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Founders✓Claim

Key Takeaways * Check Out the Founders Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

What I learned from reading The Mind of Napoleon: A Selection of His Written and Spoken Words edited by J. Christopher Herold.

This episode is brought to you by EightSleep: Get the best sleep of your life and unlock more energy with the Pod 3. Go to eightsleep.com/founders/

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[3:45] A man who combined energy of thought and energy of action to an exceptional degree.

[4:45] He knows that men have always been the same, that nothing can change their nature. It is from the past that he will draw his lessons in order to shape the present.

[5:15] Destiny must be fulfilled. That is my chief doctrine.

[6:05] Napoleon: A Concise Biography by David Bell (Founders #294)

[9:25] To aim at world empire seemed to Napoleon a most natural thing.

[10:00] To have lived without glory, without leaving a trace of one's existence, is not to have lived at all.

[10:55] The greatest improvisation of the human mind is that which gives existence to the nonexistent.

[11:45] The best way to understand a person is to listen to that person directly. — Make Something Wonderful: Steve Jobs in his own words (Founders #299)

[12:55] The great majority of men attend to what is necessary only when they feel a need for it—the precise time when it is too late.

[16:10] The worst way to live according to Napoleon:

When on rising from sleep a man does not know what to do with himself and drags his tedious existence from place to place; when, scanning his future, he sees nothing but dreadful monotony, one day resembling the next; when he asks himself, "Why do I exist?”—then, in my opinion, he is the most wretched of all.

[17:45] Instead his (Steve Jobs) ego needs and personal drives led him to seek fulfillment by creating a legacy that would awe people. A dual legacy, actually: building innovative products and building a lasting company. He wanted to be in the pantheon with, indeed a notch above, people like Edwin Land, Bill Hewlett, and David Packard. — Steve Jobs: The Exclusive Biography by Walter Isaacson. (Founders #214)

[19:15] He must know himself. Until then, all endeavors are in vain, all schemes collapse.

[20:15] Napoleon on George Washington: Britain refused to acknowledge either him or the independence of his country; but his success obliged them to change their minds and acknowledge both. It is success which makes the great man.

[21:15] Washington saw the conflict as a struggle for power in which the colonists, if victorious, destroyed British pretentions of superiority and won control over half of a continent. — Franklin & Washington: The Founding Partnershipby Edward Larson. (Founders #251)

[23:15] If you do everything you will win: All great events hang by a single thread. The clever man takes advantage of everything, neglects nothing that may give him some added opportunity; the less clever man, by neglecting one thing, sometimes misses everything.

[23:45] Warren Buffett: We are individually opportunity driven. — All I Want To Know Is Where I'm Going To Die So I'll Never Go There: Buffett & Munger – A Study in Simplicity and Uncommon, Common Sense by Peter Bevelin. (Founders #286)

[24:15] Imagination rules the world.

[25:00] Ambition is a violent and unthinking fever that ceases only when life ceases.

[34:52] The corpse of an enemy always smells sweet.

[35:30] Roots of Strategy: Book 1

[38:45] Robert Caro profiled two men who seeds were not high (in a tournament) they were without many advantages. And to get all the way to the top you probably had to sacrifice everything to the effort. The meta lesson is if you are not willing to pay that price presume someone else will.

If you want something like the presidency (or being a billionaire) you should presume there is someone out there who will devote all their time, money, relationships, sense of ethics, everything in sacrifice of that one goal. Of course that person would win that race. — Invest Like The Best Sam Hinkie Find Your People

[40:45] I do not want be roadkill on the modern-day Napoleon's path to glory.

[43:15] The ancients had a great advantage over us in that their armies were not trailed by a second army of pen pushers.

[44:05] A wasted life should be your greatest fear.

[46:30] Make use of every possible opportunity of increasing your chances of victory.

[48:55] Paul Graham on Be Hard to Kill:

The way to make a startup recession-proof is to do exactly what you should do anyway: run it as cheaply as possible.

For years I've been telling founders that the surest route to success is to be the cockroaches of the corporate world. The immediate cause of death in a startup is always running out of money. So the cheaper your company is to operate, the harder it is to kill. — Paul Graham’s essays (Founders #275)

[51:30] Winning is the main thing. Keep the main thing, the main thing.

Subscribe to listen to Founders Premium — Subscribers can ask me questions directly and listen to Ask Me Anything (AMA) episodes.

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“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

All I Want To Know Is Where I'm Going To Die So I'll Never Go There: Buffett & Munger – A Study in Simplicity and Uncommon, Common Sense

Franklin & Washington: The Founding Partnership

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Stuff You Should Know✓Claim

Key Takeaways * While every manhunt is unique, there are some principles that hold true for all manhunts * Law enforcement typically gets the public involved as soon as possible * Generally, authorities will establish a containment zone, then conduct a door-to-door search, then shut down public forms of transportation, schools, businesses, etc. * The man who killed Martin Luther King Jr. was an escapee from a Missouri prison; following the assassination, he made his way to Canada using a forged passport, then to Portugal, and eventually to the UK where he was finally apprehended * Ted Kaczynski, the Unabomber, was on the run for 18 years before his brother identified his writing style in his manifesto and alerted the authorities * Whitey Bulger was on the run for 16 years before a woman working at a hair salon recognized his girlfriend from an FBI-sponsored commercial and tipped off the police * There are many loopholes that law enforcement can use during manhunts * Crowd-sourced manhunts are becoming increasingly popular given the rise of social media and the online types obsessed with true crime

Read the full notes @ podcastnotes.org

When a suspect or prisoner goes on the lam there are plenty of ways to hide: in plain sight, in the mountains, in another country. There are as many types of ways law enforcement uses to track wanted people as their are ways to go on the lam, but there are some founding principles to carrying out a successful manhunt and they actually include you. Learn about how the fuzz tracks down fugitives and how it's evolving in the age of social media in this classic episode.

See omnystudio.com/listener for privacy information.

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Founders✓Claim

Key Takeaways * You do not get to the top of your profession without studying the greats that came before you * Tiger hit his first golf ball when he was 11 months old, and by the age of two he would spend several hours each day hitting golf balls * Tiger was unusually disciplined as a five-year-old, was a gifted student, and seldom spoke * Earl Woods had a “messiah-like” vision for his son * At the age of 12, Earl Woods put his son through what he called “Woods Finishing School,” which included psychological warfare and prisoner-of-war techniques that he once taught to soldiers in Vietnam * “Practice, practice, practice” was how Tiger got so good at golf * It is hard to compete against someone who is obsessed and willing to do more work than anyone else * “I want to be the Michael Jordan of golf. I want to be the best ever.” – Tiger Woods * Tiger never rested after a win; the joy he felt from winning tournaments was always fleeting * Woods kept score; trophies symbolized wins, and wins denoted dominance * Tiger was obsessed with privacy and loyalty; he owned two private yachts, one named “Privacy” and another “Solitude” * The breakdown of Tiger’s body was accelerated by his extreme exercise regime and his fascination with Navy SEAL training * Tiger’s greatest strength – his high tolerance for pain – may have also been his greatest weakness * “The problem isn’t getting rich. It is staying sane.” – Charlie Munger

Read the full notes @ podcastnotes.org

What I learned from reading Tiger Woods by Jeff Benedict and Armen Keteyian.

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This episode is brought to you by Meter: Meter is the easiest way for your business to get fast, secure, and reliable internet and WiFi in any commercial space. Go to meter.com/founders

Follow one of my favorite podcasts Invest Like The Best and listen to episode 326 Alexis Rivas

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[3:00] He was someone no one had ever seen or will ever see again.

[5:20] You can always understand the son by the story of his father. The story of the father is embedded in the son. — Francis Ford Coppola: A Filmmaker's Life by Michael Schumacher. (Founders #242)

[7:15] His output was enormous, much greater than that of nine tenths of other composers. He was a mature artist in most forms at the age of twelve. There was never a month, often scarcely a week, when he did not produce a substantial score. — Mozart: A Life by Paul Johnson. (Founders #240)

[7:50] Tiger's opponents were never people; it was always history.

[14:05] I've always been a practice player. I believe in it. — Michael Jordan: The Lifeby Roland Lazenby. (Founders #212)

[17:00] Grinding It Out: The Making of McDonald's by Ray Kroc. (Founders #293)

[18:30] Tiger was filling his mind with words that were intended to make him great. He wrote some of the messages from the self-help cassettes on a sheet of paper that he taped to his bedroom wall:

I believe in me

I will own my own destiny

I smile at obstacles

I am first in my resolve

I fulfill my resolutions powerfully

My strength is great

I stick to it, easily, naturally

My will moves mountains

I focus and give it my all

My decisions are strong

I do it with all my heart

Tiger listened to those tapes so often that he wore them out.

[31:50] People would ask him how did you get so good Tiger? And he would answer, practice, practice, practice.

[32:10] The world is a very malleable place. If you know what you want, and you go for it with maximum energy and drive and passion, the world will often reconfigure itself around you much more quickly and easily than you would think. —The Pmarca Blog Archive Ebook by Marc Andreessen.

[36:45] The Score Takes Care of Itself: My Philosophy of Leadership by Bill Walsh. (Founders #106)

[40:15] That’s all training is. Stress. Recover. Improve. You’d think any damn fool could do it. But you don’t. You work too hard and rest too little and get hurt. — Bowerman and the Men of Oregon: The Story of Oregon's Legendary Coach and Nike's Cofounder by Kenny Moore. (Founders #153)

[46:15] Money didn't motivate him. Nor did fame. He played for the hardware. He played for the win.

[53:45] Robert Caro’s Books

Subscribe to listen to Founders Premium — Subscribers can ask me questions directly and listen to Ask Me Anything (AMA) episodes.

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“I have listened to every episode released and look forward to every episode that comes out. The only criticism I would have is that after each podcast I usually want to buy the book because I am interested so my poor wallet suffers. ” — Gareth

Be like Gareth. Buy a book: All the books featured on Founders Podcast

The Score Takes Care of Itself: My Philosophy of Leadership

Francis Ford Coppola: A Filmmaker's Life

Grinding It Out: The Making of McDonald's 1st edition by Ray Kroc (1977) Hardcover

Bowerman and the Men of Oregon: The Story of Oregon's Legendary Coach and Nike's Cofounder

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Tetragrammaton with Rick Rubin✓Claim

In this episode, Rick speaks with Phil Jackson. Phil Jackson is the head coach with the most NBA titles. His holistic approach to coaching, influenced by Eastern philosophy, led to his nickname, "The Zen Master,” and later to his induction into the Basketball Hall of Fame.

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All-In with Chamath, Jason, Sacks & Friedberg

Podcast Notes Foreign Policy: Ukraine / Russia * Robert F. Kennedy Jr. initially supported humanitarian aid to Ukraine, but became suspicious of the mission’s intent. * Believes that the US decision-making has been about maximizing the violence of the war and rejecting opportunities to settle the conflict. * RFK Jr. believes the Neocons in the White House want regime change in Russia and aim to exhaust and degrade Russian forces. + “And President Biden acknowledged that one of his objectives in the war is regime change in Russia, removing Vladimir Putin.” – Robert F. Kennedy Jr. * Over 300,000 Ukrainian deaths in the most violent conflict since World War II * 2014 U.S. involvement in Ukraine disagreement led to the overthrow of the democratically elected government, prompting Russia’s invasion of Crimea * Discusses the Minsk Accords (2014) plan for making Donbas an autonomous region within Ukraine and preventing Ukraine’s entry into NATO * As President, Robert F. Kennedy Jr. would aim to negotiate a ceasefire and settle the war * Discusses his uncle, John F. Kennedy’s approach to foreign policy and war + “The principal job of a president of the United States is to keep the nation out of war.” – John F. Kennedy + “We’re all on an arc. And we need to understand each other’s motives and not just vilify each other.” – John F. Kennedy

Read the full notes @ podcastnotes.org

(0:00) Bestie intros!

(0:49) Jason and Sacks intro Robert F. Kennedy Jr.

(3:46) Foreign policy: Ukraine / Russia

(17:17) Foreign policy: Taiwan / China

(18:57) Government spending: Fiscal responsibility, where to cut budget, debt ceiling

(33:22) US Govt Intelligence Agencies: "Deep State," increasing accountability, "agency capture"

(46:04) COVID: mishandling, more "agency capture," vaccine policy

(55:10) Broader thoughts on vaccines in general

(1:05:54) Energy policy: thoughts on nuclear

(1:15:29) Culture wars: trans issues, CRT in schools, public vs charter schools

(1:23:09) Media: declining trust, misaligned incentives, conflict of interest with large advertisers

(1:30:07) Mainstream media coverage, ABC News debacle, evolving with new information, money in politics

(1:40:37) The Besties do a post-interview debrief

(1:57:30) Announcing All-In Summit 2023!

Follow the besties:

https://twitter.com/chamath

https://linktr.ee/calacanis

https://twitter.com/DavidSacks

https://twitter.com/friedberg

Follow Robert F. Kennedy Jr:

https://twitter.com/RobertKennedyJr

Follow the pod:

https://twitter.com/theallinpod

https://linktr.ee/allinpodcast

Intro Music Credit:

https://rb.gy/tppkzl

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Intro Video Credit:

https://twitter.com/TheZachEffect

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Huberman Lab

Key Takeaways * The human sense of smell is innately extremely sensitive and can be trained to be even more sensitive, especially in the absence of other senses (like vision or hearing) * Every time you meet someone you are taking chemicals from that person and applying it to your own body to process information about that person – this may explain why some people become “fast friends” or click right away * If you lose your sense of smell for 1-1.5 years, it’s unlikely you’ll ever get it back; it’s a ‘use it or lose it’ system * Loss of smell is an early indicator of neurological degeneration and disease * We’re constantly shifting our nasal cycle AKA which nostril we use most through a mechanism driven by the sympathetic/parasympathetic nervous system * Information processing & cognition is linked to our olfactory system * We are always sensing our own odor clouds to change our cognition and behavior – whether you realize it or not * In our most basic behaviors, we follow our nose not our eyes: if a food is visually appealing but smells bad, we are less likely to eat it; we’ll be more attracted to a romantic partner who smells pleasant regardless of looks versus a potential partner who looks nice but smells bad * The future of digitized olfaction may be used in medical diagnoses (but nowhere in the near future)

Read the full notes @ podcastnotes.org

In this episode, my guest is Noam Sobel, PhD, professor of neurobiology in the department of brain sciences at the Weizmann Institute of Science. Dr. Sobel explains his lab’s research on the biological mechanisms of smell (“olfaction”) and how sensing odorants and chemicals in our environment impacts human behavior, cognition, social connections, and hormones. He explains how smell is a crucial component of “social sensing” and how we use olfaction when meeting new people to determine things about their physiology and psychology, and he explains how this impacts friendships and romantic partners. He explains how smell influences emotions, hormone levels, memories and the relationship between breathing and autonomic homeostasis. He describes how smell-based screening tests can aid disease diagnosis and explains his lab’s work on digitization of smell — which may soon allow online communication to include “sending of odors” via the internet. Dr. Sobel’s work illustrates how sensitive human olfaction is and how it drives much of our biology and behavior.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
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Thesis: https://takethesis.com/huberman
Helix Sleep: https://helixsleep.com/huberman
InsideTracker: https://insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Noam Sobel
(00:03:46) Sponsors: ROKA, Thesis, Helix Sleep
(00:06:46) Olfaction Circuits (Smell)
(00:14:49) Loss & Regeneration of Smell, Illness
(00:21:39) Brain Processing of Smell
(00:24:40) Smell & Memories
(00:27:52) Sponsor: AG1 (Athletic Greens)
(00:29:07) Humans & Odor Tracking
(00:39:25) The Alternating Nasal Cycle & Autonomic Nervous System
(00:48:18) Cognitive Processing & Breathing
(00:54:47) Neurodegenerative Diseases & Olfaction
(01:00:12) Congenital Anosmia
(01:05:01) Sponsor: InsideTracker
(01:06:19) Handshaking, Sharing Chemicals & Social Sensing
(01:15:07) Smelling Ourselves & Smelling Others
(01:22:02) Odors & Romantic Attraction
(01:24:58) Vomeronasal Organ, “Bruce Effect” & Miscarriage
(01:40:20) Social Chemo-Signals, Fear
(01:50:26) Chemo-Signaling, Aggression & Offspring
(02:03:57) Menstrual Cycle Synchronization
(02:12:11) Sweat, Tears, Emotions & Testosterone
(02:27:46) Science Politics
(02:37:54) Food Odors & Nutritional Value
(02:45:34) Human Perception & Odorant Similarity
(02:52:12) Digitizing Smell, COVID-19 & Smell
(03:05:50) Medical Diagnostic Future & Olfaction Digitization
(03:10:55) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Huberman Lab

Introduction * View things close up (a few inches to 2 feet away) and far away (4-8 feet away) throughout the day – we spend a lot of time only looking at things close up (i.e., on our phones) + Near-sightedness is increasing at record rates as a result * The length of the eyeball and movement of the lens is influenced by how close or far we view things, especially during the development + If you only look at things close up, the image lands too close to the lens and leads to nearsightedness * Studies have shown kids develop myopia if they look at screens too much during development * Tip #1: spend time daily visually scanning at a distance, or walking and not looking at anything in particular – the general rule of thumb: for every hour you spend looking at things 3 ft away or less, get at least an hour per day looking at things further away * Tip #2: time outside per day in sunlight (ideally 2 hours per day) leads to a lower incidence of myopia, particularly in children + Time in sunlight doesn’t have to be free of screens or work, just time in sunlight or opening a window to get natural light exposure * Tip #3: check out the smooth pursuit visual tasks or near-far vision exercises to offset or reverse vision loss * Nutrition and supplements for eye health: get enough vitamin A in the purest food form (found in leafy greens, liver, etc.), lutein from food sources (such as eggs) may help protect against age-related macular degeneration * There are people who swear by reducing reliance on corrective lenses and working on eye health exercises to improve vision * Red light research: exposure to red light (650-720 nm range) early in the day (1-3 minutes) can offset some age-related vision decline

Read the full notes @ podcastnotes.org

Welcome to a preview of the sixth Ask Me Anything (AMA) episode, part of the Huberman Lab Premium subscription.
The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.
Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium
Timestamps
(00:00:00) Introduction
(00:01:53) What Are the Best Eye Exercises, Supplements, Food, Protection Practices for the Eye?
(00:33:55) Huberman Lab Premium

In the full AMA episode, we discuss:

Why We Yawn and Don't Yawn During Sleep

How to Stay Motivated and Overcome Lethargy in Learning

Title Card Photo Credit: Mike Blabac
Disclaimer

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Deep Questions with Cal Newport✓Claim

Key Takeaways * Check Out the Deep Questions Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Are smartphones bad for kids? Cal walks through the data on this question, including how researchers came to be worried, their findings, critiques of their findings, and where we are today. He then gives recommendations for how to think about technology when it comes to your kids.

Below are the questions covered in today's episode (with their timestamps). Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo

Video from today’s episode: youtube.com/calnewportmedia

Today’s Deep Question: Are smartphones bad for kids? [3:10]

Is the deep life dull? [49:35]
How do I stop doom-scrolling when I’m tired? [53:49]
Are smartphones bad for older people? [57:35]
How does Cal decide to adopt new technology or software? [1:02:06]
How do I stay deep while traveling at conferences? [1:06:33]

The Books Cal read in March 2023 [1:12:38]

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Thanks to Jesse Miller for production, Jay Kerstens for the intro music, and Mark Miles for mastering.

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Huberman Lab

Key Takeaways * Mental training and visualization is best used to enhance speed and accuracy of a skill you already have some proficiency at, not necessarily for learning new things * “Mental training and visualization cannot replace execution of real world cognitive or motor tasks you want to learn…but is effective in enhancing the speed at which you learn and the stability of that learning over time.” – Dr. Andrew Huberman * Principles of mental visualization: + (1) mental visualization needs to be brief (15-20 sec) and repeated; + (2) mental visualization needs to be combined with real world experience; + (3) mental training needs to be similar to real world experience; + (4) naming and giving identity to real world skill and applying the same name to visualization enhances learning; + (5) it takes longer to perform complex motor sequences in mental training and visualization just like it would in the real world * Choosing between real world training and mental training: real world training is better than mental training; mental training is better than no training; but ideally – you’ll use mental training to augment real world training and improve speed, accuracy, and consistency * Mental training can also be used to get you to stop or ‘no go’ components of motor learning, like restricting inappropriate movements or thoughts (e.g., withholding inappropriate action or action sequence) + For this training, it’s especially important to perform mental training and real world training in combination

Read the full notes @ podcastnotes.org

In this episode, I explore the science of mental visualization and its application for learning motor and cognitive skills. I discuss neuroplasticity-based skill development and the roles of focus, sleep, movement restriction, and agitation. I then present five key principles of mental visualization to enhance learning speed, accuracy, and consistency. I also provide examples of specific protocols, including repetitions, rest periods, and session frequency, and how to adapt these methods for injuries or breaks from traditional training. Throughout, I reference the scientific studies supporting these concepts. This episode should allow anyone to learn or teach more effectively through the use of mental visualization and training.
For the full show notes, visit hubermanlab.com.
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Timestamps
(00:00:00) Mental Training & Visualization
(00:04:46) Sponsors: LMNT, Maui Nui, Eight Sleep
(00:08:04) Developmental vs. Adult Neuroplasticity
(00:11:42) Learning New Skills: Focus & Sleep
(00:14:49) Long-Term Potentiation (LTP), Long-Term Depression (LTD) & New Skills
(00:23:42) Principle #1: Very Brief, Simple, Repeated Visualization
(00:29:36) Sponsor: AG1 (Athletic Greens)
(00:30:51) Principle #2: Mental Training Cannot Replace Real Training
(00:37:36) Principle #3: Combining Real & Mental Training
(00:43:17) Principle #4: Assigning Real-World Labels to Visualizations
(00:50:37) Principle #5: Mental Imagery Equivalence to Real-World Perception
(00:55:28) Tools: Effective Mental Training: Epochs, Repetitions, Sets & Frequency
(01:03:43) Sponsor: InsideTracker
(01:05:00) Adding Mental Training; Injury, Travel or Layoffs
(01:11:09) Timing of Mental Training & Sleep
(01:15:17) Role of Gender & Age on Mental Training
(01:17:10) First-Person vs. Third-Person Visualization; Eyes Open vs. Closed
(01:23:53) Physical Skills, Motor Cortex & Cerebellum
(01:31:15) “Go” & “No-Go” Pathways
(01:34:19) Stop-Signal Task, Withholding Action
(01:44:19) Aphantasia, Synesthesia; Social Cognition
(01:52:58) Mental Training Practice & Benefits
(01:57:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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My First Million

Key Takeaways * People feel uncomfortable attending money-related events because it makes them feel bad about themselves. * Do not to try to pick individual stocks but rather invest in a target date fund or index fund. “You’re never going to pick the next Amazon. That was complete luck.” * Ramit spends hundreds of thousands of dollars per year on convenience and believes in having an unlimited budget for the things that matter most. * People tend to accumulate a lot of stuff, often with excessive attachment to items. It’s crucial to be conscious of what we purchase, as these items can become part of our identity and challenging to get rid of. * Ramit believes in having a do not sell (DNS) list for people who don’t fit your ideal customer profile. If someone has credit card debt, Ramit won’t allow them to join his flagship programs. * The books Ramit and Sam are reading include Joseph Kennedy biography, Unreasonable Hospitality, Customers for Life, The Power of the Past, and Color of Law.

Read the full notes @ podcastnotes.org

Episode 446: Sam Parr (@TheSamParr) talks with Ramit Sethi (@ramit) about his new Netflix show, "How To Get Rich" and the "I Will Teach You To Get Rich" podcast, learning to spend money on what you love, how to stand out, and what books he's reading.

Click here to sign up for our event in Austin, TX on Saturday April 29th: mfmpod.com/atx
Want to see more MFM? Subscribe to the MFM YouTube channel here.

Check Out Sam's Stuff:
Hampton
Ideation Bootcamp
* Copy That

Check Out Shaan's Stuff:
Power Writing Course
Daily Newsletter

Links:
"How To Get Rich" - Netflix
I Will Teach You To Be Rich
Delegate and Done
The Luxury Strategy
Kapferer On Luxury
Unreasonable Hospitality
Customers for Life
Power of the Past
*The Color of Law

* Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.

Show Notes:
(01:15) - Ramit's Netflix Show
(06:40) - How Ramit got good with money
(13:25) - Making money vs managing money vs spending money
(35:15) - What do you love spending money on?
(42:35) - How much do you spend on your life?
(47:30) - What is it like to shoot a Netflix show?
(55:40) - How to stand out?
(01:05:30) - Would you ever sell?
(01:19:25) - What are you reading recently?

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Knowledge Project

Key Takeaways * Be the same person at work as you are at home * Earned success is the key to happiness * Understand that reality hits you at every moment and that there are costs to not embracing it * Understand what it is you are actually betting on when you make an investment * Write about the topics that you actually care about; do not write about what you think someone else will think is interesting * “It’s easier to hold your principles 100 percent of the time than it is to hold them 98 percent of the time.” – Dr. Clayton Christensen * Leaders often spend more time worrying about the 95% of people delivering 10% of the value compared to worrying about the 5% of people that deliver 90% of the value * Your role as a leader might be to find a handful of people that will change the trajectory of a company * “The main thing is keeping the main thing the main thing.” – Jim Barksdale * Good decision-makers do not confuse activity with insight * You can bounce back from any mistake other than a mistake of integrity * “I think all you can really do as a leader of a company is have people believe that the decisions you’re making are always in the best interest of the company.” – Ravi Gupta

Read the full notes @ podcastnotes.org

One of the main jobs Ravi Gupta has as a partner at venture capital giant Sequoia Capital is to help founders see the difference between fantasy and reality. On this episode of The Knowledge Project, Gupta dives deep into a wide range of topics that will help you better understand the realities of success, decision making, why it’s crucial to practice doing things you don’t want to do, the best advice he ever received, and the value of quality over quantity. Gupta has served as a partner at Sequoia Capital since 2019. Prior to joining the world of venture capital he served as the Chief Operating Officer and Chief Financial Officer for Instacart, and he also spent a decade working in private equity with KKR & Co. --

Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

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Infinite Loops

Key Takeaways * Check out Infinite Loops Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Alex Danco returns for his seventh (yes, SEVENTH) appearance on Infinite Loops to discuss, as usual, pretty much everything other than the topics we had prepared in advance.

This week, we discuss: The two types of lawyers, what Alex learned from reading Don Quixote, Elon the Reply Guy, the psychology of Seinfeld, the best Wall Street Movies, and much more.

Important Links:

Twitter: https://twitter.com/Alex_Danco
Website: https://alexdanco.com/
Newsletter: https://danco.substack.com/

Show Notes:

The two kinds of lawyers
Medicine, placebo, Don Quixote & theatre
Heroes, villains & main characters
Elon the Reply Guy
Safe words, scams & narrative collapse
Self-deception is multiplayer
The psychology of Seinfeld
To what extent are great innovations already baked into the systems?
Margin Call: The two schools of thought
The best Wall Street movies
MUCH more!

Books Mentioned:

The Theory And Practice Of Gamesmanship Or The Art Of Winning Games Without Actually Cheating; by Stephen Potter
Don Quixote; by Miguel de Cervantes
The Fifth Science; by Exurb1a
The Status Game: On Human Life and How to Play It; by Will Storr
The Lucifer Principle: A Scientific Expedition into the Forces of History; by Howard K. Bloom
Games People Play: The Psychology of Human Relationships; by Eric Berne
Mendel's Dwarf; by Simon Mawer
The Big Short: Inside the Doomsday Machine; by Michael Lewis
The Bonfire of the Vanities; by Tom Wolfe
The Smartest Guys in the Room: The Amazing Rise and Scandalous Fall of Enron; by Peter Elkind & Bethany McLean

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School of Greatness

Key Takeaways * Check out The School of Greatness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

https://lewishowes.com/mindset - Order a copy of my new book The Greatness Mindset today!

Michael Pollan has been writing books and articles about the places where the human and natural worlds intersect for more than 30 years. He is the author of nine books, seven of which have been New York Times bestsellers.

In 2003, Pollan was appointed the Knight Professor of Journalism and director of the Knight Program in Science and Environmental Journalism at the University of California, Berkeley. In 2017, he was appointed professor of the practice of nonfiction at Harvard and the university's first Lewis K. Chan Lecturer in the Arts.  In 2020, along with Dacher Keltner and others, he cofounded the UC Berkeley Center for the Science of Psychedelics. In 2022, Pollan released his four-part docuseries, How to Change Your Mind, on Netflix, which explores the history and uses of psychedelics, including LSD, psilocybin, MDMA and mescaline. Most recently, Pollan released his class on MasterClass where he teaches intentional eating. In the class, he breaks down decades of research to help members rethink their relationship with food and make choices that benefit their health and the planet.

In this episode you will learn,

Everything you need to know about eating intentionally
How important the communal meal is for our overall health
The science of psychedelics and what it teaches us about consciousness, addiction and mental health
The effect caffeine has on the mind and body
How to align your eating habits with your values

Check out Michael's new MasterClass - Intentional Eating

For more information go to

www.lewishowes.com/1424

How Food Heals or Harms Your Body, Aging & Mental Health: https://link.chtbl.com/1075-pod

Build Your Health to Build Your Wealth: https://link.chtbl.com/916-pod

Use Food to Heal Your Body: https://link.chtbl.com/714-pod

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Huberman Lab

Key Takeaways * Neuralink makes neural implants and delivers with a robotic insertion device that helps place tiny electrodes smaller than a human hair throughout a region of the brain * Neuralink goals: + Present – repair motor movement in people with spinal cord injury or paralysis using an external mouse and computer software to decode motor intentions (not connecting brain and motor movement just yet, for now, the focus is on establishing the agency in the movement of things in the world and eventually the body) + Midterm – humans regaining control over some of the ways the brain goes wrong through addiction, depression, obesity, etc. + Long-term – full expansion of human cognition into AI without limit, unrestricted communication (without phone), banding human minds together * Neuroplasticity decreases with age but technology isn’t necessarily the answer here because it involves altering the entire brain whereas machines are highly specialized and focus * Don’t worry about your Bluetooth headphones! It’s unlikely there’s enough energy to produce any harm * Alcohol use is the most common source of brain damage many of us volunteer for – for every drink you have there is a linear increase in brain atrophy and neuron death

Read the full notes @ podcastnotes.org

In this episode, my guest is Matthew MacDougall, MD, the head neurosurgeon at Neuralink. Dr. MacDougall trained at the University of California, San Diego and Stanford University School of Medicine and is a world expert in brain stimulation, repair and augmentation. He explains Neuralink’s mission and projects to develop and use neural implant technologies and robotics to 1) restore normal movement to paralyzed patients and those with neurodegeneration-based movement disorders (e.g., Parkinson’s, Huntington’s Disease) and to repair malfunctions of deep brain circuitry (e.g., those involved in addiction). He also discusses Neuralink’s efforts to create novel brain-machine interfaces (BMI) that enhance human learning, cognition and communication as a means to accelerate human progress. Dr. MacDougall also explains other uses of bio-integrated machines in daily life; for instance, he implanted himself with a radio chip into his hand that allows him to open specific doors, collect and store data and communicate with machines and other objects in unique ways. Listeners will learn about brain health and function through the lens of neurosurgery, neurotechnology, clinical medicine and Neuralink’s bold and unique mission. Anyone interested in how the brain works and can be made to work better ought to derive value from this discussion.
For the full show notes, visit hubermanlab.com.
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Timestamps
(00:00:00) Dr. Matthew MacDougall
(00:04:05) Sponsors: HVMN, Levels, Thesis
(00:07:38) Brain Function & Injury; Brain Tumor Treatment
(00:13:52) Frontal Lobe Filter; Sleep Deprivation
(00:19:00) Neuroplasticity, Pharmacology & Machines
(00:22:10) Neuralink, Neural Implants & Injury, Robotics & Surgery
(00:31:05) Sponsor: AG1 (Athletic Greens)
(00:32:20) Neocortex vs. Deep Brain
(00:36:45) Decoding Brain Signals
(00:42:08) “Confidence Test” & Electrical Stimulation; RFID Implants
(00:51:33) Bluetooth Headphones & Electromagnetic Fields; Heat
(00:57:43) Brain Augmentation & Paralysis
(01:00:51) Sponsor: InsideTracker
(01:02:09) Brain Implants & Peripheral Devices
(01:12:44) Brain Machine Interface (BMI), Neurofeedback; Video Games
(01:22:13) Improving Animal Experimentation, Pigs
(01:33:18) Skull & Injury, Traumatic Brain Injury (TBI)
(01:39:14) Brain Health, Alcohol
(01:43:34) Neuroplasticity, Brain Lesions & Redundancy
(01:47:32) Car Accidents & Driver Alertness
(01:50:00) Future Possibilities in Brain Augmentation & BMI; Neuralink
(01:58:56) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Aarthi and Sriram's Good Time Show✓Claim

Key Takeaways * By keeping the mechanics of your life as straightforward as possible, you can increase the amount of effort you put into the intellectual, creative side of your life * ChatGPT is adding a word at a time and figuring out the likely way that humans would continue that particular piece of text, based on what they have written in a few billion web pages * “This whole idea of computational language just got much more exciting … because it becomes this medium for communication and collaboration between humans and AIs.” – Stephen Wolfram * In the end, the world will have a civilization of AIs that have an infrastructure that operates in these ways that humans cannot readily understand + Ironically, this is the situation that humans have been in with respect to the natural world the whole of our existence + The natural world does all types of computations that we do not really understand, and yet we coexist with the natural world

Read the full notes @ podcastnotes.org

0:00 Intro1:54 How Stephen Wolfram approaches productivity6:12 Stephen's day-in-life7:45 Stephen's outlook on artificial intelligence13:05 The human brain-artificial intelligence analogy16:40 Wolfram's unique approach to GPT31:00 The Pi computation34:14 Risks of AI45:32 Stephen's X factor51:36 Are things as complex as they seem?1:03:00 Do the simple things rightRenowned physicist, mathematician, and computer scientist Stephen Wolfram joined us on the podcast to discuss AI, physics, and more. We explored the state of artificial intelligence and the challenges and opportunities it presents. Stephen shared his insights into the computational universe and cellular automata and their relationship to physics. 🎙️ The Good Times Show: Aarthi Ramamurthy and Sriram Krishnan host conversations with leading builders, and CEOs and reveal what it takes to make it to the inside.

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The Nick Huber Show ✓ Claim

Podcast Notes Key Takeaways * Capital providers are waiting for interest rates to stabilize prior to coming back into the real estate market * Despite how it may seem on Twitter, it is actually really hard to make money in the real estate business * Class A storage is branded as “nice storage” but it requires renting a truck, moving your stuff with a dollie, putting it on an elevator, etc. * As interest rates rise, the people with the capital can now park it in treasury bills and earn 4-5% “risk-free” instead of allocating to real estate ventures * The risk-free rate is no longer 0% like it was for much of the last several years * Many real estate investors, accountants, and CPAs are not aware of cost segregation * Any real estate that people have bought after September 2017 can still be cost-segregated, or “cost-segged” by filing a Form 3115 * Cost segregation is effectively borrowing money from the IRS and works best when you plan to hold the property for several years * You get a look into someone’s brain when you follow them on Twitter * Sharing what you know on Twitter can pull forward your career trajectory by twenty years * Twitter is a modern-day business tool to build trust and friendships at scale * The ability to simplify complex topics and share that with the world is a superpower

Read the full notes @ podcastnotes.org

Today’s episode is a repost from The Fort podcast by Chris Powers that originally aired on February 16th, 2023. I sit down with Chris and my business partner Mitchell Baldridge to discuss the current real estate market, how Twitter changed our lives, and Mitchell and I’s new business RE Cost Seg.

Chris is a mentor of mine and I highly recommend listening to his podcast, The Fort. https://www.thefortpod.com

If you want to learn more about RE Cost Seg, please click here. https://www.recostseg.com

Thank you and I hope you enjoy the conversation.

FREE PDF - How to analyze a property and know what it's worth: https://sweatystartup.ck.page/79046c9b03

Check my free resources about Real Estate: https://sweatystartup.com/courses/

Check out my free Delegation / Hiring 101 course!
Click here: https://nickhuber.podia.com/delegation-hiring-101

We're hiring! Visit:
https://sweatystartup.com/hiring

Check my free resources about Real Estate: https://sweatystartup.com/courses/

Read the full show notes here: https://sweatystartup.com/series/the-nick-huber-show/

Join my Real Estate community here: https://sweatystartup.com/rec

Special thanks to the sponsors:
• https://junipersquare.com
• https://recostseg.com/

Twitter Growth Mastery Course: https://sweatystartup.com/twitter

Want to hire me as a consultant? Click here: https://sweatystartup.com/storage

Have some questions? Send me an email and I'll feature you in the next episode: nick@sweatystartup.com

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Infinite Loops

Podcast Notes Key Takeaways * Words that used to carry a certain weight are now levied all the time, and this debases their meaning * The Woozle Effect: An article makes a claim without evidence, is then cited by another, which is cited by another (and so on), until the range of citations creates the impression that the claim has evidence when really all articles are citing the same uncorroborated source * The Toxoplasma of Rage: Narratives that do the best in the digital age are narratives that not everybody thinks are true, but those that divide people the most * Golden Hammer: When someone, usually an intellectual who has gained a cultish following for popularizing a concept, becomes so drunk with power he thinks he can apply that concept to everything * The Streisand Effect: A narrative that people are trying to suppress will eventually leak out, and it becomes even more appealing to everyone else because of the very fact that it was suppressed * Our minds are configured not to argue for what is true, but for what we want to believe and what we need to believe in order to be part of the tribe * Purity Spiral: Members of political tribes inevitably begin competing with their fellows to be the most ideologically pure. The constant one-upmanship toward moral superiority causes the whole group to become more extreme gradually. * You cannot censor an avalanche * “Certainty is the death of thought.” – Gurwinder Bhogal

Read the full notes @ podcastnotes.org

Gurwinder Bhogal is a writer and programmer who writes about the myriad ways in which technology and psychology conspire to fool us and how we can withstand the covert assault on our senses.

Gurwinder is known for his epic Twitter ‘Megathreads’ which set out a series of powerful concepts for understanding the world.

He joins the show to discuss our tendency to narrativize information, how to overcome the bandwidth tax, why Wikipedia is the world’s largest source of misinformation, and MUCH more!

Important Links:

Megathread: Feb 7, 2020 (53,000 likes)
Megathread: Feb 11, 2022 (62,000 likes)
Megathread: March 18, 2023 (most recent)
Gurwinder's Substack
Gurwinder's Twitter
The Toxoplasma of Rage

Show Notes:

Megathreads & the Woozle effect
AI, the Encyclopedia Disinformatica, and cultivating a garden of Mithridates
Capturing the nuance between dishonesty and lying
The Toxoplasma of Rage
Overcoming the bandwidth tax
Brandishing the golden hammer; why we can’t comprehend large numbers
Tribalism & intersubjectivity
The purity spiral
Are we facing a lost generation?
We are programmed to like complex explanations
Narrativizing information
“Certainty is the death of thought”
Climbing the thinking ladder
MUCH more!

Books Mentioned:

The Fifth Science; by Exurb1a
Talking to Strangers; by Malcolm Gladwell
Tao Te Ching; by Lao Tzu
What's Our Problem?: A Self-Help Book for Societies; by Tim Urban

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What Got You There with Sean DeLaney

Podcast Notes Key Takeaways * Check Out the What Got You There Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Sean Foley is regarded as one of if not the greatest golf teachers in history. Sean has coached some of the best players in the world including Tiger Woods, Justin Rose, Cameron Champ, Lydia Ko, and Danny Willett. He has been voted as the top golf teacher in the world by players on the PGA Tour.

Sean Foley Performance in Orlando, Florida, offers elite golf training and a world-class experience for players of all ages. Sean’s core teaching philosophy is driven by a passion to help golfers evolve into the best players and people they can be, incorporating biomechanics, leading technology, physiology, performance psychology and philosophy into his instruction.

On this episode Sean dives into the biggest barriers people need to overcome for high performance, how to challenge your beliefs that are holding you back and what he’s learned coaching some of the all time great players in the world.

Click HERE for Episode Notes

https://www.seanfoleygolf.com/

www.whatgotyouthere.com

I've studied hundreds of the world's must successful people and compiled:13 Insights from the World’s Most Successful People - Click Here to get access

https://youunleashedcourse.com/

You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential’!

You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you’re capable of.

You know you’re capable of more and want to bring out that untapped potential inside of you.

We teach you how.

Enroll Today!- Click Here

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Radiolab

Podcast Notes Key Takeaways * Sci-Hub is a library website that provides free access to millions of research papers and books, without regard to copyright * It was created in 2011 by a single person named Alexandra Elbakyan * All of the papers made available on Sci-Hub are copyrighted and owned, so open-sourcing them is technically illegal * The four for-profit publishers that dominate the scientific journal industry are charging the scientific community to read the research that was conducted by the scientific community * At its peak, Sci-Hub hosted over 90% of every scientific article that was ever published * The publishes have sued Alexandra Elbakyan for violating copyright laws, claiming that she broke the law by distributing material that she did not have the legal right to distribute * She did not show up for the trial and became famous for not showing up to subsequent hearings and trials * “Maybe I was a little bit naive. But I thought the app [was] going to overthrow academic publishing and the corporatized system.” – Alexandra Elbakyan * She is involved in an ongoing copyright case in India, which she has chosen to participate in because she believes she has a higher chance of winning + As part of an agreement, new uploads to Sci-Hub have been paused until a verdict is reached (they have now been paused since 2020) * However, the scientific journal industry is changing and shifting more toward the open-access model * By 2026, every paper that gets federal funding will be made immediately free for all to read * Sci-Hub may be losing the battle, but open access is winning the war

Read the full notes @ podcastnotes.org

How much does knowledge cost? While that sounds like an abstract question, the answer is surprisingly specific: $3,096,988,440.00. That’s how much the business of publishing scientific and academic research is worth.

This is the story of one woman’s battle against a global network of academic journals that underlie published scientific research. In 2011, Alexandra Elbakyan had just moved home to Kazakhstan after a disappointing few years trying to study neuroscience in the United States when she landed on an internet forum where a bunch of scientists were all looking for the same thing: access to academic journal articles that were behind paywalls. That’s the moment the very simple, but enormously powerful, website called Sci Hub was born.

The site holds over 88 million articles and serves up about a million downloads to people in practically every country on the globe. We travel to Kazakhstan to meet the mysterious woman behind it all and to find out what it takes to make everything we know about anything available to anyone anywhere, for free.

Special thanks toVrindra Bhandari, Balázs Bodó, Stephen Buranyi, Ian Graber-Stiehl, Joel Joseph, Noorain Khalifa, Aparajita Lath, Steve McLaughlin, Marcia McNutt, Randy Scheckman Tanmay Singh, Deborah Harkness, Joe Karaganis, Lawrence Lessig, Glyn Moody, and Steven Press.

Episode Credits:Reported by - Eli Cohen
Reporting help from - Karishma Mehrotra
Produced by Simon Adler
with help from - Eli Cohen
Original music and sound designed by - Simon Adler
Mixing by - Jeremy Bloom
Edited by - Alex Neason

Our newsletter comes out every Wednesday. It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!

Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.

Radiolab is on YouTube! Catch up with new episodes and hear classics from our archive. Plus, find other cool things we did in the past — like miniseries, music videos, short films and animations, behind-the-scenes features, Radiolab live shows, and more. Take a look, explore and subscribe!

Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.

Leadership support for Radiolab’s science programming is provided by the Gordon and Betty Moore Foundation, Science Sandbox, a Simons Foundation Initiative, and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

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Huberman Lab

Podcast Notes Key Takeaways * Different hairs on your body have different lengths of growth phases (for example, hair on the head will grow for 2-8 years, and hair on the eyebrows will fall out every few months) + The rate of hair growth is relatively stable across hair – what differs is the length of the growth phase * Microneedling procedures, PRP injections, and Minoxidil all center around the general idea of increasing blood flow, increasing oxygen and delivery of nutrients, or increasing inflammation just enough locally to set off a cascade of regrowth * Combination treatments that combine a mechanical stimulus (such as microneedling) with chemical stimulus (such as minoxidil) will always be better than either alone + But be realistic, it’s unlikely to grow a full head of hair again if you are bald * People are highly individual in response and side effects to hair growth treatments – start with minimum effective dose and be patient with experimentation time * Androgens (especially DHT) are potent inhibitors of IGF-1 and cyclic AMP which stimulate hair growth

Read the full notes @ podcastnotes.org

In this episode, I explain the biology of hair, hair growth, why hair growth slows and what cause hair to stop growing and/or “fall out.” I discuss the essential role of hair stem cells and other supporting biological factors for healthy hair growth. Then I describe various approaches (mechanical and chemical) to slow hair loss by increasing blood flow to hair stem cells, including minoxidil, tadalafil, PRP, microneedling, Botox and ketoconazole treatments. I also discuss how age-related hormone changes cause hair loss and explain the effectiveness of treatments such as caffeine, saw palmetto, growth hormone, finasteride and dutasteride. For all hair growth options, I describe potential side effects, how soon to expect results and the amount of hair regrowth to expect and I highlight effective combination treatments for hair regrowth even in hair “dead” (bald) zones. For many listeners, thinning, brittle hair, or pattern baldness are a source of anxiety and stress. This episode explains the mechanisms underlying hair regrowth tools and the science behind them so that you can evaluate potential treatments and associated side-effect profiles and select the best one(s) for you.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Helix Sleep: https://eightsleep.com/huberman
HVMN: https://hvmn.com/huberman
ROKA: https://roka.com/huberman
LMNT: https://drinklmnt.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Hair
(00:04:13) Sponsors: Helix Sleep, HVMN, ROKA
(00:08:04) Psychological States & Hair
(00:13:19) Hair Anatomy & Stem Cells
(00:26:05) 3 Phases of Hair Growth
(00:35:40) Sponsor: AG1 (Athletic Greens)
(00:36:55) Minoxidil & Blood Flow
(00:45:37) Increase Blood Flow: Massage, Tadalafil, Platelet-Rich Plasma (PRP), Microneedling
(00:56:10) Microneedling, Minoxidil & “Dead Zones”
(01:00:13) Sponsor: LMNT
(01:01:25) Botox Treatments
(01:06:27) Androgens, Hair Growth & Pattern Hair Loss; Scalp vs. Beard Hair
(01:15:46) Topical Caffeine & Slowing Hair Loss
(01:21:06) IGF-1: Growth Hormone & Sermorelin; Insulin Sensitivity: Myo-Inositol
(01:25:52) Iron & Hair Growth
(01:27:04) 5-Alpha Reductase & Saw Palmetto; Curcumin
(01:33:22) Ketoconazole & Offsetting Hair Loss
(01:38:46) Topical & Oral Finasteride
(01:51:00) Post- Finasteride Syndrome
(01:56:01) Dutasteride
(01:58:53) Mechanical & Chemical Stimulation for Hair Growth
(02:02:46) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Modern Wisdom

Podcast Notes Key Takeaways * People live out all of the potential downsides in the mere reflection of what other people will think about them in the future, should they fail * Shame only exists in the shadows; identify when you have the hesitation to confront something and ask yourself why you may be experiencing that hesitation * The difference between successful people and the most successful people is that the most successful people say no to almost everything * Success comes down to doing the obvious thing for an extraordinary period of time without convincing yourself that you are smarter than you are * The first step to achieving a massive dream is conquering tiny impulses * Opportunities only look like opportunities in the rear-view mirror; today, they only seem like risk * Most of the pain that people experience is purely in their own minds * There is always someone who has had it worse and has done it better * Power follows the blame finger: you give power to wherever you point the blame to * Pain moves people far more effectively than pleasure does * We commonly sacrifice the thing we want for the thing that is supposed to get it * Three most common traits that hyper-successful people have: a superiority complex, insecurity, and impulse control * What is the thing that you can do longer than anyone else where to them it looks like work, and to you, feels like play? * Constantly ask yourself: “What are we optimizing for?” * Try to be directionally correct instead of trying to be absolutely correct

Read the full notes @ podcastnotes.org

Alex Hormozi is a founder, investor and an author.

Alex's Twitter has been one of my favourite sources of great insights over the last year. Today we get to go through some of my favourite lessons from him about life, human behaviour, psychology, business and resilience. This is really good.

Expect to learn how your ego is keeping you poor, why you never need to care about what anyone else thinks of you, why having a life that sucks is actually a blessing, whether most easy opportunities are just distractions, how to conquer your tiny impulses, why you are built to deal with things being hard, how to beat anyone who ever copies you and much more...

Sponsors:

Website in 10 MINUTES, no coding skills required: https://hostinger.com/modernwisdom (code MODERNWISDOM for 10% off)

Get 15% discount on Craftd London’s jewellery at https://craftd.com/modernwisdom (use code MW15)

Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied)

Extra Stuff:

Follow Alex on Twitter - https://twitter.com/AlexHormozi

Follow Alex on Instagram - https://www.instagram.com/hormozi/

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Infinite Loops

Podcast Notes Key Takeaways * Check out Infinite Loops Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

This week, we’re delighted to welcome Ed Latimore back for his second Infinite Loops appearance.

Ed is a best-selling author, former professional heavyweight boxer, competitive chess player, Physics graduate, father, and husband. He joins us to discuss stoicism, progress & pain, demonstrating authenticity, being liked vs. being respected, and a whole lot more.

Important Links:

Ed’s Twitter
Ed’s website
Ed’s Substack
Ed’s first Infinite Loops appearance

Show Notes:

New child; new house; new book
How Ed’s new book has developed
Humor and progress
Understanding addiction
Being liked vs being respected
“Stoicism found me”
Is progress possible without pain?
“Humans are very bad at the future”
Demonstrating authenticity
Being cast as a father figure
What’s next for Ed
Ed’s three step process for self-improvement
“I don't think any situation has ever gotten worse because someone has good manners.”

Books Mentioned:

The Founders: The Story of PayPal and the Entrepreneurs who Shaped Silicon Valley; by Jimmy Soni
The Art of Learning: An Inner Journey to Optimal Performance; by Josh Waitzkin
Can't Hurt Me: Master Your Mind and Defy the Odds; by David Goggins
The Subtle Art of Not Giving a F*ck: A Counterintuitive Approach to Living a Good Life; by Mark Manson

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Pod of Jake

Podcast Notes Key Takeaways * OpenStore’s mission is to reinvent e-commerce to allow for the serendipitous discovery of products in a way that obviates the need to shop in the real world * Optimally, a fundraising round should directly de-risk a certain aspect of the business * People are more emotional about selling their business compared to selling their future cash flows * There is a fixed cost of pain when building a start-up; you might as well amortize the same pain across the biggest possible vision * Having success in the first vertical is so hard that most people lose the energy, enthusiasm, and time to conquer other verticals in the future * From day one of running a company, identify your goal and work backward from it * Automate the processes that can be automated to maximize scalability * Successful companies work in person and have a critical density of talent where everyone works in the same room * The art of company building is to find people whose talent is not yet appreciated by the rest of the world and who have incredible potential * A question every entrepreneur must consider: “Does your company have the best possible people working against the most important challenges?”

Read the full notes @ podcastnotes.org

Keith is the CEO & Co-Founder of OpenStore and a General Partner at Founders Fund. He is an experienced technology executive and entrepreneur, a prolific investor, and a self-described contrarian. Keith previously served as a General Partner at Khosla Ventures. Before that, he was COO at Square and served in influential roles at LinkedIn. He also co-founded Opendoor. Keith began his career in technology as a senior executive at PayPal. He has since invested early in many great companies including YouTube, Airbnb, Palantir, DoorDash, Stripe, Quora, Yammer, Affirm, Eventbrite, and many others. He also served as a Board Member from inception to IPO at Yelp and Xoom. Follow Keith on Twitter @rabois.

[0:00] - OpenStore's early momentum and fundraising strategy

[5:35] - How an decentralized department store could unlock eCommerce growth

[12:33] - Introducing OpenStore Drive and why it is great for Shopify store owners

[16:49] - OpenStore's horizontal approach and why Keith believes it is best

[18:41] - OpenStore’s business acquisition strategy and thoughtful process design

[24:09] - How learnings from OpenStore’s initial acquisitions have led to improvements

[28:56] - Why OpenStore’s business is resilient in various macroeconomic environments

[35:06] - Acquisition offers and accept rates as metrics and countermetrics at OpenStore

[38:45] - Introducing Gumdrop which matches long-tail influencers to long-tail SKUs

[41:40] - The advantages of aggregation that benefit OpenStore’s business model

[45:19] - Building a great company culture; finding & developing undiscovered talent

[51:11] - The most high-leverage activities Keith allocates time to as OpenStore's CEO

homeofjake.com

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Recode Decode

A few weeks ago, President Biden was in the Netherlands, where he asked the Dutch government to restrict export from a company called ASML to China. ASML is the only company in the world that makes a specific machine needed to make the most advanced chips. Apple couldn’t make iPhone chips without this one machine from the Netherlands’ biggest company. ASML doesn’t just shape the Dutch economy—it shapes the entire world economy. How did that happen?
Chris Miller, Tufts professor and author of Chip War: The Fight For The World’s Most Critical Technology walked me through a lot of this, along with some deep dives into geopolitics and the absolutely fascinating chip manufacturing process. This one has everything: foreign policy, high powered lasers, hotshot executives, monopolies, the fundamental limits of physics, and, of course, Texas. Here we go.

Links:
US issues sweeping restrictions on chip sales to China
Japan and the Netherlands join US with tough chip controls on China
Pat Gelsinger came back to turn Intel around — here’s how it’s going

Transcript:
https://www.theverge.com/e/23342471

Credits:
Decoder is a production of The Verge and part of the Vox Media Podcast Network.
It was produced by Creighton DeSimone and Jackie McDermott and it was edited by Callie Wright.
The Decoder music is by Breakmaster Cylinder. Our Editorial Director is Brooke Minters and our Executive Director is Eleanor Donovan.
Learn more about your ad choices. Visit podcastchoices.com/adchoices

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The Underworld Podcast✓Claim

Podcast Notes Key Takeaways * Sean searches for a $1 billion meth lab hidden in the jungles of Myanmar and writes an article for GQ magazine * Kings Roman’s Casino is a unique city carved out of the jungle where Thailand and Lao meet on the Mekong River + The US Treasury has placed the casino under official sanctions due to its association with illicit activities * Southeast Asian drug syndicates earn 2-3 times more than Mexican cartels in the cocaine trade * Tse Chi Lop, a Canadian Chinese kingpin, allegedly runs a drug empire worth nearly $18 billion * “The Machine”: A massive meth lab hidden in Myanmar’s forests, operated by skilled chemists from Taiwan and protected by bribed army officers and militants * Once primarily known for opium production, the Golden Triangle region now has rebel-held mega labs producing synthetic drugs, driving a global drug crisis affecting millions * In his search for the meth lab, Sean travels deep into rebel-held territory, encounters dangerous situations, and even sleeps rough on the banks of the Mekong River * British colonization of Burma in the 19th century led to the exploitation of natural resources and the local labor force + The cool climate of the Northern Highlands made it an ideal location for growing opium poppies * George Orwell’s experience and observations in Rangoon influenced his works, such as 1984 and Animal Farm * Methamphetamine was first synthesized by a German scientist in 1887 and was widely used during WWII by German and Japanese soldiers * The Golden Triangle region shifted from opium production to methamphetamine in recent years * Myanmar’s Shan State and Wa region are central to meth production due to their remote and poorly governed locations * Drugs are smuggled primarily through India and China, exploiting their porous borders with Myanmar * Methamphetamine from the Golden Triangle has spread to countries such as Singapore, Japan, and Australia, contributing to growing drug problems + The meth trade exacerbates criminality, corruption, and ethnic conflicts in Myanmar, particularly in the Shan State * On assignment in search of a billion-dollar meth lab, Sean Williams wore disguises, evaded law enforcement, and navigated tense situations in villages and with local teenagers * Despite embarking on a second trip and chasing cartels across the country, Sean and his team failed to locate the meth lab but gained valuable lessons and insights from the experience

Read the full notes @ podcastnotes.org

The biggest drug cartel in the world isn't Mexican, or Colombian. It's Asian. Buried deep in the Burmese jungle are networks of cutting edge meth labs, guarded by rebels and run by kingpins so powerful they make El Chapo look like a corner boy. In 2019, Underworld cohost Sean Williams went looking for one of the billion dollar meth labs spending months on the Mekong, in lawless casinos and hunting a drug industry bigger than any other on earth...and now he's a dad!
Learn more about your ad choices. Visit megaphone.fm/adchoices

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Huberman Lab

Podcast Notes Key Takeaways * Stress and your perception of stress impact your brain and body * Managing stress is about finding the ‘stress shields’ that fit them, feel right, and they believe – for example, breathwork, reminding yourself of past successes, distance from stress, calling on confidant, etc. * Stress can lead to obesity and insulin resistance: there’s a tendency to a greater reward response from food – the more insulin resistant you are, the more your reward center lights up during stress * Cravings hijack the prefrontal cortex – body scan draws attention inward toward interoception and away from external stimulus * At our core, we want to know with certainty what’s going to happen and control our future – being comfortable with uncertainty is a huge stress resilience factor * Tips to navigate stress: journal to create a coherent narrative; practice radical acceptance, learning when to paddle and when to give into the wave; practice breathwork and body scans to increase interoception and reduce exteroception; use exercise to burn negative energy and improve stress resilience

Read the full notes @ podcastnotes.org

In this episode, my guest is Elissa Epel, Ph.D., professor and vice chair of the department of psychiatry at the University of California San Francisco (UCSF) and the author of a new book entitled The Stress Prescription. We discuss her work showing how stress impacts mood, eating behavior, mental health, physical health, and aging. She explains stress intervention tools using “top-down” techniques (e.g., radical acceptance, mindfulness, reframing), body-based methods (e.g., breathwork) including the Wim Hof Method, exercise, meditation, body scans, and environmental shifts proven to help people cease unhealthy rumination patterns. We discuss how stress can positively impact psychology and sense of purpose, how stress affects cellular aging, how our narratives of stressful events impact our mood and biology, and how to effectively reframe stress. She explains science-based techniques to break stress-induced cycles of craving and overeating and thereby improve insulin sensitivity and metabolic health. Dr. Epel provides a wide range of tools shown to be effective in reducing stress and improving various aspects of our health.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Thesis: https://takethesis.com/huberman
Eight Sleep: https://eightsleep.com/huberman
HVMN: https://hvmn.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Elissa Epel
(00:02:17) Sponsors: Thesis, Eight Sleep, HVMN, Momentous
(00:06:18) Stress; Effects on Body & Mind
(00:12:50) Tools: Overthinking & Stress
(00:15:37) Acute, Moderate & Chronic Stress, Breathing
(00:21:23) Stress Benefits, Aging & Cognition; Stress Challenge Response
(00:31:04) Sponsor: AG-1 (Athletic Greens)
(00:32:19) Tool: Shifting Stress to Challenge Response, “Stress Shields”
(00:37:400 Stress, Overeating, Craving & Opioid System
(00:48:55) Tools: Breaking Overeating Cycles, Mindfulness
(00:54:44) Soda & Sugary Drinks
(01:00:51) Smoking, Processed Food & Rebellion
(01:05:29) Sponsor: InsideTracker
(01:06:47) Tools: Mindfulness, Pregnancy & Metabolic Health
(01:14:11) Body Scan & Cravings
(01:17:28) Tool: Meditation & Aging; Meditation Retreats
(01:23:35) Meditation, Psychedelics & Neuroplasticity
(01:26:02) Mitochondrial Health, Stress & Mood
(01:29:49) Chronic Stress & Radical Acceptance, “Brick Wall”
(01:37:57) Tool: Control, Uncertainty
(01:45:25) Stress Management, “Skillful Surfing”
(01:50:25) Narrative, Purpose & Stress
(01:52:49) Breathwork, Wim Hof Method, Positivity & Cellular Aging
(02:03:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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HBR IdeaCast✓Claim

Podcast Notes Key Takeaways * Check Out HBR IdeaCast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

How do you solve the world's toughest problems? Or find the next big thing in tech? Lots organizations fail to explore and take big bets on new ideas because they can't tolerate the mess of experimentation and the fear of failure. At X, Alphabet's dedicated innovation factory, they don't have that problem, and Astro Teller, Captain of Moonshots at X, can explain why. Undertaking projects on everything from rural communication to ocean health to machine learning, he and his teams operate with different creative mindsets and decision-making principles than many of us. He spoke with host Alison Beard at HBR at 100: Future of Business live virtual conference.

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Starting Greatness with Mike Maples

Podcast Notes Key Takeaways * Check out Starting Greatness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Startup founders dealt with uncertainty, stress and trauma in the wake of the run on Silicon Valley Bank, but the most important lessons from this crisis never showed up in social media. In this lesson of greatness, Mike Maples, Jr of FLOODGATE calls on the actions of a variety of founders who showed incredible courage and competence to showcase three crucial lessons for founders for how to deal with another potential crisis: Scenario planning, financial agility, and crisis communication.

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Huberman Lab

Podcast Notes Key Takeaways * The dopamine system doesn’t care about the specific goal or pursuit – it’s about pursuing anything, healthy or not * If we expose regularly expose ourselves to things that trigger high levels of dopamine release, we will lower our baseline levels of dopamine over time * From a thought to action: desire for things increases dopamine, level of dopamine drops below baseline, drop below baseline triggers motivation to bring dopamine level back up by pursuing the thing you wanted in the first place + You want to relieve the pain of not having that thing * Three fundamentals of the dopamine system drive you toward learning: (1) desire – I want that; (2) motivation – drives you toward action; (3) reward or lack of reward * Addictions are the progressive narrowing of things that give us pleasure + “It’s both the duration between desire and effect (rewarding property of dopamine that are experienced) that teach the system to want and expect short gaps, which makes it hard to pursue things that take longer.” – Dr. Andew Huberman * If you enjoy an activity, protect that feeling by making sure you don’t attach reward or other dopamine-releasing behaviors to that behavior + If you stack too many dopamine-releasing things to something you already enjoy, you may experience less interest/desire/motivation to do that thing * To overcome procrastination: figure out something that sucks (but is safe) to steepen the trough which will bring you back to baseline dopamine faster + For example cold shower/water immersion – this will remind your brain you can do hard things

Read the full notes @ podcastnotes.org

In this episode, I explain how dopamine dynamics — meaning changes and interactions between our baseline and peak levels of dopamine drive our cravings and sense of motivation. I also explain how to leverage dopamine dynamics to overcome procrastination. I cover behavioral, cognitive, nutrition-based and supplementation-based tools to optimize baseline and peak dopamine levels to ensure a persistently motivated state. I also discuss how to boost motivation when you are in a rut, why you might not want to stack behaviors/substances that spike dopamine and how build and maintain a “growth mindset” for pursuing goals of any kind. Dopamine is an incredibly powerful neuromodulator involved in basic functions (e.g., hunger, romantic attraction, etc.) and feats of cognitive and physical performance; by understanding the dynamics of dopamine, listeners ought to be better positioned to overcome procrastination, maintain motivation, and improve confidence.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Helix Sleep: https://helixsleep.com/huberman
WHOOP: https://join.whoop.com/huberman
ROKA: https://roka.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dopamine
(00:02:32) Sponsors: Eight Sleep, WHOOP, ROKA, Momentous
(00:06:27) Dopamine Brain Circuits
(00:14:53) Goals & Addiction
(00:17:13) Dopamine Dynamics, “Wave Pool” analogy
(00:20:28) Craving, Motivation, Pursuit & Reward Prediction Error
(00:28:26) Sponsor: AG1 (Athletic Greens)
(00:29:40) Feedback Cues & Reward Contingent Learning, “Scoreboard”
(00:37:40) Addiction; Pleasure & Pain Imbalance
(00:44:55) Dopamine Release & Addictive Substances/Behaviors
(00:50:43) Addiction Recovery, Binding Behaviors
(00:53:25) Tools: Maintain Baseline Dopamine Levels
(01:02:08) Sponsor: InsideTracker
(01:03:26) Tool: Deliberate Cold Exposure & Dopamine
(01:09:38) Prescriptions & Supplementation: L-Tyrosine, Mucuna Pruriens
(01:18:58) Dopamine Trough Recovery, Postpartum Depression
(01:23:31) Dopamine Dynamics, “Dopamine Stacking”; Intrinsic Motivation
(01:38:10) Making Effort the Reward, Growth Mindset
(01:41:49) Tool: Overcome Procrastination
(01:52:16) Tool: Meditation & Procrastination
(01:57:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media
Title Card Photo Credit: Mike Blabac
Disclaimer

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Econtalk

Podcast Notes Key Takeaways * Learn how to learn from those you disagree with or even offend you; see if you can find the truth in what they believe * When there are two sides to an issue, consider where the third side might be * Don’t measure your life with someone else’s ruler; figure out what ruler you want to use and create your standards * Ignore what others may be thinking of you because they are not thinking of you * Do not ruin an apology with an excuse * Do not aim to be the best, aim to be the only * When trying to make a decision and presented with several choices, consider the value of uniqueness * Our views should be evidence-based and not based on the imaginary harms the technology potentially causes to the hypothetical third person * Kevin Kelly attaches a non-zero probability to the singularity, but it should not be something that disproportionately influences how we regulate and think about AI today * AI shows us that things we thought were special and unique to humans can be replicated * “This vision of superhuman intelligence is mythical, if not religious. It’s a belief.” – Kevin Kelly * The auto-complete replication processes that these AIs are doing today are not anywhere near consciousness or self-awareness

Read the full notes @ podcastnotes.org

Photographer, author, and visionary Kevin Kelly talks about his book Excellent Advice for Living with EconTalk's Russ Roberts. His advice includes how to have a deep conversation, why it's better to control time than money--and whether, in the end, we should give advice in the first place. Other topics of discussion include the right object of our aspirations, the reason for optimism when it comes to technology, and why Kelly is not worried about AI.

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My First Million

Podcast Notes Intro * Shaan Puri (@ShaanVP) walks us through his tried and tested template for pitching your business idea to potential investors. Follow along on YouTube for the visuals. * Additional context: This template is in slideshow format, otherwise known as a pitch deck. To explain each slide in further detail, Shaan often refers to the company Shuni, which is an app dedicated to sleep and meditation.

Read the full notes @ podcastnotes.org

Episode 436: In a special Friday episode, Shaan Puri (@ShaanVP) gives a special masterclass on his pitch deck that has raised millions from investors. Go to the MFM YouTube channel to see examples.
Want to see more MFM? Subscribe to the MFM YouTube channel here.
SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com

Links:
shaanpuri.com/deck
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.

Show Notes:
(01:35) - Title
(05:41) - Data/personal story
(07:30) - Future vision
(10:30) - Hero metric
(14:15) - Track record
(16:30) - Sweeten the pot

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * We will look back on GPT-4 as we do the early computers: buggy, slow, room for improvement, but nonetheless a monumental achievement * Progress is a continuous exponential; very rarely is there “a single moment” where technology crosses the rubicon * OpenAI is building in public because they think it is important for the world to get access to this technology early and to shape the way it is going to be developed * Better alignment techniques lead to better capabilities, and vice versa * Ideally, the world comes together, discusses, and agrees on where it wants to draw the boundaries on the GPT system * It is possible that GPT-4 is the most complex software object that humanity has produced, and it will be trivial in a couple of decades * Maybe AGI is never achieved; maybe narrow AI just continues to make humans better * There is some chance of an AGI destroying humanity, and it is important to acknowledge that chance because if we do not discuss and treat it as potentially real, then we will not put enough effort into solving it * AGI could happen soon or far in the future; the takeoff speed from the initial AGI to more powerful successor systems could be slow or fast * It would be “crazy” to not be a little bit afraid of AGI * Sam worries about the entities creating AGIs that do have incentives to capture unlimited value * “I definitely grew up with Elon as a hero of mine. Despite him being a jerk on Twitter or whatever, I’m happy he exists in the world. But I wish he would do more to look at the hard work we’re doing to get this stuff right.” – Sam Altman * These AI systems will make a lot of jobs go away, as is true for every technological revolution, and will also create many new types of jobs that we cannot yet imagine * Over the next several decades, the two dominant changes will be the reduced cost of intelligence and energy * “Listening to advice from other people should be approached with great caution.” – Sam Altman

Read the full notes @ podcastnotes.org

Sam Altman is the CEO of OpenAI, the company behind GPT-4, ChatGPT, DALL-E, Codex, and many other state-of-the-art AI technologies. Please support this podcast by checking out our sponsors:
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GPT-4 Website: https://openai.com/research/gpt-4

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OUTLINE:
Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.
(00:00) - Introduction
(08:41) - GPT-4
(20:06) - Political bias
(27:07) - AI safety
(47:47) - Neural network size
(51:40) - AGI
(1:13:09) - Fear
(1:15:18) - Competition
(1:17:38) - From non-profit to capped-profit
(1:20:58) - Power
(1:26:11) - Elon Musk
(1:34:37) - Political pressure
(1:52:51) - Truth and misinformation
(2:05:13) - Microsoft
(2:09:13) - SVB bank collapse
(2:14:04) - Anthropomorphism
(2:18:07) - Future applications
(2:21:59) - Advice for young people
(2:24:37) - Meaning of life

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Knowledge Project

Podcast Notes Key Takeaways * Check out The Knowledge Project Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Visionary technology and business leader Nathan Myhrvold just might be the most interesting person in the world, and in this episode of The Knowledge Project he dives deep into some of the most pressing questions facing our world today. Where will technology take us in the future? Should we trust artificial intelligence? Where have we gone wrong in protecting our planet? How do we reverse the effects of what we’ve already done? Myhrvold answers all these and much, much more. Myhrvold is a prominent scientist, technologist, inventor, author, and food photographer, and the former Chief Technology Officer at Microsoft. He’s also the co-founder of patent portfolio developer Intellectual Ventures, the principal author of the culinary book Modernist Cuisine: The Art and Science of Cooking, part of a team that won first place at the World Barbecue Championships, and he completed his postdoctoral fellowship under legendary theoretical physicist Stephen Hawking. --

Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Nudge - Marketing Science Simplified✓Claim

Podcast Notes Key Takeaways * Check Out the Nudge Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Ever worried about someone stealing your phone at the beach? Well, there’s one thing you can do to make your phone 4x safer. It involves using a psychology-inspired principle to change behaviour. On this show, you’ll learn what it is, and why it’s important to marketers. Today, Nancy Harhut and I will cover five more marketing principles. Plus, I’ll share my real-world experiments to reveal which principles work, and which don’t.

Try HubSpot for free: https://hubspot.sjv.io/jWq4k6
Consistency experiment: https://bit.ly/3sABZTU
Input bias experiment: https://bit.ly/3sEPFgC
Framing experiment: https://bit.ly/3TMKgA2
Information gap experiment: https://bit.ly/3DiGasA
Authority bias experiment: https://bit.ly/3sF0G1A
Nancy’s book: https://amzn.to/3DZTl23
Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list
Take my marketing course: https://science-of-marketing.teachable.com/

Using Behavioral Science in Marketing: Drive Customer Action and Loyalty by Prompting Instinctive Responses

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Huberman Lab

Podcast Notes Key Takeaways * Prevention of atherosclerosis (the leading cause of death in the world): (1) maintain healthy blood pressure (120/80); (2) don’t smoke anything; (3) measure ApoB and lipoproteins starting in the 20s * ApoB is far superior for predicting risk than LDL: LDLc measures the total concentration of cholesterol in LDL; APoB measures the number of them + “There is no ambiguity that ApoB is causally related to atherosclerosis.” – Dr. Peter Attia + Most of the cholesterol you eat, you don’t absorb * Unequivocal truths for brain health: sleep matters, lower LDL cholesterol, and ApoB is better, not having type 2 diabetes matters, exercise matters (low-intensity cardio, strength, interval training) + Avoiding head injuries is also important; research on the use of hyperbaric oxygen immediately following head injury is emerging (but don’t consider hyperbaric oxygen as useful for anything else) * “Some component of your training needs to be stressing type 2 fibers. You have to be doing strength training that taxes those fibers.” – Dr. Peter Attia + To offset the probability of falls you have to be able to jump and land safely – after a fall at minimum your quality of life is impacted, on the far end risk of death increases by 15-30% + The Hallmark of aging in muscle is the degradation of type 2 muscles (fast twitch) – we lose speed, then strength, then size; you have to train jumping and landing * Pillars of longevity through physical health: (1) strength, (2) stability, (3) aerobic efficiency, (4) aerobic peak output/VO2 max * Emotional health is potentially the most important factor in health – an infinite lifespan if you’re miserable is worthless; poor emotional health is a risk factor for every marker of health + Redirect negative self-talk: communicating lovingly with yourself is critical for your ability to not beat up those around you as well * The goal is not perfection – you will set yourself up for failure if your goal is to be perfect, instead focus on being the best at repairing damage when you cause it

Read the full notes @ podcastnotes.org

In this episode, my guest is Peter Attia, M.D. He completed his medical and advanced training at Stanford University School of Medicine, Johns Hopkins School of Medicine and the National Institutes of Health (NIH). Dr. Attia is host of the health and medicine podcast, The Drive, and the author of a new book, “Outlive: The Science & Art of Longevity,” which examines disease prevention and healthy aging, including emotional health. He explains the leading causes of death worldwide and how to measure one’s risk of death and mitigate each risk factor. Dr. Attia shares how, in addition to blood-based markers of lipids and hormones, there are behavioral measures and interventions, and key aspects of emotional health (i.e., relationships, emotional stability, purpose, etc.) that fundamentally impact our physical health and longevity, and how to assess and adjust our emotional health. This episode is rich with actionable information related to disease screening and biomarker testing, nutritional, exercise, behavior and prescription-based tools that area useful to all people regardless of age, male or female, and that can significantly improve vitality, health and lifespan.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
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Supplements from Momentous
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Timestamps
(00:00:00) Dr. Peter Attia
(00:03:22) Sponsors: Eight Sleep, LMNT, HVMN, Momentous
(00:07:34) Lifespan vs. Healthspan
(00:10:54) “4 Horseman of Death”, Diseases of Atherosclerosis
(00:14:44) Tool: Hypertension & Stroke, Blood Pressure Testing
(00:23:14) Preventing Atherosclerosis, Smoking & Vaping, Pollution
(00:32:24) Sponsor: AG1 (Athletic Greens)
(00:33:29) Cholesterol, ApoB
(00:42:21) Cholesterol Levels, LDL & ApoB Testing
(00:49:29) ApoB Levels & Atherosclerosis, Causality
(01:01:06) ApoB Reduction, Insulin Resistance, Statins, Ezetimibe, PCSK9 Inhibitors
(01:12:30) Monitoring ApoB
(01:17:12) Sponsor: InsideTracker
(01:18:30) Reducing Blood Pressure, Exercise & Sleep
(01:20:50) High Blood Pressure & Kidneys
(01:23:11) Alcohol, Sleep & Disease Risk
(01:31:21) Cancer & Cancer Risks: Genetics, Smoking & Obesity
(01:39:47) Cancer Screening & Survival
(01:44:17) Radiation Risks, CT & PET Scans
(01:48:48) Environmental Carcinogens
(01:52:11) Genetic & Whole-Body MRI Screening, Colonoscopy
(01:58:47) Neurodegenerative Diseases, Alzheimer’s Disease, ApoE
(02:08:08) Alzheimer’s Disease & Amyloid
(02:13:58) Interventions for Brain Health, Traumatic Brain Injury (TBI)
(02:21:26) Accidental Death, “Deaths of Despair”, Fentanyl Crisis
(02:31:20) Fall Risk & Stability, 4 Pillars of Strength Training
(02:41:05) Emotional Health
(02:53:45) Mortality & Preserving Relationship Quality
(03:02:20) Relationships vs. Outcomes, Deconstructing Emotions
(03:09:34) Treatment Centers, Emotional Processing & Recovery
(03:16:34) Tool: Inner Monologue & Anger, Redirecting Self-Talk
(03:27:37) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Modern Wisdom

Gurwinder Bhogal is a programmer and a writer.

Gurwinder is one of my favourite Twitter follows. He’s written yet another megathread exploring human nature, cognitive biases, mental models, status games, crowd behaviour and social media. It's fantastic, and today we go through some of my favourites.

Expect to learn why asking questions is the most selfish thing you can do, why people create hatred in an attempt to feel love, the real danger of censorship, why it's more important to avoid being wrong than try to be right, what postjournalism is and why you need to understand it, how to win every debate even if you lose, why you should never take an internet insult personally and much more...

Sponsors:

Get a Free Sample Pack of all LMNT Flavours with your first box at https://www.drinklmnt.com/modernwisdom (automatically applied at checkout)

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Get 20% discount on House Of Macadamias’ nuts at https://houseofmacadamias.com/modernwisdom (use code MW20)

Extra Stuff:

Check out Gurwinder's Substack - https://gurwinder.substack.com/

Follow Gurwinder on Twitter - https://twitter.com/G_S_Bhogal

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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What Got You There with Sean DeLaney

Podcast Notes Key Takeaways * Understand the difference between work and play: work is anything that is energy-depleting, while play is energy-regenerating * In life, there is a big difference between what you are good at and how you are wired * If you do not love what you do, you will probably not stick with it even if you excel at it * No amount of pleasure from lifestyle inflation can offset a lack of purpose * What minimalism is to your things, slow living is to your time * Concepts of intentional living include voluntary simplicity, downshifting, minimalism, digital minimalism, decluttering, financial independence, and lifestyle design * Epiphanies happen when you read something that you intuitively knew, but aren’t unable to put into words until then * Always consider the second and third-order effects of an action, and try to make that action positively reinforce other goals that you have * As you psychologically develop, how you relate to what you know changes * Quality is a byproduct of quantity; you will get better at something the more that you do it * A synthesizing mind is a mind with the capacity to take in a lot of information, reflect on it, and then organize it in a way that is useful to you that also proves useful to others * When you reflect on a situation or period of time, oftentimes you realize things that you did not realize when you were in the midst of it * Having awareness of your thoughts and understanding that you are not your thoughts changes your relationship with them

Read the full notes @ podcastnotes.org

Kyle Kowalski is the Funder of Sloww.co (one of my favorite websites for synthesized knowledge + wisdom!)

Kyle is an ex-marketing executive turned corporate dropout and solopreneur who found and created his life purpose after an existential crisis. In one sentence, his purpose is synthesizing lifelong learning that catalyzes human development (LFG!!!). In a nutshell, Kyle is learning why and how to live and publicly sharing what he learns along the way at Sloww.co. Thinking is his passion—but he's not a professor, philosopher, psychologist, sociologist, anthropologist, scientist, or guru. He's an interdisciplinary dot connector across all those humans and many more. Kyle does all the homework—researching, curating, reading, note-taking, summarizing, synthesizing, writing, creating, and sharing. You get all the highlights—so you spend less time on all those things and more time learning, practicing, and mastering. About Sloww: Sloww shares the art of living with students of life. Sloww currently has a Premium membership with 1,000+ global members, a weekly email newsletter with 10,000+ subscribers, a social media following of 30,000+, and a website with 60,000+ monthly visitors (5,000,000+ lifetime pageviews). Kyle's 10 Most Life Changing Ideas Ikigai 2.0 Guidebook Watch on YouTube JOIN ME for 2 LIVE VIRTUAL EVENTS!

Live Podcast with David Senra, Host of Founders Podcast on March 15th at 2pm ET!

Register HERE, spots are limited and even if you can’t attend live if you register you’ll receive a video of the interview & Q&A!

“10 Mindsets to Radically Transform Your Life” Webinar on March 23rd at 1pm ET!

Register HERE to learn the 10 most impactful mindsets I’ve uncovered working with and learning from the world’s most successful people!

I’ve studied hundreds of the world’s must successful people and compiled:13 Insights from the World’s Most Successful People – Click Here to get access

https://youunleashedcourse.com/

You Unleashed is an online personal development course created by Sean DeLaney after spending years working with and interviewing high achievers.The online course that helps you ‘Unleash your potential’!

You Unleashed teaches you the MINDSETS, ROUTINES and BEHAVIORS you need to unleash your potential and discover what you’re capable of.

You know you’re capable of more and want to bring out that untapped potential inside of you.

We teach you how.

Enroll Today!- Click Here

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My First Million

Podcast Notes Key Takeaways * There are four ways to frame a meeting with a company leader: + I am doing this, FYI + I am doing this, but I need your approval + I am trying to decide between A, B, or C. Can you help me think that through? + Remember that thing we agreed on? Here is what happened. * Company updates or memos should address “What, Why, and So What?” * Fierce nerds are all in on the thing they are pursuing; they do not have a social thing to fall back on, and lack the emotional maturity to separate themselves from the competition * Competition is deeply personal to fierce nerds; they are fully obsessed * Being well-read allows you to connect dots between seemingly unrelated things and create new things * Get closer to the truth by challenging each assumption in the argument * A leader must surround themself with people who are willing to tell them the uncomfortable truth

Read the full notes @ podcastnotes.org

In a special episode of My First Million, Shaan (@ShaanVP) talks about the nine things he learned from Emmett Shear - CEO of Twitch - who resigned today.
Want to see more MFM? Subscribe to the MFM YouTube channel here.
SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Invest Like the Best

Podcast Notes Key Takeaways * Many of the high-margin software businesses have no impact on society, and sometimes can even have a negative impact on society * Founders in the dynamism category are creating teams that are mission-oriented and interested in more than just making money; they want to build techno-optimist solutions for strategically important problems * It is important for society’s best players to choose good quests * It is best to lean into your passions and overinvest in them * We must encourage people to be “spikey” instead of only encouraging them to be “well-rounded” * In his early days at Founder Fund, Trae was looking to invest in a 21st-century reboot of Lockheed Martin; it did not exist, so he started it * If a company is going to work, each team member must leverage their own superpower to achieve the company’s audacious goal * The adversary must know that Anduril’s product will prevent their offensive from happening and that the defensive cost to prevent it is far lower than the offensive cost to launch it * “The DoD has done a really good job at creating theater around their innovation efforts.” – Trae Stephens * The big defense primes are effectively government agencies that respond to the incentives presented to them * Mimetic desire is the primary motivation for conflict in society because we are all going after the scarce resources that other people want * Working and learning about an industry in a supporting role is 100x better than graduate school * The first question that Trae Stephens asks in every pitch meeting is: “What is the origin story of this business?” * Ask yourself what you are uniquely suited to do to contribute to a greater good * We lose the wonders of virtue when we rely on ourselves as the source of all truth

Read the full notes @ podcastnotes.org

My guest this week is Trae Stephens. Trae is a partner at Founders Fund and co-founder and Executive Chairman of Anduril. Trae’s philosophy can be boiled down to finding good quests, which has led him to investing in businesses that work closely with the government on societally important issues. Clearly, that extends to co-founding Anduril and I would highly recommend listening to my Business Breakdowns episode on Anduril if you haven’t already. In this conversation, we discuss the importance of lobbyists, why the high-tech defense firms of the past became stale, and how he hunts for disagreeableness in founders. Please enjoy my conversation with Trae Stephens.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

Listen to Founders Podcast

Founders Episode 136 - Estee Lauder

Founders Episode 288 - Ralph Lauren

This episode is brought to you by Tegus, the modern research platform for leading investors. I’m a longtime user and advocate of Tegus, a company that I’ve been so consistently impressed with that last fall my firm, Positive Sum, invested $20M to support Tegus’ mission to expand its product ecosystem. Whether it’s quantitative analysis, company disclosures, management presentations, earnings calls - Tegus has tools for every step of your investment research. They even have over 4000 fully driveable financial models. Tegus’ maniacal focus on quality, as well as its depth, breadth and recency of content makes it the one-stop, end-to-end research platform for investors. Move faster, gather deep research to build conviction and surface high-quality, alpha-driving insights to find your differentiated edge with Tegus. As a listener, you can take the Tegus platform for a free test drive by visiting tegus.co/patrick.

Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.

Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.

Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.

Follow us on Twitter: @patrick_oshag | @JoinColossus

Show Notes

[00:03:17] - [First question] - Why Trae thinks most high-margin businesses are bad for society

[00:04:28] - What would he change to impact energy technology most if he were in charge

[00:06:18] - His investing focus on dynamism and mission-driven tech companies

[00:09:42] - Analyzing why relatively few people strive to make society-level advancements

[00:11:35] - What he’s done as a parent to enable his kids to develop passions

[00:12:41] - The most noteworthy adventures in his career

[00:14:41] - Founding Anduril and what it taught him about the tech industry

[00:18:40] - The cutting-edge of defense technologies today

[00:21:29] - What Shyam Sankar of Palantir taught him about defense tech

[00:23:34] - Why some of the biggest defense tech companies have stopped innovating

[00:28:29] - What he and Anduril have learned about sales and scaling in the public sector

[00:32:12] - Where lobbyists and decision makers play in to defense tech business models

[00:35:22] - His take on Peter Thiel’s notion that competition should be avoided

[00:38:24] - The importance of being psychologically disagreeable when building a start-up

[00:39:54] - The origin story that stands out the most from companies he has interviewed

[00:41:12] - How he developed an investor mindset on his unorthodox path to the venture world

[00:43:57] - What he has learned from playing supporting roles and aligning with great leaders

[00:46:11] - Important but uncommon lessons about entrepreneurship

[00:48:21] - Venture investing lessons he’s learned from Lauren Gross

[00:50:00] - His first VR project and aspirations for the future of VR

[00:54:50] - The role of religion and spirituality in his business philosophies

[00:59:13] - Why he tries to capitalize on morality as opposed to sin

[01:03:57] - The kindest thing anyone has ever done for him

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Huberman Lab

Podcast Notes * “When it comes to nutrition, quality, quantity, and timing – all these three matter.” – Dr. Satchin Panda * Intermittent fasting really means caloric restriction; time-restricted eating doesn’t necessarily reduce caloric intake but does reduce the time of eating food (for example, 16hrs fasting and 8 hours of eating) * Consistency is a critical component of TRE: our body has an internal timetable that pre-programs molecular aspects of the cells – they want to do certain things at certain times; we can use feeding to tune our cells + Adhere at least 5 days per week; obviously, every day is best but improvements have been observed 5 out of 7 days * A feeding window of 10 or 12 hours is a good place to start (particularly if you exercise), then taper down to 8 hours of feeding if it feels right for you + Be advised, reducing the feeding window too much can have negative side effects, particularly for athletes or very active people * Most studies exclude shift workers because of schedule and known disruption to physical and mental health – even 1-2 nights of being awake when you expect to sleep can take a week to recover

Read the full notes @ podcastnotes.org

In this episode, my guest is Satchin Panda, PhD, professor and the director of the Regulatory Biology Laboratories at the Salk Institute for Biological Studies. We discuss his lab’s discovery that “time-restricted eating” (TRE) aka intermittent fasting, is beneficial effects for metabolic health and longevity. Dr. Panda explains how TRE, and also longer fasts, can positively impact obesity, diabetes, cardiovascular health, age-related chronic diseases, and improve mood and cognitive performance. He also describes how the timing of eating, light exposure and exercise that ~50% of all people engage in, negatively impacts their health and explains how specific simple adjustments to these can positively shift their subjective feelings of health and biomarkers of cardiovascular function, glucose regulation and metabolism. We discuss how our circadian behaviors, which include our patterns of eating, sleeping and socializing, have an enormous impact on our biology, mood and health and how by simply confining our calorie consumption to a semi-regular daily window, can positively impact our physical health, mental health and longevity.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
HVMN: https://hvmn.com/huberman
Eight Sleep: https://eightsleep.com/huberman
Thesis: https://takethesis.com/huberman
Momentous: https://www.livemomentous.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Timestamps
(00:00:00) Dr. Satchin Panda
(00:03:02) Sponsors: HVMN, Eight Sleep, Thesis, Momentous
(00:07:24) Time-Restricted Eating (TRE), Calorie Restriction (CR) & Health
(00:14:38) Mealtimes & Circadian Clock
(00:21:34) Circadian Rhythm, Meal Anticipation, Digestion
(00:25:28) Breaking a Fast, Burning Fat
(00:32:49) Sponsor: AG1 (Athletic Greens)
(00:34:04) CR, Time Restricted Eating, Circadian Rhythm & Longevity
(00:47:20) Gender, Hormones & CR; Relative Energy Deficient in Sports (REDS)
(00:52:40) Physical Activity, Nutrition & Feeding Window
(00:59:04) Nutrition Timing, Quality & Quantity; Low- Carbohydrate Diet
(01:03:00) Caffeine, Nighttime Socialization, Fire, Breakfast
(01:15:07) Sponsor: InsideTracker
(01:16:20) Circadian Rhythm, “Night Owls” & Genetics
(01:26:37) Morning vs. Nighttime Discussions, “Me Time”
(01:30:08) Light Sensitivity & “Night Owls”; Puberty, Melatonin
(01:36:05) Shift Workers, Health & Disease
(01:45:43) Artificial Lights, Young Adults & Sleep, Metabolic Dysfunction
(01:50:59) Firefighters, Sleep & TRE; Cardiovascular Health, Blood Glucose
(02:05:18) Shift Workers & Sleep; Alcohol & Caffeine
(02:09:15) 12- Hour Feeding Window for Adults & Children, Sleep
(02:22:10) Meal Timing
(02:25:20) “Complete Fast”, Longer Fasts, Physical Health & Mental Health
(02:28:12) “Fat Fasting”, Blood Glucose & Insulin
(02:31:57) Fasting, Metformin, Rapamycin & Longevity; Human Applicability?
(02:39:14) Circadian Rhythm & Metabolism
(02:41:36) Ontime Health App, Circadian Clock App
(02:46:17) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Learning Leader Show

Podcast Notes Key Takeaways * Check Out the Learning Leader Show Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Text Hawk to 66866 to become part of "Mindful Monday." Join 10's of thousands of your fellow learning leaders and receive a carefully curated email from me each Monday morning to help you start your week off right...

Full show notes at www.LearningLeader.com

Twitter/IG: @RyanHawk12 https://twitter.com/RyanHawk12

David Lieberman, Ph.D., is a renowned psychotherapist and the author of eleven books, including the New York Times bestsellers Get Anyone to Do Anything and Never Be Lied to Again. He has trained personnel in the U.S.

Ralph Waldo Emerson wrote: “People do not seem to realize that their opinion of the world is also a confession of character.” A person looks at the world as a reflection of themselves. If they see the world as corrupt, they feel on some level that they are corrupt. If they see honest working people, that is frequently how they see themselves.
“How someone treats you is a reflection of their own emotional health and says everything about them and nothing about you.”
Speaking negatively behind someone’s back orients you to look for the negative in others. Wouldn’t we rather spend time with people who seek the greatness in others?
“The less emotionally healthy a person is, the more they denigrate the world to accommodate their own insecurities.”
Knowledge is not power. Knowledge is a tool. How it is wielded makes all of the difference. Real power is the responsible application of knowledge.
Word usage: Let’s take the example of giving a compliment. A woman who believes what she’s saying is more likely to use a personal pronoun. For instance, “I really liked your presentation.” However, a person offering insincere flattery might say, “Nice presentation,” or “Looks like you did a lot of research.” In the second case, she has removed herself from the equation.
The Art of reading the bluff - When a person is bluffing, they are managing others’ impressions to convey the “right” effect and serve a personal agenda. Conversely, the authentic person is not interested in how they come across because they are unconcerned with their image.
- “People who bluff habitually overcompensate, so you can uncover a bluff instantly by noticing how someone tries to appear.”
Relationships: Whenever David speaks to couples, he's always on the lookout when the word we is conspicuously absent from the conversation.
We are attracted to positivity. It reflects humility.
"Humility connects you to the ownership of mistakes."
- Humility can recognize a weakness in self.
The difference between a sociopath and a psychopath:
- A sociopath has no conscious. They are very dangerous.
- A psychopath's wiring is off. They were born that way.
Life and career advice: Find a passion that contributes to the world.
- Don't get too caught up in image or ego.
"You can be anything. you're good at. as long as they're hiring." -- Chris Rock

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * GLP-1 and GIP both started as drugs to control glucose and insulin resistance in people developing or with type 2 diabetes * Studies showed the added benefit of GLP-1 agonists on weight loss but the mechanism is unclear, though they do reduce appetite in some way

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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In this “Ask Me Anything” (AMA) episode, Peter focuses the discussion on two topics getting a lot of attention recently. He first dives deep into GLP-1 agonists, most notably semaglutide and tirzepatide, which originally came to market as diabetes drugs but are now being studied and prescribed for weight loss. He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them. Next, Peter discusses how metformin, another drug originally brought to market for diabetes management, gained popularity as a potential longevity drug even for non-diabetics. Peter gives his take on this possibility and reviews data from a more recent study investigating the question of whether metformin should be used for general “geroprotection.”

If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #45 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.

We discuss:

The hype around semaglutide, tirzepatide, and other GLP-1 agonists for weight loss [2:30];
Overview of GLP-1 agonists and why these drugs are getting so much attention [6:15];
Defining the term “geroprotective” [13:30];
Semaglutide: background, brand names, indications, and more [15:15];
Tirzepatide: background, brand names, indications, and more [19:15];
How semaglutide and tirzepatide compare in their efficacy in terms of weight loss and other metabolic health metrics [23:45];
Data showing sustained weight loss and improved metabolic metrics with after more than a year of using semaglutide and tirzepatide [29:00];
What happens to body weight when a patient discontinues the medication? [34:45];
Noteworthy side effects of GLP-1 agonists and similar classes of drugs [40:45];
Increased resting heart rate and other concerning trends in patients using GLP-1 agonists [45:15];
Changes in body composition (body fat and lean muscle) in patients on GLP-1 agonists [50:45];
Possible reasons for the loss of lean muscle mass and tips for protecting lean mass [59:00];
GLP-1 agonists and thyroid cancer [1:01:30];
Who might be a candidate for GLP-1 agonists? [1:03:45];
The large financial cost of this class of drugs [1:08:30];
Metformin as a geroprotective drug: origin of the idea that metformin could be a longevity agent even for non-diabetic patients [1:11:30];
A 2022 study on metformin sheds more light on the question of whether metformin should be used for “geroprotection” in non-diabetics [1:21:00];
Peter’s current approach with metformin for his patients [1:25:15]; and
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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A16z Podcast

Podcast Notes Key Takeaways * Check Out the a16z Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

With every new technology, some jobs are lost while others are gained. People often focus on the former, but in this episode we chose to highlight the latter – a highly creative role that emerges alongside AI: the prompt engineer.

Until AI can close the loop of its own, each tool still requires a set of prompts. Just like a composer feeds an instrument the notes to play, a prompt engineer feeds an AI a map of what to produce. And if we know anything from music it’s that composing great music takes great skill!

In this episode we explore the emerging importance of prompting with Guy Parsons, the early learnings of how to do it effectively, and where this field might be going.

Will the prompt engineer be more like the highly sought after DevOps engineer, or a proficiency like Excel that you find on every resume? Listen in to hear Guy’s take.

Interested in the prompt competition? Email us at podpitches@a16z.com.

Resources:

DALL-E 2 Prompt Book: https://dallery.gallery/the-dalle-2-prompt-book/

Find Guy on Twitter: https://twitter.com/GuyP

Guy’s combining image experiment: https://twitter.com/GuyP/status/1612880405207580672

Guy’s amorphous prompt experiment: https://twitter.com/GuyP/status/1608475973300948993

Guy’s space duck: https://twitter.com/GuyP/status/1601342688225525761

Prompt base: https://promptbase.com/

Lexica: https://lexica.art/

Topics Covered:

0:00 - Introduction

01:49 - DALL-E 2 Prompt Book

05:29 - Parallel skills

06:51 - 80/20 prompting

10:16 - New ways of prompting

13:44 - Pulling the AI slot machine

18:09 - Comparing models

21:04 - Requested features

26:34 - Learning with AI

27:58 - Practical use cases

32:08 - A top 1% prompt engineer

36:17 - The most popular images

Stay Updated:

Find us on Twitter: https://twitter.com/a16z

Find us on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

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Art of Manliness

Podcast Notes Key Takeaways * If you don’t understand how to train hard, aren’t consistent about training, or have poor nutrition – supplements aren’t going to move the needle * “If people took the amount of time, effort, and money they spent trying to hack their way around hard work and just applied that to hard work – they would get so far. That’s actually the hack, just to do the work.” – Dr. Layne Norton * Timing of protein is not as important as hitting daily targets + 0.8g/kg body weight for maintenance + 1.6-2.6g/kg body weight for building muscle * Even if you are not concerned about training performance and muscle, supplementing with creatine monohydrate may have positive benefits * Stay away from supplements that use the label “proprietary blend” – they’re usually hiding the best ingredients in the smallest portion and don’t want to disclose * If you follow a plant-based diet, you may want to supplement with protein because the protein in plants is bound in fibrous material and is less bioavailable + Soy protein is a complete protein; pea protein lacking so mix it with wheat isolate or other protein for a complete profile

Read the full notes @ podcastnotes.org

In your journey towards becoming stronger, fitter, and healthier, there often comes a point where you wonder if taking some supplements will help your progress along. But what fitness supplements are actually effective and worth investing in?

Here to answer that question is Layne Norton, a powerlifter and doctor of nutritional science who has a passion for debunking health-related myths and promoting evidence-based recommendations. He’s also, full disclosure, the owner of a supplement company himself. But I don’t have any financial connection to Layne’s company and we keep this conversation neutral and high-level. In our conversation, Layne argues that there are three top-tier research-backed supplements to consider — whey protein, creatine, and caffeine — and we unpack how to use each of them for optimal results. We discuss whether plant proteins are sufficient for building muscle, whether it’s true that creatine causes bloating, acne, and hair loss, how to best time your caffeine intake to energize your workouts, and much more. At the end of our conversation, Layne shares some additional supplements that seem promising for enhancing your health and fitness.

Resources Related to the Episode* Layne’s previous appearance on the AoM podcast: Episode #475 — How to Lose Weight, and Keep It Off Forever * Layne’s supplement company: Outwork Nutrition * AoM Article: A Primer On Muscle-Building Supplements — Which Work and Which Don’t? * AoM Article: Creatine — A Primer on Its Benefits and Use * AoM Article: How to Use Caffeine to Optimize Your Workouts * AoM Article: Chugging Your Protein — It’s Whey Easier Than You Think * AoM Podcast #285: The Real Science of Nutrition and Supplements

Connect With Layne Norton* Layne on Instagram * Layne‘s website

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My First Million

Podcast Notes Key Takeaways * You might have to go to some pretty dark places mentally to achieve great things physically * It is very hard to beat the guy who wants to die to win * “I don’t have anything that anyone listening to this show doesn’t have. I promise you.” – Ken Rideout * Ken once made $262,000 in a single day working on Wall Street * He was a functional addict for 10 years while working on Wall Street, and eventually got sober when he started having children * Of all the things that he has achieved, he is most proud of being sober * Ken Rideout used endurance sports to deal with his addiction, and through endurance sports, he discovered his ability to suffer through adversity and the pain of quitting * The only way to deal with adversity is to go through it * The coward and the hero feel the same exact thing; how they behave is where they differ * You find out who you really are when you experience setbacks * Do the little extra things that you know your competition is not doing * You can become the best in the world at something if you do it more than anyone else and devote yourself to it more than anyone else * “I try to be as humble as I can. I know that there are a lot of things that I’m not good at, but suffering is one thing that I know how to do.” – Ken Rideout * Money can alleviate stress, but it can also add stressors that you didn’t even know existed * Ken’s level of activity may make his life a little shorter, but it increases his quality of life to the degree that it is worth it to him * Find something in your life that you are passionate about and that you genuinely enjoy * The harder you work, the luckier you will get

Read the full notes @ podcastnotes.org

Episode 427: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) speak to Ken Rideout (@KenRideout_), one of the world's best masters runners, successful businessmen and entrepreneur. Ken talks about how he overcame addiction, built a lucrative career, forged mental and physical toughness, and where that's going to take him in the years to come.
Want to see more MFM? Subscribe to the MFM YouTube channel here.
SHAAN'S NEW DAILY NEWSLETTER --> shaanpuri.com

Links:
Teddy Atlas Podcast
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.

Show Notes:
(00:23) - Why Ken is blowing up
(12:25) - His finance background
(23:45) - Ken's Struggles with Addiction
(25:40) - How he got into running/media
(31:25) - Who are the toughest people you have met?
(38:20) - How to deal with adversity
(41:50) - Story of Ken talking smack to Lance Armstrong
(44:30) - How does he make money?
(53:35) - Does this level of activity increase longevity?

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Huberman Lab

Podcast Notes Key Takeaways * A rough estimate of hydration needs at rest: consume 8oz of fluid for every hour you are awake for the first 10 hours of your day – this can be consumed as total volume over the course of the day * Follow Galpin’s equation for hydration during exercise: your body weight (in pounds) / 30 = # of ounces to consume every 15 minutes * Deliberate cold exposure sample protocol:2 minutes of deliberate cold exposure/water immersion up to the neck + 30 seconds of deliberate cold exposure with cold shower 5x per week + Potential benefits: increase in catecholamines (benefits mood and well-being), sexual satisfaction (probably from increases in testosterone in men and women), reduction in anxiety, reduction in waist circumference in men, reduction in abdominal fat in men * To reduce nighttime urination frequency: (1) hydrate sufficiently during the day; (2) reduce fluid intake at night; (3)don’t chug water at night if you drink! sip slowly, rate matters * Know how much fluoride is in your tap water! Google your zip code + water analysis – (high fluoride even at 0.5mg/mL can negatively impact thyroid stimulating hormone) * You don’t need to enrich your water but if pH is insufficient or magnesium is low, address it to achieve better and more efficient hydration, reduce inflammation, blood pressure, and other health metrics + Find out the profile of your tape water by googling your zip code + water analysis + You can purchase hydrogen molecular tablets to drop in water which will increase pH

Read the full notes @ podcastnotes.org

In this episode, I discuss our body’s most vital and essential nutrient—water. I explain the structure of water and how it is used by the cells and tissues of our body, how much water we each need to drink and when in order to optimize our mental focus and physical performance; and I include how exercise, humidity, heat, and caffeine affect our hydration needs. I explain how temperature and pH influence water’s physical properties and if there is any scientific basis for drinking so-called “pH water” or “alkalized water” to improve health. I explain how to test your tap water for contaminants (e.g., endocrine disruptors) and the documented problems with fluoride in drinking water. I provide options for filtering drinking water and describe different water types (e.g., reverse osmosis, hydrogen-enriched, electrolyzed reduced, deuterium depleted, etc.). Since the human body is mostly water (55-80% depending on one’s age) and water has essential roles in health, disease and cellular function, everyone ought to benefit from understanding how best to clean our tap water, hydrate effectively and in some cases, adjust the type of water we drink to allow our brain and body to function optimally in regard to health and performance.
For recommended water filters, tests and the full show notes, please visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Thesis: https://takethesis.com/huberman
HVMN: https://hvmn.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Water
(00:03:33) Tool Deliberate Cold Exposure, Immersion & Showers Mood & Fat Loss
(00:15:26) Sponsors: LMNT, Thesis, HVMN, Momentous
(00:19:27) Water: Physical Properties & Chemistry
(00:26:32) Bonds & Water Phases, “Structured Water”
(00:34:07) Body, Cells & Water
(00:36:22) AG1 (Athletic Greens)
(00:37:37) Water as a Solvent, Temperature & pH
(00:41:49) Water Transport in Cells, Aquaporin Channels
(00:49:46) Alkaline/pH Water; Temperature, pH & Water Transport
(00:55:14) Water Cellular Function, Reactive Oxygen Species (ROS) & Antioxidants
(01:01:20) Sponsor: InsideTracker
(01:02:38) Tool: Baseline Hydration
(01:11:35) Tool: Hydration & Exercise, Galpin Equation
(01:15:40) Tool: Hydration, Sauna, Humidity & Sweat; Thirst, Caffeine
(01:19:15) Hydration; Cognitive & Physical Performance
(01:23:53) Tool: Water Filtration; Nighttime Urination
(01:29:35) Tap Water Tests, Disinfection Byproducts (DBPs), Fluoride & Thyroid Health
(01:37:18) Tool: Water Filters
(01:44:18) Tool: Resting Tap Water & Sediment
(01:48:13) Tool: “Hard Water”; Magnesium, Calcium & Cardiovascular Health
(01:53:40) Water Temperature
(01:56:42) Water Types: Distilled, Reverse Osmosis, Hydrogen-Enriched
(02:03:26) Hydrogen-Enriched Water, Magnesium, Optimize Hydration
(02:11:13) Tool: Molecular Hydrogen Tablets, Water pH
(02:14:05) Structured Water
(02:16:39) Tool: Water Pipes, Faucet Filter
(02:19:42) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Twenty Minute VC

Mike Cessario is the Founder and CEO @ Liquid Death, the man hacking the healthy beverage market with the first hilarious water brand. It is working, Liquid Death's latest valuation was over a staggering $700M and Mike has raised over $200M since founding the company from the likes of Science Inc. Away's Jen Rubio, Dollar Shave Club's Michael Dubin, Swedish House Mafia and Tony Hawk to name a few. Prior to founding Liquid Death, Mike was in the advertising industry at a number of dirrect firms including VaynerMedia.

In Today's Episode with Mike Cessario We Discuss: 1.) From Canned Water to $700M Business:

How did rockstars' hydration problems lead to the founding of Liquid Death?
How did growing up with guns and heroine needles around him at school, impact how Mike sees the world today? What is he running from? What is he running towards?
Everyone said, "canned water, that is a stupid idea". What does Mike tell to all entrepreneurs who are told their idea is stupid? How does Mike advise on picking your idea?

2.) How to Build a Truly Great Brand:

What does the term "brand" mean to Mike?
What does he mean when he says, "truly great brand transcends functional value"?
What are the single biggest mistakes Mike sees founders make today on branding?
Why does Mike believe people will always hate your brand, if it is good?
What are the biggest brand mistakes Mike has made with Liquid Death?
What brand does Mike most respect and admire? Why that brand?

3.) Marketing: The Secret to Reaching Millions of People with Little Budget:

How does the Liquid Death team come up with the ideas they have for content? Why does Mike believe the label "storytelling" is kinda BS?
Why does Mike believe people will always hate your marketing? What was Mike's biggest lesson from their Superbowl commercial with kids drinking Liquid Death, looking like beer?
How does Mike decide which channel to prioritise? How has the rise of TikTok and short form video changed their approach to content?
How does Mike approach resource allocation for new pieces of content? Do they spend big on few bits of content or spend little on many and see what works?

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Huberman Lab

Podcast Notes Key Takeaways * Genes and patterns of inheritance shape our lives and who we are * Most people get the concept of epigenetic inheritance wrong – it really means that the environment of the parent somehow changed future children * Bottom line, we need larger studies to understand the extent of epigenetics – it’s also difficult to design because we have to control environmental effects * For memories to pass through generations, there has to be a transformation of the neural circuit into the nucleotide sequences contained in DNA or RNA (more likely) + The transformation of one set of physical points to a translation of points in genetic points needs to take place * True epigenetic effect has been observed in c. elegans: it was shown that the brain can communicate with the next generation using small RNAs and this can change behavior in 3 generations without using any language

Read the full notes @ podcastnotes.org

In this episode, my guest is Oded Rechavi, Ph.D., professor of neurobiology at Tel Aviv University and expert in how genes are inherited, how experiences shape genes and remarkably, how some memories of experiences can be passed via genes to offspring. We discuss his research challenging long-held tenets of genetic inheritance and the relevance of those findings to understanding key biological and psychological processes including metabolism, stress and trauma. He describes the history of the scientific exploration of the “heritability of acquired traits” and how epigenetics and RNA biology can account for some of the passage of certain experience-based memories. He discusses the importance of model organisms in scientific research and describes his work on how stressors and memories can be passed through small RNA molecules to multiple generations of offspring in ways that meaningfully affect their behavior. Nature vs. nurture is a commonly debated theme; Dr. Rechavi’s work represents a fundamental shift in our understanding of that debate, as well as genetic inheritance, brain function and evolution.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
ROKA: https://roka.com/huberman
HVMN: https://hvmn.com/huberman
Eight Sleep: https://eightsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Oded Rechavi
(00:02:08) Sponsors: ROKA, HVMN, Eight Sleep
(00:06:04) DNA, RNA, Protein; Somatic vs. Germ Cells
(00:14:36) Lamarckian Evolution, Inheritance of Acquired Traits
(00:22:54) Paul Kammerer & Toad Morphology
(00:28:52) AG1 (Athletic Greens)
(00:30:06) James McConnell & Memory Transfer
(00:37:31) Weismann Barrier; Epigenetics
(00:45:13) Epigenetic Reprogramming; Imprinted Genes
(00:50:43) Nature vs. Nurture; Epigenetics & Offspring
(00:59:06) Generational Epigenetic Inheritance
(01:09:03) Sponsor: InsideTracker
(01:10:20) Model Organisms, C. elegans
(01:21:50) C. elegans & Inheritance of Acquired Traits, Small RNAs
(01:26:02) RNA Interference, C. elegans & Virus Immunity
(01:34:13) RNA Amplification, Multi-Generational Effects
(01:38:41) Response Duration & Environment
(01:47:50) Generational Memory Transmission, RNA
(01:59:36) Germ Cells & Behavior; Body Cues
(02:04:48) Transmission of Sexual Choice
(02:11:22) Fertility & Human Disease; 3-Parent In Vitro Fertilization (IVF); RNA Testing
(02:17:56) Deliberate Cold Exposure, Learning & Memory
(02:29:26) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Aarthi and Sriram's Good Time Show✓Claim

Podcast Notes Key Takeaways * The recent breakthroughs with ChatGPT break the world into two groups: those who can understand exponential growth, and those that sit around and deny it * AI hallucinations are evidence that we have apparently solved the problem of computer creativity * The real breakthroughs are going to happen when entrepreneurs discard all current assumptions and purely start from scratch * “This may be the single biggest financial explosion in the history of the industry.” – Marc Andreessen * “It may only be the case that new companies can actually do anything interesting in AI.” – Marc Andreessen * Much of the current concern over AI is not about the Skynet doomsday scenario, but about how AI will abide by approved woke-speech * AI is replacing jobs in the opposite order in which people expected it to * We are in the midst of another high-octane Luddism fallacy where people panic and believe new technology is going to replace all the jobs * People always underestimate the degree to which new technology creates new jobs * Virtually every white-collar job that exists today is the result of technological advancement that occurred in the last 300 years or even 50 years * “Our biggest problem for the next decade is not going to be AI having too much effect, it’s going to be AI having too little effect.” – Marc Andreessen * We must accept that the most amazing technological breakthrough of all time – replicating human consciousness – is just going to happen accidentally * Questioning AI sentience reveals more about human values and how humans perceive the world than they reveal about the technical components of a machine * AI science fiction is largely based on the assumption that humans and machines will inevitably go to war with one another, but people are experiencing the exact opposite reaction when interacting with ChatGPT

Read the full notes @ podcastnotes.org

In this episode, the gang gets back together! Marc Andreessen and Steven Sinofsky are back to talk about all things AI. We cover the rise of ChatGPT, Bing's AI powered chat Sydney, AI ethics, sentience, whether AI will take over jobs, the economic impact, AI startups vs tech incumbents, and whether it is time for AI to become sentient. This was an incredibly fun episode! Marc Andreessen is an American entrepreneur, venture capital investor, and software engineer. He is the co-author of Mosaic, the first widely used web browser; co-founder of Netscape; and co-founder and general partner of Silicon Valley venture capital firm Andreessen Horowitz. Steven Jay Sinofsky is a former president of the Windows Division at Microsoft. He was responsible for the development and marketing of Windows, Internet Explorer, and online services such as Outlook.com and SkyDrive.

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Knowledge Project

Podcast Notes Key Takeaways * Check out the Knowledge Project Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

In the third installment in a series of episodes, The Knowledge Project curates essential segments from five guests revolving around one theme: leadership. This episode helps put a unique definition on leadership and examines whether or not good leaders are context-dependent, the differences between a great leader and an average leader, how great leaders should balance feedback, the difference between being right and doing right, a playbook for managing teams, and the importance of radical candor.

The guests on this episode are author Jim Collins (Episode 61, 110), author and leadership expert Jennifer Garvey Berger (Episode 43), co-founder of the Admired Leadership Institute Randall Stutman (Episode 96), the President and COO of Athletic Greens Kat Cole (Episode 117), the former CEO of Ford Alan Mulally (Episode 151), and co-founder of the Conscious Leadership Group Diana Chapman (Episode 130). --

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Overthink ✓ Claim

Podcast Notes Key Takeaways * Check Out the Overthink Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

To be or not to be? That is the question. At the center of Hamlet’s soliloquy is the issue of whether life is worth living. In episode 72 of Overthink, Ellie and David consider this issue with philosopher and existentialism expert Céline Leboeuf. How can we find meaning in our lives when the world seems random and indifferent to our interests? Leboeuf talks about how her personal experience with an existential crisis and her philosophical search for a way out of it led her to consider religious, atheist, and spiritual answers to the question "Why Live?" Ellie and David also consider Camus’ notion of the absurd, and whether life is just a series of blips of suffering with no higher purpose.

Works Discussed

Albert Camus, The Myth of SisyphusWilliam James, “Is Life Worth Living”
Céline Leboeuf, "Why Live? The Three Authors Who Saved Me During an Existential Crisis"
John Jay McDermott “Why Bother: Is Life Worth Living?”
Samuel Scheffer, Death and the AfterlifeLeo Tolstoy, A Confession

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Website | overthinkpodcast.com

Instagram & Twitter | @overthink_pod

Email | Dearoverthink@gmail.com

YouTube | Overthink podcast

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Huberman Lab

Podcast Notes Key Takeaways * Being middle of the road on hydration is fine but even one standard deviation off will induce fatigue, brain fog, GI distress, and more + Every cellular process in the body relies on having enough sodium and magnesium in the system * Foundation for hydration: drink about ½ ounce of water per pound of bodyweight * Replace 125% of fluid lost during exercise + Exercise-related fluid loss varies – for most conditions it’ll be about 1-2 pounds you’ll want to replace * Sip on water, don’t chug! Your system may become diluted when you chug * A large percentage of your hydration should actually come from eating real, whole foods – you shouldn’t feel like you have to smash bottle after bottle of water to stay hydrated + Use WUT system: weight, urine (color and output), and thirst to assess hydration * Unless you are a high-level athlete, hitting total daily macronutrient goals (especially protein) matters more than the timing of intake * Go into workouts hydrated to avoid negative consequences; consume about 1/2 ounce of water per pound of bodyweight * For hydration during exercise, use Galpin’s equation: every 15 minutes, consume X ounces per pound of body weight / 30 * Unless you are supplementing for foundational support (vitamins, minerals, foundational compounds, adaptogens, probiotics, prebiotics), focus on single-ingredient formulated supplements for the most power and control overdose + Be choosy with blends: different ingredients also have varying costs so you’re likely going to get more of the least expensive ingredients and less of the thing you actually want * “The end goal anytime I coach somebody is to get them into a physiological state where they require no or close to no supplementation. That’s the target.” – Dr. Andy Galpin + Supplements can cover the pain point signal that might otherwise force you to take behavioral action * Adjustments to make for a better sleep environment: keep pets out of the bedroom (at minimum off the bed), check light and temperature, wash your sheets, explore allergens and dander in the room, elevate head if you have acid reflux, only use your bed for sex and sleep * Don’t turn to anti-inflammatory supplements or ice baths in the hours or day after training – you want the inflammatory response to generate adaptation + Instead, consider: omega-3, glutamine, magnesium, calcium (if concerned about bone injury), vitamin D, and tart cherry juice for persistent soreness

Read the full notes @ podcastnotes.org

In this episode 6 of a 6-part series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton, he explains optimal nutrition, hydration and supplementation to achieve your fitness goals. We cover macronutrient guidelines, when to eat relative to training and training fasted versus fed. Dr. Galpin describes proper hydration for before and during exercise, how dehydration and/or low electrolyte concentrations impede physical and mental performance. He discusses what supplements work best for fitness and performance, how to decide which to take, if any, and when to take them. He also shares high-impact, lower-cost supplements and nutrition recommendations to benefit performance, recovery, and sleep. This episode also includes an audience Q&A. Overall, it is an in-depth but clear discussion of nutrition strategies and supplements that can help anyone improve their level of fitness physical and mental performance.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
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Timestamps
(00:00:00) Nutrition & Supplementation
(00:05:16) Creatine Supplementation, Muscle & Cognitive Function, Loading Phase
(00:16:51) Sponsors: Momentous, Levels, LMNT
(00:20:31) Dehydration, Overhydration, Night Urination
(00:35:37) Tool: Hydration, Caffeine & Electrolytes
(00:41:22) Tool: Sweating, Salt & Performance
(00:48:57) AG1 (Athletic Greens)
(00:49:49) Galpin Equation for Hydration & Exercise, Focus
(00:55:28) Tool: 5 Steps to Optimize Hydration, Sipping Water, W.U.T. Status, Salt
(01:10:58) Electrolytes, Carbohydrates & Exercise
(01:15:44) Sponsor: InsideTracker
(01:16:47) Training Fasted versus Fed, Caffeine, Carbohydrate Timing
(01:25:13) Caffeine & Endurance
(01:31:20) Citrulline, Beet Root Juice & Performance; Alpha-GPC & Focus, Nootropics
(01:35:43) Rhodiola, Cortisol & Fatigue
(01:39:55) Tool: Supplement Formulations
(01:47:31) Supplements, Dependency & Root Cause; Foundational Behaviors
(01:57:44) Acute vs. Chronic Effects, Supplements & Gut Microbiome
(02:02:33) Tool: Sleep Environment, Absolute Rest
(02:11:03) Tools: Sleep & Disturbances, Inositol
(02:20:03) Tool: “Fitness Fatigue” Model, Taper, Anti-Inflammatory Supplements
(02:26:33) Exercise Recovery: Curcumin, Omega 3s, Glutamine, Nutrition, Vitamins
(02:39:27) Intermittent Fasting, Training & Keto Diets; GABA
(02:43:39) Carbohydrate Loading; Amino Acid Supplements; “Anabolic Window”
(02:47:23) Garlic; Tart Cherry Extract; Examine.com
(02:51:50) Fitness Testing, Training Programs; Exercise Recovery
(03:04:13) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Moonshots and Mindsets with Peter Diamandis✓Claim

Podcast Notes Key Takeaways * Building something meaningful will be a decade-long process; you might as well build something that is going to meaningfully make people’s lives better * The power law of returns describes how the minority of companies you invest in will deliver the majority of your returns * If you are a technical founder, the number one mistake you can make when approaching VCs is to only talk about the technology and not the customer * Do not create technologies and then look for problems that they can solve; identify problems and create technologies to solve them * Understand that many of the letters and names in venture capital are made up; do not get too stuck on any of the letters or names * Understand what matters to the audience that you are presenting to * It is better to make micro-pivots that add up to a larger pivot in aggregate than having to make a single massive pivot at once * The desire to grow personally and contribute to the world will endlessly fuel a person * Successful founders are unwilling to accept “no” for their long-term mission but are willing to make micro-adjustments along the way when presented with new information * Great entrepreneurs fail constantly, and their failures become learnings and fuel rather than fatal injuries * Equating failures with growth is a mindset that breeds long-term success * Consider the scope of the problem you are trying to solve if you are a first-time founder + Consider attacking a smaller niche within an area that interests you if you are a first-time founder

Read the full notes @ podcastnotes.org

In this episode, Dakin and Peter discuss tips for new entrepreneurs, how to build a successful company and the power of venture capital for the economy.

You will learn about:

04:37 | The story of Prime Movers Lab
22:25 | The 'do's & don'ts' for new entrepreneurs.
35:47 | Ambitious Vs. Conservative: creating balance for your company.

Dakin Sloss is a venture capitalist, founder, entrepreneur, and philanthropist. He is the founder and General Partner of Prime Movers Lab, a VC startup that’s become the world’s leading partner in breakthrough scientific startups.

Learn more about Prime Movers Lab.

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * The life that we experience today is not the life that our primate DNA is used to experiencing; civilization happened quickly, and brains changed slowly * Leadership is the ability to move something in a direction that the cultural forces are not already taking things * “More technology means better good times, but it also means badder bad times. And the scary thing is, if the good and bad keep exponentially growing, it doesn’t matter how great the good times become. If the bad gets to a certain level of bad, it’s all over for us.” – Tim Urban * Ideologies quickly become religions to their followers, at which point the solutions proposed by such ideologies can no longer be challenged * It is optimal to create a culture where no idea is sacred so each idea can be properly scrutinized * How you arrived at what you think is more important than what you think * There is social pressure to laugh off any emerging conspiracy theory that is being considered by the other team * An echo chamber is a collaborative culture of low-rung thinking based on a sacred set of ideas that cannot be challenged by anyone in the echo chamber * Politics pulls our psyches down to the primitive mind because politics was life or death for the 10,000 years that we evolved through human history * A lowercase “l” liberal culture must develop an immune system that stands up to people that want to exclusively play power games * The media is not penalized for lying; corporate media journalists are incentivized to lie because they are rewarded with clicks and not held accountable by their team for lying * The ideology of the social justice fundamentalist mob wants to tear apart the delicate workings of liberal democracy and shred the critical lines of trust * Threats to the inner workings of liberal democracy affect everything else that is built on top of it * Awareness without courage does very little * Criticism culture attacks the idea while cancel culture attacks the person * Many colleges are telling their students that there is a right set of views, mainly views based on woke ideology, and anyone who opposes this set of ideas is bad * The future is going to be weird and different; progress over the next several decades will not look like progress over the previous decades, because it never does

Read the full notes @ podcastnotes.org

Tim Urban is the author of the blog Wait But Why and a new book What’s Our Problem?: A Self-Help Book for Societies. Please support this podcast by checking out our sponsors: – House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit – Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil EPISODE LINKS: Tim’s new book: https://waitbutwhy.com/whatsourproblem Tim’s Twitter: https://twitter.com/waitbutwhy Tim’s Website: https://waitbutwhy.com Tim’s Instagram: https://instagram.com/timurban Tim’s TED talk: https://www.youtube.com/watch?v=Rk5C149J9C0 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes:

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Huberman Lab

Podcast Notes Key Takeaways * Breathing is obviously essential to life but how we breathe is important for the quality of life – for example, you can leverage breathing to improve mood, get rid of cramps, sleep better, increase alertness or calmness * Breathing is a unique feature because it is within our control to direct the brain’s excitability through breathing by shifting the duration in inhales/exhales and how long we hold our breath + The more you inhale longer than exhale (preferably through the nose), the more your brain is in a focused mode of accessing and retrieving information * Physiologic sigh practiced for 5 minutes per day over about a month can have the same or better effects on relaxation, reduced stress, lower resting heart rate, and improved mood when compared to meditation + Physiologic/cyclic sigh – 2 inhales through the nose (one big, one smaller) then 1 long exhale through the mouth until lungs empty x 5 minutes + Even just one physiologic sigh is the fastest way to bring about calm in real-time * Test your current carbon dioxide offload with the carbon dioxide tolerance test; based on the results, use various duration of box breathing to improve mechanical control over breathing and reduce resting respiratory rate * Whenever possible, breathe through your mouth instead of your nose – you don’t want to default to mouth breathing as your mode of breath for many reasons from efficiency to the aesthetic structure of the jaw

Read the full notes @ podcastnotes.org

In this episode, I explain the biology of breathing (respiration), how it delivers oxygen and carbon dioxide to the cells and tissues of the body and how is best to breathe—nose versus mouth, fast versus slow, deliberately versus reflexively, etc., depending on your health and performance needs. I discuss the positive benefits of breathing properly for mood, to reduce psychological and physiological stress, to halt sleep apnea, and improve facial aesthetics and immune system function. I also compare what is known about the effects and effectiveness of different breathing techniques, including physiological sighs, box breathing and cyclic hyperventilation, “Wim Hof Method,” Prānāyāma yogic breathing and more. I also describe how to breath to optimize learning, memory and reaction time and I explain breathing at high altitudes, why “overbreathing” is bad, and how to breathe specifically to relieve cramps and hiccups. Breathwork practices are zero-cost and require minimal time yet provide a unique and powerful avenue to improve overall quality of life that is grounded in clear physiology. Anyone interesting in improving their mental and physical health or performance in any endeavor ought to benefit from the information and tools in this episode.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
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Timestamps
(00:00:00) Breathing
(00:05:41) Sponsors: HVMN, Helix Sleep, WHOOP
(00:09:36) Respiration, Oxygen & Carbon Dioxide
(00:18:18) Breathing Mechanics
(00:30:08) AG1 (Athletic Greens)
(00:31:23) Chemistry of Breathing, Hyperventilation
(00:40:35) High Altitudes, Oxygen & Breathing
(00:47:16) Tool: Sleep Apnea, Nasal Breathing
(00:51:50) Brain Centers & Breathing Rhythm
(00:57:23) Brain, Hyperventilation & “Over-breathing”
(01:03:53) What is Healthy Breathing?
(01:08:26) InsideTracker
(01:09:44) Tool: Train Healthy Breathing, Carbon Dioxide Tolerance Test & Box Breathing
(01:22:39) Tool: Breathwork & Stress Reduction; Cyclic Sighing
(01:33:56) Tool: Physiological Sighing & Exercise Side Cramp
(01:39:16) Breathing & Heart Rate Variability
(01:46:21) Tool: How to Stop Hiccups
(01:51:17) Tool: Stress Management & Cyclic Hyperventilation, “Wim Hof Method”
(01:57:11) Deliberate Cold Exposure & Breathing
(01:59:54) Tool: Inhales & Learning; Exhales & Movement
(02:09:15) Mouth vs. Nasal Breathing, Aesthetics
(02:16:19) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Social Media, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Founders✓Claim

Podcast Notes Key Takeaways * Young Bill Gates was like Genghis Khan in a Mr. Rogers costume * Everything he did, he did to the max * Gates’ first interaction with a computer was at Lakeside School, a private school in Seattle where he also met Paul Allen, with whom he co-founded Microsoft with * Bill Gates became obsessed with computers at a young age to the point where his parents banned his usage of them * “You want to maneuver yourself into doing something in which you have an intense interest.” – Charlie Munger * Gates knew that he wanted to be wealthy from an early age; he spoke about his future success and wealth as if it were predetermined * Gates was one of the best math students at Harvard, but he was not the best, which to him, meant he could never be a mathematician * Bill Gates dropped out of Harvard after much convincing from Paul Allen to start what eventually became Microsoft * Gates was financially conservative: Microsoft got from founding to IPO without having to take money from venture capital * Despite Gates being a multi-billionaire and Microsoft being the undeniable leader of its category, Bill Gates still wanted to destroy the competition * Gates knew where he was weak and was willing to listen to others * Apple was just Steve Jobs with 10,000 lives; the founder’s personality is going to be embedded into the company, which was also true for Bill Gates and Jeff Bezos with their respective companies * Bill Gates was intolerant of distractions; he believed “focus” was the key element to success

Read the full notes @ podcastnotes.org

What I learned from rereading Hard Drive: Bill Gates and the Making of the Microsoft Empire by James Wallace and Jim Erickson.

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[4:00] Gates read the encyclopedia from beginning to end when he was only seven or eight years old.

[4:00] Gates had an obsessive personality and a compulsive need to be the best.

[5:00] Everything Bill did, he did to the max. What he did always went well, well beyond everyone else.

[6:00] You want to maneuver yourself into doing something in which you have an intense interest. — Poor Charlie's Almanack: The Wit and Wisdom of Charles T. Munger.

[7:00] Gates devoured everything he could get his hands on concerning computers and how to communicate with them, often teaching himself as he went.

[9:00] A young man with no money and tons of enthusiasm. — The Dream of Solomeo: My Life and the Idea of Humanistic Capitalism by Brunello Cucinelli. (Founders #289)

[10:00] He consumed biographies to understand how the great figures of history thought.

[11:00] The idea that some people were super successful was interesting. What did they know? What did they do? What drove those kinds of successes?

[12:00] Idea Man: A Memoir by the Cofounder of Microsoft by Paul Allen. (Founders #44)

[13:00] “I’m going to make my first million by the time I'm 25.” It was not said as a boast, or even a prediction. He talked about the future as if his success was predestined.

[15:00] Gates and Allen were convinced the computer industry was about to reach critical mass, and when it exploded it would usher in a technological revolution of astounding magnitude. They were on the threshold of one of those moments when history held its breath... and jumped, as it had done with the development of the car and the airplane. They could either lead the revolution or be swept along by it.

[17:00] Bill had a monomaniacal quality. He would focus on something and really stick with it. He had a determination to master whatever it was he was doing. Bill was deciding where he was going to put his energy and to hell with what anyone else thought.

[18:00] Don’t do anything that someone else can do. — Edwin Land

[21:00] You've got to remember that in those days, the idea that you could own a computer, your own computer, was about as wild as the idea today of owning your own nuclear submarine. It was beyond comprehension.

[23:00] There would be no unnecessary overhead or extravagant spending habits with Microsoft.

[25:00] “Pertec kept telling me I was being unreasonable and they could deal with this guy [Gates]. It was like Roosevelt telling Churchill that he could deal with Stalin.

[27:00] Four years in and Microsoft had only 11 employees.

[28:00] Gates sustained Microsoft through tireless salesmanship. For several years he alone made the cold calls and haggled, cajoled, browbeat, and harangued the hardware makers of the emerging personal computer industry, convincing them to buy Microsoft's services and products. He was the best kind of salesman there is: he knew the product, and he believed in it. Moreover, he approached every client with the zealotry of a true believer.

[29:00] When we got up to 30 employees, it was still just me, a secretary, and 28 programmers. I wrote all the checks, answered the mail, took the phone calls.

[31:00] This might be Bill’s most important decision ever: IBM had talked to Gates about a fixed price for an unlimited number of copies of the software Microsoft licensed to IBM. The longer Gates thought about this proposal the more he became convinced it was bad business. Gates had decided to insist on a royalty arrangement with IBM.

[34:00] You have to be uncompromised in your level of commitment to whatever you are doing, or it can disappear as fast as it appeared.

Look around, just about any person or entity achieving at a high level has the same focus. The morning after Tiger Woods rallied to beat Phil Mickelson at the Ford Championship in 2005, he was in the gym by 6:30 to work out. No lights. No cameras. No glitz or glamour. Uncompromised.

— Driven From Within by Michael Jordan and Mark Vancil. (Founders #213)

[36:00] Overdrive: Bill Gates and the Race to Control Cyberspace by James Wallace. (Founders #174)

[42:00] You can drive great people by making the speed of decision making really slow. Why would great people stay in an organization where they can't get things done? They look around after a while, and they're, like, "Look, I love the mission, but I can't get my job done because our speed of decision making is too slow."

—Invent and Wander: The Collected Writings of Jeff Bezos (Founders #155)

[43:00] Alexander the Great: The Brief Life and Towering Exploits of History's Greatest Conqueror--As Told By His Original Biographers by Arrian, Plutarch, and Quintus Curtius Rufus. (Founders #232)

[44:00] Gates was intolerant of distractions.

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Be like Gareth. Buy a book: All the books featured on Founders Podcast

Invent and Wander: The Collected Writings of Jeff Bezos, With an Introduction by Walter Isaacson

Poor Charlie's Almanack: The Wit and Wisdom of Charles T. Munger, Expanded Third Edition

Hard Drive: Bill Gates and the Making of the Microsoft Empire

Alexander the Great: The Brief Life and Towering Exploits of History's Greatest Conqueror--As Told By His Original Biographers

Overdrive: Bill Gates and the Race to Control Cyberspace

Idea Man: A Memoir by the Cofounder of Microsoft

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * The fentanyl crisis is a fallout of the opioid epidemic and has since taken it to an entirely new level * The DEA started to notice an uptick in pain drugs starting in 2010; around the same time that the pain management doctors started recklessly prescribing oxycodone, Vicodin, and Percocets, according to Anthony Hipolito * A person dies of an accidental overdose every five minutes in the United States, mostly from fentanyl * Anthony Hipolito estimates that two-thirds of accidental overdoses are caused by fentanyl + There are poisonings: people are taking a drug (for whatever reason) and do not know that fentanyl has been mixed into what they believe to be taking * Toxicology reports show street doses of fentanyl can be as high as 100x the lethal dose * A decade ago, the most likely causes of death under the age of 40 were car accidents and suicides, but now accidental overdoses rank number one by orders of magnitude * The cartels are making what the DEA calls “rainbow fentanyl”, which are drugs containing fentanyl designed to look like candy * The precursors to fentanyl are mostly shipped from China to Mexico, then the Mexican cartels synthetically manufacture the pure fentanyl before smuggling it across the border in the United States * Border patrol intercepts about 5-10% of the narcotics that make it across the border * America’s youth mostly discover and come to possess fentanyl through social media * Every illicit recreational drug has a chance of being laced with fentanyl, including Adderall and marijuana + The cartels and dealers are putting it into everything to make their drugs stronger and more addictive

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Anthony Hipolito is a sheriff’s deputy in Hays County, Texas with over 24 years of experience in law enforcement. In this episode, Anthony discusses his work to spread awareness about illicit fentanyl use and the drastic increase in accidental overdoses, especially in young people. Anthony explains the deadly nature of fentanyl, including how many counterfeit drugs are now being laced with deadly doses of fentanyl. He breaks down how fentanyl is being brought to the US and how younger and younger kids are being targeted. Additionally, Anthony discusses his goal of spreading awareness to our communities and provides important advice for what parents can do.

We discuss:

Anthony’s life of service in law enforcement [5:30];
Fentanyl: medical use, recreational use, and the recent rise in prevalence [8:30];
The story of a teenager dying from an accidental overdose of fentanyl [16:30];
The scope of deaths being caused by accidental overdoses (the majority of which are from fentanyl) [23:00];
How young kids are being targeted, and how fentanyl makes it across our borders and gets distributed [28:30];
What happens to a person when they overdose [35:30];
Whether laws around drug possession are helping or hurting, and the need to focus on helping people that feel the need to take these counterfeit drugs [37:00];
How fentanyl is being added to all kinds of drugs that you wouldn’t expect [42:45];
What can we do as parents? [47:15];
Narcan: a treatment for opioid overdoses [50:15];
Importance of awareness, having conversations with kids early in life, and other key takeaways for parents [56:30]; and
More.

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Modern Wisdom

Podcast Notes Key Takeaways * Check out the Modern Wisdom Podcast Episode Page

Read the full notes @ podcastnotes.org

Richard Shotton is a behavioural scientist, Founder of Astroten and an author.

This might not be news to you, but the human brain isn't designed to be rational. There are cheat codes to get the brain to believe strange things, do strange things and change in ways you might not anticipate. Richard has one of the best insights into this world of mental models, psychology, consumer behaviour, principles for advertising and social change.

Expect to learn the marketing secret about behaviour change that everyone forgets about, how to make habit formation absolutely seamless, why IKEA is so successful even though they don't make your furniture, a hack that any advertising campaign can use to make it stick in people's minds, how to fix the problem of choice paralysis and much more...

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Extra Stuff:

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Get in touch.

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Email: https://chriswillx.com/contact/

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Huberman Lab

Podcast Notes Key Takeaways * Don’t underestimate recovery – it’s where the real progress and results emerge * Delayed onset muscle soreness (sets in 24-48 hours after exercise) cascade: the swelling response triggers the neural response which then triggers the pain response * You need a high peak for adaptation to occur but also need an extremely sharp recovery for change to take place * You don’t need to combine every single recovery strategy, here are tools to choose from: cold plunge, massage, breathwork, slow-paced music after exercise + Recover tools everyone should use: light movement, sleep * Avoid taking cortisol-reducing supplements prophylactically without knowing your cortisol is high – cortisol regulation needs to be very strategic because you want natural fluctuations throughout the day and with exercise + The key is understanding how quickly you return to the baseline * Heart rate variability (HRV) is a better marker of recovery than resting heart rate but only compare to yourself and not others – measure under the same circumstances every day (ideally in the morning), and take consistently for a month to understand trends before you use as recovery indicator or worry about changes + Don’t stress about daily changes, track percent derivation from norm * If you workout but never feel sore or need outside stimulus to get going, you’re selling yourself short – you want to get good at recovery so you build resilience and the damage lessens * Don’t compare your numbers to others or panic at every change in metric you see: go based on what is normal for you and what normal variations for you and your situation are – make changes when you deviate 4-6 days or more + Changes might be to stress management, nutrition, hydration, sleep, and training volume, or you may need to reassess the program

Read the full notes @ podcastnotes.org

In this episode 5 of a 6-part special series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton, he explains how to optimize post-training recovery and how to avoid overtraining in order to better achieve your fitness and exercise goals. He explains the cellular mechanisms of muscle soreness and pain, why adequate recovery is essential for all physical adaptations, and how to enhance recovery using breathwork, thermal, movement, and pressure-based techniques. He describes how overtraining impedes exercise progress and how to assess if you are overreaching or overtraining, by using specific biomarkers and indicators. Like other performance metrics, recovery is a skill that can and should be trained, and that can be learned. This episode provides an actionable toolkit for how to monitor and improve your exercise recovery abilities, which will improve your overall mental and physical health.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Eight Sleep: https://eightsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Recovery
(00:04:17) Exercise & Delayed Muscle Soreness, Pain
(00:11:35) Muscle Spindles, Reduce Soreness
(00:18:56) Exercise, Homeostasis & Hormesis; Blood Test & Fitness Level
(00:30:20) Recovery Timescales, Adaptation & Optimization
(00:35:10) Adaptation & Biomarkers Levels
(00:40:36) 4 Recovery Levels, Enhance Recovery
(00:47:28) AG1 (Athletic Greens)
(00:48:19) Overreaching vs. Overtraining
(00:52:53) Tool: Acute Overload & Recovery, Breathwork
(01:03:39) Tool: Alleviate Acute Soreness, Compression Clothing
(01:08:27) Tool: Acute Soreness, Massage, Temperature
(01:14:21) Cold & Heat Contrast, Cold Shower vs. Immersion, Sauna & Fertility
(01:20:44) InsideTracker
(01:21:46) Combine Recovery Techniques
(01:24:34) Monitoring for Overreaching & Overtraining
(01:31:33) Overreaching/Overtraining, Performance & Physiology, Sleep
(01:45:41) Overreaching/Overtraining, Biomarkers, Cortisol
(01:50:45) Cortisol, Daily Levels & Performance; Rhodiola Supplementation
(02:01:25) Carbohydrates, Cortisol & Sleep
(02:05:05) Tool: Stress Biomarkers, Heart Rate Variability (HRV)
(02:15:07) Tool: “Acute State Shifters”, Stimulants, Dopamine Stacking, Phones
(02:25:04) Mirrors & Resistance Training
(02:29:01) Tool: “Chronic State Shifters”
(02:32:43) Training Recovery & Resilience; Bowling Alley Analogy
(02:39:45) Trigger Adaptations & Stress Recovery
(02:42:41) Tool: Measure Recovery; Blood Biomarkers
(02:50:06) Libido & Sex Hormones, Supplementation Caution
(03:00:08) Tools: No-/Low-Cost Recovery Measurements
(03:03:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Honestly with Bari Weiss ✓ Claim

Podcast Notes Key Takeaways * About two-thirds of fourth graders are not proficient readers * In the 1960s, an education theory known as “Whole Language” shifted reading instruction toward understanding the meaning of words instead of focusing on phonics and how words work * Two educational theorists Irene Fountas and Gay Su Pinnell became champions of the Whole Language theory and greatly contributed to its widespread adoption throughout the 1970s and 1980s, despite the theory being disproved by cognitive scientists many years before their rise * However, around the same time, new research was released on how our brains actually read + It showed that skilled readers are really good at the letters and sounds component of reading, which was the part that was being discarded in schools * Skilled readers link the spelling, the meaning, and the pronunciation of words instantly; this is the hallmark of being a good reader * If the spelling-meaning-pronunciation connection is strong enough, then readers can focus on the meaning of the text without exerting much effort on the sounds of the words * Trying to predict the next word is exactly how struggling readers read, and that is how our kids are being taught in school * In many cases, teachers are not taught much of anything on how to best teach reading to their students * The “aha moment” for many teachers is when they see their own kid struggling to read * Poverty does play a role in this educational shortcoming, but it is more of an instructional issue * It is possible that there has been an over- or misdiagnosis of dyslexia when in reality, the core issue is reading instruction * Teachers want to get this right; they just need the proper training, guidance, and tools

Read the full notes @ podcastnotes.org

For many parents, the last few years have been eye-opening, as they saw the education system in America crumble under the weight of the pandemic. School closures that went on far too long, ineffective zoom school for kids as young as kindergarten, and other stringent policies that we’re still just beginning to understand the devastating effects of. But like many things during the pandemic, COVID didn’t necessarily cause these structural breakdowns as much as it exposed just how broken the system was to begin with.

Nowhere is that more clear than in our episode today about why 65% of American fourth grade kids can barely read. And about how during the pandemic, parents, for the first time, came face to face with just how bad and ineffective the reading instruction in their kids’ classrooms is and started asking questions about why.

That is the subject of Emily Hanford's new podcast from American Public Media, Sold a Story, where she investigates the influential education authors who have promoted a flawed idea and a failed method for teaching reading to American kids. It’s an expose of how educators across the country came to believe in something that isn’t true and are now reckoning with the consequences – children harmed, money wasted, an education system upended.

Today, guest host Katie Herzog talks to Emily about her groundbreaking reporting and what we can do to make things right.
Learn more about your ad choices. Visit megaphone.fm/adchoices

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The Network State Podcast✓Claim

Podcast Notes Key Takeaways * Check out the Network State Podcast Episode Page

Read the full notes @ podcastnotes.org

Tobi Lütke (Shopify Founder & CEO), Kaz Nejatian (Shopify COO), and Balaji review how Shopify rose from tiny startup to $180B+ global economy, with an annual GMV on par with the GDP of New Zealand. In the process they touch on Hayek, the Hanseatic League, merchant cavemen, the history of the corporation, and the optimal level of platform decentralization.

OUTLINE
00:00 - Introduction
02:39 - Shopify has the scale of a small country
08:49 - Lifestyle businesses take up your whole life
20:52 - SMBs can be harder than startups
27:13 - Shopify could invest in its merchants
32:23 - Shopify's economy is on par with Greece or New Zealand
38:40 - Money, time, risk, attention
39:55 - Is all retail a form of arbitrage?
47:14 - The history of the corporation informs the development of smart contracts
56:57 - Founders start as lead engineer, end up as chief psychiatrist
1:00:27 - Shopify is not just technology but community
1:06:26 - The concept of computational context
1:14:34 - Shopify as a dashboard for the global economy
1:22:48 - Atoms are so much more complex than bits
1:28:41 - Balancing centralized vs decentralized at Shopify
1:43:26 - If they could start a new country, what would Tobi and Kaz build?
2:03:28 - Kaz on working at Shopify
2:04:31 - Tobi's parting thoughts

LINKS
1) 100 true fans: kk.org/thetechnium/1000-true-fans/
2) Gobekli Tepe: smithsonianmag.com/history/gobekli-tepe-the-worlds-first-temple-83613665
3) Shopify active merchant: github.com/activemerchant/active_merchant
4) Fall of Civilizations: youtube.com/@FallofCivilizations
5) Founding vs Inheriting: thenetworkstate.com/founding-vs-inheriting
6) Shopify careers: shopify.com/careers

VIDEO
YouTube: youtube.com/@thenetworkstatepodcast

CREDITS
Editing: twitter.com/DholakiaJaydeep
Images: twitter.com/DholakiaJaydeep

SOCIAL
twitter.com/tobi
twitter.com/CanadaKaz
twitter.com/balajis
thenetworkstate.com

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Econtalk

Podcast Notes Key Takeaways * The way that peer review actually works is not how most people think it does * Peer review is a relatively new thing in the history of science that has not yet stood the test of time * Many papers are not rejected because they are untrue, but because they are considered unworthy or not interesting enough to be published in the given scientific journal * Letterheads at the top of papers do not mean much to the scientists that just want to use the information contained in the paper; a significant portion of the peer review process is status games * The referees do not even look at the data or the analysis of the paper most of the time; checking the results of the paper is virtually never done * The primary misconception of the peer review process: people assume that the paper is being checked for accuracy when it is submitted when in reality it is being evaluated for how interesting the findings are * Most of the papers that are published will never be cited by anybody * The peer review process costs 15,000 person-years, per year in time spent * Fraudulent studies are typically caught after the paper has been published and not during the review stage of the peer review process * If a system claims to be doing something that it does not actually do, then the people that rely on the said system are worse off because they have been misled into trusting something that they should not have * We are not at the end of science; humanity will continue to progress beyond our lifetimes and we will look ignorant very soon * You can imagine an alternative way of doing something when you understand that the current way that it is done is not how it has always been done * We do not gain much from preventing the publication of low-quality work; however, we do lose a lot from preventing the publication of very high-quality work * The truth tends to win out in the long term, so we should strive to increase the variance of the work that is conducted * We need the freedom to say the things that we believe to be true

Read the full notes @ podcastnotes.org

Psychologist Adam Mastroianni says peer review has failed. Papers with major errors make it through the process. The ones without errors often fail to replicate. One approach to improve the process is better incentives. But Mastroianni argues that peer review isn't fixable. It's a failed experiment. Listen as he makes the case to EconTalk host Russ Roberts for a new approach to science and academic research.

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Huberman Lab

Podcast Notes Key Takeaways * Even if you don’t have a specific goal (e.g., marathon, competition), having a training plan is always more effective than not having a plan – you’ll achieve more results in the same amount of time (or less) * Work within the constraints of the non-negotiables in your life (e.g., family, work, time, etc.) + Imagine everything in your life falls into one of four buckets: business, relationships, fitness, or recovery – distribute 10 total points across the four areas and spend some time critically analyzing whether you are allocating energy in the right places and set goals accordingly * Before you even worry about exercise selection: think about where you want to go, how you’re going to get there, and restrictions based on the reality of life, lastly select exercises and balance across the week * Exercise choice: select patterns you can execute, balance muscle patterns and movement joints, specifically target goal muscles or movements, and consider progression strategy * Identify high and low friction training days: bookend the day you can anticipate having your best/most flexible/highest energy day and worst/most exhausting/shortest on time day and plan accordingly + Choose harder workouts on lighter days and easier workouts when you know you’ll be tired and/or short on time * Approaching progressive overload: increase load or intensity for 6 weeks then take a de-load week– this should leave you progressing well, without burnout, and avoiding injury * Chaos management: outline what you want to do then take a day to think about it and make sure you have addressed areas of potential failure or reflection – set yourself up for success * If you find yourself wanting to change your workout too frequently, stop and reassess where you are – are you getting lazy? Are you tired today? – listen to your body and stay within the plan or it’ll be difficult to progressively overload if you train on the fly regularly + If there are too many days you want to go harder, make sure it’s for the right reasons (i.e., not just vanity) and it’s not impacting recovery + If you want to have fun working out with someone to bond, have a rule not to change your program more than 3 days

Read the full notes @ podcastnotes.org

In episode 4 of a 6-part series, Andy Galpin, PhD, explains how to design an effective training program for fitness, health and longevity through a 10-step approach. He covers goal setting, exercise selection, balancing, recovery periods and real-world challenges. He provides a year-long training example that considers sleep, sunlight and social connection. The program is modifiable for personal fitness goals and experience.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Eight Sleep: https://eightsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Optimal Fitness Programming
(00:07:19) Sponsors: Momentous, Eight Sleep
(00:09:53) #1: Plan Fitness Goals, S.M.A.R.T. Goals
(00:19:52) Intermediate Goals, Dopamine, Identify Your “Defender”, Goal Timing
(00:26:25) Multiple Goals, Synergistic Goals, Interference Effects
(00:36:13) AG1 (Athletic Greens)
(00:37:060 Physical Goal “Bins”, Specificity
(00:48:02) Tool: #2: Identify Your “Defender”, Quadrant System, “Drop Everything and…”
(01:04:330 InsideTracker
(01:05:35) #3: Goal Timeframe & Life Events; #4: Weekly Training Frequency
(01:10:33) #5: Exercise Selection, Progression
(01:18:200 #6: Exercise Order, Identify Friction
(01:29:20) Exercise Timing & Sleep, Down Regulation, Caffeine
(01:36:24) #7: Intensity, #8: Volume, Progressive Overload, “Deloading”
(01:43:59) #9: Rest Intervals, #10: “Chaos Management”
(01:49:06) Fitness, Health & Longevity Goals, Proprioception & Non-Structured Exercise
(01:53:41) Tool: Year-Long Program Example for Overall Fitness
(02:07:58) Tool: Overall Fitness Template by Quarter, Matching Goals & Seasons
(02:25:49) Training & Life Challenges: Sleep, Illness
(02:32:10) Tool: Program Flexibility, 3-Day Weekly Training Program
(02:37:12) Physical Activity vs. Exercise
(02:40:12) Tool:4-Day Weekly Training Program, Muscular Endurance
(02:51:15) Tool: 5/6-Day Weekly Training Program, Recovery
(02:54:06) Program Modification, Balancing Joy
(03:04:47) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Wise Traditions

Podcast Notes Key Takeaways * Check Out the Wise Traditions Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

The bottles of yellow oil on the supermarket shelves are labeled heart-healthy but they are in actuality damaging for our health (and the heart). These seed oils are unstable fats extruded from seeds that are not meant for human consumption. They are deodorized and colorized to make them look and taste appealing, but they are rancid and difficult to digest. They can (and do) lead to a host of health conditions from obesity, to cancer, to diabetes, to premature aging.

Sally Fallon Morell, president of the Weston A. Price Foundation, describes the issues with these oils: canola, safflower, sunflower, soy and more. Sally explains how to spot the seed oils in our foods and how to swap them out of the diet.

Visit Sally's website for her blog: nourishingtraditions.com

Follow WAPF on social media!

See our sponsors: Serenity Farm Bread, Paleo Valley, Optimal Carnivore

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Huberman Lab

Podcast Notes Key Takeaways * It’s not just the total hours and quality of sleep each night that matters, sticking to a sleep schedule ensures that you catch the window of growth hormone release * Sleep is well-regulated, don’t overthink things like waking up in the middle of the night to use the restroom or short periods of waking up unless you are chronically sleep deprived * If possible, don’t use an alarm clock – if it goes off and wakes you during a sleep cycle, this could lead to grogginess * A key part of adjusting sleep with PTSD or after a traumatic event: calm down the sympathetic nervous system prior to sleep so locus coeruleus can shut off and you can erase the novelty of the event * Sleep is terribly disturbed during opiate withdrawal and predicts relapse behaviors by changing endogenous opiate receptors and inducing firing of locus coeruleus when they should be calm

Read the full notes @ podcastnotes.org

My guest this episode is Gina Poe, PhD, a professor in the department of integrative biology & physiology at the University of California, Los Angeles (UCLA). We discuss her research exploring how sleep impacts learning, memory, hormones and emotions. She discusses tools to enhance your quality of sleep, increase deep sleep, rapid eye movement sleep and growth hormone release-- a key hormone for health, immune function and vitality. Dr. Poe explains how a specific brain area, the locus coeruleus, facilitates the processing of emotions, helps relieve traumas and how to maximize locus coeruleus function. She also explains sleep’s vital role in opiate addiction recovery and how anyone can determine their optimal sleep timing and duration. This episode is rich with basic science information and zero-cost tools to enhance quality and effectiveness of sleep for sake of mental health, physical health and performance.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Helix Sleep: https://helixsleep.com/huberman
Eight Sleep: https://eightsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Gina Poe
(00:02:52) LMNT, Helix Sleep, Eight Sleep, Momentous
(00:06:58) Sleep Phases, Perfect Night’s Sleep
(00:10:32) Can You Oversleep?
(00:14:50) Sleep Cycles, Sleep Spindles, “Falling” Asleep, Dreams & Memories
(00:19:01) Tool: Growth Hormone Release & Sleep
(00:22:05) Adolescence; Early Sleep, Alcohol & Sleep Spindles
(00:24:55) Middle Sleep States & REM, Schema, Waking at Night
(00:30:33) Deep Sleep, Dreams & Senses
(00:33:22) AG1 (Athletic Greens)
(00:34:37) Later Sleep, Paralysis, Sleepwalking, Sleep Talking
(00:36:47) Alarm Clock & Grogginess; Sleep Trackers, Brain & Sleep
(00:43:19) Early Slow Wave Sleep & “Washout”, Normal Sleep Cycle & Night Owls
(00:54:30) Locus Coeruleus, Learning & REM Sleep
(01:01:46) Post-Traumatic Stress Disorder (PTSD), Locus Coeruleus & Sleep
(01:06:13) InsideTracker
(01:07:31) Locus Coeruleus, Trauma & Sleep, Antidepressants, Norepinephrine
(01:12:29) Locus Coeruleus, Bedtime & Novelty, Estrogen & Trauma
(01:16:22)Sex Differences & Sleep
(01:19:12) Tool: Non-Sleep Deep Rest (NSDR), Insomnia, Meditation, Prayer
(01:27:42) Sleep Spindles, Learning & Creativity, P Waves & Dreaming
(01:34:51) Lucid Dreams, Reoccurring Dreams, Trauma
(01:44:11) Trauma Recovery, Locus Coeruleus & Norepinephrine, REM Sleep
(01:52:15) Opiates, Addiction, Relapse & Sleep
(02:02:45) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Momentous, Neural Network Newsletter, Social Media
Title Card Photo Credit: Mike Blabac
Disclaimer

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Huberman Lab

Podcast Notes Key Takeaways * The head and face are so heavily infused with blood vessels, so there is a spreading out of inflammatory response that triggers pain mechanisms and leads to headaches * Three primary origins of headaches: nerve based, muscle based, meningeal based * “Knowing what kind of headache you have is indispensable for the treatment of headache”– Dr. Andrew Huberman – to do this: understand the different types of headaches, pinpoint the type of headache you have and the tissues involved * Quality deep sleep reduces the frequency of headache and time to repair after brain injury + Raise baseline of health to reduce risk of headaches: sleep, sunlight at the right time of day, avoiding bright light at night, nutrition, exercise, healthy social connection * Omega-3 through diet or supplement (1g EPA per day) have potent effects on reducing pain, frequency, and intensity of hormonal based headaches related to menstruation * Use of essential oils for headache relief is not pseudoscience! Peppermint oil outperforms over the counter NSAIDs for treatment of headaches without the side effects

Read the full notes @ podcastnotes.org

In this episode, I discuss the causes and treatments of different types of headaches, including tension headaches, migraines, sinus and cluster headaches, as well as menstrual and other hormone-based headaches. I describe how to distinguish between the different headache types and how to select the right treatment, including prescription-based and non-prescription-based treatments, behavioral and nutrition-based approaches. I also explain the evidence and mechanisms supporting the use of omega-3 fatty acids, high dose creatine, peppermint oil, turmeric, acupuncture and more. Additionally, I touch on traumatic brain injury, the causes of photophobia, aura, and the link between spicy foods and thunderclap headaches. By the end of this episode, listeners and viewers will have a comprehensive understanding of headaches, their types and the best way to prevent and stop them.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Thesis: https://takethesis.com/huberman
LMNT: https://drinklmnt.com/huberman
Maui Nui Venison: https://mauinuivenison.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Huberman Lab Premium
https://hubermanlab.com/premium
Timestamps
(00:00:00) Headache
(00:03:51) Sponsors: Thesis, LMNT, Maui Nui, Momentous
(00:07:47) Headache Sources: Muscle Tension; Blood Flow & Meninges
(00:14:06) Headache Sources: Neurons; Inflammation & Sinus Headache
(00:23:21) 3 Neuron Types, Pain, Tension Headaches
(00:31:05) Tension Headaches
(00:33:25) AG1 (Athletic Greens)
(00:34:29) Migraine Headaches, Aura, Photophobia
(00:43:10) Cluster Headaches
(00:47:47) Hormone-Based Headaches, Menstrual Cycle & Menopause
(00:53:38) Traumatic Brain Injury (TBI) & Headache, Baseline Health
(01:02:08) Tool: Headache Treatment, Creatine Monohydrate & TBI
(01:12:22) InsideTracker
(01:13:55) Headache Treatment, Omega-3 & Omega-6 Fatty Acids (Linolic Acid)
(01:22:14) Tool: Omega-3 Supplementation, Omega-6 Fatty Acids & Inflammation
(01:28:11) Hormone Headache Treatment & Omega-3s
(01:31:24) Tool: Aura, Photophobia & Offsetting with Red Light
(01:44:15) Tool: Tension Headache & Botox Treatment
(01:49:43) Tool: Alternative Headache Treatments, Peppermint Oil, Menthol
(02:01:35) Tool: Tension Headaches Treatment & Acupuncture
(02:05:41) Tool: Migraine & Herbal Treatment, Caffeine Timing
(02:13:26) Tool: Migraine Treatments & Curcumin (Turmeric)
(02:18:00) Carolina Reaper Pepper & Thunderclap Headache
(02:24:21) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Social Media, Momentous, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Doctor's Farmacy with Mark Hyman, MD

Podcast Notes Key Takeaways * Check Out the Doctor’s Farmacy Episode Page & Show Notes

Read the full notes @ podcastnotes.org

This episode is brought to you by Rupa Health, InsideTracker, and Pendulum.

Of all the things we do each day, breathing is arguably the most important. While breathing’s most important job is to literally keep us alive, breathing can help in many more ways than just survival, including activating your parasympathetic nervous system, which helps slow your heart rate and lower your blood pressure.

In today’s episode, I talk with James Nestor, Dr. Louis Ignarro, Wim Hof, and Dr. Jim Gordon about using breathing to support your health.

James Nestor is an author and journalist who has written for Scientific American, Outside, The New York Times, and more. His latest book, Breath: The New Science of a Lost Art, was an instant New York Times bestseller. Breath explores how the human species has lost the ability to breathe properly—and how we can get it back.

Dr. Louis Ignarro is a medical research scientist who was awarded the Nobel Prize in Medicine for his breakthrough discovery of nitric oxide and how it positively impacts health and longevity. His groundbreaking research on nitric oxide paved the way for—among other innovations—Viagra. He is an award-winning Distinguished Professor Emeritus of Molecular & Medical Pharmacology at the University of California, Los Angeles, and has his PhD in pharmacology.

Wim Hof, also known as “The Iceman,” holds multiple world records for his feats of endurance and exposure to cold. He is the author of The Wim Hof Method: Activate Your Full Human Potential. The benefits of Wim’s method, now practiced by tens of thousands, have been validated by eight university research studies.

Dr. James Gordon, author of Transforming Trauma: The Path to Hope and Healing, is a Harvard-educated psychiatrist and the founder and CEO of the nonprofit Center for Mind-Body Medicine in Washington, DC. He is a clinical professor at Georgetown Medical School and was chairman (under Presidents Clinton and G.W. Bush) of the White House Commission on Complementary and Alternative Medicine Policy.

This episode is brought to you by Rupa Health, InsideTracker, and Pendulum.

Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.

Right now InsideTracker is offering my community 20% off at insidetracker.com/drhyman.

To receive 20% off your first Pendulum purchase, go to Pendulumlife.com and use code HYMAN.

Full-length episodes of these interviews can be found here:

James Nestor

Dr. Louis Ignarro

Wim Hof

Dr. Jim Gordon

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Huberman Lab

Podcast Notes Key Takeaways * Lifting weights, intervals, steady state exercise – everything works for fat loss because it’s increasing the demand for energy and increasing respiration rate + The exact method doesn’t matter as much as consistency * The bottom line to lose weight, you can play with the diet you prefer (whether it’s low fat, low carb, etc.) but what matters most is fewer calories – you have to be hypocaloric + Not to say that fat loss is a purely ‘calories in, calories out’ thing – remember, not all calories are created equal * Training fasted does not increase fat loss * “Maximizing fat burning and maximizing fat for exercise and maximizing fat loss over time are not the same thing at all.” – Dr. Andy Galpin + You will never be in a situation where fat is your only fuel source – with lower-intensity exercise, a greater percentage of fuel is coming from fat but total fuel expenditure is low (~60%) + But the opposite is true: with high-intensity exercise you will be almost 100% carbohydrate and 0% fat * Fat loss training protocol: combine hypertrophy and muscular endurance; 6-30 repetitions, deplete muscle glycogen; incorporate max heart rate intervals 30-60 seconds rest with a lot of recovery & repeat * You cannot turn muscle into fat or fat into muscle – they’re very different structures * “That idea of metabolic flexibility is using optimal fuel sources at optimal times, not maximizing fat loss.” – Dr. Andy Galpin * Do you need caffeine for workout fuel? It could be a sign you’re not good at utilizing carbohydrate stores for fuel (not to be confused with using caffeine for a better workout) * To get better at managing energy throughout the day: (1) make sure protein is stabilized; (2) ingest food in the right combinations with fiber and/or protein; (3) train at high intensity to get better at utilizing carbohydrates; (4) consume carbohydrates as fuel prior to workout * Lactate (to a threshold) is not the cause of fatigue – it’s actually fuel for the body: as fatigue increases, lactate will increase to try to buffer the negative consequences of energy generation * The best way to train for muscular endurance is to practice frequently to the point of failure * To improve anaerobic capacity, shoot for 5-6 minutes all out with max heart rate broken up into intervals (can vary length from 20-90 seconds with sufficient rest to allow a return to nasal breathing) * To train aerobic capacity: 5-15 minute bout of max effort, one round * If you want to hit anaerobic capacity and max aerobic capacity training: do 1 of each per week – one day can be shorter interval repeat and the other can be a 5-15 minute max effort push

Read the full notes @ podcastnotes.org

This is episode 3 of a 6-part special series on fitness, exercise and performance with Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton. He explains protocols to improve the various kinds of physical endurance: muscular endurance, anerobic capacity, maximum aerobic output, and long duration endurance. He also explains how the body uses different energy sources (carbohydrates, proteins, fats) during rest and exercise. He also explains the mechanisms underlying fat loss and how and why exercise accelerates rates of fat loss. We cover the many concepts related to endurance training and fat loss such as metabolic flexibility, breathwork training for exercise performance and recovery, lactate production and regulation, how to improve blood flow to muscles, anaerobic vs. aerobic metabolism, exercise fatigue, low-carbohydrate diets and fat loss, and how to combine different types of workouts to improve overall endurance. This episode in intended for everyone ranging from novice and recreational exercisers to elite endurance athletes. Anyone wishing to improve their physical health and performance stands to benefit from the information.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Levels: https://levels.link/huberman
LMNT: https://drinklmnt.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Endurance: Benefits, Mechanics & Breathing
(00:07:30) Tool: “Exercise Snacks”
(00:14:21) Momentous, Levels, LMNT
(00:18:01) Endurance Categories
(00:22:16) Fat Loss & Respiration; Carbon Cycles & Storage, Metabolism
(00:33:08) Exhalation Rates, Exercise & Fat Loss; Calories
(00:41:47) Cardiovascular Adaptations, Cardiac Output & Maximum Heart Rate
(00:47:03) AG1 (Athletic Greens)
(00:47:55) Excess Post-Exercise Consumption (EPOC); Exercise Intensity & Fat vs. Carbohydrate Energy Utilization
(00:59:35) Tool: Training for Fat Loss, Carbohydrate Stores, Liver Glycogen & Fatigue
(01:08:01) Metabolic Flexibility, Carbohydrates & Fat; Exercise & Flexible Fuel Utilization
(01:16:07) Muscle & Basal Metabolic Rate
(01:19:40) InsideTracker
(01:20:43) Assessing Metabolic Flexibility, Blood Glucose, Carbohydrates
(01:27:48) Caffeine, High-Carbohydrate Meals & Timing, Managing Daily Energy
(01:36:42) Cellular Energy (ATP) Production from Carbs; Lactate; Anerobic, Aerobic
(01:50:45) Lactate, Energy Production Buffer
(01:53:14) Fuel Sources & Exercise; Mitochondria, Oxygen Availability & Lactate
(02:02:50) Lactate for Exercise & Cognitive Performance
(02:04:33) Energy Production, Waste Management & Endurance Exercise; Insulin
(02:12:49) Protein & Fat Utilization for Energy; Exercise & Fat Loss
(02:21:20) Protein as Fuel Source, Fire Analogy
(02:26:39) Low-Carbohydrate Diet & Performance
(02:29:40) Muscular Endurance: Fuel Sources, Training & Capillarization
(02:37:30) Tool: Muscular Endurance & Modifiable Variables; Examples
(02:45:07) Anerobic Capacity: Fuel Sources, Training & Oxygen Utilization
(02:49:23) Tool: Cardiac Output, Heart Rate Zones & Breathing “Gear System”
(02:58:10) Tool: Anerobic Capacity & Modifiable Variables; Examples, Nasal Recovery
(03:11:45) Tool: “Sugarcane” Endurance Protocol
(03:14:02) Anerobic Capacity, Training Progression
(03:16:40) Tool: Maximum Aerobic Output, Training & Modifiable Variables
(03:21:58) Tool: Long Duration Endurance, Training, Circuits
(03:25:13) Long Duration Endurance, Capillarization, Fatigue & Breathwork, Technique
(03:29:10) Weekly Combination Training, Metabolic Flexibility & Longevity
(03:37:23) Tool: Mixed Endurance Training, Half Marathon Example
(03:47:33) Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Infinite Loops

After working at McKinsey and getting an MBA from MIT, Paul Millerd was succeeding well on a path that “made sense”. However, things started changing when he had a health crisis, which ended up with him embarking on a pathless path. Since 2017, he’s been tinkering with multiple side-hustles, writing newsletters, creating podcasts, traveling, and helping others join the pathless path.

Paul’s Twitter: https://twitter.com/p_millerd
Paul’s newsletter: https://boundless.substack.com/
‘The Pathless Path’ book: https://think-boundless.com/the-pathless-path/

Show Notes:

Having fun paying bills
Jumping off your fitness landscape
The first few years of being self-employed
Connecting with the subconscious self
Internet as an off-ramp
How to stir up curiosity
Lessons from DJing
The social construct of retirement
Internet economy requires showing up daily
Design for liking your life
Tinkering
Embracing laziness
Luxury of doing what you want
The shift from cynicism to optimism
Societal progress over the last decades
What’s next for Paul?

Books Mentioned:

The Pathless Path; by Paul Millerd
The Body Keeps The Score; by Bessel van der Kolk

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Huberman Lab

Podcast Notes Key Takeaways * “Being female is a health hazard; we have twice the rate of depression, insomnia, we’ve got 3-4x increased risk of multiple sclerosis, we’ve got 5-8x the risk of thyroid dysfunction.” – Dr. Sara Gottfried * Mainstream medicine is still silo-based; as long as this is true, there’s very little collaboration and addressing of network effect * Do blood work as soon as possible! Knowing & monitoring your bloodwork may change the arc of how you take care of yourself + Continuous glucose monitors are an excellent way to learn about yourself and address behavior changes – it teaches the patient to be their own physician * To maximize vitality and longevity: sleep, avoid excessive alcohol, address perceived stress, be mindful of eating well, avoid toxic relationships, move intentionally in ways that work for your body * Ranking most useful supplements for the general population (but remember, start with high-quality food first): fish oil, magnesium, vitamin D * Exercise tips: balance routine to 1/3 cardio + 2/3 strength training + Note, high levels of cardio can increase cortisol levels! * Early hormone replacement therapy should be strongly considered! The decline in estrogen which starts around 40-43 seems to be the driver behind cerebral hypometabolism (decline in brain function) + “Hot flashes and night sweats are a biomarker of cardiometabolic disease – they are a biomarker of increased bone loss, they are a biomarker of changes in the brain. So many of the symptoms that occur in peri-menopause are not driven by the ovaries, they’re driven by the brain.” – Dr. Sara Gottfried

Read the full notes @ podcastnotes.org

My guest is Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and clinical assistant professor of integrative medicine & nutritional sciences at Thomas Jefferson University. Dr. Gottfried specializes in hormone health, vitality and longevity using precision/personalized approaches. We discuss female hormone health, puberty, perimenopause, and menopause, hormone testing, the microbiome, stress related hormone challenges, their causes, and various treatments. We also discuss fertility, birth control and tools for improving microbiome health, treating PCOS, insulin management, and the best nutrition, supplementation, and exercise programs for women. While the episode focuses mainly on female hormones, males will also benefit from our discussion because it includes actionable tools suggested for managing stress, bolstering the gut microbiome, and immunity—all of which stand to improve overall health, vitality and longevity in males and females.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
ROKA: https://roka.com/huberman
Thesis: https://takethesis.com/huberman
LMNT: https://drinklmnt.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Dr. Sara Gottfried
(00:03:51) ROKA, Thesis, LMNT, Momentous
(00:07:50) Women, Family History, Heredity & Environment
(00:11:00) Puberty, Stress, Menstrual Cycles, Intrauterine Devices (IUDs)
(00:17:26) Tool: Sex Hormones, Microbiome, Estrobolome & Disease; Biomarker Testing
(00:25:11) Nutritional Testing; Vegetables, Microbiome & Disease
(00:31:13) AG1 (Athletic Greens)
(00:32:22) Microbiome, Prebiotics & Probiotics, Inflammation
(00:36:08) Microbiome Testing, Magnesium, Constipation & Thyroid
(00:42:25) Female Colonoscopy; Network Effect & Modern Medicine, Stress Factors
(00:45:13) Constipation, Stress & Trauma, Autonomic Balance
(00:55:35) Constipation Relief, Stress, Breathwork & Meditation
(01:02:58) Systemic & Societal Stress Unique to Females
(01:08:19) InsideTracker
(01:09:23) Testing & Future Behavior
(01:11:55) Polycystic Ovary Syndrome (PCOS) & Cardiometabolic Disease; Stress
(01:22:57) PCOS, Insulin, Glucose Monitoring and Management; Data Access
(01:29:48) Behaviors for Vitality; Exercise & Body Phenotype; Cortisol
(01:36:40) Cortisol Supplements: Ashwagandha, Rhodiola, Fish Oil, Phosphatidylserine
(01:42:36) Cortisol, Anxiety & Immune System; Adrenal Function, Resilience
(01:48:07) Tool: Omega-3 Fatty Acids, Inflammation, Specialized Pro-Resolving Mediators
(01:54:20) Oral Contraceptives, Benefits & Risks; Ovarian Cancer; Testosterone
(02:06:50) Fertility, Follicular & Anti-Mullerian Hormone (AMH) Assessments
(02:10:29) Menopause & Hormone Replacement Therapy; Women’s Health Initiative
(02:15:30) Perimenopause, Cerebral Hypometabolism, Metabolism & Estrogen
(02:21:49) Intermittent Fasting, Ketogenic Diet, Metabolic Flexibility
(02:23:29) Stool Testing
(02:25:32) Coronary Artery Calcium (CAC) Test, ACE Score & Disease
(02:31:56) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Neural Network Newsletter, Momentous
Title Card Photo Credit: Mike Blabac
Disclaimer

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Huberman Lab

Podcast Notes * The problem with aging isn’t just the preservation of muscle, it’s the preservation of muscle, power, and strength – you want to stand up, catch yourself from a fall, pick things up from the floor, etc. * Distinguishing strength and hypertrophy: + Strength relates to mechanics, the force capability of muscle, and firing the right muscle group in the right sequence + Hypertrophy is simply the size of the muscle (without consideration for function or strength) – hypertrophy training optimizes for muscle size, not muscle strength * “Protein ingestion alone is anabolic – it will help you grow muscle, independent of even moving.” – Dr. Andy Galpin + If you ingest protein + carbohydrates (fuel) + exercise, the benefits stack to maximize muscle growth * It’s important to understand your goal! You can put together a training program for any adaptation you want and avoid the ones you don’t want * “Volume is the primary driver in hypertrophy; intensity is the primary driver in speed, power, and strength.” – Dr. Andy Galpin * Non-negotiables for any training program to work:(1) adherence, (2) progressive overload, (3) individualization, (4) choosing the appropriate target * In general, a good rep cadence for strength training is 311 and a good cadence for hypertrophy is 312 (or you could even keep it 311 and manipulate other variables – it’s just a method choice) * General exercise breathing protocol: maintain a breath hold during the lowering/eccentric most dangerous part of the movement & exhale on the concentric portion * The main difference between a power or strength workout is the load – moderate load is power-based adaptation at high intent (moving fast; 30-70% 1RM); strength training is 70% 1RM or higher

Read the full notes @ podcastnotes.org

In this episode 2 of a 6-part special series, Dr Andy Galpin, PhD, professor of kinesiology at California State University, Fullerton and world expert on exercise science, explains optimal protocols for increasing strength and causing hypertrophy (muscle growth), as well as for increasing speed and power. He explains the training principles and underlying mechanisms for reaching these goals. Our conversation covers a breadth of training topics, including selecting the number of repetitions, sets, inter-set and inter-workout rest periods, warm-ups, exercise cadence, breathing, stretching, recovery, training frequency, overcoming plateaus, nutrition, and he gives specific examples of exercises for power, strength, and hypertrophy.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Eight Sleep: https://eightsleep.com/huberman
Levels: https://levels.link/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Benefits of Strength & Hypertrophy Training, Aging
(00:10:52) Strength & Hypertrophy Training, Aesthetics
(00:14:02) Momentous, Eight Sleep, Levels
(00:17:48) Strength vs. Hypertrophy Training: Adaptations
(00:22:42) Ligaments, Tendons & Resistance Training
(00:28:05) Bone Strength & Resistance Training, Age, Women
(00:32:38) Strength Training & Major Adaptations
(00:41:32) AG1 (Athletic Greens)
(00:42:25) Hypertrophy Training & Major Adaptations; Protein Synthesis
(00:45:56) Endurance vs. Strength Training & Cell Signaling, Protein Synthesis
(00:52:26) Muscle Hypertrophy, Sarcoplasmic Hypertrophy
(00:56:37) Muscle Physiology & Plasticity, Muscle “Memory”
(01:04:00) Non-Negotiables & Modifiable Variables of Exercise Training
(01:11:51) InsideTracker
(01:12:53) Tool: Speed & Power Training, “3 to 5” Approach, Periodization, Planning
(01:22:02) Warming Up & Training, Dynamic Movements
(01:30:55) Strength vs. Hypertrophy Repetition Cadence, Triphasic Training
(01:44:03) Tool: Breathing & Training, Valsalva Technique
(01:53:22) Tool: Training Auto-Regulation, Specificity vs. Variation, Prilepin's Chart
(02:02:35) Training to Failure, Exercise Selection & Recovery, Standardization
(02:13:45) Tool: Power vs. Strength Training & Modifiable Variables; Supersets
(02:24:22) Sets & Rest Periods; Stretching
(02:28:48) Tools: Power Training & Modifiable Variables; Examples
(02:30:16) Tools: Strength Training & Modifiable Variables, Cluster Sets, Dynamic Variable Sets
(02:40:44) Power & Strength Training Protocols
(02:43:37) Intention, Focus & Exercise
(02:47:29) Hypertrophy Training Program, Muscle Growth & Signaling
(02:55:12) Tools: Hypertrophy Training & Modifiable Variables; Examples
(03:03:02) Balanced Muscle Development & Hypertrophy
(03:09:04) Tools: Hypertrophy Training & Modifiable Variables; Splits
(03:23:08) “Non-Responders” & Exercise Plateaus, Volume
(03:27:06) Hypertrophy, Repetition & Rest Ranges, Muscle Failure, “Chaos Management”
(03:37:39) Frequency & Workout Duration, Splits
(03:44:52) Training Frequency, Infrequent Training, Intermediate Repetition Ranges
(03:55:22) Hypertrophy, Muscle Damage & Recovery
(04:01:15) Combining Cardiovascular & Hypertrophy Training, Interference Effect
(04:06:22) Hypertrophy Training Protocols
(04:12:06) Tool: Neck & Rear Deltoid Exercises, Stabilization & Hypertrophy
(04:14:42) Hypertrophy: Reps, Sets & Progression, “Hidden” Stressors, Exercises to Avoid
(04:21:09) Deliberate Cold Exposure & Hypertrophy vs. Strength
(04:26:41) Nutrition, Timing & Strength/Hypertrophy; Creatine
(04:38:04) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter
Title Card Photo Credit: Mike Blabac
Disclaimer

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Y Combinator

Podcast Notes Key Takeaways * Almost all the advice that’s written online about hiring is written for post product-market fit companies + However, most startups are pre-product market fit + They are reading advice for a stage that they are not at now, but odds are they will never be at * Michael Seibel believes that the number of employees is one of those fun stats that second-time founders react to differently than the first time * Founders have a unique skill set – as a founder, you know the problem better than anyone else, and you know how your product works better than anyone * So much of the startup is just reacting when things are horribly broken * Generally, you should start hiring only if it’s a post-product market fit scenario and things are going well and accelerating * Over-hiring leads to a high burn rate which leads to a lower financial “runway” * If you are post product-market fit, ignore everything said and hire away + If you are pre-product, double down on everything Harj, Michael, and Brad talked about + If you don’t know if you are post or pre, don’t hire people to figure that out (lol)

Read the full notes @ podcastnotes.org

Step inside the Group Partner Lounge to hear Y Combinator Group Partners Harj Taggar, Michael Seibel and Brad Flora discuss the many different mistakes founders make when they approach hiring for their startup and how to grow your team the correct way.

Apply to Y Combinator: https://www.ycombinator.com/apply/

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Modern Wisdom

Podcast Notes Key Takeaways * David Goggins has turned down millions in corporate speaking fees to fight remote wildfires in British Columbia earning $15/hr * If David wants to help people get better, then he must continue to get better himself; he cannot rest on his existing resume, he must add to it * How David Goggins does what he does: “At the end of the day I ask myself one question. ‘Can I take one more step?’ And usually, that answer is yes.” * The David Goggins One-Second Decision Theory says that it only takes one second for you to fail at what you are pursuing + Do not let your mind take control of you during that one-second * Despite running and completing a 240 mile race, David’s first 100-mile race was the most painful pursuit of his life * Goggins created a self-narrated mixtape of all the hate messages he receives and listens to it on repeat * People erroneously think that motivation is a constant; nothing is permanent, including motivation, which tends to come and go * You must learn to train your mind so it does not rely on motivation; learn to be your best self when you are least motivated * A typical day for Goggins: wake up at 5 AM, run at least 12 miles, hit the gym for 45 to 90 minutes, attend to daily obligations, stretch and meditate for two hours, get at least 7 hours of sleep * Confidence comes from the thing that you built; you must build belief and confidence * Trauma and devastation will come; you cannot allow it to be a barrier to whatever it is you want out of life * “Don’t ever be ashamed of anything you’ve ever done in your life. Face it, fix it, make it better.” – David Goggins * You will find peace if you go to war with yourself

Read the full notes @ podcastnotes.org

David Goggins is a retired United States Navy SEAL, ultramarathon runner, triathlete, public speaker and an author.

The ability to overcome challenges in life is one we will all need sooner or later. Make no mistake, discomfort is coming for you whether you're ready or not. Goggins happens to be one of the best individuals on earth at dealing with hard things and after a long time without any podcast appearances, I met him in Vegas to find out what new insights he's uncovered.

Expect to learn what most people get wrong about motivation, Goggins' thoughts on claims that SEAL selection is too hard, what the most painful experience of his life was, the danger of success making you soft, why he ran the MOAB 240 twice with no knee cartilage, why he recorded a mixtape of insults from the internet, how to overcome laziness, what David's entire daily routine looks like and much more...

Sponsors:

Get a Free Sample Pack of all LMNT Flavours with your first box at https://www.drinklmnt.com/modernwisdom (automatically applied at checkout)

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Extra Stuff:

Buy Never Finished - https://amzn.to/3Qvcdvs

Follow David on Instagram - https://www.instagram.com/davidgoggins

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

Never Finished: Unshackle Your Mind and Win the War Within

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A16z Podcast

Podcast Notes Key Takeaways * Social platforms will become a natural place for product discovery as platforms will ease the friction between inspiration, purchase intent, and completed purchases * China is mobile-only, compared to the U.S. which is mobile-first, so China tends to iterate on mobile features much faster than the U.S. * In 2019, two-thirds of Americans said they had a favorite local place they went to regularly. Four years later, that two-thirds has decreased to one-half. * Gaming bots have historically been scripted procedures but are increasingly becoming network-based AIs that are more convincing to humans * Multiplayer games of the future may consist of perfectly catered AIs specifically designed for each gamer * Brands will lean into the platforms that enable interoperability across platforms * Of the group of digital natives, Gen Z, and Gen Alpha, 2 in 5 already believe that self-expression via fashion is more important in the digital world than the physical * Generative AI will advance beyond “text to image” to more complex workflows, such as “text to SQL queries” or, eventually, “text to excel modeling” and more * Much of the truly useful data is actually proprietary enterprise data and is not widely available on the internet for AIs to train on * “If your company does not have an AI strategy, it should really be thinking about one yesterday.” – Sarah Wang * Fintech companies will need to strike a delicate balance between building with new technology rails while maintaining customer trust * Regardless of the platform shift, distribution is always key

Read the full notes @ podcastnotes.org

At the end of 2022, our team at a16z asked dozens of partners across the firm to spotlight one big idea that startups in their fields could tackle in 2023.

Emerging from this exercise came 40+ builder-worthy pursuits for the year, ranging from entertainment franchise games to precision delivery of medicine to small modular reactors, and of course loads of AI applications.

In our 2-part series, we’ll be covering 12 of these big ideas with the partners that shared them.

Here in part 1, we’ll cover Consumer, Games, and Enterprise, with a little Fintech sprinkled in. Listen in as we chat with Connie Chan, Anne Lee Skates, Jack Soslow, Doug McCracken, Sarah Wang, and Sumeet Singh.

And look out for part 2 dropping soon, covering Fintech, American Dynamism, and Bio & Health!

For the full list of 40+ ideas, check out the full article: https://a16z.com/2022/12/15/big-ideas-in-tech-2023/

Topics Covered:

(1:30) Breakthroughs in Buying (Finally!) - Connie Chan
(16:40) Unlocking the “Third Place” - Anne Lee Skates
(30:14) Games as a Neverending Turing Test - Jack Soslow
(46:09) The Metaverse Goes Fashion Forward - Doug McCracken
(59:24) Generative AI Advances Beyond “Text to Image” to Complex Workflows - Sarah Wang
(1:12:23) Embracing Large Language Models and Maintaining Trust - Sumeet Singh

Stay Updated:

Find us on Twitter: https://twitter.com/a16z

Find us on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

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Huberman Lab

Podcast Notes Key Takeaways * The same key hormones are involved in male and female puberty and reproduction: GnRH, LH, and FSH * Ovulation & menstruation is about creating the opportunity for fertilization to occur if sperm is within close enough proximity * Men: if you want to conceive in the next 90 days, avoid elevating body temperature (e.g., hot tubs, hot baths, sauna, etc.) to optimize testes temperature and sperm health * Many miscarriages, trisomy abnormalities, failures at fertilization, and birth defects occur because egg and sperm chromosomes are not properly pulled apart into haploids * There is evidence that heat from laptops and electronics on the lap are negatively impacting sperm count * Frequency of intercourse for conception: abstain from intercourse 2-3 days before ovulation; then on the day prior to ovulation or the day of ovulation, have as much intercourse as you can/want + Successful fertilization largely depends on the quality of the egg * Err on the side of conservative when trying to conceive and talk to OB/GYN at the onset of your desire to have children; the probability of conceiving naturally decreases throughout 30s due to the diminishing quality of eggs

Read the full notes @ podcastnotes.org

In this episode, I discuss the mechanisms by which human eggs and sperm are generated, the ovulatory/menstrual cycle, the conception process and overall fertility in males and females. I also explain how, regardless of whether you seek to conceive children, optimizing egg and sperm health is directly related to vitality and longevity. I cover the nutrition-based, behavioral, supplement-based and prescription approaches to optimizing egg and sperm health, the ovulatory/menstrual cycle and fertility. In addition, I explain lifestyle choices that greatly assist or harm fertility—several of which are very surprising. I provide science-based protocols for those trying to conceive children. The tools and principles I discuss can also improve overall vitality and longevity in all people, regardless of age.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Maui Nui: https://mauinuivenison.com/huberman
Eight Sleep: https://eightsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Fertility, Vitality & Longevity
(00:04:24) Maui Nui Venison, Eight Sleep, Momentous
(00:08:20) Eggs & Sperm, Genes, Fertilization
(00:18:28) Puberty: Gonadotropin Releasing Hormone (GnRH), Melatonin & Leptin
(00:23:38) Onset Trends of Puberty, Odors Effects
(00:31:24) Female Puberty, Luteinizing Hormone (LH), Follicle Stimulating Hormone (FSH)
(00:35:25) AG1 (Athletic Greens)
(00:36:34) Ovulatory & Menstrual Cycle
(00:40:36) Follicular Phase: Egg Maturation & Ovulation, FSH & Estrogen
(00:51:09) Luteal Phase: Progesterone & Estrogen, Menstruation
(00:58:14) Ovulation & Libido; Luteal Phase & Malaise; Individual Variability
(01:03:14) InsideTracker
(01:04:18) Sex Chromosomes, Sperm
(01:11:40) Tool: Testicular Temperature & Fertility
(01:17:22) Sperm Production, Seminal Fluid, Vasectomy
(01:24:07) Sperm Cells, Mitochondria & Motility, Intercourse Frequency & Fertilization
(01:28:31) Sperm Production, GnRH, FSH, LH & Testosterone
(01:36:21) Ejaculate Quality, Sperm Counts, Fertilization, Ectopic Pregnancy
(01:44:14) Tool: Sexual Intercourse Frequency & Fertilization
(01:53:24) Tools: Tracking Ovulation, Libido, Lubricants
(01:56:42) Fecundability: Egg Quality & Woman’s Age, Cumulative Pregnancy Rate
(02:08:17) Miscarriages, Chromosomal Abnormalities
(02:11:23) Female Fertility: Age, Follicle Testing & Anti-Mullerian Hormone (AMH) Testing
(02:18:51) Male Fertility: Sperm Analysis, Age
(02:24:52) Fertility & Hormone Analysis, Age
(02:29:07) Fertility Effects of Sleep, Cortisol/Stress, Cannabis/Nicotine & Alcohol
(02:42:40) Fertility, Sexually Transmitted Infections (STIs), Viral Infection & Cystic Fibrosis
(02:47:42) Tool: Testicular Temperature & Fertility
(02:51:26) Tool: Phones & Sperm Quality
(02:58:06) Deliberate Cold Exposure & Fertility, Testicular Temperature, Cortisol/Stress
(03:05:43) Fertility, Exercise & Mitochondrial Health; Intermittent Fasting
(03:14:46) Testosterone Replacement Therapy & Sperm Production; Supplements
(03:20:36) Sex Determination in Offspring, In Vitro Fertilization (IVF), Sperm Fractions
(03:32:23) Postcoital Female Position & Fertilization, Sperm Quality
(03:36:57) Cannabis & Sperm Motility, Libido, Pregnancy
(03:42:33) Acupuncture, Fertility & Pregnancy
(03:49:25) Fertility Supplements: L-Carnitine & Allicin, Coenzyme Q10
(03:56:18) Fertility Supplements: Inositol, Omega 3 Fatty Acids
(04:02:50) Supplements for Hormones: Tongkat Ali, Shilajit, Zinc
(04:13:02) Fertility & Prescription Medications
(04:16:44) Human Reproduction & Fertility
(04:20:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
Title Card Photo Credit: Mike Blabac

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Infinite Loops

Podcast Notes Key Takeaways * We are entering an exponential trajectory of technological progress and our antiquated minds cannot possibly keep up unless we change the stories, programming, and hardware * Technological progress is like a snowball rolling down a hill, picking up more matter and evolving as it goes * Today, we are operating on the programming that worked really well in caves and savannas but does not work quite as well in the massive groups that we find ourselves in now * Stories can help us overcome the deeply-rooted social wiring that does not always serve us * Negative storytelling appeals to our base emotion of fear, especially novel fear regarding things that new * The heretics working on the leading edge of technology must reframe their innovation’s impact with better stories * We may fall victim to a self-fulfilling prophecy of a tech dystopia if we do not get the stories right * Humans evolved during times of zero-sum conflict, so all of the stories we told around the campfire were zero-sum conflict-based stories * Upgrading the human operating system will not solve all the world’s problems, but it will create new and better problems that can also be solved * Humans control what pumps the gas or slams on the break for the AI, which are control measures that we barely have for ourselves * Our current system is optimized for growing GDP, not human flourishing * Reduce the flow of negative information into your mind and increase the volume of positive information in the world * Try to be optimistic about the future, and see yourself as a human on earth instead of being a member of a specific tribe

Read the full notes @ podcastnotes.org

Author, CEO of VUDU Marketing and digital nomad Sam McRoberts returns for his second appearance on Infinite Loops. This week, Sam and Jim discuss Sam’s latest book ‘The Grand Redesign’.
Part science-fiction, part operating manual for upgrading human OS, ‘The Grand Redesign’ touches on a number of recurring Infinite Loops themes, and is available for free online (see ‘Important Links’ section below).

Important Links:

The Grand Redesign
Sam’s Twitter
Sam’s Substack
The Thinker and The Prover
Tinkered Thinking’s winning entry to our ‘White Mirror’ competition

Show Notes:

Why Sam wrote the book
Is the Watcher a reliable narrator?
Interfering with complex systems
An overview of Social OS
Why we need White Mirror
The kindness pledge
Incentives and the Cobra Effect
How do we break the Shannon limit?
Jim’s movie idea
Improving the political and legal system
The opportunities of AI
Optimising our system for flourishing
Finding the hidden geniuses
Sam’s solutions; reaching the tipping point
Sam’s hopes for the book
MUCH more!

Books Mentioned:

The Grand Redesign; by Sam McRoberts
The Status Game: On Human Life and How to Play It; by Will Storr
Prometheus Rising; by Robert Anton Wilson
House of Cards: Psychology and Psychotherapy Built on Myth; by Robyn Dawes
The Lessons of History: by Will Durant and Ariel Durant
Happy: Why More or Less Everything is Absolutely Fine; by Derren Brown
The Inevitable: Understanding the 12 Technological Forces That Will Shape Our Future; by Kevin Kelly

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All-In with Chamath, Jason, Sacks & Friedberg

Podcast Notes Intro * Chamath Palihapitiya (@chamath), Jason Calacanis (@Jason), David Sacks (@DavidSacks), and David Friedberg (@friedberg) give their 2023 predictions on politics, business, and more! * Follow along with All-In Podcast Notes throughout 2023 to see which bestie is the most (and least) accurate

Read the full notes @ podcastnotes.org

(0:00) Bestie New Year catch-up!

(2:44) Prediction 1: 2023's biggest political winner

(17:25) Prediction 2: 2023's biggest political loser

(21:57) Prediction 3: 2023's biggest business winner

(30:34) Prediction 4: 2023's biggest business loser

(42:03) Prediction 5: 2023's biggest business deal

(52:41) Prediction 6: 2023's most contrarian belief

(1:03:03) Prediction 7: 2023's best-performing asset

(1:07:50) Prediction 8: 2023's worst-performing asset

(1:14:46) Prediction 9: 2023's most anticipated trend

(1:21:40) Prediction 10: 2023's most anticipated media

(1:27:07) Breaking news: OpenAI reportedly in talks to sell existing shares at a ~$29B valuation

Follow the besties:

https://twitter.com/chamath

https://linktr.ee/calacanis

https://twitter.com/DavidSacks

https://twitter.com/friedberg

Follow the pod:

https://twitter.com/theallinpod

https://linktr.ee/allinpodcast

Intro Music Credit:

https://rb.gy/tppkzl

https://twitter.com/yung_spielburg

Intro Video Credit:

https://twitter.com/TheZachEffect

Referenced in the show:

https://www.wsj.com/articles/citadel-posts-record-revenues-for-hedge-fund-securities-operations-11672942665

https://www.reuters.com/world/saudi-arabia-gathers-chinas-xi-with-arab-leaders-new-era-ties-2022-12-09/

https://www.nytimes.com/2023/01/03/business/europe-natural-gas-prices.html

https://www.nytimes.com/2023/01/04/technology/salesforce-layoffs.html

https://www.wsj.com/articles/amazon-to-lay-off-over-17-000-workers-more-than-first-planned-11672874304

https://twitter.com/DavidSacks/status/1598076726671642624

https://www.nytimes.com/2022/12/30/world/asia/xi-putin-china-russia.html

https://twitter.com/JenniferJJacobs/status/1611052287954149377

https://www.bloomberg.com/news/articles/2023-01-03/blackstone-s-breit-gets-4-billion-from-university-of-california

https://www.nbcnews.com/politics/congress/gop-rebels-block-kevin-mccarthy-defiance-trump-rcna64280

https://www.wsj.com/articles/chatgpt-creator-openai-is-in-talks-for-tender-offer-that-would-value-it-at-29-billion-11672949279

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Huberman Lab

Podcast Notes Key Takeaways * Creativity is closer to magic than it is to science * Strictly adhering to “how things are supposed to be done” undermines the creative process * Understand how you feel in the face of other voices without second-guessing yourself * Know how you feel, and own your feelings * The most important part of the creative process is having the ability to stay present in the work * The creative process: “I am doing me, and I am showing you who I am, and you can like it or not but either way, this is still how I see it.” * The artist’s superpower is to accept that he does not know anything * Any external information that undermines the clarity of that connection is probably bad for the art * The physical world is constrained by the laws of physics, but the imagination is unconstrained; the work sits somewhere between these two * Rick has a sense of anxiety when he starts a new project because he knows that whatever is going to happen is completely out of his control * “Our whole lives are reacting to things, making up a story of what we think may have happened without realizing that’s what we’re doing, and then living the rest of our lives as if that thing that we made up really happened. And we never know.” – Rick Rubin * Challenge your assumption that the way you work is the best way, simply because it is the way that you have done it before * Do not get comfortable with thinking you know how it works just because you get the outcome that you want * The world gives you creative clues all the time if you are paying attention; the universe is on the same team as creativity

Read the full notes @ podcastnotes.org

My guest is Rick Rubin, one of the most renowned music producers of all time, known for his work with a wide range of artists, including Run DMC, Public Enemy, Beastie Boys, Red Hot Chili Peppers, JayZ, Adele, Johnny Cash, LL Cool J, Slayer, Neil Young, Kanye West, Tom Petty, and many more. He is also the author of a new book, "The Creative Act: A Way of Being," which explores the creative process and how to access creativity. We discuss topics such as finding inspiration, the role of feelings as guideposts, learning from observing nature, balancing self-doubt and anxiety, and adopting new perspectives to channel the creative process. Rick also shares his thoughts on using deadlines, eliminating distractions, and how our experiences and emotions influence the creative process. Additionally, we discuss his love for professional wrestling. Our conversation can be applied to any activity or profession to access creativity.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Maui Nui: https://mauinuivenison.com/huberman
Thesis: https://takethesis.com/huberman
WHOOP: https://join.whoop.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Rick Rubin
(00:04:08) Maui Nui Venison, Thesis, WHOOP, Momentous
(00:08:23) Creativity & Ideas, Cloud Analogy
(00:12:26) Language & Creativity; Kids
(00:17:36) Feelings & Creative Ideas
(00:22:01) Rules, Choice & Art; Personal Taste & Other’s Opinions
(00:30:20) Changing Perspective & Creativity
(00:33:55) AG1 (Athletic Greens)
(00:35:04) Scientific Knowledge; Opinions & Art
(00:41:27) Finishing Projects; The Source & Nature
(00:47:40) Perception Filters, Contrast & Novelty
(00:58:42) Music & Identity, Evolving Tastes
(01:03:03) InsideTracker
(01:04:14) Focus, Disengaging & Subconscious; Anxiety
(01:13:22) Collaboration, Art & Rigorous Work
(01:18:26) Process & “Cloud”; Perception & Storytelling
(01:29:13) Limited Resolution, Considering the Inverse
(01:35:38) Wrestling, Energy & Reality; Dopamine
(01:49:43) Wrestling, Style & Performance
(01:52:40) Resetting Energy & Nature; Nostalgia
(02:01:56) Sleep, Waking Up & Sunlight, Capturing Ideas
(02:08:16) Creative Work Phases; Structure & Deadlines
(02:15:32) Self-Doubt & Performance
(02:19:13) Predictability & Surprise, Authenticity
(02:25:02) Past Experiences, Other’s Opinions
(02:29:42) Public Opinion & Science: Light, Acupuncture & Nutrition
(02:39:44) “Look for Clues”, Belief Effects
(02:46:25) Attention, Emotion & Art
(02:48:07) Mantra Meditation, Awareness Meditation
(02:57:33) Rick Rubin Questions, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
Title Card Photo Credit: Mike Blabac

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Feel Better, Live More with Dr Rangan Chatterjee✓Claim

Podcast Notes Key Takeaways * Pneumonia, cancer, even headache, etc. are symptoms of a collapse of biodiverse balance * We need cooperation, not competition – biodiversity creates new possibilities and avenues to thrive * You have to be present and listen to yourself and believe you are enough to achieve health – your disease status, awards, career status, etc. are not your identity * We’ve outsourced who we are and become dependent on other people to tell us – the further we separate ourselves from nature, the sicker we become * “Death gets in the way – it’s out fear of death that leads to this reductionist behavior of short-term decision making.” – Dr. Zach Bush * We’re so out of tune that our immune response to a normal stimulus (virus) is chaos * Get back in tune with self and nature: spend time in solitude every day to connect to self, walk barefoot on soil for a few minutes daily * The gut microbiome seems related to all human chronic diseases – glyphosate destroys tight junctions in the gut worse than antibiotics and medications * “To feel better, all of us are going to have to feel more.” – Dr. Zach Bush

Read the full notes @ podcastnotes.org

I believe that conversation matters; that long form nuanced conversation is what we need now more than ever, to make the world a better place. And for me, part of that means exposing ourselves to new ideas, new concepts and new ways of thinking that we may previously have not been exposed to. This week’s guest on my Feel Better Live More Podcast is someone who fits that bill perfectly.

Dr Zach Bush is a medical doctor and founder of the non-profit Farmer’s Footprint, created to find root cause solutions for human and ecological health. His passion for education reaches across many disciplines, including genomics, the immune system, and gut brain health.

Zach spent many years as a conventional doctor, specialising in internal medicine, endocrinology and hospice care. Disillusioned with the state of Western medicine, he began taking an integrative approach, studying the body’s microbiomes in relation to health, disease and food systems. Today though, Zach describes his life and work as ‘dedicated to the health of humanity and the planet we call home’.

In this conversation, Zach makes the case for a revolution in how we understand ourselves, our fellow humans, our healthcare and farming systems – and how we save the world. This episode is a rollercoaster ride through biology, physics, philosophy, economics and environmentalism – all sprinkled with a good dose of inspiration.

Zach and I share the view that healthcare needs radical change. It can no longer be about doctors telling patients what’s wrong and prescribing drugs and treatments that don’t look at the whole person.

We discuss how traits of ego, individualism and competition aren’t really human at all. And Zach explains how the realisation that all living beings are energetically connected and interdependent is the key to transformation – we cannot thrive as one species if we wipe out others.

We also talk about saving our soil and our food systems through regenerative agriculture, and encouraging individuals, farmers and big industry to work together to save the internal and external ecosystems that none of us could live without.

Yes, these are big topics. But ultimately, Zach’s message is one of hope. He’s not afraid to put forward big solutions, and they’re all made up of steps each one of us can start taking from today.

This is a really special conversation. It's honest, evocative and at times, provocative. I hope you enjoy listening.

Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.

Thanks to our sponsors:

https://www.athleticgreens.com/livemore

https://www.vivobarefoot.com/livemore

https://www.leafyard.com/livemore

Show notes https://drchatterjee.com/298

DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or other qualified health care provider regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

Hosted on Acast. See acast.com/privacy for more information.

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Huberman Lab

Podcast Notes Key Takeaways * Ashwagandha is a potent adaptogen that can help buffer stress but don’t take it in the morning! We want cortisol high in the morning to set the tone for the day; try your first dose in the early afternoon and second in the evening * Cycle adaptogens through periods of stress and avoid taking for more than 30 days without taking a break

Read the full notes @ podcastnotes.org

Welcome to a sneak peek of the third Ask Me Anything (AMA) episode, part of Huberman Lab Premium.
The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.
Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium
Timestamps
(00:00:00) Introduction
00:00:00 Introduction
00:01:27 Adaptogens [Justine Bevilacqua]
00:29:42 Huberman Lab Premium
In the full 1.5 hour+ AMA episode, we discuss:

Caloric restriction in fertile women

Cognitive load limits

Potential risks of Bluetooth, Wi-Fi, EMFs

Creatine and aging

Title Card Photo Credit: Mike Blabac
Disclaimer

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My First Million

Podcast Notes Key Takeaways * Shaan Puri’s takeaways from the San Diego party: storytelling wins, he should leave the house more often, and the life phase a person is in dictates their energy and pursuits * Everyone at the party was impressive, but the ones that knew how to tell a story were the ones that stood out and made the most connections * The storytelling “sizzle” makes you memorable whereas simply listing facts about yourself or your business does not * One or two focused entrepreneurs with no money can do more in six months than a 50-person team at a large organization with millions of dollars, according to Sam Parr * The zero-to-one creative types are probably not working at the big company, and the mid-level managers do not want to take unnecessary risks and fail * It is common for a startup’s velocity of progress to dramatically slow post-acquisition, which is not always bad on net * After selling your startup and joining the company that acquires it, you trade entrepreneurial anxiety for bureaucratic frustration * It is much easier to launch something as a startup because you are beholden to no one * Big companies have the mindset of an ultra-marathon runner whereas startups have the mindset of a sprinter * Mistakes made by big companies cost more in terms of money, reputation, and time compared to mistakes made by lean startups * The best ideas are things that sound like bad ideas but are actually good ideas, paraphrasing Peter Thiel

Read the full notes @ podcastnotes.org

Episode 405: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about what happens when Shaan leaves the house and meets up with other founders, the power of storytelling, the things you learn when you sell a company and how to hire a researcher.
Want to see more MFM? Subscribe to the MFM YouTube channel here.

Links:
Alpha Paw
Genius Litter
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:
(04:20) - Shaan leaves the house and meets cool people
(13:15) - When Ramon pretended to be an electrician
(18:30) - Power of storytelling
(21:25) - Age and perception
(28:25) - Frame break
(30:10) - Things you learn when you sell a company
(46:05) - How to hire a researcher

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * If MrBeast knew he was going to die soon, he would make a decade worth of content and schedule-upload the videos so they would continue to come out after he is dead * “Whatever makes the best video” is the answer to any content creation or production strategy * The criteria for a good title: “If someone reads it, do they have to watch it?” * It is very unlikely that Twitter, or any other platform, will be able to pay out higher CPMs than YouTube * Going viral on YouTube is a learnable skill, it is not random * If you have zero videos on your channel, your first ten videos are not going to get views * Do not over-strategize if you are a beginner; just get to work and start uploading * When someone tells you something is not possible, go through all the variables and eliminate them yourself * Subscribers are a vanity metric; most of your views come from the home feed, not the subscriber feed * The optimal way to respond to a video that does poorly is to remove emotion from the equation and objectively evaluate what went wrong * Entrepreneurs must engage in activities that recharge their batteries during their downtime * Throw the conventional stuff out the window and focus on what is actually practical for your business * “Hopefully there is a day where I can give away a billion dollars in a video.” – MrBeast * The people you are around dictate your outcome; be extremely selective about who you spend your time around * “You are crazy until you are successful. Then you are a genius.” – MrBeast

Read the full notes @ podcastnotes.org

MrBeast is a legendary YouTube creator. Please support this podcast by checking out our sponsors: – House of Macadamias: https://houseofmacadamias.com/lex and use code LEX to get 20% off your first order – Eight Sleep: https://www.eightsleep.com/lex to get special savings – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: MrBeast Main Channel: https://youtube.com/@MrBeast MrBeast Reacts: https://youtube.com/@BeastReacts MrBeast Gaming: https://youtube.com/@MrBeastGaming MrBeast Philanthropy: https://youtube.com/@BeastPhilanthropy MrBeast’s TikTok: https://tiktok.com/@mrbeast MrBeast’s Twitter: https://twitter.com/MrBeast MrBeast’s Instagram: https://instagram.com/mrbeast Feastable’s Website: https://feastables.com MrBeast Burger’s Website: https://mrbeastburger.com MrBeast’s Merch: https://shopmrbeast.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT

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A16z Podcast

Podcast Notes Key Takeaways * Check Out the a16z Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

with @robertiger @cdixon @smc90

A wide-ranging conversation with Bob Iger on the interplay between technology, content, and distribution; as well as Bob’s journey -- and that of various creators! -- especially as the industry evolved from TV and cable to the advent of the internet/ web 1.0 to 2.0 to briefly touching on web3 and other emerging technologies. As well as topics top of mind for all company and community builders: from build vs. buy and the innovator's dilemma, to managing creativity, decentralization, remote work, and much more.

Subscribe to web3 with a16z: https://podcasts.apple.com/us/podcast/web3-with-a16z-crypto/id1622312549

Stay Updated:

Find us on Twitter: https://twitter.com/a16z

Find us on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app: https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

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Honestly with Bari Weiss ✓ Claim

Podcast Notes Key Takeaways * Suffering does not prove you are a good parent – in pregnancy or parenthood * Don’t make decisions for your family based on what you think you should be doing or what others are doing – make decisions that make sense for your family * Distinguish between changing guidelines in response to large-scale evidence (e.g., sleeping on back vs stomach) versus changing guidelines based on sensationalized information * Similar to what we see with other public health issues, there is minimal nuance in the information disseminated about how to navigate pregnancy, breastfeeding, child development, and parenting

Read the full notes @ podcastnotes.org

When my wife Nellie was pregnant last year, we became obsessed with Economist Emily Oster’s book, Expecting Better: Why the Conventional Pregnancy Wisdom Is Wrong–and What You Really Need to Know. Amidst a barrage of conflicting and confusing pregnancy advice, Oster laid out the data on everything we needed to know. Despite what doctors said, sushi, cheese, and the occasional glass of wine were all okay during those nine long months. It gave us the much needed calm we needed during a time of so much uncertainty.

With her two subsequent books Cribsheet and The Family Firm, Oster popularized a new phenomenon that has defined our generation of parents: data-driven parenting. It ditches the long lists of paternalistic rules, and instead examines peer-reviewed evidence and lets parents make their own informed decisions about their kids based on risks and tradeoffs.

Nowhere was the Oster mentality more front and center, and more divisive, than during Covid. She argued very early on in the pandemic for less draconian and more nuanced policies. She wrote pieces in the Atlantic like, Schools Aren’t Superspreaders and Your Unvaccinated Kids Is Like A Vaccinated Grandma, when those words were considered heresy. And while she made quite a few enemies on the left over the last few years, recently she wrote Let’s Declare A Pandemic Amnesty, and earned herself some enemies on the right as well.

Today, my wife Nellie Bowles joins me to talk to Oster about why a Harvard-educated economist at Brown University decided to become a parenting guru, how she used her parenting framework to become a leading expert on pandemic policies, and the unwinnable position of… actually following the science.
Learn more about your ad choices. Visit megaphone.fm/adchoices

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Masters in Business

Podcast Notes Key Takeaways * “I’m a client guy. No one wants to drink alone. So if he’s drinking, or if she’s drinking, I’m drinking.” – John Mack * John came from a small predominantly Baptist town in North Carolina; the party scene of 1970s Wall Street was a culture shock for him * Lessons learned from the bond desk: be upfront, focus on your clients, and don’t get drunk at lunch (but occasionally do) * “At the end of the day, it’s all about trust. And it’s all about delivering on what you say you are going to do.” – John Mack on building business relationships * Globalization and technology changed Wall Street more than anything else * In the 1970s, Wall Street bankers would go out to lunch for hours and not miss anything; today, bankers can’t leave their desk * John Mack tried to create a “One Firm, Firm” culture that reduced information silos and encouraged collaboration * Anyone with a personal fiefdom is terrible for a firm trying to create a strong culture * Advice for college graduates interested in finance: get your foot in the door, figure out how to get to know people in the company that you want to work for, perform well in your current job, and get an accounting degree or an MBA if you want to be an M&A specialist * Hold onto the great companies that you invest in

Read the full notes @ podcastnotes.org

Bloomberg Radio host Barry Ritholtz speaks with the legendary John Mack, former chief executive officer and chairman of the board at Morgan Stanley. His memoir of his life and 34-year tenure at Morgan Stanley — “Up Close and All In: Life Lessons From a Wall Street Warrior” — was published in October.

See omnystudio.com/listener for privacy information.

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My First Million

Podcast Notes Key Takeaways * Check out My First Million Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Episode 370: Sam Parr (@TheSamParr) talks to best-selling author, podcaster, bookstore owner, and former marketing director for American Apparel, Ryan Holiday (@RyanHoliday), about how to make money in publishing, creating a masterpiece, and investing in a ghost town.

Links:
Ryan Holiday
Trust Me I'm Lying: Confessions of a Media Manipulator
Brass Check
The Painted Porch Bookshop
Vinyl Me, Please
Ghost Town Living
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:
(03:55) - Does the bestseller list still matter?
(05:30) - Breaking down the #s of the publishing industry
(29:20) - How big is your team?
(35:10) - Who do you admire?
(44:40) - The pros and cons of reality distortion fields
(50:40) - Ryan's ghost town

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Huberman Lab

Podcast Notes Key Takeaways * “Behavioral tools form the foundational layer of all tools for mental health, physical health, and performance. Second to that, the next layer is nutrition. No amount of supplementation or non-prescription or prescription compounds can ever compensate for poor nutrition.” – Dr. Andrew Huberman + Nutrition is fundamentally important for obtaining basic nutrients, micro-, and macronutrients – supplements should be used to augment or support behavioral tools and nutrition * General approach to vitamin & mineral supplements: (1) is the cost within the range you can afford and want to pay; (2) are you able to cover needs just from food (you want most food to come from minimally or non-processed foods) * Three questions to ask yourself before starting supplementation: (1) how’s your sleep? (2) how’s your nutrition? (3) what’s your budget? * Unless you are supplementing for foundational support (vitamins, minerals, foundational compounds, adaptogens, probiotics, prebiotics), focus on single-ingredient formulated supplements for the most power and control overdose * Don’t try everything at once when trying to address a specific problem! Instead, try one supplement for one week (without varying anything else) than the other to see which works best for you – then see how well the combination works * Important note for women seeking fertility and hormone support: depending on the phase of your menstrual cycle, supplements will impact you differently since hormones are naturally fluctuating – it’s critical (for everyone, not just women) to take single-ingredient supplements so you can dose accordingly * If the budget is around $100 per month: don’t focus on trying to improve one specific area or category; instead, focus on buffering and enhancing foundational nutrition, adaptogens, probiotics, prebiotics, and digestive enzymes – check out Athletic greens

Read the full notes @ podcastnotes.org

In this episode, I explain how to design a supplementation protocol to support maximum mental and physical health and performance depending on your specific needs, nutrition, lifestyle and finances. When most people hear about “supplements,” they think they are vitamin supplements, but there are many compounds that are powerful and sold over-the-counter that can enhance our health in performance and that can’t be obtained from foods. First, I discuss “foundational” supplements to support overall health, including water and fat-soluble vitamins, minerals, digestive enzymes, adaptogens, and prebiotics/probiotics. Then I explain how to use single-ingredient supplements to enhance specific aspects of your physiology, such as aiding sleep, cognitive enhancement, and focus supporting healthy hormone levels (e.g., testosterone, estrogen and growth hormone, thyroid). Finally, I explain when it makes sense to add supplements to your lifestyle and discuss how best to use supplements, including how to determine dosage, sourcing, continuous schedules and cycling, and how to layer different supplements most effectively. This episode will explain how to design the safest, most biologically effective, cost-effective supplementation protocol to meet your particular goals and support your overall health, including vitality and longevity.
For the full show notes, visit hubermanlab.com.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
LMNT: https://drinklmnt.com/huberman
Helix Sleep: https://helixsleep.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
Timestamps
(00:00:00) Supplements
(00:03:38) Hierarchy of Tools/Interventions, Developing a Supplementation Protocol
(00:11:51) Momentous, LMNT, Helix Sleep
(00:15:38) Role of Supplements, Foundational Supplements, Water/Fat-Soluble Vitamins
(00:21:07) Supplement Considerations: Cost, Nutrition & Schedule
(00:25:25) Foundational Supplements, Digestive Enzymes, Adaptogens
(00:28:04) Gut Microbiome, Probiotics/Prebiotics & Nutrition
(00:33:06) Supplements for Gut Microbiome, Brain Fog
(00:35:59) InsideTracker
(00:36:44) Adaptogens & Broad-Spectrum Foundational Supplements
(00:38:35) Core Supplement Questions & Meeting Foundational Needs
(00:43:45) Supplements to Support Sleep: Myo-Inositol, Theanine
(00:50:52) Supplements for Falling Asleep: Magnesium Threonate/Bisglycinate, Apigenin
(00:55:55) Melatonin Caution
(00:58:11) Supplement Dependency?, Placebo Effects
(01:02:45) AG1 (Athletic Greens)
(01:03:53) Nutrition & Behavior for Hormone Health
(01:08:59) Hormone Health: Shilajit, Ashwagandha, L-Carnitine, Maca Root
(01:12:48) Growth Hormone: Behaviors, Arginine, Prescriptions
(01:16:04) Testosterone/Estrogen: Fadogia Agrestis; Bloodwork
(01:23:06) Testosterone Supplement: Tongkat Ali, Libido
(01:27:24) Menstrual Cycle, Birth Control & Fertility
(01:30:54) Cognitive Enhancement & Focus, Sleep, Stimulants: Caffeine
(01:36:57) Adrenaline & Stimulants: Yohimbine, Rauwolscine
(01:38:55) Adjusting Neurotransmitters: Alpha-GPC, L-Tyrosine; Layering Supplements
(01:43:58) Cognitive, Mood & Metabolic Support: Omega-3 Fatty Acids
(01:47:25) Food-Mimic Supplements, Protein
(01:50:09) Kids, Aging & Supplements
(01:55:25) A Rational Supplementation Protocol
(01:58:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network Newsletter
Disclaimer
Title Card Photo Credit: Mike Blabac

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Big Questions with Cal Fussman

Podcast Notes Key Takeaways * “The head talks to the heart. And the heart talks to the feet.” – Pele * Growing up, Pele played soccer in the streets by filling a large man’s sock with crumpled newspapers to create a ball * He was originally nicknamed “Pele” as an insult; his friends mocked him for not being able to pronounce the name of the goalie on his father’s team, “Bile” * At the age of 17, Pele helped Brazil win its first World Cup – a victory that brought the nation together like it had never been before * Pele once halted a civil war for 48 hours because both sides wanted to watch him play * Rice and beans remained Pele’s favorite food until the day that he died * Pele brought love and connection to the world like few athletes have ever been able to do

Read the full notes @ podcastnotes.org

On the day of Pele’s burial, Cal goes to the archives for an interview he did with the man many consider to be the greatest soccer player of all time. This podcast gets to the essence of the Brazilian superstar who connected with almost everyone on the planet. Not only did Pele make everyone smile, he once halted a war. After three years of disconnection due to the pandemic, we need to connect now more than ever. Pele shows us how.

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Rich Roll Podcast

Podcast Notes Key Takeaways * Check Out the Rich Roll Episode Page and Show Notes

Read the full notes @ podcastnotes.org

As 2022 comes to a close and a new year beckons, we are presented with an opportunity to reflect on the past twelve months. Explore new aspirations. And set intentions for the year to come. Allow me to indulge this truth by introducing Part Two of my annual yearbook—an auditory anthology of the year’s most compelling conversations. Enjoy the best of the year.

Guest List + Full Episode Links:

RRP 692: Malcolm Gladwell
RRP 723: Mel Robbins
RRP 715: Casey Neistat
RRP 718: Whitney Cummings
RRP 695: Peter Attia, MD
RRP 678: Gemma Newman, MD
RRP 702: Dr. Gabor Maté
RRP 714: Robynne Chutkan, MD
RRP 703: Max Fisher
RRP 660: Sylvia Earle
RRP 701: Ken Rideout
RRP 694: Colin O’Brady & Jenna Besaw
RRP 705: Paul Conti, MD
RRP 670: Earthling Ed Winters
RRP 681: Chip Conley

Show notes + MORE

Watch on YouTube

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Today’s Sponsors:

Levels: levels.link/RICHROLL

Navitas Organics: navitasorganics.com/richroll

Whoop: WHOOP.com

BetterHelp: BetterHelp.com/richroll.

Athletic Greens: athleticgreens.com/richroll

Peace + Plants,

Rich

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Infinite Loops

Podcast Notes Intro * O’Shaughnessy Ventures (OSV) is a company that invests in creators in the areas of art, science, and technology to help promising creators and their inspiring ideas succeed * For most of human history, a genius was born, lived, and died, and no one knew a thing about him or her; today’s technology changes that * The Great Reshuffle: Jim’s thesis that all the old business models are collapsing, and that very different, new ones are taking their place * “I believe that AI is the third technology revolution.” – Jim O’Shaughnessy * We need as much cognitive diversity as possible for technologies like AI to work; it is currently very Western-centric * Humans cannot prophesize future knowledge, and thinking that we can is a bug in the human operating system * Big Tech used the AI algorithm to maximize revenue, but these objective functions can also be used to maximize things like creativity and happiness * The guiding principle for OSV: asymmetric opportunities that are win-win * Every system other than capitalism – many of them religions – promised people that they would be fed and housed, and they all failed over the millennia * Jim believes the free market system succeeds because it is most aligned with human biology and the world * Traditionally, networks were where you went to school and where you grew up; but today, networks are being redefined as geography, time, and space all collapse * Luck exists, and if you’re reading this you probably hit the cosmic lottery, but you must still play the hand that you are dealt * Money is a technology that is used to bring ideas to life

Read the full notes @ podcastnotes.org

We’ve landed.

After 3 months of stealth mode, sneak-peeks, and surprise announcements, we have finally hit launch day.

In this special episode of Infinite Loops, hosted by Patrick O’Shaughnessy, Jim chats through the rationale behind founding OSV, the positive impact he wants it to have on the world, and the ways you can get involved.

Important Links:

OSV’s Website
Jim’s Twitter

Show Notes:

The origins of OSV
Why OSV does not invest third parties’ money
The story of Jim’s investment in Stability AI
What has surprised Jim the most about the world of AI
What OSV will look like on 1 January 2023: the four verticals
Assembling the OSV team
OSV’s objective function
Where the majority of Jim’s energy will be directed
How you can get involved with OSV

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * Check out The Drive Episode Page & Show Notes

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Sign Up to Receive Peter’s Weekly Newsletter

Chris Hemsworth, best known for his role as Thor in the Marvel movies, joins Peter to discuss his recent work in the docuseries called Limitless. In the docuseries, Chris undertook extreme challenges to explore his physical and emotional limits and gain insights into longevity. In this episode, Chris discusses these many challenges—from fasting to arctic swims to 100-foot rope climbs—as well as the insights that he gained from each. Peter, who also played a role in the docuseries, guides Chris through the science of longevity, including what Chris’s APOE-ε4 genotype means for his risk of Alzheimer’s disease. Additionally, Chris describes how his outlook on health, happiness, work-life balance, and more have changed from his experience on Limitless.

We discuss:

Limitless: how Chris got involved and his overall experience filming the docuseries [3:00];
“Fasting” ‒ ep. 3 of Limitless in which Chris attempts a 4-day fast [8:15];
“Shock” ‒ ep. 2 of Limitless in which Chris swims in the Arctic Ocean [12:15];
Cold exposure: the potential physical and mental benefits [19:30];
“Strength” ‒ ep. 4 of Limitless in which Chris explores how muscle can improve longevity [21:15];
The APOE-ε4 genotype and Alzheimer’s disease risk [31:30];
How Chris uses sauna [39:45];
“Acceptance” - ep. 6 of Limitless in which Chris explores the meaning of life by contemplating death [42:15];
Chris’s new perspective on work-life balance [52:00];
“Stress-Proof” - ep. 1 of Limitless in which Chris learns about the impact of stress and how to manage it [54:30];
Chris reflects on his intrinsic motivation driven by both fear and purpose [58:00];
Chris reflects on his career arc and how his presence as an actor has evolved [1:01:15];
How Chris’s outlook has changed since filming Limitless [1:05:00]; and
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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Starting Greatness with Mike Maples

Podcast Notes Key Takeaways * Boom Supersonic is the first entrepreneurial commercial airliner startup in a century * The airliner industry has been taken over by financial types starting in the 1970s, which is one of the reasons why innovation has stalled * Don’t dismiss the thing that you actually want to create for the thing you think you’re good at because what you are good at can change with the right motivation and effort * “We’re just taking a 787, making it long and skinny, changing the wing shape, and putting in more engines.” – Blake Scholl * Very special companies, typically founder-led, are the only companies willing to cannibalize their current business to build for the future * A technically-credible founder, effective storytelling, meaningful partnerships, and top-tier talent are required for a company to succeed * Half of Boom Supersonic’s seed money came from investors that Blake knew from his previous company, and the other half came from investors that were passionate about aviation but thought he was crazy for trying to do this * When in fundraising mode, accomplish milestones that are actually progress, but also ones that look like progress * Tangible, visible, relatable progress is essential for being able to fundraise * Avoid the Bystander Effect, which describes how the more people that are watching a problem, the less likely it is that any one of those people will do something about it * Falling victim to the Bystander Effect prevents society’s most important and obvious problems from being solved

Read the full notes @ podcastnotes.org

More than fifty years after the first Concorde took flight, consumer air travel is actually SLOWER. Blake Scholl and his team at Boom Supersonic are out to reverse this stagnation and change how we think about commercial aviation. In this episode, Mike Maples, Jr of FLOODGATE interviews Scholl to learn more about the history of American aviation, the origins of Boom Supersonic and the challenges it faces now, and how tech founders are exploring unfamiliar spaces with great success.

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Huberman Lab

Recently I had the pleasure of hosting a live event in New York, NY. This event was part of a lecture series called The Brain Body Contract. My favorite part of the evening was the question & answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event in New York, NY.
Thank you to our sponsors
Eight Sleep: https://eightsleep.com/huberman
Momentous: https://www.livemomentous.com/huberman
Social & Website
Instagram: https://www.instagram.com/hubermanlab
Twitter: https://twitter.com/hubermanlab
Facebook: https://www.facebook.com/hubermanlab
TikTok: https://www.tiktok.com/@hubermanlab
LinkedIn: https://www.linkedin.com/in/andrew-huberman
Website: https://hubermanlab.com
Newsletter: https://hubermanlab.com/neural-network
Timestamps
(00:00:00) Introduction
(00:02:17) You've Said Before That Stress Can Be Good for Us. How Do We Know When It's Too Much?
(00:07:44) How Has Hypnosis Been Impacting Your Life?
(00:12:51) What Are the Most Effective Protocols for Boosting the Microbiome?
(00:18:38) Why Do Humans Love/Need Dogs so Much?
(00:23:21) How Can "Night Owls" Best Function in a Society Made For "Morning Birds"
(00:27:04) How Do You See Your Podcast Growing Over the Next Few Years?
(00:31:12) What Is a Stress Inoculation Protocol for Workplace Anxiety?
(00:33:04) What Do You Think Will Be the Next Hot Topic/New Trend in the Field of Neuroscience & Behavioral Therapeutics Within the Next 10-20 Years?
(00:37:53) What Changes Have You Made to Your Fitness Protocol That Include Nutrition That You Wish You Knew Before Starting the Podcast?
(00:40:11) For Things That Take a Long Time — Career, Pursuing a Degree, Etc — Is There a Way to Know Were on the Right Path?
(00:46:36) Conclusion
The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com

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Aarthi and Sriram's Good Time Show✓Claim

Podcast Notes Key Takeaways * Steven Sinofsky doesn’t write immediately when he has an idea; he will stew with an idea for days at a time so he can really think about it * The Darwinian element of early Microsoft was the ability to do email * Microsoft had to realize that TCP/IP was not something it had to make go away, but something that the company would have to pivot around * After getting back from a recruiting trip at Cornell, and only three months on the job as Bill Gates’s technical assistant, Steven wrote a memo explaining why Microsoft had to adopt the “internet thing” * People celebrate the winner for a short time, and then go onto to dislike the winner for a long time * “My whole career at Microsoft I thought we were on the verge of going out of business.” – Steven Sinofsky on only the paranoid survive * The Mac vs PC ads were “brutal”, according to Steven Sinofsky; they were 90% accurate, but the 10% that was inaccurate drove him absolutely bonkers * Have a “Strong opinion, willing to change” operating framework * “Leading is giving people a picture upon which to decide things so that you are not the limiting factor, the gatekeeper, or the micromanager.” – Steven Sinofsky * Leadership requires the fortitude to create the picture for those following you and then let it go * “There is a very fine line between leadership and manipulation.” – Steven Sinofsky

Read the full notes @ podcastnotes.org

This week's special guest is Steven Sinofsky, one of our favorite techno-optimists responsible for shipping Windows and Office products at Microsoft used by billions of people. He is also the author of one of the most popular Substack books - https://hardcoresoftware.learningbyshipping.comIn this episode we talked about Steven's early days at Microsoft, his famous internet memo, working with Bill Gates, and the traits he sees in good leaders and founders, how to set company culture, his experience leading Office and Windows teams at Microsoft, and the secret behind his ability to write well.

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Lenny's Podcast: Product | Growth | Career✓Claim

Podcast Notes Key Takeaways * Having a podcast is a great excuse to talk to someone interesting for an hour * Do not start a podcast if you wouldn’t do it for free in perpetuity * Focus on what excites you and not what you think will move the metrics + Tim Ferriss did a podcast with a person on how to make violins; 80% of his subscribers probably ignored it but 20% reached out to Tim and told him it was their favorite podcast episode of the year * When you’re at a dinner table, what’s the thing that you talk about that causes people to lean in to hear what you have to say? + The answer to this question is what your podcast should be about

Read the full notes @ podcastnotes.org

Chris Hutchins recently left his position as Head of New Product Strategy at Wealthfront to focus full-time on his podcast, All the Hacks.If you’re thinking about starting your own podcast or are simply interested in the process, be sure to check out today’s episode. We dive deep on all things podcasting: the pros and cons, how to climb the charts, and how much time you should expect to spend on each episode from start to finish. We talk in-depth about the process, from pre-production to publication, and share all of the products we use for recording, editing, and publishing. Chris also offers some important tips and tricks on how to get your first subscribers and how to market and grow your podcast, as well as some incredible money-saving hacks that you can start implementing today.

—

Find the full transcript here: https://www.lennyspodcast.com/launching-and-growing-a-podcast-chris-hutchins-all-the-hacks-wealthfront-google/#transcript

—

Thank you to our wonderful sponsors for supporting this podcast:

• Notion—One workspace. Every team: https://www.notion.com/lennyspod

• Vanta—Automate compliance. Simplify security: https://vanta.com/lenny

• Lenny’s Job Board—Hire the best product people. Find the best product gigs: https://www.lennysjobs.com/talent

—

Where to find Chris Hutchins:

• Twitter: https://twitter.com/hutchins

• LinkedIn: https://www.linkedin.com/in/chrishutchins/

• Website: https://chrishutchins.com/

—

Where to find Lenny:

• Newsletter: https://www.lennysnewsletter.com

• Twitter: https://twitter.com/lennysan

• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/

—

Referenced:

• All the Hacks podcast: https://www.allthehacks.com/

• All the Hacks newsletter: https://allthehacks.com/email

• Andy Rachleff on Twitter: https://twitter.com/arachleff

• Kerri Walsh Jennings on All the Hacks: https://www.allthehacks.com/performance-psychology-kerri-walsh-jennings/

• Descript: https://www.descript.com/

• Erika Taught Me podcast: https://podcasts.apple.com/us/podcast/erika-taught-me/id1650076906

• Leigh Rowan on All the Hacks: https://www.allthehacks.com/travel-hacks-leigh-rowan/

• Kevin Kelly’s “1,000 True Fans”: https://kk.org/thetechnium/1000-true-fans/

• Emily Oster’s books: https://emilyoster.net/writing/

• Chris Hutchins on The Kevin Rose Show: https://podcast.kevinrose.com/guests/chris-hutchins/

• Nick Gray’s newsletter: https://nickgray.net/signup-for-email-updates/

• The 2-Hour Cocktail Party: How to Build Big Relationships with Small Gatherings: https://www.amazon.com/2-Hour-Cocktail-Party-Relationships-Gatherings-ebook/dp/B0B2KW6T7J

• MrBeast on YouTube: https://www.youtube.com/channel/UCX6OQ3DkcsbYNE6H8uQQuVA

• Gary Vaynerchuk on Twitter: https://twitter.com/garyvee

• The Danny Miranda Podcast: https://podcasts.apple.com/us/podcast/the-danny-miranda-podcast/id1532160275

• Ray Dalio on Twitter: https://twitter.com/RayDalio

• Danny Miranda’s newsletter on Substack: https://dannymiranda.substack.com/

• ATRX2100 mic bundle on Amazon: https://www.amazon.com/Audio-Technica-ATR2100X-USB-Microphone-Bundle-Filter/dp/B082SYHRY9/r

• Riverside: https://riverside.fm/

• Focusrite Scarlett 2i2 on Amazon: https://www.amazon.com/Focusrite-Scarlett-Audio-Interface-Tools/dp/B07QR73T66

• Sony Alpha 7C mirrorless full-frame camera on Amazon: https://www.amazon.com/Sony-Alpha-Full-Frame-Mirrorless-Camera/dp/B08HVZLQ4F

• Adobe Audition: https://www.adobe.com/products/audition.html

• Pro Tools: https://www.avid.com/pro-tools

• Podpage: https://www.podpage.com/

• Simplecast: https://www.simplecast.com/

• Chartable: https://chartable.com/

• Podstatus: https://podstatus.com/

• Overcast: https://overcast.fm/

• Happy Money: https://www.amazon.com/Happy-Money-Ken-Honda-audiobook/dp/B07MJHJ57T/

• Vagabonding: An Uncommon Guide to the Art of Long-Term World Travel: https://www.amazon.com/Vagabonding-Uncommon-Guide-Long-Term-Travel/dp/0812992180

• Die with Zero: https://www.amazon.com/Die-Zero-Getting-Your-Money/dp/0358099765

• Animal Spirits Podcast: https://podcasts.apple.com/us/podcast/animal-spirits-podcast/id1310192007

• Mythic Quest on AppleTV+: https://tv.apple.com/us/show/mythic-quest

• Unclaimed money: https://www.usa.gov/unclaimed-money

• Savendeals.com: https://www.savendeals.com/

—

In this episode, we cover:

(00:00) Chris’s background

(03:25) Lesson’s from Wealthfront

(09:25) Why storytelling and communication are every bit as important as the product

(11:04) Why you need to understand the user’s experience and keep up with what others are building

(14:56) Why you should focus on overall impact, not just doing what your boss wants

(17:39) Why Chris likes working on big, crazy ideas

(19:10) The early days of Chris’s All the Hacks podcast

(21:34) The pros and cons of starting a podcast

(24:19) The time required to produce an episode

(27:09) How Lenny started his podcast

(28:29) Launch lessons and how Apple rankings work

(30:49) Why you need to create authentic content

(32:57) Be one person’s favorite podcast

(35:01) How Chris ideated and titled All the Hacks

(40:09) How to get started and get your first subscribers

(43:52) How Gary Vaynerchuk used Twitter to establish authority

(45:07) How to take advantage of platforms with built-in growth engines

(47:42) The power of in-person interviews

(48:57) How to pitch to other podcasts

(51:27) Equipment and products for producing podcasts

(57:36) How many downloads it takes in order to be taken seriously

(1:01:28) Using Overcast as a growth lever

(1:09:02) Lightning round

—

Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.

Get full access to Lenny's Newsletter at www.lennysnewsletter.com/subscribe

Vagabonding: An Uncommon Guide to the Art of Long-Term World Travel

Audio-Technica ATR2100X-USB USB/XLR Microphone Bundle with Knox Gear Boom Arm, Shock Mount, and Pop Filter

Happy Money: The Japanese Art of Making Peace with Your Money

Sony Alpha 7C Full-Frame Mirrorless Camera - Black (ILCE7C/B)

Focusrite Scarlett 2i2 3rd Gen USB Audio Interface for Recording, Songwriting, Streaming and Podcasting — High-Fidelity, Studio Quality Recording, and All the Software You Need to Record

Die With Zero: Getting All You Can from Your Money and Your Life

The 2-Hour Cocktail Party: How to Build Big Relationships with Small Gatherings

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Twenty Minute VC

Podcast Notes Key Takeaways * Mailchimp was kind of an accidental business; it was originally built for just a few customers who were struggling to send out email newsletters * The freemium pricing option teleported Mailchimp’s user base from tens of thousand to over a million users within a year of adding it * It is not always better to be faster * It’s okay to be stressed and have chaotic feelings on the inside, but a calm demeanor is important to convey as a leader * “The key to happiness is staying in your lane, and knowing when people need to be in their lane. Don’t get in their lane, and don’t let them get in your lane.” – Ben Chestnut * If you are a “hands-off” leader, ensure that you are also not an “eyes-off” leader * How you are perceived as a leader is often dependent on the setting in which you are leading * Founders tend to conflate their identity with that of their business; but with time, they realize that their life is not their business when they genuinely begin to reflect on their life * Ben is grateful for easing into new levels of wealth over the course of his life instead of having a one-time, shocking liquidity event * The happiest couples have husbands who keep their damn mouth shut * “What I want the most is to not want.” – Ben Chestnut

Read the full notes @ podcastnotes.org

Ben Chestnut is the Co-Founder of Mailchimp, the all-in-one marketing platform for small businesses. Last year, in Sept 2021 it was announced that Intuit would acquire Mailchimp for a reported $12BN. There are so many things to love about the Mailchimp journey to this point. First, Mailchimp was founded as the result of a side project of a design agency Ben and his co-founder, Dan, used to run. Second, Mailchimp is and has always been based in Atalanta, eschewing the notion you have to be in SF or NYC to build a massive business. Then third, they never raised venture funding for the business all the way until their $12BN acquisition. Ben led Mailchimp to over 1,200 employees and millions of global users.

In Today's Episode with Ben Chestnut We Discuss: 1. From Mama's Kitchen to the Smell of Business and Founding Mailchimp:

How did Ben turn a mediocre agency into the founding of Mailchimp? What was the a-ha moment?
At what stage of the business did Ben quit the agency and go all in on Mailchimp? What sign did he need that Mailchimp had true product-market fit?
When Ben's mother died, he bought every flower in the local town to commemorate her. How did Ben's mother impact the type of father and husband he is today? How did she impact the way that he led Mailchimp as CEO?
Ben's fishing trips with his father played a big role in his early years, what were the single biggest lessons for Ben from his fishing trips with his father?
Ben Chestnut: The Leader:
How does Ben define the term "high performance" in leadership?
What does Ben mean when he says "the secret to happiness is to stay in your lane"?
Why would Ben describe himself as the "leader of the misfits"? How did that early experience and labeling impact both the people he hired and the culture he created at Mailchimp?
What does Ben mean when he says he used to have a "hands off, eyes off" leadership style? What have been the single biggest drivers in his development as a leader?
Ben Chestnut: The Person:
Relationship to Money: How does Ben reflect on his relationship to money? How has it changed over time? Why does Ben still to this day buy lottery tickets with his wife?
Conquering Fatherhood: What does being a great father to Ben mean? How does Ben attempt to instil the same work ethic and drive when his children are born into immense wealth?
The secret to Marriage: What does Ben believe is the core to a successful and thriving marriage? How does Ben view his role in the marriage? How has it changed over time?
Potential Lost Identity: A founder's identity is so closely tied to their company, how did Ben manage the challenge of selling his company but retaining his identity? What did Ben learn about himself through many different acquisition processes?
Mailchimp: The Business:
Why did Ben never raise venture money in the 21 year journey of Mailchimp?
Why did Ben never accept any of the acquisition offers that came before Intuit?
How did Ben motivate his team after they knew each acquisition offer was being turned down?
Why did Ben decide the acquisition by Intuit was the right decision for the company?
How does Ben view his role in the company now and moving forward?

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Found My Fitness - Rhonda Patrick

Podcast Notes Key Takeaways * “If I were to pick one activity that’s indispensable, it would be resistance training.” – Dr. Brad Schoenfeld * Aerobic exercise will improve the cardiovascular system but will do little to improve strength, muscle development, bone density, and muscle hypertrophy * Resistance training is an important supplement for reducing calories to lose weight – if you do not lift weights, you will lose muscle as you lose body fat * Adequate protein intake is essential for muscle synthesis and maintenance + Shoot for 1.6-1.8g/kg body weight if resistance training and a minimum 0.8g/kg body weight if sedentary * Combine different concepts and types of training: resistance training, power, cardio, plyometrics * When considering rest periods between sets, the ability to perform volume load is more important than optimizing hormones through rest length * It’s beneficial to give a muscle 48 hours to recover before training again – training sooner won’t blunt hypertrophy because some muscles may not respond well to high training frequency * You can lift lighter loads at higher volumes and still experience gains in muscle but intensity matters! The last few reps need to feel hard * Dosing resistance training: + To maximize hypertrophy: 10-20 sets per muscle, per week + Minimum effective dose to gain muscle: 4 sets per muscle, per week * The most important thing is to be in tune with your body – if you need a day off, take it

Read the full notes @ podcastnotes.org

Dr. Brad Schoenfeld is a professor at Lehman College in the Bronx, in New York City. His research primarily focuses on muscle adaptations to strength training, muscle hypertrophy. Publishing over 300 studies in the field of exercise and sports nutrition as a scientist, Brad began his career as a competitive bodybuilder and personal trainer.

In this episode, we discuss:

05:26 - Why should we lift weights?
06:56 - Why building bone matters
11:33 - How to lift in old age
13:45 - Why to lift while young (especially women)
16:21 - Should children lift weights?
17:05 - Does lifting stunt growth?
19:48 - How to change body composition
27:22 - Protein requirements
29:19 - How to calculate protein needs
36:54 - Protein per meal - what's the right amount?
38:18 - Does time-restricted eating undermine hypertrophy?
43:19 - Anabolic window: myths vs. reality
46:15 - Total daily protein intake
54:49 - Why aging affects muscle power (loss of type II fibers)
57:52 - Power training vs. strength
59:20 - Benefits of explosive power training (fall prevention)
01:03:18 - How to power train with plyometrics
01:03:58 - Training to failure (is it important?)
01:09:59 - Rest in between sets (is it needed?)
01:11:12 - Number of sets per week
01:22:31 - Tips for recovery
01:33:41 - Should you get sore from exercise?
01:36:47 - What can you do for soreness? (without blunting hypertrophy)
01:40:16 - Does aerobic exercise undermine resistance training?
01:44:46 - Resistance training for endurance athletes
01:46:33 - Can stretching increase muscle growth?
01:51:06 - Is yoga a type of resistance training?
01:53:37 - Blood-flow restriction training
01:58:37 - What is Brad's routine?

Watch this episode on YouTube

Show notes are available by clicking here

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Art of Manliness

Once a year, I read The Road by Cormac McCarthy. It's a cathartic annual ritual for me. What is it about this novel that has such an impact on my soul and those of other readers? Who is the man who wrote it, and what was he trying to do with this story of a father and son struggling to survive in a post-apocalyptic landscape?

For answers to these questions, I decided to talk to a foremost expert on McCarthy's work, as well as the literature of the American West in general. His name is Steven Frye and he's a professor of English, a novelist in his own right, and the author and editor of several books about the reclusive, philosophical author, including Understanding Cormac McCarthy. We begin our conversation with some background on McCarthy and a discussion of his distinctive style and themes, and why he avoids the limelight and prefers to hang out with scientists over fellow artists. We then dive into The Road, and Steve unpacks what inspired it, as well as the authors and books that influenced it. We then dig into the big themes of The Road, and how it can be read as a biblical allegory that wrestles with the existence of God. We delve into the tension which exists between the father and son in the book, and what it means to "carry the fire." We end our conversation with why reading The Road makes you feel both depressed and hopeful at the same time.

A spoiler alert here: If you haven't read The Road yet, we do reveal some of the plot points in this discussion. Also, why haven't you read The Road yet?

Resources Related to the Podcast Other books by Steven Frye, including his novel Dogwood Crossing * McCarthy's books mentioned in the show: + The Road + All the Pretty Horses + Blood Meridian + The Orchard Keeper + No Country for Old Men + The Sunset Limited * The film adaptation of The Road * The Santa Fe Institute * Brothers Karamazov* by Fyodor Dostoevsky * "Cat in the Rain" — short story by Ernest Hemingway * "Indian Camp" — short story by Ernest Hemingway * AoM Podcast #635: The Existentialist's Survival Guide * AoM Article: Carry the Fire * AoM Article: Books So Good I've Read Them 2X (Or More!)

Connect With Steven Frye* Steve's website

The Orchard Keeper (Vintage International)

Understanding Cormac McCarthy (Understanding Contemporary American Literature)

Blood Meridian: Or the Evening Redness in the West (Modern Library (Hardcover))

The Brothers Karamazov: A Novel in Four Parts and an Epilogue

The Sunset Limited: A Novel in Dramatic Form

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How Leaders Lead with David Novak✓Claim

Podcast Notes Key Takeaways * Investing is constantly looking at the world as a collection of puzzles, and trying to figure out those puzzles * “I cared about my performance. But what I really cared about was how fast I was learning and how fun the business was.” – Stanley Druckenmiller * The cardinal sin in money management is to getting emotional * “One of the big sins of the Fed is they tend to keep monetary policy too loose for political reasons when the punch bowl should be pulled away.” – Stanley Druckenmiller * Rule number one of being a successful money manager is being overly competitive * Admit that you have had failures, and then go back and analyze those failures so that you can learn from them * Stan is more concerned about a potential crisis happening between 2020 and 2030 now than he has ever been * The current economic conditions are the most “unprecedented cocktail” Druckenmiller has ever been served * Do not invest in the present; imagine how the world is going to be in 18-24 months and invest in that world * Investing principles from Stanley Druckenmiller: + Put all your eggs in one basket and watch it very carefully + If you have an idea, invest quickly and study it later + Examine leading and lagging industries + Be imaginative about what could go wrong (and right) * “That’s the number one lesson I’ve learned. Spend as much time as you can with your children.” – Stanley Druckenmiller

Read the full notes @ podcastnotes.org

Welcome to How Leaders Lead where every week, you get to listen in while I interview some of the VERY best leaders in the world. I break down the key learnings so that by the end of the episode, you’ll have something simple you can apply as you develop into a better leader. That’s what this podcast is all about!
Today’s guest is Stanley Druckenmiller, the #1 investor in the world.
I know, that’s a big claim! But get this: during his 30 years managing money for investors, he had an average annual return of 31%. And he NEVER had a down year. So if you’re even a little interested in finance, you’re going to learn a lot from Stan – including some really practical investment advice and his take on the future of our economy.
But more importantly, there’s a huge leadership lesson to learn. Stan isn’t afraid to envision the future differently than other people. He can see trends and patterns others can’t – and then he has the courage to act on them.
That’s a skill EVERY leader needs to develop. Seeing the future differently allows us to spot opportunities and prepare for what’s coming. If we just go with the flow of what’s current, we’ll always just be a part of the trend, not ahead of it.
You’re about to see for yourself how great leaders aren’t afraid to see the future differently.
So here is my conversation with my good friend, and soon to be yours, Stanley Druckenmiller.

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My First Million

Podcast Notes Key Takeaways * “Strippers know a recession is coming before anybody”– Shaan Puri + Based on the psychology of spending at strip clubs * “Black Friday is like a license-to-spend when you didn’t even need to spend”– Shaan Puri + Sam wants to boycott Black Friday, he hates the idea of buying stuff that you don’t need * Shaan’s three scenarios for how Elon’s Twitter takeover may play out: + 1. Elon makes Twitter more finically viable and everything settles in + 2. Twitter becomes the everything app + 3. Negative snowball effect on Elon’s finances * Continue reading for more detail and to see which scenario Sam thinks is most likely

Read the full notes @ podcastnotes.org

Episode 390: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about Eric Langan and his foray into owning strip clubs, why we should boycott Black Friday, three Twitter scenarios, how to fly on a private jet and much, much more.

Links:
Jettly
r/fatFIRE
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:
(03:20) - Eric Langan
(12:50) - Black Friday
(18:40) - Twitter
(36:10) - George Hotz
(48:10) - Private jets
(53:00) - fatFIRE subreddit

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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My First Million

Podcast Notes Key Takeaways * Paul English has sold six companies, most notably Kayak for $2B, and is currently working on his seventh company * Paul’s internal rate of return is around 30.5% over the last several years across 60 investments * He has some “famous misses”, which include Airbnb, YouTube, Snapchat, and Dropbox * “Team first, customer second, profit third.” – Paul English * Magical teams create magical products, and magical products tend to create profits * After successfully recruiting a talented person, Paul asks them, “Do you know anyone more amazing than you?” * Companies fail because of a founder implosion or because it is trying to solve a problem that no one cares about * “It makes me sad when I see a beautiful product that solves a problem I don’t care about.” – Paul English * Find something that irritates you in your daily life and create a product that resolves that irritation * Paul questions whether a person like Elon (the richest person in the world) should have as much power as he does (control over the world’s richest source of information) * Paul thinks Elon will do something interesting with Twitter, but he’s more interested in all the Twitter replacements that will come out

Read the full notes @ podcastnotes.org

Episode 394: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk with entrepreneur and Kayak co-founder, Paul English (@englishpaulm) about his latest business ideas, his famous missed investments, how to become a strong recruiter, and why he wants to create Twitter's competitor.

Links:
Paul English
Boston Venture Studio
Middle
Bipolar Social Club
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:
(00:25) - switched jobs for a day
(07:05) - who did you know before they met success
(13:45) - become an excellent recruiter
(20:25) - starting a company easier now?
(28:15) - Irritation becomes inspiration
(30:55) - Ideas he's working on
(34:10) - Bipolar disorder

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Modern Wisdom

Podcast Notes Key Takeaways * Nutrition science is built on a house of cards: most are epidemiological observational studies, funding is often biased because nutrition can’t easily be monetized so lacks commercial interest, causality is difficult to parse out, people don’t eat foods in isolation, etc. * Don’t let perfect be the enemy of good: grass-fed, grass-finished is a healthier choice – it’s leaner, higher omega-3s – but conventional beef still provides many benefits such as protein, creatine, vitamins * Precautionary principle: when we don’t have enough data to make a fully informed decision, make a precautionary approach – the nutrition industry has let us down a lot, assume the food is guilty until proven innocent * Worst diet for the brain: highly processed, high in seed oils, no exercise, high in fried foods * Calories in calories out is fundamental to weight loss and weight maintenance but not all calories are created equal – nutrient-dense foods increase satiety and decrease overall consumption + The food industry wants you to focus on calories in calories out because then no food is inherently “bad” or “good” – it’s just your failure if you don’t lose weight * Tips for managing caloric intake: (1) don’t eat while distracted; (2) don’t eat late at night; (3) focus on foods with high nutrient profile; (4) lead with protein; (5) eat enough fiber

Read the full notes @ podcastnotes.org

Max Lugavere is a health and wellness expert, author and a diet advocate.

Working out what to eat is hard. Which is odd because everybody does it. You'd think that the science of nutrition, a thing the entire human race relies on multiple times per day, would have some definitive answers. Thankfully Max can explain why it's such a mess and give some solid principles we can all use.

Expect to learn whether carnivore is an optimal diet for us all to follow, whether organic and non-GMO actually makes that much of a difference, what to look for in a magnesium supplement, the actual science of seed oils, whether sunscreen is a danger, why nutrition science is so contested, why calories matter but they aren't all that matter and much more...

Sponsors:

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Extra Stuff:

Check out Max's website - https://www.maxlugavere.com/

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To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

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Email: https://chriswillx.com/contact/

Genius Foods: Become Smarter, Happier, and More Productive While Protecting Your Brain for Life (Genius Living, 1)

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My First Million

Episode 391: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk about their new favorite AI tool, how to make money from arbitrage, goal setting for 2023, and more.

Links:
Character.AI
Adept
State of AI Report
Vintage Wall Graphics - Etsy
Pipe
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
* Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:
(03:15) - State of AI
(20:00) - Sam & Shaan's 2023 goals
(46:55) - Arbitrage
(01:03:11) - Clapping back on Twitter

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:
• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits
• #209 Gary Vaynerchuk - Why NFTS Are the Future
• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto
* #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett
• #218 - Why You Should Take a Think Week Like Bill Gates
• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More
• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Huberman Lab

Podcast Notes Key Takeaways * Caffeine is not just a stimulant, it’s a strong reinforcer that subconsciously drives behavior – caffeine (tasteless) added to anything will give you a preference for that thing, this applies to behavior, food, company * Caffeine increases dopamine and acetylcholine in the forebrain which improves the ability to think, adjust to mental and physical demands * Caffeine increases the number of dopamine receptors in the reward pathway of the brain * Caffeine acts as an antagonist to adenosine which offsets sleepiness in the first half of the day * Delay caffeine intake 90-120 minutes after waking (unless doing intense exercise) to fight off afternoon sleepiness + Tip #1: If this sounds impossible at first, delay in 15-minute increments until you hit 90 minutes+ + Tip #2: If you can’t wait, drink half of the caffeine when you wake up and the other half a couple of hours later * Does caffeine make you jittery? Consume at least an equal volume of water or electrolyte drink with caffeine to offset * To extract more benefits from caffeine (assuming you already delay intake): (1) Consume on an empty stomach if you can tolerate it; (2) Abstain from caffeine for 2-5 days then resume; (3) Half your amount of caffeine intake for a period of time then resume

Read the full notes @ podcastnotes.org

In this episode, I explain how to use caffeine to enhance mental and physical health and performance, including the optimal dosages and intake schedules for caffeine. I explain how caffeine powerfully reinforces the consumption of certain foods and drinks—thereby increasing how much we like their tastes and seek them out. I discuss the mechanisms by which caffeine increases focus, alertness and mood and reduces sleepiness. I also explain many practical tools for caffeine use, including delaying caffeine intake after waking, intermittent caffeine use, during fasting, before and during exercise, and the use of theanine to curb jitters caused by caffeine. I also discuss the positive effects of caffeine on overall health and longevity and address several myths about caffeine. Since caffeine is one of the most commonly used substances (more than 90% of adults use caffeine daily!), this episode provides actionable tips for adjusting caffeine consumption to positively impact performance and health, including sleep.
Thank you to our sponsors
AG1 (Athletic Greens): https://athleticgreens.com/huberman
Levels: https://levels.link/huberman
Eight Sleep: https://www.eightsleep.com/huberman
ROKA: https://www.roka.com/huberman
InsideTracker: https://www.insidetracker.com/huberman
Supplements from Momentous
https://www.livemomentous.com/huberman
For the full show notes, visit hubermanlab.com
Timestamps
(00:00:00) Caffeine
(00:02:58) Tool: GLP-1, Yerba Mate, Satiety & Weight Loss
(00:11:06) Levels, Eight Sleep, ROKA, Momentous Supplements
(00:15:23) Caffeine Benefits for Mental & Physical Performance
(00:20:23) Caffeine in Nature & Positive Reinforcement
(00:26:44) Caffeine Effects on Brain; Reward Pathways
(00:29:55) Caffeine as a Reinforcing Agent
(00:36:47) AG1 (Athletic Greens)
(00:38:01) Caffeine, Adenosine & Reduced Sleepiness
(00:45:16) Tool: Caffeine Dosage, Caffeine Adapted
(00:53:44) Tool: Delayed Caffeine Intake, Afternoon Crash & Sleep
(01:04:46) Morning Exercise & Residual Caffeine Effects
(01:07:56) Tool: Theanine & Jitteriness; Fasting, Intermittent Caffeine Use
(01:13:00) Theanine: Effects & Dosage
(01:18:41) InsideTracker
(01:19:45) Other Effects: Osteoporosis, Hormone Levels, Depression
(01:27:41) Afternoon Caffeine & Sleep
(01:31:45) Tool: Caffeine & Mental/Physical Performance; Cortisol & Caffeine Abstinence
(01:46:04) Caffeine, Performance & Menstrual Cycle
(01:47:27) Tool: Memory & Caffeine Timing; Adrenaline & Cold Exposure
(01:54:08) Caffeine & Naps
(01:56:34) Tool: Exercise, Caffeine, Dopamine & Positive Reinforcement
(02:01:55) Dopamine Stacking
(02:06:04) Scheduling Caffeine to Maximize Its Effects
(02:08:33) Pro-Health Effects of Caffeine
(02:13:38) Tool: Sugar Cravings & Reinforcing Effects of Caffeine
(02:20:17) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Momentous Supplements, Neural Network Newsletter
Disclaimer
Title Card Photo Credit: Mike Blabac

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Econtalk

Podcast Notes Key Takeaways * According to René Girard, there are two types of desire: physical and metaphysical + Physical desire is a desire for physical utility – that is, what the object can provide us in and of itself + Metaphysical desire is a desire for identity – that is, what the objects say about us * Girard believes that humans desire persistence (wanting our names to last), power, and social reality (recognition, fame, and to be lauded by the social groups we’re in) * Girard believes we fulfill these fundamental desires by making associations with objects by choosing models whom we already think have this heightened being * Girard thinks our fundamental desires – our moral paradigms – are anchored to these models and their associated objects and values * Girard argues that the strength of your desire can’t indicate its authenticity and whether it’s truly yours or not * Girard sees metaphysical desire as the original sin; it is the drive to rival God and his metaphysical splendor * Johnathan believes there are two solutions to metaphysical desires: + Identify that the metaphysical desire is completely perverse and not seek it + Align your physical and metaphysical desires * There is also a negative component to mimesis: the desire to be distant from objects associated with having a deficiency of being * Our sense of being is fundamentally shaped and determined by the cultures we’re in and the models we’re exposed to * Machiavelli saw people as fundamentally egocentric, and that social participation was not the end, but the instrumental means to satisfy appetite and self-preservation * We come to view our social aspect as a way to serve our appetite; we’ve become reduced to these utility-maximizing creatures without consideration of spirit at all * Once our core human ends are satisfied, most economic decision-making comes from the social dimension that is difficult to model with mathematics

Read the full notes @ podcastnotes.org

When the 20-year-old overachiever Johnathan Bi's first startup crashed and burned, he headed to a Zen retreat in the Catskills to "debug himself." He discovered René Girard and his mimetic theory--the idea that imitation is a key and often unconscious driver of human behavior. Listen as entrepreneur and philosopher Bi shares with EconTalk host Russ Roberts what he learned from Girard and Girard's insights into how we meet our primal need for money, fame, and power. The conversation includes the contrasts between economics and Girard's perspective.

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A16z Podcast

Podcast Notes Key Takeaways * It’s important to differentiate between the singular “metaverse” and plural “metaverses” * The metaverse can be an incredibly diverse range of experiences, but Neal understands it to be a singular metaverse with a wide variety of experiences and not multiple metaverses * Games are the closest things we have to metaverse-like experiences, such as Fortnite, Roblox, and Minecraft * Controversy in the gaming-crypto nexus arises from friction between the ideological crypto bros’ desire for interoperability with the game developers’ appreciation for engineering and aesthetics * “We absolutely do not need AR and VR in order to build the metaverse.” – Neal Stephenson * About 5-10% of people experience motion sickness when using state-of-the-art VR; imagine trying to popularize television in the 1950s with the caveat that 5-10% of people will throw up into a waste basket within the first 30 minutes of watching * A good way to think about the metaverse is it as a communications medium, and any communications medium is trying to reach the broadest possible audience * The question of intellectual property when it comes to things like DALL-E is an ethical question that will need to be sorted out eventually * The right of refusal must exist in the metaverse; creators must be able to dictate what their IP can and cannot be used for * People are endlessly creative in both good and bad ways; technology will continue to be used for good and for evil * Neal made his blockchain a proof-of-stake chain because it would have been weird to launch a carbon-intensive chain just after publishing a book centered around climate change * “I think the two most important things are carbon and the polarization of society.” – Neal Stephenson

Read the full notes @ podcastnotes.org

When Neal Stephenson coined “the metaverse” three decades ago, his book Snow Crash was found on the shelves of “science fiction”. While the book remains in that category, many of its concepts are now found in reality…

Fast forward to 2022, where numerous companies are now building toward their version of the metaverse, including Neal himself – working on Lamina1 – a blockchain company oriented toward creators.

While the present metaverses don’t perfectly mimic that from Stephenson’s early imagination, we get the unique opportunity to discuss the various design decisions that he’s making, but also the intersection between the metaverse and gaming, the involvement that AR/VR might play, the evolving role of IP, how artificial intelligence fits in, what he’s building and why, and where he gets all of his ideas from.

Resources:

Neal’s Twitter: https://twitter.com/nealstephenson

Lamina1’s website: https://www.lamina1.com/

Stay Updated:

Find us on Twitter: https://twitter.com/a16z

Find us on LinkedIn: https://www.linkedin.com/company/a16z

Subscribe on your favorite podcast app:https://a16z.simplecast.com/

Follow our host: https://twitter.com/stephsmithio

Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. For more details please see a16z.com/disclosures.

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MInd Pump

Podcast Notes Key Takeaways * Listen to your body!It needs rest and recovery * There is such thing as an unhealthy relationship with exercise – if you notice changes in temperature regulation, appetite, ability to maintain weight, and other hormonal cues, consider changing your activity level * For athletes: in season, the focus is on sports performance, mobility, preventing injury, and low-dose strength training (maybe 1x per week); in the offseason, you can increase strength training if sports training decreases * Training for strength is a better pursuit than training for muscle * Be sure to fuel your body with the protein it needs

Read the full notes @ podcastnotes.org

In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom.

Mind Pump Fit Tip: The goal should ALWAYS be to do the least amount of work to elicit the most amount of change. (2:09)
Why the guys are SO excited about Organifi’s Peak Power release. (8:53)
VR, the ultimate party trick? (15:03)
Avalanches are scary. (26:37)
Mind Pump Recommends, Orgasm Inc. on Netflix. (31:53)
SleepMe during pregnancy is a game changer. (43:29)
ListenerLive question #1 – What program do you recommend transitioning from bodybuilding to powerlifting? (46:27)
ListenerLive question #2 - What sort of training and movements would you suggest as I continue this mobility journey in pursuit to get back into playing sports? (55:36)
ListenerLive question #3 - How, if any, can you marry aesthetic, performance, and strength for a dancer? (1:06:47)
ListenerLive question #4 - What is the best way to gain a lot of needed weight while also keeping my physique in check? (1:21:23)

Related Links/Products Mentioned

Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com
MIND PUMP LIVE Q&A W/ MAX LUGAVERE
BLACK FRIDAY SPECIAL: ALL MAPS Fitness Products & Bundles 60% off! Promo code BLACKFRIDAY at checkout (Code expires Sunday Nov. 27th)
Visit Organifi for the exclusive offer for Mind Pump listeners! Promo code MINDPUMP at checkout
Visit SleepMe for an exclusive offer for Mind Pump listeners!
Mind Pump #1945: How To Formulate A Supplement That Works With Shanais Pelka
Oculus Founder Claims To Make VR Headset That Will Actually Kill You If You Die In A Game
Watch Aftershock: Everest and the Nepal Earthquake | Netflix
Watch Avalanche | Netflix
Watch Orgasm Inc: The Story of OneTaste | Netflix
Mind Pump #1927: Performance Training Secrets From A Top NBA Trainer With Cory Schlesinger
Mind Pump Podcast – YouTube
Mind Pump Free Resources

People Mentioned

Cory Schlesinger (@schlesstrength) Instagram

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Huberman Lab

Podcast Notes Key Takeaways * Nutrition and mental health interact intimately and even causally in some cases * Processed foods rich in fat, carbohydrates, and sugar are the worst for metabolic health and mental health * Insulin resistance is impaired in people with chronic mental disorders * A ketogenic diet has shown beneficial effects in the treatment of chronic depression, PTSD, Alzheimer’s, alcohol use disorder, bipolar disorder, schizophrenia, epilepsy * The beauty of the ketogenic diet for intervention is you can measure with objective biomarkers * “Once you understand the science of mitochondria, you can actually connect all the dots of the mental health puzzle.” – Dr. Chris Palmer * Calorie restriction, ketogenic diet, and carbohydrate restriction are inducing metabolic changes in the brain and body that can be beneficial to brain health – it’s not just about villainizing sugar or carbohydrates alone * Just like medication, dose the diet: for some people, symptoms can be reduced without fully being on a ketogenic diet; just cutting highly processed foods rich in carbohydrates, fat, and sugar is sufficient * The obesity epidemic is really a mystery though we want to believe it’s diet; it’s not as simple as energy balance or food – we had junk food and highly processed diets in the 70s – it’s likely mitochondrial health deficits + Sleep disruption, stress, trauma, drug and alcohol use, tobacco, and THC impair mitochondria and mitochondrial dysfunction * “I see obesity as a symptom of metabolic derangement in the body or brain…and if we’re really going to get anywhere we need to identify what is causing metabolic derangement.” – Dr. Chris Palmer * Exogenous ketones or supplementing with ketones while on a standard diet isn’t enough + The ketogenic diet isn’t just about ketones, people on the diet are also lowering glucose levels, improving insulin signaling, ramping up mitochondrial biogenesis (particularly in the liver), gut microbiome changes, hormones are repaired, etc.

Read the full notes @ podcastnotes.org

My guest this episode is Chris Palmer, M.D., a board-certified psychiatrist and assistant professor of psychiatry at Harvard Medical School. He explains the important connection between nutrition, metabolism and mental health and his pioneering work using the ketogenic diet to successfully treat patients with various mental illnesses, including depression and schizophrenia. Dr. Palmer explains how the ketogenic diet is an evidenced-based treatment for epilepsy, mimics the fasted state and can offset the cognitive decline in Alzheimer’s. He describes the key roles of mitochondria in mental health, how certain conditions likely arise from mitochondrial dysfunction, and how low-carbohydrate diets increase mitochondrial turnover to improve mental health. He also explains how low-carbohydrate diets positively impact the gut microbiome and weight loss, important risk factors for mitochondrial health such as marijuana and alcohol, and the best way to increase circulating ketones depending on individual needs. We also cover how a ketogenic diet impacts mood, sleep, and fertility. Dr. Palmer’s work stands as a revolutionary approach to mental health and disease that, given the prevalence of mental health challenges, should be of interest to people of all backgrounds and ages.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

Eight Sleep: https://www.eightsleep.com/huberman

ROKA: https://www.roka.com/huberman

InsideTracker: https://www.insidetracker.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Chris Palmer, Mental Health & Metabolic Disorders

(00:03:25) Thesis, Eight Sleep, ROKA

(00:07:18) Nutrition & Mental Health

(00:20:43) Low-Carb Diets & Anti-Depression, Fasting, Ketosis

(00:27:52) Schizophrenia, Depression & Ketogenic Diet

(00:34:32) AG1 (Athletic Greens)

(00:35:38) Psychiatric Mediations, Diet Adherence

(00:42:35) Highly Processed Foods, Ketones & Mental Health Benefits

(00:46:51) Ketogenic Diet & Epilepsy Treatment

(00:56:10) Ketogenic Diet & Mitochondria Health

(00:57:05) Nutrition & Benefits for Neurologic/Psychiatric Disorders

(01:05:44) Mitochondrial Function & Mental Health

(01:15:12) InsideTracker

(01:16:23) Mitophagy, Mitochondrial Dysfunction, Aging & Diet

(01:25:09) Neurons, Mitochondria & Blood Glucose

(01:31:54) Obesity, Ketogenic Diet & Mitochondria

(01:40:00) Mitochondrial Function: Inheritance, Risk Factors, Marijuana

(01:46:34) Alcohol & Ketogenic Diet

(01:55:21) Brain Imaging, Alzheimer’s Disease & Ketones

(02:01:05) Exogenous (Liquid) Ketones vs. Ketogenic Diet

(02:06:27) Neuronal Damage, Ketones & Glucose

(02:10:16) Alzheimer’s Disease, Age-Related Cognitive Decline & Ketogenic Diet

(02:23:45) Ketogenic Diet & Weight Loss

(02:35:47) Ketogenic Diet & Fasting, Hypomania, Sleep

(02:46:37) Low Carbohydrate Diets, Menstrual Cycles, Fertility

(02:52:23) Obesity Epidemic, Semaglutide & GLP-1 Medications

(03:01:01) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Social Media

Disclaimer

Title Card Photo Credit: Mike Blabac

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My First Million

Podcast Notes Key Takeaways * Check out My First Million’s Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Episode 388: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk to Bryan Johnson (@bryan_johnson) about starting Braintree - which he sold for hundreds of millions - and is his current businesses as Founder/CEO of Kernel and his own personal project Blueprint, where he's working to reduce his biological age.

Links:

Braintree
Kernel
Blueprint
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(03:25) - Background starting w/Braintree

(15:30) - Financial plans and life changes

(21:45) - Where do you put your money

(27:05) - What does Kernel do

(36:55) - Blueprint blog

(57:40) - Goal alignment

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Infinite Loops

Podcast Notes Key Takeaways * Check out the Infinite Loops Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

“With enough curiosity, self-confidence is irrelevant.”

Tinkered Thinking is a writer, artist, author and creator. He is also the worthy winner of our ‘White Mirror’ competition.

His writing includes a series of ‘Lucilius Parables’, short stories dispersed throughout time and space designed to help readers reconceptualise their experience of being alive.

He joined the show to discuss writing, technology, curiosity, optimism and MUCH more!

Important Links:

Website
Twitter
The Lucilius Parables, Volume I
The Lucilius Parables, Volume II
The Century of the Self: Happiness Machines - Adam Curtis

Show Notes:

The origin of Lucilius
Why write short stories?
Fear and human nature
Technology, progress and optimism
Where is the positive poetry of today?
The momentum metric
How to rebrand Guatemala
White Mirror
Choose your disposition
The power of curiosity
The question as a concept
Hope grows foolish with no doing

Books Mentioned:

The Lucilius Parables, Volume I; by Tinkered Thinking
The Lucilius Parables, Volume II; by Tinkered Thinking
The Elegant Universe: Superstrings, Hidden Dimensions, and the Quest for the Ultimate Theory; by Brian Greene
The Fifth Science; by Exurb1a
Foundation; by Isaac Asimov
Zen and the Art of Motorcycle Maintenance; by Bob Pirsig
The Beginning of Infinity; by David Deutsch
Language in Thought and Action; by S.I. Hayakawa
Screw the Zoo: Escape From Your Cage, Free Your Mind, and Take Over the World; by Sam McRoberts
Unflattening; by Nick Sousanis
Atomic Habits; by James Clear
The Power of Habit; by Charles Duhigg
The Hitchhiker's Guide to the Galaxy; by Douglas Adams
The Egg; by Andy Weir
The Varieties of Religious Experience by William James
Awakening: Conversations with the Masters; by Anthony De Mello
Spiritually Incorrect Enlightenment; by Jed McKenna

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Nudge - Marketing Science Simplified✓Claim

Podcast Notes Intro * Nudge podcast host, Phil Agnew (@p_agnew), explains the ancient storytelling technique he used to make viewers 82% more likely to follow his TikTok

Read the full notes @ podcastnotes.org

Today’s title sounds like clickbait, but that’s the point. In this show, I share the history of clickbait, why curiosity can make someone seem more attractive, the science behind memory, and how I got 11k followers on TikTok in just two weeks.

Listen to the episode “How I made a Reddit ad 15% more effective”: bit.ly/3E8jpYR

The data behind the TikToks: https://bit.ly/3vd5QUg

Robert Cialdini’s Pre-Suasion: https://amzn.to/3OvEYFB

Sign up for my newsletter: https://www.nudgepodcast.com/mailing-list

Try HubSpot for free: https://hubspot.sjv.io/jWq4k6

Pre-Suasion: A Revolutionary Way to Influence and Persuade

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Modern Wisdom

Mark Bell is a world record-breaking powerlifter, owner of Super Training Gym and inventor of the Sling Shot.

A lack of support killed more dreams than a lack of competence ever did. There's a modern trend that trying hard at things and taking them seriously is uncool. Disincentivising excellence is one of the worst habits a society can have and it's time to put a stop to it.

Expect to learn why taking a compliment is a skill that many of us don't have, why there is no growth without having a goal you're working toward, why Mark has never had a bad day, what it was like to train under the legendary Louie Simmons at Westside Barbell, how crucial the story you tell yourself about life is and much more...

Sponsors:

Get 20% discount on House Of Macadamias’ nuts at https://houseofmacadamias.com/modernwisdom (use code MW20)

Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied)

Get a Free Sample Pack of all LMNT Flavours at https://www.drinklmnt.com/modernwisdom (discount automatically applied)

Extra Stuff:

Check out Mark's website - https://markbellslingshot.com/

Subscribe to Mark's YouTube Channel - https://www.youtube.com/c/MarkBellsPowerProject

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Knowledge Project

Podcast Notes Key Takeaways * Check out The Knowledge Project Episode Page & Show Notes

Read the full notes @ podcastnotes.org

This episode is packed with wisdom from previous guests on the art of making better decisions.

We discuss the three types of decision-makers, how to control your emotions when making decisions, why it’s crucial to look at every decision differently, the processes for coming to the right decision, and how to learn from your mistakes when you get it wrong.

The guests on this episode are author Ventakesh Rao (Episode 7), psychologist, author and professional poker player Maria Konnikova (Episode 89), Stripe co-founder Patrick Collison (Episode 32), cognitive-behavioral decision science author and professional poker player Annie Duke (Episode 37), and Shopify co-founder Tobi Lutke (Episode 41). Transcript: https://fs.blog/knowledge-project-podcast-transcripts/tkp-insights-decision-making/ --

Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday, our Brain Food newsletter shares timeless insights and ideas you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * Racism is attributing some characteristic to an entire population based on the notion that some members of that population are doing bad things * “The great lie that we tell ourselves is that people who are evil are not like us, they’re a class apart. People who do evil things, people who support evil people, they’re not like us.” – Ben Shapiro * The polarization of politics increases the likelihood of normal people supporting an evil person in order to stop someone they believe to be more evil * “Politics is Veep, it is not House of Cards.” – Ben Shapiro + Everyone in politics is an idiot until proven otherwise; virtually everything is done out of stupidity rather than malice * If we remove agency from individuals, and if we blame broad-scale political rhetoric for every act of violence, then the people who pay the actual price will be the general population because free speech will go away * Elon Musk taking over Twitter threatens the state’s control over what can be said on the platform * The town square is online; banning people from the town square is un-personing them, and in American society, a person should not be unpersoned unless they have violated a criminal statute * Joe Biden allows the prevailing winds of his party to carry him to incredibly radical places, and then he doubles down on the radicalism in disingenuous ways * The coordinated, collusive media blackout to cut off the lifecycle of the Hunter Biden laptop story before relevant questions could be answered is a bigger story than the laptop story itself * The West took the worst possible view on the Russian-Ukraine issue before the conflict ever broke out: it encouraged Ukraine to join NATO and the EU without actually letting it join, while simultaneously provoking Russia in the process * There is a bizarre focus on throwing hundreds of billions of dollars in subsidies at the same three “renewable energy” technologies that aren’t viable solutions to climate change * “Nuclear energy is great. Nuclear energy is a proven source of energy and we should be radically extending the use of nuclear energy.” – Ben Shapiro * The meaning of life is to fulfill what God made you do across a series of roles * Most good people die, are mourned by their family and friends, and are forgotten in two generations; they are the people who incrementally move the ball forward in the world, oftentimes more so than the people that are considered great

Read the full notes @ podcastnotes.org

Ben Shapiro is a conservative political commentator, host of The Ben Shapiro Show, co-founder of The Daily Wire, and author of The Authoritarian Moment and other books. Please support this podcast by checking out our sponsors: – ExpressVPN: https://expressvpn.com/lexpod to get 3 months free – Policygenius: https://www.policygenius.com/ – BetterHelp: https://betterhelp.com/lex to get 10% off – InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Ben’s Twitter: https://twitter.com/benshapiro Ben’s Instagram: https://instagram.com/officialbenshapiro Daily Wire: https://dailywire.com Ben’s Books: The Authoritarian Moment: https://amzn.to/3T3RRJv Facts (Still) Don’t Care About Your Feelings: https://amzn.to/3T3Hwgs How to Destroy America in Three Easy Steps: https://amzn.to/3fxmeKx The Right Side of History:

How to Destroy America in Three Easy Steps

The Authoritarian Moment: How the Left Weaponized America's Institutions Against Dissent

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HBR IdeaCast ✓

Claim

Podcast Notes Key Takeaways * Megathreats are serious threats that are not only economic and financial, but social, political, environmental, technological, etc., and they are all interconnected * Global public debt to GDP was 100% in the 1970s, 200% in the 2000s, and 350% in 2021; these debt-to-GDP ratios are unsustainable * Public debt builds up because every time there is a problem, we choose to steal growth from the future instead of experience pain in the present * Zombie entities can survive when interest rates are near zero because the cost to service their debt is low; however, it becomes much more difficult to service debt when interest rates must increase to fight inflation * Climate change affects energy prices; criminalizing the use of fossil fuels has led to underinvestment in the fossil fuel industry * The increased investment in the renewable energy industry is not sufficient to compensate for the underinvestment in the fossil fuel industry * The US has weaponized the dollar around the world, which may result in it not being the global reserve currency for much longer * Central banks are in a debt trap: they have to raise interest rates to combat rising inflation, but they cannot raise interest rates too high or for too long without risking an economic and financial crisis because of the all-time high levels of debt * Today, we have the worst of the 1970s and the worst of the post-Great Financial Crisis (GFC) period: debt levels are at all-time highs and there are stagflationary supply shocks * We know that having a tight fiscal and monetary policy is needed to fight inflation, but there is so much debt in the system that central banks will be forced to pivot back to inflationary monetary policies to service the debt * There will be a backlash against the private sector if the government doesn’t provide a sufficient amount of goods and services for those that have been left behind * “Eventually, we need to have another major burst of technological innovation that increases productivity growth in order to start to address these problems in a more cooperative way.” – Nouriel Roubini * Companies, countries, and sovereigns are incentivized to act in their own self-interest, and not necessarily in the self-interest of the rest of the world * “The only way to survive a storm is to build a shield. And the shield has to be collective, rather than individual.” – Nouriel Roubini

Read the full notes @ podcastnotes.org

Nouriel Roubini, professor emeritus at NYU’s Stern School of Business, says that a confluence of trends – from skyrocketing public and private debt and bad monetary policies to demographic shifts and the rise of AI – are pushing the world toward catastrophe. He warns of those interconnected threats, but also has suggestions for how political and business leaders can prepare for and navigate through these challenges. He draws on decades of economic research as well as his experience accurately predicting, advising on, and observing responses to the 2008 global financial crisis, and he's the author of "Megathreats: Ten Dangerous Trends that Imperil our Future, and How to Survive Them.”

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Nudge - Marketing Science Simplified✓Claim

Podcast Notes Key Takeaways * Julius Caesar used costly signaling to win the hearts and minds of his people * Costly signaling describes how the meaning and significance we attach to something is felt in direct proportion to the expense with which it is communicated * Once captured by pirates and held for ransom, Julius Caesar demanded the pirates increase his ransom to be freed, knowing that placing a higher ransom on his head would increase his perceived worth and grow his influence back in Rome * Julius Caesar was willing to do costly things that other generals weren’t willing to do: + Went into massive debt to throw extravagant public parties + Forgoed the acceptance of significant awards + Memorized all of his soldier’s names + Ate the same food his soldiers ate + Slept outside in the freezing cold with his soldiers + Paid his soldiers more than anyone else and got them better armor

Read the full notes @ podcastnotes.org

Julius Caesar is considered by most historians the greatest military commander of all time. You might know of his war strategies, battle tactics, and perhaps his career history. But I bet you don’t know how he convinced a continent’s population to follow him. Or how he made the region’s largest army adore him. In this episode, you’ll learn the leadership tactics that took Julius Caesar to the top. You’ll hear the methods he used to convince and influence others. You’ll discover applicable practices that you can use, and you’ll even hear the real reason why the humble potato is so popular.

Try HubSpot for free: https://hubspot.sjv.io/jWq4k6

How To Take Over The World (Julius Caesar): https://bit.ly/3MPXkC8

My costly signalling experiment: https://i.im.ge/2022/10/21/2Nj6C0.Costly-Signal.png

Listen to episode 63: https://bit.ly/3TnCKeN

Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list

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Huberman Lab

Podcast Notes * You generally have two 90-minute periods of intense blocks of focus: one period in the morning and one period in the afternoon – * Tip: To find the right 90-minute time windows for you, pay attention to peak physical and mental energy and set a stopwatch to get about 60 minutes of focus (you will take some time to ease in) * Remember, rewiring of neurons happens during deep sleep and non-sleep deep rest

Read the full notes @ podcastnotes.org

Welcome to a sneak peek of the first Ask Me Anything (AMA) episode, part of Huberman Lab Premium.

The Huberman Lab Premium subscription was launched for two main reasons. First, it was launched in order to raise support for the standard Huberman Lab podcast channel — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation.

Want your question answered? Subscribe to Huberman Lab Premium at https://hubermanlab.com/premium

Timestamps

(00:00:00) Introduction

(00:01:09) How do you use ultradian cycles in your daily work? [Jackson Lipfert]

(00:22:38) Huberman Lab Premium

In the full AMA episode, we discuss:

Neuroplasticity and dementias (Alzheimer's, MS, Parkinson's) — Protocols for protecting the brain?

Zone 2 training

What do you do when you live in a northern climate and the sun doesn't rise until hours after you are up?

Morning routine for people who work from 8 am to 5 pm

Best productivity method: to-do list or time-blocking everything on a calendar?

Seed oils and metabolic disease

Do recommendations and protocols you give change with age (beyond 60)?

What advice would you give to your younger self?

Social & Website

Instagram: https://www.instagram.com/hubermanlab

Twitter: https://twitter.com/hubermanlab

Facebook: https://www.facebook.com/hubermanlab

TikTok: https://www.tiktok.com/@hubermanlab

LinkedIn: https://www.linkedin.com/in/andrew-huberman

Website: https://hubermanlab.com

Newsletter: https://hubermanlab.com/neural-network

Huberman Lab is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

Title Card Photo Credit: Mike Blabac

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Huberman Lab

Podcast Notes * Food has to be broken down and systematically put into forms the body can use for energy * Exercise is the hack – “Exercise is the only thing you can do to actually improve your biomarkers of health without even losing weight.” – Dr. Layne Norton * Creating a new identity: people don’t just eat because they’re hungry – there are major social and psychological elements to eating that need to be addressed when becoming healthier; in extremes, you may need a new community * The best diet is the one you can stick to forever – pick the form of restriction that feels least restrictive to you – this could be time-restricted or calorie restricted * What we know about gut health: (1) more diversity is better; (2) soluble fiber is positive and acts as a prebiotic; (3) prebiotics work better than probiotics; (4) some evidence that saturated fat is not good for microbiota (this theory is in its infancy); (5) exercise * Protein is the biggest lever you can pull for lean body mass – try making small changes to increase protein to existing meals and reach your daily goal (~1.6g-2.6g/kg body weight)

Read the full notes @ podcastnotes.org

My guest is Layne Norton, Ph.D. — one of the world’s foremost experts in nutrition, protein metabolism, muscle gain and fat loss. We discuss the science of energy utilization and balance, the efficacy of different diets (e.g., ketogenic, vegan, vegetarian, carnivore, omnivore), and how best to build lean muscle mass and lose fat. We also discuss optimal protein and fiber intake, the best sources of protein, the correlation between appetite, satiety signals and exercise, along with male and female-specific needs. Dr. Norton also explains how to support a healthy gut microbiome and offers insight into sugar and artificial sweeteners, processed, cooked, and raw foods, supplements, seed oils, and the relationship of LDL/HDL levels to cardiovascular health. This episode serves as a master class in nutrition, metabolism and exercise and is sure to benefit people of all ages and with different health and fitness goals.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

LMNT: https://www.drinklmnt.com/huberman

ROKA: https://www.roka.com/huberman

InsideTracker: https://www.insidetracker.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

Huberman Lab Premium

https://hubermanlab.com/premium

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Layne Norton, Nutrition & Fitness

(00:02:53) LMNT, ROKA, InsideTracker, Momentous

(00:06:50) Calories & Cellular Energy Production

(00:12:35) Energy Balance, Food Labels, Fiber

(00:15:19) Resting Metabolic Rate, Thermic Effect of Food

(00:19:04) Exercise & Non-Exercise Activity Thermogenesis (NEAT)

(00:25:49) Losing Weight, Tracking Calories, Daily Weighing

(00:29:24) Post-Exercise Metabolic Rate, Appetite

(00:35:04) AG1 (Athletic Greens)

(00:36:19) Exercise & Appetite, Calorie Trackers, Placebo Effects & Beliefs

(00:43:46) Exercise & Satiety Signals, Maintain Weight Loss & Identity

(00:56:32) Weight Loss & Maintenance, Diet Adherence

(01:03:33) Restrictive Diets & Transition Periods

(01:08:03) Gut Health & Appetite

(01:16:23) Tool: Supporting Gut Health, Fiber & Longevity

(01:23:59) LDL, HDL & Cardiovascular Disease

(01:30:31) Leucine, mTOR & Protein Synthesis

(01:37:31) Tool: Daily Protein Intake & Muscle Mass

(01:44:24) Protein & Fasting, Lean Body Mass

(01:55:38) Plant-Based Proteins: Whey, Soy, Leucine, Corn, Pea

(02:04:28) Processed Foods

(02:11:54) Obesity Epidemic, Calorie Intake & Energy Output

(02:17:33) Obesity, Sugar & Fiber, Restriction & Craving

(02:25:57) Artificial Sweeteners & Blood Sugar

(02:38:55) Artificial Sweeteners & Gut Microbiome, Sucralose, Blood Sugar

(02:50:19) Rapid Weight Loss, Satiety & Beliefs

(02:58:13) Seed Oils & Obesity, Saturated Fat, Overall Energy Toxicity

(03:08:15) Females, Diet, Exercise & Menstrual Cycles

(03:14:05) Raw vs. Cooked Foods

(03:16:32) Berberine & Glucose Scavenging

(03:19:12) Fiber & Gastric Emptying Time

(03:21:00) Supplements, Creatine Monohydrate, Rhodiola Rosea

(03:30:33) Hard Training; Challenge & Mental Resilience

(03:36:12) Carbon App

(03:47:11) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Neural Network Newsletter, Social Media

Disclaimer: https://hubermanlab.com/disclaimer

Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com

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Deep Questions with Cal Newport ✓

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Podcast Notes Key Takeaways * There are two types of ambition: Type 1 ambition and Type 2 ambition + Type 1 ambition craves activity and feasts at the buffet of appealing opportunities that success creates + Type 2 ambition craves simplicity and autonomy, and sees success as a source of leverage to reduce stressful obligations * Know where you fall on the spectrum of type 1 and type 2 ambition so you are better prepared to handle success when it comes * The First Control Trap: trying to get a lot of autonomy in your career before you’ve built up the skills to justify it * The Second Control Trap: after getting enough leverage, skills, and power in your professional marketplace, it is hardest to gain more autonomy because there is a lot of pressure to stay in your position and get a higher salary, more prestige, etc. * Positively approach your manager: frame your request in a way that explains how it will improve the company instead of only explaining how it will make your life better * Having an audience that can directly respond to your work creates a deliberate practice effect that will motivate you to publish your best work * Writing to a private journal may increase your productivity, but there is no feedback function from an audience that cares * How to build community: write, text, or call someone you care about each day; join and contribute to an online community daily; create a daily tradition with a partner * It is optimal to plan how you spend your time on multiple different time scales + Plan concise daily, weekly, and quarterly plans with less detail as the time scale increases * Cal chooses the books he reads for functional reasons (needed for research) and for inspirational reasons (appears to be interesting) * Cal stops drinking coffee after 1:30 PM to prevent the caffeine from affecting his sleep * Advice for young people that want to live a deep life: + Do not get too specific about what profession you want to do too early + Be 10x more intentional about your academic work than everyone you know + Introduce some sort of physical and mental discipline into your life + Expose yourself to bulk, positive randomness and embrace the failed simulation effect + Study character and leadership + Serve people, and make that the throughline to each of your pursuits * Be the person that is weird about not using their phone

Read the full notes @ podcastnotes.org

Get your questions answered by Cal! Here’s the link: bit.ly/3U3sTvo

DEEP DIVE: The Two Types of Ambition [4:36]

LIVE CALL: Escaping the “Second Control Tap” [28:10]
Can journaling make me a better writer? [53:26]
What’s an example of a keystone habit for building community? [56:03]
Can Cal give an example of a quarterly plan? [1:00:00]
How does Cal choose what books to read? [1:06:16]
What’s is Cal’s philosophy on caffeine? [1:15:12]
How can a teenager prepare to live deeply? [1:20:59]

Thanks to our Sponsors:

givingwhatwecan.org/deep
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Thanks to Jesse Miller for production, Jay Kerstens for the intro music, and Mark Miles for mastering.

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Art of Manliness

Podcast Notes Key Takeaways * Check Out the Art Of Manliness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

The Twilight Zone is arguably one of the best and most influential shows in television history. The reason it endures, and is still being watched and talked about more than sixty years after its debut, can not only be traced to its superior storytelling and innovations in the genres of horror, science fiction, and fantasy, but the fact that each episode is embedded with a lesson on how to grapple with life's moral and existential dilemmas.

Here to unpack those life lessons is Mark Dawidziak, author of Everything I Need to Know I Learned in the Twilight Zone. Today on the show, Mark and I discuss the parable-like morals from a selection of Twilight Zone episodes, drawn from those that are my favorites, Mark's favorites, and simply classic. And, since Halloween is coming up, Mark and I both offer our picks for the just plain scariest episodes to watch.

Resources Related to the Episode Episodes referenced in the show: + "A Stop at Willoughby" + "Walking Distance" + "Time Enough at Last" + "A Nice Place to Visit" + "To Serve Man" + "Mr. Bevis" + "Kick the Can" + "The Monsters Are Due on Maple Street" + "The Obsolete Man" * Mark's picks for the scariest Twilight Zone episodes: + "Twenty Two" + "Ring-a-Ding Girl" * Brett's picks for the scariest Twilight Zone episodes: + "Living Doll" + "The Dummy" + "It's a Good Life" * AoM articles inspired by Twilight Zone* episodes: + Can’t Have the Sweet Without the Bitter (Inspired by "A Nice Place to Visit") + How Redundancies Increase Your Antifragility (Inspired by "Time Enough at Last") + Sunday Firesides: Things Don’t Get Old, We Do (The illustration is an Easter egg homage to "Walking Distance")

Connect With Mark Dawidziak* Mark's Website

Everything I Need to Know I Learned in the Twilight Zone: A Fifth-Dimension Guide to Life

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Creative Codex ✓

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In 1948, Salvador Dali wrote a notorious treatise with the intention to "save modern art from chaos and laziness". On this feature length episode, we explore Salvador Dali's 50 Secrets of Magic Craftsmanship.

We focus on ten essential secrets from this bizarre treatise including: the secret of the painter's pointed mustache, the sleep technique known as the 'slumber with a key', rules for lovemaking, the secret of having a spider as a pet, pigments to rely on and those to banish from your palette, and many more! So did he succeed in saving modern art with Dalinian magic? Let’s find out!

Learn more about Salvador Dali's artwork and life in episode 7 of Creative Codex. To listen: scroll down in the podcast feed to '7: Salvador Dali (Saint of Delusion)'.

If you are enjoying the show and would like to leave a tip, you can now do so on Venmo! Just open your Venmo app and search: @creativecodex

If you would like to become a patron of the show and receive access to all the patron-exclusive Creativity Tip episodes, head over to: https://www.patreon.com/mjdorian

All music in this show is written and produced by MJDorian.

Creative Codex is written & produced by MJDorian

https://mjdorian.com/

Follow my art, music, and updates on Instagram, where you'll also find my email: https://www.instagram.com/mjdorian/

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The Danny Miranda Podcast

Podcast Notes Key Takeaways * All else being equal, the person who knows how to write a good cold email will be exponentially more successful than the person who doesn’t * Networking is not just about getting contact information; it’s figuring out how to help the person you connect with * Spend time with people that give you energy when you are around them * Put yourself in a position where you are excited about what you are doing * Persistence is required for success; you will eventually figure it out if you stay at it long enough * Think of the brand you are creating as a person, and brainstorm where this person would hang out, what platform they would use, who they would interact with online, etc. * Nik believes there will one day be a “Feastables Mafia” like there is a PayPal Mafia today

Read the full notes @ podcastnotes.org

Nik Sharma is a brand builder. He's the creator of Sharma Brands (a marketing agency that's worked with MrBeast and Emma Chamberlain). In this conversation, we spoke about not going to college, how he's used Twitter effectively, the two skills everyone should learn if they're about to graduate college, and how he got in contact with Mark Cuban via cold email.

(0:00) Bob The Builder

(2:16) Nik’s Childhood Teacher

(6:39) Skills To Learn

(9:49) Mark Cuban Email

(13:45) Vibes

(14:40) David Perell Friendship

(16:08) Saving Cousin’s Life

(18:49) Death

(21:11) Building A Brand

(26:55) Working With MrBeast

(33:30) Working With Emma Chamberlain

(37:04) Small Inflection Points

(40:45) Not Going To College

(47:00) Gary Vaynerchuk

(49:55) Scaling Sharma Brands

(53:39) Twitter

(59:20) Challenge

Nik's Links

Twitter: https://twitter.com/mrsharma

Cold Email Thread: https://twitter.com/mrsharma/status/1463205121979002890

My Links

✉️ Newsletter: https://dannymiranda.substack.com

🎙 Podcast: https://anchor.fm/dannymiranda

🎥 YouTube: https://youtube.com/dannymiranda

🐣 Twitter: https://twitter.com/heydannymiranda

📸 Instagram: https://instagram.com/heydannymiranda

🕺 TikTok: https://tiktok.com/@heydannymiranda

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Huberman Lab

Podcast Notes * In the 1960s and 1970s, meditation and psychedelic use were talked about as one in the same practice * To get better at falling asleep or manage lost sleep, try yoga nidra or non-sleep deep rest at some point during the day * If your goal is to increase focus, and mood, and deliberately control shifts in interoception/exteroception, traditional meditation is beneficial * A wandering mind is an unhappy mind: what people are thinking at any given moment is a better predictor of happiness than what people are doing – being fully engaged in what you’re doing is the strongest predictor of happiness * Choosing the right meditation for the moment: test whether you are in an interoceptive or exteroceptive state; then, choose the meditation that allows you to go against the grain of your natural state to train your body, brain, and increased neural plasticity for trait changes * Meditation tip: instead of dwelling on your ability to remain focused, think about your ability to refocus – that’s where the training and magic happens * Key question to ask before meditation: do you want to be more relaxed or more alert through the meditation practice * How long should you meditate? Just like exercise, the best form of meditation is the one you do consistently * Turning focus on breathing pattern can in itself be a form of meditation practice * General rule of breathwork: if inhales are longer than exhales, you will shift into more alert state; if you focus on longer, more vigorous exhales you will relax * Three main considerations of meditation practice: (1) exteroceptive versus interoceptive focus; (2) breathing pattern; (3) continuum between interoception and dissociation * Practice to start meditation: + Close your eyes and try to put 100% of focus on the third eye or breathing for three breaths; + Open eyes and visually focus on one body part or area for three breaths; + Look at something in the environment for three breaths; + Focus on something further for three breaths; + Acknowledge you are a small body in a large world for three breaths; + Step back to interoception for three breaths + Remember, pay attention to breathing the whole time

Read the full notes @ podcastnotes.org

In this episode, I discuss the biological mechanisms of the state changes that occur during different types of mediation and describe how to develop the mediation practice optimal for you. I explain key meditation principles, such as using specific breathwork patterns and adjusting your perception to specific locations along the continuum between interoception, exteroception and dissociation. I discuss how meditation practices lead to long-term trait changes and neuroplasticity, including changing your default mood, reducing baseline anxiety/depression, increasing your ability to focus, enhancing relaxation, improving sleep, and increasing your overall happiness level. I also explain the concept behind the “third-eye center,” what mindfulness is from a biological standpoint, the power of ultra-brief meditations and how to select the best meditation and time and duration to meditate to meet your need. I also explain a novel open-eyed perception-based meditation that may enhance focus, relaxation and task-switching ability. Whether you are a novice or an experienced meditator or simply interested in how our brain controls different aspects of conscious awareness and self-regulation, this episode should interest you.

Thank you to our sponsors

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ROKA: https://www.roka.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

Huberman Lab Premium

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Meditation

(00:04:13) InsideTracker, Thesis, ROKA, Momentous Supplements

(00:08:25) Brief History of Meditation: Consciousness, Psychedelics, fMRI

(00:16:19) How the Brain Interprets the Body & Surrounding Environment; Mindfulness

(00:26:07) Neuroscience of Mediation; Perceptual Spotlights

(00:32:27) AG1 (Athletic Greens)

(00:33:41) Interoception vs. Exteroception

(00:42:20) Default Mode Network, Continuum of Interoception & Exteroception

(00:53:30) Tools: Interoceptive or Exteroceptive Bias, Meditation Challenge

(01:01:48) State & Trait Changes, Interoceptive & Exteroceptive Meditations, Refocusing

(01:07:35) Tool: Brief Meditations, Waking Up App

(01:10:30) “Third Eye Center” & Wandering Thoughts

(01:20:46) Mediation: Practice Types, Focal Points & Consistency

(01:24:10) Breathwork: Cyclic Hyperventilation, Box Breathing & Interoception

(01:30:41) Tool: Meditation Breathwork, Cyclic vs. Complex Breathwork

(01:39:22) Interoception vs. Dissociation, Trauma

(01:47:43) Model of Interoception & Dissociation Continuum

(01:53:39) Meditation & Dissociation: Mood, Bias & Corresponding Challenge

(02:00:18) Meditation & Sleep: Yoga Nidra, Non-Sleep Deep Rest (NSDR)

(02:11:33) Choosing a Meditative Practice; Hypnosis

(02:14:53) Tool: Space-Time Bridging (STB)

(02:25:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media

Title Card Photo Credit: Mike Blabac

Disclaimer

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Twenty Minute VC

Podcast Notes Key Takeaways * Check Out the 20VC Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Chris Sacca is the Founder and Chairman @ Lowercase Capital, one of the best performing funds in the history of venture capital with a portfolio including Uber, Stripe, Twitter, Instagram, Twilio, Docker and many more.

From interviewing some of the world's richest married couples, how did gaining wealth change their relationship and marriage?
What does Chris do to actively ensure his children remain hungry and know the value of money?

Chamath Palihapitiya is Founder & CEO @ Social Capital. Social’s portfolio includes the likes of Slack, Yammer, Front, Intercom and Carta to name a few.

What does Chamath mean when he says we need to think through the mindset of "infinite games" not finite games? How does this change how you think about money?
How does Chamath think about his relationship to risk today as a result?

Brad Gerstner is the Founder and CEO of Altimeter. Brad’s notable deals that he has helped lead include Snowflake, Mongo, Bytedance, Gusto, Unity, Okta, dbt, Modern Treasury, EPIC Games, Hotel Tonight and Zillow.

What is the most important thing parents can do to ensure that despite wealth, their children remain grounded and ambitious?
Why does Brad, despite being a billionaire, still live in a modest house and not spend on the excesses of life? How does Brad embrace essentialism with wealth?

Cyan Banister is one of the most successful and renowned early-stage investors in the last decade. Her portfolio includes the likes of SpaceX, Uber, Affirm, Opendoor Postmates, Niantic and Thumbtack to name a few.

Why did Cyan used to hate money? Why was she "anti-capitalist"?
How does Cyan approach risk management today? Why does she invest every dollar she makes back into the ecosystem?

George Zachary is a General Partner @ CRV, one of the nation's oldest and most successful early-stage venture capital firms with a portfolio including the likes of Airtable, DoorDash, Dropbox, Niantic and many more.

What did George learn about how the way people view you changes with your increasing wealth?
Why does George believe rich people like to hang out with rich people?

Biz Stone is best known as the Co-Founder of Twitter and Medium. Biz is also an investor in the likes of Slack, Square, Intercom, Beyond Meat and Blue Bottle Coffee.

What does Biz mean when he says, "wealth only serves to amplify the person you are?"

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My First Million

Podcast Notes Key Takeaways * Most people think that luck and risk are outside of their control, but that may not be entirely true * The four types of luck: blind luck, fortune favors the bold, chance favors the prepared mind and the luck that finds you * The four types of risk: mediocrity, safety, eyes-wide-shut, and market-execution-technical risk * Mediocrity is the biggest risk for someone that wants to be great * Instead of only thinking about putting your personal self at risk, think about whether or not you’re putting your dream at risk * Objectively evaluate if your current trajectory is leading you to where you ultimately want to be * People often think starting a company is risky, but the worst thing that can happen is it fails and you learn things along the way

Read the full notes @ podcastnotes.org

Episode #380: Shaan Puri (@shaanvp) talks about the different kinds of luck, how to put yourself in a position to be lucky, and how to mitigate different kinds of risk.

To submit your question and hear yourself on My First Million, go to MFMPod.com and click on the circle with the microphone in the lower right hand corner.

Links:

Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Artificial Intelligence Podcast

Podcast Notes Intro * If a giant corporation can de-platform the sitting president and “most powerful man in the world,” then he is not the most powerful man in the world, and the Apple, Google, Facebook, Twitter, and Amazon network leaders have become more powerful than the democratically elected leaders * The Future is Our Past Thesis: history is running in reverse, with similar scenarios but it will ultimately yield opposite outcomes * The United States was able to defeat Nazi Germany because it had a giant manufacturing base overseas; it simply out-produced the Nazis + Today, the United States’ manufacturing base is in China, the country it may fight a war with * Don’t be anti-conventional for the sake of being anti-conventional; iterate on conventional wisdom to contribute to progress * The coming decade in America will be green vs orange, not red vs blue; that is, the US dollar and its supporters vs Bitcoin and its supporters * Crypto Capital is an attractive alternative for countries that don’t want to be dominated by US media corporations (Woke Capital) or China (Communist Capital) * Digital property rights enabled by decentralized social media will spark a productivity boost that will mirror China’s switch from communism to capitalism * “The most predictable innovation in the world, in my view, is the AR glasses.” – Balaji Srinivasan * Balaji predicts that the future will consist of much smaller digital networks, but each will be much “deeper” in regards to its tech stack, thus creating a Network State * Instead of dismissing the FDA, Federal Reserve, and Academic Establishment, optimistically think of the v1, v2, v3 of them and build them * The ideal combination of skills that young people should aspire to acquire are those of a full-stack engineer and full-stack influencer * If you’re going to build a billion-dollar company, you should also build a media company in tandem with it that has a million followers because the legacy media companies will not be economically or socially aligned with your business * New states and countries can advance on their own axis; they don’t have to be “with or against” America, as much as politicians want you to believe that

Read the full notes @ podcastnotes.org

Balaji Srinivasan is an angel investor, tech founder, philosopher, and author of The Network State: How to Start a New Country. He was formerly the CTO of Coinbase and General Partner at Andreessen Horowitz. Please support this podcast by checking out our sponsors: – Policygenius: https://www.policygenius.com/ – Blinkist: https://blinkist.com/lex to get 25% off premium – Notion: https://notion.com – Onnit: https://lexfridman.com/onnit to get up to 10% off EPISODE LINKS: Balaji’s Twitter: https://twitter.com/balajis Balaji’s Website: https://balajis.com Books: 1. The Network State: https://thenetworkstate.com 2. Reputation and Power: https://amzn.to/3eyQiF6 3. Exit, Voice, and Loyalty: https://amzn.to/3TpuLNP 4. Seeing Like a State: https://amzn.to/3MJfvcD Articles: 1. Bitcoin

Exit, voice, and loyalty;: Responses to decline in firms, organizations, and states

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Nudge - Marketing Science Simplified✓Claim

Podcast Notes Key Takeaways * Jose Mourinho is known for his psychological approach to games, using mind games in press conferences and interviews to undermine his opposition and motivate his team * A mind game is psychologically manipulative behavior intended to discomfort another person or gain an advantage over them * He uses three mind game tactics to improve his team’s chances of success: signaling, reactants, and reframing * Signaling: conveying information, belief, and trust by means of a gesture, an action, or a sound * Reactants: the motivation to regain something after it has been lost, threatened, or taken away from you * Reframing: explaining a situation in a different way to help his players look at a problem from another angle * Using signaling and reactants to influence, persuade, and motivate can work, but not if they’re used endlessly; eventually, they will start to lose their potency or backfire on you * Be sure to match signaling with humility; as the leader, it is vital to take responsibility for bad results * When people are told they cannot do something, the forbidden activity becomes more attractive and alluring to people, i.e. if you tell someone they can’t do something, they are far more motivated to do it * Approaches that work for Jose might not work for you; he is a one-of-a-kind operating in a unique setting

Read the full notes @ podcastnotes.org

Jose Mourinho is one of the world's most successful football managers. He has consistently turned good teams into the world’s best. He’s done so by signing fantastic players, by mastering tactics, but also by using psychological mind games to motivate his players and undermine his opposition.

In this episode, I share interviews with Mourinho to pick apart why he used mind games, what he aimed to achieve, and whether or not they really worked.

Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list

Follow me on Twitter: https://twitter.com/p_agnew

Connect with me on LinkedIn: https://bit.ly/3mcmaiZ

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CryptoThe Investor's Podcast (TIP)

Podcast Notes Key Takeaways * The creation of new and better technology is the result of trying to solve our problems in a better way * Your brain by itself is a small computer with a limited amount of computing power; linking more and more brains together forms a supercomputer with much more computing power than any single computer, and creates society as we know it + However, linking together requires trust, and a breakdown in that trust corrupts the output of the supercomputer * When a new idea emerges in the free market, the incumbent companies tend to try and defend their monopoly over the old idea instead of trying to adopt the new idea * “Abundance in money creates scarcity in everything else. Scarcity in money creates abundance in everything else.” – Jeff Booth * Money is just information; you don’t actually want more money, you want more of what you believe money buys you * A system using an inflationary monetary policy is based on the lie that inflation is required for a productive society * If 1) money is just information, and 2) money is being manipulated by central banks at an unprecedented rate to avoid a credit collapse of the system, then 3) misinformation must be growing through the system * The productivity gains from technologies competing on the free market should result in humans getting more value, but the value cannot transfer to society in a system that has an inflationary monetary policy * If it’s hard to grasp the changes that the iPhone would elicit, imagine how difficult it is to grasp the changes that a software protocol like Bitcoin will elicit * It’s useless to try and measure the new system with an error code from the old system * DARPA created the internet’s base-layer protocol (TCP/IP) in the 1960s, but it wasn’t until HTTP was created on layer four that connected the stack that created the internet as we know it today * Bitcoin is a base-layer protocol for money the same way TCP/IP is the base-layer protocol for the internet

Read the full notes @ podcastnotes.org

IN THIS EPISODE, YOU’LL LEARN:

01:20 - Jeff's first principles overview of energy, money, and resource optimization.
12:42 - Why is the adoption of Bitcoin bottom up and not top down?
15:41 - A system of growing misinformation and why.
25:47 - Why are open protocols so difficult to understand?
32:29 - What is the blockchain Trilemma?
40:12 - Why is decentralization combined with security for the first time such a big deal?
50:46 - Jeff's opinion on why energy must be inserted into money.
01:11:28 - What are the important Bitcoin fundamentals to be focusing on right now?
01:16:33 - If Jeff had to recommend something to the G20, what would it be?

Disclaimer: Slight discrepancies in the timestamps may occur due to podcast platform differences.

BOOKS AND RESOURCES

Jeff's Twitter.
Ego Death Capital.
Related Episode: Bitcoin Deep Dive on Energy Misconceptions w/ Michael Saylor - BTC099.
Related Episode: A Hyper-Bitcoinized World w/ Jeff Booth - BTC052.
The article from Baseload BTC: Green-Shaming No More.

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Aarthi and Sriram's Good Time Show ✓

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Podcast Notes Key Takeaways * Virtual Reality (VR) is the final platform because the only step after VR is mind-melding into the Borg; fully-formed VR makes technologies like phones, televisions, and desktop PCs obsolete * Palmer Luckey started a national security company because he thought it was the most important problem that he could work on, and one that his peers were not working on * Big Tech companies were refusing to work with the military because they were beholden to the US’s strategic adversaries * There is a vocal minority in tech who are anti-military, and the tech executives at these companies use this vocal minority as a smoke-screen reason to not do meaningful work with the US military when in reality the executives are just trying to appease China * Most defense companies operate on a cost-plus basis: they are paid for time and materials, and then a fixed percentage of profit on top * Cost-plus contracts warp incentives; defense contractors can make more money by taking longer, designing a more expensive system, and running over on costs because the percentage they make on top is just a percentage of those costs * Anduril uses its own money to build the products it sells to the US military and its allies * Many countries “Stand with Ukraine” and “Reject Russian Violence” while simultaneously giving Russia billions of dollars to fund its war machine in exchange for oil and natural gas + They stand with Ukraine up until the point it inconveniences them * The best time to wave the magic wand to resolve the Russia-Ukraine conflict was years or decades ago * Palmer Luckey believes China is more likely to launch a blockade around Taiwan than a full-scale invasion * The worst-case scenario for the United States is the CCP gains control over Taiwan’s semiconductor industry and only allows semiconductors to be sent to China * Palmer Luckey believes that the next-generation category of power projection technologies (AI, hypersonics, etc.) will make the traditional category (aircraft carriers, Top Gun stuff) obsolete * There is a cultural fetishization of being “the founder”, that is healthy in some ways, but it downplays the importance of other roles at startups like the chief technical officer, lead hardware engineer, etc. * Do not start a technology company if you really love technology and programming

Read the full notes @ podcastnotes.org

In this episode, Aarthi and Sriram talked to Palmer Luckey, the founder of Oculus and now the founder and CEO of Anduril. We talked about Palmer's unique childhood, how he started Oculus and essentially made re-ignited the VR movement, sold to Meta, got fired, and then went on to start another challenging company called Anduril which focuses on building defense technology. We talked about Palmer's recent trip to Ukraine, the current state of the Ukraine/Russia, China/Taiwan and the threat of nuclear war. We also talked about John Carmack, Elon Musk, dealing with haters, working on hard problems and what drives incredibly productive people and his advice for founders.

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Huberman Lab

Podcast Notes Key Takeaways * The human brain is shaped differently depending on sounds you are exposed to in utero and throughout the first years of brain development * It’s probably best to skip the white noise machine to help your babies sleep – our brain is structured to hear environmental noises; constant white noise exposure may lead to delays * Whether you are right-handed or left-handed is strongly genetically determined * The earlier, more intense, and longer you can have exposure to a second language – the better; human interaction allows for greater specialization of the language * Memory is widely distributed across the brain which is good because even in the event of head injury or illness requiring surgery, memory is generally preserved * New technologies are being studied to give paralyzed and nonverbal patients a chance to communicate again through the use of electrodes connected from the brain to a computer which uses AI to translate

Read the full notes @ podcastnotes.org

My guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication.

Thank you to our sponsors

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Huberman Lab Premium

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Eddie Chang, Speech & Language

(00:03:00) Levels, Eight Sleep, InsideTracker, Momentous Supplements

(00:07:19) Neuroplasticity, Learning of Speech & Environmental Sounds

(00:13:10) White Noise Machines, Infant Sleep & Sensitization

(00:17:26) Mapping Speech & Language in the Brain

(00:24:26) Emotion; Anxiety & Epilepsy

(00:30:19) Epilepsy, Medications & Neurosurgery

(00:33:01) Ketogenic Diet & Epilepsy

(00:34:56) AG1 (Athletic Greens)

(00:36:10) Absence Seizures, Nocturnal Seizures & Other Seizure Types

(00:41:08) Brain Areas for Speech & Language, Broca’s & Wernicke’s Areas, New Findings

(00:53:23) Lateralization of Speech/Language & Handedness, Strokes

(00:59:05) Bilingualism, Shared Language Circuits

(01:01:18) Speech vs. Language, Signal Transduction from Ear to Brain

(01:12:38) Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations

(01:17:37) Mapping Language in the Brain

(01:20:26) Plosives & Consonant Clusters; Learning Multiple Languages

(01:25:07) Motor Patterns of Speech & Language

(01:28:33) Reading & Writing; Dyslexia & Treatments

(01:34:47) Evolution of Language

(01:37:54) Stroke & Foreign Accent Syndrome

(01:40:31) Auditory Memory, Long-Term Motor Memory

(01:45:26) Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI)

(02:02:14) Neuralink, BCI, Superhuman Skills & Augmentation

(02:10:21) Non-Verbal Communication, Facial Expressions, BCI & Avatars

(02:17:35) Stutter, Anxiety & Treatment

(02:22:55) Tools: Practices for Maintaining Calm Under Extreme Demands

(02:31:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media

Title Card Photo Credit: Mike Blabac

Disclaimer

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Infinite Loops

Podcast Notes Key Takeaways * The majority of companies who have made money on the internet have done so via closed AI; Stability AI is an open source alternative to Big Tech’s closed AI system * Open systems are more robust, resilient, and safe than closed systems which often become brittle, fragile, and centralized * People are not the same around the world; the moral and ethical conversation around AI improves when more people from all around the world can participate * The last generation of AI was patterns-based; the next generation of AI will be principles-based * Combining principles-based AI with patterns-based AI will solve problems that were previously unsolvable * The AI of the future will be too powerful to be controlled by any one company or government; that would be too much power for an unelected company, and governments should not control it either * Giving everyone personalized access to intelligent resources will enable everyone to out-compete the legacy systems and create a better world * Open AI helps shift society’s mindset from scarcity to abundance * It’s important for AI to be open so that countermeasures can be built to prevent corporations and governments from creating the panopticon * A closed, AI-enhanced government would make it impossible for the individual to rise up and change its government * AI is the greatest lever that humanity has ever been given, according to Jim O’Shaughnessy * Artificial intelligence is one of the most powerful technologies that we’ve created because this technology is us and extends us * The bad guys have this tech right now; in order to limit the damage they can do, AI must be made open to benefit most from cognitive diversity

Read the full notes @ podcastnotes.org

Emad Mostaque is the founder and CEO of Stability AI, the company behind Stable Diffusion.

Emad joins Stability AI’s recently announced Executive Chair of the board of directors Jim O’Shaughnessy to discuss the future of AI, the benefits of open source software, and much more.

Important Links:

Stability AI
Stable Diffusion Launch Announcement
Stability AI’s Twitter
Emad’s Twitter
Jim’s announcement as Executive Chair

Show Notes:

The open vs closed AI debate
How will open AI lead to better outcomes for AI safety?
How will AI allow us to to solve previously unsolvable problems?
How AI can transform education
AI and storytelling
What is ‘clean’ data?
Can AI technology increase IQs across the entire world?
The future: optimism, pessimism, jobs, AI alignment and the panopticon
Why closed AI is a bad business model
Anticipating and defending against future problems
What two ideas would you like to give everyone in the world?

Books Mentioned:

The WEIRDest People in the World; by Joseph Henrich

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HVMN Podcast

Podcast Notes Key Takeaways * Explosion of ketones as a field of study: (1) ketones are a potent but accessible intervention (legal, accessed through diet or exogenous; (2) scientists are living the lifestyle of what they’re studying which helps credibility, influence, experience * “Ketones can rapidly change brain energy metabolism and the neuropharmacology of your brain in a way that’s neuroprotective and anti-seizure.” – Dr. Dom D’ Agostino * There should be a duty to disseminate translatable, clear research to the public if funded through government means * Ketones improve brain energy signaling metabolism, resilience, and enhance ability to maintain cognitive and physical performance in extreme environments – both environmental and physiologic * Even within the ketogenic diet, there are many routes to go and options for exogenous ketones as supplement – like any diet, it needs to be personalized to your needs (a continuous glucose monitor can help) * Starting in early middle age, natural uptake of glucose declines but ketone uptake is retained in the aging brain – ketones can circumvent glucose transporter and provide the energy for proper function * The greatest effect of ketogenic diet on athletic performance will likely be over time where you’ll see improvements in recovery, epigenetic effects, anti-inflammatory effects * Tip: consuming carbohydrates with exogenous ketones (such as a ketone salt, MCT) will minimize glycemic variability * “Completely excluding carbohydrates, fruit, and vegetables to the extent we do that with a clinical ketogenic diet is not optimal [for everyday]. A more diverse diet with plants, vegetables, different protein sources, with exogenous ketones would be more optimal.” – Dr. Dom D’Agostino + Instead, try a Mediterranean diet with exogenous ketones for supplementation with about 50-100g carbohydrates

Read the full notes @ podcastnotes.org

Dr. Dominic D’Agostino is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC). Dr. Angela Poff is a Research Associate in the Department of Molecular Pharmacology and Physiology at the University of South Florida in Tampa, FL, and Co-Founder of Metabolic Health Initiative. Dr. Latt Mansor and Geoff Woo met Dr. D’Agostino and Dr. Poff in person to talk about the state of the art of ketone research in 2022. Key point topics and studies mentioned: * Role of ketones and the future direction of ketone research in: + Athletic performance/ extreme environment + Mitochondrial protection in astronauts in space + Cancers + Metabolic psychiatry + Alzheimer’s and dementia

Optimal blood ketone levels for health benefits
Keto vs. carnivore vs. plant-based diets

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Huberman Lab

Podcast Notes Key Takeaways * Seated exercise tip: perform soleus pushups/seated calf raise (start with feet planted and press onto toes, raising heels) for surprisingly dramatic improvements in blood sugar and metabolic boost * Huberman’s fitness protocol: Sunday – Endurance; Monday – Legs; Tuesday – Heat/cold cycling; Wednesday – Torso push/pull; Thursday – High effort, short cardio; Friday – High-intensity interval training + Tweak the routine and shift to personalize but keep the broad goals – the specific days of each workout aren’t critical but specific spacing is * Huberman’s hypertrophy protocol: 3-4 weeks in 5-8 reps at heavyweight x 3-4 sets per exercise with 2-4 minutes rest; then next month, switch to 8-15 reps at lighter weight x 2-3 sets per exercise with 90 sec rest * Resistance training best practice: choose 2 exercises per muscle group – one where the muscle is at maximal contraction at the end of the movement (e.g., bent row) and another where there’s a stretch or full range of motion at the beginning of the movement (e.g., pull up) * To lower heart rate between sets, practice physiologic sighs: 2 full inhales through nose + 1 full exhale of all air through the mouth * Mind-muscle connection: certain muscles will grow bigger and get stronger depending on your ability to contract that muscle in the absence of load * Do 3-5 minutes of deliberately slow breathing after each training session to downshift the nervous system and relax your mind and body

Read the full notes @ podcastnotes.org

I describe a fitness protocol that maximizes all the major sought-after aspects of physical fitness, including strength, endurance and flexibility. I discuss fundamentals of resistance training protocols, including repetitions, sets, inter-set and inter-workout rest periods and periodization of intensity and volume to improve strength and hypertrophy. I also explain how to integrate this with endurance training across the week by controlling the duration, timing and intensity of cardiovascular workouts. I also cover science-based protocols on leveraging the mind-body connection, deliberate breathing (during and after exercise), stretching, deliberate heat and cold exposure, and non-sleep deep rest (NSDR) for better workout performance and faster recovery. Further, I tackle a range of real-world issues that can affect a consistent training schedule, such as whether you should train if you are sick, have had a poor night of sleep or had a stressful event and how to start training again after a break and whether you should train in a fasted or fed state. Physical fitness is a key variable for immediate and long-term health. This episode provides a modifiable “foundational” template that can be adjusted based on your current fitness level, goals, time constraints, and access to different types of equipment.

Thank you to our sponsors

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Foundational Protocol for Fitness

(00:03:35) Huberman Lab Premium

(00:04:35) Tool: Soleus (Calf) Push-Ups, Glucose Utilization & Metabolism

(00:14:42) InsideTracker, ROKA, Helix Sleep, Momentous Supplements

(00:18:53) Core Principles of Fitness & Modifiable Variables

(00:23:37) Day 1: Long Endurance Workout

(00:34:38) Day 2: Leg Resistance Training, Strength & Hypertrophy

(00:38:09) Athletic Greens (AG1)

(00:39:22) Key Principles of Resistance Training

(00:51:10) Day 3: Heat & Cold Exposure, Recovery

(01:00:35) Day 4: Torso & Neck Resistance Training

(01:09:55) Day 5: Moderate Intensity Cardiovascular Training, Running Alternatives

(01:16:43) Day 6: High-Intensity Interval Training, Maximum Heart Rate

(01:24:10) Day 7: Arms, Neck & Calves Resistance Training

(01:28:45) Flexibility of Foundational Protocol, Workout Spacing

(01:33:00) Tool: Mind-Muscle Contraction, Physiological Sighs

(01:37:10) Safety & Endurance/Cardiovascular Workouts

(01:38:32) Tool: Stress or Poor Sleep & Workouts, Recovery & NSDR

(01:41:20) Should You Train Fasted or Fed?

(01:43:58) Tool: Static Stretching & Flexibility, Irradiation & Resistance Training

(01:49:10) Tool: Hanging from a Bar & Fitness Metric

(01:50:16) Should You Train Sick?, Ramping Training

(01:53:33) Tool: Deliberate Slow Breathing & Recovery

(01:55:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media

Title Card Photo Credit: Mike Blabac

Disclaimer

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CryptoThe Investor's Podcast (TIP)

Podcast Notes Key Takeaways * Pack animals use a proof-of-power protocol to establish a state of legitimate ownership consensus and chain of custody of their property * As Sapiens evolved, we came up with imaginary alternatives to the physical proof-of-power protocol by appointing people with imaginary power through the creation of abstract power hierarchies * Agrarian society abandoned physical power hierarchies and adopted abstract power hierarchies which granted people of rank resource control authority + Physical power projection to settle disputes over property was morally condemned because it was energy-intensive and often resulted in injury * Throughout history, god-kings have taken advantage of their trust-based, abstract power hierarchies and exploited their domesticated populations to egregious scales * The benefits of using abstract power (efficiency and no physical injuries) tend to break down over time because the rulers must be trusted not to exploit the people they rule * It is easier to exploit people through positions of higher rank (abstract power) than exploiting them through methods of physical power + God kings with abstract power can expand their claim on resource control authority at zero cost, while the pack animal in a proof-of-power hierarchy must exert large amounts of energy and risk high costs to expand its control authority * Abstract power hierarchies are very attractive to parasites, sociopaths, and individuals that want a lot of control and authority over resources because all they need is “rank” * If a god-king has abstract power over machines, and people become increasingly more dependent on those machines, then the god-king’s power extends to power over people too * “People today in cyberspace have levels of abstract power that would make the pharaohs blush.” – Jason Lowery * Proof-of-stake is effectively proof-of-rank: choosing proof-of-stake over proof-of-work forfeits your capacity to project physical power to defend yourself in cyberspace * Proof-of-work secures your access to your property by preserving your ability to impose severe physically-prohibitive costs on anyone that would try to take it from you, deny your access to it, or exploit your rules * Bitcoin is a philosophy about determining the basis for establishing resource control authority and reaching a consensus on the legitimate state of ownership and chain of custody of an underlying piece of property * In a proof-of-stake system, a single entity that controls 60% of all stake can split that stake among millions of validators and then use those validators to tactfully withhold specific transactions from the blockchain + Tactfully withholding transactions = resource control authority * People are different and have different ideological beliefs; it’s unlikely that everyone operating on a proof-of-stake network will agree that the censored chain is bad * Currently, Jamie Dimon is the apex predator in his abstract power hierarchy; as the god-king, he will do whatever he can to maintain his abstract power * Abstract-power-god-kings such as Vitalik Buterin and Jamie Dimon try to get people to pay attention to everything but Bitcoin, a protocol that uses physical cost functions and decentralizes the physical control authority over resources + They cannot have resource control authority over Bitcoin, so they lure you into the abstract power hierarchy that they control * Most crypto projects copy Bitcoin’s software, remove the proof-of-work component of it, and replace it with an “innovation” that does one thing and also grants them resource control over the ledger * Vitalik Buterin does not understand that the physical components of the system is what contributes most to security * We don’t ask meteorologists about the technical merits of cloud computing; just because proof-of-work’s primary use case has the word “coin” in it does not make the United States Treasury Department or the Federal Reserve qualified to talk about the technical merits of proof-of-work * If Bitcoin is a power projection technology and a new way for people to defend themselves, or particularly their property, then the United States must take it extremely serious from a national strategic standpoint * “My recommendation to any policy maker that might be listening to this: the last people you should be listening to are bankers and financiers about power projection technology.” – Jason Lowery * Just like humans use watts to project physical power in the domains of land, air, sea, and space, humans will use watts to project physical power in cyberspace via proof-of-work to make the cost of attacking them as high as possible

Read the full notes @ podcastnotes.org

IN THIS EPISODE, YOU’LL LEARN:

01:58 - Why are property rights an important starting point for understanding the differences between Proof of Work (PoW) and Proof of Stake (PoS)?
07:41 - What is Abstract Power versus Physical Power and why are they important for understanding PoS Vs PoW?
20:45 - Why do the rules around property rights keep breaking down throughout time?
40:45 - Explain the importance of basic computer science and how computer programs work so we can understand the differences in PoS and PoW.
49:50 - A general introduction to PoS and PoW.
57:25 - Hal Finney and Adam Back’s contributions to developing the first blockchain.
01:15:15 - If you were going to exploit a PoS or PoW system, how would that work?
01:23:08 - Creative destruction and how it applies to protocols.
01:31:59 - Jason’s thoughts on Jamie Dimon liking everything but PoW.
01:38:15 - Vitalik Buterin’s comments on PoS not being tethered to physical reality.
01:42:17 - How has the faculty at MIT responds to your research?
01:58:30 - If you had a message to policy makers, what would it be?

*Disclaimer: Slight timestamp discrepancies may occur due to podcast platform differences.

BOOKS AND RESOURCES

Jason Lowery'sTwitter
Jason Lowery’s website and writings on Bitcoin.

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LABOSSIERE PODCAST ✓

Claimed

Podcast Notes Key Takeaways * The long-term legacy of your contribution to society is bounded to the fate of the society you are in * Figuring out why societies fail will help humans take measures to mitigate such failures and allow human contributions to compound over generations * Even though everyone wants their society to succeed, their individual incentives might encourage them to work against other members of the same society * Human history is a stuttering arc of progress where civilizations rise, achieve some sort of peak, and ultimately fail, and then another civilization picks up the remnants and start again * Providing a useful information inheritance is the best thing we can do for future generations * An immortal society is a boundless society where almost all human effort can compound and accumulate over time * Societies that celebrate their most successful outliers will generate people who are capable of solving their hardest problems * The collapse of civilization includes a massive decline in population, material wealth, and human knowledge * Societies that undergo stagnation and forgo growth have a compounding risk of collapse over time * The Great Founder Theory: a small, exceptional group of people are ultimately responsible for the creation of new institutions that drive growth and innovation across a society * A great founder must operate within a social reality so he is not disconnected from society, but also be differentiated enough so that is not just like everyone else * On live versus dead players: A live player is a person or well-coordinated group of people that is able to do things they have not done before, whereas a dead player operates off of a script and is incapable of doing new things * The ability to successfully jump career tracks is evidence of being a live player + Examples include Arnold Schwarzenegger and Elon Musk * People are not paying enough attention to our aging population; an old population is less capable of dealing with the changes demanded by technology

Read the full notes @ podcastnotes.org

Samo Burja is the founder of Bismarck Analysis, a consulting firm that investigates the political and institutional landscape of society. He’s also a Research Fellow at the Long Now Foundation where he studies how institutions can endure for centuries and millennia.

Samo is also Senior Research Fellow in Political Science at the Foresight Institute, where he advises how institutions can shape the future of technology.

He writes and speaks on history, institutions, and strategy with a focus on exceptional leaders that create new social and political forms. He’s systematized this approach as “Great Founder Theory.”

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The Daily Stoic

Podcast Notes Key Takeaways * Too much pleasure taken too far becomes its own kind of pain and punishment * Premeditatio Malorum – visualization of negative outcomes + Mentally prepare for something to go wrong; that’s how you have a plan and be able to shrug it off/ move forward and not be devastated * Search yourself for vices, but look for virtues in other people + Self-control and self-discipline are not something you project on other people * Those who long for posthumous fame forget that they won’t be around to enjoy it * “Often the most powerful, the most ambitious, the people you look up to are actually a lot less free-er, not just that you think, but that you would ever want to be.” – Ryan Holiday * Time is our most precious resource. If we know how to manage our time, life is plenty long * What happens in Vegas, stays in Vegas; you are still stained by the shame + When you do something bad in the pursuit of pleasure, the pleasure disappears quickly but the shame endures * Life starts with the little choices; the decision to get up early, the decision to go work out, the decision to get down and do your work instead of procrastinating

Read the full notes @ podcastnotes.org

📕 Ryan Holiday's new book "Discipline Is Destiny" is out now! We’ve extended the pre-order bonuses for the next week—among them is a signed and numbered page from the original manuscript of the book. You can learn more about those and how to receive them over at Dailystoic.com/preorder.

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James Altucher Show

After the unexpected and untimely passing of Coolio, we have decided to re-air this early episode of the podcast.

From the original release notes:

"Grammy Award-winning and multi-platinum artist Coolio joins The James Altucher Show to share his story of success. With more than 30 million records sold globally, Coolio gives a side to his story that most people don’t know.

Teacher? Psychologist? Author? There are many surprising career paths that Coolio he had interests in pursuing.

You’ll hear how his love of music and his ability to understand and connect with people enabled him to create hip-hop poetry unlike anyone else.

Something that most people don’t realize is that one of Coolio’s biggest hits, “Gangsta’s Paradise,” caused him some career conflicts, and here you get all the details.

What is truly inspiring is his passion for life and his ability to choose himself. From a rough childhood and being bullied to creating his career from scratch, you get the exclusive details from Coolio himself.

He is living proof that believing in yourself is a skill, one that everyone can master if they put their mind to it."

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I write about all my podcasts! Check out the full post and learn what I learned at jamesaltucher.com/podcast.

Thank you so much for listening! If you like this episode, please rate, review, and subscribe to “The James Altucher Show” wherever you get your podcasts:

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Huberman Lab

Podcast Notes Key Takeaways * Evolution of psychiatry: phase I – must be something genetic or how you were raised; phase II – must be a chemical imbalance or something chemically missing * There’s actually a decrease in the level of activity in the brain on psychedelics, but the connectivity in regions increases * We’re all taught to retain some level of control in our day-to-day lives – part of the therapeutic effect of psychedelics is about untethering, letting go, and letting the system assume a natural state you’ve been fighting * Mental health disorders exist on a range; you may not reach a clinical level of OCD but you may have some tendencies or habits * “If you can rid yourself of all to social and cultural constructions and re-examine these if we just discovered these today, we’d say that [psychedelics] are a huge breakthrough in psychiatry.” – Dr. Nolan Williams * Psychedelics allow you to enter into a highly plastic state and reconsolidate memory which may drive a therapeutic effect * Anti-psychotic therapeutic effects of cannabis are from the CBD and not the THC – the problem is we have potent strains now heavy with THC and low in CBD * Transcranial magnetic stimulation (TMS) has the potential to send a signal to the prefrontal cortex and use the brain’s own communication style to get it out of a depressive state – you’re tapping into core circuitry with minimal side effects (unlike tinkering neurotransmitters)

Read the full notes @ podcastnotes.org

In this episode, my guest is Nolan Williams, M.D., a triple board-certified psychiatrist, neurologist and professor of psychiatry and behavioral sciences at Stanford School of Medicine. He is also the Director of the Stanford Brain Stimulation Lab. We discuss clinical applications for brain stimulation, behavioral protocols and novel drug treatments to halt and reverse mental health disorders, including depression and post-traumatic stress disorder (PTSD). We first discuss the neural circuits for self-identity and mood and stress control. We discuss Dr. Williams’ work using transcranial magnetic stimulation (TMS) to depression, trauma, PTSD, and other mood disorders. We then dive deep into the history, biology, modern use, and safety margins of the various psychedelics, including MDMA, LSD, ketamine, ibogaine, ayahuasca, and psilocybin, as well as cannabis and the use of SSRIs in both adults and children. Finally, we discuss behavioral treatments for mental health disorders, including sleep and sleep deprivation, light exposure, exercise, and training to control the brain-heart-rate pathways. Regardless of age, all those interested in mental health should benefit from the incredible breadth and depth of Dr. Williams’ knowledge and the clarity with which he conveys that information.

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Nolan Williams, Brain Stimulation & Depression Treatment

(00:03:31) Huberman Lab Premium

(00:04:42) InsideTracker, Eight Sleep, ROKA

(00:08:37) Momentous Supplements

(00:09:16) Depression, Risk Factors, Emergency Psychiatric Treatments

(00:15:11) The Brain-Heart Connection, Vagus Nerve, Prefrontal Cortex

(00:17:51) Right vs. Left Brain Hemispheres & Mood Balance, Connectome

(00:22:34) Heart Rate & Depression, Behavioral Interventions, Transcranial Magnetic Stimulation (TMS)

(00:33:02) Prefrontal Cortex & Cognitive Control, TMS

(00:37:46) AG1 (Athletic Greens)

(00:39:00) Belief/Identity “Rules”, Re-scripting, TMS & Talk Therapy

(00:45:49) Dorsolateral Prefrontal Cortex, TMS & Depression Treatment

(00:48:36) Cingulate Cortex & Emotion, Dissociation & Catatonia

(00:54:27) Ketamine, the Opioid System & Depression; Psychedelic Experience or Biology?

(01:03:42) SSRIs, Serotonin & Depression; Childhood, Chemical Imbalance or Circuit?

(01:13:58) Memories & “Rule” Creation; Psilocybin & “Rule” Resolution

(01:21:00) MDMA & Post-Traumatic Stress Disorder (PTSD) Treatment, Psilocybin & Depression Treatment

(01:24:12) Is MDMA Neurotoxic?, Drug Purity, Dopamine Surges, Post-MDMA Prolactin

(01:30:38) Psilocybin, Brain Connectivity & Depression Treatment

(01:34:53) Exposure Response Prevention: “Letting Go” & Depression Treatment

(01:41:23) Normal Spectrums for Mental Health Disorders

(01:45:35) Ibogaine & “Life Review”; PTSD, Depression & Clinical Trials

(01:57:16) Clinical Use of Psychedelics

(02:01:59) Ayahuasca, Brazilian Prisoner Study

(02:06:55) Cannabis: THC, CBD & Psychosis, Clinical Uses

(02:14:52) Personal Relative Drug Risk & Alcohol

(02:20:42) Circadian Reset for Depression, Sleep Deprivation, Light

(02:28:43) Stanford Neuromodulation Therapy (SNT) Study

(02:34:25) Space Learning Theory & TMS Stimulation

(02:45:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Neural Network Newsletter, Social Media

Title Card Photo Credit: Mike Blabac

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * Check out The Drive Episode Page & Show Notes

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Celia Morgan is a Professor of Psychopharmacology at the University of Exeter who has authored numerous publications on the potential therapeutic uses of ketamine in mental healthcare. In this episode, Celia dives deep into the neurobiology of ketamine, how it affects users, and how it differs from other, more classical psychedelics (LSD, MDMA, PCP, and psilocybin). She explains the potential promise of ketamine as a treatment for recalcitrant depression and addiction, and she details the results from her clinical trials in these areas. She discusses the importance of using ketamine in combination with psychotherapy to maximize its benefits, the potential risks associated with ketamine use, and advice for those interested in the therapeutic use of ketamine.

We discuss:

Celia’s training and interest in ketamine [2:15];
The history of ketamine, medical uses, and use as a party drug [3:30];
Neurobiology and pharmacology of ketamine [8:15];
Ketamine regulation and abuse, and how it compares with psychedelics and other molecules [18:15];
Ketamine as a therapeutic for depression [30:45];
The brain under the influence of ketamine and theoretical mechanisms for its anti-depressive effects [48:00];
Risks and concerns with overusing ketamine, and what an intermittent or maintenance dose might look for a patient [57:15];
Treating addiction with ketamine: Celia’s studies of alcohol dependance [1:04:00];
Advice for people considering the therapeutic use of ketamine [1:19:45];
More.

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Huberman Lab

Podcast Notes Key Takeaways * Nicotinic receptors and cannabinoid receptors are not in the brain for smoking tobacco or marijuana; they are endogenous receptors that support specific functions (such as acetylcholine) when appropriate * Cannabis dependence: when smoked or ingested, THC and CBD bind to cannabinoid receptors and tap into endogenous receptors with much more potency – your endogenous receptors are outcompeted * Sativa strains increase mood, alertness, and focus of the prefrontal cortex while decreasing stress and threat detection in the amygdala – this combination allows people to enter narrowed focus * Indica strains reduce the activity of the prefrontal cortex and induce relaxation and sedative effects but also lead to profound defects in short-term memory because it reduces the activity of the hippocampus * There are no predictors of what your reaction will be to a given strain (e.g., whether you experience relaxation or paranoia) * “Cannabis increases creativity but through changes in personality that tap into the creative process, rather than directly impacting the neural circuits that, for instance, ‘turn on’ creativity.” – Dr. Andrew Huberman * Smoking cannabis increases prolactin levels (especially in those who smoke more than twice per week); dopamine and prolactin are mutually inhibitory – this is important in sexual arousal which will be suppressed if prolactin is elevated with cannabis use * Fertility: THC (not CBD) is inhibitory for gonadotropin-releasing hormone which ultimately reduces testosterone in men, ovarian health in women * “Cannabis use itself makes people 4x likelier to develop a chronic, major depression.” – Dr. Andrew Huberman * Chronic cannabis is not safe for the developing brain and body because of thinning of gray matter that occurs – risks include depression, anxiety, psychotic events, inability to balance mood * The more potent the THC concentration, the higher the likelihood of developing a major anxiety disorder or psychotic episode later in life

Read the full notes @ podcastnotes.org

In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Cannabis (Marijuana)

(00:04:46) New: Huberman Lab Premium

(00:07:03) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety

(00:10:08) Levels, Thesis, InsideTracker

(00:14:01) Momentous Supplements

(00:15:08) Cannabis Strains, Psychoactive Compounds: THC & CBD

(00:19:34) Sativa vs. Indica, Stimulant vs. Relaxation Effects

(00:25:55) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains

(00:30:41) AG1 (Athletic Greens)

(00:31:56) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)

(00:40:35) THC, CBD vs. Endogenous Cannabinoids, Dependence

(00:43:14) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function

(00:53:07) Biological Effects of Cannabis

(00:56:29) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia

(01:04:58) Cannabis Indica & Subjective Effects, Memory, Dosage

(01:09:41) Brain Areas Affected by THC & CBD, Side Effects

(01:16:08) Creativity: Convergent vs. Divergent Thinking & Dopamine

(01:26:41) Does Cannabis Increase Creativity?

(01:35:08) Chronic Cannabis Use & Changes in Speech Patterns

(01:46:46) Cannabis & Libido, Dopamine & Prolactin

(01:56:55) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility

(02:06:53) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences

(02:10:06) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development

(02:18:13) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance

(02:25:57) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis

(02:34:36) Adolescent Cannabis Use: Brain Development & Mental Health Disorders

(02:41:44) Cannabis & Pain Management, Divergent Effects of Cannabis

(02:44:54) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn

Title Card Photo Credit: Mike Blabac

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All-In with Chamath, Jason, Sacks & Friedberg

Podcast Notes Key Takeaways * It’s an end of an era for Big Tech: they’re transitioning from a phase of unfettered growth into their next phase where they must learn to operate like a cash-cow business * When the growth engines of Apple and Google slow, other tech companies don’t have to offer competitive compensation, extra benefits, and extravagant workplace environments to compete for talent as they once did * “Nobody is talking about a soft landing anymore. In fact, I think we’re all wondering who is flying the plane.” – David Sacks on the Federal Reserve * Financial markets have always had a “Fed Put”, which is a level of pain that is reached that forces the Federal Reserve to step into the market and be a buyer of last resort * “The investments that one makes in this period will probably be the best for many many years to come because they’ll have the most asymmetric upside.” – Chamath Palihapitiya * The Federal Reserve, in conjunction with the last two administrations, printed $10 trillion over the last couple of years which has caused inflation to soar * There is $300T of global debt; if interest rates increase from 0% to 5%, that’s an increase of $15T in annual debt service, which is 18% of global GDP + Chamath sympathizes with Friedberg’s concerns over global debt but thinks perpetual bailouts will continue to negate the consequences of rising debt levels * The rate-setting process should leverage more of today’s technology; humans setting the rate in quarter-percent increments every couple of weeks seems archaic to Friedberg * “If you have these irrational central bankers that are willing to constantly bail people out, you will never get a high-functioning government because the policy is irrelevant.”– Chamath Palihapitiya * Europe slept-walked its way into WWI in 1914, which is something David Sacks thinks the United States could be doing today * David’s primary gripe inShould America Go All In On Ukraine is the U.S. media’s narrative that “Putin is bluffing”; we cannot know that he is definitely bluffing, and the stakes of being wrong are too high * Wealthy and powerful people in the U.S. might begin to put political pressure on their representatives to resolve the Russia-Ukraine issue because of the strain the conflict has placed on the markets and their portfolios * “I think that the markets would have reacted much much more negatively to a nuclear incident three months ago than now, and may not even react as much as we think it would three months from now.” – Chamath Palihapitiya on Sept. 30, 2022

Read the full notes @ podcastnotes.org

0:00 Bestie intros!

1:36 Big tech starts making cuts, plus what this means for the broader economy and startups

31:09 Global debt numbers, Fed incompetency

54:06 RIP Coolio

1:00:30 Russia / Ukraine update

Follow the besties:

https://twitter.com/chamath

https://linktr.ee/calacanis

https://twitter.com/DavidSacks

https://twitter.com/friedberg

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Intro Music Credit:

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Intro Video Credit:

https://twitter.com/TheZachEffect

Referenced in the show:

https://www.bloomberg.com/news/articles/2022-09-29/meta-announces-hiring-freeze-warns-employees-of-restructuring

https://www.google.com/finance/quote/META:NASDAQ

https://www.google.com/finance/quote/AAPL:NASDAQ

https://www.google.com/finance/quote/GOOG:NASDAQ

https://www.cnbc.com/2022/09/28/stanley-druckenmiller-sees-hard-landing-in-2023-with-a-possible-deeper-recession-than-many-expect.html

https://www.google.com/finance/quote/NFLX:NASDAQ

https://www.mckinsey.com/capabilities/mckinsey-digital/our-insights/if-youre-going-to-build-something-from-scratch-this-might-be-as-good-a-time-as-in-a-decade

https://www.forbes.com/sites/jonathanponciano/2021/05/11/billionaire-investor-druckenmiller-blasts-feds-radical-stimulus-policy-warns-it-risks-stock-bubble-blowing-up

https://www.cnbc.com/2022/09/28/cnbc-transcript-duquesne-family-office-chairman-ceo-stanley-druckenmiller-speaks-with-cnbcs-joe-kernen-live-during-the-cnbc-delivering-alpha-conference-today.html

https://www.xe.com/currencycharts/?from=GBP&to=USD&view=1M

https://www.bls.gov/charts/job-openings-and-labor-turnover/unemp-per-job-opening.htm

https://fred.stlouisfed.org/series/JTSJOL

https://www.wsj.com/articles/a-nation-of-quitters-great-enabling-exodus-working-age-men-parents-stimulus-covid-quit-retirement-bohemian-videogame-11664112795

https://goop.com/subscribe

https://www.reuters.com/world/putin-host-kremlin-ceremony-annexing-parts-ukraine-2022-09-29

https://www.reuters.com/world/europe/zelenskiy-says-ukraine-applying-nato-membership-2022-09-30

https://www.reuters.com/world/europe/qa-nord-stream-gas-sabotage-whos-being-blamed-why-2022-09-30

https://www.aa.com.tr/en/economy/former-polish-foreign-minister-thanks-us-for-damaging-nord-stream-pipeline/2696530

https://www.theamericanconservative.com/should-america-go-all-in-on-ukraine

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My First Million

Podcast Notes Key Takeaways * “You can learn good lessons from bad people.” – Sam Parr * Throw away your shame and embarrassment, fully commit to the bit, and you’re going to be really successful * Hitler, Napoleon, Caesar, and Jeff Bezos all took tons of resources and focused them on a very small point + This was Blitzkrieg for the Nazis and is Blitzscaling for the business world * Most successful people have addictive personalities; they are addicted to something, it just so happens that it is something positive * Highly successful people are likely born with a propensity to addiction * People born with a propensity to addiction could end up conquering a vast European empire or could get hooked on drugs and end up a junkie on the streets * Times of turmoil call for leaders who are mentally ill, whereas times of stability call for non-mentally ill leaders, according to author Nassir Ghaemi * Truly charismatic people make the people they interact with feel special * Many of the great dictators and CEOs were great orators; great orating starts with great writing * It’s tempting to obsess over planning and preparing when a bias towards measurable action oftentimes results in more success * Over planning is self-masturbation and a bullshit way to convince yourself that you’re actually doing something when instead you should just start and figure it out along the way * “It’s way better to execute a bad plan than to execute no plan.” – Sam Parr + Rookies should start their business today, generate $1 in revenue in the first five days, and get addicted to hearing the “cha-ching” sound from their Shopify store * In business, you don’t always need to know the math behind things, or why certain things work and certain things don’t; you just need to try stuff until you find out what works

Read the full notes @ podcastnotes.org

Episode 369: Sam Parr (@TheSamParr) and Producer Ben (@BenWilsonTweets) take a turn with One Question Friday... instead of a question they discuss traits of conquerors from yesterday and today.

Links:

My First Million
How To Take Over The World
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(02:25) - lessons from Hitler

(10:45) - lessons from Edison

(10:25) - addictive personalities

(18:10) - charismatic people

(26:25) - bias to action

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Econtalk

Podcast Notes Key Takeaways * Effective altruism involves billionaires creating various institutions to give away their money to charity in a manner they deem effective * Due to the core of the movement being utilitarian, the effective altruism movement ends up having many repugnant and strange conclusions * “Maximizing the most good for the most number of people” can lead to repugnant conclusions when applied at-scale * Changing the scale of these simple thought experiments adds complexities that completely change the calculus of the scenario + Not only should you not have the birthday party for your son, but you’re morally obligated to spend less time with your son so you can work more and send more money to help solve the malaria crisis in Africa * The repugnant conclusion of never-ending well-being arbitrage: everyone ends up with a life that is just barely above the subsistence level + Effective altruism wants to arbitrage all the extra happiness away and fairly distribute it amongst the global population * Trading instances of good and evil is not fungible in the way that utilitarians want it to be * The effective altruism movement is an attempt to formulate morality from the top-down, which is antithetical to how morals have emerged since the dawn of humanity * Utilitarianism treats good and evil as big mounds of dirt of varying sizes; Theoretically following the logic of utility, if enough people stub their toe over time, its respective pile of dirt could become larger than the pain-caused-from-WW2 pile of dirt * Economists often neglect qualitative components when forming policy and only account for the quantitative when making moral equivalencies, which results in bad policy * Charity is good; there are aspects of the effective altruism movement that are good, but the mandate to maximize it at scale deserves to be questioned and investigated

Read the full notes @ podcastnotes.org

Neuroscientist Erik Hoel talks about why he is not an "effective altruist" with EconTalk host, Russ Roberts. Hoel argues that the utilitarianism that underlies effective altruism--a movement co-founded by Will MacAskill and Peter Singer--is a poison that inevitably leads to repugnant conclusions and thereby weakens the case for the strongest claims made by effective altruists.

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Modern Wisdom

Podcast Notes Key Takeaways * Check out the Modern Wisdom Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Catherine Salmon is an evolutionary psychology researcher, professor of Psychology at the University of Redlands and an author.

Women can be a mystery, sometimes even to themselves. Modern culture is making many proclamations about what women like and why they should like it, but are these new headlines accurate, or even desirable?

Expect to learn why women love erotic stories so much, whether evolutionary psychology is sexist, why Catherine did a study where people rated the attractiveness of faces which had jizz on them, why feminine men are being pushed in media but don't feature in dark romance novels, the role of commitment in female attraction and much more...

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Extra Stuff:

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Get in touch.

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Huberman Lab

Podcast Notes Key Takeaways * Episodic therapy via deep brain stimulation delivered at the right time and only as needed at that time may be useful in treating obesity, addiction, and OCD to interrupt circuit dysfunction * Obesity is a phenotype often reflective of behavior – there’s a compulsion to overeat despite the risk * Development of eating disorders: (1) we’ve become a food-focused society – we’re really not meant to have constant stimulation of food; (2) there’s high fructose corn syrup in almost everything – processed foods rewire our circuitry to seek more; (3) recurring stressful event or life; (4) patients are embarrassed because society frowns on them * Right before people participate in binge eating, there’s a moment of feeling down or negative affect that they compensate for by binge eating or “loss of control eating” * Deep brain stimulation is currently being studied for use in binge eaters by provoking the craving during surgery and identifying the exact area of the nucleus accumbens where cravings occur – then delivering electrical stimulation * Anorexia, bulimia, and binge eating are all distortions in relationship to food where reward and habit are disrupted beyond control * Side note discussed: use power lifting and deadlifts specifically (with impeccable form, under supervision of trainer if needed) to profoundly improve strength & posture

Read the full notes @ podcastnotes.org

My guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern’s research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson’s disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement.

Thank you to our sponsors

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Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation

(00:03:18) ROKA, Eight Sleep, InsideTracker

(00:07:19) Momentous Supplements

(00:08:28) Neurosurgeon’s View of the Brain, Neurosurgery Specialization

(00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects

(00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies

(00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction

(00:31:11) AG1 (Athletic Greens)

(00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition

(00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity

(00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation

(00:49:49) Binge Eating Disorder & Loss of Control Eating

(00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress

(01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells”

(01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation

(01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia

(01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation

(01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson’s

(01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression

(01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation

(01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions

(01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts

(01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training

(02:09:53) Daily Habits: Sleep, Exercise, Mediation

(02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn

Title Card Photo Credit: Mike Blabac

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The Rational Reminder Podcast ✓

Claim

Podcast Notes Takeaways * Here is a summary breakdown of expected returns for alternative asset classes:

Read the full notes @ podcastnotes.org

The type of assets which usually come to mind when considering investments are stocks, bonds, or cash, but what are the alternatives? And what kind of returns do alternative asset classes offer? In today’s episode, we delve into the returns which can be expected from alternative asset classes such as private equity, venture capital, angel investing, private credit, hedge funds, direct real estate, and cryptocurrencies. Hear an in-depth analysis based on empirical studies and the expertise of your hosts, Ben and Cameron, to discover whether there is any merit to alternative asset classes as investments. We unpack the extra layer of complexity associated with predicting returns on alternative assets, how to approach calculating returns, and why the associated fees are an essential consideration. We also hear details about an interesting conference Cameron recently attended and briefly recap cryptocurrencies as an investment. You’ll also hear our conversation with our 22 in 22 reading challenge guest David Senra about his reading habits, the books that most inspire him, and his advice for people who want to read more.

Key Points From This Episode:

Outline of today’s main topic: expected returns for alternative asset classes. (0:01:51)
Why predicting returns of alternative asset classes has an extra layer of complexity. (0:03:18)
How to approach estimating the returns of private equity, specifically buyouts. (0:05:04)
We unpack historical data regarding the returns of private equity. (0:07:35)
Calculating the returns on venture capital and reasons to be cautious about it as an asset class. (0:16:35)
The distribution of returns from venture capital based on the market numbers. (0:20:09)
Learn what angel investing is and its associated returns. (0:20:54)
What returns on angel investing are most dependent on and why. (0:22:21)
The different types and the associated returns. (0:25:23)
Hear about the fees associated with private credit. (0:27:42)
We unravel the concept of hedge funds, the associated fees, and expected returns. (0:29:29)
A limiting factor on hedge funds: capacity constraints. (0:33:38)
The takeaway regarding private real estate investments. (0:36:25)
How private real estate is valued as an asset class. (0:37:48)
Cryptocurrencies and the returns to be expected. (0:39:34)
We discuss some of the key takeaways from today’s main topic. (0:43:30)
We follow up on a previous topic we covered: financial literacy. (0:45:10)
Find out about an interesting conference that Cameron recently attended. (0:48:46)
Hear about the recent reviews we have received about the podcast. (0:57:58)
We introduce our 22 and 22 reading challenge guest, David Senra. (01:00:15)
Where David’s passion for reading about founders originates from. (01:02:25)
David shares details about his reading habits. (01:05:57)
His approach to finding founders that he wants to read about. (01:08:49)
David’s approach to note taking while reading a book. (01:11:07)
We learn about the stories that have impacted David the most. (01:13:53)
He explains the benefits of reading a book for a second time. (01:17:11)
Books about founders that he thinks everyone should read. (01:19:20)
David’s observation of the role of luck in a founder’s success story. (01:23:19)
Advice he has for people who want to read more. (01:29:33)

Links From Today’s Episode:

AQR Capital Management — https://www.aqr.com/

BlackRock Asset Management — https://www.blackrock.com

Bank of America — https://www.bankofamerica.com/

‘The risk and return of venture capital’ — https://www.sciencedirect.com/science/article/pii/S0304405X04001564

‘Performance of Private Credit Funds: A First Look' — https://jai.pm-research.com/content/21/2/31.short

‘Do Hedge Funds Hedge?’ — https://jpm.pm-research.com/content/28/1/6.short

‘The Performance of Hedge Fund Performance Fees’ — https://www.nber.org/papers/w27454

‘Higher risk, lower returns: What hedge fund investors really earn’ — https://www.sciencedirect.com/science/article/abs/pii/S0304405X1100016X

‘Another Look at Private Real Estate Returns by Strategy’ — https://jpm.pm-research.com/content/45/7/95/tab-pdf-trialist

'The Characteristics and Portfolio Behavior of Bitcoin Investors: Evidence from Indirect Cryptocurrency Investments' — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3501549

‘Beliefs and the Disposition Effect’ — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3516567

‘Once Bitten, Twice Shy: The Power of Personal Experiences in Risk Taking’ — https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2506627

S&P Global FinLit Survey — https://gflec.org/initiatives/sp-global-finlit-survey/

Future Proof Conference — https://futureproof.advisorcircle.com/

Invest Like the Best Podcast — https://investlikethebest.libsyn.com/

David Senra on LinkedIn — https://www.linkedin.com/in/david-senra-278843236/

David Senra on Twitter — https://twitter.com/FoundersPodcast?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor

David Senra on Facebook — https://www.facebook.com/david.senra.1

The Founders Podcast — https://founders.simplecast.com/

A Triumph of Genius — https://www.amazon.com/Triumph-Genius-Edwin-Polaroid-Patent/dp/1627227695

Cable Cowboy — https://www.amazon.com/Cable-Cowboy-Malone-Modern-Business/

Titan — https://www.amazon.com/Rare-Chernow-Titan-Life-Rockefeller/

A Man for All Markets — https://www.amazon.com/Man-All-Markets-Street-Dealer/

Against the Odds — https://www.amazon.com/Against-Odds/

Estee: A Success Story — https://www.amazon.com/Estee-Success-Story-Lauder/

Rational Reminder on iTunes — https://itunes.apple.com/ca/podcast/the-rational-reminder-podcast/id1426530582.
Rational Reminder Website — https://rationalreminder.ca/

Rational Reminder on Instagram — https://www.instagram.com/rationalreminder/?hl=en

Rational Reminder on YouTube — https://www.youtube.com/channel/
Ben Felix — https://www.pwlcapital.com/author/benjamin-felix/

Ben on Twitter — https://twitter.com/benjaminwfelix

Ben on LinkedIn — https://www.linkedin.com/in/benjaminwfelix/

Cameron Passmore — https://www.pwlcapital.com/profile/cameron-passmore/

Cameron on Twitter — https://twitter.com/CameronPassmore

Cameron on LinkedIn — https://www.linkedin.com/in/cameronpassmore/

A Man for All Markets: From Las Vegas to Wall Street, How I Beat the Dealer and the Market

Cable Cowboy: John Malone and the Rise of the Modern Cable Business

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Knowledge Project

Podcast Notes Key Takeaways * When scaling a company: “You have to be constantly evolving your learning pattern. What got you here, won’t get you there.”– Reid Hoffman + Examples: how you organize your management (work vs management duties in each role), go-to-market strategy (how to get new sales), adjusting the cadence of hiring (promoting from within vs outside org) + This applies to our lives too, not just business! * Want to be a better leader?“Root for better angels on people”– Shane Parrish quoting Reid Hoffman + Make everyone the hero of their own story—people often don’t realize their own potential to make the world a better place * It’s timely and costly not to have a process for making fast decisions, here’s how to improve (continue reading for more detailed instructions): + Be an explicit leaner + Learn your set of decision-guiding questions + Identify irreversible consequences * You should never try to optimize opportunity cost to be 100% efficient + Some of your decisions will seem like an opportunity cost upfront but turn out to be one of your most valuable experiences + You must leave yourself some room for exploration and serendipity

Read the full notes @ podcastnotes.org

Few figures have shaped the way we think about business over the past 20 years more than Reid Hoffman. The co-founder of LinkedIn and former PayPal executive is also a wildly successful venture capitalist, author and podcaster, but he didn’t get to his place as a Silicon Valley giant without making plenty of crucial decisions. On this episode Hoffman discusses lessons learned from decades spent as a hands-on operator and investor, including what he knows about scaling that others miss, the three principles of decision making, how to constantly evolve your learning pattern, and why the best leaders adapt to the crisis at hand.

Hoffman is perhaps best known for co-founding the professional networking site LinkedIn, which he started in 2003 and later sold for a reported $26.2 billion to Microsoft in 2016. Prior to founding LinkedIn, Hoffman was one of the first employees at PayPal, where he served as an executive vice president. He is also a partner at the venture capital firm Greylock Partners, an investor in Airbnb, the author of a series of successful business books including Masters of Scale, and the host of the podcast of the same name.

Want to hear the entire episode with Reid Hoffman? Become a member today! Members get early access, hand-edited transcripts, member-only episodes, and so much more.

Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Modern Wisdom

Podcast Notes Key Takeaways * Check out the Modern Wisdom Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Gurwinder Bhogal is a programmer and a writer.

Gurwinder is one of my favourite Twitter follows. He’s written yet another megathread exploring human nature, cognitive biases, mental models, status games, crowd behaviour and social media. It's one of the best things I've read this year, so I just had to bring him on.

Expect to learn how bad things can sometimes feel better than good things, why people die on the hill of opinions they've only just begun believing, why intelligence plus ideology is a nightmare, how comedy can be a troll's last line of defence, the biggest lesson I learned from Joe Rogan, why regret minimisation should be a priority, why authoritarians lose sight of rationality and much more...

Sponsors:

Get over 37% discount on all products site-wide from MyProtein at https://bit.ly/proteinwisdom (use code: MODERNWISDOM)

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Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied)

Extra Stuff:

Check out Gurwinder's Substack - https://gurwinder.substack.com/

Follow Gurwinder on Twitter - https://twitter.com/G_S_Bhogal

Gurwinder's new MegaThread - https://twitter.com/G_S_Bhogal/status/1545510413982474253

Adam Mastroianni's post - https://experimentalhistory.substack.com/p/underrated-ideas-in-psychology

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Huberman Lab

Podcast Notes * “Nicotine is not the cause of cancer; nicotine is not the carcinogen. It’s the other things in tobacco or associated with the nicotine delivering device that are causing cancer and the other negative impacts on our health.” – Dr. Andrew Huberman * The state nicotine puts your body in is almost the optimal state for getting mental work done: you feel alert, focused, and able to concentrate – but at the same time, your body feels relaxed (this is the behavioral side of why it’s addictive) * Nicotine has 4 major effects of nicotine on the brain and neural circuits: (1) triggers the release of dopamine and increases levels; (2) increases attention, focus, and concentration (via an increase in acetylcholine); (3) increases alertness and arousal (net effect of an increase in epinephrine & norepinephrine); (4) appetite suppression * There is some evidence nicotine gum (not smoking, vaping, dipping, snuffing – those are never good) may increase cognitive performance * All methods of ingesting nicotine are not the same: vaping is the most dangerous and most addictive because of the speed and concentration at which it hits the bloodstream and the rapidness at which dopamine spikes (until you need more and more) * Why is it so hard to quit? The first week you stop, your dopamine is lower than baseline because you’re not giving your body & brain the hit it’s come to expect at a certain time so you feel much worse (remember the dopamine pleasure-pain balance) * Withdrawal sets in about 4 hours after the last smoke or vape – people wake up in nicotine withdrawal and immediately need nicotine * Tip to quit smoking: change the method of cessation each week to intermittently reward the dopamine system without expectation – start with the patch, then gum, then nasal spray

Read the full notes @ podcastnotes.org

In this episode, I explain how nicotine impacts the brain and body, including its potent ability to enhance attention, focus, and alertness, increase blood pressure and metabolism and reduce appetite. I discuss nicotine’s ability to increase the action of neurochemicals, including dopamine, norepinephrine, and acetylcholine and activate sympathetic (alertness-promoting) neural circuits. I also discuss common nicotine delivery methods, such as cigarettes, vaping, dip, and snuff, and how they each create their own unique experience and how they, but not nicotine itself, cause cancer and other adverse health effects. I also explain science-based tools to permanently quit smoking cigarettes or vaping, including peer-reviewed clinical hypnosis tools, antidepressants, and alternative nicotine replacement (patches, lozenges, gums etc.). As nicotine is one of the most widely used substances with billions of users — most of whom report wanting to quit — this episode ought to be of interest to former/current nicotine users, those who want to quit smoking or vaping and/or those interested in learning the biology behind how nicotine impacts the brain and body.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

ROKA: https://www.roka.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Nicotine

(00:02:47) Momentous Supplements

(00:03:41) Tool: Brief Daily Meditation & Focus

(00:05:59) The Arrow Model of Focus, Alpha GPC & Garlic Supplements

(00:10:43) Thesis, InsideTracker, ROKA

(00:14:35) Nicotine Effects vs. Methods of Delivery, Acetylcholine

(00:19:55) Where is Nicotine Found? Nicotinic Acetylcholine Receptors

(00:25:12) Nicotine & Effects on the Brain: Appetite, Dopamine & GABA

(00:30:58) AG1 (Athletic Greens)

(00:32:11) Nicotine, Acetylcholine & Attentional “Spotlighting”

(00:37:29) Nicotine, Norepinephrine & Alertness/Energy

(00:41:10) Nicotine & Effects on Appetite & Metabolism

(00:46:47) Nicotine & Effects on Body: Sympathetic Tone

(00:51:29) Nicotine & Cognitive Work vs. Physical Performance

(00:55:08) Nicotine Delivery Methods & Side Effects, Young People & Dependency

(00:58:35) Smoking, Vaping, Dipping & Snuffing: Carcinogens & Endothelial Cells

(01:02:34) Smoking, Vaping, Dipping & Snuffing: Negative Impacts on Lifespan & Health

(01:09:23) How to Quit Smoking, Nicotine Cravings & Withdrawal

(01:13:56) Vaping & Nicotine, Rates of Effect Onset, Dopamine, Addiction & Depression

(01:25:06) Tool: Quitting Smoking & Clinical Hypnosis, Reveri

(01:30:16) Bupropion (Wellbutrin) & Quitting Smoking

(01:36:24) Tool: A Nicotine Replacement Schedule to Quit Smoking, Nicotine Patch/Gum

(01:41:52) Tool: Biological Homeostasis & Nicotine Withdrawal, The “First Week” Strategy

(01:51:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook

Title Card Photo Credit: Mike Blabac

Disclaimer

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Honestly with Bari Weiss ✓

Claim

Podcast Notes Key Takeaways * The healthcare system is an engine designed to make money when more people are sick and remain in the system * We’ve gone far away from doctors actually restoring the health of the body as a whole and digging into its connectedness * We are flat out neglecting the root cause of disease – we’re eating 25x more refined sugar than we were 100 years ago, among many detrimental changes to our diet * “Right now, we are eating ultra-processed nutrient depleted crap.” – Dr. Casey Means * The social messaging has completely changed – instead of trying to prevent poor health and diseases that are within our control, we’re telling people there’s nothing wrong with being fat, your weight doesn’t matter, and foods are not ‘good’ or ‘bad’ * There’s substantial evidence today that chemicals in our food are “obesogens”, causatively lead to obesity – additives, and fillers such as microplastics, pesticides, coloring, and much more * Have no double about it – the healthcare system is a for-profit business; disease prevention & health would lose money * Success criteria in most hospitals: (1) in and out of exam room in 15 minutes; (2) new medication prescription; (3) charting that could be billed for; (4) rule out anything life-threatening; (5) patient is compliant with medication – notice the absence of improving health * “40% of the American Diabetes Association budget comes from pharmaceutical industries.” – Dr. Casey Means * Top tips to attaining better metabolic health: (1) eat real, unprocessed, clean food; (2) stick to the outsides of the grocery store where there are no processed foods; (3) get quality sleep; (4) manage stress; (5) move your body; (6) get sunlight; (7) avoid toxins in food and environmentally

Read the full notes @ podcastnotes.org

Fifteen years ago, there was a lot of talk about the obesity epidemic. In 2008, Michelle Obama started a government program called “Let’s Move!” that sought to reduce childhood obesity. You might remember the First Lady teaming up with everyone from Beyonce to Big Bird to promote exercise and better eating habits. Unfortunately, the program was largely a failure. And the obesity statistics continued to rise.

74% of Americans today are either obese or overweight. And yet, we’re no longer talking about it. The national conversation around health and weight has turned away from things like good nutrition, weight loss and the importance of physical fitness, and instead adopted phrases like “fat acceptance” and “healthy at any size.” In some circles, there’s even blanket denial that there is anything unhealthy at all about being obese.

Shaming people for being overweight is unequivocally wrong. But in our attempt to not offend, we’ve lost sight of the very real fact that there’s a problem. Americans are heavier than ever, sicker than ever, dying earlier than ever, and... it's all preventable. So today, a conversation with Dr. Casey Means, a Stanford trained physician who left the traditional medical system behind to solve the one problem that she says is going to ruin us all: bad food.

Learn more about your ad choices. Visit megaphone.fm/adchoices

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Artificial Intelligence Podcast

Podcast Notes Intro * Ray Kurzweil is an American inventor and futurist, who has been making (pretty accurate so far) predictions on the evolution of technology * In this conversation, Ray Kurzweil explores an optimistic future for our potentially inevitable merge with artificial intelligence * Become a Podcast Notes premium member to get the full notes * Host: Lex Fridman (@lexfridman)

Read the full notes @ podcastnotes.org

Ray Kurzweil is an author, inventor, and futurist. Please support this podcast by checking out our sponsors: – Shopify: https://shopify.com/lex to get 14-day free trial – NetSuite: http://netsuite.com/lex to get free product tour – Linode: https://linode.com/lex to get $100 free credit – MasterClass: https://masterclass.com/lex to get 15% off – Indeed: https://indeed.com/lex to get $75 credit EPISODE LINKS: Ray’s Website: https://kurzweilai.net Ray’s Books: The Singularity Is Nearer (pre-order): https://amzn.to/3BNXmGR How To Create A Mind: https://amzn.to/3qqlkBw The Singularity Is Near: https://amzn.to/3DfXP5z The Age of Spiritual Machines: https://amzn.to/3RSjtAX Danielle: https://amzn.to/3Bww2N7 Transcend: https://amzn.to/3RAEYGV PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS:

Transcend: Nine Steps to Living Well Forever

The Age of Spiritual Machines: When Computers Exceed Human Intelligence

The Singularity Is Near: When Humans Transcend Biology

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Behind the Tech

XKCD is one of our favorite webcomics - and it started out as doodles in Randall Munroe's college notebooks. Munroe describes his work as “a webcomic of romance, sarcasm, math, and language.” In this episode, he joins Kevin to talk about how he got started, where his inspiration comes from and his latest book, What If? 2: Additional Serious Scientific Answers to Absurd Hypothetical Questions. Find out why a surprising number of cartoonists are physicists by training, explore the joy of seeking answers to seemingly impossible questions, and much more!

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Pod of Jake

Podcast Notes Takeaways * Brian Armstrong felt like a failure when he was 28: all of his friends were making good money and had careers, and he was a failed entrepreneur * All of his “failures” contributed to his eventual successes when looking back with hindsight, but at the moment they only feel like failures * A heuristic for entrepreneurs unsure what to do: work on something that is the most interesting and most awesome thing to you * Technology is one of the greatest levers to improve the world, which includes money as a technology * Bitcoin is a technology that can inject economic freedom into countries all over the world * “Everything in business comes back to hiring great people.” – Brian Armstrong * Coinbase has taken a philosophy from Amazon.com called “Disagree and Commit”: even if you disagree with a decision that has been made, you must still work really hard to make it a success * Brian Armstrong borrowed the 70/20/10 resource allocation strategy from Google: spend 70% of resources on the core business, 20% on adjacent bets, and 10% on venture bets * Trying to change the world with policy and government intervention is inefficient and tends to create unintended consequences; it is better to change the world with science and technology * Asking the mainstream media to objectively cover the tech industry is like asking Pepsi for a fair review of Coca Cola * “The business section of the New York Times is basically an anti-business section.” – Brian Armstrong

Read the full notes @ podcastnotes.org

Brian is the Co-founder and CEO of Coinbase, a leading cryptocurrency company on a mission to increase economic freedom in the world. He is also a Co-founder of NewLimit, a biotechnology company working to radically extend human healthspan, and ResearchHub, which is aiming to accelerate the pace of scientific research. In 2018, Brian launched a nonprofit called GiveCrypto.org and signed the Giving Pledge, committing to give the majority of his wealth to charitable causes throughout his lifetime. Follow Brian on Twitter @brian_armstrong.

[2:18] - Brian's origin story

[9:33] - Reflections on his early career and how it prepared him to start Coinbase

[16:02] - Coinbase’s mission to increase economic freedom in the world, and why economic freedom is important

[23:34] - The challenges of building through crypto's hype cycles and scaling Coinbase at a rapid pace

[31:08] - An introduction to The RAPID Decision-Making Framework

[35:36] - How years of experience with remote employees helped Coinbase become a remote-first company

[45:24] - Repeatable innovation and the rationale for Coinbase’s 70/20/10 strategy for resource allocation

[54:34] - Coinbase’s contrarian decision to work with regulators from the beginning, and how it is increasingly leaning in on decentralization

[1:03:38] - Extending the human healthspan, an overview of NewLimit, and epigenetic reprogramming

[1:15:25] - Prioritizing "new media" over mainstream media

[1:21:12] - How ResearchHub can enable more open science and help build a bridge from scientific research to commercial products

Support the show by checking out my sponsors:

Join Levels and get personalized insights to learn about your metabolic health. Go to https://levels.link/jake.

https://homeofjake.com

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My First Million

Podcast Notes Intro * Sam Parr (@thesamparr) is an American businessman and podcaster co-hosting the My First Million podcast. He is best known for founding The Hustle Media Production company and selling it to HubSpot for an estimated $27 million. * Shaan Puri (@ShaanVP) is an entrepreneur, investor, and co-host of the My First Million podcast. He shares insights and frameworks on his website and newsletter, which has +30K subscribers. * In this conversation, Sam and Shaan field six pitches from founders trying to raise capital for their respective startups. This is My First Million meets Shark Tank! * Check out these Podcast Notes from Sam and Shaan’s conversation with the guy that bought Sam’s company

Read the full notes @ podcastnotes.org

Episode 356: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) with the help of Stonks.com , listen to six entrepreneurs pitch their business in hopes of getting Shaan and Sam to invest.

To watch this podcast, head over to our YouTube channel: https://youtu.be/OKI1X1qFgwg

Links:

Cherry
Pillup
Campus Ink
Terrashroom
Dealbuilder
Field Complete
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(05:35) - Luke @ Cherry

(17:40) - Ankur @ Pillup

(30:05) - Steven @ Campus Ink

(42:45) - Jared @ Terrashroom

(54:10) - Morgan @ Dealbuilder

(01:04:05) - Tim @ Field Complete

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Mark Pesce - The Next Billion Seconds ✓

Claimed

Podcast Notes Key Takeaways * The United States does not have a great history of exporting things to countries before conflicts happen * “The big defense primes are not in the position to build the right things, partly because the government has created the wrong incentives for them to do so.” – Palmer Luckey * “The point of high-end defense technology is not to win a war that has already started; it’s to deter that war from happening, to make the cost of engaging in that war so high that it never happens.” – Palmer Luckey * “The real reason that these tech companies were not doing work with the United States military, or foreign allied militaries, was that they were afraid of upsetting China.” – Palmer Luckey * Until Anduril became the third unicorn in 2019, there were only two unicorns in the defense industry since the Cold War: Palantir and SpaceX * It took billionaire-founders with previous success starting companies for venture capitalists to invest in the defense industry * Russia’s invasion of Ukraine forced many venture capitalists to reconsider their assumptions about investing in defense tech * Some countries are willing to do irrational things that disrupt their economic relationships with other countries; irrational wars and conflicts are prevalent throughout history * “I think the odds of a direct, hot war between the U.S and China are very very low. I think the odds of a proxy conflict over minerals in South America, South Africa, or Southeast Asia are quite high.” – Palmer Luckey * Anduril is the answer to the question: “What would a next-generation Lockheed Martin look like?” * Without giving away Anduril’s entire roadmap, the future of defense will have a lot of autonomous things across air, land, sea, subsea, and space all working together * Palmer is more concerned about evil people using very basic AI than extremely advanced AI taking over the world in a Skynet scenario * The U.S. must be involved in the technology (nuclear, autonomous weapons, etc.) if it wants to lead and potentially regulate how those technologies are used in the rest of the world * “I want to save taxpayers hundreds of billions of dollars a year while we [Anduril] make tens of billions of dollars a year.” – Palmer Luckey

Read the full notes @ podcastnotes.org

In this live interview with Oculus and Anduril founder Palmer Luckey - joined by Anduril Chief Engineer Shane Arnott - we look at the future of defense, geopolitics, and Australia's future in a transformed Indo-Pacific region. Have we shifted toward a defense-driven future? For more information about this and all our other Next Billion Seconds content, please check out https://nextbillionseconds.com

Mark Pesce - The Next Billion Seconds is produced by Ampel - visit https://ampel.com.au to find out what Ampel could do for you! If you are interested in sponsoring The Next Billion Seconds podcast, reach out to our Director of Media and Partnerships Lauren Deighton at lauren@ampel.com.au If you enjoyed this show, please leave a rating and/or review on Apple, Spotify or any other podcast platform.

See omnystudio.com/listener for privacy information.

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Pomp Podcast

Podcast Notes Key Takeaways * A balanced life has its advantages, but you can’t get exceptionality if you prioritize balance above all else * Crackheads that get clean often replace their addiction to crack with something else; channeling their addictive personality towards something productive is life-changing * Most people choose the more comfortable option of “doubling down on their own world” instead of venturing into worlds that are foreign to them * People around you will forgive you – probably more than they should – when you commit to improving your life and are serious about it over a long period of time * People from all walks of life can have extremely similar experiences, and yet they appear to be different based on surface-level interpretations of those experiences, language used to describe them, etc. + Synthesizing insights from two different perspectives is not 1+1=2, but 1+1=7 * “There is someone out there with half your IQ, that is accomplishing 10x what you are because they’re not smart enough to doubt themself.” – Ed Latimore * The people that get far are the ones that embrace what scares them * The sum of the world’s knowledge is at your fingertips; you just need to learn the skill of asking the right questions * Immense innovation tends to happen on compressed timelines, and then large amounts of time can pass before the next rapid period of innovation ensues

Read the full notes @ podcastnotes.org

Ed Latimore is a former heavyweight boxer, best-selling author, and chess enthusiast.

In this conversation, we discuss the crackhead work theory, Ed's recovery from alcohol addiction, why the world has gone so crazy, critical thinking, and narrative violations in recent years.

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Bullish is a powerful new exchange for digital assets that offers deep liquidity, automated market making, and industry-leading security. Combining the innovations of DeFi with the regulated environment of traditional finance, Bullish empowers users to trade with certainty and earn passively at scale across variable market conditions, in an environment backed by multibillion-dollar liquidity contributions from the Bullish Treasury. Visit bullish.com/pomp today to learn more.

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Valour (formerly DeFi Technologies) represents what’s next in the digital economy -- providing simplified, trusted access to crypto, decentralized finance and Web 3.0 investment opportunities. Institutions and investors can gain diversified, secure, compliant, and easily tradable access to a diversified set of industry-leading equity products and protocols, through a single stock purchase on a regulated exchange.

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If you’re trying to grow and preserve your crypto-wealth, optimizing your taxes is just as lucrative as trying to find the next hidden gem.Alto IRA can help you invest in crypto in tax-advantaged ways to help you preserve your hard earned money.

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Huberman Lab

Podcast Notes * The areas of the brain that control feeding, fleeing, fighting, and mating are in close proximity in the brain possibly to help the animal decide what behavior to prioritize and what to shut down at any given moment * “Aggression refers more to a description of behavior than the internal state. Aggression could reflect fear, anger, hungry (in animals).” – Dr. David Anderson * Estrogen and the aromatase of testosterone into estrogen is really what generates aggression, not testosterone alone * Arousal is tethered to the mating and reproductive process: without a seesaw between sympathetic and parasympathetic, there is no mating * The same behavior can reflect different states and different states can converge on multiple behaviors * In social animals and humans, the body secretes higher levels of tachykinin when we are not socially connected enough – symptoms: increased irritability, paranoia, fear, loneliness * Emotion involves bidirectional communication between the brain and body, mediated by the peripheral nervous system, autonomic nervous system, and Vagus nerve

Read the full notes @ podcastnotes.org

My guest is David Anderson, PhD, a world expert in the science of sexual behavior, violent aggression, fear and other motivated states. Dr. Anderson is a Professor of Biology at the California Institute of Technology (Caltech), a member of the National Academy of Sciences and an investigator with the Howard Hughes Medical Institute (HHMI). We discuss how states of mind (and body) arise and persist and how they probably better explain human behavior than emotions per se. We also discuss the many kinds of arousal that create varying levels of pressure for certain behaviors to emerge. We discuss different types of violent aggression and how they are impacted by biological sex, gender, context, prior experience, and hormones, and the neural interconnectedness of fear, aggression and sexual behavior. We also discuss peptides and their role in social isolation-induced anxiety and aggression. Dr. Anderson also describes novel, potentially powerful therapeutics for mental health. This episode should interest anyone wanting to learn more about mental health, human emotions, sexual and/or violent behavior.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

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Dr. David Anderson

The Nature of the Beast

Dr. David Anderson’s Lab

Dr. Anderson’s publications

Articles

Two Different Forms of Arousal in Drosophila Are Oppositely Regulated by the Dopamine D1 Receptor Ortholog DopR via Distinct Neural Circuits

Resources

Mouse switching from mating behavior to aggressive behaviors upon stimulation of VMH

VMH stimulation causes mouse to display aggressive behaviors toward an inanimate object (e.g., glove)

Picture of Periaqueductal Gray (PAG)

Timestamps

(00:00:00) Dr. David Anderson, Emotions & Aggression

(00:03:33) Momentous Supplements

(00:04:27) Levels, Helix Sleep, LMNT

(00:08:10) Emotions vs. States

(00:10:36) Dimensions of States: Persistence, Intensity & Generalization

(00:14:38) Arousal & Valence

(00:18:11) Aggression, Optogenetics & Stimulating Aggression in Mice, VMH

(00:24:42) Aggression Types: Offensive, Defensive & Predatory

(00:29:20) Evolution & Development of Defensive vs. Offensive Behaviors, Fear

(00:35:38) Hydraulic Pressures for States & Homeostasis

(00:38:33) AG1 (Athletic Greens)

(00:39:46) Hydraulic Pressure & Aggression

(00:44:50) Balancing Fear & Aggression

(00:48:31) Aggression & Hormones: Estrogen, Progesterone & Testosterone

(00:52:33) Female Aggression, Motherhood

(00:59:48) Mating & Aggressive Behaviors

(01:05:10) Neurobiology of Sexual Fetishes

(01:10:06) Temperature, Mating Behavior & Aggression

(01:15:25) Mounting: Sexual Behavior or Dominance?

(01:20:59) Females & Male-Type Mounting Behavior

(01:24:40) PAG (Periaqueductal Gray) Brain Region: Pain Modulation & Fear

(01:30:38) Tachykinins & Social Isolation: Anxiety, Fear & Aggression

(01:43:49) Brain, Body & Emotions; Somatic Marker Hypothesis & Vagus Nerve

(01:52:52) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips

Title Card Photo Credit: Mike Blabac

Disclaimer

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IMPACT SHOW ✓

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(for EPISODES 39 - 41, visit the IMA YouTube channel)

Author of Fossil Future, Alex Epstein, shares his expertise and philosophical perspective on climate, energy and fossil fuels. Watch as Entrepreneur Peter Thiel and Epstein dive deep into the truths and arguments behind what most people may think is insane. Learn from these experts what is in the future for technology, inflation, climate and why it is okay to be optimistic even in these trying times.

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School of Greatness

Podcast Notes Key Takeaways * Check out The School of Greatness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Alex Hormozi is a first generation Iranian-American entrepreneur, investor, and philanthropist. In 2013, he started his first brick & mortar business, successfully scaling his business to six locations in three years. From there, he spent two years turning 32+ brick & mortar businesses around using the same model that made his privately owned locations successful. In total, He has scaled and exited 7 companies. His most notable exit was his majority sale of his licensing company for $46.2M in 2021. Concurrently in 2020, he transitioned from CEO to the owner/shareholder position in these companies and founded Acquisition.com as a way to invest his own wealth (both monetary and intellectual capital) into other businesses.

Buy his book: $100M Offers: How To Make Offers So Good People Feel Stupid Saying No

In this episode, you will learn:

The single most significant differentiator of rich and poor
How to sell someone who has no reason to sign up and enroll them in your purpose
The importance of respect in a healthy marriage
The main mistake most people make with sales

For more, go to: lewishowes.com/1296

Alex's previous episode:https://link.chtbl.com/1278-pod

The Biggest Lies You've Been Told About Money, Debt & Building Wealth w/ Jaspreet Singh (Minority Mindset): https://link.chtbl.com/1257-pod

Scooter Braun On Healing Past Trauma, Building A Business Empire & Finding Peace: https://link.chtbl.com/1244-pod

$100M Offers: How To Make Offers So Good People Feel Stupid Saying No

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Huberman Lab

Podcast Notes * Epinephrine/adrenaline, acetylcholine, and dopamine work together to facilitate the ability to get focused, direct focus, and stay focused over time * Binaural beats (40 Hz), white noise, pink noise, and brown noise can enhance focus & more importantly, decrease the amount of time it takes to get into a focused state by ramping up neurochemicals * Blocking time: use ultradian cycles (90-minute bouts) for intensely focused sessions; assume it will take about 5-10 minutes to ease in and then ramp up; when finished, spend 10-30 minutes to deliberately defocus * Both things are true: fasted states and fed states (sufficient glucose but not overly stuffed belly) stimulate neuronal activity – leverage this and try one focused 90-minute bout in the morning (fasted) and another in the afternoon (fed) * Tip: leverage benefits of stress through cold exposure – try a cold shower (uncomfortably cold but safe to stay in) 1-5 minutes to increase epinephrine and dopamine in the brain and body to get the body into a focused state – the positive effects of epinephrine last up to an hour or more * Focus will drift unless you are an experienced meditator – the most important component of meditation is refocusing back to meditation and back to the breath – try 13 minutes per day * Meditation caveat: focused meditation in the 4 hours prior to bed actually hindered the ability to fall asleep and stay asleep * Using visual field to improve focus: set a timer for 30 seconds per day and try to focus on one object; keep adding 5 seconds per day looking directly at the location (be sure to blink!) – you can use this to help onramp into 90-minute focused bout * As always, start with behavioral tools (and dialing in sleep), then focus on nutrition, try supplementation – when all else fails and you’ve consulted a doctor, lean on prescription drugs * Really sleep-deprived or having trouble focusing? Stack tools – for example, take a cold shower, leverage the visual field, and take alpha-GPC

Read the full notes @ podcastnotes.org

In this episode, I provide a list of behavioral, nutritional, and supplement-based tools you can use to improve your ability to get into a focused state to do mental or physical work. I explain science-supported strategies for transitioning into focus, maintaining focus during the work bout, and exiting the focus session, which is also critical, including decompression/defocusing tools. I explain when and how to use: binaural beats, caffeine, deliberate cold exposure, the pros and cons of working in fasted vs. fed states, and supplements and foods that enhance dopamine, epinephrine (i.e., adrenaline) and acetylcholine to promote optimal focus. Also, I explain how short behavioral practices, such as meditation and visual gaze training, will benefit your ability to focus over the long term. As deep focus is crucial to significantly improve cognitive or physical performance in any realm, this episode should be useful to anyone. By the end, you’ll have an essential toolkit of science-supported, low- to zero-cost focus and concentration strategies to select from that can be tailored to your physical and mental performance needs.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

LMNT: https://drinklmnt.com/huberman

Eight Sleep: https://www.eightsleep.com/huberman

Virtusan: https://virtusan.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Focus Toolkit

(00:04:25) Momentous Supplements

(00:05:38) Thesis, LMNT, Eight Sleep

(00:09:37) The “Arrow Model” of Focus: Epinephrine, Acetylcholine & Dopamine

(00:15:15) Modulation vs. Mediation, Importance of Sleep

(00:18:11) Tool: Binaural Beats to Improve Concentration

(00:20:54) Tool: White, Brown & Pink Noise, Transition to Focused State

(00:22:55) Warm-Up for Cognitive Work, Refocusing Attention & Neuroplasticity

(00:26:14) Tool: Ultradian Cycles: Warm-Up, Maintaining Focus & Deliberate Defocusing

(00:31:22) How Many Daily Ultradian Cycles Can One Perform?

(00:34:14) AG1 (Athletic Greens)

(00:35:35) Virtusan: Mental & Physical Health Journeys

(00:36:52) Tool: Fasted vs. Fed States & Focus, Prevent an Afternoon Crash, Ketosis

(00:45:52) Tool: Foods to Improve Focus & Regulating Food Volume

(00:47:53) Tool: Caffeine & Focused Work, Dopamine Efficacy, Alertness

(00:52:55) Tool: Stress & Improved Concentration

(00:55:46) Tool: Deliberate Cold Exposure & Focus, Dopamine & Epinephrine

(01:00:39) Layer Focusing Tools & Design Your Own Protocols

(01:01:19) Tool: Short Meditation & Improved Ability to Refocus

(01:07:40) Tool: Yoga Nidra, Non-Sleep Deep Rest (NSDR) & Defocus Periods

(01:12:13) Tool: Hypnosis & Focus/Deep Relaxation States

(01:16:07) Optimal Time of Day to Use Specific Tools

(01:16:46) Tool: Overt Visual Focus & Deliberate Gaze

(01:20:42) Covert Visual Focus; Deliberate Gaze Warm-Up & Focused Work

(01:24:43) Tool: Omega-3 Essential Fatty Acids

(01:27:28) Tool: Creatine Monohydrate

(01:29:10) Tool: Alpha-GPC & Acetylcholine, Increased Risk of Stroke? & Garlic

(01:33:52) Tool: L-Tyrosine Supplements & Food

(01:34:47) Combining & Choosing Focus Tools, Variability

(01:36:50) ADHD Prescriptions, Training Neural Circuits, Maintenance & Reduced Dosage

(01:39:19) Tool: Optimal Order Approaching Focus Tools, Prescriptions & Dependency

(01:42:56) Tool: Phenylethylamine & Dopamine

(01:44:50) Tool: Other Supplements to Enhance Dopamine, Epinephrine & Acetylcholine

(01:46:46) Behavioral, Nutrition & Supplement Tools for Focus

(01:49:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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Modern Wisdom

Podcast Notes Key Takeaways * Have a vector that orients your time, attention, and energy towards achieving your goal, and allow for subroutines to develop off of that vector that get you closer to your goal * Design an information diet like you would design your diet with food: this information is good, this information is bad, don’t consume this type of information, only consume this type of media during this specific time of day, etc. * Failing restaurants add sugar to their meals as a last-ditch effort to attract patrons back to their restaurant, and the legacy media does the same with information * Twitter is the public war zone; it is the new parliament where ideas are shared and challenged, and it’s actually upstream of governments + You can learn a lot from Twitter by following interesting people and accounts, but it is easy to overdose on the serendipity of it * “What thesmartest people do on the weekends is what everyone else will do during the week in 10 years.” – Chris Dixon * Technologies that Balaji is interested in today: digital nomadism, a “full crypto life”, AI content creation, and synthesis search engines * Wars fought today will not look like wars fought in the past; they will include terrorism, social media memes, hacks, de-platforming, assassination, and more + The new form of war is better because it’s less destructive to property, but it’s worse because the battlefield is everywhere and nowhere * America’s conflict won’t be blue vs. red, it will be green vs. orange, or at a higher level: centralization vs. decentralization * “I am not very confident in America’s hard power in a serious fight with China in its own backyard because America is overconfident.” – Balaji Srinivasan * Russia cannot give up on Ukraine; China cannot give up on Taiwan; America can and probably will give up on Ukraine and Taiwan like it gave up on Afghanistan * The resolution of the government’s war with Big Tech is to effectively nationalize Big Tech, regardless of the justification, and it will justify its measures in the name of combatting Chinese Control * Choosing betweenAmerican Anarchy and Chinese Control is not ideal for most countries or most people * The Cold War had a “third world” consisting of non-aligned countries with neither the U.S. nor the Soviets, but it was significantly behind the U.S. and Soviet blocs + Balaji thinks a third group could emerge in the America-China conflict, but perhaps this time, it comes in first because of the modern technologies that empower the individual

Read the full notes @ podcastnotes.org

Balaji Srinivasan is an entrepreneur and essayist, he was co-founder of Counsyl, former chief technology officer of Coinbase and former general partner at Andreessen Horowitz.

Our information diets are making us mentally fat. Whether it's fake news, mis or disinformation, state propaganda or conspiracy theories, the world is very difficult to navigate. Balaji also wants to start a new type of country, he has views on how to optimise your working day and he generates more new ideas than almost anyone. Today we get an insight into his thought process behind all of this.

Expect to learn why socialism always continues to arise across the world, how Balaji tracks all of the ideas he has in his head, why Singapore is a powerhouse of a new country, how immigration will deal with remote VR workers in India, why everyone should use a dashboard to track what's going on in their life, the key trick that the legacy media uses to manipulate you and much more...

Sponsors:

Get $100 off plus an extra 15% discount on Qualia Mind at https://neurohacker.com/modernwisdom (use code MW15)

Get the Whoop 4.0 for free and get your first month for free at http://join.whoop.com/modernwisdom (discount automatically applied)

Get a Free Sample Pack of all LMNT Flavours at https://www.drinklmnt.com/modernwisdom (discount automatically applied)

Extra Stuff:

Read The Network State - https://thenetworkstate.com/

Check out Balaji's website - https://balajis.com/

Follow Balaji on Twitter - https://twitter.com/balajis

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

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Email: https://chriswillx.com/contact/

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * With the help of artificial intelligence, neural networks, and computer engines, the chess playing field is much more level + How to win in today’s game: Since “the best moves have been analyzed to death,” surprising your opponent is the greatest advantage—sacrifice the optimal in favor of the unexpected. * In a World Championship setting, the fear of losing is more motivating than the love of winning + “Being World Champion has been a core part of my identity for a while, so there’s not an option of losing that” – Magnus Carlsen + Magnus is not participating in the next World Championship because he doesn’t like that relief is the first emotion he feels after winning (rather than joy) + But he takes more pride in his #1 rating (since the Summer of 2011) than his World Championships anyway * Magnus doesn’t actually practice chess, he just researches and visualizes + He is the best in the world at evaluating the board and calculating the next few moves in real time + Evaluation = all pieces are in harmony with optimal placement and your accumulating small advantages * Different ways chess translates to life: + Chess sharpens your decision-making by increasing your ability to make informed guesses in a limited amount of time + Doing nothing is often a much better strategy than doing something – “You have a choice: in certain situations, you should not try to win, you should just let your opponent lose” – Magnus Carlsen

Read the full notes @ podcastnotes.org

Magnus Carlsen is the highest-rated chess player in history and widely considered to be the greatest chess player of all time. Please support this podcast by checking out our sponsors: – Shopify: https://shopify.com/lex to get 14-day free trial – Athletic Greens: https://athleticgreens.com/lex to get 1 month of fish oil – Fundrise: https://fundrise.com/lex – BetterHelp: https://betterhelp.com/lex to get 10% off – InsideTracker: https://insidetracker.com/lex to get 20% off EPISODE LINKS: Magnus’s Twitter: https://twitter.com/MagnusCarlsen Magnus’s Instagram: https://instagram.com/magnus_carlsen Magnus’s YouTube: https://youtube.com/c/themagnuscarlsen Magnus’s Website: https://magnuscarlsen.com PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT

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Tales from the Crypt: A Bitcoin Podcast

Join Marty as he sits down with Lord Miles to discuss traversing Afghanistan during a time of war. They also discuss the aftermath of visiting countries under sanctions, the global spring upon us and just how fake news coverage by the mainstream is perpetrated.

Follow Lord Miles on Twitter

Learn more about Lord Miles Routledge Adventures

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Modern Wisdom

Podcast Notes * Ways to safely add friction to your life & raise stress threshold to enhance your ability to stay calm under pressure: cold shower, ice bath, cyclic hyperventilation – stress grows you * Grief is a motivated state of being highly alert but very sad, where we try to bridge the space and time of a loved one but it’s impossible since that person is gone – the brain has to confront the reality that someone is gone * The ability to feel the feelings helps you move through a breakup: women reportedly experience higher levels of emotional pain during a breakup but recover more fully over time; men rarely fully recover * If we expose regularly expose ourselves to things that trigger high levels of dopamine release, we will actually lower our baseline levels of dopamine over time * To maintain high levels of motivation, try intermittent rewards: celebrate successes every other time, every tenth time, etc. to blunt dopamine response, prevent crashes, and keep you on the path to bigger goals * Lessons from Lex Fridman: There are a lot of energy pits but success is really about not allowing energy to dissipate into negative trails (e.g., fighting people online, cynics, etc.) * Evolutionarily, mating is a test as to whether two people can coordinate autonomic nervous systems * Actual + perceived = reality: any event causes a real physiological response, but that response is entangled with our expectation of what the response should be * Tap into whatever eating system works for you – but one thing is true, consistency helps anchor your sleep schedule * Light, exercise, and temperature (hot and cold) are potent stimuli for creating hormonal and neuromodulator effects – it works the first time and every time

Read the full notes @ podcastnotes.org

Dr Andrew Huberman is a neuroscientist, Associate Professor at the Stanford University School of Medicine and a podcaster.

The mind and the body are intimately linked. Trying to improve your mental outcomes without thinking of your physical inputs is a losing battle, but the question of which inputs to use, and when is a huge challenge. Thankfully, Dr Huberman is one of the best communicators of high performance advice on the planet and has a lot of answers.

Expect to learn the neuroscience of getting over your ex, how David Goggins trained himself to lean into fear, whether dopamine detoxing really works, the most important things to avoid doing during your morning routine, just how worried we should be about men's testosterone levels dropping, what everyone can learn about endurance from Lex Fridman, why Andrew doesn't show his tattoos and much more...

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Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/

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Get 20% discount on Impossible’s sleep powder at https://impossible.co/modernwisdom (use code: MW20)

Get 10% discount on your first month from BetterHelp at https://betterhelp.com/modernwisdom (discount automatically applied)

Extra Stuff:

Check out the Huberman Lab Podcast - https://hubermanlab.com/

Follow Dr Huberman on Instagram - https://www.instagram.com/hubermanlab/

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Twitter: https://www.twitter.com/chriswillx

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Email: https://chriswillx.com/contact/

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Pomp Podcast

Podcast Notes Key Takeaways * The rancher loses control over what is done to his cow once it leaves his farm; the packers, feeders, and processors, who make up the feed-lot apparatus, can feed the cow grains and inject it with antibiotics and steroids + Ranchers can no longer take the cow from the farm to the end-consumer’s fork because of regulatory capture * The United States grows and processes the best beef in the world, but the beef is sold to the highest bidder in the global market, so much of it is exported out of the U.S. * Much of the beef that people consume in the U.S. is imported from places like Brazil and Africa and has a worse nutritional profile than beef that’s produced in the U.S. * America’s health began to deteriorate in 1971 when highly processed foods were introduced into the food supply + This was the same year that the U.S. dollar was originally debased * The high production of monocropping has destroyed our soil, and to compensate for the destroyed soil, we have been forced to genetically modify our seeds and use new chemicals to make our plants grow * The same chemical companies that invented Agent Orange invented Roundup, which is glyphosate * Glyphosate is poisonous to humans and the soil, and it is sprayed all over our food * Following President Eisenhower’s heart attack in 1954, and Ancel Keys’ subsequent blaming of the heart attack on the president’s consumption of animal fat, chemical companies lobbied to rid human diets of animal fats so they could profit from creating the replacement to animal fats * … * The same thing that was done with seed oils will be done with animal protein; they will turn alternative vegetable protein sources into large consumption commodities, such as pea protein, cricket, soy, scorpions, etc. + … * Testosterone levels in men are about 50% less in 2020 than they were in 2000

Read the full notes @ podcastnotes.org

Texas Slim is the Founder of 'The Beef Initiative" and "Food Intelligence"

In this conversation, we talk about everything that's wrong with our current food supply today. Some of these topics include seed oils, the beef supply system, why market access has become so difficult, declining testosterone levels, the food being served to our children in school, obesity, fake meat propaganda, and how the decline in food quality matches up with the decline in U.S. Dollar over the past generation. This is a must listen if you want to get informed about providing you and your family with the proper food supply needed for a healthy life.

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Valour (formerly DeFi Technologies) represents what’s next in the digital economy -- providing simplified, trusted access to crypto, decentralized finance and Web 3.0 investment opportunities. Institutions and investors can gain diversified, secure, compliant, and easily tradable access to a diversified set of industry-leading equity products and protocols, through a single stock purchase on a regulated exchange. Currently listed on U.S. (OTC: DEFTF) and Canadian (NEO:DEFI) exchanges.

For more information or to subscribe to receive company updates and financial information, visit our website at valour.com

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If you’re trying to grow and preserve your crypto-wealth, optimizing your taxes is just as lucrative as trying to find the next hidden gem.Alto IRA can help you invest in crypto in tax-advantaged ways to help you preserve your hard earned money. Alto CryptoIRA lets you invest in more than 200 different coins and tokens with all the same tax advantages of an IRA.They make it easy to fund your Alternative IRA or CryptoIRA via your 401(k) or IRA rollover or by contributing directly from your bank account.

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Found My Fitness - Rhonda Patrick

Podcast Notes Key Takeaways * CRISPR is a subset of editing; editing is a subset of genome engineering; genome engineering is gene therapy * “Shrinking our agricultural use, possibly by 10 or 100 fold is feasible to do with synthetic biology and other new tools.” – Dr. George Church * Advances in reading and writing DNA double at least once per year; most of the exponential increase has occurred in the last 10-20 years * Cons of synthetic biology: lack of equity in access to technology and treatments; head in the sand approach to new technologies – FDA does not review; ethical considerations * Preventive medicine in genetics: genetic counseling preconception would be helpful to understand the future of offspring (as opposed to spending millions over a lifetime in gene therapy if disease is present) * Aging studies in dogs (as opposed to rodents) are good parallel to outcomes in humans because they’re large, live in human environments, have similar emotions, and bonding * “What’s natural is a moving target – a lot of things that were demonized or villainized in the past are now taken for granted, for example, some of us might remember how cell phones with were demonized as melting your brain or getting radiation to your brain.” – Dr. George Church * Gene editing therapy has the potential to reduce medical load, improve agriculture, alleviate some poverty burden (if there’s less disease), eliminate disease animal-human transmission, eliminate or reduce germline disease * There is no way to have zero risk – status quo is risky, but we should start small in animal studies and then progress to human studies

Read the full notes @ podcastnotes.org

George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.

In this episode, we discuss:

07:13 - History of the Human Genome Project
15:20 - Manufacturing cell phones (with biology)
17:34 - Genome Project-Write
20:03 - Writing a human Y chromosome (from scratch)
20:48 - What if you could eliminate viral disease?
22:51 - De-extinction and reinstating lost traits and genes
27:06 - The Vertebrate Genomes Project
29:47 - AlphaFold and other AI tools
41:27 - CRISPR vs. Base Editing (emerging tools of genetic engineering)
49:40 - Why multiplex editing will change the world
52:18 - Molecular flight recorder
53:31 - Preventing viral spillover and enhancing livestock
57:40 - PCSK9 gene therapy for cholesterol
01:00:30 - Is aging an evolved program?
01:05:21 - Treating aging with a combination gene treatment
01:09:04 - Does animal research help us understand human aging?
01:11:40 - Human organoids as a model and therapeutic
01:13:34 - Could engineered transplant organs become better than the originals?
01:16:17 - Embryo editing controversy
01:28:41 - Gene editing for space travel
01:30:40 - Can synthetic biology alleviate poverty?
01:34:07 - Is in vitro fertilization and embryo selection practically similar to editing?
01:39:12 - The occasional cost of brilliance
01:45:45 - Eradicating disease with Gene Drive
01:48:55 - Technologies to solve Lyme disease
01:51:57 - Dr. Church's experience with narcolepsy as a bridge to creative insights
02:00:42 - Why George encoded his book in DNA

Watch this episode on YouTube

Show notes are available by clicking here

Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter

Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/premium

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Huberman Lab

Podcast Notes * “Learning how to produce speech is a more complex learning ability than say learning how to walk or do tricks and jumps that dogs do.” – Dr. Erich Jarvis * Only vocal-learning (ability to imitate sounds) species can learn how to dance * Humans have a striking similarity to songbirds in terms of function, structure, and genome of language * Humans use our voices for semantic, abstract communication but we use learned to dance for effective emotional bonding communication * When you write something out, you’re speaking it to yourself in low currents * The evolution of spoken language evolved for singing and emotional mate attraction first, then was used for abstract communication; so, it can be easier to do things with singing as opposed to speaking * Remedies for stutter: behavioral therapy, learning to speak slower, tapping out a rhythm – basically, sensory-motor integration tools – controlling what you hear with output * Going from thought to language to motor action (e.g., writing) takes four brain pathways working in coordination * Speech and movement pathways are adjacent – dancing/exercising/jogging/moving can help you think and stay cognitively intact

Read the full notes @ podcastnotes.org

My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis’ research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

InsideTracker: https://insidetracker.com/huberman

ROKA: https://roka.com/huberman

LMNT: https://drinklmnt.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Erich Jarvis & Vocal Communication

(00:03:43) Momentous Supplements

(00:04:36) InsideTracker, ROKA, LMNT

(00:08:01) Speech vs. Language, Is There a Difference?

(00:10:55) Animal Communication, Hand Gestures & Language

(00:15:25) Vocalization & Innate Language, Evolution of Modern Language

(00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders

(00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization

(00:31:34) Genes for Speech & Language

(00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes

(00:41:39) AG1 (Athletic Greens)

(00:42:52) Semantic vs. Effective Communication, Emotion, Singing

(00:47:32) Singing, Link Between Dancing & Vocal Learning

(00:52:55) Motor Theory of Vocal Learning, Dance

(00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions

(01:04:11) Facial Expressions & Language, Innate Expressions

(01:09:35) Reading & Writing

(01:15:13) Writing by Hand vs. Typing, Thoughts & Writing

(01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations

(01:26:58) Modern Language Evolution: Texting, Social Media & the Future

(01:36:26) Movement: The Link to Cognitive Growth

(01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation

(01:48:24) Evolution of Skin & Fur Color

(01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips

Title Card Photo Credit: Mike Blabac

Disclaimer

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My First Million

Podcast Notes Key Takeaways * MrBeast wants to “win” in business more than he wants to “make money” in business + He only wants to make money so that he can reinvest and grow his business * “I just want to make the greatest YouTube videos possible. That’s literally all I want.” – MrBeast * MrBeast on how he likes to work: “Wake up, obsess over something, go to bed. Wake up, obsess, go to bed. Like every second of the day until I have a mental breakdown and burn out and then I take a day off or maybe a day and a half and then go right back to it.” * “I like to find people who are the best in the goddamn world at their job and then empower them and give them money.” – MrBeast * Constantly consume a diverse set of information to spark creativity + MrBeast pays three people to discover obscure things and then teach him about those topics * Prior to his success, MrBeast’s obsession with YouTube was perceived as a negative quality, but now his obsession is celebrated * MrBeast spends about $1.5 million to create each video

Read the full notes @ podcastnotes.org

Episode 352: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) sit down with YouTube sensation MrBeast, and award-winning comedian Hasan Minhaj to talk about obsession, how to win, finding your creativity, measuring success, how to run a company... and more.

Links:

MrBeast
Hasan Minhaj
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(02:45) - What Hassan and MrBeast think of each other

(03:25) - How do you measure success?

(12:15) - How do you run your company?

(19:20) - Doing good while getting attention

(22:25) - Fitting in vs standing out

(25:55) - What are you trying to figure out?

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Starting Greatness with Mike Maples

Mike Maples, Jr of FLOODGATE welcomes back go-to-market expert and Stanford Graduate School of Business lecturer Mark Leslie for the second of their two-part interview, this time focusing on the role and responsibilities of a CEO and a deep dive into Leslie’s Compass, an essential set of heuristics for every startup founder. Leslie also discusses the value of founders focusing on a five-year plan for their startup, why it’s challenging to make meaningful change inside a large company, and why every founder should understand the relationship between their sales and marketing departments.

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The Fantastic History Of Food

Podcast Notes Intro * Julia Child was an American cooking teacher, author, television personality, and apparently, a WW2 spy that invented shark repellent cake—follow along as Nick Charlie Key tells the strange but true story * Host: Nick Charlie Key (@nickcharliekey)

Read the full notes @ podcastnotes.org

Even the most famous and lauded among us still have a few tasty secrets up their sleeves, and today we’re going to dive into this fascinating side of one of modern cookings most famous gourmands: Julia Child.

Thank you to Athletic Greens for being a sponsor for this episode.

To make it easy, Athletic Greens will give you a FREE 1 year supply of immune-supporting Vitamin D AND 5 FREE travel packs with your first purchase. All you have to do is visit www.athleticgreens.com/EMERGING to take ownership of your health and pick up the ultimate daily nutritional insurance!

Please support me on Patreon: https://www.patreon.com/foodhistorypod

Find transcripts and sources on the website: www.foodhistorypodcast.com

References:

https://allthatsinteresting.com/julia-child-spy
https://www.cia.gov/stories/story/julia-child-and-the-oss-recipe-for-shark-repellent/
https://www.cia.gov/stories/story/julia-child-cooking-up-spy-ops-for-oss/
https://www.washingtonpost.com/history/2022/05/02/julia-child-hbo-oss-sharks/
https://www.history.com/news/julia-child-oss-spy-wwii-shark-repellent

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Modern Wisdom

Podcast Notes Takeaways * Globalization is ending; the year 2019 is as good as it is ever going to be * After 70 years of people having fewer kids as a result of moving off the farm and into the city, the world is running out of mature adults, who are necessary for the consumption-based economic system to function * From an economic perspective, the U.S. is better positioned than most nations because its post-war generation actually continued to have kids at the onset of globalization + America has a much higher mortality rate once people age past 55 + American wealth gets cycled back to the younger generation much faster than in nations where people live to be much older

Read the full notes @ podcastnotes.org

Peter Zeihan is a geopolitical analyst, author and a speaker.

The world is changing faster than ever, and a lot of the countries, dynamics, peace treaties and structures we're familiar with may be about to come to an end. Peter's job consists of him analysing data from geography, demographics, and global politics to understand economic trends and make predictions. And if his predictions are correct, the next 50 years are going to look incredibly different.

Expect to learn why China will lose half of it's population by 2050, why globalisation is coming to an end even though we're more connected than ever, why population demographics are one of the most important factors in determining the future, whether automation will help or hinder us, whether food shortages are actually something to panic about and much more...

Sponsors:

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Extra Stuff:

Buy The End Of The World Is Just The Beginning - https://amzn.to/3AekTQz

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

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Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Huberman Lab

Podcast Notes Key Takeaways * Chronic alcohol intake, even at low to moderate levels (1-2 drinks per day or 7-14 per week), can disrupt the brain * When people drink, the prefrontal cortex and top-down inhibition are diminished and impulsive behavior increases – this is true in the short term while drinking, and rewires circuitry outside of drinking events in chronic drinkers (even those who drink 1-2 nights per week, long term) * Damaging effects to the prefrontal cortex and rewiring of neural circuitry are reversible with 2-6 months of abstinence for most social/casual drinkers; chronic users will partially recover but likely feel long-lasting effects * When people drink there is a shutdown of the prefrontal cortex and circuits that control memory, then there’s a fork in the road: group 1 – people who feel sedated after a few drinks; group 2 – people who do not feel sedated after a few drinks (predisposition to alcoholism) * People who start drinking at a younger age (13-15) are more likely to develop dependence, regardless of the history of alcoholism in their family; people who delay drinking to early 20s are less likely to develop dependence even if there’s a family history * People who drink consistently (even in small amounts i.e., 1 per night) experience increases in cortisol release from adrenal glands when not drinking so feel more stress and more anxiety when not drinking * With increased alcohol tolerance, you get less and less of the feel good blip and more and more of the pain signaling (so behaviorally you drink more to try to activate those dopamine and serotonin molecules again) * The risk of breast cancer increases among women who drink – for every 10 grams of alcohol consumed per day, there’s a 4-13% increase in the risk of cancer (alcohol increases tumor growth & suppresses molecules that inhibit tumor growth) * Regular consumption of alcohol increases estrogen levels of males and females through aromatization

Read the full notes @ podcastnotes.org

In this episode, I discuss the physiological effects that drinking alcohol has on the brain and body at different levels of consumption and over time. I also describe genetic differences that predispose certain individuals to alcoholism, binge and habit-drinking. I explain alcohol metabolism in simple terms and how it effectively acts as a poison, leading to cellular stress and damage. I then explain that it impacts neuronal function and changes our thinking and behavior – hallmarks of inebriation. I also discuss how alcohol consumption of different amounts impacts inflammation, stress, neurodegeneration, and cancer risk and negatively impacts the gut microbiome, brain thickness, hormone balance, mood and feelings of motivation. Additionally, I discuss the biology of hangovers and describe science-based strategies to mitigate the severity of a hangover. Since alcohol is one of the most widely consumed recreational substances, this episode ought to be of relevance to everyone. Indeed, even low-to-moderate alcohol consumption negatively impacts the brain and body in direct ways. The goal of this episode is to help people make informed decisions about their alcohol consumption that are in keeping with their mental and physical health goals.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Levels: https://levels.link/huberman

Eight Sleep: https://www.eightsleep.com/huberman

ROKA: https://www.roka.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Effects of Alcohol Consumption

(00:02:25) Momentous Supplements

(00:03:19) Low to Moderate Alcohol Consumption & Neurodegeneration

(00:06:52) Levels, Eight Sleep, ROKA

(00:10:46) Historical Context & Uses of Alcohol

(00:13:28) Alcohol Metabolism, “Empty Calories”

(00:18:23) Inebriation: Top-Down Inhibition, Impulsivity & Memory Formation

(00:24:23) Long-Lasting Effects & Impulsivity, Neuroplasticity & Reversibility

(00:27:55) Food & Alcohol Absorption

(00:30:07) Alcohol & Serotonin, SSRIs & Depression, Risk for Alcoholism, Blackouts

(00:37:39) Predisposition for Alcoholism; Chronic Consumption, Cortisol & Stress

(00:44:53) AG1 (Athletic Greens)

(00:46:07) Genetic Predisposition for Alcoholism, Consuming Alcohol Too Young

(00:52:27) Gut-Liver-Brain Axis: Alcohol, Gut Microbiome, Inflammation & Leaky Gut

(00:59:46) Tool: Improving/Replenishing Gut Microbiome

(01:02:44) Reducing Alcohol Consumption & Stress

(01:04:25) Hangover: Alcohol & Sleep, Anxiety, Headache

(01:12:11) Hangover Recovery, Adrenaline & Deliberate Cold Exposure

(01:17:16) Hangover Recovery, Dehydration & Electrolytes

(01:20:45) Types of Alcohol & Hangover Severity, Congeners

(01:25:25) Alcohol Tolerance, Dopamine & Serotonin, Pleasure-Pain Balance

(01:33:36) Are There Any Positive Effects of Alcohol?, Resveratrol

(01:35:42) Alcohol & Brain Thickness

(01:37:11) Alcohol & Cancer Risk: DNA Methylation, Breast Cancer Risk

(01:44:31) Mitigating Cancer Risk, Folate, B Vitamins

(01:46:54) Alcohol & Pregnancy, Fetal Alcohol Syndrome

(01:50:58) Hormones: Testosterone & Estrogen Balance

(01:55:09) Negative Effects of Alcohol Consumption

(01:58:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips

Title Card Photo Credit: Mike Blabac

Disclaimer

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Invest Like the Best

Podcast Notes Key Takeaways * Improvements in the highly regulated American Dynamism sectors like defense, housing, education, and healthcare will come from technological improvements, not policy improvements + These are the most regulated, most subsidized, and lowest-competition sectors * American Dynamism is an initiative to repair and strengthen the relationship between Silicon Valley and Washington to solve issues facing all Americans * Washington has a zero-sum culture that operates on short time horizons, while Silicon Valley has a positive-sum culture that operates on long time horizons * Authoritarianism gives Russia and China certain advantages over the U.S. because they can order their best technologists to build what the country needs, whereas the best technologists in the U.S. are left free to create better ad-optimizing tech for Snapchat * American Dynamism founders must be great storytellers;the technology is important, but the founder must be able to convince investors, customers, employees, and potential future employees that they are a paradigm-shifting company * The government must turn to other sources than its defense-industrial base to solve its shortcomings in software, the Department of Defense’s realization of this has marked a paradigm shift in Washington * The playbook for defense tech startups: Start competing for the smaller pockets of money that don’t touch the five defense primes (that receive 40% of the defense budget), and then move up the categories of spend and compete for contracts in areas that have been around for awhile * People opting out of a system oftentimes improves the underlying system * COVID forced parents to adopt a new model of educating their children, and like remote work, many parents were pleasantly surprised by the efficacy of the home-schooling and micro-schooling method * If all you need for work is an internet connection, people will move to states that are more aligned with their values and preferred policies, thus placing positive pressure on states to improve * Prices in regulated, subsidized, low-competition industries like defense, healthcare, and education don’t come down because they don’t need to come down * Investors must be mission-aligned with the company or they shouldn’t be working with them

Read the full notes @ podcastnotes.org

My guest today is Katherine Boyle, a general partner at Andreessen Horowitz. Katherine started her career as a reporter for The Washington Post before moving into VC at General Catalyst. She now leads a practice at a16z called American Dynamism, investing in companies that are solving critical issues in areas like defense, housing, and education. In the past year, I've spoken to Marc Andreessen, Josh Wolfe, and a number of founders about this need to build societally important businesses so I was excited to explore the topic in even more detail today. Please enjoy my conversation with Katherine Boyle.

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

The content here is for informational purposes only and should not be taken as legal, business, tax or investment advice, or be used to evaluate any investment or security and is not directed at any investors or potential investors in any a16z fund. For more details, please see a16z.com/disclosures.

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Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.

Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.

Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.

Follow us on Twitter: @patrick_oshag | @JoinColossus

Show Notes

[00:02:42] - [First question] - The origin and overview of the term American Dynamism

[00:05:01] - Why the shift to a move slow and make sure nothing breaks mentality

[00:07:31] - What about the American system today feels broken and stale

[00:09:48] - Becoming a journalist at The Washington Post

[00:11:35] - Describing the power landscape of media as it exists today

[00:12:28] - Major categories of American Dynamism that matter most

[00:14:29] - What matters more or less to her as an investor in these categories

[00:17:31] - Whether or not there’s anything fundamentally broken about our government

[00:19:36] - The Systems Bible; What excites her about aerospace and defense and what creates opportunity and demand in these sectors

[00:22:44] - Explanation of what it means when the factory is the product

[00:23:47] - How much is flowing into aerospace and defense currently

[00:26:01] - An overview of how lobbying works and who does it and why

[00:29:07] - Whether or not she considers these sectors from a bottom up perspective as in investor

[00:30:32] - What other categories she feels pulled towards

[00:33:09] - The biggest problems that currently exist in the K-12 school system

[00:35:34] - Thoughts on how states are competing citizens and how it plays into American Dynamism

[00:37:34] - The role immigration will play in range of outcomes in these main categories

[00:39:32] - Key takeaways about housing in light of American Dynamism

[00:42:09] - Her interpretation of the chart that shows inflation in categories over time

[00:44:40] - How different the investing dynamics are in all of these categories and thoughts on valuation in this world

[00:47:56] - Whether or not expected returns and risk profiles are different in this area

[00:48:36] - The importance of effective a founder’s storytelling, knowledge and customer empathy

[00:49:55] - Overview of the anatomy of a great story

[00:51:30] - The story she tells founders at this stage so establish a partnership

[00:52:46] - The kindest thing that anyone has ever done for her

The Systems Bible: The Beginner's Guide to Systems Large and Small

View Details

Huberman Lab

Podcast Notes * Daily morning sunlight & sunset viewing * Tip: in the winter months, get 30 minutes of sunlight viewing while you have it * Daily non-sleep deep rest (such as yoga Nidra which puts you into a state of feeling, not planning) 10-30 minutes, usually in the afternoon or in the morning on days after poor sleep * Wake up groggy but sleeping plenty? Consider setting the alarm at the end of your ultradian cycle so you may get less sleep, but it will coincide better with natural rhythms

Read the full notes @ podcastnotes.org

Recently I had the pleasure of hosting two live events, one in Seattle, WA and one in Portland, OR. These events were part of a lecture series called The Brain Body Contract. My favorite part of each evening was the question & answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event in Seattle, WA.

Attend The Brain Body Contract Live Events

Los Angeles, CA: October 16, 2022

New York, NY: November 9, 2022

https://hubermanlab.com/tour

Presale password: huberman

Thank you to our sponsors

Momentous: https://www.livemomentous.com/huberman

InsideTracker: https://insidetracker.com/huberman

Timestamps

(00:00:00) The Brain Body Contract Q&A

(00:01:07) Momentous Supplements, InsideTracker

(00:01:35) Upcoming Live Events: Los Angeles & New York

(00:02:16) What Is Your Most-Used Protocol?

(00:04:12) Should You Vary Wake-Up Time Seasonally?

(00:06:05) Why Is My Drive Depleted Upon Waking-Up?

(00:08:42) What Are Your Favorite/Most Impactful Books?

(00:12:08) What Excites You About the Future of Mental Health Treatment?

(00:17:25) What Is the Biggest Area Tor Performance Enhancement?

(00:21:44) Can You Still Do a Kickflip?

(00:22:32) Tips on How to Improve Memory

(00:24:54) How Do You Manage Social Media Addiction?

(00:27:43) Were You Nervous Tonight/ How Did You Prepare?

(00:29:10) Is Learning from Failure Equal to Learning from Success?

(00:32:23) When Are You Going to Start Training Jiu-Jitsu?

(00:33:28) Discuss the Supplements You Take

(00:36:29) Advice or Protocols to Improve Learning & Retention

(00:38:42) What Exciting Research/Work are You Doing?

(00:40:22) How Does Dopamine Factor into Neuroplasticity?

(00:43:12) What Advice Do You Have for Future Scientists?

(00:46:47) Is Age 66 Too Old for Neuroplasticity & Learning?

(00:48:00) How Do You Read Research Papers?

(00:49:40) What is Your Favorite Condiment?

(00:50:10) Most Important Takeaway from Your ADHD Research?

(00:52:58) What Future Episodes Are in the Pipeline?

Title Card Photo Credit: Mike Blabac

Disclaimer

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Twenty Minute VC

Podcast Notes Intro * Sheel Mohnot (@pitdesi) is a Co-Founder and General Partner at Better Tomorrow Ventures, a $225M venture fund for pre-seed and seed-stage fintech companies around the globe * Even if you’re not a multi-million dollar angel investor like Sheel, his lessons are applicable to the everyday person trying to invest in good companies * Host: Harry Stebbings (@HarryStebbings)

Read the full notes @ podcastnotes.org

Sheel Mohnot is a Co-Founder and General Partner @ Better Tomorrow Ventures, a $225M fund that leads rounds in pre-seed and seed-stage fintech companies globally. Sheel and Jake (his co-founder) invested for many years together before founding BTV and wrote checks into Mercury, Flexport, Ramp, and Hippo Insurance to name a few. As for Sheel, before BTV he ran 500 Fintech for close to 7 years, and before that was a founder, founding two companies, both of which were acquired. If that was not enough, Sheel is also a master at measuring the width of swimming pools and making cameo appearances in music videos with Justin Bieber.

In Todays Episode with Sheel Mohnot We Discuss: 1.) Entry into Venture:

How Sheel made his way into the world of venture having founded 2 fintech companies?
Why did no LPs give Sheel money in the early 500 Fintech days? What were some of his biggest lessons from investing in 100s of companies with 500 Fintech?
How did BTV with Jake come together most recently? What are the biggest differences to Sheel of being a fund manager vs being an investor?

2.) The Power Law:

How does Sheel define "the power law" in venture capital? What multiple of return would be power law status?
Given the size of outcome available with these power law returns, how does Sheel approach portfolio construction? Would it not be best to invest in 100s of companies?
Who does Sheel believe has done the indexing approach best? Why?

3.) Venture Capital has Never Been Less Collaborative:

Why does Sheel disagree with Harry that venture capital has never been less collaborative?
Why now, for the first time, are large multi-stage funds taking single-digit ownership?
Does Sheel agree with Harry it is moronic to have "guaranteed pro-rata"? How does Sheel approach re-investment decision-making? When does he pay up vs not?

4.) The Biggest Wins and Misses:

What have been Sheel's biggest wins from a cashback and a multiple perspective?
How did Sheel miss the chance to invest in both Robinhood and Chime early on? What did he not see? How would he have thought differently with the benefit of hindsight?
How have Sheel's biggest hits and misses impacted how he invests today?

5.) Emerging and Frontier Markets:

Does Sheel share Harry's concern for the removal of capital from emerging markets?
Why does Sheel believe that India, South East Asia and LATAM will be fine?
Why does Sheel believe Pakistan and Africa are most in trouble?
What advice does Sheel give to his emerging markets founders today?

Items Mentioned in Today's Episode: Sheel's Favourite Book: Enders Game

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Huberman Lab

Podcast Notes * Only by clearly defining what you want in your last decade of life can you work backwards and put in place a plan to get there * Two vectors of longevity: (1) lifespan: literally whether you are alive and breathing; (2) healthspan: how many healthy years you live – biomarkers matter less, physical & performance tests matter more (DEXA scan, VO2, fat oxidation, emotional state, etc.) * ApoB is the single most important biomarker to measure – be proactive in obtaining this as early as possible! It’s uncommon in the U.S. though used in Europe & other places as part of regular health check * You should monitor weight but an annual DEXA scan is more valuable than tracking BMI * “There’s not one thing I’ll tell patients that is more important than exercising.” – Peter Attia * “Strength training is an essential part of our existence. It’s never to late to start but you should never stop.” – Peter Attia * Try the back casting thought experiment: In detail, what do you want the last 10 years of life to look like? Then you can plan and live accordingly. Until you do, everything is abstract. * Peter Attia on the Women’s Health Initiative that deterred the medical community from hormone replacement therapy for women: “It’s hands down the biggest screw up of the entire medical field in the last 25 years.” – Peter Attia * Philosophical differences in prevention – Medicine 2.0: we’ll treat you if it seems like disease is imminent in the next 5-10 years; Medicine 3.0: treat the causative agent now

Read the full notes @ podcastnotes.org

My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

Helix Sleep: https://helixsleep.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Assessing Health Status & Improving Vitality

(00:02:51) Momentous Supplements

(00:03:46) Thesis, InsideTracker, Helix Sleep

(00:07:29) Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease”

(00:11:51) Healthspan: Functional Testing, Cognitive & Emotional States

(00:13:59) Blood Testing: Best Frequency

(00:16:01) DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis

(00:22:33) Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids

(00:29:24) Osteopenia & Osteoporosis Diagnosis, Strength Training

(00:31:03) AG1 (Athletic Greens)

(00:32:16) Back-casting: Defining Your “Marginal Decade”

(00:38:31) All-Cause Mortality: Smoking, Strength, VO2 max

(00:44:43) Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals

(00:49:24) Importance of Exercise, Brain Health, MET hours

(00:55:23) Nicotine & Cognitive Focus

(01:03:12) Menstruation, PMS & Menopause

(01:10:10) Hormone Replacement Therapy, Menopause & Breast Cancer Risk

(01:22:06) Estrogen, Progesterone & Testosterone Therapies in Women

(01:26:35) Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin

(01:37:23) Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG

(01:47:46) Fadogia Agrestis, Supplements, Rapamycin

(01:52:06) Testosterone Replacement Therapy & Fertility

(01:59:26) Total Testosterone vs. Free Testosterone

(02:02:51) Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B

(02:17:42) Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions

(02:25:15) Cardiovascular Disease, Age & Disease Risk

(02:28:53) Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation

(02:37:40) Metabolomics & Exercise

(02:40:44) GLP-1 & Weight Loss

(02:47:06) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips

Title Card Photo Credit: Mike Blabac

Disclaimer

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Huberman Lab

Podcast Notes Key Takeaways * High-quality sleep is critical! Sleep is the foundation of mental health, cognitive health, and performance * Viewing direct morning sunlight within 30-60 minutes of waking will help you fall asleep and stay asleep at night, and optimize cortisol & adenosine levels * Layer in multiple levers to be more alert: morning sunlight viewing, increasing body temperature, delaying caffeine, movement/exercise upon waking, light breakfast * Stack the deck to give your body predictable autonomic timing and properly set circadian rhythm to optimize sleep and wakefulness – even if you’re tired, exercise a little (doesn’t have to be intense) and eat a light breakfast, etc. * Avoid overhead fluorescent light as much as possible between 10pm-4am – these lights will eliminate melatonin circulating in brain & body and will hinder ability to fall and stay asleep (instead, try soft lamps and dim screens as much as possible without straining eyes) * Viewing afternoon sunlight from sunset can help offset some of the negative effects of light viewing in the evening (10 pm-4 am) * Try to maintain a consistent sleep/wake schedule (+/- 1 hour) 7 days a week! * When all else fails, try this sleep stack cocktail (buy single ingredient supplements so you can use what works, ditch what doesn’t): magnesium threonate (145mg, 30-60 minutes before bed) + theanine (100-400mg, 30-60 minutes before bed) + apigenin (50mg, 30-60 minutes before bed) * Sleep apnea can have very damaging effects on sleep and health – train nasal breathing with these methods: (1) use medical tape to tape mouth shut during sleep; (2) practice nasal breathing only during light exercise/cardio bouts

Read the full notes @ podcastnotes.org

In this episode, I describe a comprehensive toolkit consisting of behavioral and supplement-based tools that you can customize to enhance the quality, duration and impact of your sleep. This has an enormous positive impact on your overall health and daytime functioning, brain, hormones and immune system. I teach you how to effectively harness light (and darkness), temperature, food, exercise, caffeine, supplements, and digital devices in order to fall asleep faster, stay deeply asleep longer and overall, and achieve better quality sleep. I also describe how these tools can be modified to recover quickly from a poor night’s sleep, jet lag or bouts of shift work. Given that sleep is the foundation of all mental health, physical health and performance, this episode should benefit everyone as it provides an essential toolkit of science-supported, low- to zero-cost strategies that can be tailored to optimize your sleep routine.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

InsideTracker: https://insidetracker.com/huberman

Eight Sleep: https://www.eightsleep.com/huberman

LMNT: https://drinklmnt.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman

For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Tools to Optimize Sleep

(00:03:02) Momentous Supplements

(00:04:16) InsideTracker, Eight Sleep, LMNT

(00:08:24) Factors to Control Circadian Rhythm & Sleep

(00:15:10) Morning Tool: Morning Sunlight Viewing, Cortisol

(00:20:44) Morning Sunlight: Circadian Rhythm, Artificial Lights, Cloudy Days

(00:26:18) Evaluating Light in Environment, Compensating for Missed Morning Light

(00:29:26) AG1 (Athletic Greens)

(00:30:46) Morning Tools: Temperature & Deliberate Cold Exposure, Exercise

(00:34:58) Timing Caffeine, “Afternoon Crash,” Exercise

(00:40:08) Timing Eating, Alertness & Circadian Rhythm

(00:45:20) 3 Daily Critical Periods

(00:46:49) Afternoons: Naps, Deep Relaxation (NSDR, Self-Hypnosis), Exercise & Body Temperature, Caffeine

(00:51:59) Afternoon Tools: Viewing Sunlight in Late Afternoon, Evening Light

(00:56:45) Evening/Night Tools: Overhead Artificial Lights, Light Sensitivity

(01:04:40) Evening Tools: Hot Bath/Sauna, Temperature & Sleeping Environment

(01:09:40) Alcohol, THC & Reduced Sleep Quality; CBD, Anxiety & Falling Asleep

(01:11:45) Sleep Supplements: Magnesium Threonate, Apigenin & Theanine

(01:16:34) Melatonin Supplementation (Caution)

(01:17:44) Additional Sleep Supplements: GABA, Glycine, Myo-Inositol & Anxiety

(01:20:08) Falling Back Asleep: Reveri App, NSDR, Yoga Nidra

(01:22:55) Staying Asleep: Eye Masks, Ear Plugs, Elevating Feet

(01:24:58) Tool: Sleep Apnea & Nasal Breathing

(01:28:20) Sleep Schedule Consistency, Weekends, Compensatory Sleep & Caffeine

(01:31:14) Tools: Temperature Minimum & Jet Lag, Shift Work & Red Lights

(01:37:38) Behavioral Tools for 3 Daily Critical Periods

(01:39:26) Zero-Cost Support, YouTube Feedback, Huberman Lab Clips, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Genius Life

Podcast Notes Key Takeaways * Alzheimer’s Disease is a deadly neurological condition that affects +5 million people in the United States alone, and there are no meaningful treatments currently on the market * About 60% of the calories that the average American consumes comes from ultra-processed food products; there are very powerful forces working to mislead the public on food and health education * Ultra-processed foods are associated with early mortality and increased risk for dementia, and yet the popular Food Pyramid recommends 7-11 servings of grain per day, which tends to be ultra-processed and refined * A 2022 meta-analysis revealed that there is no evidence to suggest that depression is caused by a chemical imbalance in the brain * People have been led to falsely believe that there is a 1:1 cause and effect relationship between having a chemical imbalance and depression * “People tend to want an easy fix; they want a magic pill. They want change, but they don’t want to change.” – Matt Bilinsky * Lifestyle modification in the areas of diet and exercise have shown to be powerful antidepressants, but making changes in these two areas is more difficult than taking a pill from the medicine cabinet * The Amyloid Hypothesis suggests that excessive amounts of plaque build-up in the brain causes Alzheimer’s; however, new studies indicate that plaque build-up is not causal * In 2022, an investigation revealed that all of the data from the 2006 amyloid-beta study was fraudulent, and found that Amyloid-beta is a symptom, but not the cause of Alzheimer’s * Not only is the establishment increasingly wrong, but its reaction to anyone that questions it poses another threat to society

Read the full notes @ podcastnotes.org

Max Lugavere is a science journalist, host of The Genius Life podcast, and New York Times best-selling author. His latest book, Genius Kitchen: Over 100 Easy and Delicious Recipes to Make Your Brain Sharp, Body Strong, and Taste Buds Happy, is out now.

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Starting Greatness with Mike Maples

During the 1990s, Mark co-founded Veritas Systems, which he piloted from nothing to 6,000 employees and $1.5B in revenue in a decade. Now a lecturer in management at the Stanford Graduate School of Business, Leslie is one of the foremost experts in go-to-market strategy in Silicon Valley, and in the first of this two-part series with Mike Maples, Jr of FLOODGATE, Leslie discusses what strategies he used to make Veritas a runaway success, and the origins for the Sales Learning Curve.

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Knowledge Project

Podcast Notes Key Takeaways * Insights are disorienting and they make you change the way you think; organizations think they want insights and innovation and say that they want innovation, but in reality, they don’t, because insights force them to change * Organizational mistakes are costly and public, but no one knows when an institution fails to make an insight, which is why they often default to error reduction * Innovations have a track record of failure until they ultimately succeed, so it’s easy to dismiss something that has failed 9 times, not knowing that a 10th iteration may have resulted in the innovation materializing * Experts are well-aware of their mistakes; their mistakes eat away at them * It’s our natural tendency to dismiss anomalies because they threaten our existing worldview, but we should explore them when they happen * People tend to reach a certain level of performance, and then they stagnate; the ones that continue improving engage in a process of “unlearning” where they question their previously held notions about the given subject and explore new depths that would have otherwise remained unexplored had they not questioned their mental model * Experts welcome the chance to operate outside their comfort zone of routines because it may result in new insights, whereas journeymen are reluctant to operate in the gray area because their tried-and-true techniques and routines aren’t useful * Making mistakes + reflecting on those mistakes = progress toward becoming an expert * Biases are related to our experiences; we don’t dismiss our experiences, why should we dismiss our biases? * “If the advantages and the disadvantages of the two options are almost perfectly balanced, it doesn’t matter which one we pick.” – Gary Klein on the Zone of Indifference + And yet people and committees will spend an enormous amount of time mulling over the choice when in reality it won’t materially matter which one they choose * Instead of gaining compliance through fear and intimidation, work to gain compliance through trust and faith

Read the full notes @ podcastnotes.org

Celebrated research psychologist Gary Klein has spent nearly 50 years studying how and why people make the decisions they do. On this episode, Klein calls on those five decades of experience to discuss pioneering the field of naturalistic decision making, the difference between experience and expertise, why some people stagnate at an intermediate level, Cognitive Flexibility Theory, the role of storytelling, how to gain insights, fixation errors, cognitive biases, mental models, how to fast-track expertise, and so much more. During his career Klein has developed several models of cognitive processes as well as research and application methods, some of which have been incorporated in U.S. Army doctrine for command and control. In 2015 Klein founded ShadowBox LLC, a cognitive skills training company that has been employed in the military, law enforcement, healthcare, social services, and petrochemical domains, and provides a flexible, scenario-based training technique that allows trainees to see the world through the eyes of experts. He is also the author of five books, including the 2013 release Seeing What Others Don't: The Remarkable Ways We Gain Insights. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Pomp Podcast

Podcast Notes Key Takeaways * The average person in America is not woke; reducing people down to their race and gender is regressive, and seems to be the exact opposite of what society has worked to improve over the last several decades * Mike believes the urgency to indoctrinate the next generation with wokeness is why college is forced so heavily on younger generations * People tend to navigate toward the extreme, the bizarre, the controversial on social media because that’s what is rewarded + Mediocracy has the same voice; having a unique voice is the only thing that matters now * The chaos of the world reveals itself when the people in charge are proven wrong; the Tom Cruises of the world have become completely normalized, and that is good for culture * The world of blindly following the narratives of the hegemonic media empires is over * In the modern information war, you are either an internet detective or you are clueless about what is going on * The tech industry is powerful and worth critiquing, but it’s more productive to critique abuses of power than the concepts of business and capitalism in general * America’s biggest problem is that it is so easy to succeed here; we have a lot of room to fail, and we’re still thriving.” – Mike Solana * The truth matters, but storytelling is of similar (or more) importance in the modern information war * In the long-term, it’s improbable for America to enter the dark ages; the more interesting question is whether or not America becomes great, and “culture” will be the deciding factor * You can begin to solve the problems of the world by starting with your home; make where you are physically living a better place

Read the full notes @ podcastnotes.org

Mike Solana is a Vice President of Founders Fund, the ring leader of Hereticon, and Editor-In-Chief At Pirate Wires.

In this conversation, we talk about everything: politics as theater, if the truth exists anymore, why science is no longer science, the changing definitions in society, AOC, Ron DeSantis, Donald Trump, Joe Biden, Gavin Newsom, conspiracy theories such as lab leak & Hunter Biden, and more! Nothing is off limits in this conversation.

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Crypto wallets and browser extensions are outdated, limited in features, and don’t meet the needs of today’s Web3 users. Core, the free, non-custodial browser extension built by Ava Labs, is more than just a wallet. Core is packed with features that give Avalanche users a more seamless, and secure, Web3 experience.

With Core, any crypto user can easily swap assets, display NFTs in a beautiful interface, and store your assets in a Ledger-enabled wallet. Plus you can put real dollars in your Core wallet in just a few clicks.

Go to www.core.app to access the full power of Web3 on Avalanche!

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Either sign up for a free blockchain.wallet or visit Unstoppabledomains.com to buy your domain today.

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Bullish is a powerful new exchange for digital assets that offers deep liquidity, automated market making, and industry-leading security. Combining the innovations of DeFi with the regulated environment of traditional finance, Bullish empowers users to trade with certainty and earn passively at scale across variable market conditions, in an environment backed by multibillion-dollar liquidity contributions from the Bullish Treasury. Visit bullish.com/pomp today to learn more.

Note: Bullish is licensed by the Gibraltar Financial Services Commission. Virtual assets and related products are high risk. Consult your investment advisor and trade responsibly. Bullish is available in select locations only and not to U.S persons. Visit bullish.com/legal for important information and risk warnings.

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Download the FTX App today and use referral code “Pomp” to earn free crypto on every trade over $10. The more you trade, the more you earn.

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Valour (formerly DeFi Technologies) represents what’s next in the digital economy -- providing simplified, trusted access to crypto, decentralized finance and Web 3.0 investment opportunities. Institutions and investors can gain diversified, secure, compliant, and easily tradable access to a diversified set of industry-leading equity products and protocols, through a single stock purchase on a regulated exchange. Currently listed on U.S. (OTC: DEFTF) and Canadian (NEO:DEFI) exchanges.

For more information or to subscribe to receive company updates and financial information, visit our website at valour.com

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BCB Group is the leading payment services partner for the digital assets industry. BCB Group provides payment services in 30+ currencies, FX, cryptocurrency liquidity, digital asset custody and BLINC, which is BCB’s free, instant settlements network for the BCB client ecosystem.

Find out more by visiting bcbgroup.com/pomp

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View Details

Chase Jarvis Live Show

Podcast Notes Key Takeaways * Check out The Chase Jarvis LIVE Show Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Steven Pressfield is a bestselling author of a number of both fiction and nonfiction books, such as The Legend of Bagger Vance and Tides of War. He also has bestselling classics on creativity, such as the War of Art and Turning Pro.

I have read and recommended many of Steven’s books to my audience and fellow creatives over the years and am indebted to him, particularly for his work in The War of Art. Our recent conversation on my show focused on his most recent book, Put Your Ass Where Your Heart Wants to Be, as well as a sneak preview into another book that will be released later this year!

Enjoy!

Highlights from the Show:

[00:00] Intro

[02:03] The War of Art

[03:30] Big “R” Resistance

[07:25] Turning Pro

[09:43] Put Your Ass Where Your Heart Wants to Be

[17:46] The Cost of Not Pursuing Your Dreams

[19:01] Talent is Bullshit

[27:00] You want to do good work? Show me all your garbage

[32:22] Creative Process of Steven Pressfield

[42:58] The Risking Thing is Where the Best Stuff Lies

[56:50] The Hero’s Journey

Today's episode is brought to you by CreativeLive. CreativeLive is the world's largest hub for online creative education in photo/video, art/design, music/audio, craft/maker and the ability to make a living in any of those disciplines. They are high quality, highly curated classes taught by the world’s top experts -- Pulitzer, Oscar, Grammy Award winners, New York Times best selling authors and the best entrepreneurs of our times.

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The Daily Stoic

Ryan talks to Morgan Housel about the real definition of wealth, the intricacies of building an audience as an author, the sacrifice required to gain success, and more.

Morgan Housel is a partner at The Collaborative Fund. His book The Psychology of Money: Timeless lessons on wealth, greed, and happiness is a deep dive into the psychology of money and investing. Morgan is a two-time winner of the Best in Business Award from the Society of American Business Editors, winner of the New York Times Sidney Award, and a two-time finalist for the Gerald Loeb Award for Distinguished Business and Financial Journalism. He serves on the board of Markel and has presented at more than 100 conferences all over the globe.

✉️ Want Stoic wisdom delivered to your inbox daily? Sign up for the FREE Daily Stoic email at https://dailystoic.com/dailyemail

🏛 Get Stoic inspired books, medallions, and prints to remember these lessons at the Daily Stoic Store: https://store.dailystoic.com/

📱 Follow us: Instagram, Twitter, YouTube, TikTok, and Facebook

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Psychology of Money: Timeless lessons on wealth, greed, and happiness

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The Reason Interview With Nick Gillespie ✓

Claim

Podcast Notes Intro * John Cleese (@JohnCleese) is an English actor, comedian, screenwriter, producer, author, and satirist of everything serious. He’s most famous for his lead role in Monty Python and other appearances in James Bond, Harry Potter, Shrek, and more! * John Cleese and Nick Gillespie discuss how wokeness is destroying the environment needed to foster creativity * Check out Cleese’s recent book:Creativity: A Short and Cheerful Guide – “You can teach people how to create circumstances in which they will become creative” * Host: Nick Gillespie (@nickgillespie)

Read the full notes @ podcastnotes.org

The Monty Python legend says political correctness poisons thinking in all areas of human activity.

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Artificial Intelligence Podcast

Podcast Notes Intro * “We want [Coinbase] to be the way that a billion people access the open global financial system.” – Brain Armstrong * All of Brian’s friends thought Coinbase was a dumb idea when he first started building it in 2010; there was a lot of uncertainty around Bitcoin at the time, which was trading at $10 per coin * Most of the best leaders are able to contribute a net positive to the world and do not care if they anger a certain percentage of people + You’ll never do something authentic to yourself if you care too much about what people think * Early startups need to “keep doing stuff” and aggressively iterate on their product or service + “Startups are like sharks; if they stop swimming they die.” – Paul Graham * People who are uncertain about their future don’t try as hard to make or achieve things because everything they produce and earn could be gone tomorrow; good property rights are foundational * Bitcoin is a new technology that can bring economic freedom to everyone around the globe, specifically in places where economic freedom had not previously existed * “I think Bitcoin could end up becoming the reserve currency of the world.” – Brain Armstrong * Companies are getting distracted from working on their core missions by “the current thing”, which is destructive to their productivity + It’s not Coinbase’s job to solve the most important societal issues + Focus on work at work and pursue your other interests during your own time * To become a better leader, consistently do things outside of your comfort zone so that your comfort zone grows * It is easy to be a critic; be the person in the arena that uses technology to improve the world and is a part of the solution and not a part of the problem

Read the full notes @ podcastnotes.org

Brian Armstrong is the CEO of Coinbase. Please support this podcast by checking out our sponsors: – Audible: https://audible.com/lex – Skiff: https://skiff.org/lex – BiOptimizers: http://www.magbreakthrough.com/lex to get 10% off – Fundrise: https://fundrise.com/lex – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil EPISODE LINKS: Brian’s Twitter: https://twitter.com/brian_armstrong Brian’s Instagram: https://www.instagram.com/brian_armstrong Coinbase’s Website: https://www.coinbase.com ResearchHub: https://www.researchhub.com NewLimit: https://www.newlimit.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support

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Pomp Podcast

Podcast Notes Intro * Andrew Tate (@cobratate) has lived countless different lives and is in the running for the most viral man on the internet. But are his hot takes as sizzling as the infamous Alex Jones? Find out here. * This conversation was recorded in May 2021, Pomp sat on it until Andrew Tate’s popularity blew up. These are his opinions on the world. * Host: Anthony ‘Pomp’ Pompliano (@APompliano)

Read the full notes @ podcastnotes.org

This episode is a conversation with Andrew Tate, the most viral person on the internet right now.

This conversation was recorded back in May of 2021. In this discussion, Andrew shares his unique and often controversial opinions about society. Some I agree with, some I do not. What's clear is that Andrew has mastered the internet and the social media algorithm, and I thought it would be important to share his opinions as part of the broader conversation in a free speech society.

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Huberman Lab

Podcast Notes Key Takeaways * How you visualize a goal or problem in your mind dictates how well you lean into that goal: whether you will be able to meet the goal, how you feel after, and your capacity to tackle larger goals * “Proximity to a goal increases the investment and resources that people use to meet that goal.” – Dr. Emily Balcetis * Set goals that are challenging but not impossible – and – not so easy that it’s a no-brainer or requires minimal effort * Overweight/deconditioned people see the world as more challenging: hills are steeper, finish lines are further – which shifts these people into a state of fatigue and makes it harder to start & overcome * Trouble finishing your run? Focus on intermediate targets along the way which makes the goal feel closer and you push harder * Visualization/vision boards alone are not enough! To put visualizations into action: (1) set a plan – break it down into practical day-to-day; (2) think about obstacles that stand in the way of success so they don’t surprise you along the way * When setting goals you can’t tangibly see, don’t count on your memory – write down progress along the way or use an app to help you more accurately track & reflect on progress

Read the full notes @ podcastnotes.org

My guest this episode is Dr. Emily Balcetis, PhD, Professor of Psychology at New York University (NYU). Dr. Balcetis’ research focuses on how our perception of the world, particularly our visual perceptions, influences our level and persistence of motivation, how we conceptualize goals, actual goal achievement, and our emotional state as we pursue goals. Dr. Balcetis explains how to best visualize and overcome challenges in pursuit of larger, complex goals. We also discuss the science of how to define goals and intermediate milestones, overcome obstacles, and effectively track progress. This episode highlights science-based, immediately actionable tools that anyone can use to set and achieve physical and/or cognitive goals more effectively.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

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Supplements from Momentous

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For the full show notes, visit hubermanlab.com

Timestamps

(00:00:00) Dr. Emily Balcetis, Visualization of Goals & Motivation

(00:03:24) Momentous Supplements

(00:04:38) Thesis, Levels, ROKA

(00:08:08) Vision & Motivation

(00:11:37) Tool: Narrowing Visual Focus & Improving Exercise

(00:21:39) Adjusting Visual Attention & Perceived Fatigue

(00:25:14) Tool: Visual Focus “Spotlight”

(00:27:57) Tool: Goal Gradient Hypothesis, Visual Spotlight to Increase Effort

(00:33:38) AG1 (Athletic Greens)

(00:35:00) Defining Goals vs. Accomplishing Goals, Dream Boards & Goal Lists

(00:41:28) Tool: How to Setting Better Goals & Identify Obstacles

(00:46:38) Vision is Unique, Challenging the Visual System, Realistic Goals & Micro-Goals

(00:57:12) Do Fit People View the World Differently?, States of Body & Visual Experiences

(01:05:54) Caffeine, Stimulants, Visual Windows & Motivation

(01:10:13) Tools: Goal Setting & Cognitive (Non-Physical) Goals, Data Collection

(01:21:54) Year in Review & Memory

(01:26:32) Visual Tools & Mental Health, Depression & Visual Priming

(01:31:33) Focusing Attention & Increasing Visual Detail/Resolution

(01:36:12) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Neural Network Newsletter, Instagram, Twitter, Momentous Supplements

Title Card Photo Credit: Mike Blabac

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Knowledge Project

Podcast Notes Key Takeaways * Mimetic desire: whatever the people you surround yourself with want, you end up wanting as well, i.e. being subconsciously driven to achieve external validation rather than intrinsic validation * The constant desire to want to improve parts of your life or business turns your weaknesses into strengths * “Most successful people are just an anxiety disorder harnessed for productivity” – Andrew Wilkinson * Andrew focuses on building businesses that do not compete with venture capital and whose success can be predicted with reasonable certainty * Andrew applies the “80/20 rule” to learning about health; spend an hour a month reading all of the scientific summaries and then don’t think about it again * On raising kids with wealth: “At the end of the day, your kids just need to know that you’re there and you love them, and I hope that’s enough.” – Andrew Wilkinson * The Concept of Self-Binding: create an environment where you can’t do the things you don’t want to do, such as eating ice cream, by removing the stimulus from your environment completely * The unconscious mind is far more powerful than the conscious mind

Read the full notes @ podcastnotes.org

Canadian businessman and billionaire investor Andrew Wilkinson has made a successful career out of channeling his entrepreneurial spirit, but he knows that sometimes that energy can be a double-edged sword. On this episode, Wilkinson goes in-depth on the lessons learned from a career that’s seen him build a business empire of more than 40 companies, but also why he’s had to re-calibrate his personal goals after struggling to find happiness in the summer of 2021. He also discusses mimetic desire, building a business in a small Canadian market, competing with venture-backed companies, strategies for hiring CEOs, the mistakes that have cost him millions of dollars, and so much more. Wilkinson is the co-founder of Tiny Capital, which boasts an enterprise value of more than $1 billion and owns 35 different companies including AeroPress, MetaLab and Dribble. He is also the co-founder and chairman of WeCommerce, a holding company that starts, buys, and invests in the world’s top Shopify businesses. He is based in Victoria, British Columbia. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Software Engineering Daily

<p>Originally published on July 11, 2016. Negotiation is an important skill for software engineers. The salary you negotiate at the beginning of your job could be a difference of tens of thousands of dollars over the course of an engineer’s career, but intimidating recruiters and exploding offers scare many engineers from negotiating at all. Today,</p>

<p>The post <a rel="nofollow" href="https://softwareengineeringdaily.com/2022/07/22/salary-negotiation-with-haseeb-qureshi-2/">Salary Negotiation with Haseeb Qureshi</a> appeared first on <a rel="nofollow" href="https://softwareengineeringdaily.com">Software Engineering Daily</a>.</p>

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Huberman Lab

Podcast Notes Key Takeaways * Manic episodes are the defining criteria of bipolar disorder AKA bipolar depression – not all people with bipolar disorder experience deep depression * Types of bipolar disorder: (1) Bipolar I – characterized by an extended period of mania (elevated mood, impulse, distractibility, etc.) – the mania is extreme and noticeable to people around; (2) Bipolar II – characterized by swings of hypomania (lessened intensity of mania or shorter duration of mania) and depressive episodes * Bipolar I presents itself more overtly because of bouts of mania; Bipolar II can duck under the radar because of the intense depressive state and hypomania which might look more normal compared to a depressive state * Heritability of bipolar disorder among the general population is 85% – if someone has bipolar disorder, it’s likely they inherited a gene, set of genes, or susceptibility in genes to influences that can trigger bipolar disorder * Major neurological deficits in people with bipolar disorder: (1) lack of internal awareness (interoception); (2) top-down control on overall levels of energy (reduction in connectivity between parietal region and limbic system) * Treatment approaches need to be comprehensive and in combination – for example, lithium + talk therapy * “It’s naïve and in fact, wrong, to say that lifestyle interventions alone are going to prevent especially extreme forms of mania and depression.” – Dr. Andrew Huberman

Read the full notes @ podcastnotes.org

In this episode, I explain the biology, symptoms, causes and types of bipolar disorder (sometimes called bipolar depression). I discuss neuroplasticity and how the brain normally regulates mood, energy, and perceptions; then, I contrast that with the biology of bipolar disorder, which is characterized by extremes of energy and mood, e.g., mania and depression. I outline the mechanisms through which bipolar disorder manifests in the brain, including deficits of interoception and reduced connections between the parietal and limbic systems. I also outline how treatment options (such as lithium) work in part through homeostatic plasticity.’ I discuss not only lithium but also the treatment of bipolar with ketamine, different talk therapies, electroconvulsive therapy, transcranial magnetic stimulation, and nutraceuticals, including Omega-3 and Inositol supplementation. This episode should interest anyone who has or knows someone with bipolar disorder and, more broadly, those interested in how the brain works to create a balance between thoughts, energy levels, focus, and mood.

Thank you to our sponsors

InsideTracker: https://insidetracker.com/huberman

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Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Bipolar Disorder

(00:02:23) Momentous Supplements

(00:03:42) Tool: Appetite Suppression & GLP-1, Parallel Pathways, Yerba Mate

(00:10:23) InsideTracker, ROKA, Blinkist

(00:14:24) Prevalence & Severity of Bipolar Disorder

(00:16:30) Bipolar Disorder I, Diagnostic Criteria of Mania

(00:28:58) Bipolar Disorder II, Individual Variability

(00:33:07) Bipolar I vs. Bipolar II: Manic, Depressive & Symptom-Free States

(00:38:20) Consequences of Bipolar Disorder, Heritability

(00:46:53) Bipolar Disorder vs. Borderline Personality Disorder

(00:51:51) Mania & Depression, Negative Impacts

(00:53:06) History of Lithium Treatment

(01:02:44) Lithium Treatment & Side-Effects

(01:05:05) Effects of Lithium: BDNF, Anti-inflammatory & Neuroprotection

(01:10:10) Neural Circuits of Bipolar Disorder, Interoception, Hyper- vs. Hypoactivity

(01:17:11) Neural States & Mania, Parietal Lobe & Limbic System

(01:22:58) Homeostatic Plasticity, Synaptic Scaling, Lithium & Ketamine

(01:36:00) Talk Therapies: Cognitive Behavioral Therapy, Family-Focused Therapy, Interpersonal & Social Rhythm Therapy

(01:43:18) Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (rTMS)

(01:48:01) Psylocibin, Cannabis

(01:51:50) Lifestyle Support, Supplements: Inositol & Omega-3 Fatty Acids

(02:03:31) Omega-3s, Membrane Fluidity & Neuroplasticity

(02:06:44) Mania, Creativity & Occupations

(02:15:33) Bipolar Disorder: Diagnosis, Neural Circuits & Treatment

(02:17:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Bitcoin Magazine Podcast ✓

Claim

Podcast Notes Key Takeaways * Money and currency are two different things + Money is economic energy, while a currency is a method of moving economic energy across time and space that is typically designated by a government * Fiat currencies are a method of moving economic energy, but they dissipate energy over time + For example, the US dollar dissipates energy at a rate of about 15% per year, and the Turkish Lira dissipates about 70% of its energy per year * Bitcoin could become a $250 trillion ecosystem without threatening any nation state by demonetizing gold, then real estate, then corporate bonds, equities, etc. + It doesn’t have to “replace” anything; it can partner with people, companies, and nations and improve them * “If you want to watch how Bitcoin Hyperization happens, watch how dollarization happens … and does it happen with bloodshot or without bloodshed.” – Michael Saylor + He doesn’t think it’s practical for the world to collectively adopt a Bitcoin standard anytime in the next few decades * As Bitcoin grows and becomes more understood, rational nations will embrace Bitcoin holders, miners, and companies, which will result in more favorable policies toward Bitcoin * “Sound money in the 19th century was gold. Sound money in the 21st century is bitcoin.” – Michael Saylor + Bitcoin is just the introduction of a better technology; it is not “coming to get” anyone or anything * There don’t have to be losers if Bitcoin adoption continues; everyone can win + Instead of “Bitcoin fixes this”, the more appropriate meme is “Bitcoin improves this”

Read the full notes @ podcastnotes.org

Michael Saylor (@Saylor) and Aleks Svetski (@GhostofSvetski) have a long-form conversation about the implications of Bitcoin and its effects on the world we live in today.

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Knowledge Project

Podcast Notes Key Takeaways * “According to me, you can not develop substance, net worth, wealth, experience unless you’re constantly willing to risk your reputation”– Kunal Shah + India supports a business culture of going all-in and has a community to provide you a soft landing if you fail + Many cultures reject even risking 1% of your reputation to pursue a goal or dream * The question “why would somebody pay for this?” varies greatly across cultures + Example: Many people in India have never worked for an hourly wage, so they don’t know the exact value of their time. So as a result, convenience products do not perform well as they do in Western culture. * “Everything that feels soulful in life is inefficient”– Kunal Shah + Emotional arousal rarely happens with efficient metrics + Standardized things are easier to scale, but non-standardized things are harder to destroy * When you have too much similarity, innovation dies. When you have too much dissimilarity, trust dies. + Businesses operate on a spectrum of chaos and stagnation * Like what you’ve read so far? SUBSCRIBE to PODCAST NOTES PREMIUM to get our FULL COVERAGE of this conversation—coming out next week! + “The wisdom per word ratio is off the charts”– Shane Parrish

Read the full notes @ podcastnotes.org

Indian entrepreneur and venture capitalist Kunal Shah calls on his decades of entrepreneurial experience to discuss what he’s learned about what motivates people, and how observing trends have made him a runaway success in business. Shah also discusses the cultural differences between India and the West, the lessons he learned growing up in the family business, why he dropped out of an MBA program, strategies for decision-making, and so much more. Shah is the founder and CEO of CRED, an Indian fintech company that serves as a reward-based credit card payments app. Shah also currently sits on the board of a variety of Indian companies and has served as an investor in dozens of companies since 2016. --

Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Artificial Intelligence Podcast

Podcast Notes Bitcoin * An open, decentralized protocol like Bitcoin returns sovereignty, individualism, and personal responsibility back to the individual and takes it away from institutions * Bitcoin is a savings technology that simplifies wealth preservation and generation for the everyday person * Bitcoin is sound money that exists outside of the current political and monetary system, and it cannot be controlled by governments to benefit the few at the expense of the many * Fiat currencies lose purchasing power over time as governments print more and more of it + Fiat currencies, as they exist today, have only existed for the last 50 years or so * Bitcoin and gold share many of the same monetary properties, but being natively digital, bitcoin has various technological advantages that will make it a better store-of-value asset in the long term than gold * Crypto is an arena of ideas; a war of attrition. + It will be obvious which projects are valuable and which are not ten years from now * Money is time, and the pursuit of money is driven by the belief that more capital accumulation will give the individual more time doing things they enjoy * Happiness is spending your time how you want to spend it + Having more money allows you to spend a larger percentage of your time how you want to spend it

Read the full notes @ podcastnotes.org

Anthony Pompliano is an entrepreneur, investor, writer, and podcaster on topics of decentralized finance. Please support this podcast by checking out our sponsors: – Theragun: https://theragun.com/lex to get 30 day trial – Sun Basket: https://sunbasket.com/lex and use code LEX to get $35 off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Indeed: https://indeed.com/fridman to get $75 credit EPISODE LINKS: Anthony’s Twitter: https://twitter.com/APompliano Anthony’s YouTube: https://www.youtube.com/c/AnthonyPompliano Anthony’s Website: https://anthonypompliano.com/ Pomp Letter: https://pomp.substack.com/ Pomp Podcast: https://anthonypompliano.com/podcast/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT &

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What Bitcoin Did

“I think this decade is going to be transformative, but we’re still too early to say exactly where this ends up or how quickly this goes.”

— Lyn Alden

SHOW DESCRIPTION

Lyn Alden is a macroeconomist and investment strategist. In this interview, we discuss the rise and role of Central Banks: their intermittent role in the US’s history, the piecemeal erosion of a gold standard, the new era of easy money, and whether Bitcoin could replace Central Banking.

Central Banks have played such a dominant role in our societies it’s easy to assume that they are required institutions within modern governmental systems. The idea that the market can determine a monetary policy and the price for money is well outside of the Overton window.

Yet, for long periods in the industrialised era modern civilised societies have functioned, developed and prospered without such institutions. Further, there is ample evidence that central banks are now far from being a steadying force that brings stability to economies.

For around 100 years, the international monetary system was pegged to gold; albeit there were debasements, new controls, and periodic abandonments during this period. Then in 1971, the monetary system was taken off any remnants of a gold standard. Its constraints on US fiscal policy had become too burdensome. It led to the development of fiat currencies and a period of easy money.

Governments have become increasingly dependent upon Central Banks in creating new money to assist with economic shocks: following the global financial crisis the production of dollars markedly increased. But these events were dwarfed by the injection of new money during the pandemic. Inflation is now catching up, but at a time when economies are stagnating.

Cycles of debt accumulation always come to an end. Without careful political judgement, coordination and luck, the resolution of unsustainable debt at the global level can lead to domestic and international conflict. So, we’re entering a transformative decade.

The question is whether Bitcoin, the strongest form of money ever invented, can enable society to navigate through this unwinding of the long-term debt cycle? Additionally, can it enable the market to again determine the price of money?

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Honestly with Bari Weiss ✓

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Podcast Notes Key Takeaways * “The battle for the survival of the United States of America is upon us. It has not come in the form of traditional civil war. There are no uniformed armies, competing flags, or alternate constitutions. The great showdown is not being fought within the physical limits of a battlefield. It is instead happening all around us and directly to us. It defines our culture, sustains our media, and gives new shape to our public and private institutions—it is remaking the nation before our very eyes.”– Bari Weiss quoting Abe Greenwald + The forces of justice and progress are in a war against backwardness and tyranny * Cancel culture is the justice system of the Un-American Revolution: “step out of line, and you could be next” + Tools of oppression that the Un-American ideology uses to deplatform, disinvite, and discredit: Facts replaced by feelings. Excellence is replaced by equity. Rule of law was replaced with the rule of the mob. Continue reading for more examples. + “The Coalition of the Sane” – an allegiance where disagreement doesn’t result in cancellation * Preview of the 10 points of advice Bari Weiss gives to the Future Founders of America: + Defend freedom of speech – The tool that guides us in the search for truth. Be public and vocal in rejecting claims you know to be false. Cowardice is contagious, but so is courage. + Use your own eyes and ears – Narratives work because they are easy and digestible. Facts are just too stubborn to neatly fit into narratives. This is why you must seek out your own truth, and do your own research. You don’t need to be an expert to form your own opinion. + Refuse to submit your friendships and relationships to political litmus tests – The beauty of America is that there are so many realms of life (love, art, friendship) located outside of politics. Don’t submit to totalitarianism. Don’t forget what it means to be human. Not everything is political. + SEE THE 7 OTHER CALLS TO ACTION BELOW

Read the full notes @ podcastnotes.org

There are nearly 4000 universities in the U.S.. Many of them have billions of dollars in endowments and histories that go back to well before the country's founding. So you'd be forgiven for thinking that it would be a bit ridiculous to try and compete with those Goliaths.

But that's exactly what the new University of Austin or UATX is doing. The premise, of course, is simple, and it goes like this. While the brand name schools have the money, they no longer have the mission. They have fundamentally abandoned the point of the university, which is the pursuit of truth. The good people at UATX, where I'm proud to be on the board, are not waiting for the broken status quo to change. They're not sitting around criticizing or whining. They are doing.

Just a few weeks ago, UTAX opened its doors to its first students at its inaugural summer school. I was blown away by the students that I met there, and I was honored to lecture alongside teachers like Neil Ferguson, Kathleen Stock, Ayaan Hirsi Ali, Rob Henderson and Thomas Chatterton Williams. And today I wanted to share with all of you the talk that I gave at the old parkland in Dallas to that first class of students. It's about the broken moment that we're in as a culture and a country, but more it's about what I think is required of us to meet this moment.

Learn more about your ad choices. Visit megaphone.fm/adchoices

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Modern Wisdom

Podcast Notes Key Takeaways * Check out the Modern Wisdom Episode Page & Show Notes

Read the full notes @ podcastnotes.org

To celebrate 500 episodes on Modern Wisdom, I broke down some of my favourite lessons, insights and quotes from the last 4 and a half years.

Expect to learn why having no role models can be an advantage, how discipline eats motivation for breakfast, why you should be training for the difficult, why success in pursuit of happiness can be self-defeating, why fame makes you weak, how an obsession with productivity is just immortality by another name, what I learned about negativity biases from Margaret Thatcher, the importance of letting go of successful habits for new ones and much more...

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Huberman Lab

Podcast Notes Key Takeaways * The inherent goal of the taste system is to get nutrients to survive – attracted to the ones we need, aversion to the ones that may kill us * Taste is predetermined: parts of the brain will experience the full behavioral stimulus, even if activated when only ingesting water * “I don’t believe obesity is a disease of metabolism, I believe obesity is a disease of brain circuits.” – Dr. Charles Zuker * Sugar molecules activate the “gut-brain axis” which drives the preference for sugar * Artificial sweeteners fail to curb the appetite for sugar because they work on the tongue to recognize sweetsness but do not activate sensors in the gut which satisfy the craving * Diseases of malnutrition today are linked to overnutrition (of processed foods), not the actual absence of food * Highly processed foods highjack the gut-brain axis, continuously reinforcing “wanting”

Read the full notes @ podcastnotes.org

My guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world’s leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind.

Thank you to our sponsors

Thesis: https://takethesis.com/huberman

ROKA: https://roka.com/huberman

Helix Sleep: https://helixsleep.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Charles Zuker & Taste Perception

(00:03:05) Momentous Supplements

(00:04:35) Thesis, ROKA, Helix Sleep

(00:08:35) Sensory Detection vs. Sensory Perception

(00:11:48) Individual Variations within Perception, Color

(00:16:20) Perceptions & Behaviors

(00:20:19) The 5 Taste Modalities

(00:26:18) Aversive Taste, Bitter Taste

(00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor

(00:30:14) Additional Taste Modalities: Fat & Metallic Perception

(00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors

(00:39:34) Burning Your Tongue & Perception

(00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence

(00:51:55) Positive vs. Negative Neuronal Activation & Behavior

(00:56:16) Acquired Tastes, Conditioned Taste Aversion

(01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One’s Lifetime

(01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion

(01:17:26) Sensitization to Taste, Internal State Modulation, Salt

(01:24:05) Taste & Saliva: The Absence of Taste

(01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response

(01:36:23) Vagus Nerve

(01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis

(01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite

(01:54:06) Cravings & Gut-Brain Axis

(01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior

(02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods

(02:10:38) Favorite Foods: Enjoyment, Sensation & Context

(02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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My First Million

Podcast Notes Key Takeaways * Talent and resources, that would otherwise be unavailable during an economic boom, become increasingly available during a recession * A founder must convince talented people to do the “irrational thing” and join their startup + Salary is just one vector of value for an employee, and one that people often over-index * There are three types of employees: creatives, completers, and collaborators * The Trillion-Dollar Venn Diagram of Success: create value at the intersection of two of your skills + Acquire skills that are rare and also ones that reinforce the skills that you’re already exceptional at * Most things require skill, not talent * Find what your time is worth on an hourly rate and either don’t do or delegate, any tasks that return a value less than that amount * Creating a successful business requires a big dream and constant iterations on ideas, processes, and products

Read the full notes @ podcastnotes.org

Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk to Co-Founder & CTO of HubSpot, Dharmesh Shah (@dharmesh), about why a bad economy is a good time to start a business, creating an alternative to Wordle, and the trillion dollar Venn diagram of success.

Also, want $5,000? Check out the My First Million Clips contest.

Links:

HubSpot
Why to Start a Startup in a Bad Economy article
WordPlay
Maven writing course
Shaan tweet about starting the next Pixar
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(02:10) - Why renting is better than owning

(25:20) - Framework for three types of employees

(35:05) - Why Dharmesh built WordPlay

(01:07:55) - Driving value through an intersection of skills (Trillion dollar Venn diagram)

(01:12:10) - Why Shaan is starting the next Pixar

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Jocko Podcast

One day you're a team member, and the next day you are the supervisor. How do you handle that position?

Support this podcast at — https://redcircle.com/jocko-podcast/exclusive-content

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The Realignment ✓

Claim

Podcast Notes Key Takeaways * The work that’s gone into building the internet and digital networks over the last 30 years is comparable to the work that went into building the physical networks, like the railroads and highways, during the second industrial revolution period of the 1880s to 1920s * Every historical achievement started as speculation + Today, society is willing to take digital risks but has become extremely adverse to taking analog risks * “Nuclear is by far the safest form of energy [for humans and the environment] that we know how to make.” + But regulators in the U.S. won’t allow new nuclear plants to be built + Starting in the 1970s, the U.S. has basically made it illegal to build real-world infrastructure in a very deliberate way * Americans’ trust in large-scale institutions has declined over the last 50 years, and the primary question is whether social media caused the collapse of trust or simply exposed the rot that previously existed * The future of the internet could involve the creation of networks built from the bottom-up that are more participatory and effective at solving today’s problems, instead of the existing top-down, traditional, hierarchical institutions that are losing the trust of the people * Today, managerial capitalism has overtaken bourgeois capitalism and largely become “capitalism” as we know it + The emergence of venture capital and private equity in the 1970s and 1980s is the “revenge” of bourgeois capitalism * Many of the misconceptions in the crypto space are caused by people working backward from price, when they should be working forwards from fundamentals * Ironically, the three most dysfunctional areas of our current society – housing, education, and healthcare – are also the most critical for achieving the American Dream * The current system has been wired in a way that makes ordinary people so frustrated that they resort to more radical politics + Fixing housing, education, and healthcare would reduce political polarization

Read the full notes @ podcastnotes.org

Subscribe to The Realignment on Supercast to support the show and access all of our bonus content: https://realignment.supercast.com/.

REALIGNMENT NEWSLETTER: https://therealignment.substack.com/

BOOKSHOP: https://bookshop.org/shop/therealignment

Email us at: realignmentpod@gmail.com

This episode and our expanded coverage are made possible thanks to our Supercast subscribers. If you can, please support the show above.

Marc Andreessen, cofounder and general partner at Andreessen Horowitz, cofounder of Netscape, and co-creator of the influential Mosaic web browser joins The Realignment to discuss how the second industrial revolution (1880s-1920s) shapes his view of America today, the consequences of the shift from a high to low institutional trust society, the response to Web3 skeptics, how crashes shape the tech industry, and why it's "time to build."

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Huberman Lab

Podcast Notes Key Takeaways * Adequate quality and duration of sleep and experiencing all the different stages of sleep (i.e., slow wave, REM) are important in optimizing metabolic circuits for health and performance * When done properly (i.e., sleeping and waking at roughly the same time, bright light exposure in the morning, dim lights in the evening, etc.) study participants experienced huge benefits in mood, stress, and grip strength (among other outcomes) when switching habits from “night owl” to “morning person” * Four main neuromodulators: (1) dopamine; (2) epinephrine/adrenaline; (3) serotonin; (4) acetylcholine * Different neuromodulators are naturally present at higher or lower levels in each phase of the day – leverage these natural fluctuations to optimize your focus and outcomes * “Dopamine is not about pleasure, it’s about motivation, craving, and pursuit for goals or things outside our immediate experience or possession.” – Dr. Andrew Huberman * Tools optimize dopamine: sunlight, caffeine, tyrosine, mucuna pruriens, L-tyrosine, phenylehtylamine, cold exposure, B vitamins * Tools to optimize epinephrine: exercise, breathwork (cyclic hyperventilation), caffeine * Tools to optimize acetylcholine: foods rich in choline, nicotine (no, don’t smoke cigarettes), alpha-GPC, huperzine, narrow visual field * Tools to optimize serotonin: physical touch, gratitude, tryptophan, cissus quadrangularis, 5-HTP, myo-inositol * When trying any of the tools listed, start with the behavioral approach, then nutrition, then supplementation, then turn to the clinical/pharmaceutical approach if all else fails or there is a medical necessity

Read the full notes @ podcastnotes.org

In this episode, I explain the biological roles of the four major neuromodulators—dopamine, epinephrine (aka adrenaline), serotonin, and acetylcholine—and describe how these neuromodulators impact a wide variety of mental states and behaviors, including focus, creativity, motivation, drive, learning, alertness, mood, relationships, and feelings of well-being. Then, with that foundational understanding in mind, I describe a potent toolkit of science-supported behavioral, nutrition, and supplementation tools that can be used to increase baseline levels of individual neuromodulators and that can be modified for specific goals. This episode summarizes low-or-no-cost, actionable, science-based tools that can benefit anyone in order to enhance their levels of brain chemicals and improve mental health, physical health, and performance.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Optimizing Neurochemicals to Improve Health

(00:03:40) Momentous Supplements

(00:05:30) Sleep & Maintaining Healthy Metabolism

(00:09:52) Tools: How to Wake Up Earlier, Night Owls

(00:19:32) AG1 (Athletic Greens), Thesis, InsideTracker

(00:22:05) Nervous System Overview

(00:31:32) How Neuromodulators Work

(00:34:24) Baseline Neuromodulator Levels, 3 Daily Phases

(00:42:15) Hormones Modulate Neuromodulators

(00:52:12) The 4 Major Types of Neuromodulators

(01:01:45) Tool Kit 1: Increase Baseline Dopamine & Focus

(01:08:52) Tyrosine-rich Foods & Dopamine

(01:10:59) Dopamine Supplementation: Mucuna Pruriens, L-tyrosine & Phenylethylamine

(01:16:00) Deliberate Cold Exposure & Dopamine

(01:21:12) Tool Kit 2: Additional Tips to Increase Dopamine

(01:26:10) Tool Kit 3: Increase Epinephrine (Adrenaline) & Alertness

(01:34:34) Tool Kit 4: Increase Acetylcholine & Attention/Learning; Choline-rich Foods

(01:37:29) Acetylcholine Supplements: Nicotine, Alpha GPC, Huperzine

(01:44:47) Tool Kit 5: Behavior to Increase Focus & Acetylcholine

(01:46:56) Tool Kit 6: Behavior to Increase Serotonin & Feelings of Well-being

(01:50:51) Tools: Tryptophan-Rich Foods & Serotonin

(01:53:31) Tools: Serotonin Supplements: Cissus Quadrangularis, 5-HTP, Myo-inositol

(02:02:14) Use the Neurochemical Toolkit to Meet Individual Goals

(02:06:44) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Pomp Podcast

Keith Rabois is a General Partner at Founders Fund, A member of the "Paypal Mafia" and has helped build and invest in multiple billion dollar companies.

This audio podcast was pulled from my live event with Keith Rabois at Showfields in Miami, Florida. In this conversation, we talk about the frameworks around critical thinking, including how it's done, changing your mind on closely held beliefs, and the downsides to having so much conviction. We also discuss the macro economy and other current events such as Covid, gun control, Bitcoin and geopolitics.

To see the full video interview of my chat with Keith, go to my Anthony Pompliano YouTube Channel.

=======================

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FTX.US is also the only leading exchange that supports both Ethereum and Solana NFTs.

Download the FTX App today and use referral code “Pomp” to earn free crypto on every trade over $10. The more you trade, the more you earn.

========================

BCB Group is the leading payment services partner for the digital assets industry. BCB Group provides payment services in 30+ currencies, FX, cryptocurrency liquidity, digital asset custody and BLINC, which is BCB’s free, instant settlements network for the BCB client ecosystem.

Find out more by visiting bcbgroup.com/pomp

=======================

Brave Wallet is the first secure crypto wallet built natively in a web3 crypto browser. No extension required. Store, manage, and grow your portfolio, get NFT & multi-chain support, and more.

Download the Brave privacy browser at brave.com/Pomp, and click the wallet icon to get started.

=======================

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Huberman Lab

Podcast Notes Key Takeaways * Learning to engage muscles actively without a load will improve “muscularity” or muscle tone at rest * Train smarter: increase the intensity and reduce the time; workouts generally shouldn’t last more than an hour unless you are lifting heavy and rests are longer * If your goal is general health & fitness, split time 60% strength training (M/W/F) + 40% cardio/conditioning (Tu/Th) * Grip strength is tied to performance & recovery – if you have a decrease in 10% or more of grip strength, you should skip the gym that day * Choose the sleep position that is least abrasive to your body – sleep position affects movement while awake; you can sleep through uncomfortable positions, but the body will incur the strain and stress in wakefulness * Tip: try passive stretching before bed to lengthen muscles before entering a contracted state while sleeping (depending on position) * “Your body is very smart and it’s going to find compensations but that doesn’t mean the compensation isn’t going to leave you with a whole host of other issues.” – Jeff Cavaliere * Lose the nutrition dogma: if you try a nutrition approach that allows you to gain control of your nutrition and health forever, then do it! * Universal nutrition truth: we’d all be better off without the sugar * How to approach eating: largest portion = fibrous carbohydrates (e.g., broccoli, brussels sprouts, asparagus, etc.); second-largest portion = protein (e.g., clean sources – chicken, fish, meat, etc.); smallest portion = starchy carbohydrates (e.g., sweet potatoes, rice, etc.)

Read the full notes @ podcastnotes.org

My guest this episode is Jeff Cavaliere, MSPT CSCS, a world-class physical therapist and Certified Strength & Conditioning Specialist. Jeff has coached athletes ranging from novice to professional and has taught science-based physical training protocols to tens of millions of everyday people via his enormously clear and actionable online programs. Jeff is a true expert on proper resistance and cardiovascular training, injury prevention and rehabilitation and has extensive knowledge on proper form, posture, nutrition and supplementation. We discuss how to best design and optimize a physical training program to achieve your specific goals. We also discuss how to build and leverage mental focus during workouts, when and how to stretch, pain management and enhancing workout recovery and sleep, and how to personalize your training and nutrition program over time. Jeff’s knowledge and science-based approach ought to benefit everyone in reaching their desired fitness, aesthetic and overall health goals.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Eight Sleep: https://www.eightsleep.com/huberman

ROKA: https://www.roka.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Jeff Cavaliere, Physical Training

(00:03:27) Momentous Supplements, AG1 (Athletic Greens), Eight Sleep, ROKA

(00:08:38) Tool: A Fitness Plan for General Health

(00:13:27) Tool: Optimizing Body Part Training Splits

(00:20:12) Two-a-Day Training

(00:22:33) Cardiovascular Conditioning, High-Intensity Interval Training (HIIT) & Skills

(00:28:24) Tool: Mind-Muscle Connection, The Cavaliere Cramp Contraction Test

(00:35:05) “Muscularity” & Resting Tone

(00:41:31) Tool: Muscle Recovery & Soreness, Grip Strength

(00:50:39) Sleep & Sleep Position

(00:57:24) Active (Dynamic) vs. Passive Stretching, Timing & Healing Muscle

(01:07:23) Tool: Jumping Rope

(01:12:56) Internal & External Rotation, Upright Row vs. High Pull

(01:24:27) Back Pain Relief & Medial Glutes, Body Pain & Origins

(01:37:39) Tool: Properly Holding Weights & Deepening Grip

(01:43:54) Tool: Physical Recovery, Heat & Cold Exposure

(01:47:19) Tool: Record Keeping for Training Performance & Rest Time

(01:51:47) Nutrition Principles & Consistency, Processed Foods & Sugar

(02:00:15) Tool: “Plate Eating”: Protein, Fibrous & Starchy Carbohydrates

(02:11:25) Training in Men vs. Women, Training for Kids & Adolescents

(02:18:05) Tool: Pre- and Post-Training Nutrition

(02:26:30) Intensity & Training Consistency

(02:29:53) AthleanX, Jesse Laico & Fitness Journeys

(02:38:27) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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The Rational Reminder Podcast ✓

Claim

Welcome to another episode of the Rational Reminder Podcast, a show helping people to make educated financial decisions and investments. We usually interview an expert on each show however, in this episode, we take a beat and try something different. In today’s jam-packed episode, hear updates regarding our goals survey, the schedule for upcoming guests on the show, the latest news and highlights from the financial world, and some of the feedback we have received about the show. We also highlight interesting articles and papers regarding tech valuations, expected stock returns, the performance of venture capital funds, and a book recommendation that will help you understand the finance game. Tune in to learn about the results of the recent social survey in Canada, the basics of private equity funds, the challenges of calculating the Internal Rate of Returns for investors, some of the misconceptions surrounding private equity, and much more! Don’t miss out on this informative and well-rounded episode of the Rational Reminder Podcast with your two favourite Canadians!

Key Points From This Episode:

We start the show with an exciting announcement for our listeners. [0:02:07]
An update regarding the Goals Survey Project and what needs to be done. [0:03:30]
A rundown of the upcoming guests for the show. [0:04:44]
Outline of the reviews and criticisms received about the show. [0:05:55]
A breakdown of the book for today’s review, Finite and Infinite Games. [0:10:07]
Background about the author of the book, James P. Carse. [0:10:57]
The main point of the book: the differences between finite and infinite games. [0:11:16]
An interesting quote from the book regarding culture. [0:14:42]
Highlights of the recent news and updates in the financial world. [0:17:02]
Insights from an interesting article about tech valuations by Cliff Asness. [0:19:47]
Another interesting paper by David Blitz about expected stock returns. [0:23:09]
A discussion regarding the recent social survey implemented in Canada. [0:26:07]
We discuss the basics of private equity as an investment strategy. [0:30:06]
Why the math used is problematic for calculating the Internal Rate of Return. [0:32:35]
The results of a paper which investigated the performance of venture capital funds. [0:39:01]
More insights from follow-up papers about private equity. [0:42:24]
Examples of the type of risk exposures that private equity provides. [0:49:36]
The impacts associated with the preference for illiquid assets. [0:52:00]
Some of the misconceptions surrounding diversity in private equity funds. [0:52:44]
What are the best metrics to use to measure returns on private equity. [0:56:00]

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Huberman Lab

Podcast Notes Key Takeaways * Hallmark feature of obsessive-compulsive disorder: intrusive obsessions, meaning the person doesn’t want to have them * Every time one engages in a compulsion (action) related to the obsession (thought), the obsession becomes stronger in a powerful and debilitating loop * Suppressing anxiety in the wrong direction to take if trying to relieve or eliminate OCD * The goal of cognitive behavior therapy in the context of OCD is to uncover the underlying fear driving the OCD – then take the patient to the highest anxiety point to disrupt the neural circuit between the processing and action parts of the brain to tolerate the anxiety and avoid the compulsion * The most helpful treatment routes are either cognitive behavioral therapy alone or adding cognitive behavioral therapy to an existing SSRI protocol (treatments take 10-12 weeks for full effect) * Obsessive-compulsive personality disorder: delayed gratification people want or enjoy because it allows them to function better and or in line with how they would like to present themselves * Superstitions: a belief that we are affecting the probability of an outcome when we truly know in our rational minds that there is no real relationship to the outcome

Read the full notes @ podcastnotes.org

In this episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD)—a prevalent and debilitating condition. I also discuss the efficacy and mechanisms behind OCD treatments—both behavioral and pharmacologic as well as holistic and combination treatments and new emerging treatments, including directed brain stimulation. I explain the neural circuitry underlying repetitive “thought-action loops” and why in OCD, the compulsive actions merely make the obsessions even stronger. I review cognitive-behavioral therapies like exposure therapy and SSRIs, holistic approaches, and nutraceuticals, detailing the efficacy of each approach and what science says about how to combine and sequence treatments. I describe an often effective approach for treating OCD where clinicians use cognitive behavioral therapy (CBT) to deliberately bring patients into states of high anxiety while encouraging them to suppress compulsive actions in order to help them learn to overcome repetitious thought/action cycles. This episode should interest anyone with OCD, anyone who knows someone with OCD or OCPD, and more generally, those interested in how the brain works to control thoughts and actions, whether those thoughts are intrusive or not.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

Eight Sleep: https://www.eightsleep.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Obsessive-Compulsive Disorder (OCD)

(00:03:01) Momentous Supplements, AG1 (Athletic Greens), Thesis, Eight Sleep

(00:08:28) What is OCD and Obsessive-Compulsive Personality Disorder?

(00:11:18) OCD: Major Incidence & Severity

(00:15:10) Categories of OCD

(00:21:33) Anxiety: Linking Obsessions & Compulsions

(00:27:33) OCD & Familial Heredity

(00:29:10) Biological Mechanisms of OCD, Cortico-Striatal-Thalamic Loops

(00:39:36) Cortico-Striatal-Thalamic Loop & OCD

(00:46:39) Clinical OCD Diagnosis, Y-BOCS Index

(00:51:38) OCD & Fear, Cognitive Behavioral Therapy (CBT) & Exposure Therapy

(01:01:56) Unique Characteristics of CBT/Exposure Therapy in OCD Treatment

(01:10:18) CBT/Exposure Therapy & Selective Serotonin Reuptake Inhibitors (SSRIs)

(01:22:30) Considerations with SSRIs & Prescription Drug Treatments

(01:25:17) Serotonin & Cognitive Flexibility, Psilocybin Studies

(01:31:50) Neuroleptics & Neuromodulators

(01:36:09) OCD & Cannabis, THC & CBD

(01:39:29) Ketamine Treatment

(01:41:43) Transcranial Magnetic Stimulation (TMS)

(01:46:22) Cannabis CBD & Focus

(01:47:50) Thoughts Are Not Actions

(01:51:27) Hormones, Cortisol, DHEA, Testosterone & GABA

(02:00:55) Holistic Treatments: Mindfulness Meditation & OCD

(02:03:28) Nutraceuticals & Supplements: Myo-Inositol, Glycine

(02:09:45) OCD vs. Obsessive-Compulsive Personality Disorder

(02:20:53) Superstitions, Compulsions & Obsessions

(02:31:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Beginner's Mind ✓

Claim

Podcast Notes Key Takeaways * A challenge to mental health drug development is that people with the same mental health disorder do not necessarily exhibit the same biological signs and symptoms * Prior to exploration and innovation with psychedelics, mental health treatment has not made significant advancements since the invention of SSRIs in the 1980s * Big pharma is not necessarily interested in psychedelics because they don’t know how to fit into the current business model – they can’t make money as is since there’s no inherent innovation or IP * Gilgamesh Pharmaceutical is working to create new molecules and psychedelic-like drugs based on the properties of psychedelics but with greater control over dose, experience, time, etc. * If successful, Gilgamesh’s approach could open the door to increased access to psychedelic-like therapies without the need for clinical supervision * Machine learning may provide an avenue to match patients with the correct drug

Read the full notes @ podcastnotes.org

These days many sources are highlighting the shocking scale of the global mental health crisis and how this affects approx—a staggering one billion people worldwide - over one-seventh of the global population.

“Unfortunately, as harrowing and monstrous this number is”, the investor Christian Angermayer wrote in a blog post, “it is my belief this is a gross UNDER-estimate.”

Ultimately, the number of people needing mental health support is arguably all 100% of the world's population.

I invited Dr. Jonathan Sporn, CEO of Gilgamesh Pharmaceutical, to gain more insights into the unmet medical need in mental health and the promising novel psychedelic drug development sector

Jonathan Sporn MD is a Board Certified Psychiatrist, assistant professor at Columbia University, and CEO of Gilgamesh Pharmaceuticals, based in NYC, which is developing novel psychedelic-related or inspired medicines to treat mental illness.

Topics we discuss in this episode:

➡️ Global Mental Health Situation
➡️ The History of Psychedelic Drug Development
➡️ Investors in this promising area
➡️ The Background Story to the foundation of Gilgamesh Pharmaceutical and
➡️ And the Different Ingredients Needed to Structure a Novel Game-Changing Drug Development Company

Connect with Jonathan Sporn on Linkedin
Youtube Video

🕒 Timestamps:
(00:00) Introduction to Topic, Speaker, and Company
(04:00) Life in New York in 2022
(07:15) The Global Mental Health Pandemic
(10:39) Mass Shootings in the United States as a result of the Mental health Situation
(14:05) Why is it Necessary to Develop Novel Drugs to Fight Mental Health Issues in Society
(19:00) The History of Drug Development for Mental Health Patients
(24:00) How Effective Are Psychedelic Drugs to Tackle Mental Health Questions?
(25:05) Psychedelic Drugs in Pop Culture
(26:40) What Inspired Jonathan Sporn to Dedicate His Professional Life to Advance R&D in Psychedelic Drugs
(29:30) Psychedelic Drugs Help to Observe Own Behaviour
(32:30) Root Causes of Mood Disorders like Maniac Depression, Bipolar Disorder
(34:05) Psychedelic Drugs Enhance Neuroplasticity
(36:50) From Basic Research to Drug Development in the Pharma Industry
(40:10) Mental Health R&D at J&J
(43:40) S-Ketamine vs. K-Ketamine – Difference and Similarities
(46:35) Early-Stage Research in Big Pharma
(49:00) Big Pharma and Small Biotechs
(51:50) The decision to Start A New Company
(57:00) Foundation of Perception Neuroscience – From Early Stage Research to Clinical Phase 2 to Exit
(59:05) Atai Life Science – Continuing Development of the Compounds against Depression
Supporting links:
(01:00:00) Reasons for Becoming a Serial Entrepreneur After a Successful Exit Deal
(01:06:00) Drug Development is Simple – Given an Experienced Drug Development Team
(01:08:00) What is the unique approach of Gilgamesh Pharmaceutical?
(01:10:15) Target Product Profile of Psychedelic Drugs
(01:20:30) Gilgamesh Pharmaceuticals Mission and Vision
(01:23:20) Patents in Psychedelic Drug Development
(01:24:45) Business Model of Gilgamesh Pharmaceutical
(01:29:00) Artificial Intelligence in Psychedelic Drug Development
(01:33:14) Investing in the Psychedelic Drug Development Industry
(01:37:22) Life Science VCs in the Psychedelic Drug Development Industry
(01:39:00) Christian Angermayer, Peter Thiel, Mike Novogratz – Investors in Psychedelic Drug Development
(01:41:00) Investment Sentiment in the United States in Developing Novel Innovation
(01:43:00) Opinions on the Investment Market Situation in 2022+
(01:49:40) Gilgamesh Pharma Plans for the Coming Years

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * “More than half of U.S. adults will be classified as actually having obesity at some point in their life if the current context is maintained. You see the same thing with type 2 diabetes.” – Dr. Stephan Guyenet * There is no demographic in the U.S. adults where we have not gotten much fatter over the last few decades – regardless of income, education, or geography – we’re getting fatter than we were * Obesity is highly heritable (about 75%) and preserved * Differences in body fatness between individuals are primarily determined by differences in how the brain is constructed and operates * Any time you eat something sweet, that food substance causes neuropod cells in the gut to send parallel signals to the brain which activates dopamine and tells us to seek out and eat more sweet foods * Dietary tribal ideology can hold you back from finding the right foods for your body * The distribution of fat in the body is more related to insulin signaling; the total amount of fat in the body is related to energy intake * The types of foods most addictive are generally a mix of carbohydrates and fat in optimal concentration which triggers dopamine and activates seeking behavior * When it comes to nutrition, author credentials are not indicative of the quality of information and publishers do not fact-check – be diligent and unbiased in your review or check out Red Pen Reviews (free to public)

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Stephan Guyenet is a neuroscientist focused on the neuroscience of obesity and energy homeostasis. He is the author of the book, The Hungry Brain and founder/director of Red Pen Reviews. In this episode, Stephan explains how obesity has changed phenotypically over the course of human history as well as what might explain the dramatic increase in prevalence of obesity in the last few decades. He talks in depth about the role of genetics, the brain, and hormones like leptin play in the regulation of fat mass. He dives deep into two common theories of obesity—the carbohydrate-insulin model and the energy balance model and provides his take on which theory has stronger evidence. Additionally, he provides insights on how we’re hard-wired to think about food and the consequences of modern foods designed for maximal pleasure. Finally, he goes through the factors that affect body weight, set points, and provides takeaways for people wanting to take advantage of what we know about the brain’s role in regulating our body weight.

We discuss:

Stephan’s neuroscience background and his focus on the nuances of obesity [2:15];
How obesity has changed for humans throughout history [8:00];
The association between obesity and adverse health outcomes, the “obesity paradox,” and confounders when relating BMI to longevity [14:00];
The sharp increase in obesity across demographics [23:30];
The hypothalamus and its role in obesity [30:00];
The role of the hormone leptin in obesity [40:00];
The genetic component of obesity [46:30];
Understanding the tendency of humans to store fat through an evolutionary lens [57:00];
The hedonic aspect of food, and how the brain reacts to modern, highly-rewarding foods [1:03:30];
How we are hard-wired to think about food [1:14:30];
A review of the “Carnivore diet” [1:21:45];
The energy balance model, carbohydrate-insulin model, and unifying the theories around adiposity [1:34:15];
Body weight set points: a hypothetical comparison of two individuals [1:41:45];
Takeaways for people who want to lose weight and keep it off [1:48:30];
Evidence that favors the energy balance model of weight gain [1:56:00];
The synergistic effect of fat and carbohydrates and observations that a low-fat diet or a low-carb diet can cause weight loss [2:04:30];
Red Pen Reviews [2:11:00];
More.

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Art of Manliness

Podcast Notes Key Takeaways * Check out The Art of Manliness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

A lot of young men today struggle in finding their footing in adulthood. They feel lost, directionless, and unsure of who they are and how to confidently and competently navigate the world.

Part of the reason for this is that most young men today lack something which was once a part of nearly every culture in the world, but has now almost entirely disappeared: a rite of passage.

My guest today didn't want his son to flounder on the way to maturity, nor to miss out on having an initiation into manhood, so he set out to create a 6-year journey for him that would help him move from boy to man. His name is Jon Tyson, and he's the author of The Intentional Father: A Practical Guide to Raise Sons of Courage and Character. Today on the show, Jon unpacks the components of the years-long journey into manhood he created for his son, beginning with how he brainstormed those components by doing "The Day Your Son Leaves Home" exercise. We then discuss how old Jon's son was when he started his rite of passage and why it began with him having a "severing dinner" with his mom. We get into what his rite of passage consisted of, from the kickoff ceremony to the challenges, experiences, trips, and daily rituals Jon used to impart values and teach his son the "5 Shifts of Manhood." Jon shares how moving his son's focus from being a good man, to being good at being a man, helped him get remotivated to continue the process, why his rite of passage included a gap year after high school, and how Jon celebrated the end of his son's journey into becoming a man. We also discuss whether Jon did something similar with his daughter. We end our conversation with some key principles any dad can use to start intentionally helping their kids become well-rounded individuals who can confidently step out on their own and into the world.

Resources Related to the Podcast AoM Article: The Importance of Fathers * AoM Article: The Importance of Male Rites of Passage * AoM Article: Male Rites of Passage From Around the World * AoM Article & Podcast: Man’s Need for Ritual * AoM Series on the origins, elements, and future of manhood * AoM Article: The 7 Habits — Begin With the End in Mind * AoM Article: The 3 Families Every Young Man Needs to Grow Up Well * James Hollis * AoM Article: Carry the Fire * Art of Manliness' Carry the Fire Zippo Lighter * AoM Article: What Is Manliness? * AoM Podcast #527 With Richard Rohr * The Power of Moments: Why Certain Experiences Have Extraordinary Impact by Chip and Dan Heath * The Way of Men* by Jack Donovan * AoM Podcast #49 With Jack Donovan * AoM Series on the Four Archetypes of the Mature Masculine * AoM Article: 100 Skills Every Man Should Know * AoM Article: 80+ Quotes on Men & Manhood

Connect With Jon Tyson* Primal Path * Jon on Twitter * Jon on IG

The Power of Moments: Why Certain Experiences Have Extraordinary Impact

The Intentional Father: A Practical Guide to Raise Sons of Courage and Character

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Art of Manliness

Travel can offer a lot of good: memory-making adventure, mind-expanding experiences, and plenty of fun and relaxation. It's not surprising then that most people say they'd like to travel more than they do. What's keeping them from fulfilling that desire? Well, one obstacle, especially these days, is that the high price of plane tickets puts flying out of reach.

My guest today can help you surmount this obstacle so you can get away more often. His name is Scott Keyes, and he's the founder of Scott's Cheap Flights and the author of Take More Vacations: How to Search Better, Book Cheaper, and Travel the World. Today on the show, Scott shares how scoring cheap flights can help you travel more often, the advantages of taking more frequent vacations, and the psychological benefit of planning your trips well in advance. We then get into the misconceptions people have about ticket pricing. From there we turn to Scott's strategies for booking cheap flights, beginning with why he recommends adopting a "Flight First" rather than "Destination First" approach. Scott shares the "Goldilocks" time window when cheap flights are most likely to pop up, the benefits of building flexibility into your itinerary, the days that are typically cheapest to fly, and his favorite search site to look for flights. He also explains how to use the 24-hour rule and Southwest Airlines as arbitrage in getting better prices on your tickets, and how to employ what he calls the "Greek Islands Strategy" to save money when flying internationally. We end our conversation with how to take advantage of "mistake fares," and whether the high prices you're seeing this summer are here to stay.

Connect With Scott Keyes* Scott's Cheap Flights * Scott on Twitter

Take More Vacations: How to Search Better, Book Cheaper, and Travel the World

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Huberman Lab

Podcast Notes Key Takeaways * The opportunity for movement comes from deep within our bodies, we’re always in an anticipatory state of movement * Don’t overthink and overly constrain movement – approach movement practice with play and exploration * Much value of movement practice is interaction with someone else: don’t forget to incorporate touch & remove certain reactivity by exploring closer proximity * Gathering around movement is culturally traditional, strengthens bonds, and builds community (today’s modern equivalent is a gym buddy or yoga friend) – try communicating with a loved one through movement instead of eating and drinking * Dynamic nature of movement & evolution: we go from unskilled to skilled to mastery to virtuosity (true freedom, inviting variability and chance back in to try new things) * Visualization may not be helpful unless you’ve developed tangible experience reinforced by feedback * Bins of perspective are helpful in analyzing movement practice – are you moving towards or away from the following: (1) contraction/relaxation; (2) martial; (3) environment; (4) somatic/internal practice; (5) object manipulatory * Bins of perspective are helpful in analyzing movement practice – are you moving towards or away from the following: (1) contraction/relaxation; (2) martial; (3) environment; (4) somatic/internal practice; (5) object manipulatory * Consider infusing more movement in your current exercises – for example, step and bicep curl instead of standing still

Read the full notes @ podcastnotes.org

My guest is Ido Portal, the world’s foremost expert on human movement. Ido has spent a lifetime studying, combining and evolving elements from an enormous range of martial arts, dance genres, athletic endeavors, and science, to develop a unified theory and practice of movement called “The Ido Portal Method.” Here we discuss all things movement, including the role of the nervous system, reflexive versus deliberate movement patterns, and the link between emotions and awareness in movement. We also discuss learning and neuroplasticity, the mind-body connection and how movement itself can be leveraged toward expanding other types of skills- cognitive, creative and otherwise. As one of the most sought out teachers of movement alive today, the knowledge Ido shares in this conversation can benefit everyone—children, adults, athletes, dancers, clinicians and trainers and the everyday person.

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Timestamps

(00:00:00) Ido Portal, Movement & Movement Practice

(00:03:30) AG1 (Athletic Greens), ROKA, Helix Sleep

(00:07:49) What is Movement?

(00:10:56) Movement & the Body-Mind Connection

(00:14:47) Entry Points to Movement

(00:18:08) Early Education in Movement: Awareness, Play & Examination

(00:21:19) Stillness, Movement & the Environment, Playfulness

(00:31:34) Unique Postures, Types of Movement, Contents vs. Containers

(00:40:50) Discomfort: Marker of Movement, Failures & Learning

(00:47:05) Movement Diversity, Squat Challenge, Injury, Movement Evolution

(00:56:36) Animal & Human Movements, Gain & Change

(01:02:04) Core Movement, Emotion & Memory, Spinal Waves, Evolution

(01:12:39) Song, Dance & Complex Language, Movement as Language, Consilience

(01:21:39) Movement Culture, Community, Collective Knowledge, Wild & Wise

(01:26:36) Potential for Movement, “Humming”

(01:32:18) Instructiveness vs Permissiveness, Degrees of Freedom

(01:35:50) Variety, Diversity & Virtuosity

(01:38:06) Vision & Movement, Focus & Awareness, Panoramic Awareness

(01:48:28) Hearing & Movement

(01:52:43) Walking Gaits

(01:56:55) Playful Variability & Evolution, Improvisation & Openness

(02:03:05) Reactivity & Personal Space, Touch & Proximity to Others, Play & Discomfort

(02:18:13) Visualization & Experience, Feedback

(02:20:14) Linear Movement & Movement Investigation, Examination

(02:31:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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Huberman Lab

Podcast Notes Key Takeaways * Two main mechanisms of flexibility: (1) the first senses when stretch is too much and signals muscle contraction back into place; (2) the second senses excessive load and shut down the ability to contract muscles for safety * Without intervention, age-related declines in the range of motion (average of 1% per year) are inevitable unless you deliberately work on it * A consistent stretching practice can improve range of motion and offset the age-related decline * A dedicated range of motion practice increases flexibility and also improves posture, reduces pain, improves gait, etc. * Superset exercises of antagonistic muscle groups (e.g., push/pull) will offset muscle fatigue as compared to straight sets (completing all sets of push-ups before moving on to pull-ups) * All forms of stretching (dynamic, ballistic, static, PNF) will improve limb range of motion but static stretching post-training session or calisthenics gives the greatest gains * Stretching protocol: 2-4 sets of 30-second hold static stretches totaling 5 minutes, 5 days per week * Ballistic and dynamic stretches are useful for improving performance but won’t necessarily increase limb range of motion as much as static stretching

Read the full notes @ podcastnotes.org

In this episode, I explain the science behind limb range of motion and flexibility and how to increase them by using science-supported protocols. Flexibility is crucial for physical movements and can help prevent injuries, decrease inflammation, modulate physical and mental pain, impact exercise recovery speed and even potentially slow the progression of certain diseases. I explain the biology of flexibility, including the specific neural mechanisms that sense stretch and load (i.e., tension) on the muscles and limbs, as well as how specific brain regions like the insula combine those signals to ultimately control limb range of movement. I also provide science-based stretching and “micro-stretching” protocols that reliably improve limb flexibility with the minimum necessary time investment. I review all the details of those stretching protocols: how often to do them, for how long, their timing relative to other exercises, sets, the time between sets, measuring progress and more. All people, physically active or not, should benefit from the information and tools described in this episode.

Thank you to our sponsors

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Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Flexibility & Stretching

(00:02:57) Thesis, InsideTracker, Eight Sleep

(00:07:22) Innate Flexibility

(00:09:23) Movement: Nervous System, Connective Tissue & Muscle; Range of Motion

(00:17:51) Golgi Tendon Organs (GTOs) & Load Sensing Mechanisms

(00:20:20) Decreased Flexibility & Aging

(00:22:38) Insula, Body Discomfort & Choice

(00:30:02) von Economo Neurons, Parasympathetic Activation & Relaxation

(00:42:00) Muscle Anatomy & Cellular ‘Lengthening,’ Range of Motion

(00:47:16) Tool: Protocol - Antagonistic Muscles, Pushing vs. Pulling Exercises

(00:51:57) Types of Stretching: Dynamic, Ballistic, Static & PNF (Proprioceptive Neuromuscular Facilitation)

(00:59:36) Tool: Increasing Range of Motion, Static Stretching Protocol, Duration

(01:05:56) Tool: Static Stretching Protocol & Frequency

(01:13:55) Tool: Effective Stretching Protocol

(01:17:12) Tool: Warming Up & Stretching

(01:19:17) Limb Range of Motion & General Health Benefits

(01:25:30) PNF Stretching, Golgi Tendon Organs & Autogenic Inhibition

(01:31:23) Tool: Anderson Protocol & End Range of Motion, Feeling the Stretch

(01:32:50) Tool: Effectiveness, Low Intensity Stretching, “Micro-Stretching”

(01:41:33) Tool: Should you Stretch Before or After Other Exercises?

(01:45:41) Stretching, Relaxation, Inflammation & Disease

(01:51:37) Insula & Discomfort, Pain Tolerance & Yoga

(02:00:36) Tools: Summary of Stretching Protocols

(02:03:00) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * “Don’t confuse the optimal diet for you in a state of health with the optimal diet for you in a state of sickness that’s trying to restore your health.” – Dr. Peter Attia * Diet is highly individualized: the reality is we really can’t say that fruit and vegetables themselves are objectively and inherently healthy * Metabolic syndrome is when you have three or more of the following: (1) truncal obesity; (2) high blood pressure; (3) high fasting glucose; (4) high fasting triglycerides; (5) low HDL cholesterol

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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In this “Ask Me Anything” (AMA) episode, Peter discusses the nutritional profiles of various fruits and vegetables as a means of assessing their relative value. He explains the difference between eating them vs. drinking them, how processing fruits and vegetables can change their properties, and how one’s current state of health affects nutrition strategy when it comes to fruits and vegetable consumption. Additionally, Peter explains the potential benefits and negative effects of certain phytochemicals found in produce and concludes with a discussion of supplementing with green powders, multivitamins, and more.

If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #36 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.

We discuss:

The limitations of nutritional data and challenges of making broad recommendations [2:00];
How one’s current state of health impacts their “optimal” diet [11:30];
Defining “metabolic health” [14:45];
The wide-ranging nutrition profiles of various fruits and vegetables [16:30];
The benefits of fiber [20:45];
Eating whole fruits vs. drinking fruit juice or smoothies [22:30];
Drinking alcohol: metabolic effects, calories in alcohol, and more [28:30];
Can excess fruit consumption lead to insulin resistance? [30:30];
Glycemic impact of different fruits, using CGM data to assist decision making, and how fruit is fundamentally different from what we evolved to eat [31:30];
Dietary approaches for people with a carbohydrate tolerance disorder (TD2, NAFLD, etc.), and when it makes sense to restrict fruit consumption [34:30];
Nutrition profile of select vegetables: sugar content, micronutrients, and more [40:00];
Phytochemicals in produce: potential positive health impacts on inflammation, cardiovascular (CV) risk, and cancer [44:30];
Phytochemicals with potential negative health impacts [50:45];
Nightshades and inflammation [53:15];
How important is it to eat organic foods? [56:00];
How necessary is it to wash fruits and vegetables? [1:00:45];
How does food preparation change the nutritional composition? [1:03:45];
Considerations when eating canned and frozen food, and paying attention to processed food additives [1:04:45];
Supplementing vitamins and nutrients as an alternative to eating whole fruits and vegetables [1:06:15];
Green powder supplements [1:11:15];
Important takeaways [1:16:00]; and
More.

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The Hustle Daily Show✓Claim

Podcast Notes Key Takeaways * “Whenever you’re living through a time that you haven’t lived through before, you might want to check history”– Ray Dalio + Dalio’s recent book,The Changing World Order, looks at where the United States is on the historical 18-step curve for the rise and fall of an empire * Ray Dalio’s main points on what’s driving the debt crisis: + Creation of enormous amounts of debt and the printing of money to monetize that debt. “My generation has borrowed a lot of money and left the next generation with a broken-down infrastructure.” – Ray Dalio + Internal political and ideological conflict. Is it hard to imagine that neither side will accept losing in 2024? + International power equivalency and reorganization. The gap is narrowing for the United States as the world’s economic and military superpower. + Continue reading for elaboration on these points, as well as comments on the state of capitalism and the wealth gap * “The amount of value in financial wealth (stocks, bonds, etc.) dwarfs the total amount of real wealth, and that’s a problem because there’s no purpose in financial wealth other than to buy real wealth”– Ray Dalio + When this ratio gets too large, you get monetary inflation + Dalio believes there is an open competition for what real wealth asset will emerge as the best store of wealth * Pain + Reflection = Progress + Mistakes are opportunities to learn. Humility balances audacity.

Read the full notes @ podcastnotes.org

Ray Dalio is the founder and co-chief investment officer of Bridgewater, the largest hedge fund in the world. He’s one of the 100 richest people on Earth. He’s also a best-selling author.

In today’s episode, Zachary Crockett chats with Dalio about his latest book, “The Changing World Order,” which uses a historical lens to examine why empires rise and fall — and why the US may be showing some signs of decline.

We cover a range of topics about the economy and Dalio’s life, including:

The 3 biggest issues America is facing right now

What’s driving the debt crisis

The growing wealth gap (and what we should do about it)

Thoughts on inflation and an impending recession

What to invest in during times of volatility

Whether or not crypto can become a reserve currency

Dalio’s worst failures as an investor

Common traits of successful people

The role luck plays in reaching the top

How Dalio helped McDonald’s launch chicken nuggets

Thank You For Listening to The Hustle Daily Show. Don’t forget to hit Subscribe or Follow us on Apple Podcasts so that you never miss an episode! If you want this news delivered to your inbox, join millions of others and sign up for The Hustle Daily newsletter, here: https://thehustle.co/?utm_source=hustle-daily-podcast&utm_medium=referral&utm_campaign=show-notes

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The Hustle Daily Show is brought to you by The Hustle in partnership with HubSpot Podcasts.

Principles for Dealing with the Changing World Order: Why Nations Succeed and Fail

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Modern Wisdom

Gurwinder Bhogal is a programmer and a writer.

Gurwinder is one of my favourite Twitter follows. He’s written another monstrous thread exploring human nature, cognitive biases, mental models, status games, crowd behaviour and social media. It's one of the best things I've read this year, so I just had to bring him on.

Expect to learn why stupidity is more dangerous than evil, why most content has to appeal to midwits, why political debates are essentially mass-scaled ventriloquizism, how lower stakes lead to more vicious arguments, why the word retard is a strange choice as an unspeakable slur, why being a mess is more likeable than being perfect and much more…

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BulletProof Radio

Podcast Notes Key Takeaways * “Air is as important as food”– Dave Asprey * When your mouth breathes, your lungs act as an external organ + Everything in your environment (pollution, pollen, etc.) can enter your lungs + Your nose performs as a natural filter for the air you breathe * We need to breathe in line with our metabolic needs, which is almost always less and slower than you would think + The tingling sensation you get from heavy fast breathing is from a decrease in circulation, not an increase in oxygen * We take 20,000 to 25,000 breaths per day – if you’re breathing inefficiently, it’s going to catch up with you + Always breathe through your nose and breathe less air + Exercise: Try multiple times a day to only take 6 breaths per minute (5-second inhale, 5-second exhale). This will help improve your functional breathing patterns. + Take the BOLT test: Learn more below

Read the full notes @ podcastnotes.org

IN THIS EPISODE OF THE HUMAN UPGRADE™...

… you’ll learn why every breath you take makes a difference in how your entire body functions. The way you breathe affects the quality of your life and every one of your body systems. Full stop. This goes for adults and kids alike.

In this special edition, breathing experts Patrick McKeown (“THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life”) and James Nestor (“Breath: The New Science of a Lost Art”) approach the topic from diverse perspectives, but agree on a lot. Especially the benefits of nose breathing and the detriment of mouth breathing.

They explain the biochemical, biomechanics and psychological components of how you breathe. They also present exciting new research in pulmonology, psychology, biochemistry and human physiology that shows how making even slight adjustments to the way you inhale dramatically influences things like:

sleep and snoring
fitness and athletic performance
brain function
focus and concentration
oxygen intake
heart rate and blood pressure
blood sugar
internal organ function
nervous system
respiratory health
asthma and allergies
autoimmune disease
sex
female hormones
pain
stress and anxiety

That's just the start of what you can change when you change your breathing. Big claims, yes. All true. And even bigger benefits for you.

Breathing can nurture your body, center you, and rebalance you. When you start harnessing the power of your breath, you're going to feel incredibly better than you do right now.

Patrick McKeown, an author, educator and one of the world’s leading breathing re-education experts, has researched breathing for more than two decades. Listen to more: Shut Your Mouth! Nose Breathing Improves All Your Body Systems – Patrick McKeown – #835

James Nestor, a San Francisco-based science journalist, author, surfer, free diver, adventurer, and speaker, set out on a decade-long quest to find out where our breathing went wrong—and how to fix it. Listen to more: Breathing Essentials That Will Change Your Life – James Nestor – #751

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THE BREATHING CURE: Develop New Habits for a Healthier, Happier, and Longer Life

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Masters in Business

Arnold Schwarzenegger, the movie star-turned-California governor, has been interested in business since long before he was Conan or the Terminator. For more than four decades, his behind-the-scenes partner has been Paul Wachter, whose Main Street Advisors was born 25 years ago, with Schwarzenegger's encouragement.

The modern multihyphenate -- think LeBron, Drake, Billie Eilish -- are following a template the pair established in the 1980s, as Schwarzenegger successfully expanded his popularity and wealth through savvy dealmaking. The key element: Don't just endorse when you can own a piece of the product.

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Huberman Lab

Podcast Notes Key Takeaways * Trauma is an event that rises to the magnitude of overwhelming our coping skills and changing our brain * Trauma is an example of our wiring not serving us well – the guilt and shame associated with trauma cause us to avoid the event (opposite of what we need to do) * The brain tries to make sense of the trauma by recreating the situation and trying to “make it right” this time to relieve the suffering (a process called repetition compulsion) * Memories don’t have inherent meaning – it’s the emotion attached to them that changes our view of events * “When logic and emotion come head to head, emotion wins all the time. It’s powerful enough it will always win.” – Dr. Paul Conti * By bringing trauma to the surface by attaching words, we remove its power * The core tenant of a good therapist is your rapport – an effective therapist will change their modality based on your needs without being dogmatic * Take ownership of your therapy and journey! If your needs aren’t being met, find someone else * Our healthcare system is focused on short-term soothing (e.g., prescription drugs) at the expense of long-term benefit – physicians are quick to throw medication at a problem instead of exploring the root

Read the full notes @ podcastnotes.org

My guest this episode is Dr. Paul Conti, M.D., a psychiatrist and expert in treating trauma, personality disorders and psychiatric illnesses and challenges of various kinds. Dr. Conti earned his MD at Stanford and did his residency at Harvard Medical School. He now runs the Pacific Premiere Group—a clinical practice helping people heal and grow from trauma and other life challenges. We discuss trauma: what it is and its far-reaching effects on the mind and body, as well as the best treatment approaches for trauma. We also explore how to choose a therapist and how to get the most out of therapy, as well as how to do self-directed therapy. We discuss the positive and negative effects of antidepressants, ADHD medications, alcohol, cannabis, and the therapeutic potential of psychedelics (e.g., psilocybin and LSD), ketamine and MDMA. This episode is must listen for anyone seeking or already doing therapy, processing trauma, and/or considering psychoactive medication. Both patients and practitioners ought to benefit from the information.

Thank you to our sponsors

ROKA: https://www.roka.com/huberman

InsideTracker: https://insidetracker.com/huberman

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Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Paul Conti, Trauma & Recovery

(00:02:30) ROKA, InsideTracker, Blinkist

(00:07:00) Defining Trauma

(00:14:05) Guilt & Shame, Origins of Negative Emotions

(00:21:38) Repeating Trauma, the Repetition Compulsion

(00:28:23) How to Deal with Trauma & Negative Emotions/Arousal

(00:37:17) Processing Trauma, Do You Always Need a Therapist?

(00:45:30) Internal Self-talk, Punishing Narratives & Negative Fantasies

(00:51:10) Short-Term Coping Mechanisms vs. Long-Term Change

(00:53:22) Tools: Processing Trauma on Your Own, Journaling

(00:57:00) Sublimination of Traumatic Experiences

(01:02:34) Tool: Finding a Good Therapist

(01:07:20) Optimizing the Therapy Process, Frequency, Intensity

(01:14:51) Tool: Self-Awareness of Therapy Needs, Mismatch of Needs

(00:16:35) Self-talk & Journaling, Talking to Trusted Individuals

(01:19:00) Prescription Drugs & Treating Trauma, Antidepressants, Treating Core Issues

(01:28:35) Short-term vs. Long-Term Use of Prescription Drugs, Antidepressants

(01:32:18) Attention Deficient Hyperactivity Disorder (ADHD) & Prescription Drugs

(01:37:31) Negative Effects of ADHD Prescription Drugs

(01:40:37) Alcohol, Cannabis – Positive & Negative Effects

(01:44:53) Psychedelics: Psylocibin & LSD, Therapeutic Uses, Trauma Recovery

(01:54:32) Sentience, Language, Animals

(01:55:48) Psychedelic Hallucinations, Trauma Recovery

(02:00:01) MDMA (Therapeutic Uses)

(02:04:47) Clinical Aspects of MDMA

(02:07:28) Language, Processing Trauma, Social Media, Societal Divisions

(02:15:09) Defining “Taking Care of Oneself”

(02:21:13) Dr. Conti, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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Modern Wisdom

Podcast Notes Key Takeaways * “There is much more talent to tap into than ever before, but in most parts of the world, we are screwing it up”– Tyler Cowen + “We’re rewarding homework at every stage of the process, and then we’re shocked when we get too many conformists” – Tyler Cowen + Credentialism, seniority requirements, bureaucratized evaluations, and conservative HR departments also contribute to the hiring problem * Tyler’s definition of talent: people with an energetic spark, who have new and creative ideas that will change how things are done + In the market of ideas and technology, the top performers are at least 10x more valuable than the average performers—making hiring of utmost importance * Talented candidates can look ‘beyond the immediate moment‘ + “It’s very easy to optimize too locally…always try to be looking one level broader”– Tyler Cowen + Example: Ask them if Romeo & Juliet were really in love with each other? Or ask who was the best talent scout in Star Wars? Figure out one of the candidate’s interests and ask a question that explores their perception and thought-process rather than just knowledge. * Unique interview questions: + What tabs are currently open on your browser right now? Engaging this question will give you an idea of how they manage their ideas consumption. + Which conspiracy theory do you think is plausible? Regardless of the truth, it shows that the candidate is curious and capable of thinking outside the box. + How ambitious are you? It’s very hard to fake this answer. + How do you practice and improve? Very few people treat their chosen pursuit like that of an athlete or musician. Exceptional people constantly evaluate how their inputs affect their outputs, but few people do it in their professional work.

Read the full notes @ podcastnotes.org

Tyler Cowen is the Holbert L. Harris Chair of Economics at George Mason University, a columnist, podcaster and an author.

Finding and recruiting the best talent is perhaps the most important job that an organisation has. Skilful, enthusiastic, keen staff can make or break a business, so why is it that most companies are mostly useless when it comes to discovering talent?

Expect to learn whether population collapse is coming very soon, whether talent is innate or developed, why there is a crisis of talent when we have more people on earth than ever before, whether you should look at someone's parents before hiring them, the best questions to ask in an interview, what SpaceX's hiring strategy teaches us about thoroughness, how Tyler screens young staff for the most original thinkers and much more...

Sponsors:

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

Get 83% discount & 3 months free from Surfshark VPN at https://surfshark.deals/MODERNWISDOM (use code MODERNWISDOM)

Get 15% discount on Upgraded Formulas Test Kit at https://upgradedformulas.com/ (use code: MW15)

Get 20% discount on the highest quality CBD Products from Pure Sport at https://bit.ly/cbdwisdom (use code: MW20)

Extra Stuff:

Buy Talent - https://amzn.to/3t5cs5Z

Follow Tyler on Twitter - https://twitter.com/tylercowen

Check out Tyler's website - https://marginalrevolution.com/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Huberman Lab

Podcast Notes Key Takeaways * In many ways, grief is like a phantom limb – after amputation, you will feel like your limb is still there when it’s gone * Five stages of grief (non-linear & not everyone makes their way through all stages): (1) denial; (2) anger; (3) bargaining; (4) depression; (5) acceptance * People move through grief at different rates due to life circumstances, hormones, etc. * Grief is not just for people– you can be immensely attached & grieve a person, animal, or thing that is no longer in life for any reason (death, rehoming, lost object) * Grief is both a state of pain and a state of wanting which drives the activation state – we seek out how to resolve the pain * Once someone is gone, we’re put into an action state of looking for and seeking that person, expecting them to contact us or see them when we’d expect * All relationships are mapped through the brain and body through three dimensions: (1) space; (2) time; (3) closeness (emotional) * To get through grief, we have to remap our attachment– grief is the process of uncoupling and reordering our relationship from space, time, and closeness (e.g., not expecting to see them at a certain place or time) * Get close to and deliberately experience attachment to that person/object/animal – don’t distract yourself or focus on counterfactual thinking (i.e., “what ifs”) * As always, sleep is critical to regulating hormones, neuroplasticity, and setting yourself up for the healthiest overall autonomic state which will help you navigate grief (and life)

Read the full notes @ podcastnotes.org

This episode, I discuss grief and the challenges of processing losses of different kinds. I explain the biological mechanisms of grief, including how neural circuits for emotional and factual memory combine with those for love and attachment, to create feelings of absence and yearning. I discuss how grief is distinct from depression, yet why they can feel so similar. I also provide science-based tools to assist with the grieving process, including how to reframe and remap the relationship with those we have lost while still maintaining a strong emotional connection to them. I also explain the importance of having and building strong foundational psychological and biological states so that we can better cope with grief when it happens. Finally, I describe tools to adjust those states, including those for accessing sleep, managing stress and emotional swings. This episode is for those suffering from grief but also for everyone, given that we all experience grief at some point in our lives.

We recorded this episode before the recent mass shooting tragedies in the United States. While we hope the information in this episode will be of use to anyone suffering from grief of any kind and at any time, we are also careful to acknowledge that many people require additional support and resources. For that reason, we include mention of such resources and we generally hope people will access them if needed.

Thank you to our sponsors

Eight Sleep: https://www.eightsleep.com/huberman

InsideTracker: https://insidetracker.com/huberman

ROKA: https://www.roka.com/huberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Grief & Bereavement

(00:03:44) Eight Sleep, InsideTracker, ROKA

(00:08:35) Grief vs. Depression, Complicated Grief

(00:12:20) Stages of Grief, Individual Variation for Grieving

(00:16:05) Grief: Lack & Motivation, Dopamine

(00:23:15) Three Dimensions of Relationships

(00:29:52) Tool: Remapping Relationships

(00:37:15) Grief, Maintaining Emotional Closeness & Remapping

(00:44:40) Memories of Loved Ones & Remapping Attachments

(00:48:04) Yearning for Loved Ones: Memories vs. Reality, Episodic Memory

(00:51:40) Tools: Adaptively Processing Grief, Counterfactual Thinking, Phantom Limbs

(01:00:32) Tool: Remembering Emotional Connection & Processing Grief

(01:04:03) Memories, Hippocampal Trace Cells & Feeling An Absence

(01:10:14) Yearning & Oxytocin, Individualized Grief Cycles

(01:18:24) Tool: Complicated Grief & Adrenaline (Epinephrine)

(01:24:37) Sentimental Attachment to Objects

(01:26:13) Why do Some People Grieve More Quickly? Individual Attachment Capacity

(01:29:42) “Vagal Tone,” Heart Rate, Breathwork & Grief Recovery

(01:42:32) Complicated Grief & Cortisol Patterns

(01:48:50) Tool: Improving Sleep & Grieving

(01:54:28) Tools: Grief Processing & Adaptive Recovery

(02:03:36) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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The Kevin Bass Show ✓

Claim

Podcast Notes Key Takeaways * Sauna use just 2x per week will kill off 75% of sperm and reduce motility in the remaining sperms by almost 1/3 * Normal sperm function and count may take 6 months post-last sauna exposure to be restored * Limitations: we don’t know the effects on men with reduced sperm function/count at baseline; it’s unclear whether effects would be different with more sauna use; the study was done on older men so we don’t know about effects on younger men * Sauna use has been all the rage lately, make sure you’re planning use in accordance with your family planning

Read the full notes @ podcastnotes.org

In this podcast, I discuss a paper that shows profound reductions in sperm concentration (nearly 75%), total sperm count (2/3), and sperm motility (half) after just two 15-minute sauna sessions per week for three months (PMID 23411620). These changes were not reversed after three months cessation of sauna use; a full six months were required for these changes to reverse. It is unknown how the sauna may impact spermatogenesis among those who already have impaired testicular function or during development.

It is important to fully explain the risks and harms of interventions that are massively hyped on social media. This podcast offers itself as a corrective to overhyping by the most popular and well-known American health influencers.

===

Like, comment, subscribe.

For more, find me at:

PODCAST The Kevin Bass Show

YOUTUBE https://www.youtube.com/user/kbassphiladelphia

WEBSITE http://thedietwars.com

TWITTER https://twitter.com/kevinnbass/

https://twitter.com/healthmisinfo/

INSTAGRAM https://instagram.com/kevinnbass/

TIKTOK https://tiktok.com/@kevinnbass

And above all, please donate to support what I do:

PATREON https://patreon.com/kevinnbass/

DONATE https://thedietwars.com/support-me/

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My First Million

Podcast Notes Intro * Everyone sucks the first time they manage people. Check out Shaan’s unorthodox management techniques to learn how to suck less and get more results. * Host: Shaan Puri (@ShaanVP), no Sam (@thesamparr) on this episode!

Read the full notes @ podcastnotes.org

Shaan Puri (@ShaanVP) shares his tried and true unconventional management tips that you won't learn in business school.

Links:

Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(02:40) - Tip 1 Dr. House

(05:25) - Tip 2 The Holiday

(08:30) - Tip 3 Misery Love Company

(09:00) - Tip 4 Hired Too Many

(12:45) - Tip 5 Super Power

(17:40) - Tip 6 Tesla Master Plan

(20:15) - Tip 7 Calendar Audit

(21:10) - Tip 8 Peer Groups

(22:00) - Tip 9 Kickoff Document

Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more.

Additional episodes you might enjoy:

• #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits

• #209 Gary Vaynerchuk - Why NFTS Are the Future

• #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

• #218 - Why You Should Take a Think Week Like Bill Gates

• Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More

• How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

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Infinite Loops

Podcast Notes Key Takeaways * Check out Infinite Loops Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Ben Hunt is the creator and primary author of Epsilon Theory, and co-founder and CIO at Second Foundation Partners.
Epsilon Theory is a newsletter that examines markets through the lenses of game theory and history. Over 100,000 professional investors and allocators across 180 countries read Epsilon Theory for its fresh perspective and novel insights into market dynamics.
You can follow Ben on Twitter at https://twitter.com/EpsilonTheory and read Epsilon Theory here: https://www.epsilontheory.com/

Show Notes:

Neurolinguistic hard reset
Ben’s days at Harvard
Why Klaus Schwab is a raccoon
Human beings are social animals
How language impacts and limits us
The cost of the Metaverse
How the nudging state is rewiring us
Does narrative follow price, or is it the inverse?
Traders respond to stories everyday
How technology can fight the nudging state.
NOAH: An ark of stories on the blockchain

Books Mentioned:

The WEIRDest People in the World; by Joseph Henrich
How the Irish Saved Civilization; by Thomas Cahill

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MInd Pump

Podcast Notes Key Takeaways * TheZ Press is the best shoulder exercise you can do + Muscles are weakest at their end range, the Z Press attacks those areas and will help you unlock new gains from traditional exercises * Tips for cutting: + Instead of more weight, change up your reps + Perfect your form and tempo + Totally change up your program when you switch from bulking to cutting – this creates new stimuli and your psyche will be more in check * How to target lacking lower muscle groups: + Focus on mobility + Start every workout with legs– try isolation exercises before your compound lifts * Back pain can come from a variety of sources: ankle mobility, foot stability, hip strength, core weakness, or upper back instability + The Maps Prime program helps pinpoint your pain source and how to improve * Continue reading for more in-depth analysis of each of these tips and other interesting topics

Read the full notes @ podcastnotes.org

In this episode of Quah (Q & A), Sal, Adam & Justin coach three Pump Heads via Zoom.

Mind Pump Fit Tip: One of the BEST exercises for full, round delts is the Z-Press! (2:29)
Mind Pump’s breakfast staples. (11:24)
Caffeine is a gnarly drug! (17:32)
Mind Pump Investments: The tumbling Stock Market and Coinbase plummeting. (21:00)
The tragedy surrounding the baby formula shortage. (23:04)
If you lead a healthy life, it’s less expensive. (26:24)
AirPods are a hell of a product! (27:58)
A new study reveals why teenagers tune out their parents’ voices. (31:18)
Subscribe to Mind Pump Clips on YouTube! (35:34)
Nike blasts StockX for selling counterfeit shoes. (36:35)
How your bowel movements tell the story of your health. (39:20)
The many benefits of alpha-lipoic acid on your body's cells. (44:39)
ListenerLive question #1 - Should I be aiming for progressive overload while I’m in a calorie deficit? (49:19)
ListenerLive question #2 - Do you have any advice on how to get my leg strength and mass to catch up to my upper body? (1:00:11)
ListenerLive question #3 - Where should I start in fixing my squat so I'm pain-free? (1:13:05)

Related Links/Products Mentioned

Ask a question to Mind Pump, live! Email: live@mindpumpmedia.com
Visit Magic Spoon for an exclusive offer for Mind Pump listeners!
Visit LivON Labs for an exclusive offer for Mind Pump listeners!
May Promotion: MAPS Starter Bundle and MAPS Spilt 50% off! Promo code MAYSPECIAL at checkout
Z Press to take Your Shoulder Development to the Next Level – Mind Pump TV
Coinbase reels as cryptocurrency prices slump
Why baby formula is in short supply — and who is most at risk
Consumer debt totals $15.6 trillion in 2021, a record-breaking increase
AirPods is a hell of a product… wonder what the earnings/margins would look like!
New Study Reveals The Reason Teens Seem to Tune Out Their Mom's Voice
Mind Pump Clips - YouTube
Nike Blasts StockX for Selling Counterfeit Shoes | HYPEBEAST
‘Smart toilet’ monitors for signs of disease
This Smart Toilet Can Read Your Anus Like a Fingerprint
Visit ZBiotics for an exclusive offer for Mind Pump listeners!
Mind Pump #1630: Ten Ways To Break Through A Plateau
MAPS Symmetry
MAPS Fitness Anabolic
Mind Pump #1745: How To Pack On Muscle To Your Lagging/Stubborn Body Parts
Mind Pump #1337: Five Reasons Why Your Legs Won’t Grow
MAPS Aesthetic
The Only Way You Should Be Doing Bulgarian Split Squats! (BUTT GROWTH) - Mind Pump TV
How To Do The Sled Push The RIGHT Way! (AVOID MISTAKES!) - Mind Pump TV
MAPS Powerlift
MAPS Fitness Performance
Fix Your Back Pain – Mind Pump Blog
Prime Bundle | MAPS Fitness Products
MAPS Prime Webinar
MAPS Prime Pro Webinar
Mind Pump Podcast – YouTube
Mind Pump Free Resources

Featured Guest/People Mentioned

Christopher M. Naghibi (@chrisnaghibi) Instagram
Jason Calacanis (@JasonCalacanis) Twitter
Dr. Stephen Cabral (@stephencabral) Instagram
Bret Contreras PhD (@bretcontreras1) Instagram

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My First Million

Podcast Notes Key Takeaways * You don’t have to know exactly why your business works until well after it’s launched + “You can say ‘I don’t know’ or ‘the same as everyone else’ to all questions as long as you have that one thing”– Shaan Puri + Your business is going to change and evolve anyway, so don’t let anything prevent you from getting it started in the first place * “I don’t know anything about deodorant, but in six months, I’m going to know everything there is to know”– Moiz Ali + Nobody is an expert when they start! Apply this to any idea. * Every Direct to Consumer (D2C) business should know its customer acquisition cost (CAC) + And then, constantly improve on it! “If you’re completely divorced from customer feedback, you’re setting yourself up for disaster” – Moiz Ali * Ask more questions like this: How do you think about (blank)? + Responses will be more honest and open-ended rather than numeric and analytical * Feel good unconditionally, force the good out of the average + Think about the DMV. If you want five-star service, be a five-star customer.

Read the full notes @ podcastnotes.org

Shaan Puri (@ShaanVP) sits down with entrepreneur and former CEO of Native, Moiz Ali (@MoizAli), to talk about how to find the competitive advantage for your business, three common mistakes DTC brands make, investment tips and more.

Links:

Native
Haldirams
Manscaped
Brumate
Moiz's sell sheet tweet
Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel.
Want more insights like MFM? Check out Shaan's newsletter.

Show Notes:

(04:20) - Starting Native in secret

(13:50) - Figuring out your competitive advantage

(24:00) - Common mistakes in DTC brands

(35:00) - Stock tips on D2C tech companies

(38:10) - Real estate investments

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Huberman Lab

Podcast Notes Key Takeaways * Three essentials to improve learning, focus, and retention: exercise, meditation, sleep * Four things make something memorable: (1) novelty; (2) repetition; (3) association; (4) emotional resonance (we remember the happiest & saddest moments) * If you have trouble incorporating a cold protocol, try Dr. Suzuki’s method: blast yourself with cold water at the end of your warm shower * Exercise can allow you to focus longer and deeper, reduce stress and anxiety, and enhance mood (among many other benefits) * Don’t overcomplicate exercise! Shoot for getting your heart rate up 30-45 minutes per day in any way you like * “Our brain is an organ that requires a signal to maintain its function.” – Dr. Andrew Huberman * Our brain responds to increases in exercise: the more days of exercise, the better our mood and the greater our hippocampal memory becomes * Even on limited time, consider exercising or stretching for even 5 minutes to maintain the habit * Intimidated by an hour of meditation? Just 12 minutes per day can enhance cognitive performance, reduce stress, and improve mood * “The ability to focus and attend is the distinguishing feature between those that will succeed in any endeavor and those that won’t.” – Dr. Andrew Huberman

Read the full notes @ podcastnotes.org

My guest is Dr. Wendy Suzuki, Ph.D., Professor of Neural Science and Psychology and (soon) Dean of New York University, whose research focuses on memory, attention, brain plasticity and simple, daily habits that can be leveraged to improve learning, focus, memory and cognitive ability. We discuss the role of cardiovascular exercise, weight training, deliberate cold exposure, meditation, verbal affirmations, sleep, and other behavioral practices for enhancing learning, mood and stress management, and increasing attention span. Dr. Suzuki shares the mechanisms by which these practices change our brain in order to improve cognitive function fast and reduce age-related cognitive decline.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

InsideTracker: https://insidetracker.com/huberman

Blinkist: https://www.blinkist.com/huberman

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Wendy Suzuki, Learning & Memory

(00:02:50) AG1 (Athletic Greens), InsideTracker, Blinkist

(00:07:27) How Memories Form

(00:10:14) Hippocampus: Memory, Association & Imagination

(00:16:20) Encoding Long-Term Memory

(00:18:48) One-Trial Memory

(00:21:56) Tool: Foundational Habits to Enhance Brain Performance

(00:30:39) Exercise & Improved Memory, Making a “Big, Fat, Fluffy Hippocampus”

(00:39:35) Cardiovascular Exercise, BDNF (Brain-Derived Neurotrophic Factor)

(00:48:48) Neurogenesis (New Neuron Production) in Adults

(00:51:50) Effects of Exercise on Memory

(00:56:31) Tool: Timing Daily Exercise, Cortisol

(01:00:02) Age-Related Memory Loss, Daily Exercise

(01:05:33) Tool: Exercise Protocol for Improving Cognition

(01:12:17) Anticipating Exercise, Daily Habits & Behaviors

(01:17:09) “Every Drop of Sweat Counts” – Exercise & Cognitive Function

(01:20:58) Positive Affirmations & Mood

(01:27:28) Meditation & Cognitive Performance

(01:32:27) How Meditation Works, Focusing on the Present

(01:37:14) Tool: Strategies to Increase Attention

(01:42:50) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

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Econtalk

What's the single best thing happening in technology right now? According to entrepreneur and venture capitalist Marc Andreessen, it's the ability to live in rural Wisconsin but still earn a Silicon Valley salary. Andreessen also explains to EconTalk host Russ Roberts why software is still eating the world, why he's an optimist, and why he's still bullish on Bitcoin and the blockchain.

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Huberman Lab

Podcast Notes Key Takeaways * New memories are formed through repetition or immensely positive/negative events * Emotionality and emotion experienced after an event dictates whether you will learn it quickly * Memories are formed because of a neurochemical state (release of adrenaline, cortisol, epinephrine, norepinephrine) that takes place following an emotion – not because something evokes emotion itself * Timing of caffeine for memory and learning enhancement matters: consume caffeine immediately after or 5-15 minutes after repetition * To optimize learning: immediately after learning, put the body into a heightened state of emotionality and alertness (e.g., caffeine, cold exposure); hours later, a nap (28-90 minutes) or non-sleep deep rest is critical for learning and memory * Anything that increases adrenaline will increase learning and memory and reduce the number of repetitions required to learn something (regardless of whether there’s emotion attached) * Anything that reduces epinephrine and adrenaline will impair learning * Chronic stress and elevation of epinephrine are detrimental to memory and learning (among many other things) * Physical movement can enhance cognitive ability and ability to learn new skills – shoot for 180-200 minutes of zone 2 cardio per week and a few sessions of load-bearing exercise per week * Taking a mental snapshot (blinking and imagining you are taking a photo of something) actually stamps down visual memory almost as much as taking an actual photo * Meditation can improve attention, memory, mood, and emotion regulation but timing matters! If you meditate too late, it may actually hinder sleep because you are in a calm but highly attentional state * As always, start with behavioral tools before exploring pharmacology

Read the full notes @ podcastnotes.org

This episode I explain the mechanisms by which different types of memories are established in our brain and how to leverage the amount and timing of key neurochemicals and hormones, such as adrenaline (aka epinephrine) and cortisol, to improve your learning and memory abilities. I describe multiple science-based protocols to do this, including repetition, caffeine, emotional states, deliberate cold exposure, sleep, meditation, and the role of vision, including taking “mental snapshots.” I also describe how exercise and an associated hormone, osteocalcin, can improve cognitive ability and memory formation. I also describe unique aspects and forms of memory such as photographic memory, extreme facial recognition (aka super recognition), and the phenomenon known as déjà vu.

Thank you to our sponsors

Eight Sleep: https://www.eightsleep.com/huberman

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Memory, Improving Memory

(00:02:45) Eight Sleep, Thesis, InsideTracker

(00:07:54) Sensory Stimuli, Nervous System & Encoding Memory

(00:11:12) Context & Memory Formation

(00:13:46) Tool: Repetition, Improving Learning & Memory

(00:17:11) Co-Activation and intensity Neuron Activation

(00:20:50) Different Types of Memory

(00:25:40) Memory Formation in the Brain, Hippocampus

(00:28:00) Hippocampus, Role in Memory & Learning, Explicit vs. Implicit Memory

(00:31:49) Emotion & Memory Enhancement

(00:36:44) Tool: Emotion Saliency & Improved Memory

(00:41:42) Conditioned-Placed Avoidance/Preference, Adrenaline

(00:47:14) Adrenaline & Cortisol

(00:49:35) Accelerating the Repetition Curve & Adrenaline

(00:53:03) Tool: Enhancing Learning & Memory - Caffeine, Alpha-GPC & Stimulant Timing

(01:00:50) Tool: Enhancing Learning & Memory - Sleep, Non-Sleep Deep Rest (NSDR)

(01:04:48) Tool: Enhancing Learning & Memory - Deliberate Cold Exposure, Adrenaline

(01:08:42) Timing of Adrenaline Release & Memory Formation

(01:12:36) Chronically High Adrenaline & Cortisol, Impact on Learning & Memory

(01:15:12) Adrenaline Linked with Learning: Not a New Principle

(01:17:25) Amygdala, Adrenaline & Memory Formation, Generalization of Memories

(01:22:20) Tool: Cardiovascular Exercise & Neurogenesis

(01:27:00) Cardiovascular Exercise, Osteocalcin & Improved Hippocampal Function

(01:29:59) Load-Bearing Exercise, Osteocalcin & Cognitive Ability

(01:34:41) Tool: Timing of Exercise, Learning & Memory Enhancement

(01:37:29) Photographic Memory

(01:38:49) “Super Recognizers,” Facial Recognition

(01:41:46) Tool: Mental Snapshots, Photographs & Memory Enhancement

(01:49:12) Déjà Vu

(01:53:24) Tool: Meditation, Daily Timing of Meditation

(02:02:21) How to Enhance Memory

(02:05:51) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

View Details

Infinite Loops

Podcast Notes Key Takeaways * Check out Infinite Loops Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Nick Maggiulli is a financial educator, author of the blog “Of Dollars and Data”, and the newly released book “Just Keep Buying: Proven Ways To Save Money And Build Your Wealth.”

In this episode, we talk with Nick about the robust empirical research that has gone behind the insights and ideas presented in his new book!

You can follow Nick on Twitter at https://twitter.com/dollarsanddata and buy his book at https://ofdollarsanddata.com/justkeepbuying/

Show Notes:

Coming up with title of the book
The save-invest continuum
Is buying a house a good investment?
Debt: Good or bad?
On being shaped by our experiences
One path the wealth creation?
2020 vs 2021 as an investment year
Handling emotions during a bear market
Importance of diversification
The ideal asset allocation
The Great Reshuffle
The argument against stock picking
Negative yield bonds
Lump sum vs. DCA
Index investors or momentum investors
Life as a growth, and value stock

Books Mentioned:

Just Keep Buying; by Nick Magguilli
Security Analysis; Benjamin Graham
The Intelligent Investor; Benjamin Graham
Influence; by Robert Cialdini

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Jack Murphy Live

Podcast Notes Key Takeaways * Desire is why people want what they want + Mimetic desire: relying on external references “to show us what is wantable” + We are usually unaware of how much of our self-proclaimed individualism is sourced from thoughts and desires that are not our own * We often fight because of our sameness, not because of our differences + Conflict emerges when differences are eliminated; everyone begins to fight over the same things * Mimetic crisis: occurs when there is a loss of difference + When friend/enemy distinctions collapse, people try really hard to create differences + Scapegoats are the reintroduction of difference, which inherently is the reintroduction of peace (as counterintuitive that sounds) + “Humans have always relied on violence to drive out violence throughout human history” – Luke Burgis * The problem with data: “Data at its best can only represent the state of things right now…it just captures what people presently want” – Luke Burgis + Truly good ideas aren’t shaped by desire; good ideas shape desire * An enjoyable life comes down to ordering your desires well + You must know the difference between your personal desires and the desires that simply have a great presentation + Prioritize your “thick” desires (continue reading for more info) * We should do away with the façade of desire and be honest with ourselves about what we want. Living out a meaningful life is not selfish. + We are living in a world where it’s harder than ever to express your true desires + Listen to yourself more often

Read the full notes @ podcastnotes.org

Jack Murphy sits down with Luke Burgis, author of "Wanting: The Power of Mimetic Desire in Everyday Life" - an insightful book that draws on the work of French polymath René Girard to bring this hidden force to light and reveals how it shapes our lives and societies.

Why do you want what you want?

And how do we influence what other's want?

Once you understand the power of memetic contagion, you'll see it everywhere.

"A groundbreaking exploration of why we want what we want, and a toolkit for freeing ourselves from chasing unfulfilling desires. Gravity affects every aspect of our physical being, but there’s a psychological force just as powerful―yet almost nobody has heard of it. It’s responsible for bringing groups of people together and pulling them apart, making certain goals attractive to some and not to others, and fueling cycles of anxiety and conflict. In Wanting, Luke Burgis draws on the work of French polymath René Girard to bring this hidden force to light and reveals how it shapes our lives and societies. According to Girard, humans don’t desire anything independently. Human desire is mimetic―we imitate what other people want. This affects the way we choose partners, friends, careers, clothes, and vacation destinations. Mimetic desire is responsible for the formation of our very identities. It explains the enduring relevancy of Shakespeare’s plays, why Peter Thiel decided to be the first investor in Facebook, and why our world is growing more divided as it becomes more connected. Wanting also shows that conflict does not arise because of our differences―it comes from our sameness. Because we learn to want what other people want, we often end up competing for the same things. Ignoring our large similarities, we cling to our perceived differences."

https://www.amazon.com/Wanting-Power-Mimetic-Desire-Everyday/dp/1250262488

Jack Murphy's Book, "Democrat To Deplorable," Now Available On Audiobook: https://adbl.co/3qXvlEY

Liminal Order: https://www.liminal-order.com

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Wanting: The Power of Mimetic Desire in Everyday Life

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MInd Pump

Podcast Notes Key Takeaways * Always eat your proteins first + You will naturally eat fewer calories; protein is the most satiating macronutrient * What to do when a muscle group is lagging: + Don’t add more sets to your routine; instead, redistribute your sets to accommodate + Bring the muscle group to the front of your workout—you get the most muscle gain out of the workouts you do first * “The worst myths in the health and fitness space have some truth in them”– Mind Pump + Muscle Confusion: a delicate balance between trying to master a lift and creating enough variation to avoid plateauing * Failure training provides short term results that fade quickly + “For the average lifter, avoiding it is probably a good idea” – Mind Pump + The body tax and risk for injury simply aren’t worth the benefits

Read the full notes @ podcastnotes.org

In this episode of Quah (Q & A), Sal, Adam & Justin answer Pump Head questions about growing stubborn biceps, whether changing phases is effective because of “muscle confusion,” if it is ok to train to failure if only focusing on a muscle group once a week, and whether bodybuilding is healthy.

Mind Pump Fit Tip: Here’s a simple tip that will get you leaner and healthier. EAT PROTEIN FIRST! (2:29)
Crypto ads are EVERYWHERE! (9:18)
People are the currency. (13:21)
Why the Supreme Court leak is very scary. (17:28)
Should there be warning labels on sugary drinks? (23:44)
Caldera Labs is clinically proven to work on ALL skin types! (31:51)
Dad life updates with Adam, Justin, and Sal. (38:26)
Vuori is your Mother’s Day one-stop shop. (41:42)
Will movie theaters ever go away? (45:54)
Quah question #1 - Incredibly stubborn bicep and tricep growth despite all other muscle groups improving. Should I target volume or intensity, and are giant sets counterproductive or overworking? (58:42)
Quah question #2 - Does the effectiveness of changing phases for hypotrophy say anything about the truth behind “muscle confusion?” (1:07:10)
Quah question #3 - Is it ok to train to failure if I’m only focusing on a muscle group once a week? (1:15:08)
Quah question #4 - Is bodybuilding healthy? (1:21:10)

Related Links/Products Mentioned

Visit Caldera Lab for an exclusive offer for Mind Pump listeners! Code MINDPUMP at checkout
Visit Vuori Clothing for an exclusive offer for Mind Pump listeners!
May Promotion: MAPS Starter Bundle and MAPS Spilt 50% off! Promo code MAYSPECIAL at checkout
Visit NutriSense for the exclusive offer for Mind Pump listeners! Promo code “MINDPUMP” at checkout
Why do we Need Protein? - Mind Pump Blog
Crypto Advertisements Are Everywhere: The Consumer Isn't A Moron
Warren Buffet Just Took Another Shot at Bitcoin. What Does He Know That You Don't?
Researchers find Amazon uses Alexa voice data to target you with ads
YouTube Algorithms Don't Turn Unsuspecting Masses Into Extremists, New Study Suggests
Supreme Court says leaked abortion draft is authentic; Roberts orders investigation into leak
Warning Labels on Sugary Drinks: Do They Work?
Visit Oli Pop for an exclusive offer for Mind Pump listeners! Promo code MINDPUMP at checkout for 15% off your first order
Caldera Lab clinical trial
Preference for watching a movie for the first time at a theater instead of via a streaming service in the United States from November 2018 to June 2020
Visit MASSZYMES by biOptimizers for an exclusive offer for Mind Pump listeners! Promo code MINDPUMP10 at checkout
Mind Pump #1417: How To Get Stubborn Arms To Grow
Mind Pump #1745: How To Pack On Muscle To Your Lagging/Stubborn Body Parts
How Phasing Your Workouts Leads to Consistent Plateau Free Workouts – Mind Pump Blog
3 Tips for Better Muscle Growth – Mind Pump Blog
Mind Pump #1542: How Bodybuilders Ruined Weight Lifting For Everyone
Mind Pump Podcast – YouTube
Mind Pump Free Resources

People Mentioned

Jeremy L. Buendia (@jeremy_buendia) Instagram
Chris Bumstead (@cbum) Instagram

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Huberman Lab

Podcast Notes Key Takeaways * Neural circuits (not individual brain areas) trigger aggression * Aggression is not a switch, it’s a process with a beginning, middle, and end * Aggression actually hinges on the hormone estrogen * Testosterone in and of itself does not trigger aggression – testosterone aromatized into estrogen within the brain and binding to estrogen receptors in area of the brain that leads to aggression * Estrogen triggers aggression in brain and testosterone increases the pressure toward an aggressive episode * Recipe for aggression & reactivity: increased cortisol, reduced serotonin, short days * Self-regulation is a key component of whether someone will engage in aggressive behavior * Tools to reduce aggressive tendencies and impulsivity: pay attention to how daylight changes makes you feel, supplement with omega-3, supplement with ashwagandha in 2 week on/2week off cycles, get sunlight early in the day, try a hot bath or sauna, avoid beverages that contain both alcohol and caffeine

Read the full notes @ podcastnotes.org

This episode I describe the neural mechanisms that activate and control aggressive states and beahviors and the role of hormones—estrogen and testosterone—in mediating violent and and/or competive aggression. I also describe tools that can be used to modulate the factors that have been shown to ‘prime’ an individual for aggression, including sunlight, estrogen sensitivity, competition within social settings, and overall stress levels, and the hormone cortisol. I discuss how substances such as caffeine and alcohol can impact impulsive behaviors, and how nutrition and supplementation can be used to regulate mood and aggression.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

ROKA: https://www.roka.com -- code: huberman

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Our Patreon page

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Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Aggression, Types of Aggression

(00:03:33) AG1 (Athletic Greens), ROKA, Helix Sleep

(00:08:29) Neural Circuits for Aggression, “Hydraulic Pressure Model”

(00:15:50) Brain Regions Controlling Aggression, Ventromedial Hypothalamus (VMH)

(00:22:14) Psychiatric Disorders & Aggression

(00:23:36) Stimulation of the VMH, Estrogen Receptors & Aggression

(00:31:57) Neural Circuits Mediating Physical Acts of Aggression, Biting

(0:35:56) Testosterone & Competitiveness/Estrogen & Aggression

(00:43:00) Sunlight, Melatonin & Aggression

(00:45:46) Cortisol, Serotonin & Aggressive Behaviors

(00:51:56) Tool: Omega-3 Supplementation & Mood

(00:54:18) Tool: Sunlight, Sauna & Cortisol Reduction

(00:55:54) Tool: Ashwagandha & Cortisol Reduction

(00:57:06) Tool: Seasonality/Sunlight, Genetic Variation in Estrogen Sensitivity

(01:00:37) Testosterone & Aggression, Competitive Work Environments

(01:05:07) Testosterone, Amygdala, Challenge & Effort

(01:09:27) Caffeine, Alcohol & Impulsivity

(01:13:15) Tool: Caffeinated Alcohol Beverages, Impulsivity & Aggression

(01:17:18) Tool: ADHD, Acetyl-L Carnitine & Aggressive Behavior

(01:24:10) Factors Affecting the “Hydraulic Pressure Model” of Aggression

(01:25:44) Book by Dr. David Anderson, Aggression & Social Relationships

(01:27:35) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Twenty Minute VC

Podcast Notes Key Takeaways * Don’t shield your kids from the world. Kids understand fairness and inequity; they will be better off having exposure to varying perspectives and experiences. + Due to overexposure to monoculture and struggle-free lifestyle, “we have a surplus of assholes coming down the pike right now” – Chris Sacca * Parenting forces work/life balance and efficiency on you + It taught Ann Wojcicki how to delegate; she realized she didn’t need to be a part of every meeting + In the words of Deena Shakir, kids give you “ruthless prioritization” * Kids value presence over everything. + Presence isn’t physical, it’s mental. Presence is your attention. * “Once you have children, the art of being a good parent and the art of being a good leader are the same”– Ian Siegel + Patience & Listening: You must be able to suppress your first reaction and think about the outcome you want to create * You can learn a lot about negotiation by becoming a parent + Deena Shakir actually recommendsHow to Talk So Little Kids Will Listen by Joanna Faber and Julie King as a business book more so than a parenting book * Micromanagement is a poor strategy in both leadership and parenting. You want to model behaviors rather than enforce behaviors.

Read the full notes @ podcastnotes.org

  Chris Sacca is the Founder and Chairman @ Lowercase Capital, one of the best performing funds in the history of venture capital with a portfolio including Uber, Stripe, Twitter, Instagram, Twilio, Docker and many more.        * Why does Chris believe we have bred a generation of asshole kids?

What is the right way to negotiate with children? How has that impacted how he manages his team?

Anne Wojcicki is the Founder & CEO @ 23andMe, offering DNA testing with the most comprehensive ancestry breakdown, personalized health insights, and more.

How did having kids change Anne's approach to time allocation and risk?

Harley Finkelstein is the President of Shopify. Over the last 12 years, Harley has partnered with Tobi to the tune of building Shopify’s revenue to over $4.6BN in 2021 and the team to over 10,000 employees.

Does Harley believe he has always been a good father?
What changes has Harley made to be more present and there for his children?
Why does Harley advise couples therapy as early in a relationship as possible?

Deena Shakir is a Partner at Lux Capital, one of the leading firms investing in emerging science and technology ventures at the outermost edges of what is possible.

What specific negotiation tactics from parenting can be applied to business?
How can a parent show their children they listen, they understand and are there for them?
Why does Deena believe children make you more productive and more efficient?

Eric Liaw is a General Partner @ IVP, one of the leading later-stage venture capital and growth equity firms of the last decade with $8.7 billion of committed capital and a 40-year IRR of 43.1%.

What have been the biggest challenges for Eric of managing family and work?
What have been some of Eric's biggest lessons in terms of how he communicates about his work to his family?

Scott Dietzen is Vice Chairman of the Board of Pure Storage and served as the Company’s CEO from 2010 to 2017. Under his leadership, Pure grew to thousands of employees and
completed an IPO in 2015.

What can parents learn from nature programs?
What core elements of parenting are directly transferrable to management?

How to Talk so Little Kids Will Listen: A Survival Guide to Life with Children Ages 2-7 (The How To Talk Series)

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * Spend as much time as possible working on dynamic stability, static stability, strength training * Training “zones” are really a function of the underlying system you are referring to whether it’s heart rate based or power based * Most people spend too much time in zone 5 and not enough in zone 2 * The limits of human performance for truly going “all out” is about 10 seconds – look at the difference between Olympians in the 100m versus 200m * Training for longevity: work backwards from 100 years old and think about what you physically have to do to be happy with your life (e.g., play with grandkids, get up from the floor, garden, bike ride, etc.) * There is an increase in mortality with reduction in grip strength and loss of quad muscle * Life generally takes place in zone 2 and zone 5 so this is what we want to train * “Stability is the cornerstone upon which you do everything” – Dr. Peter Attia * Peter’s current exercise routine: M-W-F lift (split upper and lower body); Tu-Th-Sat zone 2 cardio; Sun zone 2 cardio then zone 5 cardio

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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In this special episode of The Drive, we have pulled together a variety of clips from previous podcasts about exercise to help listeners understand this topic more deeply, as well as to identify previous episodes which may be of interest. In this episode, Peter discusses his framework for exercise, what he’s really optimizing for, and how to train today to be prepared for a good life at age 100. He describes the importance of strength and stability, and why deadlifting is an important tool to consider for longevity. Additionally, he details why training in zone 2 and zone 5 is important, gives a primer on VO2 max, and describes the most effective ways to engage in those types of exercise. Finally, Peter reveals his current exercise routine.

We discuss:

What is Peter optimizing for with his exercise? [3:00];
Preparing for a good life at age 100: Training for the “Centenarian Olympics” [6:00];
The importance of preserving strength and muscle mass as we age [21:45];
The value of deadlifts for stability and longevity when done properly [27:30];
The importance of zone 2 aerobic training [35:45];
The most effective ways to engage in zone 2 exercise [40:00];
Zone 5 training and VO2 max [44:15];
A primer on VO2 max [52:00];
Stability—the cornerstone upon which all exercise and movement relies [1:03:00];
Peter’s current exercise routine [1:07:45];
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * Check out Lex Fridman Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Grimes is a musician, artist, singer, songwriter, producer, and director. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Novo: https://novo.co/lex – Lambda: https://lambdalabs.com/lex – Public Goods: https://publicgoods.com/lex and use code LEX to get $15 off – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Grimes’s Twitter: https://twitter.com/Grimezsz Grimes’s Instagram: https://www.instagram.com/grimes PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon:

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * Big reasons weight loss efforts might be failing: (1) Your wearable is probably not accurately tracking the actual calories burned during exercise; (2) People notoriously underreport energy/calorie intake (not intentionally, we often skip the handful of nuts or berries, but it all adds up); (3) Food labels are allowed up to 20% error * A calorie is a calorie, it’s a scientific measure of energy – but all sources of calories are not created equal * Peter’s rule of thumb: never do two bad things back to back – if you miss exercise today, be sure to exercise tomorrow; if you eat a cheat meal, make your next meal better * If you want to lose weight specifically, you will need to do some form of restriction on time or calories – could be calories, fat, carb, unprocessed food, fasting, etc. * The best diet is the one you can stick to! A lot of weight loss is really reprogramming habits and behaviors, more than any specific dietary dogma * You need to exercise! If you are focusing on cutting carbs and food restrictions, you are stepping over dollars to pick up pennies * Protein and calories are the most important things to consider in your diet – how you distribute carbohydrates and fat should be based on what you can adhere to and tolerate * Work your muscles to the full range of motion to maximize hypertrophy * Training frequency is more of a tool to distribute volume than it is a hypertrophy stimulus * Supplementing for hypertrophy training: whey, creatine monohydrate, maybe citrulline – you can skip BCAAs as long as you’re getting high-quality protein in your diet * Protein powder red flags: (1) Stay away from companies pitching “proprietary blends”; (2) Make sure brand isn’t nitrogen spiking (don’t want glycine on the label); (3) Watch out for unrealistic claims or “most anabolic” type marketing

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

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Sign Up to Receive Peter’s Weekly Newsletter

Layne Norton holds a Ph.D. in nutritional sciences and is a physique coach, natural bodybuilder, and previous guest on The Drive. In the first half of this episode, Layne dives deep into the topic of energy balance, including the role that macronutrients and calories play in weight loss. He describes how many people struggle with tracking food and calories on their own across a variety of diets and how all of this can impact nutritional habits and behaviors. In the second half of the episode, Layne discusses the importance of protein and weightlifting for improving one’s body composition and increasing muscle mass. He explains how he would prescribe different training and nutrition programs for two hypothetical clients—a 50-year-old female who is entering menopause and wants to improve her health, and a 40-to-50-year-old male who wants to maximize muscle mass. Additionally, Layne discusses a number of supplements that could potentially benefit a training program including whey protein, branch chain amino acids, creatine, nitric oxide boosters, and more.

We discuss:

Defining energy balance and the role of calories [2:30];
Defining a calorie, whether they are all created equal, and how much energy you can extract from the food you eat [8:00];
Factors influencing total daily energy expenditure [12:15]:
The challenge of tracking energy expenditure accurately, and the thermic effect of different macronutrients [23:30];
Challenges of sustained weight loss: metabolic adaptation, set points, and more [34:45];
Weight loss strategies: tracking calories, cheat meals, snacks, fasting, exercise, and more [40:45];
Sitting in discomfort, focusing on habits, and other lessons Layne learned as a natural bodybuilder [52:15];
Commonalities in people who maintain long-term weight-loss [1:01:15];
Does a ketogenic diet result in greater energy expenditure? [1:03:15];
The metabolic benefits of exercise, muscle mass, and protein intake [1:15:00];
The impact of lean muscle and strength on lifespan and healthspan [1:20:00];
Hypothetical case study #1: Training program for 50-year-old female [1:27:45];
Muscle protein synthesis in a trained athlete vs. untrained individual following a resistance training program [1:31:30];
Protein and amino acids needed to build and maintain muscle mass [1:37:15];
Nutrition plan for the hypothetical 50-year-old woman starting to build lean muscle [1:42:45];
Dispelling myths that excess protein intake increases cancer risk through elevations in mTOR and IGF [1:55:30];
Hypothetical case study #2: Training program for a 50-year-old, trained male wanting to increase muscle mass [2:04:00];
Maximizing hypertrophy while minimizing fatigue—is it necessary to train to muscular failure? [2:11:30];
Ideal sets and reps for the hypothetical 50-year-old male interested in hypertrophy [2:16:15];
Maximizing hypertrophy by working a muscle at a long muscle length [2:22:15];
Recommended lower body exercise routines and tips about training frequency [2:24:00];
Nutrition plan for the hypothetical 50-year old male wanting to add muscle [2:29:00];
Cycling weight gain and weight loss when building lean muscle mass, and expectations for progress over time [2:33:30];
Supplements to aid in hypertrophy training [2:38:30];
More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

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Modern Wisdom

Podcast Notes Key Takeaways * “I deliver an incredible workout that also happens to be rehabbing your body…physical therapy and exercise don’t have to be two different things.”– Ben Patrick * Removing pressure from your knee is actually a counterintuitive action + You’re communicating to your body that you don’t need that area to be robust with circulation and strength * Improving your mobility allows you to access new muscle tissue that you couldn’t hit before + Be willing to go backward before you go forwards + ATG (ass to grass) split squat is Ben’s favorite mobility exercise + Full range of motion exercises improve flexibility and strength * You have to be just as strong moving in reverse as you are going forward + “Get stronger in reverse of what hurts” – Ben Patrick * It’s really hard to be the person in the gym not doing the status quo exercise routine + But doing so is not only physically rewarding but also mentally. You’re building the resiliency to do what’s best for you. * Continue reading for Ben’s essential knee exercises

Read the full notes @ podcastnotes.org

Ben Patrick (Knees Over Toes Guy) is an athletic coach and an author.

Keeping our bodies bulletproof is something everyone wants as they age. Bad knees, backs and shoulders not only stop you from doing the things you want in sport, but then begin to suck the enjoyment out of your life too. Ben has some solutions.

Expect to learn the 3 most important exercises to maximise your body's robustness, what Ben's biggest takeaways have been from Andrew Huberman, the relationship between flexibility and strength, how to make your shoulders more mobile and less painful, the optimal training frequency to see results and much more...

Sponsors:

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Get in touch.

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Jocko Podcast

Podcast Notes Key Takeaways * The principles of philosophy can be gained both experimentally and educationally + This is the whole preface behind the conversation. Jocko sees Andrew Huberman as someone who can academically explain the science behind his instincts. + Part 1 of our Podcast Notes set the stage for the exploration of this intersection. * Learn about Andrew Huberman’s incredible life story, from a bum skateboarder to a Ph.D. in Neuroscience

Read the full notes @ podcastnotes.org

Andrew Huberman, Ph.D., is a neuroscientist and tenured Professor in the Department of Neurobiology at the Stanford University School of Medicine. He has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning.

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Huberman Lab

Podcast Notes Key Takeaways * Intermittent challenges or stressors to your system are good – humans are evolved for challenges, but today’s lifestyle has taken away most of the common struggles we experienced before * Three key nutrients for the brain and body: (1) sulforaphane; (2) omega-3; (3) vitamin D * Food sources of sulforaphane: broccoli (barely cooked), broccoli sprouts, moringa powder * “I personally think [omega-3 fish oil] is one of the most powerful anti-inflammatory things, dietary lifestyle things we can get easily that is going to powerfully modulate the way you think, the way you feel, and the way you age.” – Dr. Rhonda Patrick * Vitamin D is not just a vitamin! 70% of the US population is deficient – it’s worth measuring & supplementing to optimal bone health, immunity, hormone conversion, and more * There’s a strong dose-dependent nature of sauna use: people who use sauna 4-7x/week have a lower risk (60% reduction) of dementia and Alzheimer’s; people who use sauna 2-3x/week have a 20% reduction in risk * Heat stress mimics moderate cardiovascular exercise effect – this could be a great onramp for people who are otherwise unable to exercise due to disability or whatever reason * The cardiorespiratory system is improved in people who do both sauna and exercise compared to doing either alone * Stress & memory: if you’re too relaxed you won’t remember things as well; at peak levels of stress, you remember things better until you reach too high a level of panic

Read the full notes @ podcastnotes.org

My guest is Rhonda Patrick, Ph.D. She earned her doctoral degree in biomedical science from St. Jude Children’s Research Hospital at the University of Tennessee Health Science Center and has become one of the leading public health educators on the brain and general health, aging, cancer, and nutrition. We discuss the four major categories of micronutrients that regulate cellular and organ stress and antioxidants, inflammation, hormone regulation, immune system, and longevity. Dr. Patrick provides actionable protocols for obtaining key micronutrients from food and/or supplement-based sources. Additionally, Dr. Patrick outlines protocols for deliberate cold and deliberate heat exposure to benefit metabolism, cardiorespiratory fitness, mental health, and lifespan.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Momentous

https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Rhonda Patrick – Micronutrients, Cold & Heat Exposure

(00:03:12) Momentous Supplements

(00:04:27) The Brain-Body Contract

(00:05:30) AG1 (Athletic Greens), Thesis, InsideTracker

(00:09:42) Stress Response Pathways, Hormesis

(00:16:38) Plants, Polyphenols, Sulforaphane

(00:21:12) Tools 1: Sulforaphane - Broccoli Sprouts, Broccoli, Mustard Seed

(00:23:50) Tool 2: Moringa & Nrf2 Antioxidant Response

(00:25:25) Sulforaphane: Antioxidants (Glutathione) & Air Pollution (Benzene Elimination)

(00:27:10) Plants & Stress Response Pathways, Intermittent Challenges

(00:29:35) Traumatic Brain Injury, Sulforaphane, Nrf2

(00:35:08) Tools 3: Omega-3 Fatty Acids (ALA, EPA & DHA), Fish Oil, Oxidation

(00:48:40) EPA Omega-3s & Depression

(00:52:02) Krill Oil vs. Fish Oil Supplements?

(00:54:23) Benefits of Omega-3 Fatty Acids, Omega-3 Index & Life Expectancy

(00:59:24) Tool 4: Food Sources of EPA Omega-3s

(01:06:07) Omega-3 Supplementation, Omega-3 Index Testing

(01:10:22) Benefits of Omega-3s

(01:14:40) Tool 5: Food Sources of DHA Omega-3s

(01:17:07) Vitamin D & Sun Skin Exposure

(01:22:18) Role of Vitamin D, Gene Regulation

(01:25:30) Tool 6: Vitamin D Testing & Vitamin D3 Supplementation

(01:33:15) Tool 7: Skin Surface Area & Sun Exposure, Vitamin D

(01:34:23) Vitamin D & Longevity

(01:36:46) Sun Exposure & Sunscreen

(01:40:30) Role of Magnesium, Magnesium Sources, Dark Leafy Green Vegetables

(01:44:50) Tool 8: Magnesium Supplements: Citrate, Threonate, Malate, Bisglycinate

(01:50:57) Tool 9: Deliberate Cold Exposure Protocol & Mood/Anxiety

(01:59:22) Tool 10: Cold Exposure, Mitochondria UCP1 & Heat Generation

(02:02:30) Tool 11: Cold & Fat ‘Browning’, PGC-1alpha, Metabolism

(02:05:08) Cold Exposure & High-Intensity Interval Training (HIIT), PGC-1alpha, Muscle

(02:08:04) Tools 12: Exercise, HIIT, Tabata & Sauna

(02:13:30) Tool 13: Sauna, Endorphins/Dynorphins, Mood

(02:17:45) Tool 14: Mild Stress, Adrenaline & Memory

(02:19:53) Sauna, Vasodilation & Alzheimer’s and Dementia Risk

(02:25:30) Sauna Benefits, Cardiorespiratory Fitness, Heat Shock Proteins (HSPs)

(02:31:29) Insulin signaling, FOXO3 & Longevity

(02:33:22) Tools 16: Sauna Protocols, Hot Baths & Fertility

(02:37:41) Tool 17: Exercise & Longevity, Osteocalcin

(02:41:37) Tools 18: Red Light Sauna? Infrared Sauna? Sauna & Sweating of Heavy Metals

(02:47:20) FoundMyFitness Podcast, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Patreon, Momentous Supplements, Huberman Lab on Instagram & Twitter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Philosophize This!

Podcast Notes Key Takeaways * Check out Philosophize This! Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Today we continue our discussion of Emerson.

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Artificial Intelligence Podcast

Michael Saylor is the CEO of MicroStrategy and a prominent holder and proponent of Bitcoin. Please support this podcast by checking out our sponsors: – Scale: https://scale.com/lex – Coinbase: https://coinbase.com/lex to get $10 in free Bitcoin – Audible: https://audible.com/lex to get $9.95 a month for 6 months – NetSuite: http://netsuite.com/lex to get free product tour – SimpliSafe: https://simplisafe.com/lex and use code LEX EPISODE LINKS: Michael’s Twitter: https://twitter.com/saylor MicroStrategy: https://microstrategy.com/ Michael’s Book: https://amzn.to/37J2iA0 Book mentioned: https://amzn.to/3jwsIaP PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out

The Bitcoin Standard: The Decentralized Alternative to Central Banking

The Mobile Wave: How Mobile Intelligence Will Change Everything

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a16z Live

Podcast Notes Key Takeaways * Check out a16z Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Katherine Boyle, General Partner at a16z is joined by Hadrian founder and CEO Chris Power, Packy McCormick, founder of Not Boring, and a16z co-founder Marc Andreessen to discuss the opportunity to automate and upskill in the precision parts industry and shore up U.S. manufacturing with new technology.

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Hidden Brain ✓

Claim

Neuroscientist Doug Fields was on a trip to Europe when a pickpocket stole his wallet. Doug, normally mild-mannered, became enraged — and his fury turned him into a stranger to himself. This week, we revisit a favorite 2020 episode about the secret logic of irrational anger.

If you like this show, please check out our new podcast, My Unsung Hero! And if you'd like to support our work, you can do so at support.hiddenbrain.org.

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Huberman Lab

Podcast Notes Key Takeaways * Regular use of sauna and other heat exposure can reduce mortality by cardiovascular events, stroke, and all-cause mortality * Effects of deliberate heat mimic cardiovascular exercise * General guideline to start heat stimulus: temperature must be between 176F-212F for 5-20 minutes, 2-7 times per week – later in the day is better to activate cooling mechanisms and assist with sleep * Find what works for you: choose either higher heat intensity and shorter bouts, or lower heat intensity and longer bouts – but always between 176F-212F * Make sure you’re replacing the water you lose in the sauna – drink at least 16 ounces of water for every 10 minutes of sauna use * If growth hormone increase is your main goal for sauna use, limit to 1x/week or 1x/10 days – and enter fasted or without food in the 2-3 hours prior for maximum benefits * Proper application of local heat may actually change the identity of fat cells at that location and encourage the conversion of white fat to beige fat

Read the full notes @ podcastnotes.org

I describe the mechanisms by which deliberate heat exposure impacts body temperature, metabolism, heart health, hormone production, exercise recovery, cognition, mood, and longevity. I detail specific protocols for deliberate heat exposure, including exposure times, temperature ranges to consider, time of day, and delivery mechanisms (sauna vs. hot bath vs. open air heat, etc.) in order to achieve different specific outcomes, including dramatic growth hormone releases, or reduction in cortisol levels. I also discuss the ability of locally applied heat to heal or otherwise improve various bodily tissues and new data on how local application of heat may induce the conversion of metabolically sluggish white fat to metabolically robust beige fat.

Thank you to our sponsors

LMNT: https://drinklmnt.com/huberman

InsideTracker: https://insidetracker.com/huberman

ROKA - https://www.roka.com - code "huberman"

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Momentous

I am pleased to announce that the Huberman Lab Podcast is now partnered with Momentous. Momentous supplements are of the very highest quality; each is third-party tested for purity and accuracy of dosage. To learn more about the Huberman Lab Podcast-Momentous partnership, the supplements I that take, and stay up-to-date with future product announcements, visit: https://www.livemomentous.com/huberman.

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Heat & Health

(00:03:37) Momentous Supplements

(00:04:52) The Brain-Body Contract

(00:05:46) LMNT, InsideTracker, ROKA

(00:09:31) Body Shell Temperature vs. Body Core Temperature

(00:13:28) Thermal Regulation, Hyperthermia

(00:17:36) Heat Removal Circuits, Pre-Optic Hypothalamus (POA)

(00:26:30) Protocols & Benefits of Deliberate Heat Exposure

(00:33:37) Tools & Conditions for Deliberate Heat Exposure

(00:38:47) Deliberate Heat Exposure, Cortisol & Cardiovascular Health

(00:44:50) Heat Shock Proteins (HSPs), Molecular Mechanisms of Heat Regulation

(00:47:56) Longevity & Heat Exposure, FOXO3

(00:52:30) Deliberate Cold & Heat Exposure & Metabolism

(00:54:48) Deliberate Heat Exposure & Growth Hormone

(01:04:32) Parameters for Heat & Cold Exposure

(01:08:26) Circadian Rhythm & Body Temperature, Cold & Heat Exposure

(01:12:00) Heat Exposure & Growth Hormone

(01:16:20) Tool: Hydration & Sauna

(01:17:10) Heat, Endorphins & Dynorphins, Mood

(01:28:44) Tool: Glabrous Skin To Heat or Cool

(01:35:33) Local Hyperthermia, Converting White Fat to Beige Fat, Metabolism

(01:47:00) Hormesis/Mitohormesis & Heat/Cold Exposure

(01:49:11) Benefits of Heat Exposure

(01:51:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Infinite Loops

Podcast Notes Key Takeaways * “We are deterministic thinkers living in a probabilistic world, hilarity or tragedy often ensue”– Jim O’Shaughnessy + Many of 10-K Diver’sTwitter threads point out the faults in deterministic thinking by analyzing mathematics and using first principles thinking to study financial concepts + We often ask the wrong questions – this thread is a great example * Studying history can save you from FOMO investing + In the 1900s, there were 200 car manufacturers. Obviously, only a few survived. Knowing this context can help you slow down your decision-making before rushing into the next hyped tech stock. * Always work through the numbers before ever opening your mouth + If you think you know something, write it out. You’ll more often than not realize that you’re not prepared to speak about it yet. + Intuitions can lead you astray from the truth and even your actual opinion on something * 10-K Diver thinks Warren Buffett’s and Charlie Munger’s buy-and-hold philosophies get overgeneralized, leading to misconceptions about their actual investment strategies

Read the full notes @ podcastnotes.org

As Chamath Palihapitiya put it back in April 2021, 10-K Diver is “one of the best fintwit accounts on Twitter.” 10-K Diver loves breaking down complex financial topics and helping people understand them via engaging Twitter threads.

You can follow 10-K Diver on Twitter at https://twitter.com/10kdiver and read all his threads at https://10kdiver.com/twitter-threads/

Show Notes:

Curating aggressively
Is there a long term plan?
Reasoning from the first principles
Volatility tax
Do markets have a memory?
Financial Independence, Retire Early (FIRE)
Mental models for investing
Premeditating
Jim’s GIF game
Is it a Lindy or a turkey?
The ‘Money Concepts’ show
Benefits and pitfalls of leverage
What’s next for the 10-K diver?

Books Mentioned:

Reminiscences of a Stock Operator; by Edwin Lefèvre
Happy; by Derren Brown

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Nudge - Marketing Science Simplified✓Claim

Podcast Notes Key Takeaways * “When we think of influence, we think of influences. But, we rarely think about ourselves. We don’t tend to think about the influence we naturally have, which is why you probably have more influence than you think.”– Phill Agnew + Influence is so much more than social media engagement, it’s about understanding the psychology of your interactions + Allowing yourself to look past your biases will reveal the natural influence you have in your everyday life * Vanessa and Phill explore the everyday biases that hold us back from seeing our natural influence: + The Invisibility Cloak Illusion: Tendency to (incorrectly) believe that you notice people more than they notice you + The Spotlight Effect: Tendency to overestimate how much others notice aspects of one’s appearance or behavior + And more! * “Basing your happiness on comparisons isn’t helpful because we are hopeless at setting reliable benchmarks for those comparisons”– Phill Agnew + It can’t be logically true for the average person to think they are less social than the average person * Engage more and worry less about getting things perfect + The positive outcomes almost always outweigh the negative + Don’t be limited by perception—it’s usually incorrect anyway

Read the full notes @ podcastnotes.org

When you think of influence you probably think of Beyonce, Ronaldo, or Obama. But you don’t think about yourself. In today’s show, Professor Vanessa Bohns talks about the influence you already have. She explains why we underestimate how many people like our company, why we overestimate how social our friends are, and how we change our views depending on who we’re talking to. Tune in and I guarantee you’ll learn something surprising about yourself.

Vanessa’s book: https://www.vanessabohns.com/

Follow Vanessa on Twitter: https://twitter.com/profbohns

Sign up for the Nudge Newsletter: https://www.nudgepodcast.com/mailing-list

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Modern Wisdom

Nick Maggiulli is the Chief Operating Officer for Ritholtz Wealth Management and an expert in personal finance using data analysis.

Saving money and building wealth are some of the most popular content on the internet. But what are the absolute best ways to maximise your fortune? Nick has broken down the complex world of personal finance to find out what the data says about different strategies.

Expect to learn why earning more is better than spending less, why buying the dip is a losing strategy, the easiest way to invest in the stock market, how to spend money guilt-free, why almost everyone has a backward retirement strategy, how to tell when you should sell, what the Vanderbilt's lost fortune can teach us about spending money and much more...

Sponsors:

Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/

Get 30% discount on your at-home testosterone test at https://trylgc.com/modern (use code: MODERN30)

Get perfect teeth 70% cheaper than other invisible aligners from DW Aligners at http://dwaligners.co.uk/modernwisdom (use code MODERN10)

Get 5 Free Travel Packs, Free Liquid Vitamin D and Free Shipping from Athletic Greens at https://athleticgreens.com/modernwisdom (discount automatically applied)

Extra Stuff:

Buy Just Keep Buying - https://amzn.to/3OcdXID

Check out Nick's blog - http://ofdollarsanddata.com/

Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/

To support me on Patreon (thank you): https://www.patreon.com/modernwisdom

-

Get in touch.

Instagram: https://www.instagram.com/chriswillx

Twitter: https://www.twitter.com/chriswillx

YouTube: https://www.youtube.com/modernwisdompodcast

Email: https://chriswillx.com/contact/

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Knowledge Project

What are the best strategies to get people to say “Yes” to your requests in life? Acclaimed psychologist Robert Cialdini dives deep into the seven small things that make a huge impact in influencing others, as well as the difference between being influenced and being manipulated into making decisions. What are the tactics, how do they work, and how do we defend against them? This episode is jam-packed with practical advice that will make you more persuasive in life.

Known colloquially as “The Godfather of Influence,” Cialdini is a foundational expert in the science of influence and how to apply it ethically in business. His books, including Influence: Psychology of Persuasion and Pre-Suasion, have sold more than 7 million copies in 44 different languages, and he is the Regents’ Professor Emeritus of Psychology and Marketing at Arizona State University.

--
Go Premium and get the full episode. Members get early access, ad-free episodes, hand-edited transcripts, searchable transcripts, member-only episodes, and more. Sign up at: https://fs.blog/membership/

Every Sunday our newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Huberman Lab

Podcast Notes Key Takeaways * Light can change the genes that the cells of the body express directly and indirectly * There are more than 100 years of science supporting the use of specific types of light to support the health of the brain and body * Different wavelengths of light impact our tissues at different levels – shortwave light (e.g., blue, UV) doesn’t penetrate beyond the top surface of the skin; longwave light (e.g., red) penetrates deep through the skin to bone * Think of light as a communicator of what’s going on in the environment around you and either taken at the surface or deeper and passed off as instructions to other areas or organs of the body * Tip: if you wake up in the middle of the night, try not the flip on a light (or use longwave light) so you don’t disrupt melatonin levels * Sunlight and day length can impact the melatonin pathway and directly trigger hormone pathways (testosterone and estrogen), desire to mate, and mating behavior * Using light to optimize testosterone and estrogen: get about 20 minutes of light exposure to as much skin as possible, 2-3 times per week minimum * Experiencing pain? Go outside & get direct UVB light on the skin and in the eyes! On longer days or in bright light environments, we tolerate pain (nociception) better * Benefits of direct UVB exposure on eyes & skin: enhanced immune function, increased turnover (growth) of stem cells in hair and nails, sleep regulation, faster wound healing, increases in hormones * Tip for shift workers or people awake at night for childcare, etc.: if you need to be awake at night, red light is the best choice because it will not inhibit melatonin or increase cortisol * Obvious but worth stating: when we talk about light exposure to the eyes, it shouldn’t be painful to look at or force you to squint or turn away – it’s too bright to safely look at if that’s the case

Read the full notes @ podcastnotes.org

I describe the mechanisms by which different wavelengths of light impact the cells, tissues and organs of the human body, and how specifically timed light exposure of specific wavelengths can be used to improve sleep, enhance alertness, modulate hormone levels, and improve mood. I also explain the use of ultraviolet and infrared phototherapies to relieve pain increase testosterone and estrogen levels; improve skin health, appearance and wound healing; and how red light can be used to offset age-related vision loss and provide neuroprotection. Throughout the episode, I describe the mechanisms of light-based therapies and actionable tools that people can use positively impact mental and physical health.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

Thesis: https://takethesis.com/huberman

LMNT: https://drinklmnt.com/huberman

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Thorne

https://www.thorne.com/u/huberman

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Using Light to Improve Health

(00:04:31) The Brain-Body Contract

(00:05:17) AG1 (Athletic Greens), Thesis, LMNT

(00:09:56) Physics of Light, Electromagnetic Energy

(00:12:23) Wavelengths of Light

(00:15:38) How Light Penetrates Tissues

(00:20:13) Light & the Body: Direct & Indirect Signals

(00:28:35) Light, Seasonality & Melatonin

(00:33:40) Melatonin: Regulatory & Protective Effects

(00:38:49) Tools: Optimizing Melatonin Levels

(00:44:49) Sun (UVB light) Exposure, Mating Behavior, Testosterone & Estrogen

(00:58:09) Seasonality, Romantic Passion & Testosterone

(01:02:13) Tool: Skin Sun Exposure & Testosterone

(01:06:13) Light & Improved Pain Tolerance

(01:11:55) Protocol: Sun Exposure & Chronic Pain

(01:12:48) Tools: Sunlight (UVB), Blue-Light Blockers, Seasonal Affective Disorder (SAD)

(01:19:44) Light & Enhanced Immune Function

(01:23:30) Tool: Light During Winter Months

(01:26:18) Light Therapies: Local vs. Systemic Exposure

(01:28:54) Tool: Improving Mood, Timing of Natural & Artificial Light

(01:32:44) Light Conditions & Sleep Optimization

(01:39:00) Infrared Light, Skin & Wound Healing

(01:46:00) Infrared Light Therapy & Skin, Low-Level Laser (Light) Therapy (LLLT)

(01:49:20) Infrared Light & Age-Related Vision Loss

(01:59:36) Tools: Infrared Panels, Morning Exposure

(02:05:22) Infrared Light at Night, Shift Work

(02:08:35) Light Flicker Phototherapy & Neuroprotection

(02:19:07) Phototherapies for Health

(02:20:50) Zero-Cost Support, YouTube Feedback, Spotify Reviews, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Neural Network Newsletter, Brain-Body Contract

Title Card Photo Credit: Mike Blabac

Disclaimer

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * Before recording his podcast, Huberman takes a walk to estimate his energy levels + While walking, he recites/sings the lyrics of a song he likes out loud + The process calms him down, makes him more focused, and warms up his vocal cords * “The reach of the podcast [ Huberman Lab ] is really fascinating, it’s not the numbers of the listeners, it’s the depth of connection you have with certain people.” – Lex Fridman * It’s not just about freedom of speech to say controversial things it’s also freedom of speech to be weird, e.g. Ellon Musk posting sex memes + Huberman likes the idea of authenticity without oversharing + People lose careers based on the movement of their thumbs (inappropriate online behavior) * “As an educator in the classroom but also on social media my absolute favorite thing is when the comments about other people’s comments are positively reinforcing so you see people having conversations within the comments.”– Andrew Huberman * Non-Sleep Deep Rest (NSDR) – a term coined by Huberman – involves different techniques that bring the brain and body into a state of relaxation + Distinctly different from meditation + Terrific at allowing people to learn to shift their state of consciousness, reset energy levels and focus * Reveri (self-hypnosis app) + Huberman uses it to achieve a state of deep relaxation if he can’t sleep + Search Youtube for NSDR scripts - Check out Madefor, Michael Seeley for long hypnosis scripts (free) + The more you do them the more quickly you can shift your brain into a state of deep relaxation * “The best thing that anyone can do for their mental health physical health and performance in athletic or cognitive endeavors or creative endeavors is to make sure that you’re getting enough quality sleep.” – Andrew Huberman * Binaural beats of 40 hertz can shift the brain into a heightened state of focus and cognition * Ritalin, Adderall – don’t use them without a prescription (hits the dopamine system way too hard) * Where you place your screen is important; place it at eye level or above you * The only really hard part of a good relationship is dealing with oneself and taking good care of the other person

Read the full notes @ podcastnotes.org

Andrew Huberman is a neuroscientist at Stanford and host of the Huberman Lab Podcast. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – LMNT: https://drinkLMNT.com/lex to get free sample pack – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit – MasterClass: https://masterclass.com/lex to get 15% off EPISODE LINKS: Andrew’s YouTube: https://youtube.com/AndrewHubermanLab Huberman Lab Podcast: https://hubermanlab.com Andrew’s Twitter: https://twitter.com/hubermanlab Andrew’s Instagram: https://instagram.com/hubermanlab PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: –

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The Danny Miranda Podcast

Podcast Notes Key Takeaways * Check out The Danny Miranda Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

(0:00) Sahil compliments me

(0:45) Crazy coincidence

(2:40) Sahil’s been plugging his Twitter since 2011

(3:44) Why Sahil is attracted to motivational tracks

(6:31) Obesity research at Nike

(11:40) The transition from arrogance to kindness

(15:25) Identity (Indian + Jewish parents, nerd + jock)

(18:27) 10-year reunion

(20:14) Practices that made Sahil more secure?

(21:39) Darkest hour friend

(25:15) What to say in dark times to a friend?

(27:15) How to accept compliments

(28:08) “I appreciate you”

(30:05) Why Sahil microanalyses life

(32:00) Condoleezza Rice

(36:29) Cold email

(37:38) Going to the gym with Tim Cook

(39:20) Why is Sahil so connected to highly successful people

(46:30) What can someone do today to show grit and work ethic?

(50:02) Zone of genius

(59:15) How to single focus

(1:00:55) More walks without tech

(1:03:10) Connecting with Sahil

Sahil Bloom is an investor, entrepreneur, and creator. In less than 2 years, Sahil has gained over 500,000 Twitter followers. But in this episode, we didn't focus that much on his hyper-growth online. Instead, we spoke about how Sahil got mentored by BOTH Tim Cook and Condoleezza Rice, how Sahil became more secure in himself, and what it means to be a "darkest hour friend."

Sahil's Twitter – https://twitter.com/SahilBloom

Continue the conversation with me...

🎙 Podcast: https://podfollow.com/1532160275

🐣 Twitter: https://twitter.com/heydannymiranda

📸 Instagram: https://instagram.com/heydannymiranda

🕺 TikTok: https://tiktok.com/@heydannymiranda

🚨 Newsletter: https://dannymiranda.com/tuesday-treasure/

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BiggerPockets Real Estate Podcast

Inflation and cash flow have been fighting against each other for decades. As soon as you increase the rent on an income property, inflation comes right in to eat some of that gain. So in today’s borderline hyperinflationary environment, is cash flow still coming out on top? A better question to ask may be, what happens in five, ten, or twenty years? Will inflation completely erode your financial freedom dreams? Or will cash flow match (or beat) this destructive force.

This isn’t just a question that impacts real estate investors—it affects almost every individual working within today’s economy. In today’s episode of Seeing Greene, David goes deep into this question (and others) so you, the investors, can have a better understanding of our economy as a whole. You’ll also hear topics like whether or not you can transfer title on an FHA loan, what to do when bidding wars push prices well above market comparables, when to cosign and when to ask for a cosigner, and what every investor in their twenties should start doing today.

Heard a topic that you wanted more explanation on? Want to ask David a question you’ve never heard before? If so, submit your question here so David can answer it on the next episode of Seeing Greene. Hop on the BiggerPockets forums and ask other investors their take, or follow David on Instagram to see when he’s going live so you can hop on a live Q&A and get your question answered on the spot!

In This Episode We Cover:

How spending power changes the way investors calculate cash flow

Transferring title from your personal name into an LLC with an FHA loan

How to know a house is “worth it” and what to look for in a loan officer

Cosigning for a relative to house hack and staying up-to-code with owner-occupied loans

Pivoting markets from a cash flow market to an appreciation market

David’s advice to every young, aspiring real estate investor

And So Much More!

Links from the Show

BiggerPockets Youtube Channel

BiggerPockets Forums

BiggerPockets Pro Membership

BiggerPockets Bookstore

Submit Your Questions to David Greene

BiggerPockets Podcast 567: Seeing Greene: Finding Cash Flow, Refinancing Sooner, & NNN Properties

BiggerPockets Podcast 570: Seeing Greene: Signs of a Great Agent, When to Refi, and How to Scale

BiggerPockets Podcast 571: Is This Deal Worth My Time? The 6 Crucial Steps to Vet a Multifamily Sea

BiggerPockets Podcast 577: Cutting Your Tax Bill, Investing in Different Markets, & “Investor Pressure” | Coaching Calls

BiggerPockets Podcast 582: Seeing Greene: Investing in Paradise, Timing the Market, and House Hacking

BiggerPockets Podcast 585: Seeing Greene: Boosting Your Appraisal, Backward BRRRRs, & Capital Raising Risks

BiggerPockets Podcast 588: Seeing Greene: Climate Change, ADU Dilemmas, & Retiring with Rentals

BiggerPockets Podcast 591: Seeing Greene: The Cash Flow Market “Mirage” That Traps New Investors

David Greene Meetups

David Greene Team

Click here to check the full show notes: https://www.biggerpockets.com/blog/real-estate-594

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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Huberman Lab

Podcast Notes Key Takeaways * Six pillars of hormone health: (1) diet (specifically caloric restriction); (2) exercise (specifically resistance training); (3) stress & stress optimization; (4) sleep optimization; (5) sunlight; (6) spirit – dial in the body, mind, and soul connection * Think of yourself as a Venn diagram: you have a body, mind, and soul – you can’t completely be well if you’re missing the health of one area * Tip to get your doctor to order more bloodwork than the basic panel: tell your doctor your (fill in the blank) – energy, sleep, endurance, etc. – is not as good as it used to be * High alcohol intake and smoking marijuana will ultimately decrease testosterone * Caffeine has a negligible effect on hormones * Vegans: you are possibly at risk of not getting enough of certain types of fats and nutrients to maintain a proper ratio of testosterone to estrogen – supplement with algae or other healthy fats * To naturally increase growth hormone output: don’t eat within 2 hours of sleep, get good deep sleep, resistance exercise early in the day, manage stress * A word of caution about peptides: work with a physician! There are so many bad quality peptides with detrimental side effects

Read the full notes @ podcastnotes.org

My guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health and well-being in both men and women. We discuss how to improve hormones using behavioral, nutritional, and exercise-based tools and safely and rationally approach supplementation and hormone therapies. We discuss testosterone and estrogen and how those hormones relate to fertility, mood, aging, relationships, disease pathologies, thyroid hormone, growth hormone, prolactin, dopamine and peptides that impact physical and mental health and vitality across the lifespan. The episode is rich with scientific mechanisms and tools for people to consider.

Thank you to our sponsors

Thesis: https://takethesis.com/huberman

InsideTracker: https://insidetracker.com/huberman

ROKA: https://roka.com - use code "huberman"

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Thorne

https://www.thorne.com/u/huberman

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Kyle Gillett, MD, Hormone Optimization

(00:03:10) The Brain-Body Contract

(00:04:10) Thesis, InsideTracker, ROKA

(00:08:24) Preventative Medicine & Hormone Health

(00:14:17) The Six Pillars of Hormone Health Optimization

(00:17:14) Diet for Hormone Health, Blood Testing

(00:20:21) Exercise for Hormone Health

(00:21:06) Caloric Restriction, Obesity & Testosterone

(00:23:55) Intermittent Fasting, Growth Hormone (GH), IGF-1

(00:29:08) Sleep Quality & Hormones

(00:35:03) Testosterone in Women

(00:38:55) Dihydrotestosterone (DHT), Hair Loss

(00:43:46) DHT in Men and Women, Turmeric/Curcumin, Creatine

(00:50:10) 5-Alpha Reductase, Finasteride, Saw Palmetto

(00:52:30) Hair loss, DHT, Creatine Monohydrate

(00:55:07) Hair Regrowth, Male Pattern Baldness

(00:58:12) Polycystic Ovary Syndrome (PCOS), Inositol, DIM

(01:04:00) Oral Contraception, Perceived Attractiveness, Fertility

(01:10:31) Testosterone & Marijuana or Alcohol

(01:14:27) Sleep Supplement Frequency

(01:15:34) Testosterone Supplementation & Prostate Cancer

(01:20:24) Prostate Health, Dietary Fiber, Saw Palmetto, C-Reactive Protein

(01:24:05) Prostate Health & Pelvic Floor, Viagra, Tadalafil

(01:30:54) Testosterone Replacement Therapy (TRT)

(01:35:17) Estrogen & Aromatase Inhibitors, Calcium D-Glucarate, DIM

(01:39:28) Lifestyle Factors to Increase Testosterone/Estrogen Levels, Dietary Fats

(01:45:34) Aromatase Supplements: Ecdysterone, Turkesterone

(01:47:04) Tongkat Ali (Long Jack), Estrogen/Testosterone levels

(01:52:25) Fadogia Agrestis, Luteinizing Hormone (LH), Frequency

(01:56:44) Boron, Sex Hormone Binding Globulin (SHBG)

(01:58:13) Human Chorionic Gonadotropin (hCG), Fertility

(02:04:18) Prolactin & Dopamine, Pituitary Damage

(02:08:34) Augmenting Dopamine Levels: Casein, Gluten, Vitamin E, Vitamin B6 (P5P)

(02:12:30) L-Carnitine & Fertility, TMAO & Allicin (Garlic)

(02:18:19) Blood Test Frequency

(02:19:41) Long-Term Relationships & Effects on Hormones

(02:25:33) Nesting Instincts: Prolactin, Childbirth & Relationships

(02:29:05) Cold & Hot Exposure, Hormones & Fertility

(02:32:34) Peptide Hormones: Insulin, Tesamorelin, Ghrelin

(02:37:24) Growth Hormone-Releasing Peptides (GHRPs)

(02:39:38) BPC-157 & Injury, Dosing Frequency

(02:45:23) Uses for Melanotan

(02:48:21) Spiritual Health Impact on Mental & Physical Health

(02:54:18) Caffeine & Hormones

(02:56:19) Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Review, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Brain-Body Contract

Title Card Photo Credit: Mike Blabac

Disclaimer

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Naval's Podcast and Periscope Sessions

Introduction 0:00

Haseeb’s background 0:22

Vitalik’s background 2:43

A blockchain you can build any app on top of 7:02

Eth trades efficiency for transparency 10:18

Like plain text, Eth is simple and efficient 12:41

Only high-value transactions can afford the blockchain 13:08

Doing away with ‘trusted’ third parties 14:09

Trading performance for security 14:43

‘Impregnable castles made of math’ 16:23

Ethereum’s limitations are latency and privacy 16:56

There are ways to get back your privacy 19:32

Can Eth provide a high level of decentralization and a high level of scaling at the same time? 20:39

Sharding leads to more centralization 21:49

Verifiability at the expense of scaling 24:00

How much decentralization is the right amount? 25:11

What happens when subsidies to join nodes disappear? 27:07

Stateless clients make it possible to verify the chain with very little on your hard drive 28:18

Staking culture is difficult to cultivate 28:52

New blockchain players tend to go for minimum viable decentralization 29:54

People don’t value privacy until somebody goes to jail over it 30:32

Eth is ‘simple at the base’ 31:12

Social recovery wallets make it easier to be your own bank 31:44

Block space is getting expensive 32:41

There’s not a lot of innovation on Bitcoin, by design 33:35

Blockchain’s ‘free-rider effect’ 34:57

Innovation is slowest at Layer 1 35:34

Layer 2 moves faster because it’s permissionless 36:59

What if we froze Layer 1 today? 37:25

Data for computation trade-off 38:57

Benchmarking blockchains apples-to-apples 40:02

Enshrining decentralization 41:43

Tensions between scaling and preserving value 42:27

There will be multiple stores of value 43:54

—

Transcript http://nav.al/vitalik

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ADHD Experts Podcast ✓

Claim

Podcast Notes Key Takeaways * Check out ADHD Experts Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Behaviors like setting unrealistic goals and insisting on personal flawlessness point to a cycle of perfectionism. Join Sharon Saline, Psy.D., to learn more about the relationship between anxiety, perfectionism, and ADHD and how to nurture a growth mindset.

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * “It seems like music has the ability to bring us so much depth in our soul that’s hard to access any other way”– Rick Rubin + The beauty of music is its open interpretation + The artist and the listener do not have to share the same meaning or experience * There are no rules to music, every idea deserves its own opportunity for trial and error + New ideas often sound bad until they are attempted + The ideas that breakthrough rarely breakthrough in the predicted way. So give your ideas a chance! You never know how it will turn out. * Production and performance are two very different things + “The best version is when someone is feeling something internally and we’re capturing it. The other version is they are performing for someone.” – Rick Rubin + The best recordings happen in an intimate and isolated setting where the stakes are low * Don’t listen to anyone, make the things that you love, whatever they may be. Make it for an audience of one—you. + “You can’t make art with someone else in mind, I don’t believe it can be good” – Rick Rubin * Continue reading for countless quotes that music lovers from all genres can relate to. Rick Rubin is truly a legend of the industry.

Read the full notes @ podcastnotes.org

Rick Rubin is one of the greatest music producers of all time, working with many of the greats including Beastie Boys, Eminem, Metallica, LL Cool J, Kanye West, Slayer, Tom Petty, Johnny Cash, Dixie Chicks, Aerosmith, Adele, Danzig, Red Hot Chili Peppers, System of a Down, Jay-Z, Black Sabbath. Please support this podcast by checking out our sponsors: – Lambda: https://lambdalabs.com/lex – Theragun: https://therabody.com/lex to get 30 day trial – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Onnit: https://lexfridman.com/onnit to get up to 10% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to

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Huberman Lab

Podcast Notes Key Takeaways * Check out the Huberman Lab Episode Page & Show Notes

Read the full notes @ podcastnotes.org

I describe mechanisms by which deliberate cold exposure can enhance mental health, physical health, and performance. I detail specific protocols to safely engage in deliberate cold exposure, including minimal exposure times, time-of-day effects, determining optimal temperatures, recovery, mindset, and movement during cold exposure. I discuss how cold exposure can be used to safely stress the body to improve attention, mood, and cognitive focus and boost metabolism and reduce inflammation. Also, I explain how cold exposure on specific regions of the body (called glabrous skin surfaces) can be leveraged to enhance endurance and weight training and increase work output.

Thank you to our sponsors

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See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Thorne

https://www.thorne.com/u/huberman

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Deliberate Cold Exposure, Health Warning

(00:04:23) Tool: Moderate Exercise & Cognitive Work

(00:10:47) The Brain-Body Contract

(00:11:32) AG1 (Athletic Greens), ROKA, Helix Sleep

(00:15:37) Circadian Rhythm & Body Temperature

(00:18:41) Tool: Quickly Decrease Core Body Temperature, Glabrous Skin

(00:25:26) Mental Effects of Cold Exposure

(00:29:02) Physical Effects of Cold Exposure

(00:30:11) How Cold Should the Temperature Be?

(00:34:53) Cold Showers vs. Cold Water Immersion

(00:38:27) Protocols for Cold Exposure

(00:50:57) Optimal Mindset(s) During Cold Exposure

(00:55:26) Tool: Using Movement During Cold Exposure

(00:57:51) Optimal Frequency of Cold Exposure

(01:00:22) Cold Exposure for Dopamine, Mood & Focus

(01:12:55) Cold Exposure & Metabolism, Brown Fat

(01:25:55) Tool: Caffeine, Dopamine & Cold Exposure

(01:29:14) Tools: Increasing Metabolism w/Cold – The Søberg Principle, Shivering

(01:34:15) Norepinephrine & Fat Cells

(01:36:22) Cold, Physical Performance, Inflammation

(01:47:36) Hyperthermia & Glabrous Skin Cooling

(01:53:27) Tool: Palmar Cooling & Endurance

(02:03:18) Cold Exposure to Groin, Increasing Testosterone

(02:07:50) Tool: Optimal Timing for Daily Cold Exposure

(02:11:16) Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Reviews, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter

Title Card Photo Credit: Mike Blabac

Disclaimer: The Huberman Lab Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

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Art of Manliness

Podcast Notes Key Takeaways * Check out The Art of Manliness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Do you ever feel like the time we live in feels flat, complacent, timid, conformist, populated by people who are focused on playing it safe and are inwardly empty?

A century and a half ago, the Danish philosopher Soren Kierkegaard felt the same way about the period in which he lived, and posited that there are two kinds of ages: the revolutionary, decisive, and passionate, and the sensible, rational, and reflective.

Here to unpack Kierkegaard’s ideas on these two kinds of ages is Jacob Howland, retired professor of philosophy and author of Kierkegaard and Socrates. Today on the show, Jacob and I first discuss some background on Kierkegaard and his existential philosophy. We then get into the differences between an age of passion and an age of reflection. We discuss how in a passionate age, an individual stands as an individual, possesses an energy which focuses on truth and ideals, and has the courage to take bold leaps of faith, while in a reflective age, the individual is subsumed by the crowd, is afraid of public opinion, and gets so lost in analysis and abstraction that he never makes a decisive move. All along the way, we delve into how Kierkegaard’s description of his age parallels our own, and Kierkegaard’s evergreen call to be an individual, embrace risk, and own your opinions and actions.

Resources Related to the Podcast Works by Kierkegaard mentioned in the show: + Two Ages: A Literary Review + Either/Or + Fear and Trembling + The Sickness Unto Death + Philosophical Fragments + Concluding Unscientific Postscript on Philosophical Fragments * Thomasine Christine Gyllembourg-Ehrensvärd * Georg Wilhelm Friedrich Hegel * On the Advantage and Disadvantage of History for Life* by Friedrich Nietzsche * “Yes, Sabermetrics Ruined Baseball” * AoM Article: Your Three Selves and How Not to Fall Into Despair * AoM Article: An Intro to Envy * AoM Podcast #635: The Existentialist’s Survival Guide

Connect With Jacob Howland* Jacob’s Website

Penguin Classics Fear and Trembling: Dialectical Lyric By Johannes De Silentio (Penguin Pocket Hardbacks)

On the Advantage and Disadvantage of History for Life (Hackett Classics)

The Two Ages : Kierkegaard's Writings, Vol 14 (Kierkegaard's Writings, 53)

The Sickness unto Death: A Christian Psychological Exposition of Edification & Awakening by Anti-Climacus (Penguin Classics)

Either/Or: A Fragment of Life (Penguin Classics)

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Art of Manliness

When neurologist and sleep specialist Dr. Chris Winter sees adult patients in his sleep clinic, they often come to him because of a struggle with insomnia, which, as he described in a previous appearance on the AoM podcast, is caused by stressing too much about sleep, so that going to bed becomes an anxious and fear-inducing routine that sabotages the natural needs and rhythms of the sleep cycle.

Chris would see fewer adult patients like this if, when they were kids, their parents set them up to have a healthy relationship with sleep.

How to establish that kind of healthy relationship is something Chris writes about in his latest book, The Rested Child, and is the topic of our conversation today. Chris will take us through what parents should know about their kids' sleep from the womb through young adulthood, with tips on both how to improve your children's sleep, and how to avoid messing it up, including his take on co-sleeping, why he let his kids go to bed whenever they wanted, and why he discourages giving children melatonin to help them sleep.

Resources Related to the Podcast* Chris' last appearance on the show — episode #661: Get Better Sleep By Stressing About It Less * National Sleep Foundation's graph and write-up of sleep duration recommendations across the lifespan

Connect With Dr. Chris Winter* Chris on Instagram * Chris on Twitter

The Rested Child: Why Your Tired, Wired, or Irritable Child May Have a Sleep Disorder--and How to Help

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * Long prolonged war is hardly ever positive-sum; the costs almost always outweigh the implied justice + “Fighting is just politics by other means–inefficient, devastating, and costly means.” – Chris Blattman + “War is the violence that doesn’t make sense” – Chris Blattman + War is a breakdown of reason – everybody loses something from war and there’s usually a better and more efficient solution * War is rare and history shows we’re pretty successful at avoiding it–but that’s not how history is taught + We overemphasize the anecdotal and don’t look at the objective data–usually to fuel the warmonger narrative, which is driven by one of the five root causes of war (below) * Both Russia and Ukraine have incentives to bluff, which can result in many short-term conflicts but also affect long-term compromise/appeasement + “If you bluff and lose, it’s not because you miscalculated. You made an optimal choice given the uncertainty of the situation to take a gamble–that’s a wiser thing for you to do than to not bluff.” – Chris Blattman + This call and bluff dynamic could end up with Russia getting what they originally were asking for from Ukraine–but only after incurring unnecessary costs * “There’s a reason for every war and a war for every reason” – The five roots of war: + Unchecked leaders: leaders do not bear the majority of costs or have a private incentive (Chris believes this is the fundamental cause of most violence in the world) + Uncertainty: when the opposing group’s strength or intentions are ambiguous, war seems like an appropriate risk to combat uncertainty + Commitment problems: some circumstances give one side an irresistible incentive to risk war + Intangible incentives: intransigence for ideologies, choosing war rather than changing your view + Misperceptions: miscalculating the complexity of the enemy or yourselves

Read the full notes @ podcastnotes.org

Chris Blattman is a professor at the University of Chicago studying the causes and consequences of violence and war. Please support this podcast by checking out our sponsors: – Truebill: https://truebill.com/lex – Mizzen+Main: https://mizzenandmain.com and use code LEX to get $35 off – Grammarly: https://grammarly.com/lex to get 20% off premium – Indeed: https://indeed.com/lex to get $75 credit – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Chris’s Twitter: https://twitter.com/cblatts Chris’s Website: https://chrisblattman.com Why We Fight (book): https://amzn.to/3702fjb PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips:

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No Stupid Questions

Podcast Notes Key Takeaways * Poor nutrition is a 90% demand problem and only a 10% supply problem + Citing data fromFood Deserts and the Causes of Nutritional Inequality + Just being more accessible didn’t change purchase behavior for food, it requires high levels of education to counter deeply embedded cultural and demographic nutrition habits * Healthy food has an uphill narrative battle against unhealthy food + More expensive, less ready to prepare, low-shelf life, less caloric, and the list goes on * “If there is a way to increase demand for healthy food, without making people feel bad, that’s going to be the trick”– Angela Duckworth + It worked with smoking cigarettes, why can’t it work with food? + Implementing taxes on unhealthy food and subsidizing healthy food could help ignite a much needed social and cultural change * What other societal topics miscalculate supply and demand problems? + Bipartisan politicians: everyone complains there are none, but no one wants their politicians to compromise + Sleep: people always say they don’t get enough sleep, but it’s not for lack of time–they choose to do other things

Read the full notes @ podcastnotes.org

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Knowledge Project

Podcast Notes Key Takeaways * Check out The Knowledge Project Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Leading neuroscientist and Stanford University School of Medicine professor Dr. Andrew Huberman goes in-depth on how small behaviors can make a huge impact on your health. Dr. Huberman offers essential insights into how light affects your sleep and your energy levels, which supplements actually work, tips to control bad impulses, exercises to slow the aging process, and so much more. Dr. Huberman has made numerous significant contributions to the fields of brain development, brain function and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills and cognitive functioning. Huberman is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award in 2017, given to the scientist making the most significant discoveries in the study of vision. His lab’s most recent work focuses on the influence of vision and respiration on human performance and brain states, such as fear and courage. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Drive with Dr. Peter Attia

Podcast Notes Key Takeaways * Fat oxidation, carbohydrates, and lactate are connected – lactate is the byproduct of glucose utilization * The capacity to transport lactate through high-intensity exercise is trainable * Well-trained & elite athletes have an amazing ability to oxidize lactate in mitochondria – but everyone gets to a point where the effort can’t be sustained, the difference is how long it takes you to get there * People with metabolic syndrome who are characterized by having poor mitochondrial function cannot do an exercise oxidized with lactate because they produce lactate but can’t oxidize the lactate (their slow-twitch muscles don’t have mitochondria to use fat so rely on glucose) * A reasonable measure of how zone 2 should feel: you can carry out a full conversation, maybe not as comfortably as if you weren’t exercising, but still without much strain – the other person will know you’re exercising but you are understandable * Zone 2 is necessary for mitochondrial health, high intensity is necessary for glycolytic efficiency (which you can improve in just a matter of months if consistent) * Ideal training protocol: 4 days of zone 2 training lasting 60-90 minutes + 1 day of anaerobic/high-intensity effort * High-intensity suggestion: keep it simple – 4 minutes high effort, near heart rate max + 4 minutes of recovery x 4-5 cycles * PSA: to be considered a zone 2 workout, you need to spend the entire duration in zone 2 for the benefit – not just an average of zone 2 oscillating faster and slower periods

Read the full notes @ podcastnotes.org

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Episode Description:

Iñigo San-Millán is an internationally renowned applied physiologist and a previous guest on The Drive. His research and clinical work focuses on exercise-related metabolism, metabolic health, diabetes, cancer metabolism, nutrition, sports performance, and critical care. In this episode, Iñigo describes how his work with Tour de France winner Tadej Pogačar has provided insights into the amazing potential of elite athletes from a performance and metabolic perspective. He speaks specifically about lactate levels, fat oxidation, how carbohydrates in food can affect our lactate and how equal lactate outputs between an athlete and a metabolically unhealthy individual can mean different things. Next, he discusses how Zone 2 training boosts mitochondrial function and impacts longevity. He explains the different metrics for assessing one’s Zone 2 threshold and describes the optimal dose, frequency, duration, and type of exercise for Zone 2. Additionally, he offers his thoughts on how to incorporate high intensity training (Zone 5) to optimize health, as well as the potential of metformin and NAD to boost mitochondrial health. Finally, he discusses insights he’s gathered from studying the mitochondria of long COVID patients in the ICU.

We discuss:

The amazing potential of cyclist Tadej Pogačar [3:00];
Metrics for assessing athletic performance in cyclists and how that impacts race strategy [8:30];
The impact of performance-enhancing drugs and the potential for transparency into athletes’ data during competition [17:00];
Tadej Pogačar’s race strategy and mindset at the Tour de France [24:00];
Defining Zone 2, fat oxidation, and how they are measured [26:45];
Using fat and carbohydrate utilization to calculate mitochondrial function and metabolic flexibility [35:45];
Lactate levels and fat oxidation as it relates to Zone 2 exercise [40:00];
How moderately active individuals should train to improve metabolic function and maximize mitochondrial performance [51:45];
Bioenergetics of the cell and what is different in elite athletes [57:30];
How the level of carbohydrate in the diet affects fuel utilization and power output during exercise [1:08:30];
Glutamine as a source for making glycogen—insights from studying the altered metabolism of ICU patients [1:15:00];
How exercise mobilizes glucose transporters—an important factor in diabetic patients [1:21:00];
Metrics for finding Zone 2 threshold—lactate, heart rate, and more [1:25:00];
Optimal Zone 2 training: dose, frequency, duration, and type of exercise [1:41:15];
How to incorporate high intensity training (Zone 5) to increase VO2 max and optimize fitness [1:51:15];
Compounding benefits of Zone 2 exercise and how we can improve metabolic health into old age [2:01:45];
The effects of metformin, NAD, and supplements on mitochondrial function [2:05:15];
The role of lactate and exercise in cancer [2:13:30];
How assessing metabolic parameters in long COVID patients provides insights into this disease [2:19:00];
The advantages of using cellular surrogates of metabolism instead of VO2 max for prescribing exercise [2:25:45];
Metabolomics reveals how cellular metabolism is altered in sedentary individuals [2:33:45];
Cellular changes in the metabolism of people with diabetes and metabolic syndrome [2:39:15]; and
More.

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Huberman Lab

Podcast Notes Key Takeaways * Training frequency is important for every adaptation you are seeking * In general: strive to work all joints through all ranges of motions throughout the week * The different methods of exercise aren’t about what’s good or bad or right or wrong, but what adaptation do you want? * Hypertrophy training & anaerobic training give you the most physiological adaptations across the most categories * The driver of strength is intensity but the driver of hypertrophy is volume * Soreness is not a barometer of an effective or good workout! You want to feel the muscle group worked but should hover around a soreness of 3 out of 10 * Intentionality in exercise matters: are you doing enough to check the box or are you focusing on contracting your muscle groups? * You’re better off cutting your workout short and hitting a focused 30 minutes than going through the motions for 60 minutes * Breathing properly during & after exercise is critical for telling your body you’re safe: (1) maintain a breath-hold during the lowering/eccentric most dangerous part of the movement & exhale on the concentric portion; (2) try physiologic sigh for 2-5 minutes post-workout and/or between strenuous bouts (double inhale through the nose followed by long exhale through mouth) * The interference effect has recently been debated but overblown – zone 2 cardio in and of itself will not blunt strength or hypertrophy – what matters more is your calorie supply and the type of cardio you’re doing; running (constant eccentric pounding) will have a greater consequence than bike riding * The interference effect is not something most of us need to worry about when comparing the benefit of well-roundedness for overall physiologic health * Sample weekly schedule for endurance: do something once a week that gets you to max heart rate (roughly 220-age) x 4-8 bouts; 150-180 minutes zone 2 training; strength & hypertrophy training supplement * Training protocols should be based on your points of failure – where are you weak and need work? * Speed, power, strength training tips: pick 3-5 exercises, 3-5 reps, 3-5 sets, take 3-5 minutes rest between, train 3-5 days per week – (85% 1RM for strength; 40-70% 1RM for power) * Hypertrophy target: a minimum of 10 working sets, per muscle group, per week, 5-30 reps per set * Endurance training isn’t just about how long you can work, it’s about maintaining joint integrity and allowing muscles to not fatigue when you need them to engage heavy or fast (even standing up) * “You did not get hurt deadlifting because deadlifts are dangerous. You only get hurt deadlifting because you either got in a bad position – you got in a bad position because you either started in a bad position or you ended up in a bad position. You did too much volume, too much intensity, or too much complexity.” – Dr. Andy Galpin * Foundation for proper fluid intake per day = bodyweight/2 (in ounces) * Galpin equation for fluid replenishment during exercise or demanding activity: start exercise hydrated with electrolytes (not just water) then every 15 minutes consume (in ounces) your body weight (in pounds) / 30 * Be judicious in determining whether you’re pushing yourself for adaptation (i.e., pushing stress and not worried about recovery) – or optimization which is the opposite and requires balance

Read the full notes @ podcastnotes.org

My guest is Dr. Andy Galpin, Professor of Kinesiology at California State University, Fullerton, and one of the foremost experts in the world on the science and application of methods to increase strength, hypertrophy and endurance performance. We discuss fundamental principles of strength and hypertrophy training and building endurance, the mechanisms underlying them and we review specific protocols to optimize training and recovery. We also discuss hydration, sleep, nutrition, supplements, and mental tools that can be leveraged to accelerate adaptations leading to enhanced strength, muscle growth and/or endurance.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

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See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

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https://www.patreon.com/andrewhuberman

Supplements from Thorne

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Dr. Andy Galpin Links

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Published Work

Absolute Rest

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Dr. Andy Galpin, Strength & Endurance Training

(00:03:08) The Brain-Body Contract

(00:03:55) AG1 (Athletic Greens), Thesis, InsideTracker

(00:08:20) Adaptations of Exercise, Progressive Overload

(00:14:40) Modifiable Variables, One-Rep Max, Muscle Soreness

(00:27:30) Modifiable Variables of Strength Training, Supersets

(00:43:50) How to Select Training Frequency: Strength vs. Hypertrophy

(00:58:45) Hypertrophy Training, Repetition Ranges, Blood Flow Restriction

(01:08:50) Tools: Protocols for Strength Training, the 3 by 5 Concept

(01:10:48) Mind-Muscle Connection

(01:16:16) Mental Awareness

(01:27:57) Breathing Tools for Resistance Training & Post-Training

(01:37:25) Endurance Training & Combining with Strength

(01:51:20) Tools: Protocols for Endurance Training

(02:08:15) Muscular Endurance, Fast vs. Slow Twitch Muscle

(02:16:35) Hydration & the Galpin Equation, Sodium, Fasting

(02:35:57) Cold Exposure & Training

(02:43:15) Heat Exposure & Training

(02:53:47) Recovery

(03:04:02) Tool: Sodium Bicarbonate

(03:17:26) Tool: Creatine Monohydrate

(03:20:08) Absolute Rest

(03:29:08) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Art of Manliness

A lot of people feel like they've seen and done everything there is to see and do in their local area. They're bored of their daily routine, and contemplate going off on some grand adventure in a exotic locale.

My guest would say that you don't actually have to wait until your next big trip nor go far afield to mix things up, and that adventure can be found right where you are, in your ordinary routines, the everyday landscape of your life, and even DIY projects, if you decide to approach them in a different way.

His name is Beau Miles and he's an Australian filmmaker who documents his own small-scale adventures on YouTube, as well as the author of The Backyard Adventurer. Today on the show, Beau shares his experiments in proving anything can be infused with the challenge, intrigue, and fun which mark adventure, if you add in some intentional risk, difficulty, and simple what-the-heck quirkiness. He tells us about some of the close-to-home adventures he's executed, including walking and kayaking his 90-kilometer commute to work, reconnecting an old, long closed-down rail line by running its often hidden, overgrown path with a shovel in his hand, and making a paddle with scavenged wood. We then talk about how he created a gastronomical adventure for himself by eating his body weight in beans, and even turned tackling his to-do list into an adventure by pairing the crossing off of its entries with running a marathon in 24 hours. Along the way, Beau shares how backyard adventures help you better get to know your local area, how he deals with the police who sometimes check in on what he's up to, and how the next time you get some odd idea, you ought to just go for it, mate.

Resources Related to the Podcast Beau's films/adventures mentioned in the show: + Walking to Work + Paddling to Work + Junk Paddle + Human Bean + Run the Line + Mile an Hour * AoM Article: My 8-Week Microadventure Challenge * AoM Podcast #120: Microadventures With Alastair Humphreys * AoM Podcast #560: The Magic of Walking * Tortilla Flat* by John Steinbeck

Connect With Beau Miles* Beau's Website * Beau on YouTube * Beau on Instagram

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Beginner's Mind ✓

Claim

Podcast Notes Key Takeaways * Check out Beginner’s Mind Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Did you know that almost 90% of all product ideas fail in clinical trials? The most obvious reason that a clinical trial fails is lack of efficacy.

Surprising to me was that lack of efficacy doesn't seem to be the main reason why clinical trials fail in the first place. Other factors are at play, and most of them are manageable risks when the right team is at work.

In this episode, we talk about:

Strategic considerations for setting up a clinical trial
Inhouse vs Outsourced Clinical Study Management
Why do some clinical trials fail?
Steps to getting your clinical trial back on track
Future trends of clinical trials
and much more

Who is the expert in the show?Heike Schön is the Managing Director and Co-Founder of Lumis International GmbH and Lumis Life Science Consulting GmbH.

She has more than 25 years of experience in leadership positions in international clinical research and drug development.

📞 Book a meeting here: Link

Youtube: https://youtu.be/r0qphO8Qs3o **Shownotes @ Podcastnotes: tbd

Timestamps:**(00:00) Intro
(02:25) Who Is Heike Schön, Lumis International and Lumis Consulting?
(04:20) Topics in the Episode
(04:30) Kick-Off
(05:00) Background to Lumis International and Heike Schön
(10:20) When is the Right Time to Start with the Planning of a Clinical Trial?
(12:10) The Role of a Sponsor of a Clinical Trial
(14:30) Who is Responsible for the Clinical Trial as a Sponsor?
(16:55) When Should a Company Start to Implement Clinical Trial Management in the Organisation?
(18:30) Funding Requirements for Clinical Trials
(20:00) The Reality of Inhouse and Outhouse Clinical Trial Management
(22:15) What to Think About When Planning Oversight Management
(25:00) Relationship and Culture Management in Clinical Trials
(27:25) Budget and Ressource Requirement for Clinical Trials
(28: 45) 3 Steps to a Successful Clinical Trial
(30:40) The 3 Main Reasons Why Clinical Trials Fail
(33:30) Considerations for Patient Enrollment as a Key Success Factor for Clinical Trials
(37:30) … and when enrolment fails, what are the steps to rescue the trial?
(42:45) Do Inhouse Studies Require Rescue?
(44:30) How to Rescue a Clinical Trial
(48:30) Root Cause Analysis as a Starting Point to Rescue a Trial
(52:25) Preventive Measures to Avoid Failure Early on
(53:30) How Important is Leadership in a Clinical Trial?
(56:30) The 3 Main Reasons to Stop a Clinical Trial – The Point of no Return
(59:00) How are the Cost Calculated for Rescue Study Management?
(01:00:15) Planning of a Clinical Trial – A Key Aspect of a Successful Trial
(01:02:15) How to Plan Realistic Timelines and Numbers
(01:07:15) The Role of Feasibility Studies in Clinical Trials
(01:09:30) How Clinical Trial Management Evolved in the last 30 years
(01:11:15) Upcoming Trends in Clinical Trial Management
(01:13:15) Decentralized Clinical Trials
(01:15:00) Artificial Intelligence And Big Data in Clinical Trial Management
(01:17:55) The Digital Twin
(01:19:15) The Human Factor and Leadership in Clinical Trial Management
(01:21:10) The Patient in Clinical Trials
(01:22:55) Planning and its contribution to clinical trial success
(01:26:55) Summary of What to Do When Clinical Trials Fail
(01:28:35) When is the Right Time to Add a Rescue Team to the Clinical Trial?
(01:31:00) A Risk Management Plan for Clinical Trials
(01:32:00) How to Cont

Support the show (https://lsg2g.substack.com/subscribe?)

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Twenty Minute VC

Podcast Notes Key Takeaways * Check out the 20VC Episode Page & Podcast Notes

Read the full notes @ podcastnotes.org

David Friedberg is Founder and CEO of The Production Board (TPB), a holding company established to solve the most fundamental problems that affect our planet, by reimagining global systems of production. Prior to founding The Production Board, David founded The Climate Corporation, a 10-year journey that culminated in their $930M acquisition by Monsanto. If that was not enough, David is the Founder and Chairman at Metromile and also sits on the board of Soylent, Clara Foods, Tillable, Cana Technologies and more.

In Today’s Episode with David Friedberg You Will Learn: 1.) Origins:

How David made his way into the world of startups and technology from academia and physics?
What were David's biggest takeaways from scaling The Climate Corp to $930M exit to Monsanto?
How did the exit put pressure on David for all future companies he builds? How does he manage that?

2.) The Macro: Venture + The Economy

How does David foresee the impending rate hikes? What impact will this have on venture and the economy?
What segment of the market will be first to be hit? Why is growth investing last to be hit? How does early stage play out in this very new environment?
How will we see the velocity of capital deployment change in this new period? What does David believe are some of the crucial flaws of the venture model?
How does David reflect on his own price sensitivity? What lessons has he learned from deals he has done or missed that have changed his perspective?

3.) David Frankel: The Business Builder

What is David's rubrik for business value creation? How has this changed with time?
How mentally plastic does one have to be around the time it takes to see margins, unit economics etc change from negative to positive?
How does David and the team approach building new companies at TPB? Where do they find the founding teams? How do they incentivise them?
How does TPB approach continuous funding for the companies they create? What milestones need to be hit? How do they assess them?
How does David approach liquidity with regards to exits for the companies they create? Why does their holding company structure mean they have different incentives to VCs?

4.) David Friedberg: Father and Husband

How does David reflect on his own relationship to money today? How has it changed over time?
What have been David's biggest realisations on what provides him true happiness?
How did having children change his operating mentality? What does being a great father mean to David?

Item’s Mentioned In Today’s Episode with David Friedberg David’s Favourite Book: Zen Mind, Beginner's Mind

Zen Mind, Beginner's Mind: Informal Talks on Zen Meditation and Practice (Shambhala Library)

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The Danny Miranda Podcast

Podcast Notes Key Takeaways * Check out The Danny Miranda Podcast Episode Page & Show Notes

Read the full notes @ podcastnotes.org

(0:00) Intro

(2:15) Ice hockey experience

(5:15) What made Dr. Proctor keep going?

(6:00) Meeting Olympian hockey players

(9:25) Getting recognized in public

(11:53) Almost an astronaut

(15:07) Why did Dr. Proctor’s friend suggest she apply to be an astronaut?

(16:29) How do you cultivate curiosity for new technologies?

(18:00) How did Dr. Proctor’s dad help her

(20:07) Why your self-talk is so important

(22:23) Going to Mars?

(24:30) What challenges do we face settling on Mars?

(26:16) Civilians going to space

(28:05) What should we expect on Mars?

(30:40) “Learn to be more forgiving to yourself”

(33:28) Talking to Michelle Obama

(36:58) Starship Earth

(40:49) Where does Dr. Proctor feel accepted?

(41:52) Seeker poem

(44:28) NFTs and saying yes to early technology

(50:39) Exploring the inner world

(55:49) Jack of all opportunities, master of life experience

(56:50) Nickname “Leo”

(1:00:40) Meeting Elon Musk

(1:04:16) Gryffindor

(1:06:37) Is Inspiration4 a family?

(1:08:47) Connecting with Dr. Proctor

Dr. Sian Proctor is an American geology professor, science communicator, and commercial astronaut. She was launched into Earth orbit, on September 15, 2021, as the pilot of the Crew Dragon space capsule.

I originally came across Dr. Proctor when she starred in the Netflix special Countdown: Inspiration4 Mission to Space. In this conversation, we spoke about settling on Mars, getting recognized, and her many talents + interests.

Dr. Proctor's Twitter – https://twitter.com/DrSianProctor

Space2Inspire – https://www.amazon.com/Space2inspire-Inspiration-Dr-Sian-Proctor/dp/1733765417

Continue the conversation with me... 🎙 Podcast: https://podfollow.com/1532160275

🐣 Twitter: https://twitter.com/heydannymiranda

📸 Instagram: https://instagram.com/heydannymiranda

🕺 TikTok: https://tiktok.com/@heydannymiranda

🚨 Newsletter: https://dannymiranda.com/tuesday-treasure/

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Huberman Lab

Podcast Notes Key Takeaways * Any time you eat something sweet, that food substance causes neuropod cells in the gut to send parallel signals to the brain which activates dopamine and tells us to seek out and eat more sweet foods * Glucose is the preferred source of fuel for the brain and nervous system (in a typical diet regimen): mechanisms hardwired into us that make it difficult not to eat the sweet food or give in to the craving * Getting sweet things into the body has a bit to do with the taste but just as much to do with the nutritive component for the nervous system those sweet things carry * Fruits have been improperly demonized; the fructose content of fruit is quite low – it’s the high fructose corn syrups and sugary beverages we really want to avoid * It’s no accident that “hidden sugars” are hidden with salt or other flavors – it’s done so people will ingest more of a particular food regardless of how sweet that food tastes * The case for eliminating or reducing sugary drinks: if glucose is replaced with fructose in sugary drinks, there’s a decrease in type 2 diabetes and metabolic syndrome associated with high fructose corn syrup, even if the same number of calories is ingested * Sleep! Quality sleep is critical to form a firm foundation of proper metabolism and to help combat sugar cravings * Home remedies to offset glucose spikes: (1) a few tablespoons of lemon juice or lime juice – or (2) a little pure cinnamon – before, during, or after a large meal or sugar intake can blunt glucose response

Read the full notes @ podcastnotes.org

I explain how to blunt sugar cravings through fundamental knowledge of how sugar is sensed, metabolized, and utilized within the body. I explain how sugar is processed through the digestive tract and nervous system and how both the taste and nutritive components of sugar can lead to specific appetite changes and cravings. I discuss the connection between sugar, dopamine, and cravings and outline many tools to curb sugar cravings, specifically craving highly processed refined sugars.

Thank you to our sponsors

Thesis: https://takethesis.com/huberman

AG1 (Athletic Greens): https://athleticgreens.com/huberman

InsideTracker: https://insidetracker.com/huberman

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Thorne

https://www.thorne.com/u/huberman

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Sugar & Physiology

(00:02:25) The Brain-Body Contract

(00:03:13) Thesis, AG1 (Athletic Greens), InsideTracker

(00:07:40) Sugar & the Brain

(00:10:06) Appetite & Hormones: Ghrelin & Insulin

(00:14:17) Glucose & Brain Function

(00:24:19) Glucose & Physical Activity

(00:26:16) Fructose vs. Glucose

(00:32:41) When to Eat High-Sugar Foods?

(00:35:01) Sugar’s Taste vs. Nutritive Pathways, Sugar Cravings

(00:41:46) Tool: Sugar & the Dopamine, Pleasure – Pain Dichotomy

(00:48:43) Subconscious Sugar Circuits, Hidden Sugars in Food

(00:58:03) Glucose Metabolism in the Brain

(01:03:00) Tool: Glycemic Index, Blunting Sugar Cravings

(01:12:08) Sugary Drinks, Highly Refined Sugars

(01:14:33) Artificial Sweeteners

(01:22:36) ADHD, Omega-3s

(01:30:18) Tools: Reduce Sugar Cravings with EPA Omega-3s & Glutamine

(01:35:15) Tool: Blunt Sugar Peaks & Craving with Lemon Juice

(01:43:09) Tool: Reduce Sugar Cravings & Spikes with Cinnamon

(01:45:10) Berberine, Sustained Low Blood Glucose Levels

(01:51:24) Tool: Sleep & Sugar Cravings

(01:56:33) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Patreon, Instagram, Twitter, Thorne, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Kyle Kingsbury Podcast

Chad Johnson is a permaculture maestro. He’s studied under Sepp Holzer and cut his teeth in the North of Minnesota where he practices a permaculture/food forest model of working with the land. He’s the man we’re working with to help work with the land in Lockhardt. We’ll run it back, but here’s an incredible intro to him and the work that he does.

Connect with Chad:

Website: www.keystoneintelligence.org

Show Notes:

"Desert or Paradise" Sepp Holzer
"Sepp Holzer's Permaculture"
The Biggest Little Farm - Amazon
Living 4D Ep 97 - Dr. Ibrahim Karim: BioGeometry: Profound Healing Through Ancient Wisdom and Modern Science
biogeometry.ca/home
Agriculture - Rudolph Steiner
Regenerative Agriculture - Richard Perkins

Sponsors:

Qualia Mind is hands down the most balanced neurotropic I have in my arsenal right now. Head over to neurohacker.com for a month’s supply currently @ 50% off. Punch in code “KKP” for an additional 15% off everything.
PaleoValley Some of the best and highest quality goodies I personally get into are available at paleovalley.com, punch in code “KYLE” at checkout and get 15% off everything!
Super Speciosa is the absolute best Kratom I’ve worked with head over to getsuperleaf.com/kkp and punch in “KKP” at checkout for 20% off everything in store!
Organifi Go to organifi.com/kkp to get my favorite way to easily get the most potent blend of high vibration fruits, veggies and other goodies into your diet! Click that link and use code “KKP” at checkout for 20% off your order!

Connect with Kyle:

Fit For Service Academy App: Fit For Service Academy

Instagram: @livingwiththekingsburys

Youtube: Kyle Kingbury Podcast

Kyles website: www.kingsbu.com

Zion Node: https://getzion.com/ > Enter PubKey

PubKey: YXykqSCaSTZNMy2pZI2o6RNIN0YDtHgvarhy18dFOU25_asVcBSiu691v4zM6bkLDHtzQB2PJC4AJA7BF19HVWUi7fmQ

Like and subscribe to the podcast anywhere you can find podcasts. Leave a 5-star review and let me know what resonates or doesn’t.

Sepp Holzer's Permaculture: A Practical Guide to Small-Scale, Integrative Farming and Gardening

Agriculture: Spiritual Foundations for the Renewal of Agriculture

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Rich Roll Podcast

Podcast Notes Key Takeaways * Where safe, try behavioral tools first: though pharmaceutical intervention will change your chemical balance, it won’t help you change your behaviors and train the tools you need * The field of science is shifting toward seriously studying previously “fringe” topics acupuncture, breathwork, effects of temperature regulation, the brain-gut connection * Cyclic physiologic sighs seem to have the greatest effect on the greatest number of parameters – to try: two inhales through the nose followed by long exhale through the mouth for 5 minutes * Clinical hypnosis grabs both states of arousal – a high degree of focus and a high degree of relaxation in a way that enhances neuroplasticity * Guided clinical hypnosis has been successful in the treatment of trauma, ADHD, and eating disorders * “Much of how we are gauged in terms of who we are is on our behavior and how calm people perceive us to be or how stressed people perceive us to be in certain contexts.” – Dr. Andrew Huberman * To really optimize your output, anchor your biology to our natural 24-hour cycle: get sunlight in your eyes the first hour of waking (or bright overhead light if not accessible) and maintain some exposure in the early part of the day, avoid bright light in the early evening, avoid napping if it interferes with nighttime sleep, maintain a regular sleep/wake schedule * Key is doing self-exploration to find ideal timing of meals, light exposure, and sleep that align with circadian rhythm – start by manipulating light exposure because that’s the most powerful driver of the other pieces * Major stimuli for setting brain states: light, temperature, movement, food, social interactions

Read the full notes @ podcastnotes.org

How does behavior affect your biology? What does neuroscience say about hypnosis, breath work, and meditation? Are behavioral tools more powerful than pharmaceuticals in changing your state and focus?

Today we dig into these big questions and more with neuroplasticity overlord Dr. Andrew Huberman, back for a second, highly anticipated return to the show.

Given that Dr. Huberman’s first appearance on the podcast (RRP #533) has amassed over 10 million views on YouTube alone, chances are you’re already familiar with this tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine, where he runs The Huberman Lab, which studies neural regeneration, neuroplasticity, and brain states such as stress, focus, fear, and optimal performance.

Subsequent to our first podcast in January of 2021, Andrew launched The Huberman Lab Podcast, which has quickly become a sensation. Within a year of launch, it has ascended to one of the top, most listened to podcasts in the world.

Today we pick up where we last left off, diving deep into a wide array of fascinating topics brimming with actionable takeaways, including:

the emerging field of mind-body neuroscience;
the neuroscience of ADHD, focus, hypnosis, and processing trauma;
how to leverage light, temperature, breath, and sleep to better control your biology;
several behavioral tools for achieving optimal performance states;
how to cultivate learning states and the power of something called gap effects; and
many other fascinating topics

To read more, click here. You can also watch it all go down on YouTube. And as always, the podcast streams wild and free on Apple Podcasts and Spotify.

Andrew is a passionate man with an incredible facility for communicating complex scientific topics in a uniquely compelling and understanding way.

For those keen on understanding how to better control your mind, neurochemistry, and all told biology—consider this episode appointment listening.

SCIENCE!

Peace + Plants,

See acast.com/privacy for privacy and opt-out information.

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Knowledge Project

Podcast Notes Key Takeaways * Don’t force sleep, it’s dangerous to stay awake in bed for long periods of time + “You’d never sit at the dinner table waiting to get hungry, so why would you lie in bed waiting to get sleepy?” – Matthew Walker + Pavlov’s Classical Conditioning: your brain will begin to bond a negative association with your bed and being awake + Target a sleep efficiency of 85%-90% (time spent in bed asleep) * The harder you try to sleep, the harder it becomes + Don’t count sheep, take yourself on a long mental journey. Take your mind off of itself. * “The snooze button is the perennial expression of the human frustration of chronic lingering sleep debt”– Matthew Walker + Experiment: If you regularly set an alarm clock, would you wake up at that same relative time without the alarm clock? + If no, you’re probably operating in a sleep deficit * Alcohol and Caffeine before bed reduce your body’s ability to benefit from sleep + Alcohol is the opposite of a sleep aid, it is a sedative and sedation is not sleep + Try to cut off caffeine consumption 10 hours before bed + Continue reading for specific biological responses * Matthew mentions some methods for combatting insomnia and sleeping better + Cognitive Behavioral Therapy for Insomnia (CBT-I) + Sleep Restriction and Behavioral Therapy for Insomnia + How to Determine Your Chronotype and Ideal Sleep Schedule

Read the full notes @ podcastnotes.org

Renowned sleep scientist Matthew Walker discusses everything you need to know about what a better night’s sleep can do for your life, and how to prioritize and perfect the way you sleep. Walker breaks down how to identify when you need more sleep, how to deal with insomnia, the best devices to track your sleep, and some unconventional sleep hygiene tips, including why it’s never a good idea to count sheep.
Walker is a Professor of Neuroscience and Psychology at the University of California-Berkeley, and is also the founder and director of the Center for Human Sleep Science. He has published over 100 scientific research studies on the impact of sleep on human brain function, and he is the author of the 2017 book, Why We Sleep: Unlocking the Power of Sleep and Dreams. -- Want even more? Members get early access, hand-edited transcripts, member-only episodes, and so much more. Learn more here: https://fs.blog/membership/

Every Sunday our Brain Food newsletter shares timeless insights and ideas that you can use at work and home. Add it to your inbox: https://fs.blog/newsletter/

Follow Shane on Twitter at: https://twitter.com/ShaneAParrish

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Jocko Unravelling ✓

Claim

Podcast Notes Key Takeaways * Check out The Unraveling Podcast Episode Page & Show Notes * Disclaimer: There is no doubt that Putin is the aggressor and is doing terrible things to the Ukrainian people. However, there is a long interwoven history of US misadventures abroad that shouldn’t be forgotten.

Read the full notes @ podcastnotes.org

Jocko and Darryl welcome special guest Scott Horton. Scott is the director of the Libertarian Institute, and the senior editor of antiwar.com. He's also an author of books such as Fool's Errand: Time to End the War in Afghanistan, and Enough Already: Time to End the War on Terror.

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Huberman Lab

Podcast Notes Key Takeaways * Conscious and unconscious salt intake and sensing modulates cravings for sugar, water, and other things * Sodium is the way your neurons communicate – having enough salt in the body allows the brain and nervous system to function * Sodium and water work together in the body: thirst is not just a way to bring fluid into our body – it’s an internal signal telling us to balance salt level * “If you’re craving salt, you probably need it.” – Dr. Andrew Huberman * It’s helpful to have a formula and not just consume salt and water-based on craving because your body tends to adapt to certain levels of salt over time so it doesn’t provide a consistent indicator * The notion that a high salt diet is bad for you is confounded by the fact that high salt diets are usually rich in processed foods and a poor balance of carbohydrates to fat * There’s a direct relationship between the stress system (glucocorticoid system) and the salt craving system * If you’re feeling anxious, slightly increasing sodium intake can stabilize blood pressure and ability to lean into stressors and challenges * Galpin equation for fluid replenishment during exercise or cognitively demanding activity: start exercise hydrated with electrolytes (not just water) then every 15 minutes consume (in ounces) your body weight (in pounds) / 30 * Rule of thumb if you fast or follow time-restricted eating: caffeine is a diuretic so for every ounce of caffeine, drink 1.5x as much water with a touch of sodium * Very generalized recommended mineral intake, barring health conditions: 3.2-4.8g of sodium, 4g of potassium * It’s critical that you know your blood pressure to make informed decisions about salt and fluid intake – salt needs will vary accordingly

Read the full notes @ podcastnotes.org

I discuss the role of salt (sodium) in the nervous system and the key role that it plays in mental performance, physical performance and health. I explain how the brain senses salt levels in our body and how that relates to our feelings of thirst. I cover the physiology of the renal system and the hormones that control sodium and water balance in our body. I also explore how salt interacts with stress and our immune systems and its crucial role in neuron function. Additionally, I examine research findings suggesting that some individuals might benefit from increased intake of sodium and other electrolytes (magnesium and potassium) to enhance mental performance, lessen anxiety, and offset dizziness. Yet, other people may need less sodium. I discuss how you can determine your optimal sodium intake and why sodium intake levels need to be uniquely tailored to an individual’s lifestyle. Finally, I explain how salt creates ‘hidden’ sugars in many processed foods and the problems that can create. Throughout the episode, I explain peer-reviewed findings outlining salt’s essential role in overall health and describe general recommendations and tools anyone can use to find their optimal salt balance and thereby enhance their brain and body’s performance.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

LMNT: https://drinklmnt.com/huberman

InsideTracker: https://insidetracker.com/huberman

Celebrate Pi Day (3.14) with InsideTracker - 31% off through 3.17 with code HUBERMANPIDAY

See Andrew Huberman Live: The Brain Body Contract

Tuesday, May 17th: Seattle, WA

Wednesday, May 18th: Portland, OR

https://hubermanlab.com/tour

Our Patreon page

https://www.patreon.com/andrewhuberman

Supplements from Thorne

https://www.thorne.com/u/huberman

For the full show notes, visit hubermanlab.com.

Timestamps

(00:00:00) Role of Salt

(00:02:18) The Brain-Body Contract

(00:02:57) Neuropod Cells, Artificial Sweeteners & ‘Hidden’ Cravings

(00:10:57) AG1 (Athletic Greens), LMNT, InsideTracker

(00:15:06) Salt Regulation

(00:17:13) How the Brain Senses Salt

(00:24:15) Salt & Thirst

(00:29:27) Blood Pressure & Thirst

(00:33:47) Kidneys & Urine Regulation

(00:39:08) Vasopressin: Roles in Libido & Urination

(00:45:46) How Much Salt Do You Need?

(00:56:45) Should You Increase Your Salt Intake?

(01:02:19) Tools: Determining Your Individual Salt Intake

(01:14:02) Iodine, Sea Salt

(01:17:13) Salt: Roles in Stress & Anxiety

(01:24:20) Other Electrolytes: Magnesium & Potassium

(01:27:57) Tools: Effects of Low-carbohydrate Diets & Caffeine

(01:32:28) General Recommendations for Salt Intake

(01:36:34) Perception of Salt & Sugar Taste, Processed Foods

(01:47:13) Role of Sodium in Neuronal Function, Action Potentials

(01:53:13) Dehydration

(01:55:36) What Salt Intake is Best for You?

(02:00:58) Zero-Cost Support, YouTube Feedback, Spotify, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Sway

Keith Rabois minted his wealth with Elon Musk, Peter Thiel and other members of the so-called “PayPal Mafia.” Now, though, he’s moved to Miami and become one of the city’s biggest hype men. He believes Florida — which has already seen an influx of tech bros, venture capital investments and cryptocurrency plays during the pandemic — offers a better home to tech than California can, largely because of the politics. He tells Kara Swisher: “The mayor of Miami, the governor of Florida treat citizens like customers. ‘What can we offer you? How can we help?’ That’s their goal, and that’s how they frame everything.”

In this conversation, Kara presses Rabois whether tech’s doubling down on Florida is all just about escaping high taxes. They also discuss whether venture capital is what investment banking was in the 2000s. And they catch up on the news, from stock fall-offs in big tech to why Peter Thiel will be stepping down from Meta’s board.

You can find transcripts (posted midday) and more information for all episodes at nytimes.com/sway, and you can find Kara on Twitter @karaswisher.

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Doctor's Farmacy with Mark Hyman, MD

Podcast Notes Key Takeaways * “[Glyphosate] jams up your biochemistry. It’s like throwing sand in an engine.”– Mark Hyman, MD + Glyphosate is a weed killer that is exposed to 70% of all crops * Glyphosate can directly impact your microbiome and increase your chances of the leaky gut–which leads to much greater systemic health problems + Leaky gut: the barrier of the gut is broken and the bacteria and food proteins from the gut leak into your bloodstream–creating a systemic and destructive response + The gut and microbiome is linked to countless chronic conditions: heart disease, auto-immune disorders, allergic disorders, autism, mental health conditions, eczema, and more + 52% of all children are diagnosed with a chronic condition before they are 16, compared to 1.2% in the 1960s before these chemicals were introduced + “We can really start to map out the extinction of mankind” – Dr. Zach Bush * The consumer market is having a larger impact on chemical-use regulation than the government ever has + Consumers are refusing to use products with certain chemicals + This changes the dynamics of regulation–once you divert one company away from chemical use, that company will pressure the government to make industry-wide regulations so they are not at a competitive disadvantage

Read the full notes @ podcastnotes.org

This episode is brought to you by Athletic Greens, Cozy Earth, and Eight Sleep.

Glyphosate is a popular pesticide that has a big downside—it’s destroying our health. It damages our good gut bacteria and may lead to leaky gut. Glyphosate also depletes glutathione, our master antioxidant and a cornerstone of our biology, and it dramatically impacts our sulfur, methylation, and detoxification pathways that have many essential roles for our health. And not only is glyphosate harming human health and the health of our future generations, it’s also destroying our ecosystems.

In today’s episode, I talk with Dr. Stephanie Seneff, Ken Cook, and Dr. Zach Bush about why it’s important to be aware of the effects of glyphosate and make choices that reduce our exposure as much as possible.

Stephanie Seneff is a Senior Research Scientist at MIT's Computer Science and Artificial Intelligence Laboratory in Cambridge, Massachusetts. She has a bachelor's degree from MIT in Biology with a minor in Food and Nutrition Science, and a master’s degree, an engineer’s degree, and a PhD degree, all from MIT, in Electrical Engineering and Computer Science. Her recent interests have focused on the role of toxic chemicals and micronutrient deficiencies in health and disease, with a special emphasis on the pervasive herbicide, glyphosate, and the mineral, sulfur. She is the author of Toxic Legacy: How the Weedkiller Glyphosate Is Destroying Our Health and the Environment.

Ken Cook is president and co-founder of the Environmental Working Group, a non-profit, non-partisan organization dedicated to protecting human health and the environment. He is widely recognized as one of the environmental community’s most prominent and influential critics of industrial agriculture and the nation’s broken approach to protecting families and children from toxic substances.

Dr. Zach Bush is a physician specializing in internal medicine, endocrinology, and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems. Dr. Bush founded Seraphic Group and the non-profit Farmer’s Footprint to develop root-cause solutions for human and ecological health. His passion for education reaches across many disciplines, including topics such as the role of soil and water ecosystems in human genomics, immunity, and gut-brain health.

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The Investing City Podcast

In this conversation we cover:

Yaron's investment philosophy
why he is bullish on KKR
an overview of the private equity landscape
and much more!
Thank you so much for listening, we really appreciate you.
If you have found this valuable, please consider leaving us a review as it will help more people find it! Thanks you're awesome!

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Again, we really appreciate that you would take the time to listen. Hope it was valuable. Let us know if you have any questions!

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Lifespan with Dr. David Sinclair ✓

Claim

Podcast Notes Key Takeaways * Our medical model of “wait until you get sick then go to the doctor” really won’t get you where you want to go – the insurance system in the U.S. won’t cover testing unless you’re sick * You can’t impact what you don’t measure! Be proactive about measuring and keeping track of what’s happening in your body through bloodwork and helpful wearables * Technology isn’t waiting for the laws: it’s a matter of when not if – we need data security and privacy protection laws in place, including the right to delete your data, before the use of wearables is rampant * Wearables and sensors will eventually collect thousands of data points per second and ultimately contribute to “lengthening our lives another decade beyond what we’re able to do with changes to lifestyle” – according to Dr. David Sinclair * The key is really to take action based on the information you’re getting from the wearables and sensors * Supplementation is particularly important for people on a specialized diet – you need to be vigilant about measuring bloodwork to make sure you’re doing what’s best for your body * David Sinclair’s 5 biomarkers worth measuring: (1) glucose; (2) heart function (3) inflammation as measured by, c-reactive protein (CRP), tumor necrosis factor (TNF) alpha, cortisol; (4) lactate; (5) blood oxygen * “This is the kind of life I want for everybody, that we don’t have to worry about getting cancer in our 50s and 60s and having a heart attack in our 70s. We should be able to live to our 70s, 80s, 90s and beyond in a healthy way, contributing to society, contributing to the community, educating our kids…” – Dr. David Sinclair * Take responsibility for yourself, and do it for your kids and grandkids’ sake: eat the right way, fast, get exercise, give your body a little stress, supplement as needed, monitor your health proactively

Read the full notes @ podcastnotes.org

In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In addition to discussing the utility of wearable sensors and biological age measurements, they highlight innovative research aimed at reversing biological age. The societal effects of therapies that successfully extend healthspan and/or lifespan are also considered.

Thank you to our sponsors:

Levels - https://levels.link/sinclair
Athletic Greens - https://athleticgreens.com/sinclair
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Our Patreon page: https://www.patreon.com/davidsinclair

Lifespan book: https://amzn.to/3sUqurT

Dr. David Sinclair Social:

Instagram
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Facebook

Matthew LaPlante's Social:

Twitter

To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.

Timestamps:

(00:00:00) Introducing Episode Eight: The Future of Anti-aging Medicine

(00:03:49) Thanking the Sponsors

(00:06:48) Modern Healthcare, Disease Detection, and Circulating DNA

(00:11:30) Wearable Monitors: A Dashboard for your Body

(00:20:31) Types of Health Sensors

(00:24:20) Big Data, Privacy, and Criminal Investigation

(00:30:16) Cutting-edge Testing and Biological Age

(00:36:40) Using Personalized Data to Inform your Diet

(00:41:48) Optimizing Exercise and Activity-mimetics

(00:45:02) Resetting the Aging Clock

(00:53:45) Repeatable Age Reversal and Safety

(00:56:11) Longer Life, Population Size, and Economics

(01:00:18) Skillbatical

(01:03:06) Putting in the Work for Longevity

(01:04:56) Thanking the Podcast Team and Wrapping Up Season One

(01:08:27) Options for Subscription and Support

For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.

Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Title Card Photo Credit: Mike Blabac

Special thanks to our research assistants, Adiv Johnson & Sarah Ryan.

Lifespan: Why We Age―and Why We Don't Have To

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * “Any geopolitical conflict from now on is guaranteed to have some cyber element to it”– Nicole Perlroth + The colonial pipeline, among other breaches of infrastructure, just recently got disclosed as China-backed intrusions (CISA & FBI report) + Uighur ‘watering hole’ attack – visiting an informational website about Uighur’s automatically dropped an iOS zero-day exploit onto your phone. “The Uighurs are China’s test kitchen for surveillance.”– Nicole Perlroth + It has already begun, continue reading for more examples * ‘Software eats the world‘ is a dangerous and “dumb” narrative for critical infrastructure + Just because we can hook all of our systems up to the internet, doesn’t mean we should + The United States infrastructure is very vulnerable to digital threats – 80% or more of America’s critical infrastructure is owned and operated by the private sector with limited cybersecurity standards or legislative oversight * “The one rule is like fight club, nobody talks about fight club. Nobody talks about the zero-day market on both sides…When you’re operating in the dark like that, it’s really easy to put aside your morals.”– Nicole Perlroth + The current hacking environment promotes malicious action and disincentives proactive defense–we need to reestablish motivations among a new cohort of developers

Read the full notes @ podcastnotes.org

Nicole Perlroth is a cybersecurity journalist and author. Please support this podcast by checking out our sponsors: – Linode: https://linode.com/lex to get $100 free credit – InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off – Onnit: https://lexfridman.com/onnit to get up to 10% off – ROKA: https://roka.com/ and use code LEX to get 20% off your first order – Indeed: https://indeed.com/lex to get $75 credit EPISODE LINKS: Nicole’s Twitter: https://twitter.com/nicoleperlroth Nicole’s Website: https://nytimes.com/by/nicole-perlroth Nicole’s Book: https://amzn.to/3sOQjrs PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: –

This Is How They Tell Me the World Ends: The Cyberweapons Arms Race

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Lifespan with Dr. David Sinclair ✓

Claim

Podcast Notes Key Takeaways * The paradox of living longer: our brain ages slower than the rest of our body but because modern medicine has helped us live longer, more people are living with cognitive decline, Alzheimer’s and dementia

Read the full notes @ podcastnotes.org

In this episode of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante dissect the topic of brain aging. They explore evidence suggesting that the brain ages more slowly than other parts of the body and highlight how cognitive function is impacted by aging. Different interventions aimed at preserving brain health are also discussed, including a plant-based diet, exercise, metformin, NAD boosters, and sufficient sleep.

Thank you to our sponsors:

Athletic Greens - https://athleticgreens.com/sinclair
Levels - https://levels.link/sinclair
InsideTracker - https://insidetracker.com/sinclair

Our Patreon page: https://www.patreon.com/davidsinclair

Lifespan book: https://amzn.to/3sUqurT

Dr. David Sinclair Social:

Instagram
Twitter
Facebook

Matthew LaPlante's Social:

Twitter

To stay up to date with David's work to democratize biological age testing and insights, visit tallyhealth.com.

Timestamps:

(00:00:00) Introducing Episode Seven: Aging of the Brain

(00:04:39) Thanking the Sponsors

(00:07:38) Ex-differentiation as a Driver of Aging

(00:09:22) The Brain Ages Slowly

(00:14:17) Cognitive Function and Plasticity

(00:17:44) Three Longevity Pathways: mTOR, AMPK, and Sirtuins

(00:23:26) Plant-based Diets and B-vitamins

(00:28:32) Homocysteine, Plaque, and Vasculature

(00:32:35) Fatty Acids

(00:35:48) Physical Activity

(00:39:14) Metformin

(00:46:02) NAD Boosters

(00:50:33) Increasing Blood Flor

(00:53:20) Sleep

(00:58:02) Overall Message: Keep your Brain Healthy

(00:58:50) Next Week’s Episode and the Future of Medicine

(01:01:21) Options for Subscription for Support

For the full show notes, including the peer-reviewed studies, visit the Lifespan podcast website.

Please note that Lifespan with Dr. David Sinclair is distinct from Dr. Sinclair's teaching and research roles at Harvard Medical School. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Lifespan with Dr. David Sinclair podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.

Title Card Photo Credit: Mike Blabac

Special thanks to our research assistants, Adiv Johnson & Sarah Ryan.

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Sway

Podcast Notes Key Takeaways * NFTs are digital proof of ownership and are still in their nascent stage. * The market is definitely a bubble and most art will go to zero * Beeple intends to portray the weirdness of tech and its unintended consequences

Read the full notes @ podcastnotes.org

From Snoop Dogg to Melania Trump, it seems like everyone has gotten into the NFT craze in the last year, with billions of dollars worth of sales made in 2021. NFTs may be colloquial now, but the craze really picked up almost a year ago, when an artist named Michael Winkelmann (also known as Beeple) sold his work, “EVERYDAYS: THE FIRST 5000 DAYS,” for a whopping $69 million — the third-highest auction price involving a living artist, after Jeff Koons and David Hockney.

So this week, Kara is revisiting her March 2021 conversation with Beeple. They talk about whether his virtual collage, which stitches together 5,000 images (including lactating humanoid breasts and Buzz Lightyear with a bloodied chain saw) is actually worth $69 million, how he grapples with the environmental impact of crypto minting, and how NFTs will change how we buy and flaunt digital ownership.

You can find transcripts (posted midday) and more information for all episodes at nytimes.com/sway, and you can find Kara on Twitter @karaswisher.

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Starting Greatness with Mike Maples

Podcast Notes Key Takeaways * Check out Starting Greatness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Tim Westergren maxed out 11 credit cards, racked up hundreds of thousands of dollars in debt, and was rejected 348 times for a second round of funding for his revolutionary idea for a music streaming platform. But like any true artist, Westergren remained committed to his vision of creating an aesthetically more beautiful future with Pandora, and now the company boasts more than 6 million monthly subscribers. Mike Maples, Jr of FLOODGATE interviews Westergren to discuss the company’s humble beginnings, why it took an act of Congress to keep the company alive, and why both men believe the best founders are artists who can sell their vision.

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Econtalk

What did author and Washington Post columnist Tamar Haspel learn from her quest to eat at least one thing she'd grown, caught, or killed every day? For starters, that just-caught fish always tastes better (unless you've caught a false albacore). That all it takes to build a coop is the will and the right power tools, and that when it comes to homegrown produce, you've got none until you've got way too much. But most of all, she tells EconTalk's Russ Roberts in talking about her book To Boldly Grow, she learned that figuring stuff out to solve problems is more delicious than the most decadent of desserts.

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Huberman Lab

Podcast Notes Key Takeaways * “Our body is shaping the decisions that our brain is making and we’re not aware of it, at all.” – Dr. Andrew Huberman * What you do, eat, think, and feel influences your microbiome * Some microbiota make enzymes locally to digest food, others make neurochemicals that impact brain function and mood * Our experience with and desire for certain foods involves how the food tastes, texture, and subconscious processing of taste in our gut which signal certain neuromodulators * The gut communicates to the brain to change what we think we want or to change our actual behaviors around food * Food and eating is not just about the food and nutrients we need or don’t need, there are subconscious signals and waves of nerve cells always coming from our body and changing the way our brain works * “Our brain is very carefully paying attention to whether the levels of dopamine that are being triggered are within a normal range or whether we gorged ourselves.” – Dr. Andrew Huberman * Creating the correct environment for microbiota to thrive enhances mood and behavior * Parents: the more diversity you can create early, the better chance you’re giving your child at healthy brain-gut signaling and immunity * In general, to create a healthy gut microbiome: eat the right foods, consume pro- and pre-biotics sparingly unless going through periods of high stress, travel, or significant change to diet * Though fasting has a lot of benefits – we don’t know whether it promotes or degrades the microbiome over time but it seems to cause disruption when prolonged * Non-diet related ways to enhance microbiome: get deep sleep, maintain proper social interactions, limit prolonged stress and stressors * To really improve microbiome diversity through diet, consume 4-6 ounces of fermented foods per day – start with 1 and work your way up to avoid gastric distress

Read the full notes @ podcastnotes.org

In this episode, I discuss the profound effect the gut has on the nervous system. I cover the structure and function of the gut-brain axis and the role of the gut microbiome in the brain and overall health. I describe how the gut controls hunger or satiety by affecting neurons in our brain. I also contrast the many pathways by which the gut influences the brain: direct vs. indirect pathways, chemical vs. mechanical, and fast vs. slow signaling. Additionally, I discuss what defines a healthy microbiome and how your lifestyle impacts the gut microbiome, including the effects of stress, fasting, antibiotics, pets, environment, prebiotics and probiotics. I address how different foods shape the gut microbiome, in particular, the emerging data that fermented foods can increase the diversity of healthy gut microbiota. Throughout the episode, I explain peer-reviewed and textbook findings that reveal the critical role of the gut microbiome in supporting mental and physical health and I outline simple tools that anyone can use in order to enhance their gut microbiome health.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

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Social & Website

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Article Links

"The Emerging Biology of Gut-Brain Sensory Transduction"

"Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder"

"Association of Loneliness and Wisdom With Gut Microbial Diversity and Composition: An Exploratory Study"

"Emotional well-being and gut microbiome profiles by enterotype"

"Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis"

"Gut-microbiota-targeted diets modulate human immune status"

"The preference for sugar over sweetener depends on a gut sensor cell"

Book Links

"The 4-Hour Chef: The Simple Path to Cooking Like a Pro, Learning Anything and Living the Good Life"

Timestamps

(00:00:00) Gut Microbiome

(00:03:02) AG1 (Athletic Greens), LMNT, InsideTracker

(00:06:55) Your Gut-Brain Axis

(00:09:44) Gut-Brain Anatomy

(00:15:32) Microbiota vs. Gut Microbiome

(00:20:01) Roles of Gut Microbiome

(00:23:03) Neuropod Cells: (Subconscious) Tasting with Your Stomach

(00:34:13) Ghrelin: Slow Modulation of Your Brain in Hunger

(00:38:02) Glucagon Like Peptide 1; GLP-1

(00:42:22) Tools: ‘Free Will’ & Food Cravings

(00:44:46) Mechanical Cues from Gut to Brain

(00:49:05) Dopamines, Vomiting

(00:52:06) Indirect Signals from Gut Microbiota

(00:59:30) Gut Microbiome “Critical Periods”

(01:03:08) How Gut Health Controls Overall Health

(01:12:25) What is a Healthy Gut Microbiome?

(01:15:00) Tools: Enhance Your Gut Microbiome

(01:23:49) Foods to Enhance Microbiota Diversity; Fermented Foods

(01:37:07) High-Fiber Diets & Inflammation

(01:40:58) Artificial & Non-Caloric Sweeteners

(01:44:27) Structure & Function of Gut-Brain Axis

(01:49:47) Zero-Cost Support, YouTube, Spotify, Apple Reviews, Sponsors, Patreon, Thorne, Instagram, Twitter, Neural Network Newsletter

Title Card Photo Credit: Mike Blabac

Disclaimer

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Starting Greatness with Mike Maples

Podcast Notes Key Takeaways * Check out Starting Greatness Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Your startup will face multiple WFIO moments on the path to greatness...COUNT ON IT. But that doesn’t mean you should let these moments get inside your head. In this lesson of greatness, Mike Maples, Jr of FLOODGATE discusses how every startup team MUST be prepared to take the initiative in the crucible of the WFIO moments they will inevitably face. The bright side? You can use these horrible situations as defining moments to show everyone that your startup is destined to defeat the impossible.

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Artificial Intelligence Podcast

Podcast Notes Key Takeaways * The challenging thing with free speech is that there is a line, the thing that everyone disagrees on is the definition of real harm + “When there is an acute threat, it does make sense from a societal perspective to tolerate less speech” – Mark Zuckerberg + You can’t yell fire in a crowded movie theater–was Covid a fire or not? Mark says yes based on the info he was given. + The blame for improper censorship doesn’t entirely fall on tech companies, blame should also be directed at the institutions of the United States that fail to define harm accurately and honestly * The Social Dilemma vs.What ‘The Social Dilemma’ Gets Wrong + What grabs someone’s attention in the near term is not going to grab it over the long term + Making a user angry isn’t going to retain that user, Facebook doesn’t have an incentive to do this + Subscription product models have pitfalls too, not just ad-based product models + Greater polarization has been found in groups that are least likely to use the internet or social media(link) * The goal of the metaverse is not to build technology for people to interact with; but rather, build technology for people to interact with each other + Spatial audio and eye contact technology are just two features to drastically improve on current video meeting technology, for example + Establishing a presence is the most difficult problem

Read the full notes @ podcastnotes.org

Mark Zuckerberg is CEO of Meta, formerly Facebook. Please support this podcast by checking out our sponsors: – Paperspace: https://gradient.run/lex to get $15 credit – Coinbase: https://coinbase.com/lex to get $5 in free Bitcoin – InsideTracker: https://insidetracker.com/lex and use code Lex25 to get 25% off – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium EPISODE LINKS: Mark’s Facebook: https://facebook.com/zuck Mark’s Instagram: https://instagram.com/zuck Meta AI: https://ai.facebook.com/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT &

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Modern Wisdom

Podcast Notes Key Takeaways * Check out Modern Wisdom Episode Page & Show Notes

Read the full notes @ podcastnotes.org

Daniel Pink is a psychologist, speaker and an author.

Regret is the most common negative emotion humans talk about. It's even the second most common overall emotion which we talk about after love. And yet our relationship with it is pretty terrible. Having no regrets is not only a bad tattoo from the 90's but also a philosophy that robs of us valuable insights from life.

Expect to learn the most common types of regrets people have in life, whether action or inaction is the cause of most suffering, how Daniel suggests we can grow past our regrets, why never looking backward is limiting our growth, how people believe in both free will and things happening for a reason and much more...

Sponsors:

Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/

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Buy The Power Of Regret - https://amzn.to/3I0UUx9

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Get in touch.

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Email: https://chriswillx.com/contact/

The Power of Regret: How Looking Backward Moves Us Forward

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Huberman Lab

Podcast Notes Key Takeaways * Stage hypnosis and self-hypnosis are not the same – stage hypnosis is used to perform and frankly make people look foolish; self-hypnosis is a therapeutic tool used to enter a state of focused attention * We are most hypnotizable between the ages of 6-10 years old; our hypnotizability becomes fixed by our early 20s * About 1/3 of adults are not hypnotizable, 2/3 are hypnotizable – with about 15% extremely hypnotizable * “We underestimate our ability to regulate and change responses – to be cognitively, emotionally, and somatically flexible.” – Dr. David Spiegel * Dissociation is part of the adaptive strategy in trauma; self-hypnosis allows a safe way to activate state-dependent memory and re-confront event and restructure understanding * Self-hypnosis provides an avenue to lean into phobia and trauma and reconnect the events or objects to more positive associations so other centers of the brain are activated * Clinical applications of self-hypnosis: sleep, trauma, pain, phobia, stress, anxiety – and emerging research with grief in cancer patients * EMDR may incorporate some elements of self-hypnosis and suppression of the amygdala which brings people into a calmer state but is likely not as effective as psychotherapy and confronting the issue * Breathing is a bridge between conscious and unconscious states: we can modulate our internal state and produce a change we want to see in our body – this can be leveraged to augment hypnosis

Read the full notes @ podcastnotes.org

My guest is Dr. David Spiegel MD, Associate Chair of Psychiatry & Behavioral Sciences, Director of the Center on Stress and Health and Director of the Center for Integrative Medicine at Stanford University School of Medicine. Dr. Spiegel has more than 40 years of clinical and research experience with hypnosis, stress physiology, and psychotherapy. In this episode, we examine the role of clinical hypnosis for the treatment of trauma, chronic pain, anxiety and more. Dr. Spiegel explains how to determine your level of ‘hypnotizability’ and provides case studies of incredible successes with hypnosis to treat a variety of ailments. We also discuss how breathing, vision and directed mental focus can modulate internal states and enhance performance. Additionally, we discuss how the adoption of self-hypnosis techniques can reduce stress and enhance sleep in anyone. Dr. Spiegel teaches us how hypnosis works at the neural circuit level to enhance cognitive flexibility. Throughout the episode, Dr. Spiegel summarizes key clinical trials and peer-reviewed findings and resources to work with a trained clinical professional or to do guided self-hypnosis.

Thank you to our sponsors

AG1 (Athletic Greens): https://athleticgreens.com/huberman

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Dr. David Spiegel Links

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Support Dr. Spiegel’s Research at Stanford (tax-deductible)

Dr. Spiegel’s Published Work

Email: david@reveri.com

Article Links

Posthypnotic Amnesia in Hypnotizability Assessment: Validation of a New Scoring System for the Hypnotic Induction Profile

Post-traumatic stress disorder and cancer

Association between Anterior Cingulate Neurochemical Concentration and Individual Differences in Hypnotizability

Hypnosis reduces distress and duration of an invasive medical procedure for children

Podcast Notes Playlist: Latest Episodes: Recent Episodes

Podcast Notes

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

cultureapothecary #alexclark #rawmilk #diet #food

The story of how John Wooden won ten national championships on the way to becoming the greatest coach of all time.

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

For the full show notes, transcript, and links to mentioned content, check out the episode page here.

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

577 - David Goggins - This Is How To Master Your Life: https://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: https://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: https://tinyurl.com/3ccn5vkp

How did George Washington shape the future of the United States of America as its first president? In this episode, we examine his presidency, his post-presidency, his death, and his legacy.

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

577 - David Goggins - This Is How To Master Your Life: http://tinyurl.com/43hv6y59

712 - Dr Jordan Peterson - How To Destroy Your Negative Beliefs: http://tinyurl.com/2rtz7avf

700 - Dr Andrew Huberman - The Secret Tools To Hack Your Brain: http://tinyurl.com/3ccn5vkp

For the full show notes, transcript, and links to the best content to learn more, check out the episode page here.

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

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Episode 370: Sam Parr (@TheSamParr) talks to best-selling author, podcaster, bookstore owner, and former marketing director for American Apparel, Ryan Holiday (@RyanHoliday), about how to make money in publishing, creating a masterpiece, and investing in a ghost town.

Episode 390: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk about Eric Langan and his foray into owning strip clubs, why we should boycott Black Friday, three Twitter scenarios, how to fly on a private jet and much, much more.

Episode 394: Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) talk with entrepreneur and Kayak co-founder, Paul English (@englishpaulm) about his latest business ideas, his famous missed investments, how to become a strong recruiter, and why he wants to create Twitter's competitor.

Episode 391: Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) talk about their new favorite AI tool, how to make money from arbitrage, goal setting for 2023, and more.

ListenerLive question #1 – What program do you recommend transitioning from bodybuilding to powerlifting? (46:27)

ListenerLive question #2 - What sort of training and movements would you suggest as I continue this mobility journey in pursuit to get back into playing sports? (55:36)

ListenerLive question #3 - How, if any, can you marry aesthetic, performance, and strength for a dancer? (1:06:47)

ListenerLive question #4 - What is the best way to gain a lot of needed weight while also keeping my physique in check? (1:21:23)

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett

ListenerLive question #1 - Should I be aiming for progressive overload while I’m in a calorie deficit? (49:19)

ListenerLive question #2 - Do you have any advice on how to get my leg strength and mass to catch up to my upper body? (1:00:11)

ListenerLive question #3 - Where should I start in fixing my squat so I'm pain-free? (1:13:05)

Quah question #1 - Incredibly stubborn bicep and tricep growth despite all other muscle groups improving. Should I target volume or intensity, and are giant sets counterproductive or overworking? (58:42)

Quah question #2 - Does the effectiveness of changing phases for hypotrophy say anything about the truth behind “muscle confusion?” (1:07:10)

Quah question #3 - Is it ok to train to failure if I’m only focusing on a muscle group once a week? (1:15:08)

Quah question #4 - Is bodybuilding healthy? (1:21:10)

ListenerLive question #1 – How can I get stronger in the big three lifts to benefit an upcoming powerlifting competition? (1:00:20)

ListenerLive question #2 – What are some ways to correct my knee pain when squatting? (1:12:31)

ListenerLive question #3 – What can I do when my right side doesn’t match the left side? (1:27:29)

ListenerLive question #4 – How would you train in-season versus off-season? (1:36:00)

Quah question #1 – How often should I switch up my lifting exercises for max gains? (1:00:08)

Quah question #2 – Are unilateral movements more beneficial than bilateral movements? (1:06:38)

Quah question #3 – Is vitamin supplementation necessary if you eat a balanced diet? (1:12:27)

Quah question #4 – What are good qualities (or red flags) to look for in a nutritionist? (1:16:49)