MDS Podcast: Recent Episodes
International Parkinson and Movement Disorder Society
Stay up to date on novel, clinically-relevant research findings in Parkinson's disease and other movement disorders. Each episode of the International Parkinson and Movement Disorder Society podcast discusses a relevant development in the field, including highlighted journal articles and interviews with the authors.
In this episode Dr. Tiago Outeiro talks with Dr. Andrew Siderowf about the exciting new results in his most recent publication on alpha-synuclein seed amplification assay.Read the article.
A recent trial showed no benefit of 1mg rasagiline versus placebo on 1-year progression in an early Parkinson's disease cohort. The investigators used a novel method to track disease progression with MRI, apart from usual clinical standards. Dr. David Vaillancourt shares the results of this trial recently published in the Movement Disorders Journal. Read the article.
For this episode of our special series focused on the peer review process, Dr. Kirby speaks with Dr. Tony Lang about how to approach reviewing an original scientific article.
Dr. Tiago Outeiro interviews Dr. Morgane Linard about the recently published article, "Infectious Agents as Potential Drivers of α-Synucleinopathies." Read the Article.
Dr. Di Luca discusses how to approach and review case reports and case series in movement disorders with Prof. Bhatia.
A discussion with Dr. Thaler on the findings and implications of a study on the background of importance of GBA mutations and GCase activity in Parkinson's disease. Read the Article.
This is the third episode of the special series focused on the peer review process. In this episode, Dr. Kirby speaks with Dr. Jon Stoessl about what journal editors are looking for in a good review. He provides practical tips for writing an effective peer review.
For the second episode of the special series focused on the peer review process, Dr. Prasad speaks with Prof. Deuschl about the crucial first part of the peer review process - identifying reviewers, and understanding when a reviewer should accept or decline an invitation to review.
Prof. Lozano shares the results of the phase 2 clinical trial showing safety and feasibility of the staged bilateral MR-guided focus ultrasound thalamotomy in 10 patients. Read the article.
For the first episode of the special series focused on the peer review process, Dr. Di Luca speaks with Dr. Goetz about the importance and most important aspects of a peer review.
For the first episode of the special series focused on the peer review process, Dr. Di Luca speaks with Dr. Goetz about the importance and most important aspects of a peer review.
Dr. Hugo Morales discusses "Neuropsychiatric Features of Punding and Hobbyism in Parkinson’s Disease," by Dr Pedro Barbosa et al., from Movement Disorders Clinical Practice. Read the article.
Dr. Schaefer discusses with Professor Antonio Strafella and Dr. Cecilia Peralta their work from the MDS Neuroimaging Study Group published in Movement Disorders Clinical Practice on a "Pragmatic Approach on Neuroimaging Techniques for the Differential Diagnosis of Parkinsonisms." Read the article
Dr. Hoglinger discusses the article he recently published in the Movement Disorders journal on tau imaging in a cohort of corticobasal syndrome patients, along with amyloid PET and CSF analysis to differentiate the neuropathological entity underlying the clinical manifestations. Read the article
The neurologists Dr. Francesca Morgante and Dr. Nicola Modugno and Cecilia Ferrari, a person with Parkinson's disease, share their experience swimming across the strait of Messina, highlighting the importance of physical activity in PD.
Dr. Matarazzo speaks with Prof. Takahashi about the results of his recent study that shows how this anti-epileptic drug may inhibit the transmission of alpha synuclein in PD. While this was tested in animal models, future clinical trials are warranted to test the effects on PD progression. Read the article
Dr. Schaefer speaks with Dr. Stanley Fahn about the origins of levodopa therapy for Parkinson's disease in the 1960s, how that generated an explosion of interest and research in dopamine's role in movement disorders and beyond, and how it all led to the dawning of the movement disorders field, journal, society, and community that we are all part of today. Read the article
Dr. Matarazzo speaks with Prof. Maja Kojović about the paper awarded as 2021 best review article from the Movement Disorders journal, highlighting the impact on several factors on the variability of movement disorders. Read the article
Dr. Schaefer discusses with Dr. Trenkwalder the 2021 Virtual MDS Congress, her tenure as the MDS president, and her hopes for the future of the MDS.
Dr. Schaefer speaks with Dr. Kanthasamy about RT-QuIC from skin tissues as a potential new biomarker for Parkinson's disease. Read the article
Dr. Schaefer speaks with Dr. Olvera about trending videos of tics and other neurological syndromes on social media. Read the article
Dr. Schaefer speaks with Dr. Camargo about the non-motor and prodromal features of dystonia. Read the article
Dr. Matarazzo interviews Prof. Fisone about the role of autophagy in levodopa-induced dyskinesia. Read the article
Dr. Schaefer discusses with Dr. Garcia Ruiz his recent paper in Movement Disorders Clinical Practice discussing the history and data behind the use of electroconvulsive therapy in Parkinson's disease and other movement disorders. Read the article
Dr. Matarazzo interviews Dr. Ray on a recently published article that demonstrates a relationship between changes in cholinergic nuclei in MRI and future gait disorders in Parkinson's disease. Read the article
Dr. Matarazzo interviews Dr. De Micco on the functional MRI correlates of anxiety in Parkinson's disease, highlighting the main results of the article she recently published on the topic in the Movement Disorders journal.Read the article
Dr. Schaefer speaks with Dr. Pavese about the imaging modalities currently in use and emerging to differentiate parkinsonian syndromes and Parkinson's subtypes, and how imaging helps us to understand, study, and treat these conditions. Read the article
Dr. Wu discusses a newly-described peripherally-induced movement disorder (PIMD), and discusses with Dr. Schaefer the potential pathophysiologies of PIMDs. Read the article
Dr. Matarazzo interviews Dr. Standaert about the review article he recently published on neuroinflammation in Parkinson's disease, including the main evidence of its role on the pathogenesis of the disease and how understanding it better may help us discovering new therapeutic targets. Read the article
Dr. Brit Mollenhauer discusses the recent advances in the use of neurofilament light chain for the diagnosis and follow up of Parkinson's disease and related disorders, highlighting the results of a recent longitudinal study. Read the article
Dr. Marta San Luciano shares the main findings of the recently published article on the impact of non-steroidal anti-inflammatory drugs use on the risk of developing PD in a large LRRK2 mutation carriers cohort. Read the article
In this interview, Prof. Brit Mollenhauer provides insight into how researchers have been coping with the COVID-19 pandemic. Read the article
Dr. Michele Matarazzo interviews Dr. Amy Amara, the first author of the article awarded as "2020 Research Article from Movement Disorders" on the effects of exercise on sleep in Parkinson's disease. Read the article
Dr. Michele Matarazzo interviews Dr. Kazuto Tsukita, the first author of the article awarded as "2020 Review Article from Movement Disorders" on the advances of in-vivo alpha-synuclein detection as a biomarker for Parkinson. Read the article
In this interview, Prof. Deuschl highlights the main results of the EARLYSTIM project, focusing on non-motor outcomes, and especially on the effects of DBS on Social and Occupational Functioning in Parkinson's Disease. Read the article
Preprint articles of scientific results have been thrust into the spotlight due to the desire for rapid results pertaining to COVID-19. Here, we dive into the trend with Movement Disorders’ editor, Dr. Jon Stoessl. Read the article
Dr. Matarazzo interviews Dr. Anette Schrag about the recently published article on late-stage parkinsonism and related neuropsychiatric complications. Why is it important? And are we doing enough to help patients at this stage? Read the article
In this interview the president of the MDS, Prof. Claudia Trenkwalder shares the main changes and strategies that the MDS is implementing to adapt to the COVID-19 pandemic, including the replacement of the International MDS congress with a virtual meeting.
Dr. Matarazzo interviews Prof. Roy Alcalay on the effects that the COVID-19 pandemic is having on the clinical activity and how it is changing the way we see patients. Will telemedicine be an integrating part of our clinical practice?
Dr. Matarazzo interviews Prof. Angelo Antonini on the effect of the COVID-19 pandemic on Parkinson's disease and other movement disorders patients and how to manage them. And also, what is the evidence of a link between COVID-19 and Parkinson's disease? Read the article
In this issue Dr. Sheperjans shares the results of the article published in the March 2020 issue of the Movement Disorders journal on the effect of antibiotic exposure on the risk of developing Parkinson's disease. Read the article
Dr. Schaefer discusses with Dr. Lidstone her recent paper in Movement Disorders Clinical Practice about a novel, multidisciplinary therapeutic intervention for functional movement disorders patients. Read the article
Dr. Dayal discusses with Dr. Matarazzo how adjusting the pulse width of deep brain stimulation could impact Parkinson's disease, highlighting the results of the paper he recently published in the Movement Disorders journal. Read the article
Dr. Schaefer discusses with Dr. Gregory her recent study on neuroimaging changes and fluid biomarkers in Huntington's disease, and how those may be used to better characterize the biological basis for neurodegeneration in this disease Read the article
Dr. Schaefer speaks with Dr. Pavese about the imaging modalities currently in use and emerging to differentiate parkinsonian syndromes and Parkinson's subtypes, and how imaging helps us to understand, study, and treat these conditions. Read the article
As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Respondek about atypical parkinsonisms, focusing on the MDS activities to advance in the knowledge and management of these diseases and facilitate clinical trials.
As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Espay about technology in movement disorders, highlighting recent advances and the goal of the MDS to create a platform that will combine technology-based data and e-diaries.
As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Chaudhuri about news in Parkinson’s disease and Lewy body dementia, including new treatments, scales and other advances in early and late-stage PD. Read the article
As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Ganos about the newly created MDS Tic Disorders and Tourette Syndrome Study Group, and the main news breakthroughs in the field, that have been discussed during the MDS Congress.
As part of the MDS Congress 2019 Special Issue, Dr. Matarazzo interviews Dr. Elble about recent advances in tremor classification, diagnosis and treatment approaches, and about the future plans of the MDS Tremor study group to overcome current challenges for clinicians and researchers.
Dr. Schaefer discusses with Dr. Kamel the role of botulinum toxin in the treatment of refractory upper limb tremor, and his center's tailored approach to provide relief for these patients. Read the article
As part of the MDS Congress 2019 Special Issue, Dr. Schaefer interviews Dr. Strafella about the emerging research in neuroimaging in movement disorders and plans to establish a centralized database for neuroimaging in atypical parkinsonisms.
As part of the MDS Congress 2019 Special Issue, Dr. Schaefer interviews Dr. Jinnah about notable research in dystonia and activities of the MDS Dystonia Study Group.
As part of the MDS Congress 2019 Special Issue, Dr. Schaefer and Dr. Tabrizi discuss the evolving research in disease-modifying therapies for Huntington's Disease, and what may come next. Read the article
As part of the MDS Congress 2019 Special Issue, Dr. Schaefer interviews Dr. Postuma about all of the educational offerings through the MDS, as well as new projects of the MDS Education Committee.
Did you miss the MDS Congress in Nice, or do you just want an overview of highlights from the International Congress as well as a look forward at new ventures? Dr. Schaefer introduces the MDS Congress 2019 special issue, which features interviews with experts in various fields of movement disorders at the MDS Congress 2019. In this first issue, Dr. Schaefer interviews Dr. LaFaver about notable research in functional movement disorders, activities of the MDS Functional Movement Disorders Study Group, and more.
In this interview with Dr. Jabbari we highlight the results of his study on the definition and genetic and neuropathological characteristics of early onset progressive supranuclear palsy. The full study is available on the September 2019 issue of the Movement Disorders journal. Read the article
Dr. Farwa Ali discusses with Dr. Schaefer the results of her study on the use of the MDS criteria for PSP with the MAX rules and their clinical implications, as well as the challenges of the phenotype variability of this disease in clinical practice and research. Read the article
Dr. Bergsland discusses with Dr. Matarazzo the results of the article he recently published in the Movement Disorders journal on longitudinal iron imaging in the substantia nigra in PD and in its different regions. Read the article
Benjamin Deck discusses with Dr. Schaefer the article he recently published in the Movement Disorders Clinical Practice on the patient vs. care partner assessment of cognition in Parkinson's disease. Read the article
Dr. Chang shares the results of 4-year follow-up of MR-guided focused ultrasound thalamotomy in essential tremor. In his article, recently published in the Movement Disorders journal, he analyzes whether the efficacy of this procedure is sustained over time. Read the article
Dr. Ruth Schneider discusses with Dr. Sara Schaefer about the article she recently published in the Movement Disorders Clinical Practice that investigates the outcomes of early vs delayed start of dopaminergic medication in Parkinson's disease. Read the article
Dr. K. Ray Chaudhuri discusses with Dr. Michele Matarazzo his article on the differences between subthalamic nucleus DBS, intrajejunal levodopa and apomorphine infusion in Parkinson's, published in the March 2019 issue of the Movement Disorders journal. Read the article
Dr. Mered Parnes discusses with Dr. Sara Schaefer his article on benign hereditary chorea recently published in the January 2019 issue of the Movement Disorders Clinical Practice. Read the article
Dr. Nikolaos Scarmeas discusses with Dr. Michele Matarazzo the results of his article about the impact of the Mediterranean diet on the risk of Parkinson’s disease, published in the January 2019 issue of the Movement Disorders journal. Read the article
In this introductory podcast, the hosts, Dr. Michele Matarazzo and Dr. Sara Schaefer, introduce themselves and interview the editor-in-chief of the Movement Disorders Journal, Prof. Jose Obeso.
Dr. Brit Mollenhauer discusses the recent advances in the use of neurofilament light chain for the diagnosis and follow up of Parkinson's disease and related disorders, highlighting the results of a recent longitudinal study.
Dr. Matarazzo interviews Dr. Ray on a recently published article that demonstrates a relationship between changes in cholinergic nuclei in MRI and future gait disorders in Parkinson's disease.