A weekly podcast for pharmacists, physicians, physician assistants, and nurse practitioners who are interested in learning more about clinical pharmacology topics. To claim pharmacology CE credit or to get a copy of presentation slides, visit https://ce.mayo.edu/pharmacypodcast. Produced by @MayoMedEd. Hosted by @garrett_schramm.
Damon Alvarez, PharmD, MBA provides insights on statin use in people living with HIV.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Kennedy Concannon, PharmD discusses the use of thiamine in septic shock.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Katie Bye, PharmD shares insights on buprenorphine induction strategies for opioid use disorders.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Brandy Hernandez, PharmD shares nuances on the use of uridine triacetate and glucarpidase in chemotherapy toxicity management
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Taylor Gullickson, PharmD educates on the use of beta-blockers in portal hypertension
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Megan Edwards, PharmD discusses optimal management of acetaminophen overdose.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Micaela Warfield, PharmD shares updates on the timing of anticoagulation following stroke secondary to atrial fibrillation.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Jake Noble, PharmD, MPH reviews management of respiratory syncytial virus in patients undergoing allogeneic hematopoietic stem cell transplant.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Caitlin Schanz, PharmD & Krysta Larson, PharmD review metformin use inpatient and incretin mimetic use perioperatively.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Alex McCarthy, PharmD, MS discusses aminoglycoside induced hearing loss and genetic testing.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Trinkal Patel, PharmD shares insights on compassionate use and investigational medicine.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Krista Olson, PharmD reviews pharmacotherapeutic approaches to latent autoimmune diabetes in adults.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Sherwyn Tenia, PharmD, MBA, BCPS, PMP explores interoperability with a focus on smart infusion pumps.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Nate Johnson, PharmD, BCPS discusses updates in the pharmacologic treatment for psoriasis.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Mark Layden discusses pharmacy quality outcomes, metrics, and the future direction of justifying clinical pharmacy services.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Jenna Jackson we will review mechanisms of resistance, management of multidrug resistant infections, and antimicrobial development.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Matt Neumann, PharmD outlines recommendations to manage patients with penicillin and other antimicrobial allergy labels.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Alyssa Pitterle, PharmD compares rate and rhythm control in the management of atrial fibrillation with a focus on pharmacotherapy.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Lauren Metropulos, PharmD will review seizure prophylaxis in traumatic brain injury.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Natalie Hagy, PharmD, discusses medical use of psychedelics, including legislative and practical considerations for states and hospitals
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Mickenzie Meyers, PharmD shares insights on pharmacotherapeutic approaches to weight loss.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X @MayoMedE
Jordyn Erkel, PharmD reviews the connection between migraines and cardiovascular disease.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on X at @MayoMedE
Taylor Gullickson, PharmD explores the role of brentuximab vedotin in pediatric Hodgkin’s lymphoma.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedE
Kennedy Concannon, PharmD discusses cytomegalovirus prophylaxis in solid organ transplantation.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Micaela Warfield, PharmD evaluates the role of prolonged infusion of beta-lactam antibiotics.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Katie Bye, PharmD provides insights on the management of COPD exacerbations.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Will Carns, PharmD reviews the role of intravenous iron in the treatment of heart failure with reduced ejection fraction.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Julia Branger, PharmD discusses use of buprenorphine in the perioperative period.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Megan Edwards, PharmD shares insights on navigating infection risk with advanced therapies for inflammatory bowel disease.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Brandy Hernandez, PharmD reviews approaches to nutritional need assessment in critical care.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrea Aguayo, PharmD provides insights on statin intolerance and alternative approaches.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kimberly James, PharmD shares developments on respiratory syncytial virus (RSV) prevention in infants.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Krysta Larson, PharmD provides updates on heart failure treatment strategies in transitions of care.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jenna Puttkamer, PharmD shares insights into toxicity management of bispecific t-cell engagers.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Maggie Ruschmeyer, PharmD reviews the evidence in colchicine for secondary prevention of ASCVD.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Brianna Chambers, PharmD describes the landscape for HER-2 low classification in the treatment of breast cancer.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Allie Curran, PharmD reviews blood pressure management strategies in intracerebral hemorrhage.
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You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Caitlin Schanz, PharmD discusses considerations for clozapine-induced myocarditis.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Abdullah Al-Ajmi, PharmD, BCPS reviews approaches to viral reactivation following cancer treatment.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Tanner Melton, PharmD reviews pharmacologic management of post cardiac transplant.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hailey Thompson, PharmD shares SHOCKing updates on the use of corticosteroids in septic shock.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mark Layden, PharmD, MBA shares the place in therapy for hypoxia-inducible factor prolyl hydroxylase inhibitors and other general approaches to anemia management in chronic kidney disease.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Natalie T. Hagy, PharmD shares new antifungal agents in the pipeline, their novel mechanisms of action, and available formulations.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Ming May Zhang, PharmD reviews pharmacokinetic considerations in extracorporeal membrane oxygenation.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hailey Thompson, PharmD, reviews primary literature and shares updates on the role of monoclonal antibody therapies in the treatment of Alzheimer’s Disease.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Christopher Cahoon, PharmD elucidates the literature pertaining to injectable cabotegravir and rilpivirine as HIV therapy options.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Shienna Braga, PharmD examines the literature pertaining to dual pathway inhibition for lower extremity arterial disease.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Caitlin Schanz, PharmD discusses antiphospholipid syndrome, with a focus on data comparing direct oral anticoagulants versus warfarin as anticoagulation strategies in these patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Lauren Stonerock, PharmD describes updates in outpatient management of chronic kidney disease.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Serena Mitaly, PharmD shares strategies for pharmacogenomic research translation to reduce health disparities.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Devon Stonerock, PharmD, Uzo Abajue, PharmD and Divya Khandekar, PharmD describe cytokine release syndrome (CRS), the literature surrounding CRS and options for CRS management.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kelli Herrin, PharmD reviews the pathophysiology of transthyretin amyloidosis cardiomyopathy and provides updates on medication options.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jonathan Leung, PharmD, BCPS, BCPP provides updates on the clozapine REMS program, reviews the therapeutic benefits of clozapine, as well as key adverse events.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes.
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Sarah A. Chase, PharmD reviews the pathophysiology and current treatment strategies for inflammatory bowel disease, defines the clinical application of therapeutic drug monitoring of biologic therapies used in inflammatory bowel disease and discusses biologic therapy optimization based on therapeutic drug monitoring.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle A. Hess, PharmD, BCPS Twitter: @KyleHessPharmD describes the pathophysiology of calcium channel blocker overdose, explains the rationale for use of insulin-euglycemic therapy in calcium channel blocker overdose and identifies differences between the pathophysiology of dihydropyridine overdose and non-dihydropyridine overdose.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Scott A. Soefje, PharmD, MBA, BCOP, FCCP, FHOPA (Twitter: @sasoefje) describes the relationship between value and quality, defines quality and how quality measures will impact healthcare in the coming years, and demonstrates how organizations may use quality measures to improve value.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Benjamin J. Anderson, PharmD, MPH, FASHP and Diana J. Schreier, PharmD, MBA, BCPS recognize the history and regulations for prospective medication order review, describe the technical landscape for verification decision support and explore real-world verification decision support outcomes.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nikitha Yagnala, PharmD and Andy J. Jatis, PharmD, BCPS describe the pathophysiology of hepatorenal syndrome (HRS), describe the pathophysiology of hepatorenal syndrome (HRS) and outline an optimal patient care plan for the management of HRS.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kamryn R. Storm, PharmD (Twitter @KRStorm) outlines the mechanism of toxicity for ethylene glycol, identifies clinical findings of ethylene glycol toxicity and selects treatment regimens for suspected ethylene glycol toxicity.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Ashton C. Praska, PharmD (Twitter @ashpraka) describes tetracycline resistance mechanisms utilized by bacteria, identifies how Omadacycline/Eravacycline can overcome common tetracycline resistance mechanisms and identifies clinical scenarios where Omadacycline/Eravacycline could be considered for use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kristina M. Thurber, PharmD, BCPS recognizes pharmacotherapy for the treatment of obesity and explain mechanisms of action for each class, discusses and compares clinical data and weight loss outcomes for common treatment options, and determines an optimal pharmacologic regimen for the treatment of obesity given patient-specific factors.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jo Ann Leal, PharmD (Twitter @JoJoPharmD) describes the key components of the drug supply chain and the impact of drug shortages, identifies common organizational strategies used to mitigate drug shortages and evaluates recent national efforts to stabilize the drug supply chain.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew (Andy) F. Wiener, PharmD (Twtitter @andywiener) describes the pathogenesis and risk factors of C. diff infection and recurrence, reviews the preferred treatment modalities for prevention of C. diff recurrence and describes the cost-benefit analysis supporting guideline-directed management of C. diff infections.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Seth M. Kriha, PharmD identifies guideline recommended treatment to reduce LDL-C, evaluates landmark clinical trials for novel therapeutic agents indicated for treatment resistant hypercholesterolemia and develops a pharmacologic care plan for a patient with treatment resistant hypercholesterolemia.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Christopher R. Cahoon, PharmD defines the importance of optimizing bone health in patients with bone metastases and lytic lesions, describes preferred bone-targeted therapy for patients with malignancy-associated bone disease and discusses the safety limitations associated with bisphosphonates and RANKL inhibitors.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Shienna A. Braga, PharmD explains the effects of select chemotherapeutic agents on gonadal function and fertility in cancer patients, recognizes the different modalities utilized for fertility preservation in adults and children with cancer and reviews current literature that describes the role of gonadotropin-releasing hormone agonists (GnRHa) in women diagnosed with cancer.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Linda Huang, Pharm.D identifies considerations for use of select provider-recommended supplements, describes literature that helps explain use of select supplements in outpatient treatment plans and discusses patient cases that highlight place in therapy for supplement use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hailey A. Thompson, PharmD identifies the physiologic factors that increase venous thromboembolism risk in trauma patients, outlines current recommendations and their pitfalls for venous thromboembolism prophylaxis in trauma patients and discusses evidence for anti-Xa monitoring for venous thromboembolism prophylaxis with enoxaparin.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Caitlin C. Schanz, PharmD (@Schanz_Caitlin) explains the pharmacological mechanism of steroid use in community-acquired pneumonia treatment, interprets literature assessing use of steroids in management of community-acquired pneumonia and relates efficacy and safety outcomes of steroids in community-acquired pneumonia to a patient case.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Alejandro Del Rio Verduzco, PharmD (Twitter: @Alejandro_DRV) defines the different short-term and long-term toxicities of CAR-T therapy, describes evidence for existing management strategies for late-term CAR-T toxicities and identifies evidence and reports of emerging late-term CAR-T toxicities.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Aleesha Jantzen, PharmD describes social determinants of health that impact management of cardiovascular disease states, recognizes racial/ethnic disparities in management of atrial fibrillation, myocardial infection, hypertension, and heart failure and identifies pharmacist interventions to minimize racial/ethnic disparities in cardiovascular disease state management.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Tanner A. Melton, PharmD (Twitter @TAMeltonRx) reviews factors associated with inter- and intra-patient mycophenolate pharmacokinetic variability, describes current strategies to perform mycophenolate therapeutic drug monitoring and determines an optimal monitoring plan for the treatment of a solid organ transplant recipient.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mark P. Layden, PharmD, MBA (Twitter @Layden_Rx) describes the pathophysiology of sepsis and role of Vitamin C in the critically ill population, identifies the proposed benefits of Vitamin C use in the critically ill patient population and discusses updated literature on the current role of Vitamin C in sepsis.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Natalie T. Hagy, PharmD describes the monoamine and glutaminergic pathway for the treatment of major depressive disorder, recognizes response and remission rates of first line treatment for major depressive disorder and describes the clinical trials for dextromethorphan-bupropion and its impact on the landscape of major depressive disorder.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Lauren R. Stonerock, PharmD (@LStonerockRx) reviews the history of insulin delivery technology and its impact on diabetes management, identifies patient-specific factors associated with successful insulin pump use and discusses current insulin pumps and highlight their specific features.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Chelsea M. Morken, PharmD (@ChelseaMorken) explains the pathophysiology of rheumatoid arthritis (RA), describes the literature regarding cardiovascular risks with Janus-kinase inhibitors and recognizes appropriate initial therapy based on patient specific factors.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Uzoamaka (Uzo) C. Abajue, PharmD (@Uzo_Chi) discusses the manifestations, diagnosis, and classification of chemotherapy induced cardiotoxicity, identifies causative oncologic agents responsible for cardiotoxicities and outlines strategies for cardiotoxicity management due to oncologic agents.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Megan A. Galle, PharmD (@meganciclovir) reviews eculizumab’s mechanism of action and its role in treating antibody mediated rejection following solid organ transplantation, discusses laboratory testing methods available for eculizumab therapeutic drug monitoring and describes the role of therapeutic drug monitoring in eculizumab treatment optimization.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Devon S. Stonerock, PharmD (@DevonStoneRx) describes the underlying pathophysiology driving the development and progression of aplastic anemia, outlines treatment options based on patient specific factors and recognizes key toxicities, drug interactions, and administration considerations for patients receiving immunosuppressive therapy.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Sarah A. Chase, PharmD identifies the most common ESBL-producing bacteria and common ESBL resistance genes, recognizes the use and limitations in using phenotypic and genotypic data to identify potential ESBL-E organisms and discusses clinical trial data and IDSA guidance to assist in the selection of appropriate antimicrobials for the treatment of ESBL-E infections .
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle A. Hess, PharmD (@KyleHessPHarmD) describes the rationale for early use of vasopressors with multiple mechanisms of action in patients with septic shock, reviews the literature examining the early initiation of vasopressin in patients with septic shock and identifies patient characteristics associated with positive response to angiotensin II.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Divya A. Khandekar, PharmD, MS (@pharmdiv) discusses the basic principles of radiation therapy in the treatment of cancer, describes the etiology and pathophysiology of toxicities caused by radiation therapy and identifies which pharmacological treatments for radiation toxicity management are evidence-based.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nikitha Yagnala, PharmD (@nikithayagnala) recognizes the physiologic consequences of sleep disturbances in critically ill patients, discusses the mechanisms of sleep promotion for pharmacologic sleep agents and outlines appropriate utilization of pharmacologic sleep agents in critically ill patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew J. Jatis, PharmD (Twittter:@jatis_rx) Identifies adverse consequences of fluid overload in critically ill patients, summarizes literature assessing the efficacy and safety of fluid stewardship strategies and generates patient-specific plans for fluid management based on available evidence.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jo Ann Leal, PharmD (Twitter: @jojopharmd) describes the implications of various CYP2C19 phenotypes on clopidogrel metabolism and activity, analyzes the available literature evaluating outcomes of clopidogrel versus ticagrelor in ischemic stroke patients based on CYP2C19 metabolizer status and selects a preferred antiplatelet agent and dose for secondary prevention of ischemic stroke given patient specific pharmacogenomic information.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
KaShena L. Kennedy, PharmD (Twitter: @KaShenaKennedy) reviews and identifies the pathophysiology, clinical manifestations, and diagnostic criteria for TA-TMA in pediatric patients, differentiates risk factors associated with TA-TMA and discusses prophylactic treatment in pediatric patients and explores treatment and emerging therapy options of TA-TMA in pediatric patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Aeryana Beaudrie-Nunn, PharmD (Twitter: @ABeaudrieRx) identifies the rationale for antithrombotic therapy following TAVR, reviews the utility of direct oral anticoagulants after TAVR considering recent clinical trial data and defines the patient context where direct oral anticoagulant use following TAVR is most appropriate.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle A. Hess, PharmD (Twitter: @KyleHessPharmD ) describes current guideline recommendations for duration of dual antiplatelet therapy (DAPT) following percutaneous coronary intervention, compares and contrasts strategies for antiplatelet regimens for reduced duration DAPT and selects an appropriate duration of therapy when utilizing shortened DAPT.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nikitha Yagnala, PharmD (Twitter: @NikithaYagnala) describes laboratory tests used to estimate DOAC plasma levels, reviews current literature exploring the association between DOAC plasma levels and clinical outcomes and outlines appropriate utilization and interpretation of DOAC plasma levels in clinical practice.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Divya A. Khandekar, PharmD, MS (Twitter: @pharmdiv) describes the etiology of febrile neutropenia in patients with hematological malignancies, summarizes guideline-based recommendations for antibiotic discontinuation in patients with febrile neutropenia and discusses primary literature supporting early antibiotic discontinuation in patients with febrile neutropenia.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew J. Jatis, PharmD (Twitter: @jatis_rx) reviews the pharmacology and drug characteristics of dalbavancin and oritavancin, describes current literature assessing the safety and efficacy of FDA approved and off-label indications for lipoglycopeptide use in clinical practice and discusses pharmacoeconomic implications of lipoglycopeptide use in clinical practice.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kaylee A. Clark, PharmD describes the basic principles of maintenance therapies after allogeneic HSCT, discusses evidence and guideline recommendations for maintenance therapies after allogeneic HSCT for acute lymphoblastic leukemia and reviews evidence and guideline recommendations for maintenance therapies after allogeneic HSCT for acute myeloid leukemia.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle J. Eickman, PharmD, describe the goals of six sigma methodology and review examples of its application within pharmacy dispensing, reviews DMAIC methodology and describes how lean and six sigma can be used to achieve the same goals of patient safety.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Dimple R. Dhakal, PharmD describes the pharmacodynamics and pharmacokinetics of methadone, identifies and discusses clinical practice guidelines for the safe use of methadone and evaluates evidence for CYP2B6-guided methadone use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Julie L. Cunningham, PharmD, BCPP; M. Zeeshan Rizwan, PharmD, BCPS, BCCCP; Christi A. Jen, PharmD, BCPS, FASHP, FAzPA; and Kristina L. Wescott, PharmD, BCPS identify appropriate non-stigmatizing language related to opioids and addiction in the context of patient care discussions, discuss risks for opioid harms related to individual risks at points of transitions of patient care, review interventions for high-risk opioid patients across transitions of care and identify resources in multiple areas of practice to support patient care for opioid use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah M. Brokmeier, PharmD, describes the pathophysiology behind the pharmacologic targets in ACLS, discusses the role of vasopressin, steroids, and epinephrine in cardiac arrest management, and explains the mechanism and evidence behind administering adjunct agents during ACLS.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Lauren M. Dolly, PharmD, recalls the etiology and pathophysiology of TRD, discusses the role of pharmacogenomics in L-methylfolate for TRD, selects a preferred agent for a patient with TRD with evidence to support its use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Pooja Ojha, PharmD, describes what bias in artificial intelligence entails, discusses implications of bias in artificial intelligence, evaluates mitigation strategies for bias in artificial intelligence.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Molly A. McCord, PharmD, describes pediatric-specific differences in pharmacokinetics as it applies to commonly used immunosuppressants, discusses concerns related to medication formulations, monitoring, and adherence in the pediatric population, reviews pediatric solid organ transplantation pharmacotherapeutic controversies in immunosuppression and infection prevention.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mackenzie L. Bevry, PharmD, identifies the key populations that currently have evidence for improved outcomes with pre-emptive pharmacogenomic testing, describes the difference between clinical and direct-to-consumer pharmacogenomic testing, recognizes some of the currently available pharmacogenomic testing options available to patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Michaela E. Wermers, PharmD, defines therapeutic options and appropriate dosing methods for oral iron replacement, identifies the various intravenous iron therapies and discuss product differences, reviews literature of select disease states in which intravenous iron therapy is utilized.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Stacy A. Bernard, PharmD, BCPS, BCTXP, reviews anti-hypertensive agents and their use in the longitudinal care of a solid organ transplant patient, relates drug-drug interactions between statins and immunosuppressive therapies to dyslipidemia treatment decisions in a solid organ transplant patient, discusses short- and long-term considerations when selecting an anticoagulation regimen for a solid organ transplant patient.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Marissa Z. Powell, PharmD, describes mechanisms of chronic graft versus host disease, recognizes historical approaches to treatment of chronic graft versus host disease, discusses recent updates in chronic graft versus host disease therapy.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hosted by Garrett E. Schramm, Pharm.D., Mayo Clinic Pharmacy Grand Rounds is a weekly podcast for pharmacists, physicians, physician assistants, and nurse practitioners who are interested in learning more about clinical pharmacology topics.
Danielle M. Hess, PharmD, BCPS, describes the mechanism of action of ketamine as it relates to chronic pain relief, evaluates literature depicting the role of ketamine for chronic pain management, defines patient scenarios and/or conditions in which guidelines recommend the potential use and safety precautions of ketamine for chronic pain.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Cassandra J. Schmitt, PharmD, determines risk factors associated with severe COVID-19 disease progression, discusses efficacy and safety outcomes of novel agents for the outpatient treatment of COVID-19, identifies the ideal candidate to receive treatment with oral molnupiravir, nirmatrelvir/ritonavir, or intravenous monoclonal antibodies for mild-to-moderate COVID-19.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jia Yin Townley, PharmD, BCPS, describes the pathophysiology of short bowel syndrome, identifies the medications used to manage short bowel syndrome and recognizes ways to optimize medication regimens for short bowel syndrome patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Sydney E. Schultz, PharmD, @SydneyPharmD identifies presentation, prognostic factors and pathology associated with cancer of unknown primary, reviews historical treatment approaches, and discusses the role for use of molecular profiling to guide treatment.
Twitter: @SydneyPharmD
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Joseph C. Osborne II, PharmD, @JOzempic describes the pharmacology of aducanumab, summarizes the clinical literature and approval process for aducanumab, and discusses stewardship considerations of aducanumab.
Twitter: @JOzempic
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Megan L. Grochowski, PharmD, reviews the incidence of common Crotalidae snake envenomation in the United States, describes the progression of signs and symptoms associated with snakebites, explains the role, use, and administration of antivenom in snakebites, and reviews other interventional therapies utilized in the management and stabilization of snakebites.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Patrick M. Wieruszewski, PharmD, BCCCP, describes the mechanisms of the renin-angiotensin system and its interplay in vasodilatory shock, reviews emerging data surrounding the use of angiotensin II in vasodilatory shock and identifies clinical shock scenarios where angiotensin II may be of most benefit.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mohammad B. Najib, Pharm.D., BCPS, describes the pathophysiology of Neuroleptic Malignant Syndrome (NMS), lists risk factors involved in the disease process, identifies the diagnostic criteria and an overview of the signs and symptoms, and examines management and treatment options.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Rachel J. Johnson, Pharm.D., recalls common symptoms of Guillain-Barré Syndrome, describes the association between COVID-19 vaccines and Guillain-Barré Syndrome, and identifies appropriate treatment for a patient with Guillain-Barré Syndrome.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Aeryana N. Beaudrie-Nunn, Pharm.D. (@ABeaudrieRx), identifies the rationale for immunodulatory therapy in COVID-19, explores clinical trial data regarding the use of Baricitinib in hospitalized patients with COVID-19, and defines the patient context where Baricitinib use is most appropriate.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew J. Jatis, Pharm.D. (@jatis_rx), recognizes the clinical heterogeneity of cardiogenic shock and its impact on clinical outcomes, describes current literature assessing vasopressors and inotropes in the management of cardiogenic shock, and determines an optimal pharmacologic regimen for the treatment of cardiogenic shock given individual patient characteristics.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jennifer M. Nelson, Pharm.D., outlines Center for Disease Control and Prevention (CDC) guidelines for initial care of refugee populations, recognizes unique disease states, genetics, and cultural considerations for the Afghan refugee population, and identifies treatment for unique disease states in the Afghan refugee population.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Robert J. Schroeder, Pharm.D., explains the pharmacological principles of sacubitril/valsartan, recognizes the evidence favoring sacubitril/valsartan in heart failure and describes how to initiate sacubitril/valsartan.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Katelyn (Kate) R. Neverman, Pharm.D., identifies three continuous glucose monitors (CGMs) approved by the FDA, describes the difference between glucose management indicator (GMI) and hemoglobin A1c and discusses how to interpret glycemic data using an Ambulatory Glycemic Profile (AGP) report.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Divya A. Khandekar, Pharm.D., M.S., compares and contrasts the etiologies of heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF), discusses primary literature examining current treatment options for HFpEF and identifies the role of SGLT2 inhibitors in the treatment of HFpEF.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle A. Hess, Pharm.D., recognizes the clinical presentation of beta-lactam induced neurotoxicity, identifies risk factors associated with developing beta-lactam induced neurotoxicity and describes the relationship between drug levels of beta-lactams and development of neurotoxicity.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nikitha Yagnala, Pharm.D., defines iatrogenic withdrawal syndrome in critically ill patients, identifies risk factors for iatrogenic withdrawal syndrome and reviews the current evidence for management of iatrogenic withdrawal syndrome.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jo Ann Leal, Pharm.D., describes the epidemiology of stress ulcers and stress ulcer prophylaxis in select critically ill patients, evaluates the literature that examines the incidence of gastrointestinal bleeding in patients receiving corticosteroids and the outcomes of stress ulcer prophylaxis in patients on dual antiplatelet therapy and analyzes the literature regarding the outcomes of stress ulcer prophylaxis in neurological conditions.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kaylee A. Clark, Pharm.D., reviews the types of hypersensitivity reactions, discusses the pathophysiology and common features of different hypersensitivity reactions to chemotherapeutic agents and describes appropriate prevention and management strategies for hypersensitivity reactions.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Molly A. McCord, Pharm.D., describes the mechanism of action of belatacept, recognizes the role of belatacept in immunosuppression therapy and identifies a patient in whom belatacept therapy may be considered.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Marissa Z. Powell, Pharm.D. (@MarissaP_PharmD), reviews the pathophysiology of nausea and vomiting, describes antiemetic agents and considerations for their use and discusses concern for QT prolongation with use of antiemetics.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Michaela E. Wermers, Pharm.D., describes the epidemiology and pathogenicity of coagulase-negative Staphylococcus (CoNS) species, outlines an evidence-based approach to determine the clinical significance of CoNS isolates and identifies empiric and definitive treatment regimens for pathogenic CoNS.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Sydney E. Schultz, PharmD identifies signs, symptoms, and diagnostic criteria for multiple myeloma, reviews pharmacology of medications used as primary treatment for multiple myeloma and discusses recent literature regarding four-drug regimens.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Cassandra J. Schmitt, PharmD (@cjschmitt2) Identifies the risk stratifications for submassive pulmonary embolism, discusses efficacy and safety outcomes for thrombolytics in submassive pulmonary embolism and selects the ideal candidate to receive thrombolysis for a submassive pulmonary embolism.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah M. Brokmeier, PharmD (@hannahbrokmeier) compares and contrasts the pharmacokinetic and pharmacodynamic properties of heparin and bivalirudin in extracorporeal support, identifies clinical scenarios that favor either heparin or bivalirudin for anticoagulation in ECMO and selects a preferred agent for ECMO when either heparin or bivalirudin are acceptable.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Danielle M. Hess, PharmD (@dhess_09) describes the pathophysiology of opioid-induced constipation (OIC), evaluates literature depicting the safety and efficacy of peripherally-acting mu-opioid receptor antagonists (PAMORAs) for the treatment of OIC and applies the clinical pearls of PAMORAs to patient care.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Audrey J. Umbreit, PharmD, BCACP describes alcohol use disorder (AUD) as a chronic disease, identifies evidence-based medications for treatment of AUD and selects a medication based on individual patient factors to treat AUD.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Brandi N. Smith, PharmD, BCPPS defines necrotizing enterocolitis and late-onset sepsis in the premature neonate and proposed mechanisms of prevention with probiotic use, reviews literature supporting the use of probiotics in premature neonates and recognizes ongoing questions in using probiotics in premature neonates.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kaitlyn J. Bailey, PharmD (@pharmgirl1821) describes the mechanisms of action of select CDK46, PI3K, and PARP inhibitors, reviews the outcomes data related to CDK46, PI3K, and PARP inhibitors for treatment of metastatic breast cancer and discusses toxicity management for CDK46, PI3K, and PARP inhibitors.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mai Uyen Alissa Le, PharmD describes the utility and importance of anticoagulation in ECMO, identifies clinical factors to consider with the use of bivalirudin anticoagulation in ECMO and discusses literature evaluating the use of bivalirudin and its comparison to heparin for anticoagulation in pediatric patients supported on ECMO.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Joseph C. Osborne III, PharmD (@JOzempic) describes the current framework of deprescribing, reviews literature pertinent to deprescribing in the inpatient setting and identifies facilitators, barriers, and future directions for deprescribing.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Natalie A. Haddad, PharmD (@NatalieHaddadRx) describes the epidemiology of multisystem inflammatory syndrome in children (MIS-C), outlines key similarities and differences between MIS-C and other comparable pediatric conditions and discusses current potential therapeutic options for the treatment of MIS-C.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle S. Wamsley, PharmD (@KyleWamsley1) describes the pathophysiology and complications associated with alcohol withdrawal syndrome (AWS), reviews treatment modalities and commonly utilized agents for AWS in the ICU setting and outlines appropriate phenobarbital dosing regiments based on current literature.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Erin D. Wieruszewski, PharmD, BCCCP (@EDWieru) describes the goals of treatment for intracranial hemorrhage, discusses literature examining the use of desmopressin and tranexamic acid for intracranial hemorrhage and identifies appropriate patients to receive treatment with desmopressin or tranexamic acid.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Danielle M. Hess, PharmD (@dhess_09) describes the role of nutrition in cirrhosis and deficiency patterns as it relates to disease severity, evaluates literature depicting the impact of vitamin A, vitamin D, and zinc deficiencies on complications associated with cirrhosis and discusses micronutrient supplementation and monitoring recommendations for the management of cirrhosis.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah M. Brokmeier, PharmD (@hannahbrokmeier) reviews current accepted standards in sedation practices, compares pharmacologic properties of propofol and dexmedetomidine for light sedation and evaluates evidence for choice of optimal sedative agent in light sedation.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Cassandra J. Schmitt, PharmD (@cjschmitt2) identifies guideline recommendations for antiplatelet agents following percutaneous coronary intervention (PCI), reviews the literature examining the safety and efficacy of clopidogrel, ticagrelor, and prasugrel and discusses factors that influence the selection of a P2Y12 agent following PCI.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mary A. Gilmer, PharmD, MHA, BCPS reviews common causes and origins of drug shortages, describes the impacts and implications of drug shortages and discusses strategies and processes for drug shortage management.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Ashley Kate Ragan, PharmD defines actionable proton pump inhibitor (PPI) drug-gene associations, discusses current pharmacogenomic PPI guidelines, including the 2018 Dutch Pharmacogenomic Working Group (DPWG) and 2020 Clinical Pharmacogenetic Implementation Consortium (CPIC) and reviews primary literature depicting CYP2C19 guided PPI dosing.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Alicia E. Mattson, PharmD, BCPS, BCCCP (@AM_EM_PharmD) describes the goals of pharmacotherapy in RSI, discusses literature surrounding medication choice and dose for RSI and selects an appropriate induction and paralytic medication for a patient requiring RSI.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nathan T. Smith, PharmD, BCPS recalls the clinical presentation of gender incongruence, identifies current treatment options for transgender men and women and describes potential cardiovascular risks associated with gender-affirming hormone therapy.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mikaela Hofer, Pharm.D., BSPS, BCCCP (@mikaelamhofer) identifies limitations of current vasopressor agents for the treatment of septic shock, reviews novel vasopressor therapies with a current or potential role in the management of septic shock and describes advancements in the development of biomarkers and pharmacogenomics for the monitoring and individualization of vasopressor treatment.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Allison Golbach, PharmD, BCPS (@AllisonGPharmD) describes epidemiology, pathophysiology, and prognosis of acute myeloid leukemia (AML), reviews literature supporting induction regimens for patients with AML without targetable mutations and discusses how to select between AML induction regimens based on patient-specific factors.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nicole Hlavacek, PharmD (@HlavacekPharmD) recognizes the proposed mechanism of magnesium in different pathologies, recalls dosing and administration rates for magnesium and describes effectiveness of magnesium.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah Poppen, PharmD (@PoppenPharmD) reviews guideline recommendations for management of blood cholesterol, describes the risks and benefits associated with adjunct non-statin therapy and identifies patient-specific characteristics in which PCSK9 inhibitor therapy should be considered.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nicholas Vollmer, PharmD (@VollmerNick) describes the mechanism through which thromboelastography works and how it differs from current assessments of coagulation, identifies patient scenarios where thromboelastography may be of benefit compared to standard of care and discovers barriers of widespread use of thromboelastography.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Yen Tran, PharmD, MBA (@YenTranlt) illustrates the consequences of antibody mediated rejection (AMR) on solid organ transplant recipients, develops a management strategy for AMR and outlines approaches to AMR management.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mikhaila Rice, PharmD, BCPS (@MikhailaPharmD) reviews pathophysiology of gastrointestinal stromal tumors, describes the pharmacology of medications used to treat gastrointestinal stromal tumors and discusses the place in therapy of new treatment options, including ripretinib and avapritinib.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Laurel Lake, PharmD (@laurel_pharmd) outlines the guideline recommendations for duration of antiplatelet therapy in acute coronary syndrome in patients using anticoagulation for atrial fibrillation, reviews recent literature examining antiplatelet therapy in patients with atrial fibrillation and stable coronary artery disease and discusses the balance of risks and benefits of antiplatelet and anticoagulant agents in these patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Dylan Kosaski, PharmD (@Dylan_Kosaski) identifies the purpose of 340B and the impact on health care costs, evaluates the role of 340B contract pharmacies and reviews challenges facing the 340B program and potential consequences.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kellyn Engstrom, PharmD, MPH (@KellynEPharmD) lists three differences between COVID-19 immunization efforts and previous mass immunization strategies, describes challenges in complying with vaccine delivery, storage, and administration processes required by FDA emergency use authorization and summarizes the current state and future directions of COVID-19 mass immunization efforts.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jennifer Adema, PharmD, MBA (@JAdemaPharmD) describes remdesivir’s mechanism of action against SARS-CoV-2, identifies optimal adult patient populations for remdesivir and outlines future directions for remdesivir in COVID-19 treatment.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew Webb, Pharm.D. (@AJWPharm) describes the pharmacokinetic alterations of critical illness and the implications for beta-lactam optimization, recognizes the potential role of beta-lactam therapeutic monitoring in predicting drug effectiveness, and identifies the potential role of beta-lactam therapeutic monitoring in recognizing drug toxicity.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah Brokmeier, Pharm.D. (@hannahbrokmeier) discusses the role of MRAs in patients with ESRD, reviews the literature concerning risks and benefits of MRAs in patients with ESRD, and outlines a potential MRA treatment regimen for a patient with dialysis-dependent ESRD.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kyle Wamsley, Pharm.D. (@KyleWamsley1) discusses current literature surrounding the use of oral antimicrobials in the treatment of infective endocarditis (IE), identifies specific patient populations in whom it may be appropriate to consider oral therapy for the treatment of IE, and outlines oral antimicrobial regimens which may be most appropriate for use in the treatment of IE.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Ashley Otto, Pharm.D., BCPS describes the pathophysiology of non-pulmonary clinical manifestations in cystic fibrosis (CF), reviews guideline recommendations and primary literature to manage non-pulmonary CF complications, and selects appropriate treatment options for patients with non-pulmonary CF complications.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Cassandra Schmitt, Pharm.D. (@cjschmitt2) describes the differences between thrombolytic agents used for the treatment of ischemic stroke, discusses the literature examining the efficacy and safety outcomes of tenecteplase, and identifies the role of tenecteplase in ischemic stroke thrombolysis.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Shannon Piche, Pharm.D., BCPS describes the incidence and clinical manifestation of PICS, reviews literature examining the long term implications of critical illness, and discusses current strategies to address care gaps related to PICS symptom recognition and management.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Allison Golbach, Pharm.D., BCPS (@AllisonGPharmD) reviews the definition, background, and measurement of financial toxicity, discusses the impact of financial toxicity on patients’ clinical outcomes, and identifies methods to help patients make informed decisions about their oncology care.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kellyn Engstrom, Pharm.D., MPH (@KellynEPharmD) reports on current guideline recommendations and gaps in evidence for the treatment of status epilepticus, interprets recent evidence regarding conventional antiepileptic utilization in status epilepticus, and lists three considerations in applying new evidence for status epilepticus treatment into clinical practice.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mikhaila Rice, Pharm.D., BCPS (@MikhailaPharmD) reviews chronic lymphocytic leukemia diagnosis and historical treatment options, describes the pharmacology of Bruton tyrosine kinase inhibitors and venetoclax, and discusses the use of targeted agents as first line therapy for chronic lymphocytic leukemia.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Madison Fazio, Pharm.D. (@madison_fazio) discusses new guideline recommendations for the management of gout, reviews the literature contributing to the new gout recommendations, and recognizes patients that would benefit from newer gout therapies based on guideline recommendations.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Natalie Haddad, Pharm.D. (@NatalieHaddadRx) explains the mechanism of action of midodrine, reviews the current evidence for midodrine and its impact on vasopressor discontinuation and identifies midodrine’s role in therapy for vasopressor discontinuation.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Danielle Hess, Pharm.D. (@dhess_09) describes the potential effects of bariatric surgery on drug pharmacotherapy measures due to altered gastrointestinal anatomy, reviews literature pertaining to warfarin use after bariatric surgery and discusses safety and efficacy of direct-acting oral anticoagulants (DOACs) following bariatric surgery.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nicholas Vollmer, Pharm.D. (@VollmerNick) discusses pharmacological characteristics of tranexamic acid, compares and contrasts primary literature for proposed tranexamic acid indications and identifies pharmacotherapy pearls related to tranexamic acid.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jamie Reed, Pharm.D., BCPS, recalls the pathophysiology of anaphylaxis, differentiates pharmacological options for prevention of anaphylaxis and determines effective acute pharmacological and non-pharmacological management of anaphylaxis.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Sarah Stieven, Pharm.D. reviews the pathophysiology of cystinuria, describes non-pharmacologic and pharmacologic treatment options for cystinuria and reviews potential side effects of pharmacologic options of cystinuria and how to manage
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Joseph Zieminski, Pharm.D. observed in the obese population, discusses pharmacokinetic changes and outcomes data of direct oral anticoagulants (DOACs) in obese patients and selects an appropriate DOAC for use in an obese patient case.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Joseph Osborne II, Pharm.D. (@JOzempic) describes the pharmacology of the gabapentinoids, reviews literature pertaining to perioperative gabapentinoid use for acute pain management and identifies toxicity, misuse, and abuse considerations relating to gabapentinoid use.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jennifer Adema, Pharm.D., M.B.A. (@JAdemaPharmD) identifies different strains of bacteria found in probiotics, discusses target populations for probiotic use and describes the use of probiotics in immunocompromised patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Lindsay Moreland-Head, Pharm.D. (@morelandln) describes the pathophysiology of intravascular versus tissue congestion in Acute Decompensated Heart Failure (ADHF), explains the mechanisms of diuretic resistance in ADHF and why non-inotropic strategies may help augment diuresis and discusses the literature on non-inotropic strategies to decongest patients and overcome loop diuretic resistance in ADHF.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Deann Tims, Pharm.D. will describe the pathiophysiology and complications associate with sickle cell disease, review standard treatment modalities of sickle cell disease and discuss recent literature regarding advancements in sickle cell disease therapy.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Kellyn K. Engstrom, Pharm.D., (@KellynEPHarmD) discusses evidence for efficacy of tramadol for indications of acute or chronic pain in adults, describes major safety and pharmacokinetic considerations for the utilization of tramadol and assesses the current misuse and abuse potential of tramadol.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Nicholas J. Vollmer, Pharm.D., (@VollmerNick) describes the background of penicillin allergies, discusses consequences associated with mislabeled penicillin allergies and identifies strategies institutions can employ to combat the mislabeled penicillin allergies.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Victoria R. Milano, Pharm.D., BCPS, (@VMilanoPharmD) describes the mechanism of immune checkpoint inhibitor and CAR T-cell therapy toxicities, reviews the most common types of toxicities and risk factors associated with immunotherapy treatments and discuss literature and guideline recommendations for the management of immunotherapy toxicities.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Alex B. Wontor, Pharm.D., reviews treatment strategies for the acute symptomatic presentation in thyroid storm, discusses pharmacological treatment for the reduction of thyroid hormone synthesis and describes the long term management of patients that present in thyroid storm to prevent recurrence.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Abby K. Hendricks, Pharm.D., (@HendricksPharmD) identifies risk factors for the development of delirium, discusses literature assessing the use of antipsychotics for delirium in various patient populations and describes treatment options for managing delirious patients.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Catherine DeFino, Pharm.D., (@catherinedefino) describes the epidemiology of childhood cancers, discusses late effects of commonly utilized treatments and reviews management strategies for late effects of childhood cancer.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Jade L. Kutzke, Pharm.D., (@kutzke_jade) summarizes the pathophysiology of acquired thrombotic thrombocytopenic purpura, outlines the current aTTP treatment pathway and identifies caplacizumab’s role in the current treatment approach of aTTP.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mikaela M. Hofer, Pharm.D., (@mikaelamhofer) identifies risk factors associated with postpartum depression, reviews current options for treatment and describes the potential place in therapy for brexanolone in treating postpartum depression.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Casey R. O'Connell, Pharm.D., CPS reviews potential toxicities associated with an acute SSRI overdose, identifies pharmacological interventions used to treat patients with acute SSRI overdose and reviews a patient case pertaining to the management of an acute SSRI overdose.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Hannah Sauer, Pharm.D. describes the challenges in acute medical management of patients with cerebral palsy, lists special considerations for drug therapy in patients with CP and identifies the optimal approach to pain and sedation in patients with CP.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Mikhaila L. Rice, Pharm.D., (@MikhailaPharmD) explains the difference between pre-emptive and prophylaxis strategies for cytomegalovirus infection prevention, selects patients that may benefit from letermovir prophylaxis based on existing literature, and identifies areas of investigational use of letermovir.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Allison P. Golbach, Pharm.D., (@AllisonGPharmD) describes mechanisms of action of medical marijuana in pain relief, reviews the evidence for use of medical marijuana in chronic pain management and medication management considerations for patients using medical marijuana.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Andrew J. Webb, Pharm.D., (@AJWPharm) describes the pathophysiology of myasthenia gravis and how certain antibiotics interact with the disease, outlines available literature investigating the clinical effects and monitoring of antibiotic use in myasthenia gravis, and how to select a safe and effective treatment plan for a patient with myasthenia gravis and a bacterial infection.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Linda Huang, Pharm.D., (@lindaleqi) describes the potential effects of abnormal levels of select vitamins/minerals, discusses recent literature on supplementation of selected vitamins/minerals and the potential drug-nutrient interactions with commonly prescribed medications.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Abby K. Hendricks, Pharm.D., (@HendricksPharmD) reviews strategies to mitigate the risk of gastrointestinal bleeds (GIB) with antithrombotics, shares literature assessing management of antithrombotic therapy after a bleeding event, and designs a treatment plan for appropriate re-initiation of anticoagulants and antiplatelets following GIB.
For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes or the host, Garrett E. Schramm, Pharm.D., @garrett_schramm on Twitter!
You can also connect with the Mayo Clinic’s School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd.
Coming soon! A new podcast from Mayo Clinic Talks Productions:
Mayo Clinic Pharmacy Grand Rounds is a weekly podcast for pharmacists, physicians, physician assistants, and nurse practitioners who are interested in learning more about clinical pharmacology topics. For more information, to claim pharmacology CE credit, or to get a copy of presentation slides, visit ce.mayo.edu/pharmacypodcast.