The EMG Health Podcast: Recent Episodes
EMG-Health
The EMG Health Podcast is an educational and informative podcast which aims to provoke conversations with stakeholders in the healthcare industry. This includes talking about the latest trends and innovations, interviewing thought leaders within the world of healthcare, and regular conversations with physician entrepreneur, Jonathan Sacker.
In this episode, Habib Naqvi explores the current state of race and health inequalities in the UK. Marking the fifth anniversary of the NHS Race and Health Observatory, he reflects on how the conversation around health equity has evolved, discusses the persistent disparities affecting ethnic minority communities, examines the role of healthcare systems and wider social determinants, and addresses the misconceptions that continue to hinder progress towards equitable healthcare.
In this rapid-fire episode, Habib Naqvi answers key questions on health equity, race and the future of the NHS. From the most overlooked determinants of health and common misconceptions about health inequalities to leadership, the achievements of the NHS Race and Health Observatory, and the changes needed to create a fairer healthcare system, this episode offers concise insights for anyone interested in improving health outcomes and advancing equity.
This program is non-promotional and is sponsored by Sanofi and Regeneron Pharmaceuticals, Inc. The content contained in this program was jointly developed by AMJ, the speakers, and Sanofi and Regeneron, and is not eligible for continuing medical education (CME) credits. The speakers were compensated by Sanofi and Regeneron in connection with this program.
COPD trial outcomes are not all equal, yet conventional endpoints can make it difficult to weigh severe events, exacerbations, lung function, and symptom burden within a single clinical picture.
In this AMJ podcast, Sanjay Ramakrishnan and Simon Couillard discuss how win ratio methodology may help capture a broader, more clinically meaningful view of treatment benefit by comparing outcomes across a prespecified hierarchy.
Listen to the full episode to learn:
- Why standard COPD endpoints may not tell the full story
- How win ratio analysis prioritizes outcomes by clinical importance
- What the pooled BOREAS and NOTUS analysis showed
- How this approach could shape future respiratory trial design
Speakers:
- Sanjay Ramakrishnan, Clinical Senior Lecturer, UWA Medical School, Centre for Respiratory Health, The University of Western Australia, Perth, Australia
- Simon Couillard, Professor, Faculty of Medicine and Health, Université de Sherbrooke, Quebec, Canada
In the final episode, Veeru Kasivisvanathan discusses the future of prostate cancer diagnosis, including AI-assisted MRI interpretation, genomic risk prediction, polygenic risk scores, and the opportunities and challenges of population screening. Discover how precision technologies could reshape prostate cancer care over the next decade.
Timestamps:
00:57 – AI and MRI
02:25 – PARADIGM study
02:51 – Large-scale MRI screening
04:56 – Genomics and polygenic risk scores
06:45 – Future optimism of prostate cancer
Veeru Kasivisvanathan joins host Catherine Glass to discuss how MRI-first pathways have transformed prostate cancer diagnosis. Discover how the landmark PRECISION trial reshaped clinical practice, why targeted biopsy improves diagnostic accuracy, and how clinicians are balancing precision with access as MRI becomes the new standard.
Timestamps:
01:05 – Traditional diagnostic approaches
02:55 – PRECISION trial
05:03 – MRI challenges
Veeru Kasivisvanathan joins host Catherine Glass to discuss how MRI-first pathways have transformed prostate cancer diagnosis. Discover how the landmark PRECISION trial reshaped clinical practice, why targeted biopsy improves diagnostic accuracy, and how clinicians are balancing precision with access as MRI becomes the new standard.
01:05 – Traditional diagnostic approaches
02:55 – PRECISION trial
05:03 – MRI challenges
In this rapid-fire episode, Veeru Kasivisvanathan answers key questions on prostate cancer diagnosis, MRI, prostate biopsy, overdiagnosis, AI, and future innovations. From common misconceptions to emerging technologies, this concise episode delivers expert insights into one of the fastest-evolving areas of urology.
In this episode, Anna Caldwell speaks with paediatric allergist and immunologist Zachary Rubin about the rise of medical misinformation, vaccine hesitancy, and the opportunities and challenges of social media in healthcare. They discuss common allergy myths, how clinicians can effectively communicate evidence-based medicine online, and what patients can do to prepare for the 2026 allergy season.
In this episode of Hema Now, Megan Melody speaks about the evolution of CAR-T cell therapy and its impact on lymphoma care. She explores the major advances that have transformed outcomes for patients with relapsed and refractory disease, the unanswered questions shaping current research, and the practical challenges of building successful cellular therapy programmes. The conversation also covers equitable access to treatment, the role of quality standards and accreditation, personalised approaches to CAR-T therapy, and the importance of physician leadership and mentorship in shaping the future of academic haematology.
Timestamps:
00:00 – Introduction
01:13 – Journey into Haematology and Lymphoma
04:19 – Major Advances in CAR-T
06:00 – Unanswered Questions After CAR-T
07:45 – Building Successful Cellular Therapy Programmes
09:06 – Improving Access to CAR-T
12:55 – Evolving Standards in Cellular Therapy
14:16 – Towards Personalised CAR-T Treatment
16:00 – Physician Leadership in Academic Medicine
17:10 – Career Advice for Future Specialists
19:02 – Future Directions in Cellular Therapy
What does the future hold for kidney stone management? In Part 3, David S. Goldfarb explores disparities in care, promising areas of research, and the move towards more personalised approaches to prevention and treatment. He also discusses the impact of climate change on kidney stone risk and shares why he remains optimistic about the future of kidney stone care.
Timestamps:
00:46 – Global warming
02:23 – Emerging research/treatments
03:57 – Asymptomatic kidney stones
04:58 – Broad, empiric approach to treatment
08:29 – Occupation as a risk factor for kidney stones
09:56 – Multidisciplinary care
11:51 – Climate change
13:47 – Calcium and kidney stones
What are the most effective ways to prevent kidney stones from recurring? In Part 2, David S. Goldfarb discusses evidence-based prevention strategies, including dietary counselling, hydration, and the role of pharmacological therapies.
In this episode of Onc Now, Vernon Sondak reflects on the remarkable evolution of melanoma care over the course of his career. He discusses how breakthroughs in surgery, immunotherapy, targeted therapies, and neoadjuvant treatment have transformed outcomes for patients with melanoma and influenced treatment strategies across oncology. The conversation also explores the challenges of paediatric melanoma, the importance of multidisciplinary collaboration, and the future priorities for melanoma research and patient care.
Timestamps:
00:00 – Introduction
01:30 - Melanoma Care Through the Years
06:52 - Sentinel Node Biopsy Impact Today
12:28 - Paediatric Melanoma Care Challenges
21:45 - Collaboration Driving Melanoma Progress
24:57 - Translating Research into Patient Care
31:30 - Exciting Advances in Systemic and Neoadjuvant Therapy
39:06 - Three Wishes for Melanoma Care
What causes kidney stones to form, and why are they becoming increasingly common? In Part 1, David S. Goldfarb explores the physiological mechanisms behind kidney stone disease, the evolving roles of diet, metabolism, and hydration, and the links between kidney stones and broader metabolic conditions, including metabolic syndrome and fatty liver disease. He also reflects on how advances in research have transformed our understanding of risk factors, genetics, and disease prevention.
In this quickfire episode, David S. Goldfarb answers key questions about kidney stone disease, from common misconceptions and risk factors to the roles of genetics, lifestyle, hydration, and prevention. He also discusses changing prevalence trends, and the steps clinicians and patients can take to reduce the burden of this increasingly common condition.
In the final episode, Salvatore Brugaletta explores the future of percutaneous coronary intervention, including AI-assisted decision-making, personalised device selection, and next-generation coronary therapies. Discover how innovation could further improve outcomes for patients with coronary artery disease.
Timestamps:
0:50 – 10 years from now
2:17 – AI
3:47 – Personalised medicine
5:34 – Breakthroughs
7:02 – Salvatore's vision
In Part 2, Salvatore Brugaletta discusses the rise, challenges, and future potential of bioresorbable vascular scaffolds. Learn how advances in material science are improving device performance, which patients may benefit most, and what emerging technologies could redefine coronary intervention.
Timestamps:
0:52 – Bioresorbable scaffold enthusiasm
3:16 – Which patients will benefit?
4:40 – Material Science Advancements
5:48 – Device Innovations
7:02 – Translational Hurdles
In this episode of Hema Now, Jorge Cortes reflects on the remarkable evolution of leukaemia treatment throughout his career, from the transformation of chronic myeloid leukaemia outcomes through targeted therapies to the rapidly changing landscape of acute myeloid leukaemia. He discusses the growing importance of biomarkers and patient-reported outcomes, the value of international collaboration, and how precision medicine is reshaping clinical research. Looking ahead, Cortes shares the developments in immunotherapy and personalised care that he believes could define the next era of leukaemia treatment.
Timestamps:
00:00 – Introduction
01:01 – Inspiration for Haematology and Leukaemia
02:40 – Transforming Chronic Myeloid Leukaemia Care
04:55 – Future Challenges in CML
07:21 – Evolution of AML Treatment
09:50 – Biomarkers and Personalised Leukaemia Care
11:45 – Balancing Outcomes and Quality of Life
14:02 – International Collaboration in CML
16:33 – The Future of Clinical Research
20:03 – Building a Haematology Academic Career
22:04 – Exciting Advances in Leukaemia Research
Salvatore Brugaletta joins host Catherine Glass to explore how intracoronary imaging has transformed modern percutaneous coronary intervention (PCI). From intravascular ultrasound and optical CT to stent optimisation, vascular dysfunction, and AI-enhanced image interpretation, this episode examines the technologies improving procedural precision and patient outcomes.
Timestamps:
0:55 – IVUS and OCT
2:58 – Endothelial recovery
4:55 – Stent failure mechanisms
6:19 – Barriers to adoption
8:18 – Innovations in imaging
In this rapid-fire episode, Salvatore Brugaletta answers key questions on interventional cardiology, coronary imaging, bioresorbable scaffolds, vascular healing, and the future of percutaneous coronary intervention. From AI-assisted procedures to device innovation and career advice, this concise episode offers expert insight into the evolving world of coronary intervention.
In this episode of Onc Now, Mary Disis, Director of the University of Washington's Medicine Cancer Vaccine Institute, Seattle, USA, explores the science and future of cancer vaccines. She discusses how vaccines fit into today's immunotherapy landscape, the evolution of human epidermal growth factor receptor 2 (HER2)-targeted therapies, progress in breast cancer vaccines, the promise of cancer prevention, and the key priorities for survivorship and future oncology care.
Timestamps:
00:00 – Introduction
01:28 – Cancer Vaccines Explained
03:57 – Journey Into Cancer Immunology
06:38 – Cancer Vaccines in Immunotherapy
10:02 – Leading the Cancer Vaccine Institute
13:26 – Progress in Breast Cancer Vaccines
18:39 – HER2 Research and Treatment Evolution
21:30 – Future of Preventive Cancer Vaccines
26:39 – Priorities for Cancer Survivorship
30:30 – Three Wishes for Oncology's Future
How does scientific evidence become public policy? In the final episode, Christopher Cogle discusses the challenges of translating healthcare innovation into large-scale policy change. Topics include housing policy and mortality, youth tobacco use, vaping regulation, and how the COVID-19 pandemic reshaped public health decision-making.
Timestamps:
00:49 – Public Startup
07:08 - Challenges
15:01 – Housing policy
16:28 – Tobacco policy
19:05 – COVID-19
In Part 2, Christopher Cogle examines the long-term realities facing cancer survivors. From vaccine hesitancy and quality-of-life disparities to healthcare access and survivorship policy, this episode explores how systems can better support patients beyond active treatment.
Timestamps:
00:50 – Vaccine hesitancy
04:33 – QoL after cancer
07:30 – Policy support
11:10 – Survivorship care
In this episode of Hema Now, John Maher reflects on more than 2 decades at the forefront of CAR-T cell research. He discusses the major milestones that have transformed CAR-T therapy into a clinical reality, the biological barriers that continue to limit success in solid tumours, and the next-generation engineering approaches being developed to enhance efficacy and safety. Maher also shares insights into the origins of the CAR Mechanics Group, the challenge of overcoming the tumour microenvironment, and his vision for the future of cellular immunotherapy.
Timestamps:
00:00 – Introduction
01:07 – Career Journey into Immunotherapy
02:22 – Key CAR-T Therapy Milestones
05:50 – Overcoming Solid Tumour Barriers
09:14 – Origins of CAR Mechanics
12:35 – Most Exciting Current Innovations
16:08 – Improving CAR-T Safety Profiles
20:07 – Challenges of Tumour Microenvironments
23:04 – Future of Cellular Immunotherapy
27:15 – Three Magic Wishes
In this first deep dive, Christopher Cogle explores the evolving landscape of acute myeloid leukaemia (AML). He discusses the challenge of translating research into real-world outcomes, emerging immunotherapies, precision diagnostics, and how innovations such as the Acute Leukemia Methylome Atlas may reshape AML management in the future.
Timestamps:
00:55 – Research Gaps
03:50 – Biologics
05:46 – AML Atlas
09:15 – Immunotherapy
Christopher Cogle joins the EMJ Podcast for a quickfire discussion on oncology, innovation, and public health policy. From personalised cancer care and AI in medicine to AML challenges and healthcare reform, he shares concise insights from across clinical medicine and policy leadership.
In the final episode, Sharonne N. Hayes discusses how structural inequities and unconscious bias continue to affect cardiovascular outcomes for women and minority patients. From improving diversity in research to leveraging social media responsibly, this episode explores what the future of equitable cardiovascular care could look like.
Timestamps:
0:58 – Health equity
4:02 – Improving representation
7:10 – Role of social media
9:54 – 10-year prediction
11:08 – Sharonne's wish
In Part 2, Sharonne N. Hayes explores spontaneous coronary artery dissection (SCAD) and how it challenges traditional assumptions about heart attacks. Learn how SCAD differs from atherosclerotic disease, what recent research has uncovered, and how clinicians can navigate complex management decisions.
Timestamps:
1:06 – What is SCAD?
2:47 – Practice-changing insights
6:35 – Hormonal influences
8:20 – Therapeutic ambiguity
In this episode of Onc Now, Stephen Chan, Clinical Professor in the Department of Clinical Oncology at The Chinese University of Hong Kong, explores the evolving landscape of hepatobiliary and pancreatic cancers. From advances in translational science and precision therapies to the challenges of neuroendocrine tumour care, Chan reflects on the progress made in oncology and the breakthroughs still needed. He also discusses his work with the Hand-in-Hand Cancer Foundation, highlighting the importance of education, compassion, and holistic support for patients and their families.
Timestamps:
00:00 – Introduction
01:18 - Current Hepatobiliary and Pancreatic Landscape
03:23 - Translational Science and Patient Outcomes
05:06 - Founding the Hand-in-Hand Cancer Foundation
06:53 - Advances in Precision Cancer Therapies
08:54 – Rising Incidence of Pancreatic Cancer Post COVID-19
10:45 - President of the International Liver Cancer Association
12:46 - Challenges in Neuroendocrine Tumour Care
14:32 - Future Breakthroughs in Cancer Care
16:02 - Three Wishes for Oncology's Future
This podcast was developed by AMJ in collaboration with GSK and is sponsored by GSK. This information is scientific and non-promotional in nature, and intended for US audiences.
Less than 20% of biologic-eligible patients with GINA Step 5 asthma receive biologic therapy.1,2 In this AMJ podcast, experts discuss how real-world gaps in initiation, access, and adherence can affect whether patients start, stay on, and sustain benefit from biologic therapy over time.
Listen to the full episode to explore:
- Key real-world data on biologic initiation and adherence in severe asthma
- Patient cases showing common barriers across the care pathway
- Practical ways to uncover the burden of severe asthma
- The Start, Stay, Sustain framework for patient-centered care
Speakers:
- Justin Kwiatek, US Medical Affairs Lead, Respiratory Biologics, GSK
- Tom Corbridge, US Senior Medical Director, Respiratory Biologics, GSK
References
- Park J et al. Biologic underutilization and healthcare burden in US patients with Type 2 severe asthma. J Asthma Allergy. 2026;19:580937.
- Maselli DJ et al. Patient characteristics and social determinants of health influence adherence to biologic therapy for asthma. SEAAIS 80th Annual Meeting, October 23-26, 2025.
Sharonne N. Hayes joins host Saranya Ravindran to discuss how cardiovascular disease presents differently in women. From pregnancy-related complications and menopause to microvascular disease and gaps in clinician education, this episode explores the importance of sex-specific cardiovascular care.
Timestamps:
1:04 – Sex-specific differences
2:43 – Pregnancy and preeclampsia
4:38 – Historic underdiagnosis
7:00 – Menopause and hormones
10:04 – Education and training
In this rapid-fire episode, Sharonne N. Hayes answers key questions on women's cardiovascular health, SCAD, unconscious bias, prevention, and the future of equitable heart care. A concise, expert-led overview of the field.
In the final episode, Bryan Tucker explores the future of kidney stone prevention and treatment. From genetics and microbiome research to wearable hydration technology and AI-driven risk prediction, this episode examines how personalised medicine could transform nephrolithiasis care over the next decade.
Timestamps:
01:01 – Future changes in kidney stone care
04:21 – Microbiome and stone risk
05:34 – AI-driven risk prediction
07:02 – Ideal future of care
In Part 2, Bryan Tucker discusses the balance between acute intervention and long-term prevention in kidney stone care. Learn why many patients never receive comprehensive metabolic evaluation, how healthcare systems prioritise procedures over prevention, and what changes are needed to improve recurrence prevention.
Timestamps:
01:05 – Intervention and long-term prevention
04:01 – Gaps in follow-up evaluations
06:57 – Care changes for better prevention
This podcast has been funded by an educational grant from Viatris.
Systemic lupus erythematosus (SLE) is a complex, heterogeneous disease shaped by dysregulated immune pathways, variable organ involvement, and substantial patient burden. In this educational podcast, Anca Askanase explores how a deeper understanding of SLE immunology can help rheumatologists contextualize disease activity, evolving research, and guideline-based care.
Topics covered:
- Key immune pathways involved in SLE pathophysiology, including innate and adaptive immune dysregulation
- How pathway biology may help explain clinical heterogeneity and differences in disease activity between patients
- What rheumatologists should consider when interpreting emerging pathway-based research and cross-disease immunology concepts
- How current guideline-based care frames treatment goals, patient burden, and the evolving focus on remission in SLE
Speakers
Anca D. Askanase, Chair, Department of Medicine, and Chief, Division of Rheumatology, Hospital for Special Surgery, New York, USA
In this episode of Hema Now, we speak with Cecilia Karlström about advances in rare and complex haematological disorders. She discusses the evolving understanding of platelet refractoriness and transfusion support, the challenges in diagnosing systemic mastocytosis, and how targeted therapies are reshaping outcomes in rare blood diseases. The conversation also explores the growing role of precision medicine, multidisciplinary care, and future priorities in haematology research.
Timestamps:
00:00 – Introduction
01:21 – Career inspiration in haematology origins
02:43 – Evolution of platelet refractoriness management
03:39 – Current state systemic mastocytosis care
05:03 – Diagnosing systemic mastocytosis challenges today
07;26 – Impact of targeted therapies mastocytosis
07:26 – Future precision medicine opportunities haematology
09:00 – Multidisciplinary care improving patient outcomes
10:25 – Improving equity rare disease access
11:43 – Exciting research areas haematological disorders
13:14 – Three wishes future haematology advances
Bryan Tucker joins host Catherine Glass to explore why kidney stone disease is becoming increasingly common worldwide. From dietary and metabolic drivers to male predominance and prevention strategies, this episode examines how nephrolithiasis reflects broader shifts in metabolic health and lifestyle.
Timestamps:
01:13 – Increased prevalence
03:19 – Metabolic issues
04:30 – Increased prevalence in men
06:50 – Population-level prevention strategies
08:24 – Cardiometabolic syndrome
In this rapid-fire episode, Bryan Tucker answers key questions about kidney stone disease, from common myths and overlooked risk factors to hydration, prevention, and emerging technologies. Perfect for listeners short on time but looking for expert insights into the future of nephrolithiasis care.
In the final episode, Naveed Sattar explores the future of cardiometabolic medicine, from novel therapies and AI-driven risk prediction to integrated care pathways and the next generation of preventative strategies for diabetes and cardiovascular disease.
Timestamps:
0:56 – Novel interventions
2:10 – Digital health and AI
4:17 – Integrated care
5:26 – Future directions
7:11 – Naveed's prediction
In Part 2, Naveed Sattar discusses obesity, ectopic fat, and cardiovascular risk. Learn how imaging and biomarkers are improving risk identification, why metabolic dysfunction matters beyond BMI, and how GLP-1 therapies are reshaping obesity and cardiovascular care.
Timestamps:
0:56 – Ectopic fat
11:44 – Metabolic dysfunction
13:42 – GLP-1 receptor agonists
19:05 – Mechanistic insights
21:31 – Societal issues
Naveed Sattar joins host Catherine Glass to explore the complex relationship between diabetes and cardiovascular disease. From hyperglycaemia and inflammation to diabetes onset age and risk prediction, this episode examines the mechanisms and evidence shaping cardiometabolic care today.
Timestamps:
0:55 – Diabetes to heart disease
4:35 – Age of onset
6:21 – Statins
09:01 – Epidemiological insights
12:29 – Improving risk prediction
In this rapid-fire episode, Naveed Sattar answers key questions on diabetes, cardiovascular disease, obesity, prevention, and emerging therapies. From precision medicine and GLP-1 receptor agonists to lifestyle interventions and research advice, this concise episode provides expert insight into the future of cardiometabolic medicine.
In the final episode, the focus turns to prevention. Rachel Buckley examines whether Alzheimer's strategies should be sex-specific, the timing of interventions, and how lifestyle factors like physical activity contribute to brain resilience. The discussion also highlights gaps in research and the need for better integration of women's health data.
Timestamps:
00:00:45:13 – Sex-disaggregated data for prevention
00:03:26:15 – Sex-specific timing for therapeutics
00:05:07:20 – Non-pharmacological interventions
00:07:58:02 – Gaps in reproductive data
This episode explores how reproductive ageing and biological sex influence Alzheimer's disease risk. Rachel Buckley discusses menopause, hormonal changes, genetic factors such as the X chromosome, and emerging evidence showing differences in tau accumulation between women and men.
Timestamps:
00:00:55:03 – Menopause and Alzheimer's disease
00:04:51:11 – X chromosome in Alzheimer's disease
00:08:29:01 – Tau accumulation in women
00:10:43:09 – Hormone replacement therapy
00:14:22:24 – The sweet spot with hormone therapy
In this episode of Onc Now, Paolo Bironzo joins us to discuss the evolving landscape of thoracic oncology and the innovations transforming lung cancer care. From targeted therapies and immunotherapy selection to advances in mesothelioma treatment and molecular profiling, Bironzo shares insights into the challenges clinicians face today and the future of precision medicine. He also reflects on the importance of treatment de-escalation, the complexities of clinical trials, and offers advice for the next generation of oncologists.
Timestamps:
00:00 – Introduction
00:51 – Inspiration Behind Thoracic Oncology
03:17 – Current Challenges in Lung Cancer
04:50 – Impact of Targeted Therapies
07:14 – Selecting Patients for Immunotherapy
08:04 – Advances in Mesothelioma Treatment
14:52 – Molecular Profiling in Thoracic Cancer
19:52 – Challenges in Lung Cancer Trials
22:05 – Predicting Immunotherapy Response Challenges
24:23 – Future of Precision Medicine
26:05 – Advice for Early-Career Oncologists
28:40 – Three Wishes for Cancer Therapy
In this first deep dive, Rachel Buckley joins host Catherine Glass to explore how Alzheimer's disease risk can be detected before symptoms appear. From blood-based biomarkers like p-tau217, to AI-driven models of cognitive resilience, the episode examines how risk, progression, and protection can be better understood and predicted over time.
Timestamps:
00:00:57:11 – Phosphorylated tau and amyloid-PET
00:08:15:05 – Biomarkers, risk, and progression
00:11:18:04 – Brain resistance and cognitive resilience
00:15:23:23 – AI biases
In this rapid-fire episode, Rachel Buckley answers key questions on Alzheimer's disease, covering sex differences in risk, early predictors of progression, brain resilience, and the most actionable prevention strategies. A concise overview of the evolving science behind personalised Alzheimer's care.
In the final episode, host Saranya and Helen Brough examine the key gaps in allergy care across prevention, diagnosis, and long-term management, and how these challenges impact families in practice. It explores barriers to early peanut introduction, highlights inequalities in allergy care and the populations most affected, and looks at how digital tools, education, and outreach could help improve access to evidence-based care.
Timestamps:
00:43 – Gaps in allergy care
04:07 – Early peanut introduction
06:39 - Disparities in diagnosis
08:12 – Improve access to care
In Part 2, we explore the role of the skin barrier in food allergy development, from how environmental allergen exposure can drive sensitisation to whether early skincare can help prevent disease. Drawing on studies such as SEAL and recent European eczema guidelines, it also tackles common misconceptions and parental concerns, including topical steroid withdrawal and how best to provide reassurance.
Timestamps:
00:54:02 – Skin allergen exposure
03:50 – Optimising the skin barrier
06:46 – Proactive treatment of atopic eczema
08:17 – Applying treatments
11:41 – Topical steroid withdrawal
Helen Brough joins the Saranya to reflect on her work in paediatric food allergy, from personal experiences that shaped her career to landmark studies like LEAP, EAT, and ProNuts that transformed prevention and management. This episode explores early allergen introduction, evolving approaches to treatment, and what's driving the rise in food allergies in children.
Timestamps:
00:53 – Raising children with atopy
02:18 – Antibiotic exposure at birth
03:08 – Prevention of peanut allergies
05:22 – Introducing other allergens
08:09 – Multi-nut/sesame allergy
10:41 – Immunotherapy for severe allergies
13:36 – Prevalence of food allergies
In this short rapid-fire episode, Helen Brough answers key questions on food allergy, covering common triggers, peanut allergy myths, early allergen introduction, and whether allergies can be outgrown. It also touches on immune development, common mistakes, biomarkers, and future breakthroughs.
Description: Meghan Azad discusses the challenges of translating microbiome science into public health strategies. From policy gaps to social inequalities, this episode explores how evidence can be turned into meaningful support for families.
Timestamps: 02:20 – Critical windows 04:50 – Health inequalities 07:30 – Policy interventions 10:10 – Future directions
This episode examines how infant nutrition influences microbiome development and links to asthma risk. Azad discusses key discoveries from cohort studies and the role of early-life exposures in shaping disease trajectories.
Timestamps: 02:40 – Microbiome development 05:10 – Asthma risk link 07:50 – Feeding transitions 10:20 – Clinical counselling
In this episode of Hema Now, Giancarlo Castaman explores the evolution of haemostasis and haemophilia care, reflecting on how advances in understanding coagulation biology have transformed treatment strategies for patients with bleeding disorders. From the challenges of managing rare disorders and balancing bleeding and thrombosis risks, to the promise and limitations of gene therapy, this discussion highlights the innovations shaping the future of the field.
Timestamps:
00:00 – Introduction
01:34 – Origins in haemostasis research
02:49 – Haemophilia care through decades
05:40 – Challenges managing rare disorders
07:19 – Priorities leading haemostasis advancement
10:18 – Gene therapy future challenges
14:35 – International networks improving outcomes
16:40 – Balancing bleeding thrombosis risks
18:30 – Emerging therapies transforming haemophilia
21:03 – Future haemostasis research priorities
Azad explores the biological complexity of human milk and its role in shaping infant immunity. From immune-active components to variation in milk composition, this episode examines how early nutrition programs long-term health outcomes.
Timestamps: 02:30 – Milk composition explained 05:20 – Immune components role 08:10 – Variation in milk 10:40 – Growth and outcomes
In this rapid-fire episode, Azad addresses common myths around breastfeeding, microbiome development, and infant feeding practices. A concise overview of the key factors shaping early immune health.
In the final episode, Pranav Garimella explores glomerular and cystic kidney diseases, including IgA nephropathy and autosomal dominant polycystic kidney disease. Discover how personalised medicine, biomarkers, and earlier diagnosis are shaping the future of care in these complex conditions.
Timestamps:
01:11 – Current treatment for IgA nephropathy
02:24 – SGLT2 inhibitors
03:38 – Cystic kidney disease diagnosis
In Part 2, Pranav Garimella discusses major advances in diabetic kidney disease management. Learn how sodium-glucose cotransporter 2 (SGLT2) inhibitors and novel therapies are reshaping disease progression, and why early intervention is critical to improving long-term outcomes.
Timestamps:
01:07 – Practice-changing developments
05:10 – GLP-1 agonists
07:00 – Early intervention
08:43 – Unmet needs
Pranav Garimella joins host Catherine Glass to explore why early detection of chronic kidney disease remains challenging. From high-risk populations to emerging plasma and urine biomarkers, this episode examines how earlier diagnosis and improved risk stratification can transform patient outcomes.
Timestamps:
00:59 – Challenges of early detection
05:12 – Populations for intensive screening
09:08 – Plasma and urine biomarkers
13:45 – Biomarker-driven risk stratification
In this rapid-fire episode, Pranav Garimella answers key questions on chronic kidney disease, from early detection and screening challenges to future innovations in nephrology. A concise overview for clinicians and curious listeners alike.
In the final episode, Nanette K. Wenger discusses the ongoing challenges in awareness and access to cardiovascular care for women. From public health campaigns to mentorship and community initiatives, discover what's needed to close the gap.
Timestamps:
1:02 – Barriers in care
2:54 – Future directions
6:11 – Atlanta Women's Network
In Part 2, Nanette K. Wenger examines how underrepresentation in research shaped cardiovascular epidemiology in women. Learn about the impact of key guideline developments, and where critical data gaps remain.
Timestamps:
1:09 – Historical underrepresentation
5:05 – Evidence gaps
In this episode of Hema Now, Cynthia Dunbar discusses her pioneering career in translational stem cell biology. From the evolution of haematopoietic stem cell research to the clinical milestones that have propelled gene therapy into mainstream haematology, Dunbar shares insights on innovation, collaboration, and the future of patient care.
Timestamps:
00:00 - Introduction
01:35 - Origins in haematology research path
02:52 - Evolution of haematopoietic stem cell biology
06:35 - Milestones enabling gene therapy adoption
10:37 - Advances in bone marrow failure treatment
19:24 - Promise of natural killer (NK) cell therapies
24:09 - COVID-19 collaboration and crisis lessons
29:27 - Challenges in translational research pipeline
33:23 - Future breakthroughs transforming patient care
38:39 - Three wishes for research future
Nanette K. Wenger joins host Saranya Ravindran to reflect on her pioneering work in women's cardiovascular health. From challenging early misconceptions to advocating for inclusion in research, this episode explores how the field began to shift.
Timestamps:
0:58 – Nanette's inspiration
5:21 – Dismantling misconceptions
8:12 – Research obstacles
14:20 – Risk factors
In this rapid-fire episode, Nanette K. Wenger answers key questions on women's heart health - from prevention and lifestyle to mentorship, research gaps, and the future of cardiology. A concise, expert-led overview of the field.
In this episode of Onc Now, Christopher Wolfgang shares insights into the evolving landscape of pancreatic cancer research and treatment. From his early inspiration in oncology to pioneering surgical approaches and tackling tumour recurrence, Wolfgang discusses the challenges that persist in this complex disease space and the innovations shaping its future.
Timestamps:
00:00 – Introduction
01:28 - Career inspiration
03:24 – Impact of early training
05:00 - Advances in treatment
09:20 - Tumour recurrence research
11:25 - Surgical innovation impact
17:00 - Barriers to progress
20:24 - Future priorities
26:40 - Three healthcare wishes
Gupta examines disparities in food allergy and asthma outcomes, highlighting barriers to care and the role of policy, research, and innovation in improving health equity.
Timestamps:
01:00 – Racial and socioeconomic barriers
03:37 – Collaborations to reduce disparities
05:05 – Emerging therapies
10:08 – Future care
From early allergen introduction to digital health tools, Gupta discusses modern prevention strategies and how clinicians balance prevention with long-term management in food allergy care.
Timestamps:
00:51 – Key messages for families and clinicians
02:56 – Allergies and breast milk
04:17 – Ongoing allergies
06:50 – Allergy education
10:34 – Telemedicine and digital tools
11:45 – Mentoring
In this rapid-fire episode, Ruchi S. Gupta answers key questions about food allergy misconceptions, prevention strategies, and asthma care. A concise overview for clinicians looking to stay updated in minutes.
Ruchi S. Gupta explores how food allergy and asthma care have evolved over the past 2 decades, from guideline development to school-based programmes and early prevention strategies shaping paediatric care.
Timestamps:
00: 55 – Recent care evolution
04:12 – Primary care management
06:00 – Schools and community programmes
09:13 – Prevention strategies
In the final episode, Majid Fotuhi explores how purpose, social connection, and brain networks influence longevity and dementia risk. Learn how cultivating meaning in life can support cognitive health and long-term brain resilience.
Timestamps:
01:03 – Brain regions
02:19 – Dementia risk
02:42 – Role of clinicians
04:42 – Social connection
07:00 – Dr Fotuhi's book
In Part 2, Majid Fotuhi explains how stress and inflammation accelerate brain ageing. Discover the role of sleep in clearing toxins, the benefits of neurofeedback, and which brain training strategies truly enhance cognition.
Timestamps:
01:14 – Stress and inflammation
04:40 – Importance of sleep
08:16 – Benefits of neurofeedback
10:19 – Brain training
12:20 – Concussion and ADHD
In this episode of Hema Now, Robert Negrin, President of the American Society of Hematology (ASH), reflects on his distinguished career in stem cell transplantation and cellular therapy, and shares his vision for the future of the field. From shaping global haematology priorities to advancing innovative treatments such as CAR-T cell therapy, he explores both the remarkable progress and the ongoing challenges facing clinicians and researchers today. The conversation also highlights the importance of translational research, mentorship, and collaboration in driving meaningful improvements in patient care, while looking ahead to the technologies and breakthroughs that could redefine haematology in the years to come.
Timestamps:
00:00 - Introduction
01:20 - Presidency priorities, mission advancement
05:45 - Evolving global haematology needs
08:17 - Career inspiration, key developments
16:13 - Cellular therapy opportunities, challenges
19:47 - Translational research importance
22:22 - Future of stem transplantation
26:08 - Mentorship principles, trainee guidance
29:45 - Emerging technologies impact
30:40 - Three wishes, haematology future
Majid Fotuhi joins host Saranya Ravindran to explore how nutrition influences brain ageing. From anti-inflammatory diets and omega-3s to insulin resistance and metabolic health, this episode unpacks how what we eat shapes cognition and long-term brain resilience.
Timestamps:
01:10 – Mediterranean Diet
02:58 – Reducing Alzheimer's risk
03:37 – Dietary changes
05:44 – Metabolic dysfunction
08:00 – Exercise and Sleep
In this rapid-fire episode, Majid Fotuhi answers key questions on brain ageing - from memory-boosting habits and diet to stress, neurogenesis, and Alzheimer's risk. Perfect for a quick, science-backed overview of how to protect your brain.
This content has been funded by AstraZeneca, and is intended for healthcare professionals.
The content in this podcast is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment, nor to promote any specific product or therapy.
The guests have been compensated by AstraZeneca for their participation. The views expressed are their own and do not necessarily reflect those of the AMJ or AstraZeneca. If you choose to act on information discussed here, you do so at your own discretion.
Description:
As homologous recombination deficiency (HRD) testing becomes increasingly embedded in ovarian cancer pathways, clinicians need clear, operational guidance. This episode brings together expert perspectives on selecting tests, understanding outputs, and integrating results into guideline-aligned care.
Learn:
· HRD basics in plain language: what you're measuring and why
· Test selection and reporting nuances that affect downstream decisions
· Workflow design across oncology, pathology, and genetics
· Applying results to maintenance strategies and patient conversations
Speakers:
-
Rebecca Arend, Associate Director for Clinical Research, UAB O'Neal Comprehensive Cancer Center; Endowed Professor of Gynecologic Oncology, University of Alabama, USA.
-
Thomas Krivak, Director, Division of Gynecologic Oncology; Chief Surgeon, West Penn Hospital, USA.
-
Bhavana Pothuri, Gynecologic Oncologist, NYU Langone Health; Associate Professor, Department of Obstetrics and Gynecology, NYU Grossman School of Medicine, USA.
Järvinen-Seppo discusses how translational research is advancing understanding of early allergic disease, from maternal antibodies to global collaborations shaping the future of prevention and care.
Timestamps:
00:57 – Research scope
03:49 – Maternal antibodies
07:34 – Integrating new evidence
09:17 – International coordination
10:37 – Emerging areas
This episode examines the spectrum of food allergy, from IgE-mediated disease to food protein induced enterocolitis syndrome and eosinophilic conditions, and explores how diet, skin barrier function, and the microbiome interact in early life.
Timestamps:
00:53 – Spectrum of allergic diseases
05:00 – Nutrition and immune activation
07:22 – Atopic dermatitis
08:55 – IgE-mediated food allergy
10:28 – Future management pathways
In this episode of Onc Now, Claire Snyder explores the growing importance of patient-reported outcomes and quality of life in modern oncology care. She discusses the challenges and opportunities of integrating patient perspectives into routine practice, as well as the global effort to standardise these measures through initiatives such as the PROTEUS Consortium. The conversation also highlights the evolving needs of survivors of cancer, key priorities in survivorship care, and what the future holds for patient-centred oncology.
Timestamps:
00:00 – Introduction
01:41 – Modern oncology care
03:56 – Patient-reported outcomes (PRO) interest origin
05:10 - PRO implementation challenges
06:36 - PROTEUS Consortium mission
08:33 - Survivorship care priorities
09:45 - Childhood survivor insights
12:35 - Advice for newcomers
13:37 - Future quality of life developments
14:41 - Three wishes
Kirsi Järvinen-Seppo explores how the infant immune system develops, highlighting the role of maternal environment, breast milk composition, and early-life exposures in shaping allergy risk.
Timestamps:
00:57 – Infant immune system
02:06 – Maternal lifestyle factors
06:10 – Breast milk composition
10:13 – ESCAPE study
13:25 – Early sensitisation pathways
16:58 – Early risk stratification
In this rapid-fire episode, Kirsi Järvinen-Seppo tackles key questions on infant immune development, common misconceptions around food allergy, and the early-life factors that shape allergic disease. She also highlights emerging research on maternal influences, breast milk immunology, and prevention strategies that could transform clinical practice.
In the final deep dive, Cherry Lim looks ahead to the future of AMR surveillance. She discusses the role of microbiology labs, the value of imperfect datasets, and how integrating genomics, modelling, and cost-effectiveness could transform global health systems over the next two decades.
Timestamps
00:00 – Introduction
01:03 – Investing in diagnostics 02:36 – Routine surveillance data 03:53 – Global versus local AMR data 05:08 – Future health systems
In this second deep dive episode, Cherry Lim discusses how complex modelling approaches can translate into practical clinical insights. From counterfactual frameworks to real-world prescribing decisions, she explores how data-driven tools can support clinicians in choosing more effective antibiotic treatments.
Timestamps
00:00 – Introduction
01:03 – Understanding counterfactual frameworks
02:56 – Antibiotic choice and survival
05:08 – Clinical decision dashboards
06:24 – Assumptions in AMR modelling
In this episode of Hema Now, Marilyn Manco-Johnson explores the evolution and future of paediatric haemophilia care. From the early adoption of prophylactic treatment to today's rapidly advancing therapeutic landscape, she reflects on the milestones that have transformed outcomes for children. The conversation also dives into ongoing challenges, including joint health, variability in treatment response, and access to care, while highlighting emerging innovations such as gene therapy and non-factor therapies that could redefine long-term management.
Timestamps:
00:00 – Introduction
00:49 - Career inspiration
04:40 - Prophylaxis turning points
09:41 - Key care advances
12:12 - Current research questions
15:00 - Joint risk factors
19:10 - Emerging therapies impact
24:24 – Recognising joint pain
26:08 - Gaps in care
29:11 - Future priorities
In this first deep dive, Lim explores how routine hospital data and bacterial genomics are transforming our understanding of AMR. She explains how combining datasets and transmission models can uncover hidden pathways of resistance and highlights the challenges of working across diverse healthcare settings.
Cherry Lim joins the EMJ Podcast for a rapid-fire discussion on data, modelling, and antimicrobial resistance. From surveillance gaps to the role of AI, she shares insights into how data is shaping the future of AMR research and policy.
Monga reflects on global urology practice, prevention challenges, and equity in care delivery. This episode explores how stone management adapts across healthcare systems and what needs to change to improve outcomes worldwide.
Timestamps: 00:00 – Global experience 02:20 – Resource adaptation 05:00 – Public health challenges 07:40 – Equity in urology 10:30 – Future advice
From device development to real-world surgical impact, Manoj Monga discusses how innovation is transforming stone management. This episode covers emerging technologies, procedural advances, and the future of minimally invasive care.
Timestamps: 00:00 – Innovation pipeline 02:40 – Device development 05:30 – Surgical advances 08:10 – Technology trends 10:50 – Improving outcomes
In this episode of Onc Now, Patricia Ganz sits down with EMJ to explore the evolving field of cancer survivorship. From managing long-term treatment effects to improving transitions into post-treatment care, she highlights key gaps in research, the growing role of patient-reported outcomes, and the importance of integrating policy, advocacy, and clinical practice to better support survivors.
Timestamps:
00:00 – Introduction
01:24 - Career survivorship inspiration
03:10 - Survivorship field evolution
04:10 - Late effects challenges
06:40 - Post-treatment care transition
07:58 - Patient-reported outcomes impact
10:14 - Advocacy policy research intersection
13:29 - Advice for new researchers
15:07 – Bench to beside challenges
17:40 – Equipping younger clinicians
19:16 - Future survivorship innovations
20:14 - Three survivorship wishes
The following podcasts were funded by Edgewise Therapeutics.
Disclaimers: The views and opinions expressed in these podcasts are those of the individual speakers and do not necessarily reflect those of Edgewise Therapeutics or EMJ.
The speakers received honoraria for participating in this recording.
Becker muscular dystrophy (Becker) affects more than just motor function. This episode features Elias Bracamonte, an individual living with Becker, and Gloria Bracamonte, his wife and a Becker patient advocate. Through sharing their story, they dive into the quality of life impacts of Becker on patients and their loved ones.
Manoj Monga explores the evolving understanding of kidney stone pathophysiology, from metabolic drivers to recurrence risk. This episode unpacks how clinicians balance acute intervention with long-term prevention strategies.
Timestamps:
00:00 – Monga's background 02:30 – Pathophysiology explained 05:10 – Recurrence risk factors 08:20 – Dietary management 11:00 – Prevention versus surgery
In this rapid-fire episode, Manoj Monga tackles common myths about kidney stones, shares clinical preferences, and highlights key innovations shaping modern endourology. A concise, high-yield overview of the field.
What is the science behind early allergen introduction? In Part 2, Debbie Palmer explains the immunological basis of oral tolerance, addresses persistent myths, and outlines best practices for introducing allergens, especially in high-risk infants.
Timestamps:
00:56 – Allergen introduction
02:03 – Non-breastfeeding approaches
02:54 – Biggest myth
03:49 – Tolerance versus sensitisation
04:48 – High-risk patients
05:25 – Weaning diet
06:49 – Prohibited foods
In this episode of Hema Now, Karina Yazdanbakhsh speaks about her journey into immunology, the challenges of alloimmunisation, and the evolving landscape of transfusion medicine. She also reflects on receiving the prestigious Henry M. Stratton Medal for Basic Research at ASH 2025 and what this recognition means for her work. The conversation explores key insights from ASH 2025, highlights pressing immunological issues in sickle cell disease, and looks ahead to emerging technologies shaping personalised transfusion strategies.
Timestamps:
00:00 – Introduction
00:59 - Stratton Medal meaning
02:19 - ASH 2025 highlights
13:11 - Sickle cell challenges
17:00 - Immune tolerance evolution
18:55 - Institute research priorities
27:20 - Novel therapeutics role
29:04 - Early career advice
29:43 - Emerging technologies impact
32:30 – Three magic wishes for healthcare
In this episode, Aaron Phillips discusses haemodynamic instability following spinal cord injury, with particular focus on autonomic dysreflexia. The conversation reviews the neuronal mechanisms underpinning autonomic dysfunction, the clinical burden of hypertensive and hypotensive complications, and current management strategies. The episode also explores emerging therapeutic approaches, including the development and evaluation of implantable systems designed to restore haemodynamic stability.
Key Discussion Themes
-
Definition and clinical features of haemodynamic instability
-
Autonomic dysreflexia: mechanisms and patient impact
-
Chronic hypertensive and hypotensive complications
Debbie Palmer joins host Catherine Glass to explore how maternal diet shapes fetal immune development and influences allergy risk. This episode unpacks key nutrients, timing of dietary exposures, and findings from randomised trials that challenge conventional pregnancy nutrition advice.
Timestamps:
01:22 – Maternal diet
02:59 – Mid-pregnancy versus preconception
03:53 – Food groups
04:28 – Prebiotic supplements
05:30 – Pregnancy cravings
In the final episode of the series, David Goldstein examines orthostatic hypotension as a manifestation of autonomic failure in Parkinson's disease. The discussion explores the pathophysiology of cardiac noradrenergic deficiency, its identification and clinical implications, and current management approaches. The episode also considers the prognostic significance of orthostatic hypotension in Parkinson's disease and potential future directions in research and patient care.
Key Discussion Themes
-
Autonomic failure in Parkinson's disease
-
Cardiac noradrenergic deficiency: definition and identification
-
Clinical consequences, including falls and cognitive impairment
-
Mechanistic insights into sympathetic denervation
-
Current treatment approaches and guideline considerations
-
Future research priorities
In this episode, Satish Raj and Gert van Dijk explore the diagnosis, clinical burden, and management of orthostatic hypotension. The discussion examines how low blood pressure affects daily functioning, the importance of accurate diagnosis, and current treatment approaches.
Key Discussion Themes
- Definitions and subtypes of orthostatic hypotension
-
Differential diagnosis and the role of tilt-table testing
-
Impact on quality of life and daily functioning
-
Current treatment landscape and clinical guidelines
-
Unmet needs and future research priorities
In this rapid-fire episode, Debbie Palmer answers key questions on allergy prevention, from pregnancy nutrition myths and early allergen introduction to common misconceptions among clinicians and parents. A concise overview of cutting-edge thinking in just a few minutes.
In the final episode of this series, Leslie Cho focuses on prevention. From lifestyle interventions and pregnancy-related risk to menopause, brain health, and cholesterol management, she shares practical strategies clinicians can use today to improve long-term cardiovascular outcomes for women.
Timestamps:
01:02 – Lifestyle interventions
02:30 – Gestational hypertension
07:06 – Menopause
08:35 – Brain health
12:00 – Cholesterol levels
13:59 – Key message
This episode has been funded by Sun Pharmaceutical Industries, Inc. Please see full Prescribing Information and the Patient Information for clascoterone cream 1%.
Sebum plays a central role in acne pathogenesis. In this AMJ Rapid Review, Zoe Diana Draelos, MD, breaks down what new 52-week findings with clascoterone cream 1% may mean for everyday dermatology practice.
In under 15 minutes, learn:
- How did the study objectively measure sebum, and what makes that approach clinically useful?
- What did the 52-week results reveal about changes over time, beyond what you see in the first few visits?
- How might sebum trends relate to standard acne assessments in longer-term follow-up?
- What practical expectations and counseling tips can help patients stay on track with treatment?
Speaker:
Zoe Diana Draelos, MD
Dermatology Consulting Services, PLLC, North Carolina, USA
IMPORTANT SAFETY INFORMATION
Indication
What is WINLEVI cream?
WINLEVI (clascoterone) cream 1% is a prescription medicine used on the skin (topical) to treat acne vulgaris in people 12 years of age and older.
It is not known if WINLEVI cream is safe and effective in children under 12 years of age.
Important Patient Information
Before using WINLEVI cream, tell your healthcare provider about all of your medical conditions, particularly if you:
- have skin problems, including eczema, cuts or sunburn
- are pregnant or plan to become pregnant. It is not known if WINLEVI cream will harm your unborn baby
- are breastfeeding or plan to breastfeed. It is not known if WINLEVI cream passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with WINLEVI cream
WINLEVI cream is for use on the skin only (topical). Do not use WINLEVI cream in or on your eyes, mouth, or vagina. Do not use WINLEVI cream for a condition for which it was not prescribed. Do not give WINLEVI cream to other people, even if they have the same symptoms you have. It may harm them.
What are the possible side effects of WINLEVI cream?
WINLEVI cream can cause serious side effects, including:
- local skin reactions. WINLEVI cream may cause local skin irritation including itching, burning, skin redness or peeling.
- symptoms of a disorder where the adrenal gland does not make enough of certain hormones (adrenal insufficiency) during treatment with WINLEVI. Your healthcare provider may stop your treatment with WINLEVI if you develop any adrenal problems.
The most common side effects of WINLEVI cream include reddening, scaling or dryness, and itching of the skin being treated.
These are not all of the possible side effects of WINLEVI cream.
Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or to Sun Pharmaceutical Industries, Inc. by calling 1-800-818-4555.
Please see full Prescribing Information and the Patient Information.
Why does cardiovascular data so often fail women? In Part 2, Leslie Cho unpacks how trial design, symptom bias, and underdiagnosis of microvascular disease distort care for women, and what the evidence actually tells us about diagnosis, imaging, and treatment.
Timestamps:
00:50 – Misinterpretations
02:22 – Younger women
03:10 – Symptoms bias
05:05 – Microvascular dysfunction
07:17 – Cardiac PET
In this first deep dive, Leslie Cho explores how lipidology and hormone therapy intersect in women's cardiovascular care. Drawing on major guideline work and trial data, she explains how clinicians should approach menopausal hormone therapy, complex lipid disorders, microvascular disease, and emerging therapies through a precision lens.
Timestamps:
01:10 – Menopausal hormone therapy
03:45 – Lipid-lowering therapy
05:55 – Microvascular disease
07:55 – Testosterone therapy
In this rapid-fire episode, Leslie Cho answers essential questions on women's cardiovascular health, from overlooked risk factors and lipid values to myths about chest pain, microvascular disease, menopause, and the future of precision cardiology.
In the final deep dive, Matteo Bassetti discusses antimicrobial resistance beyond the bedside: translating evidence into policy, the importance of national surveillance, lessons from sepsis and COVID-19, and the future of antibiotic innovation and hospital preparedness.
Timestamps:
01:24 – Translating evidence into policy
02:54 – National surveillance
04:15 – Sepsis and COVID-19
06:18 – Investment shortfalls
08:41 – Antibiotic crisis
10:19 – Looking ahead
In the second deep dive, Matteo Bassetti examines antibiotic stewardship where policy meets practice. He highlights gaps between guidelines and bedside realities, practical interventions for limited-resource settings, and balancing preservation of new antibiotics with effective treatment today.
Timestamps:
01:27 – Guideline gaps
04:40 – Encouraging stewardship
06:23 – Realistic interventions
09:59 – Antibiotic shortages
11:16 – Preserving new drugs
In this episode of Hema Now, Ana Boban discusses her vision as the incoming EAHAD President for 2026–2028. From her early experiences in haemophilia care to her leadership in European clinical trials and guideline development, she reflects on the future of bleeding disorders in Europe, highlighting the importance of supporting young clinicians and researchers, advancing clinical practice, and driving innovation in haemophilia care and research.
Timestamps:
00:00 – Introduction
01:38 - Vision for EAHAD Presidency
03:50 - Building on Past Leadership
06:45 - Key Priorities: Practice, Research, Education
09:05 - EAHAD Congress Highlights
11:20 - European Haemophilia Landscape Today
14:17 - Advances Influencing Clinical Care
16:14 - Unmet Needs in Europe
17:45 - Supporting Young Clinicians, Researchers
20:00 - Long-Term Goals Beyond 2028
TBC- Three Wishes for Haemophilia
- In this first deep dive, Bassetti discusses the changing landscape of antimicrobial resistance in hospitals and ICUs, the challenges of multidrug-resistant Gram-negative bacteria, and the vulnerability of patients who are critically ill and immunocompromised. He explores how diagnosis, empiric therapy, and therapeutic monitoring influence outcomes and resistance.
Timestamps:
01:09 – Antimicrobial resistance trends
04:06 – Tackling sepsis
06:39 – Gram-negative threat
08:15 – Vulnerable populations
10:00 – Diagnosis and empiric therapy
12:14 – Dosing and pharmacokinetics
14:32 – Antibiotic allergies
Matteo Bassetti joins the EMJ Podcast for a rapid-fire discussion on antimicrobial resistance in hospitals. From prescribing pitfalls to early versus precise antibiotic use, he shares insights on howantimicrobial resistance is impacting real-world clinical care.
Drawing on her landmark work in HIV and vaccine research, Glenda Gray shares powerful lessons for tackling AMR in this last deep dive episode. From prevention and behavioural science to protecting high-risk populations, she explains how strategies that transformed HIV outcomes can inform a more effective and equitable AMR response.
Timestamps: 00:00 – Introduction
01:02 – Lessons from HIV
02:47 – Vaccine trials
03:50 – AMR interventions
05:17 – Behavioural science
06:31 – Key takeaways
In this second deep dive, Glenda Gray examines why the global antibiotic pipeline is failing and how access gaps are fuelling resistance. She discusses GARDP's mission-driven research and development model, the neglect of paediatric antibiotics, and how shortages of first-line treatments drive reliance on last-resort drugs, worsening the antimicrobial resistance crisis.
Timestamps: 00:00 – Introduction
00:58 – Antibiotic development
03:05 – GARDP's model
04:15 – Paediatric antibiotics
04:58 – Antibiotic shortages
05:50 – Access gaps
In this episode of Onc Now, Michael Cecchini, Associate Professor of Medicine at Yale School of Medicine, New Haven, Connecticut, USA, discusses his journey into gastrointestinal oncology and the evolution of care for patients with colorectal and rectal cancers. From the complexities of multidisciplinary coordination to the promise of early-phase clinical trials, Cecchini reflects on how molecular profiling and next-generation systemic therapies are reshaping treatment paradigms.
Timestamps:
00:00 – Introduction
01:13 – Path to gastrointestinal oncology
03:00 – Multidisciplinary care challenges
07:20 – Early phase trial advances
11:26 – Evolving systemic therapies
14:58 – Impact of molecular profiling
20:20 – Translating trials to practice
23:38 – Advice for clinician investigators
28:21 – Future therapeutic advances
31:50 – Three wishes for gastrointestinal care
In this first deep dive, Glenda Gray unpacks what antimicrobial resistance means for clinicians beyond infectious diseases, and why it is already a leading cause of death globally. She explores the disproportionate burden in low- and middle-income countries, the devastating impact on neonates and infants, and the critical role of diagnostics, vaccines, and infection prevention.
Timestamps: 00:00 – Introduction
00:45 – What is AMR?
01:32 – Burden on LMICs
02:57 – Impact on infants
04:05 – Diagnostic gaps
05:10 – Comprehensive strategies
Glenda Gray joins the EMJ Podcast for a quickfire discussion on antimicrobial resistance and child health. From antibiotic misconceptions to equitable access and stewardship, she shares sharp insights into why AMR is a defining global health challenge for children today.
Description: The final deep dive episode looks ahead: stem cells, tissue transplantation, fertility preservation in cancer care, and the policy challenges limiting access to advanced male infertility treatment. A future-facing discussion on cures and equity.
Timestamps: 00:00 – Introduction
01:02 – Stem cells
04:08 – Fertility preservation
05:04 – Access and cost
07:04 – Pricing variability
08:20 – What's next?
Description: In this second deep dive, Schlegel explains how microTESE transformed sperm retrieval. Learn how microsurgical precision improves outcomes, preserves testicular tissue, reduces pain, and why multidisciplinary collaboration drives high pregnancy rates.
Timestamps:00:00 – Introduction
01:06 – Why the microscope?
03:09 – MicroTESE advantages
04:11 – Success rates
06:29 – Postoperative care
08:04 – Multidisciplinary approaches
In this episode of Hema Now, Anna Schuh discusses the evolution of precision medicine in haematology. From her early inspiration to pursue haematology to her pioneering work in chronic lymphocytic leukaemia, she reflects on how whole genome sequencing, single-cell technologies, and circulating tumour DNA are transforming risk prediction and treatment strategies.
Timestamps:
00:00 – Introduction
02:20 – What drew Anna to haematology
03:57 – Chronic lymphocytic leukaemia
08:55 – Genomics reshaping high risk chronic lymphocytic leukaemia
12:19 – OxPLoreD and STELLAR aims
15:52 – Liquid biopsies
19:56 – Global diagnostics implementation challenges
25:57 – Integrating molecular testing clinically
29:20 – Training future precision leaders
33:51 – Next breakthroughs in precision haematology
35:35 – Three magic wishes
In this episode of Hema Now, Anna Schuh discusses the evolution of precision medicine in haematology. From her early inspiration to pursue haematology to her pioneering work in chronic lymphocytic leukaemia, she reflects on how whole genome sequencing, single-cell technologies, and circulating tumour DNA are transforming risk prediction and treatment strategies.
Timestamps:
00:00 – Introduction
02:20 – What drew Anna to haematology
03:57 – Chronic lymphocytic leukaemia
08:55 – Genomics reshaping high risk chronic lymphocytic leukaemia
12:19 – OxPLoreD and STELLAR aims
15:52 – Liquid biopsies
19:56 – Global diagnostics implementation challenges
25:57 – Integrating molecular testing clinically
29:20 – Training future precision leaders
33:51 – Next breakthroughs in precision haematology
35:35 – Three magic wishes
Description: In this first deep dive, Peter N. Schlegel joins host Catherine Glass to unpack non-obstructive azoospermia. Explore genetic discoveries, hormonal optimisation, age-related factors, and practical strategies that maximise sperm retrieval and conception potential.
Timestamps: 00:00 – Introduction
01:13 – Non-obstructive azoospermia
02:01 – Genetics of infertility
04:01 – Aromatase inhibitors
06:05 – Sperm quality
07:27 – Multiple semen samples
10:27 – Infertility globally
In this rapid-fire episode, Peter N. Schlegel answers key questions about male infertility, from what drives success in microTESE to the role of genetics, hormones, and surgical skill. A concise introduction to the science shaping modern men's reproductive care.
Bairey Merz discusses the latest directions in microvascular and endothelial research, including links to heart failure with preserved ejection fraction, integration of adverse pregnancy outcomes and autoimmune disease into models, and promising technological advances.
Timestamps:
00:53 – Directions of the WISE programme
01:47 – Preserved ejection fraction
04:51 – Adverse outcomes of microvascular disease
08:42 – Technology improving outcomes
This episode examines how diagnostic tools and imaging for microvascular dysfunction are evolving, the paradox of 'clear' arteries in symptomatic women, and barriers to broader implementation in clinical practice.
Timestamps:
00:45 – Angina in women
03:43 – Defining ischaemia
05:35 – Barriers to microvascular testing
In this episode of Onc Now, Kevin Harrington discusses the evolving landscape of head and neck cancer treatment, from the transformative impact of immunotherapy to the promise of oncolytic viruses. He reflects on the challenges that defined a decade of limited progress, the integration of radiotherapy and systemic therapies, and the importance of translating innovative science into clinical benefit. With insights into salivary gland cancers, combination strategies, and advice for the next generation of oncologists, this episode offers a comprehensive look at one of oncology's most rapidly advancing fields.
Timestamps:
00:00 – Introduction
01:10 – Specialisation in head and neck cancers
03:39 – Biggest challenges
06:30 – Impact of radiotherapy
11:19 – Role of systemic therapy
16:13 – Immunotherapy
21:10 – Salivary gland cancers
28:34 – Viruses as anti-cancer agents
33:22 – Translating innovative science
38:00 – Pairing viruses for certain cancers
41:47 – Advice to young oncologists
44:29 – Important breakthroughs
47:21 – Three magic wishes
Bairey Merz explores the science of microvascular dysfunction in women, the role of the WISE initiative, and how these findings have redefined diagnosis, preventive cardiology, and symptom assessment.
Timestamps:
01:04 – Barbra Streisand Women's Heart Center
03:35 – WISE initiative
06:36 – Microvascular angina
11:11 – Preventative cardiology
Noel Bairey Merz answers rapid-fire questions on women's heart health, including misconceptions about angina, key insights from the WISE study, and emerging imaging technologies.
In the final episode, Vidur Mahajan looks ahead to the future of radiology. From AI-enabled education to convergence with genomics and pathology, this discussion explores how imaging and AI will reshape diagnostics over the next decade.
Timestamps: 00:00 – Introduction
00:51 – Exciting innovations
03:47 – Role of radiologists
05:59 – AI and education
08:40 – AI and genomics
10:55 – What's next?
What does it take to deploy AI across national health systems? In Part 2, Vidur Mahajan shares lessons from large-scale rollouts at RadNet and Singapore's health network, covering interoperability, regulation, and success metrics.
Timestamps: 00:00 – Introduction
00:55 – Deploying CARPL
05:50 – Real-world stories
10:52 – Regulatory challenges
13:30 – Interoperability
16:17 – Success metrics
In this episode of Hema Now, we take a deep dive into myeloproliferative neoplasms (MPN), with a particular focus on myelofibrosis, one of the most complex and challenging MPNs to manage. Ciro Rinaldi discusses what distinguishes myelofibrosis from other chronic MPNs, the biological drivers of disease progression, and the critical role of inflammation and the bone marrow microenvironment. The conversation also explores emerging combination therapies, translational research hurdles, and how the management of myelofibrosis may evolve over the next decade.
Timestamps:
00:00 – Introduction
00:59 – Myeloproliferative neoplasms
04:00 – Myelofibrosis
09:58 – Ciro's interest in the field
13:39 – Disease drivers & progression to aggressive states
17:40 – Inflammation and the bone marrow environment
22:19 – Novel targets
27:45 – Splenomegaly and MPNs
32:19 – Translational research
36:25 – Future of myelofibrosis management
38:51 – Ciro's three magic wishes
Vidur Mahajan joins host Catherine Glass to explore how imaging AI earns clinician trust. Learn how CARPL.ai bridges the gap between research and practice, ensures transparency, and empowers radiologists to evaluate and deploy AI safely.
Timestamps: 00:00 – Introduction
01:01 – Behind CARPL.ai
03:55 – Addressing scepticism
06:47 – Barriers in AI implementation
09:29 – Ensuring transparency
11:43 – Common challenges
In this rapid-fire episode, Vidur Mahajan answers key questions about AI in radiology, from common misconceptions and bias to real-world performance, productivity tools, and what clinicians should be asking as AI enters daily imaging workflows.
Turning ideas into action, this episode focuses on how social health can be measured, funded, and implemented. Wijedoru discusses social prescribing, training clinicians to recognise disconnection, and simple steps individuals and organisations can take to strengthen social bonds. Timestamps: 01:18 – Measuring social health 03:45 – Training and infrastructure 06:20 – Social prescribing 09:15 – Everyday actions for connection
How can stories heal? Wijedoru discusses how storytelling helps people feel seen and understood, why it belongs alongside data-driven medicine, and how initiatives like Behind Your Mask foster empathy and connection among healthcare professionals. Timestamps: 01:05 – Origins of Behind Your Mask 03:30 – Why storytelling works 06:10 – Storytelling in medical culture 08:00 – Tools beyond stories
Nuclear medicine has undergone extraordinary transformation over the past decades, and it continues to redefine how cancer is diagnosed and treated. In this episode, Ken Herrmann reflects on his journey into nuclear medicine, the rapid evolution from PET to PET-CT, and the rise of theranostics. He discusses the balance between innovation and evidence, the growing role of multidisciplinary cancer care, and what lies ahead for the field, including the potential impact of AI. This is a forward-looking conversation for clinicians and researchers at every stage of their career.
Timestamps:
00:00 – Introduction
01:07 – His journey into nuclear medicine
02:45 – Impact of nuclear medicine
03:49 – The evolution of his research
05:22 – Theranostics
06:35 – What is the next breakthrough?
08:20 – Balancing innovation with evidence-based practice
09:45 – Multidisciplinary cancer care
11:30 – Biggest challenges in nuclear medicine
13:42 – Future of nuclear medicine
14:58 – Advice to early-career clinicians
16:00 – The potential of AI
17:57 – Three magic wishes for healthcare
In this episode, Wijedoru explains what social health really means and why it has been neglected for so long. Drawing on WHO frameworks and global experience, he explores how poor social health affects patients, communities, and healthcare systems, and why prevention must start with connection.Timestamps:01:10 – Background03:27 – Storytelling05:25 – Social health10:04 – WHO commission
Lalith Wijedoru answers rapid-fire questions on healthcare culture, loneliness, and emotional wellbeing. From lessons learned in low-resource settings to bold ideas for improving connection in hospitals, this episode introduces social health as a vital but under-recognised pillar of health.
In this final episode, Vallier explores the next steps for liver regeneration research, including stimulating liver regeneration with small molecules and lifestyle factors. He describes AI as a tool that should not be used in the wrong way, before wrapping up the discussion with his predictions for the next 5 years and the introduction of induced pluripotent stem cell clinical trials.
Timestamps:00:55 – Research beyond organoids
02:01 – Lifestyle factors
03:47 – Research funding
04:13 – AI in biotechnology
05:13 – Future of regenerative medicine
07:04 – Vision for stem cell therapies
In the second episode of the series, Vallier dives into clinical translation of research to different forms of liver disease, exploring how organoids may serve as an alternative to liver transplantation, and how immune compatibility differs between the two.
Timestamps:00:59 – Organoids versus transplantation
02:52 – Organoid immune compatibility
04:58 – Chronic liver diseases
06:15 – Clinical application
In this episode of Hema Now, Catherine Glass sits down with senior leaders from the European Association for Haemophilia and Allied Disorders (EAHAD) to go behind the scenes of the EAHAD 2026 Congress. The discussion explores the vision shaping the meeting, how the scientific programme is developed, and the key advances and challenges influencing haemophilia care across Europe, offering valuable insight for clinicians and researchers alike.
Timestamps:
00:00 – Introduction
01:41 – Vision of the EAHAD 2026 Congress
03:09 – Overview of the programme
06:46 – Behind the scenes of planning a congress
09:38 – New sessions to look out for
11:03 – Their programme highlights
13:38 – How the programme is curated
15:21 – Current landscape of haemophilia care in Europe
18:09 – Major advances in the field
20:25 – Unmet needs for patients
23:31 – Real-world data and registries
25:58 – Advice to young clinicians
27:28 – Hopes for the future of haemophilia care
30:21 – Their wishes for healthcare
In the final podcast of this three-part series, we hear expert insights into evolving guidelines, practical tools, and multidisciplinary collaboration for the optimal diagnosis and management of RCC.
Explore how healthcare professionals navigate RCC in daily practice, including the latest guidelines to the streamlining of referral pathways and evaluating treatment response.
In this first deep dive, Vallier discusses the current state of liver regeneration research. He explores how pluripotent stem cells can generate hepatocytes and biliary cells, and describes how organoids integrate into tissues whilst providing new insights into liver disease.
Timestamps:
00:53 – Liver regeneration at present
03:37 – Pluripotent stem cells
05:18 – Scaling clinical use of organoids
06:42 – Application to non-alcoholic fatty liver disease
09:22 – Ethical considerations
Ludovic Vallier joins the EMJ Podcast to answer rapid-fire questions about how regenerative technologies can be harnessed to tackle metabolic liver disease. From the biggest breakthroughs in regenerative hepatology to clinical misconceptions about stem cells, explore how this field of research is changing the liver disease landscape.
In the final episode, Gerber discusses how discoveries move from laboratory research into real-world patient care. Drawing on his experience in clinical trials, entrepreneurship, and national transplant policy, he shares insights into the future of transplantation and regenerative surgery.
Timestamps:
Pullquote and timestamps:
00:56 – Clinical trials
02:42 – Entrepreneurship in life sciences
04:13 – Academic institution support
06:28 – Improving organ allocation
08:02 – Future of transplant surgery
In this second deep dive, Gerber discusses his appointment as Chair of Surgery at the University of Cincinnati, Ohio, USA, and his vision for advancing a century-long legacy of excellence. He reflects on how military and academic leadership shaped his approach to mentorship and accountability, explores the future of equity in surgical training, and offers advice to aspiring academic leaders.
Timestamps:
01:00 – Role as Chair of Surgery
02:55 – Building legacy
04:50 – Military experience
07:13 – Makeup of surgery trainees
09:09 – Early career advice
In this episode, Robin Jones explores the complexities of sarcoma care, reflecting on his career journey, the challenges of diagnosis, and the evolving treatment landscape. The discussion spans unmet needs, promising research, and what the next decade may hold for patients with both localised and metastatic sarcomas, drawing on experience from clinical practice and trials across the UK and USA.
Timestamps:
00:00 – Introduction
00:57 – Robin's career journey
01:43 – Why sarcoma?
03:05 – Different types of sarcomas
05:09 – Diagnosis and treatment decision-making
07:19 – Challenges in recognising sarcoma
10:34 – Evolution of care for patients
13:10 – Promising therapies and research
15:25 – Working across the UK and USA
16:32 – Current unmet needs for patients
18:42 – The future of sarcoma care
21:34 – Robin's magic wishes for healthcare
In this first deep dive, Gerber explores how regenerative medicine is reshaping transplant surgery. He discusses advances in stem cell biology, tissue engineering, and ex vivo organ preservation, and examines how these technologies may expand organ viability and redefine surgical repair.
Timestamps:
01:18 – Tissue regeneration
02:19 – Evolution beyond traditional transplantation
04:04 – Ex-vivo organ preservation
05:09 – Extending organ viability
06:34 – Promising frontiers
09:04 – Bench to bedside
David A. Gerber joins the EMJ Podcast for a rapid-fire discussion on what drives innovation in transplant surgery. From misconceptions about organ transplantation to the technologies shaping the future of regenerative medicine, this episode offers a concise overview of a rapidly evolving field.
In this final deep dive episode, Stuart Elborn turns to healthcare systems and policy. He discusses the importance of registries, data sharing, and service organisation, alongside social and funding factors that shape equitable cystic fibrosis care, ending with a global vision for cystic fibrosis management over the next decade.
Timestamps:
00:00 – Introduction
01:08 – Healthcare delivery
03:33 – National registries
05:04 – New challenges
06:35 – Equitable care
08:51 – Regional initiatives
10:40 – What's next?
In this second deep dive episode, Stuart Elborn explores the future landscape of cystic fibrosis treatment beyond modulators. From mRNA and gene editing to inhaled therapies and phenotype-driven care, this episode examines how close we are to truly personalised medicine in cystic fibrosis.
Timestamps:
00:00 – Introduction
01:22 – Treatment gaps
03:13 – Extrapulmonary complications
04:14 – Novel therapies
06:04 – Delivery routes
07:33 – Personalised medicine
In this episode of Hema Now, Kenneth Anderson from the Dana-Farber Cancer Institute, Boston, Massachusetts, USA, shares his expert insights in multiple myeloma research. From key takeaways from the recent American Society of Hematology (ASH) Congress to efforts tackling drug resistance, and the challenges in translating laboratory science into the clinic, this episode is a must-watch.
Timestamps:
00:00 – Introduction
01:10 – Overview of multiple myeloma
04:45 – Kenneth's journey into medicine
07:44 – Myeloma microenvironment
13:40 – Bringing laboratory science to the bedside
16:18 – Exciting myeloma breakthroughs
24:00 – Targeting drug resistance
29:50 – Personalised medicine
34:20 – Importance of early intervention
39:40 – A message to those facing multiple myeloma
42:40 – Three magic wishes for healthcare
The evolving understanding of OA is reshaping how we diagnose, manage, and support patients. As research advances, OA is increasingly recognised as a complex condition influenced by inflammation, biomechanics, genetics, and lifestyle. This shift in perspective is transforming how OA is identified, managed, and experienced across the care pathway. Early intervention remains essential, before irreversible joint damage occurs. With personalised care, interdisciplinary support, and empowering strategies such as education and lifestyle modification, patients can take a more active role in their OA journey. Emerging tools and a proactive clinical mindset are paving the way for improved outcomes and a more positive future.
Topics covered:
· Redefining osteoarthritis beyond the "wear and tear "concept · The window of opportunity in early OA · Empowering patients through education and interdisciplinary care
OA is no longer just a "wear and tear" condition. It's a complex, multifactorial disease shaped by inflammation, biomechanics, genetics, and lifestyle. Early diagnosis and timely intervention can shift the course, preventing progression and unlocking the body's potential for self-healing. Today's OA care is moving beyond symptom management. Personalised treatment, interdisciplinary support, and patient empowerment through education and lifestyle changes are redefining what's possible. With emerging tools and a fresh clinical mindset, the future of OA management is proactive, hopeful, and tailored to each individual.
Topics covered:
· The complexity of pain, beyond biology · The power of validation in patient care · Self-healing as a new paradigm for patient's empowerment
In this first deep dive, Stuart Elborn reflects on the major scientific breakthroughs of his career, and how laboratory discoveries have transformed cystic fibrosis care. He discusses lessons from pivotal CTFR modulator trials, the role of consensus guidelines, and the challenges of caring for an ageing cystic fibrosis population.
Stuart Elborn joins the EMJ Podcast for a quickfire discussion on modern cystic fibrosis care. From CFTR modulators to antimicrobial resistance and personalised medicine, he shares concise insights into the biggest shifts shaping cystic fibrosis outcomes today.
Byrne discusses Dova's recent Late Breaker at the United European Gastroenterology (UEG) Week 2025, where AI re-analysis uncovered treatment effects missed by human readers. He explains how AI may soon become integral to clinical trial design, regulatory review, and drug approval, while predicting how AI-human partnerships will define the future of gastroenterology.
Timestamps:01:05 – AI in the TITRATE trial03:18 – Validating clinical endpoints04:16 – AI and human readers16:53 – The next frontier in gastrointestinal AI
Bias, privacy, and ethics take centre stage as Byrne discusses how to build trustworthy AI systems. From data transparency to global access, he shares practical steps to ensure equitable innovation and reflects on the fears clinicians express about integrating AI in their daily workflow.
Timestamps: 01:09 – Addressing bias and inequity 03:10 – Data privacy and regulation 04:40 – Trust and clinical accountability 06:52 – Educating clinicians on AI use
In this episode, Rob Jones, Professor and Honorary Consultant in Medical Oncology at the University of Glasgow, UK, joins us to discuss his journey into oncology, the future of the specialty, and the evolving treatment landscape for genitourinary cancers. From clinical trial design and emerging therapies to European Society for Medical Oncology (ESMO) 2025 takeaways and thoughts on prostate cancer screening, Jones shares practical insights drawn from both research and frontline clinical practice.
Timestamps:
00:00 – Introduction
00:43 – Rob's journey into oncology
04:11 – The next generation of oncologists
08:16 – Clinical trial work
10:20 – Intersection of oncology and nephrology
14:05 – Cardiovascular toxicity
19:25 – European Society for Medical Oncology (ESMO) 2025 bladder cancer takeaways
23:53 – Challenges in designing trials
26:35 – Emerging treatment strategies
30:18 – Prostate cancer screening
34:00 – Magic wishes for healthcare
Disclosure: Jones has received research grants from Astellas, Clovis, Exelixis, Bayer, and Roche; advisory board fees from Janssen, Astellas, Bayer, Novartis, Pfizer, Merck Serono, MSD, Roche, Ipsen, and Bristol Myers Squibb; lecture honoraria from Astellas, Janssen, Bayer, Pfizer, Merck Serono, MSD, Roche, Ipsen, and Bristol Myers Squibb; support for conference attendance from Bayer and Janssen; and participated on a Data Safety Monitoring Board or Advisory Board for Roche.
In this first deep dive, Byrne explores how AI is revolutionising inflammatory bowel disease care. He discusses the DovaVision™ UC (Dova Health Intelligence, Vancouver, Canada) Mayo Endoscopic Score developed with the Mayo Clinic; the power of multimodal AI in combining colonoscopy, ultrasound, and lab data; and how AI reduces interobserver variability in disease scoring.
Timestamps:01:04 – The landscape of AI in inflammatory bowel disease02:54 – DovaVision™ UC (Dova Health Intelligence, Vancouver, Canada) Mayo collaboration04:26 – Colonoscopy and AI08:30 – The future of multimodal AI
Michael Byrne joins the EMJ Podcast to tackle rapid-fire questions on AI's role in gastroenterology. From clinical misconceptions to the biggest breakthroughs in endoscopy, discover how intelligent tools are redefining precision medicine in inflammatory bowel disease.
In this special countdown episode, the EMJ Podcast team looks back at the 10 highest-performing episodes of 2025. Spanning neurology, cardiology, gastroenterology, women's health, respiratory medicine, and digital innovation, these conversations captured the topics that mattered most to clinicians worldwide. From chronic pain and anxiety to glucagon-like peptide-1 therapies, antimicrobial stewardship, and extended reality in medicine, this episode revisits the expert insights, emerging ideas, and clinical debates that shaped healthcare discussions throughout the year.
Timestamps:
00:00 – Introduction: the year in review 01:52 – Gravity and human health 06:28 – Antimicrobial stewardship in children 10:15 – Healthcare communication and leadership 13:04 – Rare lung diseases and early diagnosis 16:56 – Colonoscopy and cancer prevention 21:17 – Extended reality in clinical care 25:25 – Advances in heart failure research 34:07 – Obesity management in the GLP-1 era 20:35 – Women's health across borders 39:40 – The pain–anxiety connection
In this special two-part episode of Onc Now, Catherine Glass returns to take you through the incredible lineup of guests from 2025. From award winners to pioneering clinicians and researchers, this podcast has spotlighted some of the leading voices in oncology. Explore their most impactful insights and hear how recent advances are shaping clinical practice and future research.
Timestamps:
00:00 – Introduction
01:15 – Landscape of HER2 breast cancer
06:03 – Evolution of lung cancer research
09:10 – Breakthroughs in kidney cancer care
11:45 – A new era in liver cancer treatment
]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]" dir="auto" tabindex="-1" data-turn-id= "request-WEB:999cd22f-377a-429b-92bd-84de1f700f39-1" data-testid= "conversation-turn-4" data-scroll-anchor="true" data-turn= "assistant"> ]:pointer-events-auto scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]" dir="auto" tabindex="-1" data-turn-id= "request-WEB:999cd22f-377a-429b-92bd-84de1f700f39-1" data-testid= "conversation-turn-4" data-scroll-anchor="true" data-turn= "assistant"> In this third and final deep-dive episode, Nicholas Simmonds highlights the importance of collaborative networks, such as the European Cystic Fibrosis Society (ECFS) Clinical Trials Network, in enabling global clinical trials. He also emphasises the central role of the patient voice in developing new therapies, using CFTR modulators as a key example.
Timestamps:
00:00 – Introduction
00:55 – ECFS Network
03:29 – Trial design
04:54 – Therapy frontiers
07:48 – Curative approaches
13:07 – Clinician message
How is cystic fibrosis diagnosis evolving? In this second deep dive, Nicholas Simmonds explores advances in diagnostic tools and shares his experience with the CF registry, highlighting its value as a powerful resource for tracking long-term treatment effectiveness. A must-listen for clinicians and anyone interested in how cystic fibrosis is diagnosed, and how progress is monitored over time.
Timestamps:
00:00 – Introduction
00:52 – Adulthood diagnosis
06:00 – Advanced diagnostics
10:37 – Survival variability
15:05 – CF Registry
Nicholas Simmonds joins host Saranya Ravindran for a deep dive into how adult cystic fibrosis (CF) care is evolving. Drawing on decades of experience, he discusses the major shifts in adult CF management, the vulnerable transition from paediatric to adult services, and strategies that ensure a smooth handover. Explore how longer survival brings new challenges, from fertility to mental health and emerging comorbidities, and why continuity of multidisciplinary care is more crucial than ever.
Timestamps:
00:00 – Introduction
01:15 – Adult care
04:12 – Smooth handover
10:10 – Evolving needs
In this rapid-fire episode, Nicholas Simmonds answers key questions about cystic fibrosis (CF), from common misconceptions and the value of registry data to CF testing, and the transition from paediatric to adult care. Perfect for listeners short on time.
In the final part of this deep dive series, David Heymann looks ahead to future threats, from antimicrobial resistance to zoonotic spillovers, and the innovations that offer hope. He discusses next-generation diagnostics and vaccines, the rise of the One Health approach, and the need for better global financing and communication strategies. The episode closes with guidance for future public health leaders.
Timestamps:
00:00 – Introduction
01:40 – Next pandemic
02:29 – Today's threats
04:27 – Diagnostic innovations
05:47 – Vaccine innovations
06:21 – One Health
08:20 – Funding
10:38 – Addressing misinformation
15:42 – Advice for the next generation
In Part 2 of this deep dive series, David Heymann examines how global surveillance systems operate, why international coordination remains difficult, and how eradication efforts, such as those for polio, continue to strengthen health infrastructures. He reflects on the realities of responding in low-resource settings and the tension between rapid emergency interventions and sustainable system-building.
Timestamps:
00:00 – Introduction
01:00 – Disease surveillance
02:44 – International coordination
04:39 – Polio eradication
06:20 – Low-resource settings
08:46 – Rapid response versus capacity building
10:04 – Lessons learnt
In this special two-part episode of Onc Now, Catherine Glass takes you through the incredible line-up of guests from 2025. From award winners to pioneering clinicians and researchers, this podcast has spotlighted some of the leading voices in the field of oncology. Explore their most impactful insights and hear how recent advances are shaping clinical practice and future research.
Timestamps:
00:00 – Introduction
1:17 – Importance of palliative care
5:55 – Obesity and carcinogenesis
9:28 – Colorectal cancer advances
12:06 – Navigating fertility preservation
15:06 – ESGO 2025 reflections
17:44 – The future of cancer vaccines
22:18 – Impact of diet on prostate cancer
David Heymann joins host Jonathan Sackier to reflect on the defining outbreaks that shaped modern epidemiology. He recounts early Ebola investigations, compares SARS-CoV-1 with SARS-CoV-2, and revisits the smallpox eradication campaign. This episode offers rare insights into the field experiences that transformed global preparedness.
Timestamps:
00:00 – Introduction
01:07 – Ebola
05:51 – SARS-CoV-1 versus SARS-CoV-2
08:11 – Smallpox
09:26 – Insights from the field
10:28 – Milestones
In this quickfire episode, David Heymann answers essential questions about outbreak response, pandemic preparedness, and the future of global health. From the biggest misconceptions about infectious diseases to the threats we're overlooking, this introduction sets the stage for the full series.
In the final instalment of this episode on paediatric cystic fibrosis, Lisa Saiman explores the global inequities that persist, noting how progress is hindered by limited access to advanced antimicrobial resistance prevention tools such as sequencing and pathogen identification. She emphasises the need for strengthened international collaboration to help bridge these gaps.
Timestamps:
00:00 – Introduction
00:56 – Care inequities
03:30 – Global lessons
07:08 – Global collaborations
08:56 – Future directions
How can the threat of antimicrobial resistance be mitigated? In this second deep-dive episode, Lisa Saiman shares insights into the value of antibiotic stewardship and the nuance of microbial susceptibility testing in patients with cystic fibrosis. A must-listen for anyone curious about the overlap between cystic fibrosis and pathogen resistance.
Timestamps:
00:00 – Introduction
03:30 – Antimicrobial resistance threat
04:20 – Antibiotic stewardship
07:00 – Hospital lessons
10:00 – New antimicrobials
Lisa Saiman joins host Saranya Ravindran to discuss infection prevention in children with cystic fibrosis, exploring evolving hospital and clinical practices, key respiratory pathogens, and practical strategies to reduce infection risk at home. Learn about how the risk of infection affects the day-to-day lives of patients with cystic fibrosis.
Timestamps:
00:00 – Introduction
01:05 – Prevention importance
04:34 – International management
05:58 – Cross-infection risk
06:55 – COVID-19 lessons
07:43 – Home risk
10:57 – Childhood pathogens
In this rapid-fire episode, Lisa Saiman answers key questions about infections in children with cystic fibrosis, from everyday prevention measures to the threat of antimicrobial resistance. Perfect for listeners short on time but eager to boost their paediatric cystic fibrosis knowledge in just a few short minutes.
In this episode, Catherine Glass is joined by Anna Minchom, Clinical Scientist at the Drug Development Unit at the Royal Marsden Hospital and the Institute of Cancer Research, London, UK. In a highly informative discussion, Minchom explains the drug development process, key considerations in designing and conducting a trial, and the challenges in drug resistance.
Timestamps:
00:00 – Introduction
00:51 – Her journey into oncology
4:04 – Drug development
07:20 – Patient recruitment
08:45 – Challenges of drug resistance
11:20 – Early-phase clinical trials
13:06 – Navigating clinical trial outcomes
15:38 – Emerging technologies and therapies
17:42 – Side effects
19:09 – Three magic wishes
What does body dysmorphic disorder (BDD) look like in young people? In Part 3, Katharine Phillips discusses developmental differences in symptoms across children, adolescents, and diverse cultural or gender groups. She outlines early warning signs, risk factors that shape long-term outcomes, and how clinicians can distinguish BDD from related disorders such as obsessive-compulsive disorder and social anxiety, a vital conversation for anyone involved in paediatric mental health.
Timestamps:
00:50 – Age differences
03:55 – Warning signs
07:15 – Social media
08:42 – Prognosis
10:17 – Obsessive-compulsive disorder
14:15 – Future of BDD
In Part 2, Katharine Phillips breaks down what current evidence reveals about cognitive behavioural therapy (CBT) and pharmacological treatments for BDD. She shares the challenges of developing specialised CBT protocols, the role of selective serotonin reuptake inhibitors and combined therapy, and practical tools like mirror retraining. The episode also looks toward the future, highlighting emerging biological and digital interventions, including the potential of virtual reality.
Timestamps:
01:05 – Aesthetic treatments
07:00 – Suicide risk
09:55 – Gender differences
11:59 – CBT
17:00 – Medications
19:47 – Combined therapy
21:38 – Mirror retraining
25:00 – Digital approaches
Katharine Phillips joins host Catherine Glass to explore how brain circuitry, heritability, and visual processing abnormalities contribute to body dysmorphic disorder. Drawing on decades of clinical research, she discusses chronicity, recovery patterns, and how surgeons can better identify patients seeking aesthetic procedures for BDD. This episode unpacks the neurobiological and behavioural roots behind the disorder.
Timestamps:
01:05 – Clinical features
02:25 – Neurobiology
05:10 - Interventions
08:50 – Longitudinal research
11:10 – Patient insight
In this rapid-fire episode, Katharine Phillips answers essential questions about body dysmorphic disorder (BDD), from early signs and common misdiagnoses to key medications, childhood prevalence, and what truly distinguishes BDD from everyday appearance concerns. A perfect 5-minute listen for clinicians and curious minds wanting a fast, high-impact overview of BDD.
Rockstroh examines emerging challenges in HIV care, including COVID-19 and mpox, novel therapies, and lessons from Europe's care model. Explore the possibilities of shifting from disease management towards long-term remission and functional cure.
Timestamps:
00:00 – Introduction
00:45 – COVID-19 lessons
05:02 – Mpox challenges
07:42 – Novel therapies
12:56 – Improving care
15:39 – Remission or cure?
From HIV/hepatitis co-infections to haemophiliac cohorts, Rockstroh shares strategies for managing complex patient populations. Discover how antiretroviral therapy, multidisciplinary care, and lifestyle interventions work together to optimise outcomes.
Timestamps:
00:00 – Introduction
01:17 – HIV/hepatitis co-infection
05:43 – Cardiovascular risk
08:06 – Haemophiliac cohorts
11:47 – Multidisciplinary care
In this special two-part episode of Hema Now, Catherine Glass takes you through the incredible line-up of guests from 2025. From congress presidents to pioneering clinicians and researchers, this podcast has spotlighted some of the leading voices in the field of Hematology. Explore their most impactful insights and hear how recent advances are shaping clinical practice and future research.
Timestamps:
00:00 – Introduction
01:04 – Advances in lymphoma and transplant
06:15 – Epigenetics in leukaemia
08:46 – Multiple myeloma care today
11:49 – Metabolism's role in leukaemia
14:51 – Myeloid malignancy biology and treatment
16:50 – New therapies for chronic lymphocytic leukaemia
21:44 – Outro
AMJ Podcast | Episode 4
Capivasertib in the Clinic: Strategies to Manage Adverse Events
This content was funded by AstraZeneca, and is intended for US Healthcare Professionals. Expert opinions are shared in this program and may differ from the approved capivasertib (TRUQAP®) labeling. Please see full Prescribing Information, including Patient Information when making treatment decisions.
Indication and Usage
Capivasertib (TRUQAP®) in combination with fulvestrant is indicated for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN alteration as detected by an FDA-approved test following progression on at least one endocrine-based regimen in the metastatic setting or recurrence on or within 12 months of completing adjuvant therapy.
Description
In this practical, case-based discussion, a breast oncology pharmacist and nurse practitioner walk through how they anticipate and manage the most common adverse events seen with capivasertib in HR-positive/HER2-negative advanced breast cancer.
Drawing on real-world clinic workflows, they share stepwise approaches to counseling, prophylaxis, and early intervention for diarrhea, rash, and hyperglycemia, including when to escalate monitoring or treatment and how to coordinate roles across the care team.
You'll hear communication scripts, tips for using tools such as stool diaries and home glucometers, and strategies to keep patients on therapy safely and confidently.
Chapters
- 00:00 – 03:24 | Introduction
- 03:24 – 05:18 | When to consider capivasertib
- 05:18 – 08:51 | Introducing adverse events
- 08:51 – 16:18 | Diarrhea management
- 16:18 – 20:35 | Rash management
- 20:35 – 25:07 | Hyperglycemia management
- 25:07 – 27:31 | Care team best practices
- 27:31 – 31:18 | Top Tips & Takeaways
Speakers:
Heather Moore – Breast Oncology Pharmacist, Duke University Medical Center
Sarah Donohue – Breast Oncology Nurse Practitioner, UCSF Health Breast Care Center
Select Safety Information About capivasertib (TRUQAP®) tablets
TRUQAP is contraindicated in patients with severe hypersensitivity to TRUQAP or any of its components.
Serious adverse reactions include hyperglycemia, including diabetic ketoacidosis and fatal outcomes; diarrhea; and cutaneous adverse reactions. Monitor fasting glucose and hemoglobin A1C levels regularly. May cause fetal harm when administered to a pregnant woman. Among the 355 patients who received TRUQAP in CAPItello-291, the most common (≥20%) adverse reactions, including laboratory abnormalities, were diarrhea (72%), cutaneous adverse reactions (58%), increased random glucose (57%), decreased lymphocytes (47%), decreased hemoglobin (45%), increased fasting glucose (37%), nausea and fatigue (35% each), decreased leukocytes (32%), increased triglycerides (27%), decreased neutrophils (23%), increased creatinine (22%), vomiting (21%), and stomatitis (20%).
Please see full Prescribing Information, including Patient Information for TRUQAP.
Jürgen Rockstroh discusses decades of progress in European HIV care, including treatment access, patient outcomes, early diagnosis, and the role of pre-exposure prophylaxis. Explore how European societies have standardised care to improve outcomes across diverse healthcare systems.
Timestamps:
00:00 – Introduction
00:57 – Key developments
03:18 – Earlier diagnosis
05:31 – Long-acting PrEP
07:58 – European societies
10:38 – Shifting clinical practice
In this rapid-fire episode, Jürgen Rockstroh answers key questions about HIV care, from common misconceptions and transformative developments to policy priorities and the European approach to treatment. A concise, high-value overview in just a few minutes.
From CFTR modulators to gene therapy, what's next in cystic fibrosis research? Peter Mogayzel examines future therapies, ongoing access challenges, and the crucial link between advocacy, innovation, and global health equity in cystic fibrosis care.
Timestamps:
00:00 – Introduction
01:05 - CFTR modulators
03:35 – Anti-inflammatory drugs
04:18 – mRNA therapy
04:53 – Side effects
07:13 – Access to care
08:37 – Exercise
10:00 – Final thoughts
What defines excellence in cystic fibrosis clinical care? Peter Mogayzel discusses the latest therapeutic guidelines, managing pulmonary exacerbations, the role of home monitoring, and how multidisciplinary teams work together to support patients in leading full, active lives.
Timestamps:
00:00 – Introduction
00:41 – Key guidelines
01:54 – Multisystem disease
02:32 – Pulmonary exacerbations
04:04 – Chronic medications
05:37 – Home monitoring
08:15 – Multidisciplinary care
In this episode of Onc Now, Catherine Glass speaks with thoracic oncology expert Nicolas Girard about the evolving landscape of lung cancer treatment. They discuss current standards of care, practice-changing research, and the impact of precision medicine and immunotherapy on patient outcomes. Girard also shares insights from ongoing studies at Institut Curie, Paris, France, and offers his vision for the future of thoracic oncology.
Timestamps:
00:00 – Introduction
00:54 – Origin of interest in thoracic oncology
02:30 – Current standard treatments for lung cancer
05:17 – Practice-changing studies in this space
06:28 – Current research initiatives at Institut Curie
08:00 – Genomics and biomarker-driven therapies
09:30 – Optimising immunotherapy for different patient populations
11:10 – Importance of lung cancer screening
13:28 – Three magic wishes for healthcare
How did the USA build one of the world's most comprehensive cystic fibrosis care systems? In Part 1 of our deep dive, Peter Mogayzel explores the development of national cystic fibrosis centres, the impact of newborn screening, and how a strong foundation in care standards transformed outcomes across generations.
Timestamps:
00:00 – Introduction
01:38 – Care models
02:40 – Early screening
04:20 – CF Foundation
05:33 – What's changed?
In this quickfire introduction, Peter J. Mogayzel answers fast questions about the evolution of cystic fibrosis care in the USA, from early screening and survival milestones to innovation, policy, and equitable access. A perfect primer on where cystic fibrosis care stands today.
In the second episode of this three-part series, we delve into the science behind Refractory Chronic Cough (RCC), focusing on the role of neuronal hypersensitivity and how the cough reflex becomes dysregulated.1 Join leading experts as they explain the neurobiology of RCC, discuss the latest research, and share practical insights for identifying RCC in clinical practice.
Could 'gravity prescriptions' become a new form of therapy? Spiegel explores the concept of bio-gravitational medicine, from flotation tanks to National Aeronautics and Space Administration (NASA)-developed rehabilitation technology, and how virtual reality may help patients simulate weightlessness. He also predicts what the next decade of gravity research will bring.Timestamps:01:20 – Bio-gravitational medicine explained04:15 – Gravi-type09:08 – Anti gravity devices11:09 – Virtual reality
How does gravity shape our internal ecosystems? Spiegel explains the emerging science linking the microbiome, serotonin, and balance. He discusses how microgravity alters gut health in astronauts and why posture could affect digestion and mood on Earth.Timestamps:00:59 – Microbiome and balance03:36 – Microgravity gut effects06:25 – Serotonin and gravity link09:10 – Tools for studying gut-gravity
In this first deep dive, Spiegel unpacks his bold hypothesis: that irritable bowel syndrome and similar disorders could stem from gravity intolerance. He discusses his self-experiment simulating stronger gravity, the role of core strength in symptom relief, and how altitude affects gastrointestinal conditions.
Timestamps:01:04 – What is gravity intolerance?
02:55 – Gravity and chronic conditions
06:18 – Gravity and irritable bowel syndrome
09:29 – Self experiment
12:37 – Gravity's effect on pregnancy
16:43 – How should patients and clinicians think about gravity?
Brennan Spiegel answers rapid-fire questions about the effects of gravity on the human body and mind. From fatigue to irritable bowel syndrome to mental health, learn why gravity might be one of medicine's most overlooked forces, and how virtual reality is helping researchers study its effects.
In this episode of Hema Now, Diana Passaro from the Institut Cochin in Paris, France, shares her insights into tumour dissemination and the infiltration of the central nervous system by leukaemic cells. She discusses the mechanisms that regulate cell‑cell interactions within the microenvironment and how emerging tools like spatial transcriptomics are shaping the next generation of leukaemia research.
Timestamps:
00:00 – Introduction 01:15 – Origin of interest 03:30 – Influences on research 05:30 – Work highlights 07:09 – Leukaemia challenges 08:50 – Cell–microenvironment interaction 11:55 – Science at the interfaces 15:20 – Cross-disciplinary work 16:50 – Tumour spread context 19:50 – Innovations and technology 21:01 – Future of research 23:31 – Final takeaways
In this final episode, Ghatak and Olivo reflect on leadership, mentorship, and the legacy of innovation in diagnostics. Discover what drives them to keep pushing the boundaries of healthcare technology.
Timestamps:
00:00 - Introduction
00:45 - Good leadership
05:04 - Advice for young professionals
07:34 - Diagnostic gaps
09:34 - Maintaining motivation
10:33 - ImmunoProfile legacy
In this special World Mental Health Day episode, Jonathan Sackier speaks with Debi Roberts about breaking down barriers to mental health conversations and creating practical pathways for suicide prevention. From developing the Safe Plan and Prescription Safe Plan, to applying the Theory of Constraints in mental health systems, Debi brings clarity and compassion to one of society’s most complex challenges. Together, they explore how education, storytelling, and community collaboration can empower individuals to act, connect, and care.
Timestamps
00:00 – Introduction
03:30 – Debi’s career path
05:52 – Emotional literacy
08:15 – OLLIE Foundation
11:00 – Debi’s current work
13:53 – Unpacking ‘safe plans’
16:55 – The Prescription Safe Plan
21:23 – Theory of Constraints in suicide prevention
26:57 – Theory of Constraints in healthcare
33:00 – Societal views on suicide
39:49 – Reaching younger audiences
42:13 – It takes a village
46:05 – A message on World Mental Health Day
Description: In the final episode, Sandy Phanor delves into how her background in law helps her to maintain her confidentiality and professionalism in the clinic. She also looks towards the future, discussing technological advancements and the future of holistic care.
Timestamps:
01:14 – Law influence
02:15 – Osteopathy evolution
03:26 – Personalised plans
05:19 – Future technologies
7:00 – Holistic future
Description: What role does osteopathy play in sports injury rehab? And how does it differ between an office worker and an athlete? Sandy Phanor answers these questions, as well as explaining the benefits of good patient education in preventing repeat injuries.
Timestamps:
01:19 – Sports people
03:18 – Balancing recovery
04:30 – Office versus athletics
05:29 – Interesting case
06:51 – Patient education
In this episode of Hema Now, the authors sit down with Sunil Gupta to explore how advances in haematology are transforming both research and patient care. From breaking down misconceptions about stem cell donation to discussing emerging technologies, such as machine learning, Gupta shares insights into the breakthroughs, challenges, and future directions in the field. The episode also highlights his latest research and key takeaways from EHA2025, offering listeners a unique perspective on where haematology is heading next.
Timestamps:
00:00 – Introduction
01:54 – Biggest breakthrough in haematology
02:59 – Biggest challenge persisting
03:50 – Misconceptions about stem cell donation
05:27 – Emerging technologies
05:55 – Overview of Sunil’s research
09:30 – AI in haematology
13:01 – Key takeaways from EHA2025
17:56 – Translating research into patient care
Sandy Phanor reflects on her experiences in the clinic and explains how she harnesses the power of emotional connection with her patients, who now actively seek osteopathic appointments. Additionally, she explains her internal flow chart to assess patients. and how she ensures she uses the right technique in each situation.
Timestamps:
01:16 – Emotional connection
03:18 – Emotional manifestations
05:59 – Which technique?
08:28 – Lifestyle effects
11:00 – Patient relationships
In this rapid-fire episode, Sandy Phanor answers quick questions about her craft, discussing misconceptions about osteopathy, common conditions such as back pain, common causes of conditions, such as slouching, and how she enjoys treating spinal issues the most.
This episode provides timely coverage of the 2025 Meeting of the International Myeloma Society (IMS). Claudio Cerchione highlights the most important developments from the Annual Meeting, offers his reflections on the evolving treatment landscape, and discusses the role of research and collaboration in moving closer to a cure for myeloma.
Timestamps
00:00 – Introduction
02:08 – Reflections on his own career
04:20 – Claudio’s initial interest in the field
06:46 – Key takeaways from IMS 2025 Meeting
10:09 – Any potential gaps in coverage?
11:50 – How different patient groups are identified
13:30 – Minimal residual disease
16:15 – Impact of medical societies
20:24 – Translating new findings into clinical practice
23:44 – Improving the accessibility of treatments
26:45 – Claudio’s key takeaways from IMS 2025 Meeting
Disclaimer: The opinions expressed in this episode belong to the speakers and do not necessarily represent the opinions of EMJ.
This content was funded by AstraZeneca, and is intended for US Healthcare Professionals.
How do urologists, oncologists, and advanced practice providers coordinate care in muscle-invasive bladder cancer (MIBC)?
This AMJ podcast brings together three leading experts in each speciality to explore best practices in MDT collaboration, patient transitions, and treatment strategy.
Listen now to strengthen your approach to MIBC care.
Chapters:
- 00:00 – 02:18 | Introductions
- 02:18 – 10:15 | MDT Collaboration & Best Practices
- 10:15 – 16:16 | Patient Pathway & Coordination
- 16:16 – 25:23 | Treatment Decisions & Strategy
- 25:23 – 33:38 | Immune-Mediated AR Management
- 33:38 – 38:52 | Key Takeaways
Speakers:
Chandler Park, MD – Medical Oncologist, Norton Cancer Institute; & Clinical Faculty, University of Louisville School of Medicine
Gautam Jayram, MD – Urologist, Urology Associates, Nashville, TN
Michael White, PA-C – Physician Assistant, Urology Partners of North Texas
In the final episode, Jed Beitler reflects on leadership, mentorship, and the legacy of healthcare communications. From essential leadership qualities to the stories still untold, this conversation looks ahead at innovation, responsibility, and the next chapter in health communication.
Timestamps:
01:12 – Leadership qualities
04:03 – Mentoring
09:44 – Public education
13:57 – Legacy
What role does communication play in building health systems and addressing global health challenges? Jed Beitler discusses his work with non-governmental and international organisations, exploring lessons from Sub-Saharan Africa, strategies for fighting major diseases, and the importance of collaboration in global health.
Timestamps:
00:56 – Early career
02:37 – Sub-Saharan Africa
06:08 – Tackling HIV
07:53 – Not-for-profit organisations
11:43 – Diagnostics
This podcast explores the important aspects of healthcare professionals' practices in percutaneous coronary intervention treatment. It includes the role of adjunct therapies, a review of the updated guidelines, and real-world challenges in the treatment and management of acute coronary syndrome. The discussion focuses on expert opinions and real-world experiences, focusing on the current evidence and guidelines surrounding the efficacy and safety of antiplatelet agents, as well as the timing of their administration.
Disclaimers: This podcast discusses prescription-only medicines and is intended for healthcare professionals only. Please refer to prescribing information and adverse event reporting requirements in your country of practice. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Chiesi Farmaceutici or EMJ.
Timestamps:
00:55 – Healthcare evolution
02:40 – Global differences
05:44 – Industry shifts
09:07 – Perceptions of doctors
11:57 – Advice
In this rapid-fire episode, Jed Beitler answers quick questions about healthcare communications, from industry lessons and patient engagement to leadership advice and global health strategies. Perfect for listeners short on time but eager to gain decades of insight in just minutes.
How is extended reality transforming medical education? Rohan Jotwani discusses his work at Extended Reality Anesthesia Immersion Lab (XRAIL) and the role of immersive technology in training anesthesiologists and beyond. This episode highlights new tools, assessment methods, and challenges in scaling extended reality for education.
Timestamps:
00:43 – Education tools
04:55 – Measuring effectiveness
07:40 – Anesthesiology training
10:02 – Current challenges
12:37 – Clinician skepticism
In the final episode, Rohan Jotwani reflects on extended reality, AI, and other emerging therapies shaping tomorrow’s healthcare. From ethics and patient safety to neuromodulation, regenerative medicine, and research gaps, this episode envisions the next frontier in medical innovation.
Timestamps:
00:34 – Ethical considerations
02:34 – Chronic pain
04:40 – XR across medicine
06:44 – Pain management
In this episode of Onc Now, Luis Paz-Ares, Chair of the Medical Oncology Department at Hospital Universitario 12 de Octubre in Madrid, Spain, shares his expert insights on the evolving science of lung cancer. From the critical role of prevention and smoking cessation through to the latest therapeutic breakthroughs, Paz-Ares offers a candid discussion on the progress, challenges, and hopes for the future of lung cancer research and treatment.
Timestamps:
00:00 – Introduction
01:09 – Key insights on lung cancers
02:26 – Luis’s journey into oncology
04:10 – Highlights and lowlights of his role
08:30 – Delivering bad news to patients
10:30 – Current diagnosis process and treatment landscape
13:20 – Trends in lung cancer prevalence
16:00 – IMforte trial
21:15 – Biggest obstacles researchers and clinicians face today
22:50 – Non-smokers
24:40 – European Society for Medical Oncology (ESMO) 2025 predictions
26:00 – Luis’s three wishes for cancer research
Disclaimer: The opinions expressed in this episode belong to the speakers and do not necessarily represent the opinions of EMJ.
Rohan Jotwani explores how extended reality is reshaping pain management. From nerve retraining therapies to patient responses and clinical applications, this episode reveals how immersive environments are redefining how patients experience and manage pain.
Timestamps:
03:03 – Early career
05:45 – What is XR?
09:03 – Pain management
11:14 – Nerve retraining
14:51 – VR addictions
In this rapid-fire episode, Rohan Jotwani answers quick questions about extended reality in medicine, from its role in pain relief and rehabilitation to its future in training and patient care. Perfect for listeners who are short on time but eager to understand extended reality’s potential in just minutes.
In this inspiring episode of Hema Now, Catherine Glass speaks with Rob Pieters, Professor of Pediatric Oncology at Utrecht University; and co-founder of the Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands, the largest dedicated childhood cancer centre in Europe. Pieters shares his personal journey in paediatric oncology, the breakthroughs that have reshaped care, and the vision behind uniting all of the Netherlands’ childhood cancer expertise under one roof.
Timestamps
00:00 – Introduction
01:06 – Pieters’ start in paediatric oncology
01:29 – Biggest breakthroughs in childhood cancers
02:35 – Parts of Pieters work that bring him the most joy
03:12 - Lessons learnt from patients or their families
04:31 – The vision behind the Princess Máxima Center
08:35 – The impact of the Princess Máxima Center
10:53 – How is research funding divided?
12:55 – Evolution of treatments in paediatric oncology
15:10 – What will it take to achieve 100% cure rate in acute lymphoblastic leukaemia?
18:55 – President Elect of the European Society for Paediatric Oncology (SIOPE)
22:20 – One message of hope to families facing childhood cancer
25:10 – Pieter’s three wishes for healthcare
Pérez Marc discusses complementary RSV prevention strategies, including maternal vaccines and long-acting monoclonals. Learn about health system decision-making, cost-effectiveness, lessons from COVID-19, and the potential for RSV to become a vaccine-preventable disease.
Timestamps:
00:00 - Introduction
00:44 – RSV vaccine in routine antenatal care
04:22 – Dual strategy: vaccine and monoclonals
08:25 – Pandemic versus endemic
13:46 – Will RSV become vaccine-preventable?
15:02 – Final message for healthcare professionals
Maternal vaccination is a key tool in preventing RSV. Perez Marc discusses the BERNI study, its design, findings on safety and neonatal protection, real-world effectiveness, vaccine equity, ethical considerations, and global integration strategies.
Timestamps:
00:00 – Introduction
00:47 – Why maternal immunisation in RSV?
02:02 – The BERNI study
07:24 – The vaccine’s real-world impact
11:50 – Vaccine equity: a key challenge
12:57 – Ethical issues in maternal immunisation
In this first deep dive episode, Gonzalo Pérez Marc joins Saranya Ravindran to explore the global burden of RSV. Learn about hospitalisation and mortality rates, myths, seasonal changes, and long-term respiratory consequences. This episode highlights the urgent need for awareness and policy action in paediatric care.
Timestamps:
00:00 – Introduction
00:44 – Pérez Marc’s journey into RSV research
03:14 – Why RSV is not just a ‘common cold’
05:47 – Mortality in newborns and infants
06:55 – Why is RSV still underestimated?
09:51 – The impact of climate change
12:37 – RSV and long-term lung disease
15:01 – Pathophysiology of RSV
16:08 – Debunking RSV myths
In this quickfire episode, Gonzalo Pérez Marc answers key questions about RSV in infants, from overlooked risks and seasonality to public health priorities and maternal vaccine insights. Perfect for listeners short on time but eager to boost their RSV knowledge in just a few minutes.
In the final instalment, Stephanie Rutledge explores alcoholic hepatitis and long-term mental wellness. Covering acute clinical crises, experimental therapies, and future treatment guidelines, she highlights how hepatology can better integrate mental health and substance use care to transform patient outcomes.
Timestamps:
0:33 – Acute alcoholic hepatitis
3:08 – Patients with alcohol use disorder
4:32 – Medical advancements
6:25 – Prevention
10:45 – Current research
13:01 – Advice for young clinicians
What happens when alcohol use and metabolic factors collide? In Part 2, Stephanie Rutledge explains how alcohol-related liver disease develops, the challenges of holistic care, and the evolving role of liver transplantation. A must-listen for clinicians navigating the complexities of metabolic dysfunction and alcohol-related liver disease, and patient-centred management.
Timestamps:
0:21 – Metabolic dysfunction and alcohol-related liver disease (MetALD)
3:45 – Treatments for liver disease
5:49 – Mental health considerations
6:36 – Family support
7:51 – Factors beyond clinical treatment
Tolaney focuses on advancing breast cancer treatment through innovative clinical research. She has been instrumental in developing novel therapies and leading key clinical trials, particularly for early-stage HER2-positive breast cancer.
Timestamps
00:09 – Introduction
01:12 – What is HER2-positive breast cancer?
03:00 – Key trials Tolaney has led
07:16 – Antibody-drug conjugates
12:00 - Breast Oncology Guidelines
14:51 – Treatment optimisation
18:27 – Equity in healthcare
21:10 – Mentoring the next generation of oncologists
22:52 – Tolaney’s wishes for healthcare
Stephanie Rutledge joins host Saranya Ravindran to unpack the mental health dimensions of alcohol use disorder. From co-occurring conditions and behavioural strategies like motivational interviewing to the role of family and community support, this episode explores how integrated care can strengthen recovery.
Timestamps:
1:44 – Why hepatology
3:25 – Genetic factors
4:18 – Alcohol use disorder interventions
5:58 – Motivational interviewing
7:25 – Motivational interviewing skills
8:34 – Beyond clinical settings
10:49 – Alcohol use disorder therapy
In this rapid-fire episode, Stephanie Rutledge answers key questions on alcohol in hepatology, from mental health challenges in alcohol use disorder to transplant misconceptions, emerging therapies, and the impact of lifestyle changes like Dry January. It provides a concise, insightful overview in just minutes.
Timestamps:
1:08 – Treating alcohol use disorder
1:33 – Technique for alcohol use disorder recovery
1:50 – Misconceptions
2:14 – Psychosocial factors
2:32 – Alcohol use disorder and liver transplantation
2:50 – Experimental education
3:09 – Dry January and sober October
3:35 – Mental health
3:53 – Halting disease progression
4:14 – Liver transplantation
4:46 – Breakthrough therapies
This podcast and accompanying promotional content has been created in collaboration with and funded by Biogen. This information is intended for healthcare professionals. The presented content includes mentions of the Skyclarys▼ (omaveloxolone) EU-approved label.
Prescribing information for omaveloxolone can be found here.
Friedreich's ataxia (FA) is a rare genetic disease that can affect children and adults and cause progressive neurodegeneration, loss of physical function, multiple comorbidities, and even premature death.
In this episode, two well renowned experts, Dr Louise Corben and Dr Wolfgang Nachbauer discuss the diagnostic journey for patients with FA, disease progression and the importance of working with multidisciplinary teams in the development of management strategies.
In the final episode, Debby Bogaert discusses how cutting-edge microbiome science is being translated into practice. From novel vaccine approaches to strategies that support the developing microbiome, this conversation highlights how research can drive new preventive solutions to reduce pneumococcal disease and promote healthier lives for children everywhere.
0:30- Mucosal Vaccines
2:02 - Rotavirus Vaccine
2:49- Microbiome Science Policy
4:22- Ethics in Infant Microbiome
6:35- Final Message
In part two, Debby Bogaert unpacks her pioneering research on the infant respiratory microbiome. Discover how early microbial communities in the airways influence immunity, infection risk, and long-term respiratory health — and why nurturing the microbiome could play a critical role in disease prevention.
0:38- Microbiome and Resilience Against Infection
1:57- Microbiome in Healthy Infancy
3:00- Respiratory Microbiome and Inflammation
4:31- Benefits of Commensal Bacteria
6:39- Microbiome-Based Diagnostics
7:55- Pre and Post Biotics
10:03- Day-to-Day Practice
In this episode, host Jonathan Sackier is joined by Andrew Dunbar, Assistant Professor in the Department of Hematopoietic Biology and Malignancy at the University of Texas MD Anderson Cancer Center, Houston, USA. Dunbar discusses his research into myeloproliferative neoplasms, what drives disease progression and resistance, and promising targets for treatment, while reflecting on the mission of his lab and what lies ahead for the field.
Timestamps
00:00 – Introduction
02:29 – One thing people should know about myeloproliferative neoplasms
05:01 – Dunbar’s background and research focus
08:00 – What would Dunbar do if not science and medicine?
10:24 – The basics of myeloproliferative neoplasms
14:30 – Myeloproliferative neoplasm diagnosis and treatment
16:49 – What drives disease progression and resistance?
18:30 – The mission of Dunbar’s lab
21:23 – Development of AJ1-11095
22:54 – Balancing the complexity of disease modelling with urgent clinical needs
24:03 – Promising targets and pathways
26:35 – What’s on the horizon?
28:40 – Three wishes
In this first deep dive, Debby Bogaert explores the global burden of pneumococcal disease in young children and compares its impact with RSV and flu. She discusses how pneumococcus colonises the respiratory tract, the role of co-infections, and the importance of vaccination. Listeners will also learn how early life factors and microbiome recovery shape the infant respiratory ecosystem.
Timestamps:
0:42- Pneumococcus in Young Children 2:46- Global Burden of Pneumococcal Disease 4:15- Pneumococcus vs RSV and Flu 7:17- Microbiome Recovery 8:29- Pneumococcal Vaccination 9:46- Role of Co-Infections 11:34- Colonisation 13:30- Respiratory Tract As an Ecosystem 15:44- Early Life Factors
Get to know Debby Bogaert in this fast-paced quickfire round. She shares the most overlooked aspect of pneumococcal disease, clears up common misconceptions, and reveals the biggest surprise from her research. From advice for new parents to public health leaders, this bite-sized episode is packed with insights
Timestamps:
2:14- Overlooked aspect of pneumococcal disease
2:37- Infant Microbiome
2:50- One Misconception
3:04- Biggest Surprise
3:26- Message to New Parents
3:54- Advice to Public Health Leaders
In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways.
Timestamps:
00:00: Introduction
00:40: Mainstays of treatment
04:42: Limitations of current antifibrotics
07:50: The future of ILD personalised care
13:40: Are we close to the reversal of fibrosis?
15:52: A message for clinicians
In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways.
Timestamps:
00:00: Introduction
00:41: Challenges in early diagnosis
03:22: ILD biomarkers
05:49: The overlap with autoimmune diseases
09:16: AI in ILD detection
In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways.
Timestamps:
00:00: Introduction
02:00: ILD landscape: UK versus USA
04:33: What falls under the ILD umbrella?
06:38: Idiopathic pulmonary fibrosis
07:58: Understanding different patient profiles
09:28: Early clinical signs of ILD
In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways.
In this episode of Onc Now, host Jonathan Sackier welcomes Komal Jhaveri, Breast Medical Oncologist and clinical investigator at Memorial Sloan Kettering Cancer Center, New York, USA. Known for her trailblazing work in HER2-positive, HER2-low, and hormone receptor-positive breast cancers, Komal Jhaveri discusses how molecular subtyping, antibody-drug conjugates, and precision trials are reshaping the field.
Timestamps
00:00 – Introduction
02:50 – What initially drew Komal into oncology
04:45 – The future of breast cancer care
06:13 – Possibility of personalised treatments for patients
07:40 – Antibody-drug conjugates
09:30 – How we define HER2 status
14:40 – HER2-low disease
17:40 – Targeted therapy combinations
20:54 – Endocrine resistance
23:18 – The realities of implementing new therapies
28:40 – Promising initiatives on the horizon
31:30 – Komal's key takeaways
In the final episode of this series on preventative medicine, Vinod Patel discusses how integrated care models, professional training, and patient education improve diabetes outcomes. From chronic fatigue clinics to national screening programs, this episode highlights how innovation in education and collaboration can transform diabetes care across systems.
Timestamps:
00:40 – Clinical care
02:12 – Chronic Fatigue Clinic
03:52 – Lipid management
05:42 – DIGAMI protocol
07:14 – Retinopathy screening
08:45 – The future of care
12:25 – Teaching skills
What do retinal scans reveal about diabetes complications? In Part 2, Vinod Patel shares insights from his clinical research on diabetic retinopathy, including key risk factors, the impact of hypertension, and the future of screening using advanced imaging tools. A must-listen for clinicians and anyone curious about the eyes-diabetes connection.
Timestamps:
00:30 – Risk factors
02:17 – Drug treatments
03:01 – Retinal ischaemia
06:12 – Retinal imaging
Vinod Patel joins host Catherine Glass to explore how technology, early intervention, and integrated care are changing diabetes prevention. Learn about the ‘Alphabet Strategy’, machine learning in postpartum prediabetes prediction, and the growing role of glucagon-like peptide-1 (GLP-1) injectables. This episode unpacks how we can identify and reduce diabetes risk before complications begin.
00:36 – Alphabet Strategy
03:04 – Vascular complications
05:10 – Machine learning
09:09 – GLP-1 agonists
In this rapid-fire episode, Vinod Patel answers key questions about Type 2 diabetes, from early signs and screening frequency to emerging tech, common misconceptions, and lifestyle advice. Perfect for listeners short on time but eager to boost their diabetes knowledge in just 5 minutes.
In this episode, host Jonathan Sackier is joined by Emanuele Angelucci, Director of Hematology and Cellular Therapies and Director of the Stem Cell Transplant and Cellular Therapies Program at the Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Ospedale Policlinico San Martino Hospital in Genoa, Italy.
Timestamps
00:00 – Introduction 02:14 – The future of stem cell transplantation 03:15 – What continues to drive Emanuele in his work 05:40 – Donation of haematopoietic stem cells 10:00 – Gene therapy for haemoglobinopathies 11:40 – Will stem cell transplantation remain central in treating thalassaemia and sickle cell disease? 14:14 – Emanuele’s work on iron overload and toxicity 16:53 – Current landscape for haemoglobinopathies 22:11 – Key recommendations in the most recent clinical guidelines for haemoglobinopathies 25:00 – Promising developments on the horizon for patients with haemoglobinopathies 28:00 – Emanuele’s key takeaways
In this deeply personal episode, Jonathan Sackier speaks with Zoe Strickland, author of To Grief With Love, about how she navigated the loss of her son and found space for healing through creative expression and connection. They reflect on the evolving nature of grief, the importance of making space for sadness, and the small but powerful ways we can support ourselves and each other through loss. Zoe’s story is one of honesty, vulnerability, and hope, inviting listeners into a compassionate conversation about grief, meaning, and remembrance.
Timestamps
- (00:00) – Introduction
- (04:14) – Journalling and the birth of Doodle Lady
- (10:00) – Mindfulness and slowing down
- (15:20) – Helping others through shared experience
- (17:10) – Revisiting the five stages of grief
- (18:10) – A more fluid view: coping, learning, and growing
- (22:27) – Finding meaning through creativity and community
- (26:35) – The role of divinity in healing
- (30:47) – The Grief Room Door – honouring stillness
- (34:47) – Why time and space matter after loss
- (36:32) – The value of therapy and support
- (39:29) – Living with anniversaries
- (44:00) – Understanding suicide beyond labels
- (46:54) – Theory of Constraints and supporting prevention
- (51:26) – Finding resources and safe spaces
- (53:54) – A gentle closing reflection
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
0:47 - Acceptance and Commitment Therapy
3:17 - Anxiety and Chronic Pain
5:50 - ‘Let Them’ Concept
8:09 - David's Book
10:07 - Book Section Recommendations
11:20 - Lifestyle Factors
12:00 - Grief and Chronic Pain
14:06 - Delayed Reaction to Grief
In this episode, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
In this episode of Onc Now, host Jonathan Sackier is joined by Simon Lord, Associate Professor in Experimental Cancer Therapeutics, University of Oxford, UK, to discuss translating scientific breakthroughs into real-world treatments. With deep expertise in precision medicine and a passion for innovation in oncology, Lord brings a unique perspective on how the future of cancer therapy is being shaped today.
Timestamps 01:04 – Quickfire question
11:26 – Metabolic imaging
15:26 – Insulin resistance
18:04 – Patient-specific biology
20:35 – Tamoxifen risks
21:57 – Metabolic interventions
24:46 – Lifestyle changes
27:04 – Clinical trials
00:00 – Wishes for healthcare
This podcast has been funded by medac GmbH.
Disclaimer: The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of medac GmbH or EMJ. The speakers did not receive honoraria for the recording of this podcast.
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
Timestamps:
1:07 - Background
2:10 - Day to Day
3:21 - Why Pain Management
6:06 - Conversations About Pain
7:54 - Key Neurobiological Mechanisms
9:50 - Genetics
11:02 - Brain Mechanisms
11:32 - Biomarkers
In this series, host Catherine Glass speaks with David Cosio about the complex and often overlooked relationship between anxiety and chronic pain. They explore the neurobiological underpinnings of both conditions, how they influence each other, and what the future of integrated pain management may look like, from AI to psychedelics and beyond.
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Timestamps:
01:05 – Diagnostic workflows
03:58 – Non-invasive tools
05:37 – Right heart catheterisation values
09:05 – Vasoreactivity testing
11:10 – Genetic testing
13:08 – Innovative diagnostics
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Tinestamps:
00:45 – PAH management
03:05 – Hypoxia
06:42 – Decompensated PAH
10:06 – At-home treatments
12:44 – Multidisciplinary teams
14:50 – Novel therapies
In this episode of Onc Now, host Jonathan Sackier is joined by Stephen Freedland, Surgical Oncologist at Cedars-Sinai Medical Center, Los Angeles, California, USA, to discuss the intersections of biology, behaviour, and bias in prostate cancer. From diet and exercise to disparities in outcomes and promising data on enzalutamide, Freedland challenges assumptions and advocates for a more holistic, equitable approach to care.
Timestamps
01:20 – Background and clinical journey 02:39 – Cancer myths: what needs busting 03:22 – Lifestyle’s role in prostate cancer 05:18 – One habit all cancer patients should adopt 06:39 – Yes or No round 10:30 – Diet, obesity, and exercise: the data 13:25 – Mediterranean diet and outcomes 15:30 – Predictive lifestyle factors 16:19 – Racial disparities and root causes 18:35 – Gender-affirming treatment and prostate cancer in trans women 23:20 – Enzalutamide: latest data and developments 25:51 – Broader therapeutic landscape 28:40 – Risk of recurrence 30:19 – Advice for young oncologists 34:00 – Three wishes for the future of prostate cancer care
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
Timestamps:
Part 1:
01:00 – What is PAH
02:34 – Risk factors
04:21 – Misdiagnoses
07:13 – Pathophysiology
10:44 – World Symposium classification
In the second episode of our Rare Lung Diseases podcast mini-series, host Saranya Ravindran delves into the complexities of pulmonary arterial hypertension (PAH) with Neal Chaisson, Assistant Professor of Medicine at the Cleveland Clinic. Chaisson shares insights into why PAH remains under-recognised, the nuances of detection and diagnosis, and what the latest advancements mean for patients and clinicians. The discussion covers everything from early warning signs to future directions in PAH management and research.
In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care.
Timestamps:
1:20 - Current barriers to timely diagnosis
4:35 - How close are we to identifying all patients with Alpha 1?
5:20 - Role of consumer genomics in alpha detection
6:20 – Targeted testing amongst COPD patients
In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care.
Timestamps:
01:00 - Management of Alpha 1
03:30 - Augmentation therapy
05:50 - The discussion of neonatal screening for Alpha 1
08:00 - Evolving landscape
09:40 - Patients’ challenges with Alpha 1
11:20 - Closing comments on Alpha 1
In this episode, host Jonathan Sackier is joined by Steven Okoli, Honorary Senior Clinical Lecturer at Imperial College London. From leading the UK’s first adult stem cell transplant trial for sickle cell disease to driving innovation in AI-guided transfusion strategies, Okoli shares how clinical research, patient advocacy, and equity-driven care are reshaping the landscape of haemoglobinopathies in the UK and beyond.
Timestamps
00:00: Introduction
01:58: Quickfire round
09:09: Pioneering adult stem cell transplant in sickle cell
11:41: Combining AI and genetics for blood transfusion
13:58: Systemic disparities in sickle cell
20:58: Education and advocacy
23:30: Non-cancerous blood disorders
25:18: What’s next in sickle cell?
27:27: Okoli’s three wishes for healthcare
In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care.
In the first episode of our Rare Lung Diseases podcast series, host Saranya Ravindran speaks with James Stoller, Chief of Education and Pulmonary Physician at Cleveland Clinic, about Alpha-1 antitrypsin deficiency, a rare genetic condition that is frequently underdiagnosed. The discussion explores the complexities of Alpha 1, including current challenges in detection, advances in diagnosis and management, and what the future may hold for improving care.
Timestamps
00:56 – What is Alpha-1 antitrypsin deficiency?
01:45 – Mechanism of this genetic disorder
03:12 – What makes Alpha 1 so hard to spot?
04:30 – Genetic complexities of Alpha 1
06:00 – Risk factors
In this episode of Onc Now, host Jonathan Sackier is joined by Jean Abraham, Professor of Precision Breast Cancer Medicine at the University of Cambridge, to delve into the future of integrated cancer medicine, the evolving role of clinical trials, and how precision oncology is redefining outcomes for patients with breast cancer across the UK.
Timestamps
00:00 – Introduction
01:28 – Quickfire round
09:50 – Cambridge institutes for precision medicine
12:53 – Predictive/prognostic tools in breast cancer
15:33 – The future of breast cancer clinical trials
18:34 – Integrating genomic data
22:31 – Addressing cost barriers
24:22 – How AI is transforming breast cancer care
28:08 – Why oncology?
30:04 – A message to non-oncologists
31:54 – Abraham’s three wishes for healthcare
In this episode, Jonathan Sackier welcomes Claudio Cerchione, haematologist and researcher at the Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy. From his early interest in plasma cell disorders, Cerchione shares key insights into the evolution of multiple myeloma (MM) research, the rising role of minimal residual disease (MRD), and promising developments in monoclonal antibodies and CAR-T therapy. He also reflects on standout moments from recent European Hematology Association (EHA) Congress and American Society of Clinical Oncology (ASCO) Annual Meeting, and shares his hopes for the future of haematology.
Timestamps:
-
2:14: Memorable career experiences for Claudio
-
4:20 Biggest breakthrough in MM
-
5:10 Interest in plasma cell disorders
-
6:30 A surprising fact about multiple myeloma
-
7:40 Claudio’s top choice for a dinner party guest
-
10:30 The importance of MRD in haematology
-
13:00 Monoclonal antibodies and CAR-T therapies
-
19:00 Current challenges
-
22:22 Claudio’s key EHA and ASCO takeaways
-
28:30 Claudio’s three magic wishes
In this three-part series, Jonathan Sackier sits down with Professor Zoë Paskins to explore the complexities and advancements in rheumatology and bone health. From her personal journey into the field, to innovations in managing osteoporosis and arthritis, Zoë offers compelling insights into the current landscape and future of musculoskeletal care.
Timestamps:
01:03 - Tools to improve underdiagnosis & management of osteoporosis
04:04 - Psychological impact of musculoskeletal conditions
08:50 - What’s new for arthritis management?
13:40 - Successes and challenges of the Fracture Liaison Service
16:45 - Potential of social media in sharing knowledge
20:00 - Zoë’s three wishes for healthcare
In this three-part series, Jonathan Sackier sits down with Professor Zoë Paskins to explore the complexities and advancements in rheumatology and bone health. From her personal journey into the field to innovations in managing osteoporosis and arthritis, Zoë offers compelling insights into the current landscape and future of musculoskeletal care.
Timestamps:
0:25 - What’s new in osteoporosis management?
5:05 - Key challenges in addressing gaps in care
In this three-part series, Jonathan Sackier sits down with Professor Zoë Paskins to explore the complexities and advancements in rheumatology and bone health. From her personal journey into the field, to innovations in managing osteoporosis and arthritis, Zoë offers compelling insights into the current landscape and future of musculoskeletal care.
Timestamps:
00:00 - Introduction
03:45 - Zoë’s start in rheumatology and what keeps her passionate
06:27 - Shared decision-making in rheumatology
12:30 - How should we be screening for osteoporosis?
In this episode of Hema Now, host Jonathan Sackier is joined by Kevin Rouault-Pierre and Onima Chowdhury, to explore the biological mechanisms behind MDS, with a spotlight on SF3B1 mutations. From epigenetic stress to diagnostic strategies, this discussion bridges laboratory research and frontline care.
Timestamps 01:11 – Quickfire Round 07:11 – Haematology Misconceptions 10:56 – Understanding MDS 18:42 – Treating Myeloid Malignancies 23:20 – Epigenetic Mechanisms 28:30 – MDS Treatment Approaches 34:56 – Three Wishes
Carbon Emissions in Medicine
In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men’s health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology.
Timestamps:
0:30 – The carbon footprint of patient travel 2:05 – How climate change affects urological health 5:46 – Practical advice for urologists 7:53 – MRI-targeted prostate biopsies 10:40 – Emissions associated with MRI procedures
Plant-Based Diets
In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men’s health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology.
0:19 – The connection between diet and health 4:05 – Organic versus non-organic: does it matter? 4:56 – Plant-based diets and improved erectile function 7:19 – Stigma and undertreatment in men’s health 9:14 – Research from the Prostate Cancer Foundation 11:57 – The growing role of lifestyle medicine 14:49 – Glucagon-like peptide-1 (GLP-1) agonists in urological health
This episode offers insights into the lived experience of patients with Becker Muscular Dystrophy (BMD). Mike Voto, a patient advocate for BMD, shares his story and discusses the personal challenges around diagnosis, disease progression and the impact of living with BMD.
Microplastics
In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men’s health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology.
Timestamps: 1:01 – Getting into urology 1:52 – Pioneering environmental health in urology 2:28 – Patient perspectives on plastic exposure 4:25 – Microplastics in testicular tissue 7:06 – Plastics are everywhere 9:30 – Immune response to microplastics 10:20 – Microplastics in female genitalia and sanitary product
In this series, the host Catherine Glass welcomes Stacy Loeb, a renowned urologist and lifestyle medicine advocate, to explore the growing impact of environmental factors on men’s health. From the risks of microplastics and the benefits of plant-based diets to the carbon cost of prostate procedures, these conversations challenge conventional clinical perspectives and offer practical, planet-conscious solutions for modern urology.
In the third episode of our lung cancer miniseries, Jonathan Sackier is joined by Douglas E. Wood, Henry N. Harkins Professor and Chair of Surgery at the University of Washington. A global leader in thoracic oncology, Wood explores the critical role of lung cancer staging, the evolution of screening guidelines, and how surgical innovation is shaping the future of lung cancer treatment.
Timestamps:
00:00 – Introduction
02:37 – Career beginnings
07:37 – Career highlights
11:38 – Thoracic oncology guidelines
15:26 – AI and big data
17:17 – Expanding lung cancer screening
19:29 – Robotic surgery
23:38 – Targeted therapies
27:23 – Cancer staging
30:44 – Lung volume reduction surgery
35:10 – Current trials
40:50 – Three wishes for healthcare
In this special episode of Onc Now, host Jonathan Sackier is joined by Lennard Lee, Associate Professor of Cancer Vaccines at the University of Oxford, to explore the promise of personalised cancer vaccines, the power of data science and AI in cancer care, and the national initiatives bringing these innovations to patients.
Timestamps
02:01 – Quickfire intro 07:21 – COVID Cancer Programme 11:32 – Cancer vaccine potential 15:56 – Vaccine trial insights 16:58 – Data science and AI 24:10 – Positivity in practice 26:48 – Public health innovation 29:11 – Vaccine hesitancy 33:56 – Final takeaway
Robotic revolution in reproductive surgery.
In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women’s health through the eyes of a pioneering clinician and researcher.
Timestamps:
00:20 – What’s next in gynaecologic robotic surgery?
06:46 – Falcone’s pioneering research
16:44 – Three wishes for healthcare
Innovations in the treatment of endometriosis and adenomyosis
In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women’s health through the eyes of a pioneering clinician and researcher.
Timestamps:
00:00 – Barriers to early endometriosis detection
09:16 – Treating adenomyosis and fertility impact
12:10 – Global health innovation in emerging markets
16:05 – The first uterus transplant
Lydia Scarfò is a Physician Scientist at the B-cell Neoplasia Unit and an Assistant Professor at Università Vita-Salute San Raffaele, Milan, Italy.
She is involved in both clinical and pre-clinical studies, including being a co-investigator in over 20 clinical trials in haematological malignancies, including chronic lymphocytic leukaemia.
Timestamps:
0:00 – Introduction
1:14 – Quickfire questions
7:31 – Haematology inspiration
9:08 – STIL loss
11:42 – Splenic marginal zone lymphoma
13:03 – Novel targeted therapies for chronic lymphocytic leukaemia
17:35 – Covalent BTK inhibitors
19:30 – Chemo-free approach for hairy cell leukaemia
22:20 – Recent advances, challenges, and opportunities
25:58 – Three wishes
Global Perspectives and Leadership in Gynaecology
In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women’s health through the eyes of a pioneering clinician and researcher.
Timestamps:
00:00 – Comparing gynaecology globally
03:20 – The evolution of endometriosis research
05:30 – Breakthroughs and hopes for a cure
In this episode, the host Saranya Ravindran speaks with Tommaso Falcone about transformative developments in reproductive health, including the evolution of endometriosis research, the promise of robotic surgery, and the global expansion of gynaecologic care. From debunking myths about fertility to reflecting on cross-continental medical practice, this episode explores the future of women’s health through the eyes of a pioneering clinician and researcher.
Timestamps:
00:00 – Introduction
01:05 – Quickfire round
05:12 – ‘Yes or no’ segment
This episode offers expert insights Dr. Aravindhan Veerapandiyan, MD. Exploring Becker Muscular Dystrophy (BMD), covering early signs, diagnostic challenges, disease progression, and current management approaches. It also explores care transitions, multidisciplinary involvement, and unmet needs in the BMD care landscape.
In this second episode of our lung cancer miniseries, Jonathan Sackier is joined by David Baldwin, a leading expert in screening, epidemiology, and policy. Baldwin reflects on national screening programmes, groundbreaking trials, and how AI, big data, and evidence-based guidelines are reshaping lung cancer care.
Timestamps:
00:00 – Introduction
03:17 – Key takeaways from the UKLS trial
11:10 – Boosting participation in screening studies
17:04 – The Targeted Lung Health Check programme
23:30 – Understanding large datasets in lung cancer epidemiology
32:44 – AI and big data in lung cancer imaging
41:43 – Shaping national guidelines
47:47 – Are we doing enough to prevent lung cancer?
53:06 – Baldwin’s three wishes for healthcare
In the second part of this special episode of Onc Now, Jonathan Sackier continues his thrilling conversation with Bradley Monk, a leading gynaecologic oncologist, with an in-depth discussion of the DUO-E trial, Monk’s most impactful Society of Gynecologic Oncology (SGO) insights, and the integration of AI into the clinic.
Timestamps:
00:00 – Introduction
00:40 – Quickfire questions
06:19 – Inspiration
08:31 – Molecular basis of cancer treatment
12:12 – DUO-E trial design
14:12 – Barriers to 4-drug regimen approval and access
20:01 – Most impactful SGO insights
21:10 – AI integration
24:03 – Three wishes
26:30 – Outro
In the third and final episode of our miniseries on infectious disease diagnostics, Jonathan sits down with global diagnostics leader Rosanna Peeling, Professor and Chair of Diagnostics Research at the London School of Hygiene and Tropical Medicine. Together, they explore the life-saving role of diagnostics in global health, from battling STDs to confronting COVID-19, and examine how equitable access, social innovation, and regulatory reform can transform disease control and pandemic preparedness.
Timestamps:
00:00 – Introduction
06:09 – Rosanna’s interest in microbiology
08:12 – The IDC’s work
10:52 – Funding for diagnostics
13:30 – Diagnostic testing in low-resource settings
18:21 – Chlamydia research
24:19 – Regulatory approval challenges
29:35 – Social innovation
34:08 – Clinician adaptation
37:10 – Current diagnostic innovations
40:30 – Rosana’s three wishes for healthcare
Rafael Fonseca is a distinguished Haematologist at Mayo Clinic, specialising in multiple myeloma and related plasma cell disorders. He earned his medical degree at Universidad Anáhuac in Mexico, and went on to complete his residency in Internal Medicine at the University of Miami, Florida, USA followed by a Hematology and Oncology fellowship at Mayo Clinic in Rochester, Minnesota, USA.
Timestamps
01:44 – Quickfire questions
07:25 – CAR-T cell therapy
10:48 – Anti-CD38 antibodies
13:31 – Minimal residual disease
14:30 – Bispecific antibodies
15:31 – Antibody-drug conjugates
19:04 – ASCO 2025
21:24 – Genetic discoveries
26:28 – Fonseca’s three wishes
In this episode, Jonathan Sackier kicks off a special miniseries on lung cancer with Haval Balata, Consultant Respiratory Physician at Manchester University NHS Foundation Trust. From the Manchester Lung Health Check to robotic bronchoscopy, Balata shares insights into pioneering early detection efforts, the challenge of public misconceptions, and innovations reshaping lung cancer screening and diagnosis.
Timestamps:
03:12 – Inspiration to specialise 04:09 – Early diagnosis barriers 08:02 – Manchester Lung Health Check 14:10 – Robot-assisted bronchoscopy 19:24 – Public misconceptions 28:57 – Risk stratification & follow-up 34:24 – Innovations in early detection 37:10 – Hopes for the future 41:22 – Three healthcare wishes
In this two-part series host Jonathan Sackier is joined by Bradley Monk, a pioneering figure in gynaecologic oncology. In Part 1, they discuss key updates from the European Society of Gynaecological Oncology (ESGO) Congress, including the updated ESGO-ESTRO-ESP endometrial cancer guidelines and the latest results from the KEYLYNK-001 study in ovarian cancer. With reflections from his three-decade career, Monk provides actionable takeaways for clinicians and researchers alike. Stay tuned for Part 2, where they delve into insights from SGO 2025.
Timestamps:
00:00 - Quickfire questions 04:55 - Career milestones 07:10 - ESGO 2025 standout sessions 09:52 - KEYLYNK-001 trial & takeaways 13:52 - New endometrial cancer staging
In this bonus episode, join EMJ host Dr Hannah Moir as she speaks with our two urological experts, Dr Todd Linsenmeyer and Dr Chris Harding. They discuss recent advances in day-to-day technologies for intermittent catheterisation, covering innovations and advancements in catheter technology aimed at improving the user experience.
In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice.
Timestamps:
1:12 – A typical consultation
7:50 – Advice for clinicians
In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice.
Timestamps:
0:14 – The power of hope for patients 1:08 – Opening her own practice
In this three-part series, Jonathan Sackier sits down with Isabelle Amigues, rheumatologist and founder of UnabridgedMD, a direct rheumatology practice in Denver, Colorado, USA. Together, they discuss the importance of hope in patient care and the inspiration behind starting her own practice.
Timestamp:
2:27 – The origins of ‘Hope Driven by Science’
In this episode of Hema Now, host Jonathan Sackier is joined by Paolo Gallipoli, Clinical Reader at the Centre for Haemato-Oncology at Barts Cancer Institute, to break down the biology, onset, and treatment of myeloid leukaemias. They detail common misconceptions about myeloid leukaemias, explain the differences between chronic myeloid leukaemia and acute myeloid leukaemia, and discuss Gallipoli’s own research in the field, with a view towards future developments.
Timestamps
01:34 – Quickfire questions
06:55 – Potential careers
08:43 – Common misconceptions
11:34 – Best advice received
13:43 – Adaptive metabolic changes
16:45 – Chronic myeloid leukaemia vs acute myeloid leukaemia
19:20 – Recent publication
22:55 – Clonal hematopoiesis
27:13 – Treatment obstacles
29:18 – Future developments
31:01 – Gallipoli’s three wishes
In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care.
01:47 – Interstitial Lung Disease
08:25 – Evolution of Rheumatology
11:39 – Wishes for Healthcare
In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care
01:49 – Polymyalgia Rheumatica
05:59 – Vascular Ultrasound
09:11 – Immune Ageing
In this three-part series, Jonathan Sackier sits down with Richard Conway, rheumatologist, researcher, and educator. Together, they delve into cutting-edge insights on polymyalgia rheumatica, immune ageing, and the future of rheumatology care.
00:22 – Mortality Patterns
08:57 – JAK Inhibitors
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Joan Carles, Head of Section for the Genitourinary, Central Nervous System, Sarcomas and Tumours of Unknown Origin Unit at Vall d’Hebron University Hospital. Carles discusses breakthroughs in genitourinary cancer and sarcoma treatment, including anti-angiogenic therapies, overcoming resistance, and the role of genetic polymorphisms in personalised medicine.
Timestamps:
00:00 – Introduction
01:56 – Anti-angiogenic therapies
05:03 – Treatment resistance
07:53 – Genetic polymorphisms
09:02 – Sarcoma treatments
11:16 – Novel drugs
15:22 – Oncology societies
18:00 – Carles’ three wishes for healthcare
Join us for this two-episode mini-series featuring lead study authors, Mario Castro and Njira Lugogo, as they discuss key findings from the VESTIGE trial and their implications on asthma care.
Uncover:
· The importance of patient phenotyping: How can biomarkers and imaging improve asthma management?
· Mucus plugging and airflow obstruction: What does the latest research reveal?
· Biologics and airway remodeling: What did the VESTIGE trial reveal about biologics and airway remodeling?
· The role of imaging in clinical practice: How can CT scans provide new insights into asthma care?
Speakers
Mario Castro, University of Kansas School of Medicine, United States
Njira Lugogo, University of Michigan, Ann Arbor, Michigan, United States
Disclaimers:
· This program is non-promotional and is sponsored by Sanofi and Regeneron Pharmaceuticals, Inc.
· The speakers are being compensated and/or receiving an honorarium from Sanofi and Regeneron in connection with this program
· The content contained in this program was jointly developed by AMJ, the speakers, and Sanofi and Regeneron, and is not eligible for continuing medical education (CME) credits
· See full US Prescribing Information for dupilumab
· MAT-US-2412937 v2.0 - Pro1 Expiration Date: 04/21/2026
Speaker disclosures:
· MC reports research support from the American Lung Association, AstraZeneca, Gala Therapeutics, Genentech, GSK, NIH, Novartis, PCORI, Pulmatrix, sanofi-aventis, Shionogi, and Theravance Biopharma, consultancy fees from Allakos, Amgen, Arrowhead Pharmaceuticals, Blueprint Medicines, Connect BioPharma, Genentech, GSK, Merck, Novartis, OM Pharma, Pfizer, Pioneering Medicines, sanofi-aventis, Teva, Third Rock Ventures, and Verona Pharmaceuticals, speaker fees from Amgen, AstraZeneca, Regeneron Pharmaceuticals Inc., and Sanofi, and royalties from Aer Therapeutics.
· NLL reports research support paid to institution from Amgen, AstraZeneca, Avillion, Genentech, Gossamer Bio, GSK, Regeneron Pharmaceuticals Inc., Sanofi, and Teva, consultancy fees from and participation on advisory boards with Amgen, AstraZeneca, Genentech, GSK, Novartis, Regeneron Pharmaceuticals Inc., Sanofi, and Teva, travel support from AstraZeneca, and honoraria for non-speaker bureau presentations from AstraZeneca and GSK.
References:
- Castro M et al. Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial. Lancet Respir Med. 2025;13:208-20. doi: 10.1016/S2213-2600(24)00362-X.
Join us for this two-episode mini-series featuring lead study authors, Mario Castro and Njira Lugogo, as they discuss key findings from the VESTIGE trial and their implications on asthma care.
Uncover:
· The importance of patient phenotyping: How can biomarkers and imaging improve asthma management?
· Mucus plugging and airflow obstruction: What does the latest research reveal?
· Biologics and airway remodeling: What did the VESTIGE trial reveal about biologics and airway remodeling?
· The role of imaging in clinical practice: How can CT scans provide new insights into asthma care?
Speakers
Mario Castro, University of Kansas School of Medicine, United States
Njira Lugogo, University of Michigan, Ann Arbor, Michigan, United States
Disclaimers:
· This program is non-promotional and is sponsored by Sanofi and Regeneron Pharmaceuticals, Inc.
· The speakers are being compensated and/or receiving an honorarium from Sanofi and Regeneron in connection with this program
· The content contained in this program was jointly developed by AMJ, the speakers, and Sanofi and Regeneron, and is not eligible for continuing medical education (CME) credits
· See full US Prescribing Information for dupilumab
· MAT-US-2412937 v2.0 - Pro1 Expiration Date: 04/21/2026
Speaker disclosures:
· MC reports research support from the American Lung Association, AstraZeneca, Gala Therapeutics, Genentech, GSK, NIH, Novartis, PCORI, Pulmatrix, sanofi-aventis, Shionogi, and Theravance Biopharma, consultancy fees from Allakos, Amgen, Arrowhead Pharmaceuticals, Blueprint Medicines, Connect BioPharma, Genentech, GSK, Merck, Novartis, OM Pharma, Pfizer, Pioneering Medicines, sanofi-aventis, Teva, Third Rock Ventures, and Verona Pharmaceuticals, speaker fees from Amgen, AstraZeneca, Regeneron Pharmaceuticals Inc., and Sanofi, and royalties from Aer Therapeutics.
· NLL reports research support paid to institution from Amgen, AstraZeneca, Avillion, Genentech, Gossamer Bio, GSK, Regeneron Pharmaceuticals Inc., Sanofi, and Teva, consultancy fees from and participation on advisory boards with Amgen, AstraZeneca, Genentech, GSK, Novartis, Regeneron Pharmaceuticals Inc., Sanofi, and Teva, travel support from AstraZeneca, and honoraria for non-speaker bureau presentations from AstraZeneca and GSK.
References:
- Castro M et al. Effect of dupilumab on exhaled nitric oxide, mucus plugs, and functional respiratory imaging in patients with type 2 asthma (VESTIGE): a randomised, double-blind, placebo-controlled, phase 4 trial. Lancet Respir Med. 2025;13:208-20. doi: 10.1016/S2213-2600(24)00362-X.
In this three-part series, Jonathan Sackier is joined by Rini Chatterjee, clinician, longevity expert, and Founder of Resilience Health. Together, they explore how functional medicine, biohacking, and evolutionary biology can be used to transform modern health care, improve health span, and prevent chronic disease.
Timestamps: 00:00 – Healthtech innovation 03:02 – Biohacking’s future 09:20 – Three healthcare wishes
In this three-part series, Jonathan Sackier is joined by Rini Chatterjee, clinician, longevity expert, and Founder of Resilience Health. Together, they explore how functional medicine, biohacking, and evolutionary biology can be used to transform modern health care, improve health span, and prevent chronic disease.
Timestamps: 00:00 – Resilience Health’s impact 04:30 – Gut–brain connection 12:00 – Immune optimisation
In this three-part series, Jonathan Sackier is joined by Rini Chatterjee, clinician, longevity expert, and Founder of Resilience Health. Together, they explore how functional medicine, biohacking, and evolutionary biology can be used to transform modern health care, improve health span, and prevent chronic disease.
Timestamps:
02:00 – Career evolution 06:45 – Holistic medicine explained
In this episode of Hema Now, Diu Nguyen joins Jonathan Sackier to discuss breakthroughs in acute myeloid leukaemia (AML) research. From RNA-binding proteins to the future of stem cell-targeted therapies, Nguyen shares the translational goals of her lab and what’s on the horizon in AML diagnosis and treatment.
Timestamps:
01:20 – Quickfire Insights
03:32 – AML Breakthroughs
04:47 – Leukaemia Surprise
06:42 – Alternate Pathways
07:54 – RNA Differences
12:08 – Diagnostics Future
14:03 – RBMX Spotlight
20:21 – Targeted Therapies
27:07 – Treatment Barriers
31:32 – Three Wishes
This episode explores the treatment of patients with intermediate-risk non-muscle-invasive bladder cancer (IR NMIBC), an important topic in urology today. Expert in the field, Marco Moschini, delves into the topic of risk-adapted treatment, where patients are assigned to a particular risk group based on patient- and tumour-related factors, also taking into account the prior treatment history and the timing of recurrences.
Topics discussed include:
- Current confusion about the clinical heterogeneity within the intermediate-risk patient group
- The best way to select adequate intravesical therapy for this group
- The lack of consensus regarding an optimal schedule for adjuvant intravesical chemotherapy
*References
- Scilipoti P, et al. Urol Oncol. 2024;42(12):451.e1-451.e10. PMID: 39060208.
- European Association of Urology. EAU NMIBC Risk Calculator, https://nmibc.net/
- Sylvester RJ, et al. Eur Urol. 2021;79(4):480-488. PMID: 33419683.
- Tan WS, et al. Eur Urol Oncol. 2022;5(5):505-516. PMID: 35718695.
- Gontero P, et al. EAU Guidelines on Non-muscle invasive Bladder Cancer (TaT1 and CIS), Limited Update March 2025. European Association of Urology Guidelines Office, Arnhem, The Netherlands, 2025. Full Guideline
- Friedrich MG et al. Eur Urol. 2007;DOI:10.1016/j.eururo.2007.02.063.
This is a non-promotional podcast funded and developed by AbbVie for healthcare professionals only. The content of this podcast is correct at the time of recording, which is December 2024. The views expressed in this podcast are those of the individual speakers and do not necessarily reflect the view of AbbVie or EMJ
If you are listening to this podcast through a podcast app, please note that any advertisements you may hear are not affiliated with this podcast or AbbVie in any way. To stop receiving podcast notifications, please unsubscribe from this series in your podcast player.
The Post-Stroke Spasticity Classification System was created and funded by AbbVie with the assistance of a group of international experts in the field of Post-Stroke Spasticity, utilising both published risk factors and their own clinical experience.
BONT-AA-00049-MC April 2025
In this three-part series, Jonathan Sackier speaks with Peder Langeland Myhre about cutting-edge advancements in heart failure research, the importance of biomarker-driven care, the challenges of implementing digital health tools globally, and how Norway is reshaping participation in cardiology clinical trials.
Timestamps:
00:17 – Digital health equity
06:00 – Podcasts in medicine
07:59 – Three cardiology wishes
In this three-part series, Jonathan Sackier speaks with Peder Langeland Myhre about cutting-edge advancements in heart failure research, the importance of biomarker-driven care, the challenges of implementing digital health tools globally, and how Norway is reshaping participation in cardiology clinical trials.
Timestamps:
00:21 – Biomarker disparities
04:52 – Norway trial challenges
07:15 – Boosting trial engagement
In this three-part series, Jonathan Sackier speaks with Peder Langeland Myhre about cutting-edge advancements in heart failure research, the importance of biomarker-driven care, the challenges of implementing digital health tools globally, and how Norway is reshaping participation in cardiology clinical trials.
Timestamps:
02:06 – Skiing & heart
04:02 – Blix award impact
07:51 – Heart failure biomarkers
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Janice Walshe, Consultant Medical Oncologist at St Vincent’s University Hospital, Dublin, Ireland. They explore the economic realities of cancer diagnostics, fertility preservation in patients with breast cancer, and the impact of international collaboration on the future of clinical trials.
Timestamps:
00:00 – Introduction
03:25 – Economic disparities and oncology care in Ireland
07:20 – Neoadjuvant therapy for HER2-positive breast cancer
10:13 – Spotlight on invasive lobular carcinoma
12:36 – Fertility preservation in breast cancer
15:20 – Menopause after cancer
19:09 – The latest clinical trials in Ireland
21:50 – International trials and research projects
23:50 – Walshe’s three wishes for healthcare
In this episode of Hema Now, Jonathan Sackier is joined by John Riches, Clinical Reader in Cancer Immunometabolism at the Barts Cancer Institute and Honorary Consultant Haemato-oncologist. They explore how metabolic shifts drive lymphoma progression, the potential of immunotherapy, and what the future holds for treating lymphoid malignancies.
Timestamps:
00:00 – Introduction
01:46 – Riches’ journey into haematology
03:42 – What is T cell exhaustion?
07:06 – The key role of metabolism in lymphoma
09:33 - Richter’s syndrome
13:17 – Breakthroughs in immunotherapy
20:27 – The challenges of translational research
25:39 – B cells in autoimmune diseases
28:16 – The potential of breath biopsy
32:58 – Riches' three wishes for healthcare
In the second episode of our miniseries on infectious disease diagnostics, Jonathan is joined by molecular epidemiologist Rodney Rohde, Regents’ Professor at Texas State University, USA. Together, they explore diagnostic innovations in the fight against antimicrobial resistance, gaps in zoonotic disease detection, and the persistent challenge of vaccine hesitancy.
Timestamps:
00:00 – Introduction
01:45 – Breakthroughs in molecular diagnostics
08:30 – Diagnostic tools to combat superbugs
14:18 – Can bacteriophages replace antibiotics?
19:04 – Controlling rabies and hantavirus
28:33 – Diagnostic successes and failures from COVID-19
35:22 – How do we address vaccine hesitancy?
44:10 – Preparing for the next pandemic
47:03 – Rohde's three wishes for healthcare
In this episode, Jonathan Sackier is joined by Philip Hamann, Consultant Rheumatologist at North Bristol NHS Trust, UK. Known for his engaging TEDx talks and innovative work with AI-driven healthcare apps, Hamann discusses how big data, personalised medicine, and a holistic approach are revolutionising care for patients with rheumatoid arthritis.
Timestamps:
00:00 – Introduction
01:01 – Using humour to communicate science
06:02 – ‘Living with Rheumatoid Arthritis’: Hamann’s award-winning app
14:43 – The cost of personalised medicine
19:07 – Real-world use of the app
26:05 – Importance of real-time data in rheumatology
33:10 – What does holistic care really mean?
40:07 – Hamann’s three wishes for healthcare
In this episode, host Jonathan Sackier speaks with Alexander Spira about cutting-edge advances in lung and colorectal cancer, including EGFR and KRAS-targeted therapies. They also discuss Spira’s leadership in oncology research, his thoughts on the evolving ‘town-gown’ dynamic in US medicine, and his hopes for the future of cancer care.
Timestamps: 00:00 – Introduction 01:50 – Most memorable family travel adventure 03:30 – What inspired you to go into oncology 05:49 – Three recent publications in lung cancer 07:02 – Real-world data on colorectal cancer 08:15 – Sex/gender differences in non-small cell lung cancer 11:53 – The science of KRAS mutations and drug development 15:07 – Accelerating diagnostics and access to therapies 17:13 – The ‘town-gown’ debate in American healthcare
18:09- Three Wishes
In this episode, Jonathan Sackier is joined by Adrian Owen, Professor of Cognitive Neuroscience and Imaging at the University of Western Ontario. They explore Owen’s groundbreaking research on consciousness in vegetative states, the ethical questions raised by his work, and the cutting-edge technology that has changed our understanding of the brain.
Timestamps:
00:00 – Introduction
02:46 – Taking one album on a desert island
04:03 – A groundbreaking discovery about vegetative states
06:58 – Owen’s bestseller: ‘Into the Gray Zone’
11:18 – Where is the border between life and death?
15:40 – Cutting-edge technologies for brain imaging
20:11 – Applications of fMRI and EEG
24:41 – Does brain-training work?
31:09 – Implications for life support and end-of-life care
36:00 – Owen’s three wishes for healthcare
This week, Jonathan is joined by Shaji Kumar, an expert in hematology and oncology, particularly multiple myeloma, who has made significant contributions to both clinical and translational science.
Timestamps:
(00:00) – Introduction
(02:23) – Drug combinations and myeloma biology
(08:34) – Treating newly diagnosed multiple myeloma
(17:24) – Quadruplet regimens
(23:09) – Clinical trials for plasma cell malignancies
(28:04) – The bone marrow microenvironment in multiple myeloma
(30:29) – “Blind men and an elephant”
(33:58) – Kumar’s three wishes for healthcare
This podcast series was sponsored by Theramex UK who had no input in the content which was developed by EMJ.
The speakers were selected by Theramex and received honorarium. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Theramex or EMJ. Please refer to local marketing authorisation and prescribing practices for guidance.
The Effect of HRT on Brain Function and Mental Health. - Episode 3 - Brain health expert Rossella Nappi joins Hannah Moir to discuss the effect of MHT on brain function and mental health.
In this podcast series, we focus on women's health and the impact of menopause. Our experts explore the role and long-term impact of menopausal hormone therapy (MHT), otherwise referred to as hormone replacement therapy (HRT), on our heart, bones, and brain.
In this episode of the EMJ Podcast, Jonathan Sackier sits down with Jose Alexander, Clinical Microbiologist and Director of Microbiology at AdventHealth Orlando, to explore the cutting edge of infectious disease diagnostics. From next-generation sequencing to rapid tests for brain-eating amoeba, Alexander shares insights into the latest innovations shaping the field, the fight against antimicrobial resistance, and the future of microbiology diagnostics.
Timestamps:
00:00 – Introduction
03:55 – Alexander’s introduction to microbiology
05:42 – Developing a rapid test for a brain-eating amoeba
09:40 – Where is this amoeba found?
12:13 – Next-generation sequencing in infectious disease
14:36 – Streptococcus pneumoniae serotype/genotype service
17:06 – Vaccine hesitancy
19:03 – Antimicrobial resistance
22:02 – The discovery of a novel variant of Klebsiella pneumoniae
24:32 – The clinical use of bacteriophages
27:01 – The future of the field
28:41 – Alexander’s three wishes for healthcare
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Stephen Chan, Clinical Professor at the Department of Clinical Oncology of the Chinese University of Hong Kong, to discuss groundbreaking trials in hepatobiliary cancers, the role of diet in chronic liver disease, and the future of liver cancer care.
Timestamps:
00:00 – Introduction
02:09 – CARES-310 trial for liver cancer
4:33 – Camrelizumab + rivoceranib versus sorafenib
7:07 – Prevention and early detection of liver cancer
10:30 – Impact of lifestyle and diet on liver disease
12:38 – KEYNOTE-966 trial for biliary tract cancer
14:45 – Alternative strategies for liver cancer treatment
17:14 – Key initiatives of the International Liver Cancer Association
19:26 – Chan’s three wishes for healthcare
In this episode of the EMJ Podcast, Jonathan Sackier sits down with Faranak Kamangar, Chair of Dermatology at Palo Alto Medical Foundation and President of the San Francisco Dermatological Society, to discuss the future of AI and telehealth in dermatology.
Timestamps:
00:00 – Introduction
01:41 – DermGPT: bringing AI to dermatology
07:35 – Why telehealth is here to stay
11:15 – Targeted immunotherapies: what’s new?
16:57 – Using media to drive education
22:39 – Precision medicine in melanoma
27:15 – Kamangar’s podcast ‘The Future of Dermatology’
31:05 – Three wishes for healthcare
Timestamps:
00:00- Introduction
00:41- Health benefits of yoga and mindfulness
02:34- The potential of AI in hematology
04:23- Transfusion dependence in myelodysplastic syndromes
08:13- The fascinating field of apheresis
10:56- How to provide high-quality, affordable healthcare?
15:44- Regulatory T cells in hematologic malignancies
19:55- CAR T clinical trials: regulatory insights
22:57- EBMT initiatives
30:06- Latest breakthroughs in amyloidosis
34:50- Reducing patient fear through education
Supported by Gilead Sciences Europe Ltd who provided funding for this content and is intended for healthcare professionals. Gilead Sciences Europe Ltd was not involved in the creation of this content. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Gilead Sciences Europe Ltd or EMJ. Note that not all treatments discussed in this episode may have received market approval. Please refer to your local marketing authorisation and prescribing practices for guidance. The speakers received honoraria.
Tune into this episode hosted by Hannah Moir, which discusses what PBC is, and key takeaways from the AASLD conference.
In this episode of the EMJ Podcast, Jonathan Sackier speaks with Rachel Rubin, a urologist and sexual medicine specialist, about the need for patient-centred care, the importance of multidisciplinary approaches, and breaking the stigma around sexual health. Rubin also shares insights into improving medical education and advancing healthcare policies to better support sexual medicine.
Timestamps:
00:00 - Introduction
02:51 - Importance of patient-centred care in sexual medicine
06:05 - Benefits of a multidisciplinary approach to sexual health
11:45 - Gaps in sexual medicine education and training
15:20 - Addressing stigma in sexual health
23:21 - Reframing menopause in clinical practice
29:15 - Training in male and female sexual medicine
38:35 - Gender reassignment and gender-affirming care
47:45 - Three wishes for the future of sexual healthcare
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Sebastian Stintzing, Head of Department of Medicine, Division of Hematology, Oncology, and Cancer Immunology, Charité - Universitäetsmedizin Berlin, Germany. They discuss the most promising developments in gastrointestinal oncology, with particular focus on the role of personalised medicine in metastatic colorectal cancer treatment.
Timestamps:
00:00 – Introduction
03:04 – Impactful developments in gastrointestinal oncology
08:53 – Issues with funding clinical trials
14:17 – Designing trials and the importance of patient advocacy
17:11 – Translational biomarker programs
19:58 – Treatment strategies for RAS wild-type tumours
22:28 – The FIRE-4.5 study on mutant metastatic colorectal cancer
29:50 – Genetic profiling and epigenomics
33:12 – Precision medicine and immune oncology in GI cancers
34:52 – Colorectal cancer in younger adults
34:54 – Raising awareness for early screening of GI cancers
This podcast series was sponsored by Theramex UK who had no input in the content which was developed by EMJ.
The speakers were selected by Theramex and received honorarium. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Theramex or EMJ. Please refer to local marketing authorisation and prescribing practices for guidance.
Long-term Benefits of Use of MHT/HRT on the Heart, Bones, and Brain - Episode 2 - Bone expert Kassim Javaid joins Hannah Moir to explore the impact of MHT on our bones.
In this podcast series, we focus on women's health and the impact of menopause. Our experts explore the role and long-term impact of menopausal hormone therapy (MHT), otherwise referred to as hormone replacement therapy (HRT), on our heart, bones, and brain.
This podcast series was sponsored by Theramex UK who had no input in the content which was developed by EMJ.
The speakers were selected by Theramex and received honorarium. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Theramex or EMJ. Please refer to local marketing authorisation and prescribing practices for guidance.
Long-term Benefits of Use of MHT/HRT on the Heart, Bones, and Brain - Episode 1 - Heart expert Yassir Javaid joins Hannah Moir to discuss the role of MHT in cardiovascular health.
In this podcast series, we focus on women's health and the impact of menopause. Our experts explore the role and long-term impact of menopausal hormone therapy (MHT), otherwise referred to as hormone replacement therapy (HRT), on our heart, bones, and brain.
In this episode, Jonathan Sackier welcomes Andrew Blauvelt, a distinguished dermatologist and leading expert in immunodermatology. They discuss groundbreaking advancements in psoriasis treatment, including the role of high-dose biologics in achieving deep remission and how IL-23 inhibition is transforming long-term disease management.
Timestamps:
- (00:00) – Introduction
- (02:25) – A recent knockout study
- (17:22) – The wider applications of biologic treatments
- (19:40) – Deep remission in psoriasis
- (27:20) – The next frontier in psoriasis research
- (32:36) – Barriers to research breakthroughs
- (36:11) – What’s on the horizon for dermatology research?
- (41:37) – Andrew’s three wishes for healthcare
This week, Jonathan is joined by Xavier Leleu, world-renowned expert in multiple myeloma, Waldenström's macroglobulinemia, and amyloidosis. The pair discuss groundbreaking advances in clinical trials and the future of myeloma immunotherapy.
Timestamps:
(00:00)-Introduction
(00:59)-Clinical trial breakthroughs in transplant-ineligible myeloma
(03:38)-Minimal residual disease: a key endpoint
(05:21)-Rethinking therapeutic strategies in myeloma
(10:58)-Challenges in late-line myeloma therapies
(13:54)-T-cell-engaging bispecific antibodies
(17:41)-Waldenström's macroglobulinemia and amyloidosis
(21:50)-What’s next in multiple myeloma treatment?
(24:43)-Xavier’s three wishes for healthcare
In this episode, Jonathan Sackier welcomes Andrew Southerland, a distinguished neurologist and academic leader in the field of vascular neurology. They explore how machine learning is revolutionising prehospital stroke diagnosis, and how innovative strategies like telemedicine can reduce disparities in stroke care.
Timestamps:
- (00:00) – Introduction
- (03:00) – Neurologic lessons from the wild turkey
- (05:10) – Linking COVID-19 and stroke
- (10:28) – How can AI revolutionise prehospital stroke diagnosis?
- (18:39) – Stroke management in underserved populations
- (23:38) – Google Glass in medical education
- (29:06) – What is the i-corps programme?
- (33:24) – Wearable devices as diagnostic tools
- (37:08) – Andrew’s three wishes for healthcare
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Heather McArthur, Associate Professor in the Department of Medicine at University of Texas, UT Southwestern Medical Center, USA. They discuss recent advancements in breast cancer immunotherapy and the future of personalised care.
Timestamps:
00:00 - Introduction
01:20 - Transformative breakthroughs in immunotherapy
03:51 - Communicating new research to the public
05:48 - Racial disparities in cancer screenings
07:22 - Unmet needs in treating triple-negative breast cancer
11:48 - Genomic profiling and molecular pathways
13:30 - Barriers to personalised treatment plans
15:09 - Designing and conducting large-scale, international trials
19:16 - Optoacoustic imaging in cancer
22:52 - The ‘first’ cell and the heterogeneity of breast tumours
25:21 – Heather's three wishes for healthcare
This week, Jonathan sits down with Jacqueline French to explore groundbreaking innovations in epilepsy research, the challenges of misdiagnosis, and the transformative impact of advancements in clinical trial methodologies. French also shares insights into global epilepsy care challenges, and her vision for the future of neurological health.
Timestamps:
-
(00:00) - Introduction
-
(01:34) - Career beginnings
-
(07:38) - The Epilepsy Study Consortium
-
(14:48) - Ethical considerations in clinical trials
-
(17:13) - New strategies for designing trials
-
(25:25) - The evolving landscape of anti-seizure drugs
-
(27:45) - Innovative treatments
-
(32:30) - Cases of misdiagnosis
-
(35:19) - The five S’s to identify epilepsy
-
(39:12) - Educating and tackling stigma
-
(44:03) - French’s three wishes for healthcare
This week, Jonathan is joined by Eytan Stein, Chief of the Leukaemia Service and an Attending Physician at Memorial Sloan Kettering Cancer Center, New York, USA.
Timestamps:
(00:00)-Introduction
(01:05)-The current landscape of treatments
(02:26)-The promise and peril of differentiation therapy
(05:55)-Highlighting the most impactful clinical trials
(08:38)-Epigenetics and the future of targeted therapies
(10:40)-The BEAT AML master clinical trial
(12:57)-The latest research into IDH inhibitors
(16:10)-Therapies for splicing factor mutations
(19:29)-Reducing patient fear with education
(22:46)-Stein’s three wishes for healthcare
In this second part of the podcast, Jonathan welcomes back Douglas Drossman, pioneer in disorders of gut-brain interaction. He discusses key takeaways for clinicians from his ‘Gut Feelings’ book series and explores the link between trauma, drug addiction, and functional gastrointestinal disorders.
Timestamps:
-
(00:00) – Introduction
-
(0:54) – Takeaways from the ‘Gut Feelings’ series
-
(08:40) – Trauma and IBS: a complex link
-
(11:31) – Opioid-induced hyperalgesia
-
(14:18) – New horizons in the field of gut-brain interactions
-
(17:18) – Career highs and lows
-
(20:33) – AI in medical education
-
(24:01) – Drossman’s three wishes for healthcare
In this episode of the Onc Now Podcast, host Jonathan Sackier is joined by Donal Brennan, a leader in gynaecological oncology and Principal Investigator at Systems Biology Ireland. Together, they discuss advances in ovarian cancer surgery, including cytoreductive techniques and hyperthermic intraperitoneal chemotherapy (HIPEC), as well as the impact of obesity on cancer development and treatment strategies.
Brennan also shares insights on platinum resistance in ovarian cancer, the FeMMe trial exploring weight loss as a treatment for endometrial cancer, and his innovative approaches in surgical oncology.
This episode is essential listening for anyone interested in the future of cancer treatment, innovation in surgery, and patient-centred care.
Timestamps:
(00:00) - Introduction
(01:51) - Music debates in the surgical theatre
(03:42) - Evolution of surgical techniques in ovarian cancer
(06:32) - The importance of early diagnosis
(08:18) - State-of-the-art on HIPEC in gynaecological oncology
(11:36) - Obesity’s impact on cancer diagnosis and treatment
(19:06) - The FeMMe trial: weight loss as a treatment for endometrial cancer
(21:47) - Platinum resistance in ovarian cancer and future therapies
(28:14) - Innovation in gynaecological surgery and medical technology
(29:53) - The COMFORT trial: mental health and cancer treatment
(33:24) - Biggest challenges and opportunities in gynaecological oncology research
(37:42) - Three wishes for the future of cancer treatment
In this episode of the EMJ Podcast, host Jonathan Sackier welcomes William Lombardi, one of the leading innovators in chronic total occlusion (CTO) percutaneous coronary intervention (PCI). They explore his groundbreaking work in CTO technology, the development of the hybrid algorithm, and lessons interventional cardiologists can learn from aviation safety.
Lombardi also shares insights into reducing practitioner risk, the mental resilience required in high-stakes medicine, and what drives his passion for innovation.
This is a must-listen for anyone interested in advancing cardiology, operator safety, and medical innovation.
Timestamps:
(00:00) - Introduction (01:50) - The story behind ‘Lioness’ and family time on the water (06:15) - Learning from aviation: improving safety in PCI (11:14) - Changing the mindset in interventional cardiology (20:10) - The hybrid algorithm and its impact on CTO PCI (27:35) - From idea to market: innovating over 20 CTO technologies (35:14) - Reducing risk for interventional cardiologists (38:37) - The importance of mental health in performance (44:00) - Three wishes for the future of healthcare
This podcast was supported by Viatris.
The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Viatris or EMJ. Speakers have received honoraria for their participation.
Explore the challenges and solutions for managing opioid-induced constipation (OIC) in this insightful podcast, featuring discussions from a leading gastroenterologist and an expert pain specialist.
Topics covered include:
- Defining OIC prevalence, underlying mechanisms, and impact on patient wellbeing
- The risks and limitations of laxative use in managing OIC
- The role of peripherally acting mu-opioid receptor antagonists
- Strategies for improved communication and monitoring
This week, Jonathan is joined by Fredrik Schjesvold, Head of the Oslo Myeloma Center Oslo University Hospital, Head of the Norwegian myeloma association, and President of the Nordic Myeloma Study Group.
Timestamps:
(00:00)-Introduction
(04:24)-Research into melflufen
(07:14)- Ide-cel CAR T-cell therapy
(09:40)-Predictors of overall survival
(12:15)-Innovative therapies for refractory myeloma
(14:04)-Bi-specific antibodies
(16:42)-Global guidelines for myeloma
(22:00)-Healthcare economics
(25:45)-Antibody-based therapies
(29:38)- Latest research into amyloidosis
(34:23)-Recent breakthroughs in myeloma
(38:06)-Fredrik’s three wishes for healthcare
The publication of this content was funded by Beiersdorf.*
Tune into this Article Recap Join leading dermatologists and epigenetics researchers Frank Lyko, Firas Al-Niaimi, Hassan Galadari, Elke Grönniger, and Julia Gallinger in this insightful audio recap of an article exploring groundbreaking approaches to facial skin ageing. Highlights from a European Academy of Dermatology & Venereology (EADV) symposium shed light on the latest advancements in epigenetics in combination with innovative skincare interventions.
The discussion covers: * mechanisms of reversible DNA methylation changes in skin ageing and their potential for transformative treatments; * the skin-specific age clock, an AI-powered tool which measures biological skin age and supports the creation of Epicelline®, an active ingredient targeting DNA methylation to reverse clinical signs of ageing; * outcomes in laser therapies with additional use of Epicelline®; and * case studies on combining Epicelline® with aesthetic treatments such as chemical peels, microneedling, and injectables.
*The following recording is an audio article sponsored and provided by Beiersdorf, and hosted on the EMJ Podcast: Insights for Healthcare Professionals. It is aimed at healthcare professionals and recaps the symposium review article entitled, ‘Reverse the Age Clock: Reverse Clinical Signs of Ageing with Epigenetic Skin Science’, published in EMJ Dermatology 12.1 in November 2024. To access the full article, visit emjreviews.com. The content included is promotional and contains product placement, highlighting specific products or services, including paid partnerships or sponsorships. Please consult reliable resources or professional advice for any questions about the topics discussed. The opinions expressed do not necessarily represent the opinions of EMJ.
In this episode of the EMJ Podcast, host Jonathan Sackier welcomes Douglas Drossman, a pioneer in disorders of gut–brain interaction. They explore his journey from gastroenterology to psychiatry, the impact of the Rome Foundation, and how neuromodulators are transforming GI treatment.
This is part one of a two-part discussion, don’t miss part two!
Timestamps:
- (00:00) – Introduction
- (06:01) – From Rock ‘n’ Roll to Medicine: Drossman’s Musical Past
- (07:48) – The Journey from Gastroenterology to Psychiatry
- (11:35) – Breaking Barriers in Disorders of Gut–Brain Interaction
- (14:14) – The Global Impact of the Rome Foundation
- (17:34) – Neuromodulators: A Game Changer in Treating Painful Gastrointestinal Disorders
- (22:32) – Why Physician Communication Matters More Than Ever
In this episode of Onc Now, Jonathan is joined by Dr Dave Cescon, a Medical Oncologist and Clinician Scientist at the Princess Margaret Cancer Centre, Toronto, Canada. Together, they explore the transformative impact of CDK4/6 inhibitors, challenges in liquid biopsy research, and the potential of mRNA vaccines in oncology.
Timestamps:
(02:44) -Swimming in Toronto: Competitive vs. Open Water
(08:06) -From Internal Medicine to Breast Cancer Research
(14:09) -Translational research and circulating tumour DNA
(19:53) -The role of CDK4/6 inhibitors in breast cancer
(29:04) -FDA approval of ribociclib for high-risk early breast cancer
(31:45) -The future of mRNA vaccines for personalised cancer care
(37:34) -Dave’s research challenges and innovations
(39:13) -Three wishes for healthcare
This medical and educational podcast was supported by Edwards Lifesciences and is intended for healthcare professionals.
In this final episode, we learn about how Interventional Cardiologist can play a key role in improving the referral pathway of TAVI patients
Moderator
Jonathan Sackier - EMJ
Speakers: Derk Frank – Interventional Cardiologist, Professor of internal medicine, critical care, and cardiology and Director of the Department for Internal Medicine III (Cardiology, Angiology and Intensive Care Medicine,) at the University Hospital Schleswig-Holstein in Kiel, Germany and the German Centre for Cardiovascular Research Sagar Doshi – Consultant Interventional Cardiologist and Director of the Transcatheter Aortic Valve Implantation (TAVI) programme at the Queen Elizabeth Hospital Birmingham. and Professor of Cardiology Honorary Associate Clinical Professor at the University of Birmingham, and an Honorary Professor at University College Birmingham, in the UK.
In this episode, Jonathan Sackier sits down with Jane van Dis to explore the evolution of obstetrics and gynecology, the fight for gender equity in medicine, and the transformative impact of digital health and FemTech on women’s healthcare. They also discuss sustainability in medicine, and her vision for the future of equity, safety, and innovation in women’s health.
Timestamps:
(00:00)-Introduction
(01:36)-The evolution of obstetrics
(04:24)-Inequities and biases
(07:03)-Patient safety
(09:37)-Racial disparities in the USA
(11:26)-Environmental exposure
(15:50)-Equity in healthcare
(18:18)-Digital innovation in women’s health
(22:01)-Advancements in FemTech
(27:16)-Sustainability in healthcare
(32:13)-The future of women’s health
This week, Jonathan is joined by Anna Sureda, Head of the Clinical Hematology Department at Institut Català d'Oncologia - Hospital Duran i Reynals, Barcelona, Spain, and President of the European Society for Blood and Marrow Transplantation (EBMT) Association, to discuss the latest in lymphoma therapies and stem cell transplantation.
Timestamps:
(00:00)-Introduction
(01:48)-Memorable travels
(07:44)-Sureda’s journey into hematology
(12:40)-Breakthroughs in lymphoma treatment
(17:54)-Advances in stem cell transplantation
(20:26)-EBMT initiatives
(29:17)-Allogeneic transplantation for T cell lymphomas
(34:32)-Challenges in treatment accessibility
(41:35)-How can we ensure health equity?
(46:00)-Advice to young hematologists
(47:40)-Sureda’s three wishes for healthcare
This podcast has been supported by CSL Behring.
Bronchiectasis is a multifaceted condition with unique diagnostic and treatment considerations, presenting significant challenges for healthcare professionals. Join leading respiratory experts as they discuss bronchiectasis and the latest insights on managing inflammation in rare lung diseases.
Topics covered include:
- Advances in the epidemiology of bronchiectasis and its prevalence in chronic obstructive pulmonary disease and alpha 1 antitrypsin deficiency
- Recognising symptoms and identifying risk factors for recurrent exacerbations
- Diagnostic approaches, including the use of CT scans and laboratory tests
- Evidence-based treatment strategies and measures to prevent exacerbations
This week, Jonathan Sackier is joined by Janet Abrahm, Professor of Medicine at Harvard Medical School and Institute Physician at Dana-Farber Cancer Institute, to break stigmas around palliative care and explore the evolution of supportive oncology.
Timestamps:
(00:00)-Introduction
(03:55)-Abrahm’s journey into palliative care
(09:10)-A perspective on cannabinoids
(12:21)-The evolution of palliative oncology
(16:39)-Breaking stigma around palliative care
(20:20)- Differences in global approaches to palliative care
(25:43)-Medical aid in dying
(35:08)-Advice to young doctors
(37:03)-Abrahm’s three wishes for healthcare
In this episode, Jonathan Sackier sits down with David Wan to discuss the latest advances in colorectal cancer screening, the importance of high-quality colonoscopy, and the emerging role of AI in polyp detection.
Timestamps:
(00:00)-Introduction
(01:45)-Linking neuroscience and gastroenterology
(05:16)-The role of the microbiome in disease
(7:44)-Unusual clinical cases
(13:52)-Colorectal cancer screening
(21:47)-Virtual colonoscopy
(23:03)-Faecal calprotectin
(25:11)-How to ensure a high-quality colonoscopy?
(30:36)-Inpatient gastrointestinal care
(34:47)-Variceal bleeding
(36:30)-New horizons in gastroenterology
(39:53)-Wan’s three wishes for healthcare
This week, Jonathan is joined by Marc Hoffman, Associate Professor in Hematologic Malignancies and Cellular Therapeutics at the University of Kansas Medical Center, to discuss novel therapies for B-cell malignancies and current challenges in hemato-oncology.
Timestamps:
(00:00)-Introduction
(03:24)-What is molecular biophysics?
(07:01)-Marc’s journey into hemato-oncology
(09:36)-Advice to young doctors
(13:08)-Treatment advances in diffuse large B-cell lymphoma
(19:11)-BRUIN study: pirtobrutinib for B-cell malignancies
(26:15)-Challenges in CAR-T therapy implementation
(31:31)-A pharmaceutical perspective
(38:10)-Regulatory insights into clinical trials
(40:58)-New horizons in hemato-oncology
(44:26)-Marc’s three wishes for healthcare
The publication of this content was sponsored by Beiersdorf, Eucerin Tune into this Article Recap Join dermatology experts Thomas Dirschka, Alison Layton, and Marco Rocha in this engaging audio recap of the article as they explore the future of acne treatment. The article delves into how new research could reshape skincare, and assesses the current landscape for the management of acne. Discussion also covers: * the emerging role of the skin microbiome in acne development and the potential of prebiotics and probiotics to restore balance and health; * the vital importance of accurate, accessible information for young patients navigating online acne advice; and * the urgent need for patient-centred care, better communication, and increased funding to improve acne management.
Gain fresh insights into how science is reshaping the path to healthier skin, and check out the article recap now! The full article and corresponding references can be found here.
In this episode, Jonathan Sackier is joined by Eric Secemsky, a world-renowned interventional cardiologist whose innovative research and clinical expertise are redefining cardiovascular care. From pioneering advancements in pulmonary embolism interventions to leading breakthrough trials on device safety and effectiveness, Secemsky shares how cutting-edge technology and collaborative research are reshaping patient care and advancing cardiovascular treatments.
Timestamps:
(00:00)-Introduction
(02:13)-Working with athletes
(05:16)-Designing clinical trials
(10:55)-Device challenges
(15:31)-Resistant hypertension
(17:03)-Renal denervation
(23:49)-The parachute trial
(26:54)-Inaccurate autopsies
(29:49)-Limb ischaemia
(33:00)-Three wishes for healthcare
In this episode of Onc Now, Jonathan welcomes Ahmad Awada, Head of the Oncology Department at Chirec Cancer Institute in Brussels and Editor in Chief of EMJ Oncology. Together they discuss groundbreaking developments in cancer care, the promise of targeted therapies, and the importance of global collaboration in oncology.
Timestamps:
(00:00)-Introduction
(01:20)-Reflecting on ESMO 2024
(07:37)-Looking ahead to ESMO 2025
(10:04)-Pharmacokinetics and Pharmacodynamics of Antibody-Drug Conjugates
(13:24)-New cytotoxics and molecular targeted therapies for solid tumours
(16:30)-Surgery of primary tumour in de novo metastatic breast cancer
(19:29)-Improving survival in cancer patients
(22:47)-Managing the risk of thromboembolism
(24:43)-Exciting advancements on the horizon
(29:38)-Wishes for oncology
This week, Jonathan is joined by Dr Shahram Kordasti, Associate Professor in Applied Cancer Immunopathology at King’s College London, UK. In this episode, Dr Kordasti discusses the immunobiology of Myelodysplastic syndrome and Aplastic anaemia, the role of CD4+ T cells in myeloid malignancies, and how cutting-edge computational tools are enhancing treatment strategies.
Timestamps:
(00:00)-Introduction
(01:23)-Hodgkin’s lymphoma origin
(04:21)- Immunobiology of diseases
(08:55)-Plasticity of T cells
(13:42)-Computational biology and multiomics for patient stratification
(21:00)-Standardising immune monitoring
(25:41)- Pretreatment with systemic agents
(27:55)- Myeloproliferative neoplasms
(31:48)-Synthetic data generation
(36:22)-Exciting developments on the horizon
(39:16)-Three wishes for healthcare
In this episode, Jonathan Sackier sits down with Tom Bradshaw to explore the rapidly evolving landscape of digital health. They discuss Bradshaw’s expertise in the clinical application of AI and digital technologies, his work with the NHS and private sector firms, and the challenges of ensuring patient safety in an increasingly digital world.
Timestamps:
(00:00)-Introduction
(03:33)-Journey into digital health
(08:52)-AI in primary care
(12:25)-Regulating AI
(20:24)-AI guardrails
(26:31)-Human-in-the-Loop
(28:19)-AI in the NHS
(33:43)-EU regulatory standards
(37:55)-Three wishes for healthcare
As 2024 comes to a close, join EMJ Editor, Evgenia Koutsouki as she counts down the standout moments from the past year in the final instalment of our Highlights series. This special episode revisits the top six podcasts from 2024, showcasing the groundbreaking ideas, innovations, and expert insights that shaped the healthcare landscape. From exploring the genetic mysteries of parasitic infections to pioneering biosensors for gut health, this festive wrap-up celebrates a year of exceptional conversations and transformative research.
Timestamps:
(00:00)-Introduction
(00:56)-Intersection between parasitology and genetics
(05:55)-Learning from individuals with low cholesterol
(09:56)-Continuous glucose monitoring and insulin pumps
(13:43)-Brain-gut behavioural therapy
(18:47)-Biosensors to treat gut inflammatory disorders
(21:59)-Microbiome monitoring
(25:50)-Wrap up
Featured Episodes:
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The Fate of the Cell
-
Innovations in Vascular Medicine: From Bench to Bedside
-
A Personalised Approach to Diabetes
-
Gut Instincts: Bridging Psychology and Gastroenterology
-
Agar Art and Biosensor Breakthroughs
-
Microbe Monitoring: New Frontiers in Pathogen Surveillance
Evgenia Koutsouki, EMJ Editor, reflects on the most memorable moments from the EMJ Podcast over the past year in this festive highlight's episode. Throughout 2024, our podcast has featured an impressive lineup of guests discussing groundbreaking topics, including advancements in breast cancer care, the evolving landscape of heart failure treatment, revolutionary approaches to prostate disease management, and much more. Join us this holiday season as we celebrate the best conversations and insights from an incredible year in healthcare!
Timestamps:
(00:00)-Introduction
(01:00)-Advancing breast cancer care
(05:52)-The hidden drivers of hunger and weight
(12:12)-The evolving landscape of heart failure treatment
(16:24)-Revolutionising prostate disease management
(21:18)-Sepsis – the silent killer
(26:46)-Individualised prostate cancer care
(31:22)-Wrap up
Featured Episodes:
Advancing Breast Cancer Science and Patient Care
Endocrinology: The Hidden Drivers of Hunger and Weight
Heartbeats and High Achievements
Revolutionising Radiology: Innovations and Advances in the Field
The Silent Killer: Spotlight on Sepsis
Breaking Barriers in Urologic Oncology
Moderated by Sue Saville. With speakers: Susan Davis, James Simon, Tommaso Simoncini, Jean-Yves Reginster, Angelica Hirschberg. These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville. With speakers: Susan Davis, James Simon, Tommaso Simoncini, Jean-Yves Reginster, Angelica Hirschberg. These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville. With speakers: Susan Davis, James Simon, Tommaso Simoncini, Jean-Yves Reginster, Angelica Hirschberg. These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville. With speakers: Susan Davis, James Simon, Tommaso Simoncini, Jean-Yves Reginster, Angelica Hirschberg. These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville. With speakers: Susan Davis, James Simon, Tommaso Simoncini, Jean-Yves Reginster, Angelica Hirschberg. These podcasts were sponsored by Besins Healthcare.
Ed Smith, pioneer in proton beam therapy, returns to discuss AI in radiation oncology and the future of the field.
Timestamps:
(00:42) - Proton therapy in paediatric patients
(05:07) - Redlight therapy
(05:37) - Proton school
(13:00) - AI in radiation oncology
(23:57) - Future developments in radiation oncology
(26:31) - Ed’s three wishes for the radiation oncology field
In this episode, Jonathan sits down with Philip Smith to discuss groundbreaking advancements in gastroenterology, the impact of IBD research, and how his personal journey with Crohn’s disease has influenced his career. From international guidelines to the role of digital platforms in healthcare, Smith offers a compelling insight into the future of gastrointestinal medicine.
Timestamps:
(00:00)-Introduction
(02:35)-Specialising in luminal gastroenterology
(05:30)-IBD patient to practitioner
(11:20)-Career highs and lows
(17:40)-Smith’s impactful IBD research
(21:02)-The international approach to gastroenterology
(25:39)-Screening colonoscopy
(29:49)-Advancements and future priorities for IBD care
(37:37)- Leveraging social media to engage with the gastroenterology community
(43:30)-Identifying high-impact studies as EiC
(49:06)-Three wishes for healthcare
This week, Jonathan is joined by David Gómez-Almaguer, Head of the Haematology Service at University Hospital Monterrey, Mexico. They discuss advancements in stem cell transplantation, the state of haematology in Latin America, and the future of innovative therapies in the field.
Timestamps:
(00:00) – Introduction
(01:16) – David’s hobby: playing in a rock band
(03:06) – How David began in haematology
(04:35) – Stem cell transplantation and therapies
(06:27) – CAR-T cells
(07:35) – New treatments for aplastic anaemia, chronic lymphocytic leukaemia, and myelodysplastic syndrome
(10:54) – Recent clinical trial for Philadelphia positive acute lymphoblastic leukaemia
(12:55) – The current status of cord blood donation
(16:08) – Impact of race and ethnicity on outcomes after umbilical cord transplantation
(16:58) – The effect of resource and budget constraints on healthcare quality
(23:20) – Novel developments in diagnosis and treatments in haematology
(27:12) – David’s three wishes for healthcare
This podcast has been sponsored by OncoBeta, a medical device company specialising in innovative epidermal radioisotope therapies.
Don’t miss the final episode of our three-part series exploring how Rhenium skin cancer therapy (SCT) is transforming non-melanoma skin cancer treatment! Join Carmen García-Donoso and Diana Vega Pérez as they discuss their clinical experience of the novel painless, non-invasive, single-session therapy.
This episode explores:
-
What makes patients viable for Rhenium-SCT;
-
Their real-world experiences using Rhenium-SCT in practice; and
-
Potential challenges and how they could be addressed.
In this episode, Jonathan Sackier welcomes Martin Whyte to delve into the intricate world of metabolic medicine. Together, they discuss groundbreaking research on diabetes, non-alcoholic fatty liver disease, and polycystic ovarian syndrome, as well as how metabolic research is shaping the future of preventative care and treatment.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(02:10)-Journey into metabolic medicine
(03:23)-Advances in Diabetes science
(06:22)-Obesity and economic impact
(08:28)-Patient terminology discussion
(14:55)-Metabolic and chronic conditions
(19:21)-Fatty liver disease
(25:36)-Preventative health strategies
(29:51)-Future of metabolic research
(33:13)-Impact of GLP-1 drugs
(37:08)-Fertility and menstrual disorders
(41:01)-Thee wishes for healthcare
This week, Jonathan is joined by Ed Smith, Professor at the University of Manchester, UK, to discuss proton beam therapy and radiation oncology.
Timestamps:
(00:00)-Introduction
(01:43)-Ed’s favourite books and hiking spots
(05:32)-The rise of proton beam therapy (PBT)
(15:58)-PBT in the UK versus USA
(18:30)-TORPEdO: the UK's first Phase III clinical trial in PBT
This week, Jonathan welcomes Mark Connors to explore the advancements in HIV vaccine technology and the progress in global understanding of HIV since the 1980s, highlighting how these insights can inform approaches to other viruses.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(01:28)-Mark’s perfect menu
(03:23)-Choosing immunology and HIV research
(05:30)-HIV in the early 80s
(07:50)-T cell responses in controlling HIV
(13:45)- HIV history lesson
(20:50)-Merging our understanding of HIV with cancer immunotherapy
(23:12)-Challenges and breakthroughs in HIV vaccine development
(27:20)-T cell mechanisms at the sub-cellular level – the key to immunotherapies?
(29:25)-Immune responses to other viruses
(31:32)-Origin of HIV
(33:28)-Mark’s three wishes for healthcare
In this episode of Hema Now, Jonathan Sackier welcomes Christopher Patriquin, a leading expert in the field of hematology and rare diseases. With a wealth of experience in teaching, consulting, clinical research, and hosting excellent dinner parties, Patriquin’s discussion sheds light on many fascinating topics.
Timestamps:
(00:00)-Introduction
(02:00)-Dogs and dinner parties
(05:23)-Diagnosing and treating rare diseases
(09:42)-Cognitive decline in TTP survivors
(13:01)-Complement component 3 PNH therapy
(16:04)-Importance of apheresis medicine
(23:34)-The International PNH Registry
(26:52)-Developments in hematology
(28:56)-Equity and equality in access to care
(31:25)-Christopher’s three wishes
This week, Jonathan is joined by David Resühr, to discuss advances in ultrasound imaging for anatomy education, and the innovative applications of 3D printing in medicine.
Timestamps:
(00:00)-Introduction (03:33)-Early life and career beginnings (05:58)-Ultrasound imaging for anatomy education (09:07)-3D printing in medicine (14:14)-Innovations on the horizon (20:00)-Mindfulness and preventing burnout (26:47)-Ultrasound phantoms (29:10)-Becoming an author (32:34)-Cadavers versus computers (38:25)-David’s three wishes for healthcare
David Resühr’s YouTube channel can be found here: https://www.youtube.com/@anatomyinsight
Sarah Blagden, pioneer in experimental oncology, returns to the podcast to discuss cancer prediction and prevention, and the future of cancer vaccines.
Timestamps:
(00:00)- Introduction
(00:35)- The mission of RNA Guardian Ltd
(02:02)- mTOR in cancer biology
(06:24)- Raising awareness of ovarian cancer
(08:32)- A new era of cancer prediction and prevention
(11:38)- The future of cancer vaccines
(15:58)- Advice to medical students: academia versus medicine
(19:42)- Sarah’s three wishes for healthcare
This podcast was initiated and funded by Convatec. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Convatec or EMJ.
Supporting the role of nurses and multi-disciplinary teams in intermittent catheter care, providing insight into educational tools to support and improve patient wellbeing and advance the standard of care.
8 This week, Jonathan is joined by Chris McIntosh, to discuss the advancement of AI from "bench-to-bedside”, while considering concerns around bias and fairness when working with diverse patient populations.
Use the following timesamps to navigate the episode:
(00:00)-Introduction
(02:28)-An early interest in computer science
(04:13)-Clinical collaborations
(07:46)-AI from “bench to bedside”
(10:08)-Transfer and meta-learning
(12:20)-Transparency in AI
(16:32)-Commercialising radiation therapy
(18:40)-AI revolutionising oncology
(20:49)-Treating cardiovascular disease
(25:45)-Bias in AI datasets
(31:47)-The future of AI
(35:00)-Chris’ three wishes for healthcare
This week Jonathan is joined by Joshua Zeidner, Associate Professor of Medicine, University of North Carolina School of Medicine, USA. Together, they discuss findings from recent research and treatment options for acute myeloid leukaemia and myelodysplastic syndrome.
Timestamps:
(00:00)- Introduction
(01:57)- Joshua’s love for the New York Giants
(04:28)- Treatment outcomes in IDH1 and IDH2-mutated acute myeloid leukaemia (AML)
(08:05)- Safety and efficacy of new agents in AML
(17:00)- Treatments for patients with AML with a TP53 mutation
(22:02)- Reliance on transfusion in myelodysplastic syndrome (MDS)
(25:44)- The time from research lab to bedside in drugs to treat AML and MDS
(30:50)- Joshua’s three wishes for healthcare
(35:13)- Outro
This content has been funded by medac.
In this new insightful podcast, expert in oncological urology Fred Witjes, Radboud University, Nijmegen, the Netherlands, sits down to discuss management of the side effects that follow Bacillus Calmette-Guérin (BCG). Witjes dives into the absolute and relative contraindications for BCG installation, and explores some of the real-world reasons for BCG treatment discontinuation, before delving into what the signs that clinicians should look out for in their patients, and the procedures they can follow to reduce adverse events after BCG. Other topics discussed include: * Reducing the rate of lower urinary tract symptoms-related BCG treatment discontinuation; * How to increase the confidence of urologists regarding BCG side effect management; * How to make adequate use of the major drug classes used in the management of BCG side effects; and * When healthcare professionals should make the call to switch treatments.
Speakers: Fred Witjes, Radboud University, Nijmegen, the Netherlands
Are we entering a new era in the fight against antimicrobial resistance (AMR)? Listen to our latest podcast series to hear how sustainable access to effective antibiotics and diagnostic development may impact the battle against AMR.
Are we entering a new era in the fight against antimicrobial resistance (AMR)? Listen to our latest podcast series to hear how sustainable access to effective antibiotics and diagnostic development may impact the battle against AMR.
Are we entering a new era in the fight against antimicrobial resistance (AMR)? Listen to our latest podcast series to hear how sustainable access to effective antibiotics and diagnostic development may impact the battle against AMR.
- This week, Jonathan is joined by Silvia Munoz-Price, Infectious Diseases Physician; Hospital Epidemiologist; and former Chief Quality & Safety Officer, Virginia Commonwealth University Health, USA. The pair discuss lessons from the COVID-19 pandemic, vaccine hesitancy, and health equity.
Use the following timestamps to navigate this episode:
(00:09)-Introduction (02:46)-Hospital Consolidations (08:20)-Reducing safety events (10:12)-Spotting trends in quality metrics (15:10)-Vaccine hesitancy (19:44)-Preparedness ahead of COVID-19 (23:36)-How can we encourage vaccination (24:41)-The American healthcare system (31:00)-Removing politics from medicine (40:27)-Zoonoses and changing migration patterns (43:59)-Encouraging a career in epidemiology (45:07)-Silvia’s three wishes
This week, Jonathan Sackier is joined by Sarah Blagden, a pioneer of experimental oncology research, and CEO of RNA Guardian Ltd, a biotechnology company dedicated to identifying early cancer biomarkers.
Timestamps:
(00:00)-Introduction
(01:30)-Recent reads and tweets
(04:57)-Tweets and cancer acceptance
(07:36)-Sarah's journey into oncology
(09:33)-Exploring new drugs and trials
(11:48)-Global experiences and improving the clinical trial environment
(14:28)-Genetics, research, and oncology
(17:27)-Dysregulation of mRNA translation cancer
(18:36)-The future of prevention
(22:33)-Use of metformin
(26:36)-Join us for more next time!
This week, Jonathan Sackier is joined by Carlos Caldas, a world-leading expert in breast cancer research and clinician scientist at the University of Cambridge. Together, they explore how genomic-based classifications of breast cancer are transforming treatment strategies and improving patient outcomes.
Timestamps: (00:00) – Introduction
(02:00) – Carlos’s favourite cuisine
(03:32) – Carlos’s journey into oncology
(08:30) – The redefinition of breast cancer
(14:30) – How this taxonomy influences clinical care
(20:15) - Patient-derived xenografts for breast cancer
(28:00) - Circulating plasma cell-free tumour DNA as a marker of tumour burden
(33:00) – Patient derived tumour cells for drug screening
(35:00) – Vitamin B5 and environmental factors in oncology
(38:44) – Current developments in breast cancer aetiology, diagnosis or treatment
(44:00) – The three wishes for the future of healthcare
(45:00) – Outro
This week Jonathan is joined by Isabelle Amigues, CEO and Founder of UnabridgedMD, Denver, Colorado, USA. Together, they discuss the first part of her career as an academic clinician followed by how her diagnosis of Stage IV breast cancer shaped her approach to use the best in data-driven Western medicine combined with traditional Eastern healing.
Timestamps:
(00:00) - Introduction
(02:02) - Isabelle’s unique hobby: rock climbing
(03:33) - Isabelle’s journey into rheumatology
(05:58) - Being diagnosed with Stage IV breast cancer
(14:17) - The mind-body connection
(20:25) - “Hope driven by science”
(24:25) - The benefits of holistic approaches
(32:29) - Psychological distress in healthcare professionals
(37:10) - Synovial fluid and biomarker proteins
(39:48) - Isabelle’s three wishes for healthcare
(42:37) - Outro
In this episode of Hema Now, Dr. Jonathan Sackier welcomes Professor Antonio Almeida, a leader in hematology and the 2024 President of the EHA. They delve into the highlights from this year’s EHA Congress, discuss the founding of the Católica Medical School, and explore the transformative role of AI in healthcare.
Timestamps:
(00:00) -Introduction
(01:40) -Reflection on the EHA 2024 Congress
(06:10) -Approaches for future congresses
(10:30) -Proudest accomplishments and EHA education initiatives
(17:00) -Reflections on the treatment landscape of blood-related conditions
(26:00) -Importance of registries in uncovering more about these diseases
(30:10) -Potential of AI in hematology
(32:50) -Role of public policy in shaping the future of hematology
(37:00) -What drove Antonio to found a medical school
(40:00) -Antonio’s three wishes
This week, Jonathan Sackier is joined by Prof. Carlos Caldas, a world-leading expert in breast cancer research and clinician scientist at the University of Cambridge. Together, they explore how genomic-based classifications of breast cancer are transforming treatment strategies and improving patient outcomes.
Timestamps:
(00:00) – Introduction
(02:00) – Carlos’s favourite cuisine
(03:32) – Carlos’s journey into oncology
(08:30) – The redefinition of breast cancer
(14:30) – How this taxonomy influences clinical care
(20:15) - Patient-derived xenografts for breast cancer
(28:00) - Circulating plasma cell-free tumour DNA as a marker of tumour burden
(33:00) – Patient derived tumour cells for drug screening
(35:00) – Vitamin B5 and environmental factors in oncology
(38:44) – Current developments in breast cancer aetiology, diagnosis or treatment
(44:00) – The three wishes for the future of healthcare
(45:00) – Outro
In this episode, Jonathan is joined by John H. Stone, Professor of Medicine at Harvard Medical School and The Edward A. Fox Chair in Medicine at Massachusetts General Hospital. Stone discusses his groundbreaking work in systemic vasculitis, including granulomatosis with polyangiitis and ANCA-associated vasculitis. He also shares insights into the emerging field of IgG4-related disease and the exciting possibility of the first approved therapy for this condition. Alongside, he delves into his efforts to minimise glucocorticoid toxicity and his work through the IgG4ward! Foundation.
Timestamps:
(00:30) – Introduction
(04:00) – Stone’s journey into rheumatology
(07:28) – WEGET trial
(10:30) – Developments in IgG4-related disease and the path to therapy approval
(15:52) – Key advancements in the treatment of granulomatosis with polyangiitis
(18:04) – Glucocorticoid toxicity and the Glucocorticoid Toxicity Index (GTI)
(20:34) – The IgG4ward! Foundation
(23:48) – Two Pearls and a Myth
(26:45) – Stone’s three wishes for rheumatology
In this exclusive podcast, experts in the field, Andrew Foy, Penn State Health Milton S. Hershey Medical Center, and Ed Filippone, Sidney Kimmel Medical College of Thomas Jefferson University, both in Pennsylvania, USA, explore the burden of hypertension on patients and give insights into how to best care for these patients.
Topics covered include:
- patient difficulties when managing hypertension;
- blood pressure measurement and monitoring, and how to best support patients through this;
- hypertension medications and treatment resistance; and
- navigating conflicting advice and guidelines.
This week, Jonathan is joined by John ‘Jack’ Cush, Director of Clinical Rheumatology at the Baylor Research Institute, Dallas, Texas, USA. The two doctors explore novel treatment avenues for rheumatic diseases, and discuss the exciting potential of AI and telemedicine.
Please use the following timestamps to navigate this episode:
(00:00)-Introduction
(02:29)-The history of beer and rock’ n roll
(06:10)-Transitioning into digital medical education
(10:21)-Jack’s podcast: RheumNow
(14:30)-Challenges in lupus diagnosis and management
(16:58)-IL-5 inhibitors: novel drugs for allergic vasculitis
(19:22)-How does diet affect inflammation and bone health?
(24:22)-Telemedicine in rheumatology
(29:26)-Lessons in rheumatoid arthritis care
(33:30)-Soaring costs in healthcare
(36:40)-New horizons in rheumatoid arthritis treatment
(41:37)-The future of AI
(43:30)-Jack’s three wishes for rheumatology
In this bonus episode, join EMJ host Dr Hannah Moir as she speaks with our two health and wellbeing experts, Dr Sula Windgassen and Kiera McGarrity, who provide their expertise and personal experiences of using intermittent catheters. The experts address the emotional impact of intermittent catheter use and provide solutions and practical tools to support and improve patient wellbeing and advance the standard of care.
This is episode one of a three-part series: Confident Living with Intermittent Catheterisation.
This podcast was initiated and funded by Convatec. The views and opinions expressed in this podcast are those of the individual speakers and do not necessarily reflect those of Convatec or EMJ.
In this second instalment Jonathan is joined by Sunil Gupta, Consultant Haematologist and haemato-oncologist based at Lewisham and Greenwich NHS Trust, UK, to delve further into prophylactic anticoagulation in APML patients with COVID-19 and, anthracycline toxicity, and new drug appraisals for NICE.
Timestamps:
(00:00)-Introduction
(00:25)-Prophylactic anticoagulation in patients with APML
(03:26)-Anthracyclin as the cornerstone of chemotherapy
(08:18)-Developing drugs for cancer
(16:52)-New innovations in haematology
(20:00)-Sunil’s three wishes
Moderated by Sue Saville.
With speakers: Prof Dr Frank Broekmans, Prof Peter Humaidan, Prof Dr Dominic Stoop, Dr Samuel Santos-Ribeiro.
These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville.
With speakers: Prof Dr Frank Broekmans, Prof Peter Humaidan, Prof Dr Dominic Stoop, Dr Samuel Santos-Ribeiro.
These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville.
With speakers: Prof Dr Frank Broekmans, Prof Peter Humaidan, Prof Dr Dominic Stoop, Dr Samuel Santos-Ribeiro.
These podcasts were sponsored by Besins Healthcare.
Moderated by Sue Saville.
With speakers: Prof Dr Frank Broekmans, Prof Peter Humaidan, Prof Dr Dominic Stoop, Dr Samuel Santos-Ribeiro.
These podcasts were sponsored by Besins Healthcare.
This week, Jonathan is joined by Mandeep Sagoo, Professor of Ophthalmology and Ocular Oncology, UCL Institute of Ophthalmology, London, UK. The pair explore ocular oncology and Mandeep’s groundbreaking work developing a digitally engineered 3D printed ocular prosthetic.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(04:17)-Mandeep’s journey into ophthalmology
(08:06)-Pioneering work in Philadelphia, USA
(11:15)-Lessons from the US healthcare system
(13:30)-Churchill’s Fellow Award
(16:25)-Naevi and the role of ocular coherence tomography
(20:00)-How to diagnose malignancies
(30:38)-Creating prosthetic eyes following enucleation
(34:06)-3D printed prosthetics
(39:28)-Retinoblastoma
(42:45)-Innovations in molecular medicine
(44:42)-Three wishes for ocular oncology
This week, Jonathan is joined by Aniket Mohite, a distinguished member of the EMJ Oncology Editorial Board.
Timestamps:
00:00 – Introduction
01:50 – Dr Aniket Mohite’s background and bio
02:35 – Dr Mohite’s journey into haematology-oncology: challenges and rewards
06:15 – How international experience shaped Dr Mohite’s practice
13:50 – Significant research contributions and impact
17:40 – Current challenges in haematology and overcoming them
21:45 – Approaching patient education in haematology-oncology
28:50 – Discussing initiatives like World Cancer Day and supporting patients and families through cancer
31:26 – Addressing smoking and its impact on cancer treatment
36:00 – Emerging diagnostic technologies in haematology
38:50 – Dr Mohite shares his three wishes for the field of haematology-oncology
This week, Jonathan is joined by Kyle Richards, Associate Professor of Urology at the University of Wisconsin School of Medicine and Public Health, Madison, USA. The pair explore new treatment approaches for urologic cancers and the importance of patient education and comprehensive care.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(02:47)-Ice fishing is Wisconsin
(05:00)-Kyle’s passion for urologic oncology
(07:26)-Advocating for patient education
(11:25)-Agent Orange and bladder cancer
(15:59)-Screening for bladder cancer
(20:19)-The role of BCG in bladder cancer
(24:15)-Prostate cancer diagnosis
(27:12)-Penile cancer
(30:29)-Exciting advancements in the field
(33:30)-Physician led social media
(37:27)-Kyle’s three wishes for healthcare
This week Jonathan is joined by Sunil Gupta, Consultant Haematologist and haemato-oncologist based at Lewisham and Greenwich NHS Trust, UK, to discuss the effects of COVID-19 on patients with haematological conditions, and medical education globally.
Timestamps:
(00:00)-Introduction
(02:47)-Health benefits of yoga
(06:25)-Yoga, mental health, wellbeing
(08:52)-Gupta’s journey into haemato-oncology
(13:31)-Medical practices around the world
(18:55)-Impact of COVID-19 on haematology
(25:54)-Prepping for the next pandemic
(28:32)-Join us for Part 2!
Explore the importance of understanding and addressing vaccine hesitancy and consider the impact on uptake of vaccination strategies. Our discussion will consider the impact of the pandemic and the challenges and solutions associated with vaccine hesitancy in both HCPs and the public to build trust and vaccine uptake in the post-pandemic era.
The publication of this podcast series was funded by Novavax.
Explore the importance of the day-to-day practices, considering the importance of the environment and teamwork in the context of proactively preparing for vaccine distribution. Our discussion will consider implementation strategies, considering both pre and post-pandemic scenarios and the challenges and solutions associated with rapidly changing recommendations and strains.
The publication of this podcast series was funded by Novavax.
Explore the significance of understanding vaccination technologies and platforms for COVID-19 in the post-pandemic era, focusing on safety and efficacy within the vaccination landscape, with regard to the technical aspects of vaccination types and vaccine response and durability.
The publication of this podcast series was funded by Novavax.
This week, Jonathan is joined by Cristian D’Alessandro, Chief Technology Officer at RespiQ, Leiden, the Netherlands. Together, they dive into the exciting world of medical technology, and discuss D’Alessandro’s revolutionary AI-enhanced breathalyser for detecting and monitoring COPD and other diseases.
Timestamps:
(00:00)- Introduction
(02:43)- D’Alessandro’s journey into biomedical engineering
(04:12)- Differences in medical systems across the globe
(07:00)- D’Alessandro’s PhD in cardiovascular medicine and tissue engineering
(11:54)- RespiQ’s mission
(13:30)- How does RespiQ work?
(17:47)- How is RespiQ advancing the COPD treatment landscape?
(19:43)- Other diseases detectable in the breath
(22:13)- Future trends in medical technology
(24:26)- Challenges and solutions in medical innovation
(29:22) – D’Alessandro’s three wishes for healthcare
This week, Divyanshu Dua joins Jonathan for the first episode of the Onc Now podcast series, highlighting innovation in oncology. The pair discuss the future of AI in the field, as well as the importance of treatment options for older patients.
Timestamps:
(00:00)-Introduction
(02:13)-Dua’s journey into medicine
(04:33)-Cancer care for older patients
(07:37)-Advanced care planning
(10:15)-Compassionate care for all
(13:54)-Business and clinical practice
(17:45)-Skin cancer and sunscreen
(22:20)-Lung cancer today
(25:03)-Recent developments in prostate cancer
(26:57)-Dua’s global experience
(29:45)-AI in oncology
(32:15)-Three magic wishes
This week Jonathan is joined by Laren Tan, Associate Professor of Medicine, Loma Linda University Health in California, USA. Together, they address global healthcare needs, exploring innovative approaches to sustainability and equity.
Please use the following timestamps to navigate this episode:
(00:00)- Introduction
(03:36)- Laren’s unique hobby: rock tumbling
(07:12)- Laren’s journey into hyperbaric medicine
(10:24)- Navigating the healthcare conundrum in Loma Linda’s Blue Zone
(15:04)- What can the UK and USA healthcare systems learn from each other?
(23:55)- Achieving sustainability in healthcare
(27:42)- How do we rate healthcare outcomes?
(29:45)- The cost of medical education
(34:31)- The burden of documentation in healthcare
(37:43)- Laren’s experience in entrepreneurship and intrapreneurship
(40:35)- How can precision marketing transform patient care?
(43:30)- Laren’s three wishes for healthcare
This week Jonathan is joined by Ron Daniels, Founder and Executive Director of UK Sepsis Trust, and Vice President of the Global Sepsis Alliance. Together, they shatter myths and amplify awareness around sepsis, and discuss how to break barriers in diagnosis and treatment.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(03:03)-Stepping into the world of sepsis
(07:29)-Preparing for the worst in medicine
(11:10)-Dispelling common myths about sepsis
(16:02)-The overuse of antibiotics
(18:20)-The Sepsis Six treatment bundle
(21:10)-Overcoming barriers in sepsis treatment
(29:00)-Addressing resistance in education
(33:12)-Raising public awareness of sepsis
(36:43)-What can we do better?
(41:18)- Exciting developments in the world of sepsis
(43:16)-Bringing social media into play
(48:04)-Television in raising awareness
(53:10)-Ron’s three magic wishes
This week, Jonathan is joined by Neal Shore, Medical Director at Carolina Urologic Research Center and Chief Medical Officer of Surgical Oncology and Urology at GenesisCare USA. In an enlightening conversation, they discuss the latest advancements in the field of urologic oncology and the wonderment of medicine.
Timestamps:
(00:00)-Introduction
(03:08)-What initially drew Neal to urologic cancers
(05:44)-His most significant research advancements
(12:30)-The privileges of medicine
(18:45)-Changes in the field
(23:30)-Current guidance on the use of PSA to screen for prostate cancer
(28:20)-How can we drive greater awareness of men’s health issues?
(33:40)-The robotic approach to prostate cancer
(36:23)-Targeted alpha therapy
(42:10)-Exciting innovations in urologic oncology
(45:50)-Values in patient care
(50:55)-Neal’s three magic wishes
In this bonus episode of the EMJ podcast, co-hosts Eleonora De Martin, Consultant transplant hepatologist at the Centre Hépato-Biliaire, Paul Brousse Hospital in France, and patient advocate, Ingo van Thiel, from the German Liver Aid Association- Deut-sche Leber hilfe e.V., provide key insights from both the patient and clinician perspectives surrounding crucial aspects of PBC that are of importance to both patients and healthcare professionals (HCPs) alike.
They highlight the burden of PBC, its impact on a patient’s quality of life, the importance of empowering patients in their PBC care, and the collaborative effort between patients and HCPs in managing PBC, thus enabling HCPs to understand the lived experiences of patients and how it impacts their daily lives and well-being.
This podcast was organised and funded by GSK to enhance the continuing education needs and practices of healthcare professionals working with patients with Primary Biliary Cholangitis (PBC).
Listen to three experts attending EULAR 2024, who provide their recommendations on how to optimise methotrexate therapy use across various arthritis types.
Valerie Gysberts, Functional and Nutritional Medicine Therapist, Beingwell Clinic, Melbourne, Australia and Jonathan Upfal, Integrated General Practitioner, National Institute of Integrative Medicine, Melbourne, Australia, discuss their medical practice with a diverse range of patients who have often been through the medical system but have seen no improvement and have complex conditions such as chronic fatigue, ADHD, and depression.
Use the following timestamps to navigate the episode:
(00:00)-Introduction
(2:36)-From pageant queen to Functional and Nutritional Medicine Therapist
(8:10)-How the pair met
(10:50)-Working with patients with chronic fatigue, ADHD, and depression
(19:25)-Postnatal anxiety and depression
(25:05)-Zinc and copper testing
(29:50)-What can healthcare professionals do?
(32:29)-Ozempic
(36:40)-The importance of responsible use of social media
(41:15)-Jonathan and Valerie’s three wishes for healthcare
Dr. Wright shares insights into her transition to leading a major non-profit dedicated to improving the lives of those with COPD and other lung diseases. From predictive analytics to advocacy and awareness, discover how her visionary leadership is shaping the future of chronic disease management.
Timestamps:
(00:00) -Introduction
(03:16) -Jean’s journey from paediatrics and anaesthesia to becoming the CEO of the COPD Foundation
(05:56) -How Jean’s transformative approaches influenced her current role at the COPD foundation
(09:40) -Jean’s work looking at prevalence of COPD along the gorgeous Appalachians in America
(21:00) -Diagnosis rates of COPD in the US
(24:50) -If we diagnose COPD early, what can we do about it?
(27:51) -The need for investment in research
(31:00) -The vaping epidemic
(33:00) -Ways to improve our lung health
(36:30) -Reasons why women have twice the burden of COPD
(40:34) -Celebrity awareness campaign for this disease
(43:03) -Jean’s three magic wishes
Shaping the field of cardiovascular medicine, emerging technologies have the potential to transform the treatment of vascular disease. Explore the latest advancements in cardiology with Jonathan and Nicholas Leeper, Professor of Surgery, Chief of Vascular Medicine, and Director of Vascular Research at Stanford University, California, USA.
Timestamps:
(00:00)-Introduction
(02:37)-Nicholas’s journey into cardiovascular medicine
(04:40)-Exciting advancements in cardiovascular research
(07:41)-Impact of COVID-19 on clinical practice and the fear of predatory journals
(12:13)-‘Bench-to-bedside' approach
(15:50)-Bitterroot Bio and Forty Seven Inc.
(22:53)-Initiatives Nicholas is involved in that are aiding cardiovascular care
(27:22)-The future of cardiovascular medicine
(30:45)-Biological similarity between cancer and cardiovascular disease
(34:42)-Nicholas’s three magic wishes
Discover the remarkable progress made in heart failure therapies with Jonathan and Haider Warraich, Director of the Heart Failure Program at VA Boston Healthcare System, Massachusetts, USA. They also discuss the intricacies of heart transplantation and end-of-life care.
Use the following timestamps to navigate the episode:
(00:00)-Introduction
(03:28)-Warraich’s journey into cardiology
(06:15)-Recent advances in heart failure therapies
(11:15)-What is the median survival from diagnosis of heart failure?
(14:45)-The current state of heart transplantation
(20:20)-Warraich’s experience in regulatory medicine
(24:33)-Warraich’s book: ‘Modern Death, How Medicine Changed the End of Life’
(33:45)-Warraich’s s book: ‘State of the Heart’
(40:12)-Warraich’s most recent book: ‘The Song of Our Scars: The Untold Story of Pain’
(46:13)-Warraich’s three wishes for healthcare
Azra Raza, Professor of Medicine and Director of the Myelodysplastic Syndrome (MDS) Center at Columbia University in New York, joins Jonathan Sackier to discuss her mission to shift the field of oncology, ensuring it focuses on eliminating the first cancer cell rather than chasing after the last.
Timestamps:
(00:00)-Introduction
(02:37)-Poetry
(08:50)-Raza’s journey into oncology
(14:41)-Myelodysplastic syndrome and Raza’s tissue bank
(21:16)-The First Cell
(28:18)-The cancer Questions Project
(38:20)-Goals for the future
(44:40)-The most pressing issues in cancer care
(48:14)-Financially incentivising early detection
(57:00)-3 Quarks Daily
(59:10)-Three wishes for healthcare
Jonathan and Maria Eugenia Inda, Pew Postdoctoral Fellow at MIT Synthetic Biology Center in Cambridge, Massachusetts, discuss the latest developments in microbiome research and their potential applications in personalised health, as well as the fascinating world of agar art.
Timestamps:
(00:00)-Introduction
(02:57)-Agar art
(06:03)-Art influencing the scientific mind
(07:40)-Intestinal biosensors
(12:30)-Implications for healthcare professionals
(19:35)-Next steps for this technology
(23:25)-Synthetic biology
(26:23)-The importance of developing communication skills
(30:45)-Maria’s three wishes for healthcare
Jonathan Weitzman, professor of genetics at the Université Paris Cité in France, joins Jonathan Sackier to discuss the role of epigenetic events in cellular differentiation programmes, as well as his own podcast, ‘The Lonely Pipette’.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(02:49)-Specialising in epigenetics
(05:45)-Helping young scientists navigate their careers
(11:58)-Back to basics: epigenetics
(19:21)-The emergence of ‘form’
(22:02)-Cell reprogramming
(23:26)-The Centre for Epigenetics and Cell Fate
(24:28)-Genetics in 30 seconds
(29:30)-Intracellular hijackers
(35:45)-Who am I?
(41:20)-Jonathan’s three wishes
Jonathan and Vindana Chibabhai, Associate Professor in the Department of Clinical Microbiology and Infectious Diseases at the University of the Witwatersrand, Johannesburg, South Africa, discuss novel tools for pathogen surveillance, and the future of microbiology.
Timestamps:
(00:00)-Introduction
(03:20)-Podcast host to podcast host
(04:50)-Vindana’s journey into microbiology
(06:48)-Antibiotic resistance
(10:38)-Antibiotic use and food consumption
(12:31)-What can we do about antibiotic resistance?
(14:34)-Pathogen surveillance
(16:58)-HIV in sub-Saharan Africa
(20:36)-Accepting HIV treatment
(22:22)-Vindana’s current PhD work
(24:10)-Microbe Mail podcast
(26:56)-International infectious diseases
(31:31)-Preventing the spread of diseases globally
(34:45)-Future of microbiology research
(36:58)-Three wishes for the future of healthcare
Jonathan and Peter Reynolds, Consultant Neonatologist and Paediatrician based at Ashford and St. Peter's Hospital, Chertsey, UK, discuss the importance of building relationships with the families of premature babies and emerging trends and advances in neonatal care.
Please use the following timestamps to navigate the episode:
(00:00)-Introduction
(02:45)-Peter’s journey from GP to paediatrics
(05:22)-mOm incubator trial
(09:28)-The DOLFIN study
(15:01)-Feeding premature babies
(17:05)-Surfactant delivery and guideline development
(21:30)-Nasal High Flow
(26:30)-Making the delivery room ‘parent friendly’
(31:20)-IGF-1 supplements for neonates
(34:34)-Inspiration Healthcare
(40:49)-Emerging trends in neonatal care
(48:09)-Peter’s 3 wishes for healthcare
In this second instalment, Jonathan and Saira Hameed, Consultant Endocrinologist at Imperial College Healthcare NHS Trust, and a Senior Tutor and Honorary Clinical Senior Lecturer at Imperial College London, delve further into advocating for patients and collaborating across specialities. Find out her plan to prevent the children of today from ever becoming patients.
Use the following timestampsto navigate this episode!
(00:33)- Introduction
(01:03)- Dangers of drug use without a prescription
(03:17)- Perseverance in clinical research
(06:20)- Advocating for patients
(09:00)- Thinking upstream
(11:28)- Advice for aspiring medical professionals
(13:37)- Saira’s three wishes for healthcare
What is the relationship between food and metabolic health? Find out with Saira Hameed, Consultant Endocrinologist at Imperial College Healthcare NHS Trust, and a Senior Tutor and Honorary Clinical Senior Lecturer at Imperial College London. In this episode, Jonathan and Hameed discuss her book “The full Diet,” and how food intake alters energy expenditure in turn metabolic rate.
Please use the following timestamps to navigate the episode:
(00:00)-Introduction
(02:54)-The evolution of Saira’s journey
(05:49)- Imperial-SatPro weight management programme
(12:27)- The Full Diet
(20:59)- Powerful of the 200 references
(24:54)- What we eat, how we eat, and what we weigh have an impact
Is social media a force for good or evil? Find out in this week's podcast episode, where Jonathan and Brennan Spiegel, Director of Health Services Research at Cedars-Sinai Medical Center explore AI and social media, before discussing irritable bowel syndrome and the gastro-intestinal manifestations of COVID-19.
Use the following timestamps to navigate this week's episode:
(00:00)-Introduction
(01:02)- Social media as a force for good or evil
(07:36)-Artificial intelligence: preserving the humanity of healing
(11:48)-Gastro-intestinal manifestations of COVID-19
(14:34)-Navigating the assault course of the GI tract
(16:40)-Irritable bowel syndrome
(20:26)-The flaws of healthcare systems, how can technology help?
(24:55)-Brennan’s 3 wishes
Join Michelle Michels, Head of the Centre of Expertise for Inherited Cardiovascular Disease, Erasmus University Medical Centre, Rotterdam, the Netherlands, for the latest episode of the EMJ Podcast. A summary of the pathophysiology and clinical manifestations of HCM is presented, followed by a discussion on the challenges in managing HCM, the correlations between genotype and phenotype, and significant advancements derived from the analysis of long-term extension data. Listen now for more insights into this fascinating subject!
How can virtual reality improve patient care? Find out in this week's podcast episode, where Jonathan and Brennan Spiegel, Director of Health Services Research at Cedars-Sinai Medical Center discuss the philosophy of mind and the effects of virtual reality on the human mind.
Timestamps:
(00:00)-Introduction
(02:33)- Brennan’s spark towards the human body
(04:11)-The philosophy of mind
(05:08)-Effects of VR on human mind
(08:01)-VR at Cedars
(10:43)-Two sides of a coin
(13:36)-The future of augmented reality
(16:47)-The big picture of VR use
Join us for the latest EMJ Podcast episode about PBC, in which leading experts in the field discuss the newest developments and regulatory challenges in advancing treatment. David Jones, Newcastle University, UK; and Gideon Hirschfield, Toronto General Hospital, Ontario, Canada, address the impacts of treatment on patient quality of life, as well as the difficulties of collecting long-term data.
How can hypnosis be introduced in clinical practice? Find out with Sarah Partridge, Consultant in Clinical Oncology at Imperial Healthcare NHS Trust, London. In this second instalment, Jonathan and Sarah discuss success stories of hypnosis in a medical setting, and the potential benefits it provides to patient care.
Use the following timestamps to navigate the episode:
(00:00)-Introduction
(01:00)-Sarah’s approach to communicating hypnosis to patients
(06:22)-Success story of hypnosis
(08:12)-Clinical trials testing hypnosis in clinical practice
(16:30)-Sarah’s three magical wishesEpisode 204: Hypnosis: A Magical Tool in Clinical Scenarios – Part 2
Could clinical hypnosis improve outcomes for patients? Find out with Sarah Partridge, Consultant in Clinical Oncology at Imperial Healthcare NHS Trust, London. In this episode, Jonathan and Partridge discuss how hypnosis can be harnessed in a clinical setting, how it can be normalised, and its impact managing side effects.
Use the following timestamps to navigate our episode!
(00:00)-Introduction
(01:45)-Sarah’s route to clinical oncology
(04:22)-Discovering and implementing hypnosis as a tool
(08:12)-Hypnosis in managing side effects
(12:18)-Hypnosis in clinical scenarios
(16:31)-Tranceform: The era of digital resources
(21:00)-Normalising clinical hypnosis
(24:51)-Hypnosis: A different form of dissociative state
This podcast explores health psychology in gastroenterology. Jonathan and Megan Riehl, University of Michigan, Ann Arbor, USA, discuss brain-gut behavioural therapies, misconceptions surrounding mental health and gastrointestinal conditions, and her book "Mind Your Gut".
Timestamps:
(00:00)-Introduction
(03:28)-Megan’s journal to health psychology
(6:30)-Lifestyle factors and digestive distress
(10:45)-Brain-gut behavioural therapies
(17:00)-Common misconceptions in IBS
(21:34)-The microbiome: feeding your gut
(25:20)-Integrating GI mental health into practice
(29:45)- 'Mind Your Gut'
(35:06)-‘The Gut Health Podcast’
(38:40)-Megan’s three wishes for healthcare
Nick Oliver, Wynn Professor of Human Metabolism at Imperial College Healthcare NHS Trust, London, UK, joins Jonathan to discuss all things diabetes, from patient education to awareness for diabetes prevention, as well as research into islet cell transplantation.
Use the following timestamps to navigate our episode!
(00:00)-Introduction
(02:25)-Nick Oliver, playwright
(05:07)-Nick’s ‘origin story’
(07:33)-Acknowledging the current challenges in diabetes treatment, and goals for the future
(11:00)-Patient awareness and education in the treatment and management of diabetes
(15:29)-Technology in aiding diabetes treatment
(19:03)-Quality of life in real-time continuous glucose monitoring in children
(21:49)-The artificial pancreas: where is it now, and where is it going?
(26:12)-Intraocular islet cell transplantation in early-onset diabetic retinopathy
(29:54)-Innovative developments on the horizon
(33:07)-Research on increased glycaemic variability in pregnant females with gastric bypass
(35:43)-The work of the European Association for the Study of Diabetes (EASD)
(37:16)-Three wishes for the future of healthcare
This episode focuses on monogenic diabetes, diabetes research, and inspiring the next generation of nurses. Jonathan is joined by Maggie Shepherd, Honorary Clinical Professor at the University of Exeter Medical School, UK. The pair explore how we can strengthen the research influence of nurses, including the 70@70 programme, as well as Shepherd’s initiatives to encourage a career in nursing and research in nursing.
Use the following timestamps to navigate our episode!
(00:00)-Introduction (03:43)-Entering into diabetes research (04:27)-Monogenic diabetes (07:01)-70@70 initiative (11:00)-Aster Guardians Global Nursing award (12.32)-Successes, challenges, and opportunities in monogenic diabetes (14:48)-Patient care during COVID-19 (17:30)-‘1 in 6 Billion’ podcast (19:56)-Inspiring the next generation (23:09)-Maggie’s wishes for the future of healthcare
CoMiSS, the “Cow’s Milk related Symptom Score”, is a valuable resource for healthcare professionals, parents, and carers alike, offering an easy-to-use awareness tool that supports the recognition of cow’s milk-related symptoms in infants and young children.
2024 marks the 10th anniversary of CoMiSS, prompting us to look back at the decade of science and clinical practice behind the tool. The podcast reflects on the tool’s inception, its impact on aiding earlier diagnosis, and its role in evaluating therapeutic interventions for managing symptoms of cow’s milk allergy (CMA).
This podcast episode dives into the screening and management of Duchenne muscular dystrophy, as well as diversity in genetic databases, and treating neuromuscular disorders. Jonathan is joined by Madhuri Hegde, Senior Vice-President & Chief Scientific Officer at Revvity, Inc., to talk about innovation in genomic testing.
Use the following timestamps to navigate our episode!
(00:00)-Introduction
(03:54)-Entering into genomic technologies
(05:13)-Duchenne muscular dystrophy
(10:47)-Revvity and genome sequencing
(13:13)-Ultrarapid genomic testing (urWGS)
(15:18)-LANTERN project
(17:42)-Lack of diversity in genetic databases
(20:06)-New developments in genetics
(22:19)-COVID-19 testing laboratories
(27:27)-Madhuri’s wishes for healthcare
Jonathan is joined by Joshua Makower, Director and Co-Founder of the Stanford Byers Center for Biodesign, Stanford University, California, USA. The pair navigate fascinating themes, from Makower’s passion for music and his band, Still Trust, to innovative strategies for controlling rising healthcare costs through innovation. Makower offers perspectives on AI in healthcare, and the associated challenges with regulating these new technologies.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(03:05)-A passion for music
(06:11)-From the Massachusetts Institute of Technology (MIT) to medical school
(08:50)-The Biodesign process
(19:37)-Driving technology from mind to marketplace
(23:25)-Doctors engaging with industry
(27:52)-The ExploraMed incubator
(31:07)-Josh’s current work
(34:27)-The importance of failure
(36:16)-Perspectives on artificial intelligence in healthcare
(39:05)-Healthcare innovation horizons
(40:37)-Medical technology regulation
(46:00)-Josh’s three wishes for the future of healthcare
In this bonus episode of the EMJ podcast, host Sue Saville, a medical correspondent, discusses the latest advancements in access and hemostasis for coronary and other procedures via the distal radial route. Joined by Pavan Najran, clinical lead for interventional radiology and Consultant Clinical and Interventional Radiologist, The Christie Hospital NHS Foundation Trust, Manchester, UK, they further explore the benefits of the distal radial method, emphasizing reduced vascular complications, improved patient comfort, and shorter haemostasis time. Najran highlights the ergonomic advantages, dispels misconceptions, and shares insights from trials and personal experience, showcasing the potential for distal radial access to become the preferred approach.
Pavan Najran, is a clinical lead for interventional radiology and Consultant Clinical and Interventional Radiologist, The Christie Hospital NHS Foundation Trust, Manchester, UK.
The publication of this podcast was funded by Merit Medical. Dr Najran is a consultant to Merit Medicall.
The suggestions and other information, which may include both Merit and third-party products, are for the practitioner’s convenience and for general information purposes only. This information does not constitute medical or legal advice, nor is it meant to endorse or guarantee the suitability of any of the referenced products or methods for any specific patient or procedure. Before using, refer to the Instructions for Use (IFU) for indications, contraindications, warnings, precautions, and directions for use.
This podcast explores the fascinating world of artificial intelligence and advances on the horizon in oncology. Jonathan and Sofia Merajver, Michigan Medicine, Ann Arbor, USA, discuss vaccine hesitancy, the promise of artificial intelligence in generating large datasets, and non-small cell lung cancer, before concluding with her three wishes for healthcare.
Use the following tiestamps tot navigate the episode!
(00:00)-Introduction
(00:46)-Breast cancer vaccine hesitancy
(07:38)-Advances on the horizon to prevent, protect, and treat malignancies
(09:30)-Hospitals in areas of conflict
(12:20)-Artificial intelligence
(17:28)-Non-small cell lung cancer
(23:10)-Sofia’s three wishes for healthcare
This podcast explores the genetic determinants and mechanisms of breast and ovarian cancer. Jonathan and Sofia Merajver, Michigan Medicine, Ann Arbor, USA, discuss brain metastases, the severity of inflammatory breast cancer, and the movement of cancers through tissue.
Use the following timestamps to navigate this episode!
(00:00)-Introduction
(02:27)-Sofia’s journey into medicine
(04:10)-Personal stakes
(05:09)-Not being your doctor
(06:58)-Genes in inflammatory breast cancer
(10:58)-RHO proteins
(12:52)-Brain metastasis
(17:33)-Crossing the blood–brain barrier
(22:11)-Aggressive phenotypes of breast cancer
(24:18)-Chemoprevention in breast cancer
This podcast explores the mOm Incubator, the importance of collaboration with healthcare professionals when designing medical devices, and the environmental impact of healthcare. Jonathan is joined by James Roberts, co-founder and CEO of mOm Incubators Ltd., a MedTech start-up on a mission to provide global access to high-quality healthcare. The pair discuss how the mOm incubator compares to traditional incubators, and the problems it solves.
Use the following timestamps to navigate this episode!
(00:00)-Introduction
(02:11)-Sparking interest in medical innovation
(04:11)-Navigating a medical device start-up
(07:03)-Unveiling the mOm incubator
(10:19)-The value of input from HCPs in device development
(13:04)-Delivering a simple yet low-risk device
(16:14)-Supplying mOm incubators to Ukraine
(20:16)-Considering the environmental impacts of medical devices
(23:30)-James’ proudest achievements
(26:58)-Looking to the future
(28:48)-Transport for London’s map of engineering icons
(31:09)-Three wishes for the future of healthcare
In this bonus episode of the EMJ podcast, Dr. Douglas Bradley is joining our host Dr Hannah Moir to discuss the recent outcomes from the ADVENT-HF randomised clinical trial. The discussion revolves around the relationship between heart failure and co-existing obstructive and/or central sleep apnoea. Dr Bradley considers the use of adaptive servo-ventilation (ASV), a non-invasive positive airway therapy, and provides insights on the trial outcomes. He also delves into the mechanism of action underlying ASV and discusses future developments in the sleep and cardiovascular space. This podcast has been funded by Philips.
In this final episode of the series, the discussion focuses on the role of therapeutic drug monitoring and current practices, as well as how treatment decisions are made for patients refractory to anti-TNFs. The guests conclude by discussing the future of anti-TNFs and identifying the remaining gaps in the care of patients with inflammatory bowel disease.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this penultimate episode of the series on anti-TNFs for inflammatory bowel disease, our expert gastroenterologists discuss treatment options for difficult-to-treat Crohn’s disease and ulcerative colitis, including recent views and decision-making.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
Expanding the discussion of the use of anti-TNF biosimilars, in this episode, our expert panel provides insights on switching and the handling of adalimumab biosimilars.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this episode, our expert gastroenterologists consider the importance of anti-TNF biosimilars as a treatment option for inflammatory bowel disease and the corresponding guideline recommendations.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this episode, our experts discuss the use of combination therapy involving anti-TNFs and immunomodulators, with a focus on the synergy and immunogenic effects, clinical trial outcomes, and the conversations that need to be had with patients.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
Our expert gastroenterologists continue their discussion of the side effects and risks of anti-TNFs, including infection, vaccine immunogenicity, and tuberculosis (TB) risk, as well as monitoring approaches.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
Our gastroenterology experts consider the patient's underlying comorbidities when making treatment decisions regarding anti-TNFs. They also evaluate the safety profile and risks, particularly for elderly patients
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this episode, our experts discuss the recommended clinical anti-TNF treatments for inflammatory bowel disease in Europe and the USA and the patient factors that should be considered in patient decision-making.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this episode, our expert gastroenterologists provide a summary of the current ECCO and AGA recommendations for the use of anti-TNFs and insights on potential updates.
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
This introductory episode provides an introduction to the role anti-TNF therapies play in the management of inflammatory bowel disease, ulcerative colitis and Crohn’s disease
This podcast series has been supported by Viatris, who were not involved in the creation of this content.
In this week’s episode, Jonathan and George Bakris, Comprehensive Hypertension Center, University of Chicago, Illinois, USA, chat about hypertension and renal denervation.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(00:40)-Renal denervation Vs drugs in development for resistant hypertension
(06:06)-Get with the guidelines
(11:05)-Disparities in kidney disease incidence
(16:25)-Novel diabetes drugs
(19:42)-Remaining challenges in treating hypertension
(26:30)-Three wishes for healthcare
This podcast is supported by Medtronic.
This podcast episode, moderated by George Cooper, provides an exploration of the latest European Society of Hypertension (ESH) guidance on the use of renal denervation in uncontrolled hypertension management.
Atul Pathak, Princess Grace Hospital, Monaco, joins EMJ to offer key insights on renal denervation.
In this week’s episode, Jonathan and George Bakris, Comprehensive Hypertension Center, University of Chicago, Illinois, USA, discuss the role of music in medical practice, before diving into hypertension and ambulatory blood pressure monitoring.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:47)-Hoosiers and music
(08:45)-Routes into medicine
(09:47)-Finding hypertension
(13:50)-Ambulatory blood pressure monitoring
(15:10)-White coat hypertension
(16:30)-Lowering your blood pressure
(18:09)-An innocent murmur
(18:59)-Markers of kidney and heart disease
(21:10)-Two most common causes of kidney disease
(23:18)-Arterial stiffness
In this episode, Jonathan chats with Mark Little, Consultant Interventional Radiologist at the Royal Berkshire NHS Foundation Trust, Reading, UK, where he has set up a large embolotherapy research group in addition to his clinical work. The two discuss everything from their shared passion for aviation to developments in prostate artery embolisation.
Use these timestamps to navigate our episode!
(00:00)-Introduction
(02:32)-What led Little to pursue a career in radiology
(09:01)-Prostate artery embolisation
(15:02)-Genicular artery embolisation
(21:40)-Uterine artery embolisation
(24:43)-The TARGET trial: using augmented reality to guide prostate cancer biopsy
(28:05)-The role of AI in radiology
(31:50)-Innovations on the horizon for interventional radiology
(35:23)-Three wishes
In this week’s episode, Jonathan is joined by Stephanie Hanna, a Research Fellow for the Diabetes Research and Wellness Foundation, in the Division of Infection and Immunity, at Cardiff University’s School of Medicine, Wales, UK. In this fascinating episode, the pair discuss all things diabetes, including immunotherapy, the future of diagnosis, and how to predict your diabetes risk.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(01:22)-Getting into Type 1 diabetes (T1D)
(02:23)-Stages of T1D
(05:04)-Biomarkers of T1D
(07:01)-Phenotypic analysis of T and B-cells
(08:24)-Diabetes progression
(10:11)-Immunotherapy for T1D
(14:00)-Challenges in measuring immune response
(16:22)-Some thoughts on artificial intelligence
(18:11)-How to get involved in a study
(19:27)-Checking your own antibody status
(23:51)-Thyroid eye disease
(25:19)-Risks of overlooking T1D
(27:34)-Three wishes for the future of healthcare
Dr Teresa Amaral and Prof Mario Mandalà discuss: The typical patient for whom adjuvant therapy may be considered, and provide details on therapy choices. The long-term advantages of adjuvant treatments, and prospects for the use of biomarkers to help elucidate the best candidates for such therapies. The potential disadvantages of adjuvant therapy, and how more studies are needed to understand if these therapies can impact quality of life and fertility.
This content was fully funded by Novartis Pharma AG
In this bonus episode of the EMJ Podcast, host Brigitte Scott is joined by Ketta Lorusso, Humanitas University, Milan, Italy; and Rob Coleman, Vaniam Group, Chicago, Illinois, USA, who discuss key developments in endometrial cancer research that were presented in 2023.
This podcast was funded by a medical educational grant from GSK, with the purpose of enhancing the fundamental understanding of oncology specialists of key data and the latest advancements in endometrial cancer care. This content is not intended for US Healthcare Professionals.
This week’s episode focuses on innovations in diabetes technology, such as flash glucose monitoring and hybrid closed loop systems. Jonathan and Partha Kar, National Specialty Advisor in Diabetes for the National Health Service (NHS), UK, discuss promising innovations on the horizon, such as immunotherapy, as well as the importance of exercising caution on social media, and Partha’s Type 1 diabetes comic book.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:40)-Partha’s love of comic books
(04:30)-Why diabetes?
(06:09)-Promoting technology in Type 1 Diabetes
(08:25)-Patient responsibility
(10:05)-Labelling patients with diabetes
(11:28)-Hybrid closed loop systems
(14:40)-Impact on the NHS and global healthcare
(16:04)-Pioneering the diabetes ‘super six’ model
(18:02)-Social media and combatting pseudoscience
(21:15)-Considering racism
(24:06)-Diabetes on ‘the big screen’
(27:31)-Game changing drugs for diabetes
(29:40)-Innovation: stem cells and immunotherapy
(31:24)-Partha’s three wishes for healthcare
(32:40)-Concluding remarks
Jonathan is joined by Geraldine Dawson, Director of the Duke Center for Autism and Brain Development, USA. In the second of a two-part episode, the pair discuss face processing in young children with autism, the use of datasets in autism research, and biomarkers for potential treatment.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(00:42)-Digital behaviour phenotyping for the early detection of autism
(07:11)-Research on early autism detection models based on electronic health records
(12:43)-The application of artificial intelligence and computer vision in early autism detection
(15:11)-Brain circuitry, and the techniques and implications of electrophysiological techniques
(20:16)-Three wishes for the future of healthcare
In this podcast, Dr. Chryssoula Tzialla, a paediatrician and Director of the Paediatrics and Neonatalology unit at Voghera Azienda Socia-Sanitaria Territoriale of Pavia in Italy, discusses the impact of respiratory syncytial virus (RSV), the seasonal patterns of RSV, and the importance of prevention strategies, such as non-pharmacological approaches. This podcast was organised and funded by Sanofi. The statements are reflecting the opinion of the expert interviewed based on their clinical experience MAT-GLB-2306088
In this week’s episode, Jonathan is joined by Geraldine Dawson, Director of the Duke Center for Autism and Brain Development, and the Duke Autism Clinic, Durham, North Carolina, USA. In the first of a two-part episode, the pair discuss autism screening, the characteristics of autism in infancy, and the benefits of early intervention in social interactions.
Use the following timestamps to navigate the content in this episode: (00:00)-Introduction (02:15)-What led Dawson to an academic career in psychology and autism (05:09)-How do we characterise being ‘on the spectrum’? (09:29)-Aetiology of autism: genetic and environmental factors (13:20)-Dawson’s early, groundbreaking research into autism symptoms in infancy (17:17)-Why is the incidence of autism increasing? (19:45)-The Early Start Denver Model: early autism interventions (23:24)-Time Magazine’s medical breakthrough of 2012
This week, James Hull, Consultant Respiratory Physician, Royal Brompton Hospital, London, UK, takes Jonathan on a deep dive into respiratory care, from combatting breathlessness to airway collapse in athletes. The pair also discuss the common misconceptions surrounding asthma diagnosis, recent technological advancements, and the potential challenges behind emerging treatments.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(2:17)-What got Hull into medicine?
(03:34)-Relationship between exercise and breathlessness
(06:22)-Anxiety and breathlessness
(10:24)-Optimising respiratory health in elite athletes
(13:52)-RELACS; managing large airway collapse
(16:10)-New methods for diagnosing upper airway problems
(20:09)-New developments in treating asthma
(23:10)-Challenges in respiratory medicine
(25:04)-Respiratory medicine and sports committees
(26:38)-Three wishes for the future of healthcare
The information contained in this podcast is intended for a European healthcare professional audience for continuing education purposes only. This podcast was supported by Jazz Pharmaceuticals, which had input into the concept and topic, but not the content of the podcast. The views expressed in this podcast are those of the individual speakers and do not necessarily reflect the views of Jazz Pharmaceuticals.
Lennox–Gastaut syndrome (LGS) is a rare, severe, and progressive childhood-onset epilepsy characterised by recurrent seizures. LGS can be challenging to diagnose due to multiple aetiologies, varying clinical presentation at onset, and a lack of specific biological markers. These challenges can be compounded in adulthood due to the evolving presentation of LGS over time, and incomplete medical histories. In this insightful podcast, experts Steve Chung, University of Arizona, Phoenix, USA; and Rhys Thomas, Royal Victoria Infirmary, Newcastle, UK, explore the identification, diagnosis, and management of LGS in both children and adults based on their experiences in real-life clinical settings.
In this week’s episode, Jonathan is joined by Aleksander Lühr Hansen, Steno Diabetes Center, Copenhagen, Denmark; and Aarhus University Hospital, Denmark. The pair discuss low birthweight and fetal programming, in the context of the associated increased risk of developing conditions like Type 2 diabetes.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(01:50)-Alexander’s route in medicine and diabetes
(03:50)-Research on low birthweight
(05:44)-Fetal programming
(10:11)-The ‘thrifty phenotype’
(12:55)-Low birthweight and Type 2 diabetes development
(19:45)-Alexander’s experiences in Tanzania
(24.06)-Adverse pregnancy outcomes and incident heart failure
(27.19)-The translational Type 2 diabetes research group
(30:00)-Projects for the future
(33.01)-Three wishes
Jonathan is joined by Simon Fleming, orthopaedic surgeon, Royal North Shore Hospital, Sydney, Australia, and Fellow of the Royal College of Surgeons of England. Passionate about improving the quality and culture of healthcare, Simon discusses advocating for increased education standards, and his groundbreaking work to drive out bullying, discrimination, and harassment in healthcare.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:12)-Fleming the orthopod
(08:05)-Training and practicing in Britain and Australia
(13:40)-Similarities and dissimilarities
(15:56)-Rocking the boat
(21:28)-Bullying and discriminatory behaviours in healthcare
(23:11)-The BOTA census
(26:09)-TEDx NHS
(29:14)-Holding sexual predators accountable
(34:00)-Pronouns
(37:35)-#OrthoTwitter
(40:35)-Flawed assessment in healthcare
(43:46)-Influencing the next generation
(46:36)-Three wishes for the future of healthcare
The publication of this podcast was funded by CSL Behring. The views and opinions expressed are exclusively those of the speakers.
In this section, the panel considers the diagnostic tools and approaches available for healthcare professionals to use for suspected idiopathic pulmonary fibrosis (IPF). The discussion is directed towards the expertise of Prof. Luca Richeldi, who emphasises the importance of knowledge, education, and medical examination approaches for addressing the unmet medical needs associated with the awareness of, and diagnostic delays of IPF.
The publication of this podcast was funded by CSL Behring. The views and opinions expressed are exclusively those of the speakers.
In this section, which is directed towards the expertise of Prof. McElvaney, the discussion focuses specifically on the relevance of detecting and diagnosing Alpha 1 Antitrypsin Deficiency (AATD) for lung diseases, as well as consideration of other diagnostic techniques and standards of care options for patients with AATD.
The publication of this podcast was funded by CSL Behring. The views and opinions expressed are exclusively those of the speakers. In this section, the panel considers the expert insights of Prof. Wijsenbeek, concerning the challenges of predicting the disease course and prognosis of patients with idiopathic pulmonary fibrosis (IPF). The conversation reflects on current knowledge, real-world practices, treatment options, and tools available to healthcare professionals.
In this podcast episode exploring a novel radioisotope treatment for non-melanoma skin cancer, our moderator, Sue Saville, hosts two experts in skin cancer and oncological nuclear medicine.
This podcast has been sponsored by OncoBeta, a medical device company specialising in innovative epidermal radioisotope therapies.
In this week’s episode, Jonathan is joined by Jane Barratt, Secretary General of the International Federation on Ageing (IFA), an international non-governmental organisation that works with the United Nations (UN) and its agencies. The pair discuss global perceptions of ageing, approaches to elderly care around the world, and increasing inequity in service accessibility.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:11)-Jane’s passion for population aging and disability
(04:23)-Our obsession with age!
(06:56)-Considering the quality of life of elderly people
(09:20)-The importance of human companionship
(11:07)-Global and societal variations in the standard of care for the elderly
(15:20)-Aiming for a ‘kinder’ society
(16:47)-International Federation on Aging
(19:13)-COVID and vaccination denial
(24:30)- Successful care programmes in Scandinavia and China
(26:40)-Life course approach to vaccination
(28:32)-Programme and policy creation centered around the elderly
(31:43)-Petitioning healthcare professionals
(34:36)-Jane’s three wishes for healthcare
Jonathan is joined by Elizabeth Macintyre, President-Elect and Board Member of the Biomedical Alliance, Europe; and Past President of the European Haematology Association (EHA). The pair delve into the world of haematology, focusing on Macintyre’s research towards equal access, haematological diagnostics, and her presidency during the COVID-19 pandemic.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(01:39)-Macintyre’s route into medicine
(04:13)-Haematology in Europe, and leading the EHA
(08:30)-Diagnostics in haematological malignancies
(10:18)-Changes to congress following COVID-19
(14:12)-Coffee conversations
(15:36)-Madrid 2024
(18:42)-Jonathan speaks French
(24:07)-Medical politics and economics
(30:00)-Accessing new treatments
(35:43)-Three wishes for the future of healthcare
This week’s episode spotlights epilepsy, exploring research in the field, and global perspectives on this condition. Jonathan is joined by Maeike Zijlmans, who discusses the electrical activity in the brain which is causative for this disorder; seizures and loss of consciousness; and the more unknown aetiologies of epilepsy.
Maeike Zijlmans, Neurologist and Professor, University Medical Center Utrecht, and Stichting Epilepsie Instellingen Nederland, Heemstede, both in the Netherlands, shares valuable insights into her work studying both generalised and focal epilepsy, the longevity of this disease, and exciting treatment options.
Use the following timestamps to navigate the content in this episode
(00:00)-Introduction
(02:38)-Why neurology and later epilepsy research?
(03:26)-Global perspectives on epilepsy research and clinical practice
(06:30)-Aetiologies and treatment journeys associated with epilepsy
(10:29)-Raising awareness
(15:58)-Spotlighting electroencephalogram in the context of epilepsy
(18:26)-High-frequency oscillations
(21:23)-Signal analysis and phase amplitude coupling to generate an individual epileptic ‘signature’
(24:38)-Intraoperative electrocorticography in people with brain tumours
(26:40)-Surgical approaches to treating epilepsy
(29:20)-Next-generation taskforce for the International League Against Epilepsy
(31:14)-Machine learning and artificial intelligence
(34:05)-Three wishes for the future of healthcare
This week, Jonathan is joined by Michael Reardon, Houston Methodist Hospital, Texas, USA, to explore developments in treating coronary artery disease, as well as his work on various clinical trials in interventional radiology. Reardon discusses his extensive experience in performing heart surgery, focusing especially on transcatheter aortic valve implantation and transcatheter mitral valve replacements.
Follow the timestamps below!
(00.00)-Introduction
(03.09)-Michael’s inspiration for pursuing a career in cardiothoracic surgery
(04.21)-‘The TAVI Revolution’: advances in cardiac surgery
(10.15)-The Evolut Low-Risk and CoreValve trials
(11.12)-The ARISE Type A stent graft trial
(14.31)-Transcatheter mitral valve replacement: the Cephea and Apollo TMVR trials
(19.33)-Treatment of cardiac tumours
(22.33)-Cardiac tumour removal procedure
(24.51)-Structural heart disease and catheter-based treatment approaches
(26.50)-Latest advances in minimally invasive techniques in cardiac surgery
(28.52)-Risks and complications associated with complex cardiac procedures
(31.35)-Three wishes for the future of healthcare
This week’s episode explores broken heart syndrome, cardiomyocytes, and regenerative medicine. Jonathan is joined by Sian Harding, Emeritus Professor of Cardiac Pharmacology at the National Heart and Lung Institute (NHLI) at Imperial College London, UK, to discuss the relationship between emotions and heart function, as well as her research into regenerative medicine, including pluripotent stem cells, gene editing, and engineered heart tissue patches.
Use the following timestamps to navigate the content in this episode:
(00.00)-Introduction
(02.25)-What led Sian to a career in cardiology?
(03.45)-Introduction to cardiomyocytes
(05.53)-How has knowledge of cardiomyocytes changed over time?
(07.46)-Broken heart syndrome
(16.31)-Regenerative medicine in cardiology
(20.18)-Engineered heart tissue patches
(24.40)-Sian’s work in the House of Commons
(27.26)-The use of stem cells in cardiology
(29.39)-Gene editing
(32.08)-Three wishes for the future of healthcare
In this bonus episode of the EMJ Podcast, host Brigitte Scott is joined by Ketta Lorusso, Associate Professor of Obstetrics and Gynaecology, Catholic University of Rome, Italy; and Brad Monk, Professor, University of Arizona College of Medicine, USA, who discuss key research findings in endometrial cancer, as presented at the European Society for Gynecologic Oncology (ESGO) Congress 2023, which took place from 28th September–1st October 2023 in Istanbul, Türkiye.
The publication of this podcast was funded by a medical educational grant from GSK.
Jonathan is joined by António Almeida, President of the European Hematology Association (EHA); and Professor and Director of the Clinical Haematology Service, Hospital da Luz, Lisbon, Portugal, to discuss his highlights since becoming EHA President. The pair cover the three pillars of EHA, the anticipated topics for the 2024 congress, and how Almeida has implemented a brand-new medical school, as well as much more.
Use the following timestamps to navigate the content in this episode:
(00.00)-Introduction (01:55)-Almeida’s new medical school (03:35)-EHA Master Class peer-based learning and modern medical education (09:00)-Presidential highlights (11:50)-EHA’s three pillars in the coming year (16:05)-EHA 2024 in Madrid (20:15)-Research in myeloproliferative and myelodysplastic syndromes (23:00)-Clinical trial updates in myelodysplastic syndromes and chronic myeloid leukaemia (26:50)-Changes over the course of Almeida’s career (31:30)-Treatment advances on the horizon (32:50)-CRISPR to treat sickle cell disease and β-thalassaemia (36:30)-Three wishes for the future of healthcare
This episode discusses the wide range of applications of radiology, from detecting conditions that mimic cancer in pregnancy to enabling the detection of abuse in elderly patients. Refky Nicola, Associate Professor in the Department of Radiology at the State University of New York Upstate Medical University (SUNY), Syracuse, USA, joins Jonathan to discuss the Vesical Imaging Reporting and Data System (VI-RADS) in bladder cancer and the development of AI in radiology.
Use the following timestamps to navigate the topics discussed in this episode:
(00.00)-Introduction
(02.26)-What inspired Nicola to pursue a career in radiology
(04.07)-What led to Nicola migrating from emergency to abdominal radiology
(05.25)-Mimics of cancer in pregnancy
(07.13)-The Vesical Imaging Reporting and Data System in bladder cancer
(09.12)-Pitfalls of right upper quadrant ultrasound
(11.10)-Rare COVID-19 vaccine multiorgan complications
(15.40)-Role of the radiologist in detecting abuse in elderly patients
(18.35)-Use of AI in radiology
(19.54)-Three wishes
This two-part podcast series delves into vitiligo as a systemic disease, its known risk factors, and the stigma often associated with the condition. Featuring experts Amit G. Pandya, University of Texas Southwestern Medical Centre, Dallas, USA, and Thierry Passeron, Université Côte d’Azur, Nice, France, this podcast series also discusses the goals to consider in the management of patients with vitiligo, and the levels of patient satisfaction associated with current treatment options. This podcast was funded by AbbVie. The content of the podcast reflects the opinions of the speakers and does not necessarily reflect the views of AbbVie. Additional insights on living with vitiligo are available in an informative infographic, ‘The Unmet Need for Patients with Vitiligo is High’, which gives an overview of the condition’s symptoms and their impact, whilst also highlighting the comorbidities and management gaps that patients with vitiligo may experience.
This two-part podcast series delves into vitiligo as a systemic disease, its known risk factors, and the stigma often associated with the condition. Featuring experts Amit G. Pandya, University of Texas Southwestern Medical Centre, Dallas, USA, and Thierry Passeron, Université Côte d’Azur, Nice, France, this podcast series also discusses the goals to consider in the management of patients with vitiligo, and the levels of patient satisfaction associated with current treatment options. This podcast was funded by AbbVie. The content of the podcast reflects the opinions of the speakers and does not necessarily reflect the views of AbbVie. Additional insights on living with vitiligo are available in an informative infographic, ‘The Unmet Need for Patients with Vitiligo is High’, which gives an overview of the condition’s symptoms and their impact, whilst also highlighting the comorbidities and management gaps that patients with vitiligo may experience.
This week, Jonathan is joined once more by Neil Patel, Neonatologist and Clinical Innovation Director at the Royal Hospital for Children in Glasgow, UK, to explore innovations in neonatology. In this episode, Patel discusses his work in revolutionising neonatal care by embracing the use of video messaging in order to promote family involvement, and Patel’s vision to open a centre for innovation at the Royal Hospital.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(00:34)-vCreate and the challenges of introducing medical innovations
(09:30)-Opening a Centre for Innovation in Glasgow
(13:27)-Challenges in maternal and neonatal care
(17:03)-Three wishes for the future of healthcare
In this final episode, the experts consider the patient perspective of managing type 2 diabetes and its complications while tailoring treatment approaches to individual characteristics. They also consider the patient's needs with a focus towards incretin/gut hormones and providing practical insights for healthcare practice.
This podcast is provided by EMJ and was supported by independent funding from Eli Lilly and Company, who did not influence the content of it. This educational activity is intended for an audience of non-US healthcare professionals.
Prof Michael Nauck
Head of Clinical Research at the Diabetes Division Medical Department of St. Josef-Hospital, Ruhr-University in Bochum, Germany.
Professor Nauck’s research interests include the pivotal role of gastrointestinal peptide hormones, including incretins, in both the physiological and therapeutic regulation of metabolism, as well as in the pathophysiology of type 2 diabetes. His groundbreaking contributions have been significant in shaping the treatment landscape of type 2 diabetes. He has played a pivotal role in developing novel therapeutic agents based on anti-diabetic properties of the gut hormone including GLP-1 (or Glucagon-like peptide-1).
His extensive scholarly output is underscored by numerous publications, and his outstanding scientific contributions have been honoured with several awards and accolades, including the Paul Langerhans Medal (2012) bestowed by the German Diabetes Association, and the Claude Bernard Medal from the European Association for the Study of Diabetes in 2022.
Dr. Priya Manjoo
Clinical Assistant Professor in the Division of Endocrinology at the University of British Columbia in Canada.
Dr Manjoo is a diplomat of the American Board of Obesity Medicine and a Certified Specialist in Hypertension Medicine. She is also the director of the CardioMetabolic Collaborative Clinic located in Victoria, British Columbia, Canada and a member of the Victoria Lipid Clinic. She is a co-author of the Pharmacotherapy Section of the 2020 Canadian Adult Obesity Clinical Practice guidelines, as well as the 2022 chapter update and is an author of the 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia in Adults. Dr. Manjoo is a key opinion leader in the realms of diabetes, dyslipidaemia, and obesity management. Her invaluable contributions significantly contribute to advancing our understanding of these critical medical concepts.
This week, Jonathan is joined by Neil Patel, Neonatologist and Clinical Innovation Director at the Royal Hospital for Children in Glasgow, UK, to explore innovations in neonatology. Patel discusses his work on diaphragmatic hernia, a condition that requires multidisciplinary input and lifelong care. He further explains his role with the Scottish Women’s and Children’s Health Innovation Consortium, and the potential of the mOm Incubator for thermal regulation in newborns.
(00.00)-Introduction
(02.43)-Heart function through the medium of dance
(04.20)-Neil's route into paediatric medicine
(08.05)-Diaphragmatic hernia
(12.21)-Interests in innovation
(17.55)-mOm Incubators
(21.49)-Crossing the valley of doom
Antoni Chan, Consultant Rheumatologist and Associate Medical Director at the Royal Berkshire NHS Foundation Trust, Reading, UK, and Jonathan discuss digital healthcare technology and remote monitoring, and how they have impacted the field of rheumatology. Chan provides further detail, exploring how virtual multidisciplinary teams are used in the field, and touches on the digital tools and wearables that can be used to track patients with chronic conditions.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:10)-What first led Antoni into medicine
(03:14)-Antoni’s specific interests in rheumatology and ankylosing spondylitis
(05:51)-Antoni’s doctoral thesis
(07:20)-Referrals and collaboration in primary care
(09:04)-The impacts of digital healthcare technology in rheumatology
(12:11)-Specific digital tools and wearables showing promise in the management of chronic conditions
(14:05)-Using technology to improve collaboration with healthcare professionals, and communication with patients
(16:12)-The future of digital healthcare in rheumatology: trends and anticipations
(17:23)-Artificial intelligence and machine learning algorithms
(18:27)-Three wishes for the future of healthcare
In this episode, the experts focus on incretin hormones, their clinical benefits, and therapeutic approaches, providing valuable insights into incretin-based therapies, and the perspectives of the EASD-ADA guidelines and when it is clinically appropriate to start prescribing incretins for blood glucose control.
This podcast is provided by EMJ and was supported by independent funding from Eli Lilly and Company, who did not influence the content of it. This educational activity is intended for an audience of non-US healthcare professionals.
Prof Michael Nauck
Head of Clinical Research at the Diabetes Division Medical Department of St. Josef-Hospital, Ruhr-University in Bochum, Germany.
Professor Nauck’s research interests include the pivotal role of gastrointestinal peptide hormones, including incretins, in both the physiological and therapeutic regulation of metabolism, as well as in the pathophysiology of type 2 diabetes. His groundbreaking contributions have been significant in shaping the treatment landscape of type 2 diabetes. He has played a pivotal role in developing novel therapeutic agents based on anti-diabetic properties of the gut hormone including GLP-1 (or Glucagon-like peptide-1).
His extensive scholarly output is underscored by numerous publications, and his outstanding scientific contributions have been honoured with several awards and accolades, including the Paul Langerhans Medal (2012) bestowed by the German Diabetes Association, and the Claude Bernard Medal from the European Association for the Study of Diabetes in 2022.
Dr. Priya Manjoo
Clinical Assistant Professor in the Division of Endocrinology at the University of British Columbia in Canada.
Dr Manjoo is a diplomat of the American Board of Obesity Medicine and a Certified Specialist in Hypertension Medicine. She is also the director of the CardioMetabolic Collaborative Clinic located in Victoria, British Columbia, Canada and a member of the Victoria Lipid Clinic. She is a co-author of the Pharmacotherapy Section of the 2020 Canadian Adult Obesity Clinical Practice guidelines, as well as the 2022 chapter update and is an author of the 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia in Adults. Dr. Manjoo is a key opinion leader in the realms of diabetes, dyslipidaemia, and obesity management. Her invaluable contributions significantly contribute to advancing our understanding of these critical medical concepts.
Join Jonathan as he welcomes back Greg Marcus, Endowed Professor of Atrial Fibrillation, and Professor of Residence (Medicine) at the University of California, San Francisco, USA. They discuss how ethnicities need to be researched with regard to atrial fibrillation, including how adverse outcomes differ depending on an individual’s ethnicity. They also talk about digital health, and how AI devices encourage people to become more aware of their own health.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(00:37)-The economics of cardiac disease prevention and cardiac devices
(05:00)-Genetic risk across ethnic groups
(07:54)-Atrial fibrillation detected by smart watches
(12:05)-AI in cardiology
(12:49)-A new energy for common catheter ablation
(15:14)-Personalised medicine
(16:53)-Advice for young cardiologists
(20:59)-Three wishes for the future of healthcare
The publication of this podcast was funded by QIAGEN.
Tune in to our latest podcast for valuable insights on non-small cell lung cancer (NSCLC). Esteemed contributors to this discussion include Terri Conneran, a Patient Advocate and founder of KRAS Kickers, and Colin Lindsay, a Clinical Senior Lecturer and Honorary Consultant in Thoracic Medical Oncology at The Christie in Manchester, UK. Both experts underscore the pivotal importance of biomarkers, diagnostic technologies, and collaborative efforts in enhancing survivorship.
During this episode, you'll hear about the need for early biomarker testing in NSCLC, along with a forward-looking exploration of the field's future. Lindsay offers an overview of the current treatment landscape for NSCLC, shedding light on issues like late diagnosis and targeted therapies, as well as outlining next-generation sequencing and liquid biopsy as tools to enhance NSCLC testing. Patient experiences are explored, with Conneran sharing her personal journey with diagnosis and treatment.
Speaker Bios: Terri Conneran – Patient Advocate and Founder of KRAS Kickers, Charlotte, North Carolina. United States.
Colin Lindsay - Clinical Senior Lecturer and Honorary Consultant in Thoracic Medical Oncology at The Christie, Manchester
In this episode, the experts dive deeper into the mechanisms and physiological targets through which incretin hormones work (GLP-1), ensuring the harmonious balance of glucose metabolism and appetite regulation. They explore the intricate molecular pathways and unveil the physiological effects that arise from the actions of these messengers.
This podcast is provided by EMJ and was supported by independent funding from Eli Lilly and Company, who did not influence the content of it. This educational activity is intended for an audience of non-US healthcare professionals.
Prof Michael Nauck
Head of Clinical Research at the Diabetes Division Medical Department of St. Josef-Hospital, Ruhr-University in Bochum, Germany.
Professor Nauck’s research interests include the pivotal role of gastrointestinal peptide hormones, including incretins, in both the physiological and therapeutic regulation of metabolism, as well as in the pathophysiology of type 2 diabetes. His groundbreaking contributions have been significant in shaping the treatment landscape of type 2 diabetes. He has played a pivotal role in developing novel therapeutic agents based on anti-diabetic properties of the gut hormone including GLP-1 (or Glucagon-like peptide-1).
His extensive scholarly output is underscored by numerous publications, and his outstanding scientific contributions have been honoured with several awards and accolades, including the Paul Langerhans Medal (2012) bestowed by the German Diabetes Association, and the Claude Bernard Medal from the European Association for the Study of Diabetes in 2022.
Dr. Priya Manjoo
Clinical Assistant Professor in the Division of Endocrinology at the University of British Columbia in Canada.
Dr Manjoo is a diplomat of the American Board of Obesity Medicine and a Certified Specialist in Hypertension Medicine. She is also the director of the CardioMetabolic Collaborative Clinic located in Victoria, British Columbia, Canada and a member of the Victoria Lipid Clinic. She is a co-author of the Pharmacotherapy Section of the 2020 Canadian Adult Obesity Clinical Practice guidelines, as well as the 2022 chapter update and is an author of the 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia in Adults. Dr. Manjoo is a key opinion leader in the realms of diabetes, dyslipidaemia, and obesity management. Her invaluable contributions significantly contribute to advancing our understanding of these critical medical concepts.
In this final episode, Solomon Tesfaye and Oliver Binns-Hall explore the dynamic landscape of the recognition and treatment of diabetic neuropathy across diverse clinical realities in various countries. They discuss the challenges, and solutions that can help improve the management of diabetic neuropathy in different healthcare settings worldwide.
This content has been supported by Viatris
In this third episode, Solomon Tesfaye and Oliver Binns-Hall consider the transformative potential for diabetic neuropathy care. They identify the importance of integrated patient care and the need for early-stage screening and diagnosis, discussing the evolving role of the podiatrist, and the need for a well co-ordinated foot care service. They also consider innovative screening solutions and the improvements needed in the chronic management of this condition.
This content has been supported by Viatris
This week, Jonathan is joined by Greg Marcus, Endowed Professor of Atrial Fibrillation and Professor of Residence (Medicine) at the University of California, San Francisco, USA, to explore advances in the field of electrophysiology, and how substances such as coffee, alcohol, and cannabis have an effect on cardiac arrythmias, physical activity, and sleep. They further dive into the aims and results of the Health eHeart study, and how technology such as smartwatches can be used in heart disease.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(04:01)-What inspired Greg to get into medicine, and specifically into cardiology and electrophysiology
(06:30)-Electrophysiology 101
(09:10)-Coffee’s effects on cardiac arrhythmias
(15:31)-Shifts in metabolism triggered by ageing
(16:35)-The MARY-JANE Cannabis and Heart Rhythm trial
(20:09)-Effects of alcohol on heart outcomes
(26:01)-Aims and discoveries of the Health eHeart study
In this episode, Jonathan is joined by Brian Van Tine, Professor of Medicine in medical oncology and Professor of Paediatrics at the Washington University School of Medicine (WUSM) in St. Louis, Missouri, USA, to provide an overview of his clinical interest in soft tissue and bone sarcomas. The pair explore immunotherapy, specifically monoclonal antibodies and immune checkpoint blockade, and further dive into metabolomics and its relevance to oncology.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(03:50)-Brian’s inspiration for pursuing oncology
(04:43)-The rare tumour world and sarcomas
(06:13)-Immunotherapy trials
(09:21)-Treatment options for advanced alveolar soft part sarcoma
(13:52)-Genetic mutations in malignant diseases
(17:13)-Argininosuccinate synthetase 1
(22:49)-Metabolomics
(25:55)-Anthracycline-associated cardiotoxicity in patients with soft tissue sarcoma
(28:40)-Treatments available for soft tissue tumours
(31:49)-Three wishes
Tune in for a fascinating discussion with Jørgen Bjerggaard Jensen, Department of Urology, Aarhus University, Denmark, as he explores recent breakthroughs in non-muscle-invasive bladder cancer (NMIBC) management through mitomycin C (MMC) chemoresection. Jensen addresses the critical need to advance NMIBC management, underscoring its unique status as a disease of field cancerisation. Delving into the study’s main findings, Jensen discusses the efficacy of MMC chemoresection and the potential effectiveness in both low-grade and high-grade Ta tumours. Safety and tolerability aspects are also examined, highlighting the promise this intervention holds for patients and urologists alike. This content was funded by medac GmbH.
Two experts in medical oncology explore the latest developments in metastatic colorectal cancer in this episode of the EMJ podcast. Elena Élez, Vall d’Hebron University Hospital and Vall d’Hebron Institute of Oncology, Barcelona, Spain; and Michel Ducreux, Gustave Roussy, Villejuif, France, and Paris-Saclay University, France, discuss current treatment guidelines for patients with mCRC BRAF V600E mutation.
This podcast has been funded by Pierre Fabre; the position and discussions might not represent the position of Pierre Fabre.
Michelle Kelly-Irving, Director of Research at the Center for Epidemiology and Population Health Research, Faculty of Medicine, Paul Sabatier University, Toulouse, France, joins Jonathan to discuss social, economic, minority, and gender inequalities across healthcare systems and the life-course; her epidemiological research projects; and the concept of the exposome, highlighting how environmental exposures impact biology and human health.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:12)-A diverse upbringing and disciplinary mix
(04:20)-Social determinants of biology
(06:12)- The exposome
(09:26)-Falling down the rabbit hole
(11:47)-Gender and health inequalities
(15:00)-Man flu!
(19:52)-Social deprivation and COVID
(25:35)-Health trajectories and influencing people earlier in life
(28:16)-Three wishes
In this second podcast, Kevin Boehnke and Dan Clauw consider the experiences of the healthcare professional when it comes to treating fibromyalgia. They emphasise the significance of shared decision-making between both the patient and practitioner. They also explore the available treatment options, and consider the role of non-pharmacological approaches in managing this condition.
Speakers Dr Kevin Boehnke
Research Assistant Professor, Department of Anaesthesiology and the Chronic Pain and Fatigue Research Centre, University of Michigan Medical School, Ann Arbor, USA
Dr Boehnke received his doctorate from the University of Michigan School of Public Health in Environmental Health Sciences in 2017. Dr Boehnke’s current research focuses on therapeutic applications of cannabis and psychedelics where his goal is to rigorously assess appropriate use of these substances and to help address the public health harms caused by their criminalisation. He is also a yoga instructor and he himself lives with fibromyalgia.
Professor Daniel Clauw
Professor of Anasthesiology, Internal Medicine of Rheumatology and Psychiatry, and the Chronic Pain and Fatigue Research Centre, University of Michigan Medical School, Ann Arbor, USA
Professor Clauw serves as Director of the Chronic Pain and Fatigue Research Centre at the University of Michigan, USA and co-directs the Research Development Core and Pre-Doctoral Programs. His research is committed to clinical care and research into the central nervous system. He is an international expert in chronic pain disorders, such as fibromyalgia, where he incorporates a multitude of methods ranging from patient-reported outcomes to functional and chemical neuroimaging, and phenotyping, and as such, has been critical in helping elucidate the importance of the central nervous system in chronic pain conditions.
This content has been supported by Viatris
In this episode, the experts provide an understanding of the intricate role gut hormones play in glucose and appetite regulation. Also, to shed light on the vital role played by these nutrient-stimulated hormones, and their profound influence on energy, glucose regulation and their intricate interactions with target tissues.
This podcast is provided by EMJ and was supported by independent funding from Eli Lilly and Company, who did not influence the content of it. This educational activity is intended for an audience of non-US healthcare professionals.
Byungyol ‘Bill’ Chun, Owner of Women’s Healthcare of Woburn, Massachusetts, USA, Founder of Women Only Organics (WOO), and Co-founder of Doc & Doula, joins Jonathan to discuss the menopause, abortion, and the profit-based healthcare system in the USA.
You can find more information about doulas, which are discussed during this podcast, on the Doulas for Everyone website.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:50)-Born to be an OBGYN
(05:00)-Training in Boston City Hospital
(06:00)-Caesarean-section and induction of labour in 2023
(07:30)-Shortage of OBGYNs
(09:00)-State of women’s health
(11:25)-Positive patient and doctor interaction
(15:30)-Inside information on women’s healthcare
(17:20)-The taboo on menopause
(21:20)-Six reasons why women’s healthcare is a disaster
(25:20)-CBD in women’s healthcare
(30:39)-Access to abortion
(36:25)-Doc & Doula to empower women
(41:20)-Ask Bill
(42:30)-Three wishes
Featuring leading cardiology experts, this podcast episode navigates atherosclerotic cardiovascular disease (ASCVD), including plaque morphology, residual risk, secondary treatment options, and guidelines from the National Institute for Health and Care Excellence (NICE). They also detail how these different treatment options work, and conclude the episode by sharing relevant patient case studies that reflect the themes discussed. Lale Tokgözoğlu, Professor of Cardiology, Hacettepe University, Ankara, Turkey; and Pierre Sabouret, Heart Institute, ACTION Study Group-CHU Pitié-Salpêtrière University Hospital, Paris, France, join EMJ to share their expert insights on this pertinent topic. Following the recording of this podcast the European Society of Cardiology (ESC) 2023 Guidelines have been updated. Please refer to your local guidelines and relevant prescribing information for the most up-to-date information. Disclaimer: This podcast is sponsored by an educational grant by Amarin. The speakers opinion is entirely their own and did not receive an honorarium for their part.
This week, Jennifer Dixon joins Jonathan to share the mission of The Health Foundation, which she is Chief Executive Office of. The pair discuss the resource allocation formula that was created, taking into account the needs of the population, as well as the future of national strategy in health and healthcare. They further explore underfunding in the National Health Service (NHS), and the importance of investing in community care.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:05)-Dixon’s route into medicine
(03:57)-The Health Foundation
(08:00)-Future strategies for national healthcare systems
(14:05)-’The thermostat is set too cold’, Europe versus the USA
(18:32)-Dixon’s publications
(24:40)-Telehealth and artificial intelligence as tools in healthcare
(26:50)-’Money is too tight to mention’ and the NHS as a ‘political hot potato’
(32:24)-The highs and lows with global healthcare provision
(24:40)-Future services
(37:46)-Use of social media and Dixon’s ‘a-ha!’ moments
(42:08)-Dixon’s three wishes
Discussing the burden of hypertrophic cardiomyopathy (HCM), expert in this field Pablo Garcia-Pavia, Puerta de Hierro Majadahonda University Hospital, Madrid, Spain, sheds light on the diagnosis and treatment of HCM. Further discussion centres around myosin inhibitor drugs, specifically their mechanism of action, associated advantages and limitations, and their relevance to HCM subtypes are outlined. Relevant studies presented at the European Society of Cardiology (ESC) Congress 2023, as well as ongoing clinical trials and research initiatives focused on myosin inhibitors and HCM treatment, are also summarised. It'll also highlight the latest ESC Guidelines and how they play a crucial role in shaping clinical practice, before looking ahead to the most promising advancements in the field of HCM treatment. This medical education podcast was sponsored by Myokardia and Bristol Myers Squibb.
In this episode, Jonathan is once again joined by Vikram Talaulikar, Associate Specialist in reproductive medicine at the University College London Hospitals (UCLH) NHS Foundation Trust, UK, to explore different treatment options for menopause, including lifestyle changes, alternative medicine, hormone replacement therapy, and non-hormonal treatments. They further dive into the symptoms, diagnosis, and treatment of polycystic ovary syndrome, and implications of oestrogen deficiency.
Use the following timestamps to navigate the topics in this episode:
(00:00)-Introduction
(00:43)-Treatments for menopause: benefits and side effects
(11:30)-Reasons for, and impact of, perimenopause
(16:18)-Polycystic ovary syndrome 101
(22:29)-Oestrogen deficiency and its implications
(25:53)-Three wishes for the future of healthcare
In the first episode, Solomon Tesfaye and Ollie Binns-Hall explore the pressing issue of the diabetes epidemic and its most prevalent microvascular complication: neuropathy. They discuss the identification and characterisation of these critical aspects of diabetes and explore the causes, symptoms, and challenges of diagnosing neuropathy within the broader context of diabetes.
This content has been supported by Viatris
In the second episode, Solomon Tesfaye and Ollie Binns-Hall unravel the intricate relationship between diabetes and pain. They focus on the current approaches to identifying diabetic peripheral neuropathy and explore the risk factors, and current detection and management approaches, identifying the challenges associated with managing this multifaceted condition.
This content has been supported by Viatris
This podcast, featuring Dr. João Neves, a pediatrician and Associate Professor at Nova Medical School in Lisbon, Portugal, who has a Ph.D. in immunology, also Head of the Paediatrics Department at the Hospital da Luz in Lisbon, will delve into the intricacies of RSV, exploring its structure, transmission, symptoms, its impact on both healthy and at-risk infants, the epidemiology surrounding it, its seasonality, and its relationship with the ongoing COVID pandemic.
This podcast was organized and funded by Sanofi. The statements are reflecting the opinion of the expert interviewed based on his clinical experience
MAT-GLB-2301791
Vikram Talaulikar, Associate Specialist in reproductive medicine at the University College London Hospitals (UCLH) NHS Foundation Trust, UK, joins Jonathan to discuss menopause symptoms, how these can differ depending on ethnicity, how they vary over time, and possible treatments.
Use the following timestamps to navigate the topics in this episode:
(00:00)-Introduction
(02:38)-Vikram’s inspiration in pursuing his career
(04:00)-Explaining perimenopause and menopause
(08:21)-Ethnic differences in experience of menopause, and areas where further research is needed
(13:22)-Post-menopause: the most productive years of a woman’s life?
(20:15)-What GPs and specialists need to understand about the field
In this first podcast, Kevin Boehnke and Dan Clauw delve into the patient’s perspective regarding the burden of fibromyalgia. They explore the impact of fibromyalgia on a person’s life, with Kevin sharing his personal experiences. Both experts also evaluate the significance of non-pharmaceutical treatment options for managing this condition.
Speakers Dr Kevin Boehnke
Research Assistant Professor, Department of Anaesthesiology and the Chronic Pain and Fatigue Research Centre, University of Michigan Medical School, Ann Arbor, USA
Dr Boehnke received his doctorate from the University of Michigan School of Public Health in Environmental Health Sciences in 2017. Dr Boehnke’s current research focuses on therapeutic applications of cannabis and psychedelics where his goal is to rigorously assess appropriate use of these substances and to help address the public health harms caused by their criminalisation. He is also a yoga instructor and he himself lives with fibromyalgia.
Professor Daniel Clauw
Professor of Anasthesiology, Internal Medicine of Rheumatology and Psychiatry, and the Chronic Pain and Fatigue Research Centre, University of Michigan Medical School, Ann Arbor, USA
Professor Clauw serves as Director of the Chronic Pain and Fatigue Research Centre at the University of Michigan, USA and co-directs the Research Development Core and Pre-Doctoral Programs. His research is committed to clinical care and research into the central nervous system. He is an international expert in chronic pain disorders, such as fibromyalgia, where he incorporates a multitude of methods ranging from patient-reported outcomes to functional and chemical neuroimaging, and phenotyping, and as such, has been critical in helping elucidate the importance of the central nervous system in chronic pain conditions.
This content has been supported by Viatris
In the second part of this podcast, Jonathan and Mark de Boer, current president of the Dutch Working Party on Antibiotic Policy (SWAB) focus on the ‘marathon’ of antimicrobial resistance and common misconceptions surrounding this topic . De Boer then outlines the future of infectious disease management, highlighting the crucial role of healthcare professionals, policy makers, and the general public in combatting the ‘slow pandemic’.
Use the following timestamps to navigate the topics in this episode:
(00:00)-Introduction (00:42)-Antimicrobial stewardship to combat the rise of resistant infections (05:06)-Main findings from de Boer’s study on antibiotic prescriptions in primary care (08:57)-Research in evolving epidemiology of antimicrobial resistance (11:29)-Common misconceptions made by healthcare professionals and the public (13:40)-The ‘marathon’ of antimicrobial resistance and perceptions of antibiotics (15:53)-Future of infectious disease management and antibiotic policy (19:41)-Three wishes for global healthcare
Article 'Trends in antibiotic selection pressure generated in primary care and their association with sentinel antimicrobial resistance patterns in Europe': https://academic.oup.com/jac/article/78/5/1245/7099685
Article 'The Dutch Working Party on Antibiotic Policy (SWAB) guideline for the approach to suspected antibiotic allergy': https://www.sciencedirect.com/science/article/pii/S1198743X23001787?via%3Dihubhttps://pubmed.ncbi.nlm.nih.gov/37068548/
Survey discussed: https://academic.oup.com/cid/search-results?page=1&q=westgeest&fl_SiteID=5269&SearchSourceType=1&allJournals=1#google_vignette
This week, Jonathan is joined by Mark de Boer, Professor of Infectious Diseases at Leiden University Medical Center (LUMC), the Netherlands, and the current president of the Dutch Working Party on Antibiotic Policy (SWAB). The pair explore the global scale of the “slow pandemic” of antimicrobial resistance, the learning curve of the COVID-19 pandemic, and how we can prepare for future infectious disease management. They also discuss disinformation, the importance of collaboration, and implications for patient care following prosthetic joint infection.
Use the following timestamps to navigate the topics in this episode:
(00:00)-Introduction
(02:27)-Why medicine and infectious diseases
(05:18)-The scale of antibiotic resistance
(09:52)-Antibiotics use in the food industry
(11:30)-International collaborations
(15:00)-Lessons learnt from hospitalised COVID-19 patients
(20:10)-Future infectious disease management and policy
(22:47)-Prosthetic joint infection
Prof. Torsten Witte, Director of the Dept. of Rheumatology and Clinical Immunology at the Hannover Medical School in Germany, Prof. Andrea Rubbert-Roth, Chief physician and deputy clinic head at the Clinic of Rheumatology, Canton Hospital, St. Gallen, Switzerland and Dr. Alessandro Giollo, lead of refractory arthritis, synovial biopsy and osteoporosis clinics at the Rheumatology Unit, Department of Medicine, University of Padova, in Italy delve into the latest advancements and offer perspectives in the management of rheumatoid arthritis with a specific focus on optimising methotrexate.
This podcast has been funded by Medac Gm-bh.
Evgenia Koutsouki, EMJ Editor, pulls together her favourite moments from the last quarter of the EMJ Podcast. Over the summer, our podcast welcomed an array of great guests, who discussed a multitude of topics, including the links between climate change and mental health, robotic surgery, and disparities in healthcare.
Use the following timestamps to navigate this episode:
(00:00)-Introduction
(00:35)-Richard Cohen discusses the benefits of robotic surgery
(01:37)-Arthur Burnett stresses the importance of the HPV vaccine in urology
(03:02)-Arthur Burnett on the impacts that healthcare disparities have upon survival rates
(03:29)-Samuel Washington speaks about financial barriers impacting outcomes for patients
(04:20)-Christine Ko talks about factors affecting the commonality of skin cancers
(05:16)-Christine Ko goes on to talk about visual perception in dermatology
(06:13)-Eva Parker emphasises the intersectionality between dermatological diseases, mental health, and climate change
(07:42)-Michela Starace questions the quality of life and mental health for patients with alopecia areata
(09:00)-Michela Starace discusses JAK inhibitors in the treatment of alopecia
(10:33)-Morag Griffin provides details on the rare condition paroxysmal nocturnal haemoglobinuria
(11:51)-Morag Griffin stresses the importance of international collaboration in rare diseases
(13:00)-Mark Sullivan highlights the difficulties of finding funding, and how this affects drug development
(14:12)-Mark Sullivan talks about access to healthcare as a fundamental human right
Exploring the most important developments in the field of endometrial cancer, this podcast episode features two highly esteemed guests: Bradley Monk, University of Arizona College of Medicine – Tucson, USA, and Creighton University School of Medicine, Omaha, Nebraska, USA; and Robert Coleman, Chief Medical Officer, Vaniam Group, Chicago, Illinois, USA. The experts offer their perspectives on recent information presented at the Society of Gynecologic Oncology (SGO) and American Society of Clinical Oncology (ASCO) annual meetings. Discussing the most common gynaecological malignancy in developed countries, this episode investigates the challenges associated with disease diagnosis, staging, stratification, and treatment. The discussions in this podcast cover the complexities of endometrial cancer, standard of care biomarkers, and efforts to personalise treatment. The experts also deliver an update on the important ongoing clinical trials that created a real buzz at both congresses. This podcast was funded by a medical educational grant from GSK, with the purpose of enhancing the fundamental understanding of oncology specialists of key data and the latest advancements in endometrial cancer care.
Silke Gillessen, Director of the Oncology Institute of Southern Switzerland, Bellinzona, Switzerland, joins Jonathan to discuss her specialty of genitourinary oncology, and why personalised and precise treatment is so vital.
Listen to the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(03:10)-Gillessen’s origin story
(04:25)-Differences and similarities in access to care between countries
(06:26)-Inspiration to start the medical oncology unit for genitourinary cancer Kantonsspital St. Gallen
(08:16)-Gillessen’s experience in the UK
(11:00)-How evidence-based medicine can best influence adoption of ESMO guidelines
(14:18)-The meaning of precision oncology and novel treatments for prostate, testicular, and penile cancers
(17:17)-How ESMO can help support patients dealing with a cancer diagnosis
(20:47)-Treatment for patients with castration-resistant prostate cancer
(23:52)-Optimising treatment for metastatic prostate cancer
(25:51)-Molecular targeted drugs and immunotherapy in prostate cancer
(27:40)-Three wishes
This week, Jonathan is joined by Sophie Lanzkron, Professor of Medicine in the Division of Hematology at the Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. The pair explores sickle cell disease and advancements in its treatment, including hydroxyurea and blood transfusions, as well as advancements in haplotype transplant and gene therapy. They further discuss challenges in diagnosis and treatment, and how the condition affects quality of life.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02:33)-Inspiration to work in haematology and sickle cell disease
(05:00)-Sickle cell disease: what is it and how does it affect quality of life
(08:30)-Efficiency and use of hydroxyurea
(13:00)-Infusion clinic outcomes versus emergency department outcomes
(16:08)-Treating patients with sickle cell disease by blood transfusions
(17:40)-Global prevalence and burden of sickle cell disease
(20:20)-Challenges faced by patients during diagnosis and treatment
(23:53)-Novel sickle cell disease healthcare delivery model
(26:27)-Perfecting treatment for sickle cell disease
(29:15)-Research focus in the future
(31:22)-Lanzkron’s three wishes for the future
This week, Jonathan is joined by Drew Bird, Director of the Food Allergy Center at Children’s Health, Dallas, Texas, USA, to dive into environmental factors that have led to the increase in allergies, including peanut allergy, and oral immunotherapy as a treatment for allergies. The pair further discuss misconceptions and misinformation around allergies, and which allergies need more attention.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:28)-Bird’s career in paediatric allergy and immunology
(04:50)-Misconceptions in the field
(08:47)-Using food proteins for immunotherapy
(11:53)-Bird’s role as Director of the Food Allergy Center at Children’s Health
(16:46)-Unmet needs in paediatric food allergies
(18:05)-The PALISADE Study
(19:39)-Food protein-induced enterocolitis syndrome
(21:46)-Environmental factors and emerging allergies
(26:36)-Innovations in the allergy and immunology field
(30:51)-Advocating for young patients to promote effective healthcare
(33:15)-Bird’s three wishes for the future of healthcare
Mark Sullivan, Medicines for Global Health (MDGH), Melbourne, Australia, joins Jonathan to discuss global health inequality, the difficulties in finding funding as a Managing Director of a not-for-profit pharmaceutical company, and infectious diseases such as Hanson’s disease and river blindness.
Use the following timestamps to navigate the podcast topics:
(00:00)-Introduction
(01:55)-What led Sullivan into biochemistry and microbiology
(03:04)-Sullivan’s subsequent career in Pharma
(04:36)-The world’s only non-profit biopharmaceutical company
(7:28)-Approval of moxidectin
(14:15)-Hansen’s Disease: causes, host response, and treatment
(19:04)-Innovative medicines to treat the diseases of low- and middle-income countries
(22:20)-How to tackle the enormous expenditure in low- and middle-income countries
(30:56)-Product development partnerships
(34:37)-How healthcare professionals can help
(37:25)-Three wishes to improve global healthcare
Speaker: Prof. Dominic Stoop
Topic: “Did you know!” The cycle-to-cycle variability can be influenced by Progesterone
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Dominic Stoop
Topic: “Did you know!” The lower limit of Progesterone that needs supplementation?
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Nikolaos Polyzos.
Topic: “Did you know!” You can also plan natural cycles with the use of Progesterone – NPP?
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Nikolaos Polyzos.
Topic: “Did you know!” That you can stimulate at any time of the cycle, even in the luteal phase
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Peter Humaidan.
Topic: “Did you know!” The optimal cut-off level of serum progesterone in the adenomyosis/endrometriosis patient is for times higher than that in a “normal patient”
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Petra Stute.
Topic: “Did you know!” Many menopausal women suffer from brain fog.
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Petra Stute.
Topic: “Did you know!” Taking oral estradiol has increased risk of venous thromboembolism but not with transdermal estradiol
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Andrea Genazzani.
Topic: “Did you know!” You can continue hormane therapy as long as the patient is symptomatic?
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Andrea Genazzani.
Topic: “Did you know!” Body-identical hormones like estradiol and micronized progesterone are approved, regulated and monitored for purity, efficacy and safety by regulatory agencies unlike compounded bio-identical hormones prepared by compounding pharmacists
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Tommaso Simoncini.
Topic: “Did you know!” It is possible to start menopause hormone therapy if you have symptoms and indications for that, even at later stages?
This podcast was sponsored by Besin Healthcare
Speaker: Prof. Tommaso Simoncini.
Topic: “Did you know!” Hormone therapy remains the most effective treatment for vasomotor symptoms and the genitourinary syndrome of menopause?
This podcast was sponsored by Besin Healthcare
This week, Jonathan is joined by Kevin Tracey, Feinstein Institutes for Medical Research, Manhasset, New York, USA, to explore bioelectronic medicine; its use in the treatment of inflammation, including rheumatoid arthritis; and its future. The pair further dives into the vagus nerve and the link between vagotomy and Parkinson’s disease, and the use of monoclonal anti-TNF antibodies to treat septic shock.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(02.36)-Tracey’s origin story and route into medicine
(04.46)-Defining bioelectronic medicine
(07.15)-Septic shock and monoclonal anti-TNF antibodies
(10:10)-The vagus nerve and 1493
(22:15)-Vagotomy and Parkinson’s disease
(26:32)-Optogenetics
(29:52)-Replacing pharmaceuticals with bioelectronics
(32:59)-Saving lives with vagus nerve stimulation to treat inflammation
(35:01)-Cancer neuroscience
(36:52)-Tracey’s three wishes for improving his field of specialty
Michela Starace, Department of Medical and Surgical Sciences, University of Bologna, Italy, joins Jonathan to discuss hair loss and its impact on the lives of patients. They also explore how symptoms of conditions can present in nails, and how to treat benign nail tumours.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:53)-What led Starace into medicine, and the field of dermatology
(03:20)-Alopecia areata, the role of JAK inhibitors, and adverse treatment events
(06:40)-Commonality of alopecia areata, and its recent reclassification as an autoimmune disease
(07:35)-Health-related quality of life and psychosocial anxiety in patients with hair loss
(10:03)-Recommendations for the treatment of female androgenetic alopecia
(12:03)-The role of trichoscopy in diagnostics
(14:36)-Onychoscopy in the diagnosis of nail disorders
(17:58)-The International Nail Society’s hopes for the future
(19:00)-Atopic dermatitis in adolescents
(20:08)-Presentation and treatment of benign nail unit tumours
(23:32)-Doctor-patient relationship in dermatology
(25:23)-Innovations in the field
(26:57)-Three wishes for the future of healthcare
In this episode, moderator George Cooper, sits down with the brilliant minds of Professor Stacey Cohen and Dr. Jeff Sharman. Together, they delve into the fascinating world of Monoclonal Antibody Biosimilars and their significant impact on the field of Oncology, with a particular focus on Lymphoma and Colorectal Cancer. Join us as our expert panel explores the utilization of Monoclonal Antibody Biosimilars in the treatment of these cancers, shedding light on their efficacy and safety. Drawing from their extensive experience and knowledge, Professor Cohen and Dr. Sharman also share their insights on the prevailing attitudes towards this approach, while highlighting the key aspects of the current consensus within the medical community. This episode also offers a glimpse into the future prospects of Monoclonal Antibody Biosimilars, including the anticipated uptake and potential advancements in the field. Professor Stacey Cohen Associate Professor at the Clinical Research Division, Fred Hutch Cancer Centre as well as an Associate Professor at the Division of Oncology, University of Washington. Professor Cohen is a specialized medical oncologist focusing on GI cancers, including colon, rectal, early-onset, and hereditary types. Her research explores the influence of genetics on treatment choices, encompassing hereditary gene alterations, tumor genetic changes, and novel disease markers. Dr. Cohen aims to personalize treatment decisions for her patients and the wider cancer community, maximizing efficacy while minimizing side effects. She values establishing enduring patient relationships and participating in collaborative decision-making processes. Doctor Jeff P Sharman Director of Research at the Willamette Valley Cancer Institute as well as the Medical Director of Hematology Research for The US Oncology Network. Dr. Sharman, the research director at the Willamette Valley Cancer Institute and the medical director of hematology research for The US Oncology Network, possesses extensive knowledge and expertise in the latest scientific advancements across various cancer types. His notable contributions to treatment progress and extensive publication history in esteemed scientific journals, such as the New England Journal of Medicine, Journal of Clinical Oncology, and Blood, highlight his expertise. Through his research program in Eugene, he has garnered global recognition in diverse cancer fields and presented his findings at major conferences in the US, Asia, and Europe. Dr. Sharman's research has facilitated WVCI's access to exciting new areas of research, including immunotherapy, targeted therapy, and personalized medicine. This podcast was funded by an educational grant from Pfizer, who has had no input to the creation of this educational podcast.
This podcast episode explores the increasing global burden of dengue disease, focusing on changing demographics in endemic areas and the mounting risk of the disease in traditionally non-endemic areas. Moderated by Sue Saville, an independent health journalist, experts Tikki Pangestu, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, and João Bosco Siqueira, Federal University of Gois, Brazil, discuss the dangers of arboviral diseases, their impact on the healthcare ecosystem, and prevention strategies.
This podcast was funded by Merck Sharp & Dohme LLC
This week, Jonathan is joined by Eva Parker, Assistant Professor of Dermatology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. They explore the impact of climate change on dermatological diseases such as skin cancer, atopic dermatitis, and psoriasis. The pair also discuss how the skin is affected by rising temperatures, ultraviolet radiation, and air pollution, and further dive into diversity and inclusion in the dermatology field, and how political issues can affect healthcare.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:45)-Impact of climate change on dermatology and the skin
(04:23)-Encouraging more people to take skin cancer seriously
(06:30)-American Academy of Dermatology (AAD) Expert Resource Group (ERG) on Climate Change and Environmental Affairs
(07:54)-Revelations being published
(11:05)-Health issues as a political issue
(12:40)-Impact of climate change atopic dermatitis and mental health comorbidities
(15:09)-Minimising our impact on climate change
(18:40)-Chagas disease
(22:48)-How skin colours affects skin presentations
(24:50)-Diversity, equality, and inclusion in healthcare and dermatology
(27:25)-Three wishes for healthcare
This podcast episode explores new advances in treating obstructive hypertrophic cardiomyopathy (HCM) and the role of myosin inhibitors, and provides an overview of the EXPLORER-HCM and VALOR-HCM clinical trials.
Iacopo Olivotto, University of Florence, Italy, first discusses unmet medical needs, specifically regarding the unmet needs of patients and gaps in current treatment methods. The discussion then centres around the mechanism of action of myosin inhibitors, a first-in-class drug for HCM, recently approved by the European Medicines Agency (EMA).
The findings of current clinical trials are outlined, with results being linked to a reduced need for septal reduction therapy, in addition to improved quality of life for patients. Finally, case studies are presented, discussing the impact of treatments on the lives of patients with HCM, and how to best integrate new treatments into current practice.
Listen to our latest podcast, featuring expert guests Domenica Lorusso, Catholic University of Rome, Italy and Nicole Concin, Medical University of Innsbruck, Austria. This episode discusses key findings from recent research into predictive biomarkers in endometrial cancer, specifically focusing on the potential for these biomarkers to inform clinical decision making.
This podcast was funded by a medical educational grant from GSK, with the purpose of enhancing the fundamental understanding of oncology specialists of key data and the latest advancements in endometrial cancer care.
Morag Griffin, Haematology Consultant, Leeds University Teaching Hospitals, UK, joins Jonathan to discuss rare haematological conditions, such as aplastic anaemia and paroxysmal nocturnal haemoglobinuria, as well as their treatments. They also discuss how vaccination response is affected by these diseases.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:13)-What led Griffin into haematology
(02.00)-How Griffin’s Master’s degree in leadership helped her throughout her career
(03.10)-Paroxysmal nocturnal haemoglobinuria (PNH)
(09.13)-Griffin’s research on biomarkers and laboratory assessments for monitoring the treatment of patients with PNH
(12:44)-Aplastic anaemia
(16:43)-Importance of international collaboration
(19:34)-How aplastic anaemia and PNH affect vaccination responses
(23:45)-Histiocytic disease
(26:23)-Future research in haematology
(29:02)-Three wishes for the future of healthcare
This week’s episode dives into racial disparities in healthcare and the field of urology, with a focus on prostate and bladder cancer. Jonathan and Samuel Washington, University of California San Francisco (UCSF), USA, discuss equality and equity in healthcare, uncovering how racial disparities affect the diagnosis and treatment of urological tumours, particularly in African American men. The pair also speak about which groups are more at risk of experiencing adverse outcomes, the changes needed to ensure better care is available to these patients, and how racial disparities affect medical education.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:58)-Inspiration which led Washington to work in urologic oncology
(02:42)-“Urologic personality” traits
(04:01)-Machine-learning algorithms in estimating occurrence of lymph node cancer
(06:26)-Dietary and lifestyle factors influencing patient outcomes
(08:06)-Healthcare disparities in treating genitourinary diseases
(09:45)-Changes needed to make outcomes equivalent for patients of different races
(12:52)-Societal and political factors interacting with healthcare
(15:04)-Socioeconomic factors impacting healthcare use after bladder removal
(16:59)-Equity and equality in healthcare: health literacy and shared decision-making
(18:42)-Tailoring patient communications in prostate cancer screening
(20:00)-Partner-supported treatment decisions
(21:03)-Racial and ethnic differences in medical student training
(22:23)-Three wishes for the future of healthcare
In this podcast episode, moderator George Cooper is joined by Dr Pavan Najran, Clinical Lead for Interventional Radiology at the Christie Hospital NHS Foundation Trust. During the episode, the distal radial method is explored. Its distinctions from conventional radial methods are outlined, and its applications within the radiology field highlighted.
Pavan Najran, Clinical Lead for Interventional Radiology and Consultant Clinical and Interventional Radiologist, The Christie Hospital NHS Foundation Trust, Manchester, UK, provides guidance on performing the distal radial method for radiology, covering topics ranging from the room set-up to achieving haemostasis. Najran also discusses solutions for situations involving thrombosis in the distal radial artery. The conversation further highlights the advancements offered by the distal radial method in comparison to the traditional radial approach, providing perspectives into how it enhances patient experience. Additionally, Najran addresses the common challenges encountered when implementing the distal radial method and offers valuable insights on how to overcome them.
The publication of this podcast was funded by Merit
The suggestions and other information, which may include both Merit and third-party products, are for the practitioner’s convenience and for general information purposes only. This information does not constitute medical or legal advice, nor is it meant to endorse or guarantee the suitability of any of the referenced products or methods for any specific patient or procedure. Before using, refer to the Instructions for Use (IFU) for indications, contraindications, warnings, precautions, and directions for use.
This episode explores how social media and cognitive psychology can be used to optimise patient–doctor relationships, and enhance teaching and diagnosis in dermatology and dermatopathology. Christine Ko, Professor of Dermatology and Pathology, Yale University, New Haven, Connecticut, USA, joins Jonathan for a second podcast episode where they discuss Ko’s publications, dive deeper into cognitive bias and visual perception in clinical practice, and consider the challenges in humanising medicine in dermatology and dermatopathology.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(00:30)-Using social media to learn about patient experience
(04:12)-The role of visual perception in dermatology and dermatopathology
(09:05)-Cognitive bias and its implications in dermatology
(13:15)-Discussing Ko’s book, ‘How to Improve Doctor-Patient Connection’, and the importance of building good relationships
(19:37)-Challenges in humanising medicine in dermatology and dermatopathology
(26:03)-Three wishes for the future of healthcare
Christine Ko, Professor of Dermatology and Pathology, Yale University, New Haven, Connecticut, USA, joins Jonathan to discuss her early career and the ever-increasing burden of skin cancer. Ko also introduces Jonathan to the field of transplant dermatology.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:15)-Ko’s journey into dermatology and dermatopathology
(04:31)-Squamous cell carcinogenesis
(08:45)-Why skin cancer is becoming more common
(11:11)-Transplant dermatology
(14.02)-Changes in education
This podcast explores the burden of chronic inflammation for patients with chronic obstructive pulmonary disease (COPD) and its negative impact on quality of life. The following experts in the field review diagnosis, discussing what stage COPD is typically diagnosed at and how it presents differently to asthma, alongside further insights into patient perspective including what can be improved at the outset of diagnosis.
Guest Speakers:
- Claus Vogelmeier, Professor of Medicine and Head of the Department of Pneumology, University Hospital Marburg, Germany
- Nicola Hanania, Professor of Medicine and Section Chief of Pulmonary, Critical Care and Sleep Medicine, Ben Taub Hospital, Houston, Texas
- John Linnell, Patient Advocate
The publication of this podcast was funded by Sanofi.
In this episode, Jonathan is joined by Richard Cohen, Chief of Surgery at Cleveland Clinic London, UK, to dive into a plethora of gastrointestinal disorders, including irritable bowel syndrome, colorectal cancer, diverticulitis, and haemorrhoids, and covering prevention and diagnosis, as well as surgical treatments. The pair explore the role of minimally invasive and robotic surgery in the present and future, as well as the role of regenerative medicine. They further cover the importance of screening for colorectal cancer, and current available techniques.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:50)-Cohen’s path to colorectal surgery
(07:10)-Fixing anal fistulas
(13:15)-Colon cancer screening and diagnosis
(17:30)-Colonoscopy
(18:30)-The polyp-cancer sequence
(19:55)-Innovations in bowel surgery
(24:20)-Irritable bowel syndrome
(26:45)-Diet in bowel disease
(28:40)-Diverticular disease
(32:05)-Haemorrhoids
(36:00)-Three wishes for the future of healthcare
Arthur Burnett joins Jonathan Sackier on this episode of the EMJ podcast to discuss controversy in urology and individuals suffering in silence due to ‘embarrassing’ medical conditions.
Edwina Brown, Consultant Nephrologist at Imperial College Renal and Transplant Centre at Hammersmith Hospital, London, UK, and Honorary Professor of Renal Medicine at Imperial College London, UK, joins Jonathan to discuss how nephrologists can take a more person-centred approach to medical care and decision-making. Brown also details her goals as President of the International Society for Peritoneal Dialysis (ISPD), and how she wants it to become more inclusive.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:06)-A patient-centric approach in nephrology
(03:51)-Brown’s goals as President of the ISPD
(07:27)-A 30,000-foot view of peritoneal dialysis
(10:18)-Peritoneal dialysis from a global perspective
(18:02)-Kidney failure in an aging population
(23:07)-Controversies in nephrology and how they are being addressed
(27:04)-End-of-life renal care and bereavement support
(29:38)-The changing landscape of women in nephrology
(33:12)-Brown’s three wishes for the future of healthcare
This episode focuses on approaches toward the World Health Organization (WHO)’s goal for eliminating hepatitis worldwide by 2030, and the importance of reliable information when making informed healthcare decisions. Jonathan is joined by Raymond Chung, Director of the Hepatology and Liver Center at Massachusetts General Hospital, Boston, USA, and Professor of Medicine at Harvard Medical School. The pair discuss technological advances and innovations in the field of hepatology, such as the use of living donors in liver transplantation.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:04)-What led Chung into medicine and specifically hepatology
(04:28)-Chung’s Research into hepatitis B and C infection
(08:35)-Hepatitis awareness, testing, and available treatments
(16:38)-American Association for the Study of Liver Diseases’ achievements during Chung’s presidency
(25:21)-Liver transplantation
(32:03)-Cost of care in hepatology
(33:58)-Chung’s research on COVID-19
(37:25)-Research Chung is most proud of
(41:03)-Chung’s three wishes for healthcare
This week, Jonathan is joined by Laura Sycuro, University of Calgary, Alberta, Canada, to explore the microbiome, providing insights into what it means and how it affects mother and child. The pair discuss the interaction between human microbiota and disease, microbial imbalances and how to correct them, and how microbial transmission from mothers impacts the lifelong health of their children. They further dive into the vaginal microbiome and chorioamniotic infection in pre-term labour.
Use the following timestamps to navigate the content discussed in this episode:
(00:00)-Introduction
(02:16)-Research on bobtail squid at the University of Hawaii, USA
(05:48)-Defining the microbiome
(10:56)-Understanding the microbiome
(11:46)-Research into the maternal microbiome, and when bacterial colonisation begins for the infant
(16:42)-Microbiome and the gut–brain axis
(20:00)-Key messages from Sycuro’s work investigating genetic and genomic approaches to understanding interaction between human microbiome and disease
(22:58)-The vaginal microbiome in other species
(25:09)-Chorioamniotic infection in pre-term labour
(29:16)-Metagenomics: detecting and assembling genomes of uncultivated species and strains
(32:45)-Emerging areas of research, and Sycuro’s personal focus in future
(36:03)-Three wishes for the future of healthcare
This podcast explores the current burden of haemophilia; namely the geographical prevalence and treatment regimes, as well as examining novel gene therapies for haemophilia. Steven Pipe, Professor of Pediatrics and Professor of Pathology, University of Michigan, Ann Arbor, USA, and Radek Kaczmarek, Assistant Research Professor of Pediatrics, Indiana University School of Medicine, Indianapolis, USA, review the new generation of gene therapies, discussing how the novel therapeutics differ from current treatments.
This was funded by an educational grant from Pfizer, who had no input to the creation of this educational podcast.
Bishwanath Ghosh Dastidar, Director of the IVF Program at Ghosh Dastidar Institute for Fertility Research, Kolkata, India, joins Jonathan to discuss the continually shifting field of IVF. Dastidar also discusses reproductive healthcare in India, specifically planning for the future through the development of innovative strategies to bridge healthcare gaps.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(03:10)-How the birth of the world’s first IVF babies influenced Dastidar’s career choice
(06:50)-Personalised physiologic and mild stimulation treatments
(09:08)-Major breakthroughs in IVF in the past 15 years
(12:28)-The need for a shift in research focus in IVF and women’s health
(19:47)-The adoption of virtual healthcare and telemedicine
(25:06)-Unmet healthcare needs for females
(31:16)-Three wishes for the future of healthcare
This episode dives deep into the meaning of physical, emotional, and spiritual wellbeing, and how chronic excessive workload can impact a physician’s wellbeing. Jonathan is once again joined by Lalith Wijedoru, consultant emergency paediatrician and Founder of Behind Your Mask, UK. The pair discuss approaches to improve physical wellbeing, such as musical therapy, and how moral distress can cause burnout. Further topics of conversation include the welfare of children, the importance of skin-to-skin contact for maternal and paternal bonding, and how abuse can affect children long-term.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:10)-Defining wellbeing
(02:30)-Factors that affect wellbeing
(04:40)-Wijedoru’s path into wellbeing
(07:20)-Wijedoru’s approach to physical wellbeing
(10:15)-Importance of physical touch in wellbeing
(13:10)-Moral distress
(14:35)-Paediatric safeguarding
(17:00)-Impact of music on wellbeing
(20:20)-Three wishes
In this podcast, an experienced conference and webinar moderator is joined by two doctors in the field of paediatric infectious diseases: David Greenberg and Maria Hemming-Harlo.
In this podcast, our guest experts provide information and their perspectives on the following topics:
- The disease burden of rotavirus
- The related morbidity and mortality of rotavirus
- How rotavirus is transmitted
- The clinical picture of rotavirus infection
- The evidence supporting routine vaccination with RotaTeq (Rotavirus Vaccine, Live, Oral, Pentavalent)
This podcast was funded by Merck Sharp & Dohme LLC.
Below please find the reference list for Vax Voices, Podcast 1: The Global Burden of Rotavirus Disease and Evidence Supporting Routine Vaccination With RotaTeq to ensure listeners can further explore the content discussed.
View the product information and indication for RotaTeq here.
View the Select Safety Information from MSD below.
Select Safety Information
RotaTeq should not be administered to infants with a demonstrated history of hypersensitivity to the vaccine or any component of the vaccine.
Infants with a history of intussusception or who have congenital malformation of the gastrointestinal tract that could predispose infants to intussusception should not receive RotaTeq.
Infants with Severe Combined Immunodeficiency Disease or SCID should not receive RotaTeq.
Administration of RotaTeq should be postponed in infants suffering from acute severe febrile illness. The presence of a minor infection is not a contraindication for immunisation.
The administration of RotaTeq should be postponed in subjects suffering from acute diarrhoea or vomiting.
No safety or efficacy data are available from clinical trials regarding the administration of RotaTeq to infants who are potentially immunocompromised.
Cases of gastroenteritis associated with vaccine virus have been reported post marketing in infants with severe combined immunodeficiency.
Vaccine virus transmission from vaccine recipient to nonvaccinated contacts has been reported. Caution is advised when considering whether to administer RotaTeq to individuals with immunodeficient contacts.
In post-marketing experience, intussusception (including death) and Kawasaki disease have been reported in infants who have received RotaTeq.
As a precaution, healthcare professionals should follow-up on any symptoms indicative of intussusception (severe abdominal pain, persistent vomiting, bloody stools, abdominal bloating and/or high fever) since data from observational studies indicate an increased risk of intussusception, mostly within 7 days after rotavirus vaccination. Parents/guardians should be advised to promptly report such symptoms to their healthcare provider.
The level of protection provided by RotaTeq is based on the completion of all 3 doses. As with any vaccine, vaccination with RotaTeq may not result in complete protection in all recipients.
HQ-ROT-00133 | 02/23
Podcast References:
1.Nelson R. COVID-19 disrupts vaccine delivery. Lancet Infect Dis. 2020;20(5):546.
2.Centers for Disease Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable Diseases. 14th ed. Chapter 19: Rotavirus. Available at: https://www.cdc.gov/vaccines/pubs/pinkbook/rota.html. Last accessed: 6 March 2023.
3.Dormitzer PR. "Rotaviruses," Mandell GL, et al, eds. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 9th ed. Elsevier Saunders; 2019:1983-96.
4.Centers for Disease Control and Prevention (CDC). Rotavirus. Clinical information. 2021. Available at: https://www.cdc.gov/rotavirus/clinical.html. Last accessed: 13 October 2022.
5.Troeger C et al. Rotavirus vaccination and the global burden of rotavirus diarrhea among children younger than 5 years. JAMA Pediatr. 2018;172(10):958-965. Erratum in: JAMA Pediatr. 2022;176(2):208.
6.GBD Diarrhoeal Diseases Collaborators. Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Infect Dis. 2017;17(9):909-948. Erratum in: Lancet Infect Dis. 2017 Sep;17(9):897.
7.Van Damme P et al. Rotavirus vaccines: considerations for successful implementation in Europe. Lancet Infect Dis. 2006;6(12):805-12.
8.Paul MO, Erinle EA. Influence of humidity on rotavirus prevalence among Nigerian infants and young children with gastroenteritis. J Clin Microbiol. 1982;15(2):212-5.
9.Finnish Institute for Health and Welfare. Infectious diseases and vaccines: rotavirus vaccine. 2020. Available at: https://thl.fi/en/web/infectious-diseases-and-vaccinations/vaccines-a-to-z/rotavirus-vaccine. Last accessed: 16 September 2022.
10.GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117-71.
11.Franco MA et al. Immunity and correlates of protection for rotavirus vaccines. Vaccine. 2006;24(15):2718-31.
12.Gentsch JR et al. Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs. J Infect Dis. 2005;192(Suppl 1):S146-59.
13.Merck & Co. RotaTeq®. Prescribing information. 2022. Available at: https://www.merck.com/product/usa/pi_circulars/r/rotateq/rotateq_pi.pdf. Last accessed: 4 January 2023.
14.European Medicine Agency (EMA). RotaTeq. Summary of product characteristics. 2022. Available at: https://www.ema.europa.eu/en/documents/product-information/rotateq-epar-product-information_en.pdf. Last accessed: 4 January 2023.
15.Velasquez-Portocarrero DE et al. Head-to-head comparison of the immunogenicity of RotaTeq and Rotarix rotavirus vaccines and factors associated with seroresponse in infants in Bangladesh: a randomised, controlled, open-label, parallel, phase 4 trial. Lancet Infect Dis. 2022;22(11):1606-16.
16.Cortese MM, Parashar UD; Centers for Disease Control and Prevention (CDC). Prevention of rotavirus gastroenteritis among infants and children: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2009;58(RR-2):1-25.
17.Vesikari T et al.; Rotavirus Efficacy and Safety Trial (REST) Study Team. Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine. N Engl J Med. 2006;354(1):23-33.
18.Vesikari T et al. Efficacy of a pentavalent rotavirus vaccine in reducing rotavirus-associated health care utilization across three regions (11 countries). Int J Infect Dis. 2007;11(Suppl 2):S29-35.
19.Heyse JF; REST Study Team. Evaluating the safety of a rotavirus vaccine: the REST of the story. Clin Trials. 2008;5(2):131-9.
20.World Health Organization (WHO). Rotavirus vaccines: WHO position paper. Wkly Epidemiol Rec. 2021;96(28):301-20.
This episode explores the challenges encountered in different healthcare settings and how storytelling can help promote wellbeing in the workplace. Lalith Wijedoru, consultant emergency paediatrician and Founder of Behind Your Mask, UK, joins Jonathan to discuss the power of storytelling within the workplace to facilitate emotional wellbeing. Wijedoru delves into the prevalence of burnout following the COVID-19 pandemic, and also speaks about working in low-resource healthcare settings across Asia.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:34)-What inspired Wijedoru to pursue a career in paediatric emergency medicine
(02:35)-Global child health
(04:13)-Socioeconomic determinants of health around the world
(05:50)-Working in low-resource settings, and the impact this had on Wijedoru’s worldview
(09:04)-The founding of Behind Your Mask, and how storytelling plays a part in wellbeing
(12:08)-How a storytelling session works, and Wijedoru’s role as a facilitator in storytelling sessions
(16:10)-The role of storytelling role in emotional wellbeing
(18:05)-Burnout in healthcare settings
(20:37)-NHS Voices of COVID-19 project
(24:15)-Concept of human connection
This episode focuses on endometriosis and discusses current and new innovative ways for diagnosing this condition. Christine Metz, Donald and Barbara Zucker School of Medicine, Hempstead, New York, USA, joins Jonathan to discuss innovations in the field and the challenges around obtaining funding for women-centred conditions. Metz also discusses the ROSE study, which is investigating new ways for non-invasive diagnosis of endometriosis. Find out more about the ROSE study from the Feinstein Institutes for Medical Research and Endometriosis Foundation of America (EndoFound).
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(01:51)-Metz’s origin story and path to endometriosis research
(04:01)-Defining moments in women’s health research
(05:25)-Explaining endometriosis
(07:47)-Endometriosis research: the ROSE study
(10:57)-Delays in diagnosis
(12:44)-Recruitment for the ROSE study
(13:15)-Endometriosis awareness
(14:15)-Treatment options and accessibility
(16:58)-Award-winning research on a non-invasive diagnostic test for endometriosis
(19:28)-The ROSE II clinical trial
(20:54)-Gaps in women’s health research
(22:20)-Advancing Women in Science and Medicine
(26:32)-Education and mentoring
(29:07)-Three wishes
This EMJ podcast discusses the gold standard of care for allergic rhinitis, and features Philip Rouadi, Professor of Otolaryngology and Head & Neck Surgery, Eye & Ear University, Beirut, Lebanon. Using his expertise as President of the Pan Arab Society of Allergy, Asthma and Immunology (PASAAI) and as a Member of the House of Directors at the World Allergy Organization (WAO), Rouadi outlines the aetiology and impact allergic rhinitis has on patients, as well as delving into some of the challenges associated with diagnosing this condition.
This podcast, included any videos, attachments or links therein, is for the sole use of healthcare professionals and cannot be distributed, shared or disclosed further. This educational content is intended for scientific exchange and non-promotional purposes only. This educational content has been fully sponsored by Menarini Group and the content does not necessarily reflect the views of Menarini Group
Alex Ford, Professor and Consultant Gastroenterologist at St James’s University Hospital, Leeds, UK, joins Jonathan to discuss disorders of gut–brain interaction. Ford explains his specific interest in functional gastrointestinal disorders and recent revisions of their aetiology, as well as how conditions of gut–brain interaction affect quality of life and social functioning.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(03:16)-Causes of disorders of gut–brain interaction
(06:00)-Impact of gut–brain interaction disorders on quality of life
(07:32)-The cost-effectiveness of eradicating H. pylori in certain conditions
(10:15)-How Ford’s MD thesis impacted the National Institute for Health and Care Excellence (NICE) guidelines for the management of dyspepsia
(12:15)-Ford’s experience as a Post-doctoral Fellow at McMaster University in Canada
(14:24)-The effectiveness of antidepressants in the treatment of irritable bowel disease
(16:50)-Prevalence of disorders gut–brain interaction depending on sex and ethnicity
(19:33)-Effectiveness of the low FODMAP diet on irritable bowel disease
(23:20)-Mental health disorders in patients with inflammatory bowel disease
(28:30)-Ford’s three wishes for global healthcare
Chronic lung disease currently accounts for a large percentage of deaths in both males and females. This podcast challenges stereotypes and provides insights into the differences in respiratory care between sexes. Featured on this episode is Nicolas Roche, Professor of Respiratory Medicine, Paris Descartes University, and the Department of Respiratory and Intensive Care Medicine, Cochin-Broca-Hotel-Dieu Hospital Group, Paris, France.
Roche gives an overview on chronic obstructive pulmonary disease (COPD), describing the leading causes and burden of this condition, and addressing gender differences and the perception that this is a predominantly male disease. Physical, social, and lifestyle differences are all considered in relation to common lung diseases such as asthma and bronchiectasis. Roche also uses his expertise to outline several important clinical considerations, including initiatives to combat underdiagnosis of COPD in females, and the steps that can be taken to improve disparities in respiratory care based on sex and gender.
This content is sponsored by Philips.
In this episode, Jonathan is joined by Adam Brown, Rheumatologist at the Cleveland Clinic in Ohio, USA. They discuss Brown’s unconventional teaching practices and how he has been awarded the teacher of the year several times at the Cleveland Clinic. They also delve into the history of rheumatology, focusing on specific rheumatological conditions such as gout, and his recent talk at the American College of Rheumatology (ACR) meeting.
Use the following links to navigate the key topics discussed in this episode:
(00:00)-Introduction
(02:51)-Adam’s path into rheumatology
(06:44)-Travel and learnings from being abroad
(08:47)-Surfing in Australia
(11:37)-The King’s disease
(18:55)-Online rheumatology resources
(20:45)-Rheumatology made ridiculously simple
(27:04)-The societal impacts of plagues and pandemics throughout history
(35:24)-Whipple disease
(39:35)-Three wishes for the future of healthcare
Giovanni Adami, Rheumatologist at the University of Verona, Italy, joins Jonathan to discuss a range of topics, from metabolic bone disease to rheumatoid arthritis and osteoporosis, and provide an overview of causes and symptoms, as well as treatments. They further dive into the impact of rheumatoid arthritis on patients and their quality of life, as well as the association between air pollution and rheumatoid arthritis flares.
Use the following timestamps to navigate the topics discussed in this episode:
(00:00)-Introduction
(02:30)-Adami's origin story
(03:14)-Experiences from Alabama, USA, and research carried out there
(06:36)-Osteoporosis and bisphosphonates
(07:05)-Fragility fractures in diseases requiring glucocorticoids
(10:14)-Metabolic bone disease and its causes
(13:24)-How to reduce the number of patients with metabolic bone disease
(14:24)-Incidence of hip fracture worldwide
(16:29)-Positive effects of TNF-α inhibitors
(19:21)-Benefits of Vitamin D for older patients
(20:04)-Links between rheumatoid arthritis and osteoporosis
(23:13)-Arthritis types and causes
(25:57)-Gout
(28:55)-Impact of arthritis diagnosis on patients
(30:54)-Association between air pollution and disease activity
(36:47)-Three wishes for the future of healthcare
In this third podcast, Ali Mobasheri and Daniel White focus on late-stage OA, when the burden is high for both the individual and society. Our two speakers advise patients, caregivers, and physicians about how OA disease should be managed in the end stages, when to engage patients for surgical options, and whether this is appropriate or not according to other comorbidities.
This content has been supported by Viatris
On this episode, Jonathan is joined by Noel Morgan, Professor of Endocrine Pharmacology, University of Exeter, UK. The pair discuss Morgan’s extensive research in diabetes, including his research on islet biology and signalling mechanisms regulating pro-inflammatory and anti-inflammatory processes in β-cells in Type 1 diabetes. They further discuss areas of research that excite and frustrate him, how we can change beliefs and behaviours associated with diabetes, and the future of diabetes research.
Use the following timestamps to navigate the topics discussed in this episode:
00:00-Introduction
02:00-Morgan's origin story
03:30-Experiences from Nashville, USA
06:00-Islet biology
08:00-Insulin secretion control
12:25-Aetiology and differences between Type 1 and Type 2 diabetes
15:10-The largest collection of rare pancreas samples in the world
17:50-Different ‘types’ of Type 1 diabetes
20:15-Pro-insulin
22:35-To B or not to B?
24:35-Rituximab
26:00-Dorothy Hodgkin Lecture
28:00-The global obesity epidemic and changing behaviour
31:45-The war on obesity
33:40-A longer, unhealthy life?
34:45-Exciting topics and immunotherapy
36:50-Three wishes
This informative podcast spotlights the current treatment landscape of hypertrophic cardiomyopathy (HCM), detailing typical diagnosis and outlining the use of echocardiography for obstructive HCM.
This podcast was sponsored by Myokardia and Bristol Myers Squibb.
In this episode, Jonathan is joined by Chris Wincup, Versus Arthritis Clinical Research Fellow in Rheumatology, Department of Rheumatology, University College London, UK. They discuss the current treatments for systemic lupus erythematosus (SLE), as well as symptoms. They also consider mental health in patients with SLE, and the effect that the COVID-19 pandemic has had on patients with SLE and autoimmune diseases.
In this episode, Jonathan is joined by Shivam Joshi, Adjunct Clinical Assistant Professor at the Departments of Medicine and Nephrology, New York University (NYU) Grossman School of Medicine, New York, USA, and Nephrologist at Veterans Affairs in Orlando, Florida, USA. They discuss the benefits and disadvantages of certain diets, with a particular focus on the effects of keto, paleo, and low carbohydrate diets on diabetes. They also cover potassium restriction in patients with kidney disease, climate change and dialysis, and burnout in healthcare professionals.
For more information on the benefits of plant-based diets, please head over to Joshi’s website by clicking here. You can also find him on twitter at @SJoshiMD.
Glaucoma is one of the leading causes of irreversible blindness worldwide and continues to remain under diagnosed and under treated. The objective of this podcast is to educate ophthalmologists on Glaucoma condition to advance eye care, to enhance clinical knowledge, improve clinical skills, improve practice behavior, and improve patient outcomes.
The publication of this podcast was sponsored by Viatris
This week, Jonathan is joined by Ai Lyn Tan, Associate Professor at the University of Leeds School of Medicine, UK, for discussion of the different classifications of arthritis. The pair also speak about the process of clinical trials, how these are translated into clinical practice, the emotional burden of living with rheumatoid arthritis, and the benefits of physical activity for patients with arthritis.
In this second podcast, Ali Mobasheri and Daniel White discuss the importance of the patient actively engaging with OA post-diagnosis, and living well with the disease in its early to middle stages. The speakers also share their expert advice to help patients achieve the best possible quality of life. Additionally, practitioners are guided towards adopting a more proactive approach to OA. Emphasis is placed on the importance of multidisciplinary care, and the impact that patient self-empowerment and a positive mindset can have on managing chronic pain. Additionally, practitioners are guided towards adopting a more proactive approach to OA disease.
This content has been supported by Viatris
This week, Jonathan is joined by Monica Jain, Assistant Professor of Surgery, Division of Minimally Invasive, Gastrointestinal and Endocrine Surgery, and Surgical Innovation Officer at the Cedars-Sinai Health System, Beverly Hills, California, USA. They discuss the development of new healthcare innovations, human-centred design, and the role of women in biomedical engineering and technology.
Angela George, Consultant Medical Oncologist, Consultant in Oncogenetics, and Clinical Director of Genomics, The Royal Marsden Hospital, London, UK, joins Jonathan to discuss the importance of personalised cancer treatment for patients. George explains her specific interest in germline and somatic mutations in cancer, the hereditary and genetic links in different cancer types, and her focus on genomics research to improve outcomes for patients during and post-treatment.
This week, Jonathan Sackier is joined by Robert Cowan, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Palo Alto, California, USA. The pair dive deep into the causes, manifestations, prevention, and treatment of headaches and migraine, discussing differences observed in brain anatomy. They discuss remote electrical neuromodulation for the prevention of migraine, stigmas associated with headaches and migraine, the differences between episodic and chronic migraine, and the manifestations and nature of auras.
In this first podcast, Ali Mobasheri and Daniel White discuss why OA is a serious disease and how it’s burden of disease impacts individuals and society. Conversation focuses on the importance of early-stage diagnosis and why it is an important step in encouraging OA patients to live as disability free as possible. The experts also address how the initial stage of OA condition is often stigmatised, ignored, or downplayed by patients, whilst at the same time recognizing how early lifestyle modification can be an important step in better long-term disease management.
This content has been supported by Viatris
This week, Jonathan is joined by Emma Hallam, Macmillan Consultant Radiographer in Post Treatment & Late Effects at Nottingham Radiotherapy Centre, UK. They discuss Hallam’s career and why her clinic is important for patient who have had cancer. They also discuss the impact that cancer treatment can have on patients, focusing on patient quality of life and symptoms after treatment, and the psychological impact of cancer.
In this podcast, Hallam comments on the Pelvic Radiation Diseases (PRD) Association’s Best Practice Pathway. Find out more by clicking here.
This podcast explores the emerging role of precision medicine in metastatic colorectal cancer (mCRC) and its associated treatment algorithms. Experts in the field, Prof. Sebastian Stintzing and Prof. Erika Martinelli, review the updates from the latest European Society of Medical Oncology (ESMO) Clinical Practice Guideline for the management of patients with mCRC, touching on key developments and how these translate to the current procedures of precision medicine treatment used in clinical practice.
This podcast is not intended for audiences from the UK. Unrestricted funding for the medical education activity has been provided by Pierre Fabre
This week, Jonathan is joined by Steven Feldman, Professor of Dermatology and Pathology at Wake Forest University School of Medicine in Winston-Salem, North Carolina, USA. The pair discuss Feldman’s research into psoriasis and its treatments, including the use of tanning beds, as well as Feldman’s interest in patient compliance and patient satisfaction.
In this EMJ podcast episode, David O’Malley, Director of Gynecologic Oncology, Ohio State University, and the James Comprehensive Cancer Center, Columbus, Ohio, USA, and Christina Fotopoulou, Consultant Gynaecological Oncologist, Queen Charlotte’s & Chelsea Hospital, London, UK, discuss the role of homologous recombination deficiency (HRD) testing, and the progress of poly-ADB ribose polymerase (PARP) inhibitors in ovarian cancer.
The publication of this podcast was funded by a medical educational grant from AstraZeneca with the purpose of enhancing the fundamental understanding of oncology specialists of the role and value of homologous recombination deficiency (HRD) testing and progress in the use of poly(ADP-ribose) polymerase (PARP) inhibitors.
This EMJ podcast explores key topics addressed at the European Respiratory Society (ERS) International Congress 2022, during a symposium entitled ‘Re-IMAGinING the pathway for clinical decision making in rare lung disease – moving towards a united vision’. Focusing on key questions, including the unmet needs in interstitial lung disease, the value of data repositories for enhancing patient care in rare lung diseases, and the impact of exacerbation physiology on imaging parameters The podcast is co-chaired by Charlie Strange, Professor of Pulmonary and Critical Care Medicine, and Daiana Stolz, Medical Director of the Clinic for Pneumology and Professor of Medicine, who are joined by guest Elizabeth Estes, Executive Director of the Open Source Imaging Consortium (OSIC).
This podcast has been sponsored by CSL Behring.
In this episode of the EMJ Podcast, Brigitte Scott hosts Gilles Freyer, Medical Oncologist, Lyon University Hospital, France; and Domenica Lorusso, Associate Professor of Obstetrics and Gynecology, Catholic University of Rome, Italy, and responsible for Clinical Research Development at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy. Freyer and Lorusso provide expert perspectives on the research outcomes, updates, and advancements in ovarian cancer management that were presented at the European Society for Medical Oncology (ESMO) Congress 2022, which took place on 9th–13th September, in Paris, France.
This podcast was funded by a medical educational grant from GSK, with the purpose of enhancing the fundamental understanding of oncology specialists of key data and the latest advancements in ovarian cancer care.
In this week’s episode, Jonathan Sackier is joined by Annalisa Jenkins, a biopharma thought leader with over 25 years of experience in the industry. The pair discuss Jenkins’ time in the Royal Navy, her role as non-executive director of Genomics England, and how connecting human and financial capital can help create an environment conducive to success.
On this week’s episode of the EMJ Podcast, our host Jonathan is joined by Bruce Gewertz, Surgeon-in-Chief, Chair of the Department of Surgery, Vice-Dean for Academic Affairs, and Vice-President for Interventional Services at Cedars-Sinai Health System, Los Angeles, USA. They discuss Gewertz’s 40-year-long career in vascular surgery and academic medicine, as well as pertinent topics including burnout in healthcare professionals, self-doubt, and ensuring the establishment of a work-life balance. An anecdote about Bruce and Jonathan’s mutual friend, George Berci, who is still practicing at the age of 101, addresses fulfilment in medicine.
In this special episode, Evgenia Koutsouki, Editor of the EMJ family of journals, reflects on the most interesting and noteworthy moments of past 3 months on the EMJ podcast. Covering topics from research into childhood leukaemia to a deep dive into consciousness, this podcast looks back on the most fascinating insights provided by our guests.
On this week’s episode of the EMJ Podcast, our host Jonathan Sackier is joined by Karen Ousey, Professor of Skin Integrity and Director of the Institute for Skin Integrity and Infection Prevention at the University of Huddersfield, UK. They discuss Ousey’s career in wound healing, how she came to be a visiting adjunct professor in Australia and Ireland, and the importance of education. They also discuss antimicrobial resistance and the problems that it is causing in treating certain conditions.
In this week’s episode, Jonathan is joined by Peter Samuelson, Co-founder of the Starlight Children’s Foundation, Los Angeles, California, USA, and Co-founder and President of First Star, Oxford, UK. The pair discuss the origins of these fantastic charities and touch on Samuelson’s work in setting up Everyone Deserves a Roof (EDAR) in Los Angeles, California, USA, in 2005, which aims to tackle homelessness.
This Podcast, hosted by Brigitte Scott, explores the important role ultrasound has in Rheumatology. Join experts Lene Terslev, Chief Consultant in Rheumatology at Rigshospitalet, and Professor of Rheumatology at Copenhagen University, Denmark, and Esperanza Naredo, Rheumatologist and Associate Professor at Universidad Autónoma de Madrid, Spain, as they discuss their experiences and expertise in using ultrasound in their daily practice, how ultrasound enhances the clinical care they provide, and the benefits of using this technique for their patients.
This podcast was supported by GE Healthcare. The views and opinions of the speakers are not necessarily of GE Healthcare or EMJ.
In this week’s episode, Jonathan Sackier is joined by Ariel Halevy, Chief of Surgery at Assaf Harofeh Medical Center in Be’er Ya’akov, Israel. The pair reflect on Halevy’s career and share anecdotes from the operating room, looking back on his time working as a general surgeon. From stories on diagnostic surgery at a time when imaging was not available to a case report on auto-vampirism, they discuss the highlights of Halevy’s career.
This week, Jonathan is joined by Karin Butler, Project Director at York Health Economics Consortium (YHEC), UK. They discuss Butler’s career in health economics and the role of health economics consultancies and the National Institute for Health and Care Excellence (NICE).
This week, Jonathan is joined by Nebojsa Skrepnik, the Director of Research at Tucson Orthopaedic Institute Research Center in Arizona, USA. They discuss Skrepnik’s career, how he ended up in the USA, and opening his own clinical research centre. The use of cobalt and chromium in prosthetics is also discussed, as well as how difficult-to-treat conditions such as tennis elbow can be treated with platelet-rich plasma.
In this podcast, EMJ are joined by Henrik Grönberg, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden. Focusing on the topic of precision medicine in prostate cancer, this podcast offers valuable insights into the impact that its widespread implementation could have for patients.
Janssen Pharmaceutical Companies of Johnson & Johnson. The views expressed in this podcast are those of the individual speaker and do not necessarily reflect the views of Janssen Pharmaceutical Companies of Johnson & Johnson.
CP-356569, November 2022
This week, our host Jonathan Sackier is joined by Deepali Pal, Assistant Professor in the Department of Applied Sciences and Founder of 3RsLabPal at Northumbria University, UK. The pair discuss Pal’s career and what led her to paediatric oncology, as well as her research to develop low toxicity drugs to treat cancer and patient-specific non-animal technologies.
Host Jonathan Sackier is joined by Steven Laureys, acclaimed neurologist, Founding Director of the GIGA Consciousness Research Unit, Liège University Hospital, Belgium, and Associate Professor at the CERVO Research Centre, Laval University, Québec, Canada. They discuss human consciousness, the ability of the brain to adapt in different situations, and the power of meditation.
Steven Laureys' Website: https://www.drstevenlaureys.org/
The No-Nonsense Meditation Book: https://www.blinkist.com/en/books/the-no-nonsense-meditation-book-en
Interview with Steven Laureys and Matthieu Ricard: https://www.youtube.com/watch?v=2ALsGqR1PHA
Ted Talk - Consciousness in Babies: https://www.ted.com/talks/steven_laureys_consciousness_in_babies
Ted Talk - Brain Concussion: Shake It and You Break It: https://www.youtube.com/watch?v=5nBqLwg2Eug&ab_channel=TEDxTalks
Ted Talk - From Brain to Consciousness: https://www.youtube.com/watch?v=6Qqc_wJS6-Q&ab_channel=TEDxTalks
This podcast explores hematopoietic stem cell transplant in diffuse cutaneous systemic sclerosis (dcSSc) and the potential role of FCR001, an investigational allogeneic cell therapy. We are pleased to be joined by leading sclerosis expert Dinesh Khanna MD, MSc. Dr. Khanna is the Sclerosis Program Director at University of Michigan, USA, Dr. Khanna discusses the symptoms, severity, and progressiveness of sclerosis, focusing on dcSSc. Dr. Khanna further explores the current treatment options, the unmet medical need, and the future of FCR001 and allogeneic stem cell transplants.
This podcast is funded and developed by Talaris Therapeutics, Inc. Talaris Therapeutics is a late-clinical stage cell therapy company that is developing an investigational allogeneic stem cell therapy.
This episode of the EMJ podcast delves into treatment options for patients with intermediate-risk (IR) non-muscle invasive bladder cancer (NMIBC). With a wide range of subgroups that patients with IR NMIBC can fit into, there are many challenges associated with selecting optimal treatment options. Rodolfo Hurle, Chief of the Bladder Unit at IRCCS Humanitas Research Hospital, Milan, Italy, offers his expert perspective on this pertinent topic, as well as insights into the current standard-of-care for patients with IR NMIBC.
Highlighting the risk factors that need to be taken into consideration during the substratification of patients with IR NMIBC, Hurle explains the different approaches to treatment, as well as the duration of maintenance instillations. The potential roles of chemohyperthermia and neoadjuvant therapy for patients with IR NMIBC are explored, with Hurle providing key takeaway insights to listeners.
This week, Jonathan is joined by William Barrett, a talented surgeon. They discuss Barrett’s career in the USA and in other countries where he volunteered, and why he did not continue his career in research. They also talk about the vilification of fats and how social media can be used as a way of alerting healthcare professionals when new research is available, as well as Barrett’s work with Mercy Ships, an international non-profit organisation, where he performed surgeries while on a boat.
In this episode, Jonathan Sackier is joined by Arndt Vogel, committee member of the European Society for Medical Oncology (ESMO). The pair discuss Vogel’s career, his role within the organisation, the recent ESMO Congress, and key themes of cancer care.
Episode 3: Performance and Clinical Utility
Part 1 and 2 of this series covers an introduction into the topic of paediatric tuberculosis (TB) and an exploration of TB diagnostics. To round it off, the third podcast addresses the clinical utility of immune response testing in the management of paediatric TB. Various performance characteristics of the QuantiFERON®-TB Gold Plus (QIAGEN GmbH, Hilden, Germany) assay are shared, including clinical sensitivity compared with bacteriologically-confirmed active TB cases. Finally, the performance of QuantiFERON®-TB Gold Plus in children aged <5 years and 2 years, as well as in immunocompromised children, is highlighted.
The publication of these podcasts was funded by QIAGEN.
Episode 2: Diagnostic
In the first part of this mini-series introduced the topic of paediatric tuberculosis (TB). This is complemented by the second podcast, which explores TB diagnostics including the three commercially available diagnostic tests. Specifically, conversation focuses on the strengths and weaknesses of the tuberculin skin test and interferon-y releases assays for the diagnosis of latent TB infection in children. The role of interferon-y releases assays as a complementary diagnostic tool for active TB in children is described.
The publication of these podcasts was funded by QIAGEN.
Episode 1: Introduction
The first podcast in this three-part series introduces the topic of paediatric tuberculosis (TB) and the concept of latent TB infection (L TBI). Statistics on the risk of progression from LTBI to active TB, as well as the risk of severe TB disease, dissemination, and death in children versus adults are shared.
The publication of these podcasts was funded by QIAGEN.
This week, host Jonathan Sackier is joined by Ricky Bhogal, a Consultant at the Royal Marsden Hospital, London, UK, who specialises in Hepato-Pancreato-Biliary Oncology. The pair discuss the footballing injury which led Bhogal to study medicine, as well as the heady heights which Bhogal has already reached in his career as surgeon, educator, academic, and star of the Channel 4 documentary ‘Super Surgeons: A Chance at Life’.
In this EMJ Podcast, our host Brigitte Scott is joined by Russell Petty, Professor of Medical Oncology, Ninewells Hospital and Medical School, University of Dundee and NHS Tayside, Scotland, UK, and Bianca Devitt, Medical Oncologist, Eastern Health, Australia, who share their perspectives on the multidisciplinary team (MDT) approach in cancer care.
This specialist roundtable discussion examines the key performance indicators for an MDT and the value of the MDT to patients and team members, and focuses on barriers to change in the MDT approach, emerging therapies that could impact the MDT approach, and the evolution of collaboration between clinical and molecular MDTs. To finish, the experts highlight the unprecedented challenges for healthcare systems caused by the COVID-19 pandemic and discuss adaptations to MDT practices that were required as a result, and whether they may continue in the future.
This podcast was funded by a medical educational grant from AstraZeneca, with the purpose of enhancing the fundamental understanding of oncology specialists of the value of a multidisciplinary team approach in the management of patients with cancer.
In this episode, Jonathan is joined by Angela Goyal, a general practitioner and media doctor. Goyal is also the Director of Inspired Medics, an organisation that provides medics with education in lifestyle medicine for patients and medics. They discuss Goyal’s career and how she came to specialise in dermatology, as well as her time volunteering at a hospital in Madhya Pradesh, India. Goyal details lifestyle modification and medicine in treating and preventing certain diseases and disorders.
Chronic cough expert, Dr. Imran Satia, answers questions about chronic cough: the definitions of different types of chronic cough, including refractory chronic cough or unexplained chronic cough (RCC/UCC), patients’ chief complaints when they seek medical consult, and the guidelines-based pathway to diagnose patients with RCC/UCC.
This episode of the EMJ podcast explores various aspects of obstructive hypertrophic cardiomyopathy (HCM), and features expert insights from Antonis Pantazis, Consultant Cardiologist at the Royal Brompton and Harefield hospitals in London, UK, and Chairperson of the European Society of Cardiology (ESC) Working Group on Myocardial and Pericardial Diseases.
This podcast was sponsored by Myokardia and Bristol Myers Squibb.
The attendees can expect two highly interesting interviews with two well-known experts in the field of rheumatoid arthritis, namely Prof. Gerd Burmester and Prof. Mikkel Østergaard.
Prof. Burmester provides expert tips around MTX treatment of RA patients in the context of COVID-19 vaccinations and elaborates the effects of MTX hold on the vaccination response.
Prof. Østergaard elucidates the role of Methotrexate as an anchor drug in the treatment of rheumatoid arthritis, including the possibility of using it in a combination therapy. Furthermore, the advantages of subcutaneous Methotrexate over oral Methotrexate are highlighted.
This podcast has been funded by medac Gmbh, the market leader and innovator in scMTX therapy
In this episode, Jonathan Sackier is joined by David Crosby, Head of Prevention and Early Detection Research at Cancer Research UK. The pair discuss Crosby’s career, providing insights into Cancer Research UK’s mission, and his role within the organisation. Further discussion points include the challenges and solutions for prevention and early detection of cancer.
On this week’s episode, Evgenia, editor of the EMJ family of journals, recalls the most noteworthy moments of the last 3 months on the EMJ podcasts. Looking back on the past quarter, this episode highlights the most memorable moments with our guests, covering a range of topics, from food allergies to poetry.
In this episode, host Jonathan Sackier is joined by Rebecca Dobson, Consultant Cardiologist at Liverpool Heart & Chest Hospital, UK. The pair discuss Dobson’s career in cardio-oncology, and gender inequality in the field of cardiology. Discussion points include her experience as a female cardiologist, and her role as lead of the British Cardiovascular Society Women in Cardiology.
Development of The Greenest Inhaler podcast was supported and reviewed by Trudell Medical International.
This EMJ podcast explores the carbon footprint of different inhaler devices and features the expert insight of guest speakers Omar S. Usmani, Professor of Respiratory Medicine, Imperial College London, UK, and Consultant Physician, Royal Brompton Hospital and St Mary’s Hospital, London, UK; and John N. Pritchard, Private Consultant and Member of United Nations (UN) Committee on Propellant Medical Usage.
In this episode, Jonathan is joined by Joubert Gama, a Medical Consultant in the pharmaceutical industry. They discuss their experiences in medical school which they attended together, and Gama provides insights as to what attracted him to working in the pharmaceutical industry with an emphasis on drug development, pharmacodynamics, and clinical affairs including medical regulations and compliance. Gama takes us on a journey of what it takes to bring a drug to market, as well as delving into his surprising appearances on well-known several television series!
In this episode, Jonathan is joined by Sir Michael Brady, Professor of Oncological Imaging at the University of Oxford, UK. They discuss Brady’s educational history at Manchester and later in Australia, where he studied mathematics; how he chanced upon image analysis; and the heart-breaking story that led to Brady to start developing technology to support and inform clinicians in cancer. Brady also looks forward, discussing the future implications that artificial intelligence and robotics could have on medicine and surgery.
Our latest podcast features Robert Dellavalle, Professor of Dermatology, Colorado School of Medicine, Professor of Public Health at the Colorado School of Public Health, and physician at the University of Colorado Hospital, all based in Aurora, Colorado, USA. Dellavalle and our host, Jonathan Sackier, discuss all things dermatology, from different skin conditions to community outreach programmes and the rise of telemedicine.
Our latest podcast features Robert Dellavalle, Professor of Dermatology, Colorado School of Medicine, Professor of Public Health at the Colorado School of Public Health, and physician at the University of Colorado Hospital, all based in Aurora, Colorado, USA. Dellavalle and our host, Jonathan Sackier, discuss all things dermatology, from different skin conditions to community outreach programmes and the rise of telemedicine.
This EMJ Podcast, hosted by Gemma Boak, research scientist and health advocate, explores how psychology can be used to optimise the management of treatment for women with psoriasis. Boak is joined by Rob Horne, Professor of Behavioural Medicine and Director of the Centre for Behavioural Medicine, University College London (UCL) School of Pharmacy, UK, who shares expertise from his research, focusing on the role of psychological and behavioural factors in explaining variations in treatment responses.
Delving into some of the challenges that physicians face in the clinic, this podcast addresses women with psoriasis who hold strong doubts about their need for treatment, challenges around discussing family planning with patients, and pruritis as a life-quality limiting factor. The podcast ends by questioning listeners: what can dermatologists do to optimise the management of women with psoriasis?
This educational podcast has been funded by UCB, in which the position and discussions might not necessarily represent the position of UCB.
This EMJ Podcast, hosted by Gemma Boak, research scientist and health advocate, explores how psychology can be used to optimise the management of treatment for women with psoriasis. Boak is joined by Rob Horne, Professor of Behavioural Medicine and Director of the Centre for Behavioural Medicine, University College London (UCL) School of Pharmacy, UK, who shares expertise from his research, focusing on the role of psychological and behavioural factors in explaining variations in treatment responses.
Delving into some of the challenges that physicians face in the clinic, this podcast addresses women with psoriasis who hold strong doubts about their need for treatment, challenges around discussing family planning with patients, and pruritis as a life-quality limiting factor. The podcast ends by questioning listeners: what can dermatologists do to optimise the management of women with psoriasis?
This educational podcast has been funded by UCB, in which the position and discussions might not necessarily represent the position of UCB.
This week, Jonathan is joined by Fred T. Lee Jr., Professor of Radiology, Biomedical Engineering, and Urology at the University of Wisconsin–Madison, USA. The pair discuss Lee’s career path into the field of radiology, while detailing aspects of his father, the reputed radiologist Fred Lee’s, career. Lee emphasises the importance of different types of treatment in cancer due to the disease’s resilience and discusses revolutionary treatment techniques, including tumour ablation, histotripsy, and how he believes robots will play a role in future treatments.
This week, Jonathan is joined by Fred T. Lee Jr., Professor of Radiology, Biomedical Engineering, and Urology at the University of Wisconsin–Madison, USA. The pair discuss Lee’s career path into the field of radiology, while detailing aspects of his father, the reputed radiologist Fred Lee’s, career. Lee emphasises the importance of different types of treatment in cancer due to the disease’s resilience and discusses revolutionary treatment techniques, including tumour ablation, histotripsy, and how he believes robots will play a role in future treatments.
This podcast has been funded by a Pfizer educational grant, in which the position and discussions might not represent the position of Pfizer.
In this EMJ Podcast, our host Sue Saville is joined by Margareth Ozelo, Associate Professor of the Internal Medicine Department and Director of the Haematology Division, University of Campinas, São Paulo, Brazil, and Radek Kaczmarek, Postdoctoral Research Associate, Gene and Cell Therapy Group, Indiana University School of Medicine, Department of Pediatrics, Indianapolis, Indiana, USA, who speak about the latest developments in gene therapy for haemophilia.
This week Jonathan is joined by Hugo Davila, board-certified urologist and Clinical Assistant Professor at Florida State University, College of Medicine, Florida, USA. The pair discussed the latest innovations in the field of urology, including the use of robotics. Pertinent topics included little-discussed pathologies such as female pelvic organ prolapses and Peyronie's disease.
This week, Smeeta Sinha, Consultant Nephrologist at the Salford Royal Hospital, Manchester, UK and Visiting Professor at Manchester Metropolitan University, UK, joins Jonathan to explore renal healthcare. In this episode, the pair discuss Prof Sinha’s fascinating career, including her role in the research of calciphylaxis treatment and management. A range of pertinent topics are discussed, including the importance of patient awareness of diabetic kidney disease, and how simple innovative strategies can have a hugely positive impact on patients.
In this week’s episode, Jonathan Sackier, surgeon, innovator, and entrepreneur, explores the history and uses of regenerative medicine while highlighting its different to transplantation. Comparing the protein P53 to Kim Kardashian, Jonathan contemplates the uses of other proteins as well as the different types of regenerative medicine, including gene therapies and the use of petroleum-based prosthetics. He even provides hints to his latest project in the field and elaborates on the use of scaffolding in regenerative medicine.
This content has been funded by Novartis, the position and discussions might not represent the position of Novartis. The content was intended for non-USA and non-UK healthcare professionals.
This EMG Health podcast kicks off with Bridget Scott introducing two experts, David Ilson, Medical Oncologist, Memorial Sloan Kettering Cancer Center, Gastrointestinal Oncology, New York, USA, and Samuel Klempner, Associate Professor, Massachusetts General Hospital, Harvard Medical School, USA, who discuss critical unmet needs in the management of patients with oesophageal cancer.
This week, Peter Arkwright, Senior Lecturer in Paediatric Allergy and Immunology, Lydia Becker Institute of Immunology and Inflammation, University of Manchester, UK, and Consultant for the Department of Paediatric Allergy and Immunology, Manchester University Foundation NHS Trust, UK, joins our Editor, Evgenia Koutsouki, to speak about the prevalence of allergy and the challenges surrounding immune disease in children. In this episode, the pair discuss Dr Arkwright’s fascinating career, including the defining moment of his practice so far. A range of pertinent topics are discussed, including insights into the treatment of novel and life-threatening immune diseases, and the reasons behind the surge in infectious diseases that the world has recently observed.
The Aimee Drew Trust
This podcast was funded by a medical educational grant from AstraZeneca, with the purpose of enhancing the fundamental understanding of oncology specialists of the value of a multidisciplinary team approach in the management of patients with cancer.
In this EMJ Podcast, our host Brigitte Scott is joined by experts David Baldwin, Honorary Professor, School of Medicine, University of Nottingham, UK, Michelle Greenwood, Uro-oncology Clinical Nurse Specialist and Lead Teenage and Young Adult Nurse, St. Bartholomew’s Health NHS Trust, London, UK; and Kerry Archer, Cancer Specialist Physiotherapist, Active Against Cancer, Harrogate & District NHS Foundation Trust, UK, who share their perspectives on the multidisciplinary team (MDT)–patient dynamic and the importance of patient empowerment in multidisciplinary cancer care.
This fascinating podcast delves into alternative treatment for non-melanoma skin cancer using Rhenium-SCT; a painless, non-invasive, single-session therapy. Our host is joined by two experts in the nuclear medicine field who work together with dermatologists in the treatment of non-melanoma skin cancer (NMSC) patients: Joe Cardaci, Diagnostic Nuclear Imaging, Hollywood Private Hospital, Nedlands, Australia, and Siddhartha Baxi, Radiation Oncologist and Regional Medical Director, GenesisCare Gold Coast, Tugun, Australia.
This week, Adam Fox, Consultant Paediatric Allergist at Guy's and St Thomas' Hospitals, London, UK and Chair of the UK National Allergy Strategy Group joined our Editor, Evgenia Koutsouki, to talk all things allergy. In this episode, the pair discuss Dr Fox’s career path, which led him to setting up a specialised allergy clinic. A range of pertinent topics are discussed, including the effect of a cleaner lifestyle on our susceptibility to allergies, the evolution of food allergy, and a fascinating insight into the initial concerns surrounding COVID-19 vaccine rollout.
Jonathan hosts his old friend and former colleague, Keith Hopcroft, who now works as a general practitioner (GP) in Essex, UK. Together, they discuss the role of the GP in the modern world, and changes to continuity of care. The pair also analyse the many myths surrounding male health, and the benefits and pitfalls of using artificial intelligence in medicine.
This EMJ podcast explores the vital topic of low-density lipoprotein cholesterol (LDL-C) management in relation to the treatment and prevention of atherosclerotic cardiovascular disease. Our host, George Cooper, is joined by Michal Vrablík, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Vrablík provides a basic overview of LDL-C, how it might lead to atherosclerotic cardiovascular disease, and how this can ultimately cause a myocardial infarction. Vrablík covers current treatments for patients with high LDL-C, including statins, ezetimibe, and monoclonal antibodies that inhibit proprotein convertase subtilisin/kexin Type 9.
Disclaimer: This independent medical education activity is provided by EMJ, and was supported by independent funding from Novartis Pharma AG, who have had no input into the content. This educational activity is intended for an audience of non-US healthcare professionals. These materials may include data/information on investigational uses of compounds/drugs that have not yet been approved by regulatory authorities.
This week, Jonathan spoke with Uwe Gudat, Chief Medical Officer, Aretaeus sàrl, Geneva, Switzerland. Together, they discussed a wide range of topics, encompassing non-compliance in patients with Type 2 diabetes, patient education, and biosimilars. The pair explored statistical literacy for healthcare professionals and evidence-based medicine.
Please check out these links for further information on the topics discussed:
https://www.aretaeus.ch/
https://www.drugsafetymedicine.com/
This podcast explores with guest speaker Dr Richard Dilon the potential prognostic value of measurable residual disease (MRD) determination in the treatment and risk assessment of patients with acute myeloid leukaemia (AML).
This podcast is supported by Jazz Pharmaceuticals, who have had input into the topic and final editorial review. The views expressed in this podcast are those of the individual speakers and do not necessarily reflect the views of Jazz Pharmaceuticals.
This podcast focuses on the latest evidence supporting the use of ultrasound in diagnosis within rheumatology with a special focus on rheumatoid arthritis. The speakers consider the evidence for the use of ultrasound to diagnose rheumatoid arthritis and provide perspectives on the challenges stemming from the lack of images and how ultrasound might address them. Sackier and Moller delve into the potential impact of ultrasound on the timing of diagnosis and treatment, and whether it is more effective at ruling out a diagnosis of rheumatoid arthritis than standard methods.
This week, Jonathan spoke with David Hildick-Smith, Professor of Cardiology and Consultant Cardiologist at the Sussex Cardiac Centre, Brighton and Sussex University Hospitals, UK. The pair discussed all things cardiology, with a key focus on interventional procedures and even took a look into David’s creative past. Pertinent topics discussed include the link between migraines and patent foramen ovale and the surge in adverse cardiac events in young athletes, for which David provides his expert perspective.
Join Evgenia Koutsouki, editor of the EMJ family of journals, for this special episode of the EMG-Health Podcast as she looks back at some of the most interesting and memorable moments from the last three months. Jumping into the notable conversation that we have had, this episode provides key insights from this quarter as well as some exciting news of our own!
This week, we discuss highlights from the International Liver Transplant Society (ILTS) Annual Meeting 2022 in Istanbul, as well as insights into the managment of patients after HBV-related liver transplantation
Jonathan Sackier hosts Dr Bryan Buckley, who works in the Department of Radiology at the Mater Misericordiae University Hospital, Dublin, Ireland. Together, they explore the impact of radiology departments on the climate. Buckley analyses the vast amounts of energy necessary in radiology departments, the storage of data and the associated carbon footprint, and the impact of single-use disposable equipment across the healthcare sector.
This week, Jonathan is joined by Hugh Selsick, Consultant in Sleep Medicine and Psychiatry at University College London Hospitals, UK. Selsick delves into what led him to his role as a sleep medicine consultant in London all the way from South Africa, as well as unpacking sleep disorders that are often misdiagnosed. Jonathan also discusses Selsick’s recent work on the use of cognitive behavioural therapy as a treatment for parasomnias, and the reasons behind the negative effects of the pandemic on sleeping habits.
This week, Jonathan’s guest is Leslie Moffat, a prominent and now retired Urologist. Moffat discusses how he got into the field of urology and also reveals the reasons as to why he retired when he was 62. Delving into the history of patient transportation in war, Moffat reminisces about his time in Kyiv, Ukraine, and the people that he met there. He further discusses how males with family members who have had breast cancer could be at a higher risk of getting prostate cancer.
This week, Jonathan is joined by James Kim, Clinical Assistant Professor, Department of Family Medicine, University of Calgary, Canada. Kim talks about his time studying and working in different continents and the differences in healthcare that struck him during these experiences. Jonathan and Kim also discuss the treatment of chronic migraine using botox and how this compares with the traditional prescription of painkillers, as well as the link between climate change and chronic disease.
This week, Jonathan is joined by Sharon Allen, Co-founder and Executive Director of the World Telehealth Initiative (WTI), a non-profit organisation. Using innovative technology to connect volunteer healthcare professionals with those in need, WTI provides sustainable medical expertise to under-resourced communities around the world. They discuss how Allen came to co-found the WTI and detail the valuable work that the organisation does worldwide. Allen also touches on how COVID-19 helped develop telemedicine and how it is being used to help Ukrainian surgeons while at war. If you would like to learn more about the WTI, please check out their website at https://www.worldtelehealthinitiative.org.
Samantha Leonard, International Senior Medical Director, Natera, Texas, US, discusses prenatal screening exploring essential questions surrounding this topic, from how prenatal screening tests work to the future of genetic screening technology.
This podcast has been funded by Natera. The tests described have been developed and performance characteristics determined by the CLIA-certified laboratory performing the test. The tests have not been cleared or approved by the US Food and Drug Administration (FDA). Although FDA is exercising enforcement discretion of premarket review and other FDA legal requirements for laboratory-developed tests in the US, certification of the laboratory is required under CLIA to ensure the quality and validity of the tests. CAP accredited, ISO 13485 certified, and CLIA certified 2022 Natera, Inc. All Rights Reserved.
This EMG-Health podcast explores options for treating females with psoriasis and questions the surrounding factors that must be taken into consideration. Featuring the expert opinion of Paolo Gisondi, Associate Professor of Dermatology and Venereology, University Hospital of Verona, Italy, this podcast explores sex-specific challenges in patients with psoriasis with articular manifestations.
This week, Jonathan’s guest is Jonathan Samet, Dean of the Colorado School of Public Health, Aurora, Colorado, USA, and a Professor of Epidemiology, Environmental, and Occupational Health. In this episode, Samet discusses the impact of climate change on healthcare, particularly with regard to the links between pollutants and respiratory conditions. Samet considers how incidences of cancers and respiratory diseases will increase as a consequence of climate change, and how this could impact the practice of clinicians.
This week, Jonathan’s guest is Agnes Fogo, Professor of Pathology, Microbiology, and Immunology at the Vanderbilt School of Medicine, Nashville, Tennessee, USA. In this episode, Fogo talks about the transatlantic move from her home in Norway and the progression of her extremely successful career. Jonathan and Fogo also discuss a range of pertinent issues around the field of renal pathology, including advances in renal biopsies, Fogo’s presidency at the International Society of Nephrology (ISN), the future of medical publishing, and the shift towards online education during the COVID-19 pandemic.
In this episode, Jonathan is joined by Dr Oliver Grundmann, Clinical Professor, Department of Medicinal Chemistry, University of Florida, Gainesville, USA. They discuss how Grundmann ended up training and teaching in the USA, their opinions on the use of vitamins, and how the gut microbiota and central nervous system are connected. Grundmann also talks about his own podcast for the University of Florida: https://addictionresearch.health.ufl.edu/.
This week, Jonathan is joined by Dr Alia Medniuk, a Consultant Anaesthetist and Clinical Lead for Acute and Inpatient Pain Management at the North Bristol NHS Trust Southmead Hospital in the UK. They discuss her career and explore the reasons she chose to pursue medicine, touching on important topics like ‘the opioid crisis’, advancing to speak about individualised treatment plans and how personal experiences as a patient can influence the practice of clinicians.
This EMG-Health podcast, hosted by Brigitte Scott, explores the treatment landscape and emerging therapies in oesophageal cancer over the last decade, placing an emphasis on novel research and treatment. Scott introduces two leading experts in oesophagogastric cancer: Geoffrey Ku, Medical Oncologist, Memorial Sloan Kettering Cancer Center, New York, USA, and Peter Siersema, Director of the Endoscopy Center, Co-Director of the Radboud Technology Center, Radboud University Medical Center, Nijmegen, the Netherlands.
In this one-off special, we look back at some of the most memorable moments from the 2022 series of the EMG Health Podcast with the editor of the EMJ family of journals, Evgenia Koutsouki. As we reflect on the year so far, we delve into some of the key insights provided by our guests, as well as other notable conversations, opinions, and perspectives that have made this year’s series such a fascinating listen.
This EMG Health podcast explores the vital role that microbiology testing will play in countering the impending challenge that antimicrobial resistance (AMR) presents. Featuring expert opinions from Jean Patel and Fabienne Wichmann, this podcast highlights the emergence of AMR, potential harms AMR may engender, and the varied rates of AMR seen between regions and countries.
This EMG Health podcast explores the vital role that microbiology testing will play in countering the impending challenge that antimicrobial resistance (AMR) presents. Featuring expert opinions from Jean Patel and Fabienne Wichmann, this podcast highlights the emergence of AMR, potential harms AMR may engender, and the varied rates of AMR seen between regions and countries.
This EMG Health podcast explores the vital role that microbiology testing will play in countering the impending challenge that antimicrobial resistance (AMR) presents. Featuring expert opinions from Jean Patel and Fabienne Wichmann, this podcast highlights the emergence of AMR, potential harms AMR may engender, and the varied rates of AMR seen between regions and countries.
This week, Jonathan delves deeper into the history of battlefield medicine and how war can give rise to ground-breaking innovations, many of which have become part of routine medical practice. From exploring the origin of ambulances to discussing the birth of plastic surgery and the introduction of the modern triage system, Jonathan details the variety of scientific breakthroughs that have arisen from conflict and demonstrates that terrible circumstances can lead to revolutionary advances in medical care.
In this episode, Jonathan sits down with Paola Pasquali, established dermatologist with particular expertise in cryosurgery and non-invasive imaging, but most recently graduated a grandmother! They discuss how the COVID-19 pandemic has brought teledermatology into focus, how minimally invasive diagnostics can help to make early diagnosis of skin cancer, and how using cryosurgery is an effective method of destroying cancerous cells. Jonathan also compares his notes on some of Pasquali’s passions; cooking and photography.
In this podcast, Jonathan Sackier, host of the EMG-Health podcast, discusses important topics in men’s health with a focus on erectile dysfunction (ED). Two leading experts in the field share their perspectives, knowledge gaps in the disease area, and the impact ED can have on a patient’s well-being.
This content is funded by Viatris
This week, Jonathan focuses on the ongoing conflict in Ukraine, discussing the disastrous impacts of war, from environmental consequences to effects on healthcare systems. Via exploration of long-term mental health implications, the plethora of issues arising with housing and providing for refugees, and the direct dangers associated with warzones; Jonathan details the damage war inflicts, and outlines the efforts being made to aid those in need, as well as what good can be done in these times of crisis.
Please use the following links to engage with the charitable initiatives mentioned in this episode aiming to help in Ukraine:
UNICEF - https://www.unicef.org/ukraine/en
BritishRedCross - https://donate.redcross.org.uk/appeal/ukraine-crisis-appeal
Save the Children - https://www.savethechildren.org.uk/where-we-work/europe/ukraine
Choose Love - https://donate.chooselove.org/campaigns/ukraine-appeal/
To get in touch about the EMG Health Podcast please email editorial@emjreviews.com
This podcast is a discussion around the impact of COVID-19 on healthcare systems and patient care backlogs. Hosting the episode is Professor Gregory Lip, Price-Evans Chair, Cardiovascular Medicine, University of Liverpool, who is joined by Professor Fausto Pinto, Dean of the Faculty of Medicine, University of Lisbon. Tune in to find out the impact of COVID-19 on healthcare systems overall, but particularly on the diagnosis of arrythmia and dyslipidemia. This podcast has been sponsored Daiichi Sankyo.
CVD/22/0045 - March 2022
This podcast is an exploration of the impact of COVID-19 on the diagnosis and treatment of cardiovascular patients. Hosting is Professor Gregory Lip, Price-Evans Chair, Cardiovascular Medicine, University of Liverpool, who is joined by Professor Jose Luis Zamorano, Professor of Medicine and Head of Cardiology, Hospital Ramón y Cajal. Tune in to find out about the consequences of COVID-19 for cardiovascular patients, particularly those with arrythmia and dyslipidaemia. This podcast has been sponsored by Daiichi Sankyo.
CVD/22/0044 - March 2022
This podcast explores the latest advancements in gene therapy for the treatment of haemophilia, including what the future of gene therapy could mean for both clinicians and patients. Our guests are Steven Pipe and Laurence Woollard, who explore both sides of the debate in haemophilia the understanding of the researcher, clinician, and healthcare professional, as well as the impact this has from the patient's perspective. This podcast has been funded by a Pfizer educational grant, in which the position and discussions might not represent the position of Pfizer.
This week, Jonathan contemplates the practice of mindfulness, from its ancient Vedic roots to its contemporary popularity, and how applying this focused thinking can improve our wellbeing. Through exploring the methodology of this spiritual exercise, detailing statistics from clinical trials, and examining real-world applications, we determine the ways in which patience can benefit patients.
In this week’s bonus episode of the EMG-Health podcast, we have two experts in the field of direct oral anticoagulants for the treatment of cancer related venous thromboembolisms: F.A. (Erik) Klok and Harry Gibbs.
Klok and Gibbs discuss patient cases that they have come across in their field of work and how the new treatments and trial updates have influenced their decision making, providing their opinions and the decisions they would make in certain scenarios.
This week, Jonathan broaches a controversial topic: Do vitamins and supplements actually improve our health, or are they a waste of our money? From Vitamin A to Vitamin Z, Dr Sackier explores the perceived health benefits of supplements, why our modern diet has transcended deficiency diseases, and how improving the evidence provided by regulatory bodies could help to justify the billions of dollars that half of all Americans spend on these substances.
This week, Jonathan is joined by Mike Einziger, a multiple Grammy-nominated musician, inventor, and technology entrepreneur. They speak about Mike’s impressive career in music and interesting gravitation towards science, touching on the technology companies he has founded: Mixhalo and Versicolor Technologies. Conversations also cover the skin condition tinea versicolor, pigmentation, and other applications of Mike’s curious involvement in dermatology.
A review of the latest and most pertinent information from EULAR 2021 regarding COVID-19 for patients with rheumatic musculoskeletal diseases. This includes an overview of the topic, from an assessment of the safety profile of vaccines, to the impact of biologic or targeted synthetic disease-modifying anti-rheumatic drug treatment on COVID-19 outcomes. The discussion then shifts to a review of research presented at EULAR 2021 examining the promise demonstrated in clinical trials for small molecule JAK1 inhibitors in the treatment of patients with ankylosing spondylitis. Furthermore, the episode features an expert analysis of how drugs traditionally used to treat RA have been repurposed to battle the COVID-19 pandemic. This podcast is supported by Janssen Pharmaceutical Companies of Johnson & Johnson. The views expressed in this podcast are those of the individual speaker and do not necessarily reflect the views of Janssen Pharmaceutical Companies of Johnson & Johnson.
The novel data presented at EULAR 2021 highlights the latest treatment options and safety aspects for patients with psoriatic arthritis (PsA). Discussing the data presented by Laura Coates at EULAR 2021, the episode centres on the safety and efficacy of guselkumab treatment for patients with PsA who inadequately respond to TNF inhibitors. Other key research presented at EULAR 2021 is spotlighted, including clinical trials investigating alternative PsA treatment options such as selective allosteric TYK2 inhibitor deucravacitinib, an analysis of IL-17 inhibitor secukinumab and new insights into faecal microbiota transplantation.
This podcast is supported by Janssen Pharmaceutical Companies of Johnson & Johnson. The views expressed in this podcast are those of the individual speaker and do not necessarily reflect the views of Janssen Pharmaceutical Companies of Johnson & Johnson.
This week, Jonathan is joined by Dr Steve Wexner, Chairman of the Department of Colorectal Surgery at the Cleveland Clinic, Miami, Florida, USA. In this episode, the pair consider how the coronavirus pandemic has affected surgery, faculty meetings, and clinical education. As they outline Dr Wexner’s illustrious career, a range of pertinent topics are discussed, including ‘greener’ travel and remote healthcare, disparities in access to modern medicine and the poverty gap, the legal steps involved with safely innovating in science, and advances in minimally invasive surgery.
Experts Antoni Chan, Consultant Rheumatologist and Associate Medical Director, Royal Berkshire NHS Foundation, UK, and Laura Coates, Associate Professor, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK, discuss axial spondylarthritis and psoriatic arthritis. Delving into prevalence, associated symptoms, delays in diagnosis, and recent study findings, this podcast provides insight into these conditions. This content was funded by an educational grant from Pfizer. The views and opinions expressed are those of the speakers and not necessarily of Pfizer.
This week, Jonathan discusses the ancient spiritual practices of yoga and meditation, outlining historical and scientific evidence of how these methods can improve physical and mental wellbeing and help us to ‘stretch the stress away.’ Jonathan details the global interest in yoga, from its roots in Northern India over 5,000 years ago, right through to the spread of its popularity in the 20th Century, and how performing ‘asanas’ and ‘pranayamas’ may provide strong clinical benefits for patients with a range of conditions, on and off the mat.
The music used in this episode is taken from https://www.FesliyanStudios.com
Dr. Subarna Chakravorty and Dr. Rachel Kesse-Adu discuss their highlights from ASH surrounding sickle cell disease.
Focussing on the presentations, posters and abstracts around the current advances and future possibilities of SCD. Novel approaches for treatment and new therapies.
This podcast was funded by Novartis, the views and opinions expressed are those of the speakers and do not necessarily represent the position of Novartis. All content was generated independently of Novartis.
This podcast, led by Julie Ann Lough, an award-winning broadcaster and producer based in the UK, and Caitriona Ryan, Consultant Dermatologist, Institute of Dermatology, Blackrock Clinic and Hermitage Medical Clinic, Dublin, Ireland, delves into the question of whether patients are being failed by the healthcare system, and explores why sex matters in psoriasis management. This podcast is only for use by healthcare professionals.
This educational podcast has been fully sponsored by UCB and the content does not necessarily reflect the views of UCB.*
Prof. Ryan has received honoraria for serving on advisory boards, as a speaker, or as a consultant from AbbVie, Allergan, Aqua, Dermira, Dr Reddy’s, Janssen, Leo, Lilly, Medimetriks, Novartis, Regeneron-Sanofi, UCB, and Xenoport.
For further information on how UCB processes personal data click HERE https://www.ucb.com/Privacy-policy-for-Healthcare-Professionals
This week, Jonathan hosts Chiara De Biase, Director of Support and Influencing, Prostate Cancer UK, and Amy Rylance, Head of Improving Care, Prostate Cancer UK. They discuss the implications of the coronavirus pandemic on prostate cancer in the UK, as well as current modes of raising awareness, and emerging treatment options in the form of novel hormonal therapies.
Access the Prostate Cancer UK website here: www.prostatecanceruk.org
Use this link to complete the risk checker discussed in this episode: https://prostatecanceruk.org/risk-checker
Oral contraception is a great asset in family planning that leads to female empowerment. In this podcast three leading experts from the field of gynecology and hemostasis Kristina Gemzell Danielsson, Diana Mansour and Jonathan Douxfils discuss the brief history and development of combined oral contraceptives and talk about access to contraception during the COVID-19 pandemic. They will also have a discussion about the present situation of VTE risk and combined hormonal contraception and will present data on effect on hemostasis parameters of the estetrol 14.2 mg and drospirenone 3 mg combination. (14.2 mg estetrol as 15 mg estetrol monohydrate)
Disclaimer: The publication of this podcast was funded by Gedeon Richter. The discussion represents the opinion of the speakers and was not influenced by Gedeon Richter. The information contained in this podcast is solely for healthcare professionals and is not for an audience without the relevant education. It is not intended as, and shall not be understood or construed as, medical or health advice.
In this podcast, hosted by Julie Ann Lough, experts in oesophageal cancer come together to discuss current treatments, and offer valuable insights into the future of the field. This follows from the European Society of Medical Oncology (ESMO) satellite session titled ‘Navigating the Current Treatment Landscape in Oesophageal Cancer with an Eye Toward the Future’, which took place in September 2021.
Lough is joined by three specialist oncologists: Elizabeth Smyth, a Consultant in Gastrointestinal Oncology, Addenbrooke’s Hospital, Cambridge, UK; Jean-Phillippe Metges, an Oncologist at the University Hospital of Brest, France; and Lucjan Wyrwicz, a Professor and Head of the Department of Oncology and Radiotherapy, Maria Sklodowska-Curie National Cancer Research Institute, Warsaw, Poland.
This week, Jonathan is joined by Jeffrey Ponsky, Professor of Surgery, the Cleveland Clinic, USA. They review Jeff’s career with reference to advances in flexible endoscopy and the rise of medical devices, also discussing innovative approaches to surgery, and the evolution of medical training. The pair finish by evaluating modern medicine and the high cost of drugs.
Review of the Janssen-Sponsored Virtual Satellite Symposium titled “Targeting IL-12/23 in ulcerative colitis: from evidence to bedside”, which took place at the UEG Week Virtual 2021 congress. This review covers the highlights from the presentations, providing a vital insight into the current landscape of ulcerative colitis.
Disclaimer: Sponsored by Janssen Pharmaceutical Companies of Johnson & Johnson in EMEA, Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium
Jonathan sits down for a discussion with Dr Rola Hallam, Founder, CanDo, former Medical Director, Hand in Hand for Syria, and human rights campaigner. Together, they assess the harrowing issues of health disparity across the globe, Rola’s experiences providing aid in Syria, and what we all must do to aid the humanitarian crisis.
This podcast is an exploration of the journey from publication to practice of The Selecting Therapeutic Targets in Inflammatory Bowel Disease initiative, otherwise known as STRIDE II. Hear from three experts in the field of IBD as they explore the creation of treat-to-target guidelines, discuss the different consideration for monitoring in Crohn’s disease and ulcerative colitis, and reveal how to implement treat-to-target guidelines in patient care. This podcast has been sponsored by Abbvie.
This week, Jonathan speaks with David Jayne, Professor of Surgery, University of Leeds. They discuss global citizenship with the aim of gaining international experience and advancing clinical practice, as well as intuitive robotic surgery, and exploring the ‘comic opera’ of surgical research, all amidst intermittent snoring from David’s dog.
This week, Jonathan continues his series on alternative medicine by escorting us to South America to learn about the hallucinogenic brew, ayahuasca. He explores the science behind its benefits and risks, takes us through a typical ayahuasca ceremony, and contemplates the weight of leaving your life in the hands of a shaman.
This podcast reviews presentations at EULAR focusing on the emerging role of X-ray, ultrasound, and MRI in the management of PsA in the clinical setting. The presentation by Mikkel Østergaard, University of Copenhagen, Denmark, on the current imaging modalities used in PsA is discussed, with particular emphasis placed on the benefits and pitfalls of each technology.
Discussing presentations from experts Georg Schett, Freidrich-Alexander University, Erlangen-Nürnberg, Germany; Stefan Siebert, University of Glasgow, UK; and Christopher Griffiths, University of Manchester, UK, the first podcast reviews evidence exploring the potential of the IL-23 pathway in PsA. The discussions highlight both the role of the IL-23 pathway in the pathogenesis of PsA and the potential IL-23 inhibitors hold for improving PsA outcomes.
This week, Jonathan takes us through his thoughts on 2021’s landmark achievements and follies in the healthcare space, including an overview on COVID-19, improvements in women's’ health, and new innovations that rocked the boat, all topped off with his own wishes for the improvement of healthcare.
A review of the Janssen-Sponsored Virtual Satellite Symposium titled “The dermatologist’s guide to the clearance of the skin”, which took place at the recent EADV 2021 conference.
This review will provide a vital insight into current strategies for the management of psoriasis and psoriatic arthritis.
Hosting this episode is Professor Brian Kirby from St. Vincent's University Hospital in Dublin, Ireland, who’s joined by Professor Melinda Gooderham from the SKiN Centre for Dermatology in Peterborough, Ontario, Canada.
Disclaimer
This podcast is supported by Janssen Pharmaceutical Companies of Johnson & Johnson. The views expressed in this podcast are those of the individual speaker and do not necessarily reflect the views of Janssen Pharmaceutical Companies of Johnson & Johnson
Hosting this podcast episode is Professor Matthias Augustin from the Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Centre Hamburg-Eppendorf, Germany, and Professor Ulrich Mrowietz from the Department of Dermatology, University Medical Centre Schleswig-Holstein, Campus Kiel, Germany, who together during this Janssen-sponsored podcast will share with you their highlights of EADV 2021.
This week, Jonathan speaks with Bruce Gingles, Founder, Business, Entrepreneurship, Science & Technology (BEST). Bruce shares his perspective on how the medicinal system has shifted and continues to do so, delving into discussions around economics, bureaucracy, and the evolving role of physicians. He also tells the tale of his run in with a headless snake.
This week, Jonathan continues his series on alternative medicine by taking us back in time to the roots of medicine through herbal remedies, the benefits and risks of turning to earthly salves, and why a dose of healthy scepticism is always good for the soul.
This week, Jonathan speaks with Andy Sleet, Managing Partner, OYF Ltd, who tells the story of how his career was turned on its head, steering him into business coaching. He also illuminates the importance of business skills for clinicians, as well as detailing his close work with a particular charity, Kids Inspire.
This week, Jonathan speaks with Chip Helm, Author, and National Sales Manager, Cook Medical. They ruminate over leadership, personal branding, and how to sell yourself, all with a good helping of humility. Chip also offers insights and wisdom from the two books he’s authored, as well as a sneak peak into his upcoming publication.
This week, Jonathan speaks with Kris Aves, Metropolitan police officer, about the day of the Westminster Bridge attack in March 2017, the implication that Kris’ injuries have had on his life, and how sports teams can better empower communities of people living with disabilities.
In this weeks bonus episode of the EMG-Health podcast, we have to experts in the field of Direct Oral Anticoagulants for the treatment of cancer-related venous thromboembolisms. Dr. Marc Carrier (Ottawa, Canada) and Dr. Harry Gibbs (Melbourne, Australia).
This week, Jonathan sits down with Dr Fasiha Kanwal, Professor of Medicine, Chief of Gastroenterology and Hepatology, Baylor College of Medicine. They explore her work towards fighting non-alcoholic steatohepatitis (NASH), underline the importance of changing lifestyles to combat fatty liver disease, and ponder over the recent rise of pseudoscience.
This week, Jonathan speaks with Professor Kenneth Stahl. They look at the similarities between doctors and pilots, explore Professor Stahl’s time working in trauma management within the Kurdish army, discuss what they think makes an 'expert', while also touching on gun laws in the US.
This week, Jonathan is joined by Michael Blackhurst, Founding Director, JTJ Services. They explore the value of a sabbatical year and self-reflection, voyage through the metaverse and the rise of NFTs in healthcare, and detail what informed innovation truly means.
| Mycosis fungoides (MF) and Sézary syndrome (SS) are rare cutaneous T-cell lymphomas (CTCL). With a current lack of accessible treatments and insufficient patient support, affected patients are faced with an array of unmet needs, which may have a significant impact on their quality of life. In this podcast discussion, Richard Cowan, an oncologist with The Christie NHS Foundation Trust, Manchester, UK, and expert on CTCL, provides insights into both MF and SS. |
This week, Jonathan continues his series on alternative medicine by serenading us with the science of music therapy, exploring its use in pain management, stress relief, and overall health and wellbeing.
This episode, sponsored by AstraZeneca, is on the topic of ovarian cancer. Hear from two experts in the field, Professor Frederik Marmé and Professor Christina Fotopoulou, as they discuss the impact of late diagnosis and delayed treatment on patient outcomes, risk reduction strategies, and HRD testing.
This week, Jonathan tucks into the contentious topic of diets. On his plate is the impact of overconsumption, how diet can interact with the microbiome, and his views on intolerances and milk alternatives.
In this podcast, sponsored by Thermo Fisher Scientific, discover the latest in antimicrobial resistance (AMR), specifically the long-term impact of antibiotic overuse in sepsis. Hear from expert, Evangelos Giamarellos-Bourboulis, Professor of Internal Medicine and Director of the Master Programme in Infectious Diseases at ATTIKON University Hospital, Athens, Greece, who will discuss the PROGRESS trial, which compared procalcitonin-guided therapy to standard care, finding significant mortality benefit of biomarker-guided antibiotic therapy.
This week, Jonathan talks to Dr Giles Bond-Smith, Emergency General, Hepato-Pancreatico-Biliary Surgeon, Oxford University Hospitals NHS Trust. Together, they compare the UK and US medical systems, explore alternatives to outdated processes within the NHS, and Dr Bond-Smith details his work around surgical sites of infection (SSI) reduction strategies.
This week, Jonathan journeys through anecdotes to make an appeal to his fellow healthcare workers. He urges his colleagues to use their voice and take on more responsibility in encouraging COVID-19 vaccine uptake and prevention, one patient at a time.
This week, Jonathan sits down with Dr Malaz Boustani as he shares his experience of migrating from Syria to the US, explores brain health and preservation, and discusses how he copes with his own fear of death.
This week, Jonathan is joined by Dr Chris Streather, Group Chief Medical Officer, Deputy CEO, London’s Royal Free Hospital. They explore the potential of integrated care systems, offer their professional and personal perspectives on what makes a great leader, and Dr Streather shares his personal story of recently becoming a patient after suffering from a stroke.
This week, Jonathan kicks off a new series on alternative medicine by investigating the ancient practice of acupuncture. He walks us through the history, theory, and uses of the therapy, linking the concepts of traditional and conventional medicine.
This week, Jonathan is discussing ticks and Lyme’s disease, explaining the history, causes, diagnosis, and prognosis of the condition. He also explores other various kinds of ticks, as well as the diseases and syndromes they can cause, and provides advice on what to do if you do get bitten.
In this podcast, sponsored by Thermo Fisher Scientific, discover the continuing advantages of chromosomal microarray in cytogenetics. Jonathan sits down with Dr Shashi Shetty, Director of Cytogenetics Laboratory, Cleveland Medical Centre, Cleveland, Ohio, to explore at what point microarrays are the preferred choice for genetic research testing in the age of next generation sequencing (NGS). They will also explore the multiple factors that can influence the choice to implement microarrays in a research testing regime.
This week, Jonathan talks with husband and wife team, Awwad Awwad and Constance Campion. They navigate the nuances of aesthetic surgery, explore what a holistic and patient-centric approach truly means, discuss the partnership of doctor and nurse, and share their experiences of integrating work and married life.
This week’s episode is a follow-up from a previous episode published back in February called ‘Into the Flow: AKI Prevention with RenalGuard’, which centered around RenalGuard and the ability to prevent Acute Kidney Injury (AKI) through its use in percutaneous interventions. For part two, we are exploring the use of RenalGuard in cardiac surgery and how implementing this device translates to improved patient outcomes and management. Joining the podcast this time is Dr Heyman Luckraz, Cardiothoracic Surgeon, American Hospital, Dubai, United Arab Emirates, who has studied the use of RenalGuard to reduce AKI in cardiac surgery patients in a randomized controlled trial. The incidence of cardiac surgery associated AKI is around 30%, and Dr Luckraz will be discussing the findings of ICU and hospital stays, touching on long-term renal follow-up, and quality of life amongst other topics. This podcast is supported by a grant from KANEKA Medical.
This week, Jonathan talks with Carolee Lee, CEO and Founder, WHAM!, CEO and Founder, AccessCircles. They consider how a lack of investment in women’s health can impact the economy, uncover gender research disparities, and delve into her experience of setting up multiple enterprises and non-profits.
This week, Jonathan sits down with Professor Wendy Tindale, OBE, Director of Innovation, Sheffield Teaching Hospitals, NHS Foundation Trust. They delve into the world of innovation, considering what ‘value’ means, the benefits and burdens of working within the NHS, and discuss the national differences within innovation. Professor Tindale also shares her experience of being awarded an OBE.
This week, Jonathan contends with the Cotswold Way, discussing the bucolic bliss of the trail as he reminds us of the health advantages of walking; including the benefits for our immune system, weight control, sleep cycle, and mental health.
This week, Jonathan sits down with Dr Larry Diamond, Clinical Pharmacist, Anticoagulation Services, Michigan Medicine. They discuss the role of pharmacists on hospital wards, explore microbial stewardship, consider the evidence behind aspirin as a prevention tool, and bask in their shared love of aviation.
This week, Jonathan sits down with Professor Leigh Charvet, Director of Multiple Sclerosis Research, NYU Grossman School of Medicine. They explore her vast research within MS, consider her time working in industry compared with her experiences in academia, and evaluate the impact of mindfulness when used in conjunction with traditional treatments.
This podcast, supported by an educational grant from Eli Lilly, explores the latest developments in RET-driven thyroid cancer that were presented at the American Society of Clinical Oncology’s (ASCO) 2021 virtual conference. Hear from two experts, Dr Nicola Normanno and Dr Jonathan Wadsley, as they discuss the latest efficacy and safety data in patients with RET-driven thyroid cancer, RET testing, and the future of RET-driven diseases.
This podcast, supported by an educational grant from Eli Lilly, explores the latest developments in RET‑driven lung cancer that were presented at the American Society of Clinical Oncology’s (ASCO) 2021 virtual conference. Hear from two experts, Dr Maximilian Hochmair and Dr Fernando Lopez-Rios, as they discuss the importance of the RET gene, the latest safety and efficacy information, the role of testing, and future predictions within this landscape.
This week, Jonathan sits down with Dr Michael Peck, Anaesthesiologist, and Chief Medical Officer, AirMid Critical Care Products. They consider the important relationship between surgeon, anaesthesiologist, and patient, discuss Michael's time working and studying abroad, and explore life lessons he has learnt from practising karate.
This week, Jonathan sits down with Professor John Markowitz, Professor of Clinical Psychiatry, and Research Psychiatrist at New York State Psychiatric Institute. They untangle and investigate different forms of therapy, explore his research into depression, PTSD, and trauma, and discuss the influence the pandemic has had on our mental health.
This week, Jonathan is discussing the topic of survival. Inspired by the book 'The Disappearing Spoon' by Sam Kean, he reveals a dramatic and very personal tale of survival, involving a song, the periodic table, and the trunk of a car.
This week, Jonathan sits down with Professor Babak Kateb, Chairman and CEO, Society for Brain Mapping and Therapeutics, to reflect on his upbringing and experience of war and how that influenced his career, discuss the potential of cross-discipline collaboration, and reveal what he thinks will be the spaces to watch in neurology and research.
This episode, sponsored by Novartis, features Dr Adriano Venditti, Associate Professor, Haematology, University of Rome Tor Vergata and Dr Lars Bullinger, Department of Haematology, Oncology and Tumour Immunology, Charité University Medicine. Together, they discuss the treatment of patients who have acute myelogenous leukemia (AML) as well as FMS-like tyrosine kinase 3 gene (FLT3) mutations.
Jonathan sits down with Prof Carl Hauser, Visiting Professor of Surgery and Lecturer on Trauma, Beth Israel Deaconess Medical Center and Harvard Medical School, to discuss what makes a good physician, explore his research around the mitochondria, and delve into his career as guitarist in the New York-based band, The Druids of Stonehenge.
This episode, sponsored by an educational grant from Sanofi Genzyme and Regeneron, is the final instalment in a five-part series exploring the subject of atopic dermatitis (AD). Hear from Dr Stephan Weidinger, Professor of Dermatogenetics, Christian-Albrechts-University, Germany, who discusses advancements in the treatment of moderate-to-severe AD, including the nuances of treatment options, long-term strategies, and how the disease affects people's everyday lives.
This week, Jonathan sits down with three leaders from the charity accelerator The Voluntary Solidarity Fund (VSF) to discuss the complex topic of marginalisation. Jean Pierre Casey, Executive Trustee, VSF, Andy Keen-Downs, CEO, Prison Advice and Care Trust (PACT), and Caroline Hattersley, Director, women@thewell, all reveal the intrinsic relationship between health and social inclusion, unravelling how good health is far more intricate than freedom from disease.
This episode, sponsored by an educational grant from Amarin Corporation, is a discussion around primary prevention and treatment of atherosclerotic cardiovascular disease (ASCVD). Professor Alberico Catapano, Professor of Pharmacology, The University of Milano, Italy, discusses practical considerations that address all aspects of a patient’s lifestyle habits and estimated risk of a future ASCVD event, which is critical prior to deciding on the need for pharmacotherapy.
This week, Jonathan muses on the importance of emerging from the pandemic safely, addressing conspiracy theories, vaccine hesitancy, public uncertainty, and the role of strong leadership, all through an analogy of aviation.
Jonathan sits down with Dr Shailesh Vadodaria, Consultant Aesthetic Plastic Surgeon, MACS Clinic, London, to discuss the rising cases of gynecomastia, reflect on his missionary and charity projects, and explore spirituality and synchrodestiny.
This week, Jonathan sits down with Eugene Lipov, Chief Medical Officer, Stella Center, to explore the subject of mental health. They discuss how our collective understanding of trauma is maturing, explore Lipov's work in the fields of Stellate Ganglion Block (SGB) treatment and the Lipov Block Procedure, and reflect on his experience co-authoring a children’s book with his son.
This episode, sponsored by Novartis, is a discussion around myelodysplastic syndrome (MDS). Dr Esther Natalie Oliva, Great Metropolitan Hospital BMM, Italy, and Dr David Valcárcel, Vall d'Hebron University Hospital, Spain, elucidate on data regarding immunotherapy for the treatment of patients living with MDS from the recent European School of Haematology (ESH) 7th Translational Research Conference.
This week, Jonathan sits down with Dr Caroline Michie, Consultant Medical Oncologist, Honorary Clinical Senior Lecturer, Edinburgh Cancer Centre & University of Edinburgh to discuss the challenges of cancer care during and post-pandemic, as well as regional differences in healthcare.
This episode, sponsored by medac, is a discussion around non-muscle-invasive bladder cancer (NMIBC). We hear from Professor Jørgen Bjerggaard Jensen, who leads clinical research in bladder cancer at the Department of Urology, Aarhus University Hospital, as he explores the management of NMIBC through the neoadjuvant use of Mitomycin C (MMC).
This episode, sponsored by an educational grant from Sanofi Genzyme and Regeneron, is the fourth instalment in a five-part series exploring the subject of atopic dermatitis (AD). Hear from Dr Chih-Ho Hong, Dermatologist, and Dr Peter Lio, Clinical Assistant Professor, Northwestern University, Feinberg School of Medicine, who explore the roles of dupilumab versus emerging Janus kinase (JAK) inhibitor therapies in children, adolescents, and adults with moderate-to-severe AD.
This week, Jonathan reflects on the boom of the well-being industry, considering what it gets right, highlighting where it goes wrong, and offers tips on how to spot themes of pseudoscience.
This week, Jonathan sits down with Russ Bradford and Charlotte Allen, Founders, Parkinson’s Concierge, to discuss their personal experiences with the disease, the work they do to raise awareness of it, and how they feel healthcare systems could better support people living with Parkinson's.
This episode, sponsored by Novartis, features Dr Yishai Ofran, Department of Haematology and Bone Marrow Transplantation, Rambam Medical Center, Haifa, Israel, and Dr Maria Garcia-Fortes, Hospital Universitario Virgen de la Victoria, Málaga, Spain. Together, they discuss developments and data presented at the American Society of Haematology (ASH) 2020 virtual conference regarding the management of patients with acute myeloid leukaemia (AML).
This week, Jonathan sits down with Joe Capraro, Partner in the Patent and Intellectual Property Groups at Proskauer Rose LLP to decipher the elements of a patent, decode the process of protection, and decide how to choose the best lawyer.
This week, Jonathan sits down with Mark Adickes, Orthopaedic Surgeon and former NFL player. Together, they reflect on his transition from professional sport to sports medicine, consider what makes a good doctor, and explore both the mental and physical dangers of sport-related injuries.
This episode, sponsored by an educational grant from Sanofi Genzyme and Regeneron, is the third instalment in a five-part series exploring the subject of atopic dermatitis (AD). Hear from Dr Maria Angles, Paediatric Dermatologist, Hospital Italiano of Buenos Aires, who shares the treatment results in early and sustained improvements in adolescents and adults with moderate-to-severe AD.
This week, Jonathan reflects on the ongoing efforts of students and retired healthcare professionals joining the NHS during the COVID-19 pandemic, and considers the difficult decisions that can accompany this move.
Jonathan sits down with Meryvn Singer, Professor of Intensive Care Medicine, UCL, to discuss the role of intensive care in the pandemic and beyond, consider what physicians have learnt over the past 12 months, and reveal why innovation has peaked during COVID-19.
This week, Jonathan sits down with Dr Brian Dunkin, Chief Medical Officer, Boston Scientific, to explore the advancements in minimally invasive surgery, reflect on the growth of telemedicine, as well as consider the science behind recruitment and embedding culture within organisations.
This week, Jonathan talks to Dr Brannon Claytor, Plastic Surgeon, Claytor Noone Plastic Surgery, Philadelphia, about the rise in male patients requesting procedures, his experience delivering mission surgery in Bangladesh, as well as the surprising correlations between plastic surgery and aviation.
This episode, sponsored by an educational grant from Sanofi Genzyme and Regeneron, is the second instalment in a five-part series exploring the subject of atopic dermatitis (AD). Hear from Dr Mette Deleuran, Chair, Department of Dermatology, Aarhus University Hospital and Dr Peck Ong, Associate Professor, Clinical Paediatrics, Keck School of Medicine, University of South Carolina, discussing the disease burden and quality of life of patients with AD.
Jonathan reflects on the principles, origins, and history of medical ethics, exploring the moral complexities and real world risks of not upholding the integrity of these principles.
Jonathan sits down with Dr Robert Waldman, Addiction Expert, Cliffside Malibu Treatment Center (LA) to explore our shifting attitudes towards addiction, consider the theory of ‘gateway drugs’, and assess why addiction and substance abuse has been on the rise during lockdown.
This episode, sponsored by KANEKA, provides a scientific update on the incidences, risks, and effects of Acute Kidney Injury (AKI) in interventional and other procedures as well as covering prevention strategies and exploring how state-of-the-art RenalGuard diuresis forced matched hydration meets all critical prevention requirements.
Jonathan sits down with Mark Barone, Vice President, International Diabetes Foundation, for a discussion about his personal experience with diabetes, how the medical professional can encourage healthier lifestyle choices, and how we can tackle health inequities in diabetes and beyond.
This episode, funded by a grant from Sanofi, is the first of a five-part series exploring dermatology and the subject of atopic dermatitis (AD). Hear from Dr Miriam Wittmann, Associate Professor, Inflammatory Skin Diseases, The University of Leeds, who focuses on the COVID-19 pandemic and its impact on AD research.
This week, Jonathan talks to Richard Jenkins, Chief Medical Officer, Emirates, to discuss innovation in healthcare, the impact of COVID-19 on the aviation sector, and how to safeguard the physical and mental health of pilots and cabin crew as they face the greatest challenge to commercial aviation in recent history.
This week, Jonathan reflects on the issue of the men’s health gap, exploring the data behind the disparity, why a health gap exists, and how to engage with male patients to improve diagnosis rates and disease outcomes in the future.
Jonathan sits down with Professor Mark Lawler, Associate Pro-Vice-Chancellor and Professor of Digital Health, Queen’s University Belfast, to explore working closely with communities, tailoring approaches for different populations, recruiting celebrities for awareness campaigns, and the impact of COVID-19 on oncology.
This episode, funded by a grant from Philips, explores physiology as a guidance tool to improve the practice and outcomes of coronary intervention with Dr Rasha Al-Lamee, Interventional Cardiology Consultant, Imperial College NHS Trust and Nick Curzen, Professor of Interventional Cardiology, University of Southampton.
This week, Jonathan is joined by Norvell ‘Van’ Coots, President and CEO, Holy Cross Health. Together, they reflect on his start in dermatology, his service in the US military, and the promising rise of telemedicine in bringing patient care closer to home and into the community.
Jonathan sits down with James Carroll, CEO and Founder, THOR Photomedicine, to explore the innovative world of photobiomodulation. They explore the clinical applications of laser therapy, discuss James's journey into entrepreneurship, and consider what the future of healthcare might look like.
Jonathan sits down with Professor Michael Barnes, Chief Medical Officer, Lyphe Group and Director, Maple Tree Consultancy, to explore the subject of medicinal cannabis. They investigate the challenges in overcoming bureaucracy, the importance of educating healthcare professionals about its potential, as well as his work campaigning for cannabis to be prescribed on the NHS.
This episode, sponsored by Veracyte, is an overview of the European Breast Cancer Congress symposium ‘The Pathway to the Future of Breast Cancer Care’, featuring Bonnie Anderson, Chairman, CEO, Veracyte and Giulia Kennedy, Chief Scientific Officer, Chief Medical Officer, Veracyte, discussing the challenges and rewards of developing useful biomarker assays using machine learning and artificial intelligence.
In the final episode of 2020, Jonathan takes a moment to consider how much the healthcare landscape has changed in light of COVID-19, for the worse and for the better, as well as highlighting some of the fantastic leaps that have been made in innovation and discovery over the period.
This week, Jonathan is joined by Ganapathy Krishnan, Founder and President, Apollo Telemedicine Networking Foundation. Together, they explore why India is the perfect case study for telemedicine, the importance of garnering support for telehealth from governments and policymakers, as well as his future outlook for aviation and space medicine.
This week, Jonathan is joined by Jeremy Stone, Healthcare Entrepreneur, Innovator, and Physician. Together, they discuss his reputation as a business angel, his passion for aeronautics, his transition away from academia, and the importance of entrepreneurship and investing in start-ups when kick-starting innovation in healthcare.
This episode, sponsored by Janssen, is an overview of the UEG Week Virtual 2020 symposium ‘Dynamic management of CD: reaching a new dimension in patient care’, highlighting the latest developments in Crohn’s disease management.
This week, Jonathan is joined by Deirdre Kelly, Paediatric Hepatologist and Chair of the ESPGHAN Public Affairs Committee. They reflect on her upbringing in India, debate the pros and cons of the NHS, and discuss her work with children facing liver transplantations, as well as how best to provide patients with a sense of autonomy over their conditions.
This episode, sponsored by Vifor pharma, provides an overview of the current challenges in achieving remission for patients with ANCA associated vasculitis, assessing the consequences and regularity of relapse, its association with longer-term damage or clinical outcomes, and how patients view relapse.
This week, Jonathan sits down with Professor Sumanth Gandra, Assistant Professor, Washington University School of Medicine, to discuss antimicrobial resistance in India. They investigate AMR disparity in high and low-income countries, the need for improved education amongst healthcare professionals, and the role of mass gatherings and the food industry in deepening the problem.
This week, Jonathan chats to Simon Shepard, CEO, Optima-life and Chartered Physiotherapist, about how to sustain both mental and physical strength, best practice for managing patient expectations, and his time as an medical adviser for television shows.
This week, Jonathan explores the history and evolution of the FDA, taking a look at the key milestones, starting from the first medieval food regulations to the institution's response to COVID-19.
This week, Jonathan chats to Mike Bewick, Founder and Director of iQ4U Consultants, to discuss the subject of innovation. They explore incredible advancements in oncology and patient technology, the impact of Brexit on healthcare, and consider what doctors can learn from nurses.
Jonathan chats to Professor Sabiha Essack, Research Chair in Antibiotic Resistance and One Health, University of KwaZulu-Natal. They discuss gaps highlighted by the pandemic, the over-prescribing of antibiotics, and the link between antimicrobial resistance and COVID-19.
This week, Jonathan chats to Yulun Wang, Fellow, Teladoc Health and Founder of InTouch Health, about telemedicine. They explore the potential of robotics, the pros and cons of virtual care, and consider how the fourth industrial revolution is transforming the healthcare industry.
This week, Jonathan reflects on the importance of Continuous Medical Education for healthcare professionals. As new drugs are developed and changing methods of practice are pioneered and innovated, we consider the channels through which doctors can stay up to date on the latest developments to ensure they are always serving patients with the best possible care.
Jonathan sits down with Steve Westaby, Cardiac Surgeon, Author, and Pioneer of Circulatory Support Technology, to discuss innovation. They reflect on his extensive career in heart surgery, touching on the humanity of patient care, amusing anecdotes from medical school, and sobering stories from the operating theatre.