Clinical Gastroenterology & Hepatology: Recent Episodes
AGA
An engaging mix of author interviews and expert commentary on the latest articles from Clinical Gastroenterology and Hepatology, hosted by the AGA journals' online editor, John F. Kuemmerle, MD, AGAF.
A study in the March 2015 issue of CGH finds that withdrawal of immunomodulators after at least 6 months of co-treatment with infliximab does not reduce the trough levels of infliximab in patients with Crohn's disease.
An article in the February issue of CGH looks at solutions to issues concerning fecal microbiota transplantation, and challenges involving this increasingly common procedure that still remain. Dr. Kuemmerle speaks with author Dr. Alexander Khoruts.
An article in the January issue of CGH investigated the incidence, etiology, and outcome of GI bleeding in patients with ventricular assist devices. Dr. Kuemmerle speaks to co-author Dr. John Vargo of the Cleveland Clinic.
A study in the November issue of CGH investigated whether increasing doses of mesalamine reduces concentrations of fecal calprotectin in patients with quiescent ulcerative colitis. Dr. Kuemmerle speaks to author Dr. James D. Lewis.
An AGA Board Strategic Update article in the October issue of CGH discusses recent changes to how a gastroenterologist demonstrates value in the era of the Affordable Care Act. Dr. Kuemmerle speaks to Dr. Lawrence Kosinski.
An article and accompanying editorial in the September issue of CGH discuss reinitiating infliximab therapy for inflammatory bowel disease patients after a period of discontinuation. Dr. Kuemmerle speaks w/ editorial co-author Dr. Maria T. Abreu.
An editorial in the August issue of CGH discusses changing treatment methods for Hepatitis C Virus infection over the last several years. Dr. Kuemmerle speaks to first author Dr. Fasiha Kanwal of Baylor College of Medicine.
An article in the July issue of CGH looks at management of dyslipidemia as a cardiovascular risk factor in patients with nonalcoholic fatty liver disease (NAFLD). Dr. Kuemmerle speaks to Dr. Kathleen Corey
A commentary in the June issue of CGH looks at the effect of proton pump inhibitors (PPIs) and nonsteroidal anti-inflammatory drugs (NSAIDs) on the lower gastrointestinal tract. Dr. Kuemmerle speaks to author Dr. Francis KL Chan.
A review article in the May issue of CGH looks at the major advances in risk assessment, molecular genetics, DNA mutational analyses, and cancer prevention and management of Lynch syndrome over the last 100 years; with guest Dr. Fay Kastrinos
Eosinophilic esophagitis (EoE) has become a major cause of upper gastrointestinal morbidity in children and adults. A study in the April issue of CGH estimates the prevalence of EoE in the United States. Dr. Kuemmerle speaks to author Dr. Evan S. Dellon
An “Advances in Translational Science” article in the March issue of CGH looks at the future of DNA testing and molecular screening for colon cancer. Dr. Kuemmerle speaks with author Dr. John M. Carethers of the University of Michigan Dept of Medicine
An article in the February issue of CGH offers a primer for gastroenterologists on the use of new anticoagulant and antiplatelet agents. Dr. Kuemmerle speaks with author Dr. Geoffrey M. Forbes
A phase 2 study in the January 2014 issue of CGH investigated the efficacy of allogeneic mesenchymal stromal cells in patients with luminal Crohn's disease. Dr. Kuemmerle speaks with author Dr. Geoffrey M. Forbes
A study in the December CGH finds that constipation and a low-fiber diet are not associated with diverticulosis. A related "Perspectives in Clinical Gastroenterology and Hepatology" article reconsiders conventional wisdom about diverticular disease.
A review in the November issue of CGH provides a practical guide to evaluation and management of pregnant patients with abnormal liver chemistries or function. Dr. Kuemmerle speaks to Dr. Mary E. Rinella
Two related articles appear in the October issue of CGH: "Methods for Diagnosis of Bile Acid Malabsorption in Clinical Practice” and “Bowel Functions, Fecal Unconjugated Primary and Secondary Bile Acids, and Colonic Transit in Patients With IBS.”
An article in the September issue of CGH summarizes the pathophysiology of hemostasis in liver disease, describes pros and cons of lab tests for those patients, and outlines the optimal management of hemostasis for various clinical scenarios.
An article in the August CGH discusses the dangers and advantages physicians should consider when utilizing the internet and social media in their medical practices or private communications. Dr. Kuemmerle speaks to Dr. Andrew D. Feld.
A study in the July issue of CGH compares the colonic microbiome and volatile organic compound metabolome of obese nonalcoholic fatty liver disease patients with that of healthy-weight individuals. Dr. Kuemmerle speaks to author Dr. Kevin P. Rioux.
A study in the June issue of CGH looks at whether a test-based or empiric dose-escalation strategy is more cost-effective for treating Crohn's disease patients who have stopped responding to Infliximab. Dr. Kuemmerle speaks to Dr. Fernando S. Velayos.
Two articles in the May issue of CGH look examine side effects and complications of long-term proton pump inhibitor use, and fundoplication for GERD treatment. Dr. Kuemmerle discusses the pros and cons of each approach with the authors of these articles.
An editorial in the April issue of CGH takes a new look at the risks and benefits of thiopurines in treating Crohn's disease. Dr. Kuemmerle speaks to Dr. Stephen B. Hanauer of the University of Chicago Medical Center
A study in the March issue of CGH evaluated 31 pregnant women with IBD who receive Anti-TNF agents to determine transfer rates of the drugs to the fetus via the placenta. Dr. Kuemmerle speaks to Dr. Uma Mahadevan.
A study in the February issue of CGH evaluated the prevalence of adenomas detected by sex, age, race/ethnicity, and colon location in a large population. Implications of these findings for screening and quality programs are discussed.
An “Advances in Translational Science” article in the February issue of CGH looks at promises, delivery, and challenges of IBD risk gene discovery. Dr. Kuemmerle speaks with Dr. Steven Brant
Two studies in the December issue of CGH report potentital positive findings in treatment of obscure gastrointestinal bleeding. Dr. Kuemmerle speaks to the author of an accompanying editorial, Dr. Shajan Peter.
An article in the November issue of CGH provides guidance to GI practitioners who are transitioning to electronic health records. Dr. Kuemmerle speaks to author Dr. Michael L. Weinstein.
An article in the October issue of CGH reviews the latest approach to diagnosis of eosinophilic esophagitis (EoE) and presents consensus diagnostic guidelines. Dr. Kuemmerle speaks to author Dr. Evan S. Dellon.
A “Perspectives in Clinical Gastroenterology and Hepatology” article in the September issue of CGH provides condition-specific rationale for using probiotic therapy and literature-based recommendations. Dr. Kuemmerle speaks to author Dr. Matthew A. Ciorba
In patients with hepatitis c virus infection and early-stage fibrosis, increased levels of alanine aminotransferase was found to correlate with liver stiffness among patients in the lowest strata of fibrosis. Dr. Kuemmerle speaks with Dr. Nezam Afdhal.
As CGH welcomes a new Board of Editors in the July 2012 issue, Dr. Kuemmerle speaks to Dr. John I. Allen, new section editor of Practice Management: The Road Ahead, in a special, wide-ranging interview about the future of GI practice.
A meta-analysis of population-based cohort studies to determine the risk of colorectal cancer in patients with ulcerative colitis appears in the June issue of CGH. Dr. Kuemmerle speaks to author Dr. Tine Jess.
Telbivudine reduces hepatitis B virus (HBV) DNA and normalizes levels of alanine aminotransferase (ALT) in patients with chronic hepatitis B (CHB). A study in the May issue of CGH by Dr. Calvin Pan investigates its use in preventing vertical transmission.
A study in the April issue of CGH examines determinants of serum alpha fetoprotein (AFP) levels in hepatitis C–infected patients. Dr. Kuemmerle speaks to author Dr. Hashem B. El-Serag.
A study in the March issue of CGH looks at whether primary sclerosing cholangitis is also a risk factor for colorectal dysplasia or cancer in patients with Crohn's disease of the colon. Dr. Kuemmerle speaks with senior author Dr. Roger Chapman
A Practice Management article in the January 2012 issue of CGH outlines three major options for owners of ambulatory surgery centers (ASCs) to deal with decreased reimbursements and rising costs. Dr. Kuemmerle speaks with author Dr. Lawrence R. Kosinski
Adverse Events Do Not Outweigh Benefits of Combination Therapy for Crohn's Disease in a Decision Analytic Model. Dr. Kuemmerle speaks to the first author of this study in the January issue of CGH, Dr. Corey Siegel.
A “Perspective” article in the December issue of CGH looks at the rationale, methods, and use of fecal microbiota transplantation as treatment for Clostridium difficile infection. Dr. Kuemmerle speaks to co-author Dr. Christina Surawicz.
A look at new information in the November issue of CGH concerning Transjugular Intrahepatic Portosystemic Shunts (TIPS) for complications of cirrhosis. Dr. Kuemmerle speaks to Dr. Arun Sanyal of Virginia Commonwealth University
Upper abdominal pain in patients with gallstones is often treated by cholecystectomy but frequently persists. A study in the October issue of CGH found factors that determine patients' odds for relief. Dr. Kummerle speaks to author Dr. Johnson L. Thistle
A review article in the September issue of CGH looks at the pathogenesis of infections and immune dysfunction in patients with cirrhosis. Dr. Kuemmerle speaks to author K. Rajender Reddy of the University of Pennsylvania Health System
Early Fluid Resuscitation Reduces Morbidity Among Patients With Acute Pancreatitis; Lactated Ringer's Solution Reduces Systemic Inflammation Compared With Saline in Patients With Acute Pancreatitis. Dr. Kuemmerle interviews author Dr. Timothy B. Gardner
A study in the July CGH looked to diagnose the primary biliary cirrhosis (PBC)–chronic autoimmune hepatitis (AIH) overlap syndrome and their level of overlap at a tertiary referral center. Dr. Kuemmerle speaks with Dr. Marshall M. Kaplan.
Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis, according to a study in the June CGH. Dr. Kuemmerle speaks to the author of an accompanying editorial, Dr. David T. Rubin
A Perspective article in the May issue of CGH examines the challenges of monitoring patients with Crohn's disease who remain symptomatic despite anti–tumor necrosis factor therapy. Dr. Kuemmerle speaks to author Dr. William Sandborn
An “Education Practice” article in the April issue of CGH looks at a clinical scenario involving evaluation and treatment of noncardiac chest pain. Dr. Kuemmerle speaks with author Dr. David Katzka.
A study in the March issue of CGH identifies renal dysfunction as the primary independent predictor of mortality in cirrhotic patients with spontaneous bacterial peritonitis (SBP). Dr. Kuemmerle speaks to study author Dr. Guadalupe Garcia–Tsao
An Education Practice article in the February issue of CGH looks at a clinical scenario involving evaluation and removal of diminutive polyps found during colonoscopy
A study in the December issue of CGH sought to clarify the importance of histologic analysis of biopsy samples in the diagnosis and management of patients with autoimmune hepatitis (AIH). Dr. Kuemmerle speaks to study co-author Dr. Keith Lindor
A review in the December issue of CGH examines the causes of liver disease among the HIV-infected population in the era of antiretroviral therapy (ART). Dr. Kuemmerle speaks to author Dr. Jennifer Price.
A prospective study in the November issue of CGH evaluates the safety and efficacy of Enterra therapy in patients with chronic intractable nausea and vomiting from diabetic gastroparesis. Dr. Kuemmerle speaks to author Dr. Richard McCallum.
A study in the October 2010 CGH examines safety and complications of percutaneous liver biopsy in patients with hepatitis C–related bridging fibrosis or cirrhosis who were enrolled in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial.
A Clinical Practice article in the September issue of CGH looks at a scenario of a 41-Year-Old woman with complaints of intermittent nonbloody diarrhea, abdominal cramping, and bloating.
Dr. Kuemmerle speaks with Dr. Bruce Bacon about a new set of quality indicators for treatment of patients with cirrhosis. Also, a new segment highlighting stories from the AGA newspaper, GI & Hepatology News
An editorial in the July issue of CGH summarizes current information and questions about anti–tumor necrosis factor therapy in Crohn's disease. Dr. Kuemmerle speaks to author Dr. Charles N. Bernstein of the University of Manitoba.
Traveler's Diarrhea is the most common illness among travelers. A paper in the June issue of CGH offers tips for travelers to prevent and treat the disease.
Two clinical scenarios in the “Education Practice” section of May's CGH look at approaches to acute pancreatitis during stages of early management and follow-up, respectively. Dr. Kuemmerle speaks with author Dr. Bechien U. Wu.
A review in the April issue of CGH summarizes the available evidence regarding colonoscopy and radiographic studies in the management of acute lower intestinal bleeding. Dr. Kuemmerle speaks to author Dr. Lisa Strate.
An editorial in the March issue of CGH discusses how physicians can best address the cancer risk of Barret's Esophagus with patients. Dr. Kuemmerle speaks with the author, Dr. Nicholas Shaheen of the University of North Carolina at Chapel Hill.
Do symptom-based, Rome criteria for IBS lead to better diagnosis and treatment outcomes? Dr. Kuemmerle speaks to two authors of articles in the February 2010 CGH that offer pro and con perspectives.
A study in the January 2010 CGH investigates diseases and drugs that present possible risk factors for acute large bowel ischemia (ALBI).
Dr. Kuemmerle speaks with Dr. Stuart J. Spechler of the Dallas VA Medical Center, author of an editorial looking at surgical treatment for gastroesophageal reflux disease (GERD) in the December issue of CGH
A retroactive study of double balloon endoscopy complications at nine US centers appears in the November 2009 issue of CGH.
A study in the October 2009 CGH looks at presentation and management of post-treatment relapse in autoimmune pancreatitis (AIP) and immunoglobulin G4–associated cholangitis.
Dr. Ronnie Fass discusses the effect of nighttime symptoms of gastroesophageal reflux disease (GERD) on sleep quality and outcomes. This study appears in the September issue of CGH.
Dr. Bruce Sands looks at the rate of non-Hodgkin's lymphoma in adult Crohn's disease patients who have received anti-TNF therapy, compared with that of a population-based registry and a populationof CD patients treated with immunomodulators.
Dr. George Triadafilopoulos discusses his special report in the July issue of CGH on use of proton pump inhibitors for clinical management of gastroduodenal damage related to NSAIDs or aspirin.
Dr. Charles Kahi speaks about his study in the July CGH on the impact of screening colonoscopy on the incidence and mortality of colorectal cancer.
Dr. Kuemmerle speaks with Dr. Adeyinka Laiyemo, author of a study in the May issue of CGH that follows up on the utilization and yield of surveillance colonoscopy among participants in the Polyp Prevention Trial (PPT).
Dr. Kuemmerle speaks with Dr. Ganesh Veerappan, co-author of a study in the April CGH that looks at prevalence and clinical predictors of eosinophilic esophagitis (EoE) in patients undergoing elective upper endoscopy.
Dr. Kuemmerle speaks with Dr. Robert P. Myers, who looked at mortality rates and frequency of surgery in patients admitted on weekends for peptic ulcer–related hemorrhage, and Dr. Ashwin N. Ananthakrishnan, who analyzed weekend patients ...