HIV/AIDS and Infectious Disease: Recent Episodes

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Guest: Paul Hunter, MD
The Advisory Committee on Immunization Practices (ACIP) recently updated their recommendations for the 2024-2025 flu season. Here to give us a breakdown of the key updates so we can protect our patients from the flu is family medicine physician Dr. Paul Hunter.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA
Guest: Jill Foster, MD
Guest: John Russell, MD
According to recent studies, co-administering the flu, RSV, and COVID-19 vaccines is generally safe, which is why both the CDC and Advisory Committee on Immunization Practices support this approach. However, there are some important considerations to keep in mind when co-administering these three respiratory vaccines, which is why Dr. Mary Katherine Cheeley speaks with Drs. Jill Foster and John Russell about best practices for co-administration and improving vaccination rates. Dr. Foster is the Director of the Division of Pediatric Infectious Diseases at the University of Minnesota Medical School, and Dr. Russell is a family medicine physician at Jefferson Health System in Abington, Pennsylvania.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: John Russell, MD
According to the CDC, flu vaccine coverage for all adults is about 47 percent, and there’s been a continued decline among pregnant patients and children since 2020. These reduced vaccination rates can have serious consequences for our patients and the healthcare system as a whole, which is why it’s so important for primary care providers to embrace their role in reversing this trend. To help in this mission, Dr. Charles Turck speaks with family medicine physician Dr. John Russell about strategies for boosting flu vaccination rates in the primary care setting.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Darvin Scott Smith, MD
Vaccines play a crucial role in preventing the flu itself, but there are a lot of lesser-known benefits of flu vaccination as well, including its impact on reducing illness severity, hospitalization rates, and co-infections as well as its importance in managing chronic diseases and enhancing public health outcomes. Joining Dr. Charles Turck to examine the comprehensive advantages of flu vaccination is Dr. Darvin Scott Smith, who’s an infectious disease consultant at San Mateo Medical Center in California.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Laila Woc-Colburn, MD, DTM&H, FACP, FIDSA
Since annual flu shots help alleviate the severe disease burden on patients and the healthcare system as a whole, it’s important to make flu vaccination a part of every patient visit. Fortunately, tools like appointment reminders, in-office discussions, and infographics can help us integrate this preventative measure into routine patient care and protect them from the flu. To learn more about these strategies, Dr. Charles Turck speaks with Dr. Laila Woc-Colburn, Associate Professor at the Emory University School of Medicine in Atlanta.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Norman Beatty, MD
Guest: Marvin J. Bittner, MD
Pretravel consultation is essential for a lot of patients with upcoming travel plans so that we can anticipate and mitigate any risks they may encounter. Each conversation is unique to the health aspects of the patient's travel plans. To dive in for best practices when preparing patients for international travel, join Dr. Charles Turck as he speaks with expert panelists, Dr. Norman Beatty, Assistant Professor of Medicine at the University of Florida College of Medicine in the Division of Infectious Diseases and Global Medicine, and Dr. Marvin Bittner, Interim Program Director of the Infectious Diseases Fellowship Program and Special Professor in the Department of Medicine at Creighton University in Omaha, Nebraska.

Valneva did not contribute to the educational content.

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Host: Jennifer Caudle, DO
Guest: Michael Barnish, DO
Guest: Norman J. Bizon, PA-C, CTH
Before traveling abroad, it’s important that patients schedule a pre-travel health consultation with their doctor to go over their itinerary and talk about potential risks at their destination. There certainly are patients who are more at risk, such as those with immune-compromising conditions. To learn how to best collaborate with your patients before they travel internationally, dive in with Dr. Jennifer Caudle as she speaks with expert panelists, Dr. Michael Barnish, Infectious Disease Specialist at Rowan Medicine, and Mr. Norman Bizon, Physician Assistant who focuses exclusively on travel medicine at Travel Bug Health.

Valneva did not contribute to the educational content.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: David Hamer, MD
Cases of dengue have more than doubled since 2023, especially in endemic areas like Latin America, the Caribbean, South and Southeast Asia, and the coastal areas of Africa. This increasingly prevalence underscores the importance of knowing how to protect patients traveling abroad to those areas, which is why Dr. Charles Turck speaks with Dr. David Hamer about essential prevention strategies for dengue fever. Dr. Hamer is a Professor of Global Health and Medicine at the Boston University School of Public Health.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: David Hamer, MD
Cases of chikungunya have risen significantly in recent years, but fortunately, there are several ways we can protect our patients traveling abroad, including with a novel vaccine and other anti-mosquito measures. Joining Dr. Charles Tuck to discuss key preventive strategies for the chikungunya virus is Dr. David Hamer, Professor of Global Health and Medicine at the Boston University School of Public Health.

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Host: Robert Walker, PharmD
Guest: Nic Garner, PharmD
Travel vaccines are becoming increasingly common as they play a key role in protecting travelers abroad, but they’re only effective if patients actually receive them. That’s why Dr. Robert Walker speaks with Dr. Nic Garner, who shares best practices for counseling patients on travel vaccines. Dr. Garner is the District Support Pharmacist Leader at CVS Pharmacy in Texas with more than 10 years of community pharmacy management experience.

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Host: Jody Takemoto, PhD
Guest: Robert Wong, MD
Hepatitis B is one of the leading causes of liver cancer globally, underscoring the importance of screening, diagnosing, and treating patients appropriately. However, there are several considerations to keep in mind when caring for patients with hepatocellular carcinoma with hepatitis B co-infection, which is why Dr. Jody Takemoto speaks with Dr. Robert Wong about those factors and essential management strategies. Dr. Wong is a Clinical Associate Professor of Medicine in the Division of Gastroenterology and Hepatology at Stanford University School of Medicine.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Christina Madison, BS, PharmD, BCACP, AAHIVP
The World Health Organization and the Vaccines and Related Biologics Products Advisory Committee recently recommended transitioning from quadrivalent to trivalent flu vaccines that exclude the B/Yamagata lineage. Explore the epidemiological data that led to this decision and counseling strategies that can help patients understand this new recommendation with Dr. Charles Turck and Dr. Christina Madison, founder and CEO of the Public Health Pharmacist.

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Guest: Darvin Scott Smith, MD
For optimal protection, the most prevalent flu strains are assessed every year and included in the vaccine. Here to talk about this process and the recent decision to exclude the B/Yamagata lineage from flu vaccines is Dr. Darvin Scott Smith, Infectious Disease and Geographic Medicine Consultant at San Mateo Medical Center in California.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Jill Foster, MD
For optimal protection, the best time for patients to receive a flu shot is between September and October, but some patients may be hesitant. In fact, flu vaccination rates have been declining since the onset of the COVID-19 pandemic according to the CDC. That’s why Dr. Charles Turck speaks with Dr. Jill Foster about how we can help ensure patients receive timely and annual flu vaccinations. Dr. Foster is the Director of the Division of Pediatric Infectious Diseases at the University of Minnesota Medical School in Minneapolis.

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Host: Matt Birnholz, MD
Guest: Donald Kohn, MD
Third-generation lentiviral vectors were developed to improve upon safety measures and mitigate the risks of toxicity and replication that are typically associated with first- and second-generation therapies. These advancements may help enhance the functionality and utility of third-generation lentiviral vectors in various gene therapy applications. Learn more about the development, efficacy, and safety of third-generation lentiviral vectors with Dr. Matt Birnholz and Dr. Donald Kohn, Distinguished Professor at the University of California, Los Angeles.

This non-certified educational series is produced and controlled by ReachMD, and is intended for healthcare professionals only.

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Host: Charles Flexner, MD
Daily oral therapy can have low adherence, which is why the field of long-acting formulations is rapidly advancing. Tune in to hear Dr. Charles Flexner discuss how long-acting regimens can address this problem of adherence and help patients living with HIV, tuberculosis, malaria, and other infectious diseases. Dr. Flexner is a Professor of Medicine of Pharmacology, Molecular Sciences, and International Health at Johns Hopkins University, and he also presented a session on this exact topic at the 2024 Conference on Retroviruses and Opportunistic Infections.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Emerging data over the years has shown the role of GLP-1 receptor agonists, not only in terms of their initial role in managing diabetes and blood sugar but also the secondary benefit of sometimes massive amounts of weight loss. However, there hasn’t been a tremendous number of studies looking at the use of these agents in patients with HIV. Join Dr. Charles Turck as he dives into the data further with Dr. Darcy Wooten, Clinical Professor of Medicine and a Program Director for the University of California San Diego ID Fellowship Training Program in the Division of Infectious Diseases and Global Public Health.

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Host: Jeffrey Kwong, DNP, MPH
Managing co-occurring conditions in patients with HIV can be challenging. But by taking certain steps—like updating management guidelines, screening for complications, and implementing prevention strategies—we can overcome those challenges and improve the way we care for HIV patients with co-occurring conditions. Here to discuss those strategies is Dr. Jeffrey Kwong, a Professor in the Division of Advanced Nursing Practice at Rutgers University School of Nursing. He also spoke about this exact topic at the 2023 Annual ANAC conference in his session, titled “Managing Co-Occurring Conditions: A Clinical Update.”

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: William R. Short, MD, MPH, AAHIVS
As of January 2023, the breastfeeding guidelines for HIV patients were updated, and they now recommend supporting the parent’s choice through shared decision-making. Joining Dr. Charles Turck to share what these new guidelines look like in practice and key counseling strategies for HIV patients is Dr. William Short. Dr. Short is an Associate Professor of Medicine and Infectious Disease at the University of Pennsylvania in Philadelphia, and he also spoke about this exact topic at the 2023 ANAC conference in his session, titled “New Recommendations for Infant Feeding for Persons with HIV in the United States.”

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Host: Rachel Denyer, MD
About one in every three people living with HIV has a positive hepatitis B core antibody. But how frequently does hepatitis B reactivation occur after a patient with HIV switches to an antiretroviral regimen that has no hepatitis B activity? Find out with Dr. Rachel Denyer as she shares key data she presented at IDWeek 2023 in the session titled “Hepatitis B Reactivation in Persons with HIV with Positive Hepatitis B Core Antibody After Switching to Antiretroviral Therapy Without Hepatitis B Activity.”

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Stuart M. Levitz, MD
Treating fungal infections can be difficult due to the limited treatment options available, but could antifungal vaccines help change that? To catch us up on the progress being made in immunotherapeutic and vaccine strategies, Dr. Charles Turck speaks with Dr. Stuart Levitz about the “Antifungal Vaccines: Where Are We At?” session he presented at IDWeek 2023.

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Host: Jeffrey Freiberg, MD, PhD
The field of infectious diseases is always evolving thanks to new research studies, data, and treatment options. To help us catch up on some of these essential updates, Dr. Jeffrey Freiberg is here to give us an overview of the “What's Hot in ID in Clinical Science” session he helped develop for IDWeek 2023.

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Guest: Natalia Castillo Almeida, MD
感染流感会增加住院和罹患严重疾病的风险,尤其对高风险患者而言。幸运的是,接种流感疫苗可以帮助个人有效应对此类情况。在本节目中,内布拉斯加州大学医学院传染病系助理教授 Natalia Castillo Almeida 医生分享了关于住院率的关键数据和流感疫苗的接种建议。

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: John J. Russell, MD

Guest: Darvin Scott Smith, MD

Hospitals and health systems face several economic and logistical challenges due to low rates of flu vaccination. Fortunately, there are policies, programs, and initiatives that can be implemented in health system environments and at the community level to increase flu vaccination rates. Learn more with Drs. Darvin Scott Smith and John Russell. Dr. Smith is an Infectious Disease Consultant of Public Health Works, LLC in Northern California, and Dr. Russell is a family medicine physician at Jefferson Health System in Abington, Pennsylvania.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Keith C. Ferdinand, MD, FACC, FAHA, FASPC, FNLA

Vaccines are essential in reducing death and disability related to influenza, but unfortunately, not all patients have equal access to these life-saving resources. In fact, many barriers exist, like misinformation and lack of public awareness and education. That’s why Dr. Charles Turck speaks with Dr. Keith Ferdinand about ways we can break down barriers and improve vaccination rates among members of racial and ethnic minority communities.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA

Guest: Valeria Cantos Lucio, MD

HIV diagnoses in the United States have declined two-thirds since the start of the pandemic in the 1980s. However, the Latino community are still facing high risk of infections. To learn more on providing better access to care for these patients, join Dr. Mary Katherine Cheeley as she speaks with Dr. Valeria Cantos Lucio, Associate Professor of Medicine in the Department of Infectious Diseases at Emory University and an investigator at the Ponce de Leon research site.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Darvin Scott Smith, MD

There are several benefits associated with using real-world evidence to assess vaccine effectiveness, especially in the context of flu vaccines. Find out why and what the real-world evidence says about the effectiveness of flu vaccines with Dr. Charles Turck and Dr. Darvin Scott Smith. Dr. Smith is an infectious disease consultant of Public Health Works, LLC in Northern California.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Jill Foster, MD

The clinical and economic burden associated with the flu is particularly heavy for our youngest patients. Learn more about this burden and how influenza vaccines can help reduce it with Dr. Charles Turck and Dr. Jill Foster, Professor in the Department of Pediatrics and the Director of the Division of Pediatric Infectious Diseases at the University of Minnesota Medical School in Minneapolis.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA

Guest: Dylan Baker, MD

Georgia has the highest rate of new HIV diagnoses out of any state in the country, and so it’s imperative that we make this medication more accessible now in order to save future generations from living with HIV. To dive further into the benefits and challenges of this program, Dr. Mary Katherine Cheeley is joined by Dr. Dylan Baker, Assistant Professor of Medicine at Emory University and the Associate Medical Director of the Grady PrEP Clinic.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Sorana Segal-Maurer, MD

Research has shown that those living with HIV are more likely to be malnourished and experience nutrient deficiencies that play an essential role in their immunity. In the early days of HIV, a typical recommendation was to increase a patient’s calorie count. To discuss how the focus on nutrition has changed now that this patient population is living much longer, Dr. Charles Turck is joined by Dr. Sorana Segal-Maurer, Director of Infectious Diseases at New York-Presbyterian Queens and Professor of Clinical Medicine at Weill Cornell Medicine in New York City.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Sorana Segal-Maurer, MD

For most patients living with HIV, antiretroviral therapy is extremely effective. However, HIV mutates with frequency, allowing it to become resistant to antiviral medication. To discuss how we can effectively treat these patients, Dr. Charles Turck is joined by Dr. Sorana Segal-Maurer, Director of Infectious Diseases at New York-Presbyterian Queens and Professor of Clinical Medicine at Weill Cornell Medicine in New York City.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA

Guest: Steve Grinspoon, MD

The risk of cardiovascular disease is twice as great among patients living with HIV, and this could partly be due to traditional risk factors, along with nontraditional risk factors. Here to discuss the results from the REPRIEVE study with Dr. Mary Katherine Cheeley is Dr. Steve Grinspoon, Co-Principal Investigator and Professor of Medicine at Harvard Medical School in Boston.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA

Guest: Sarah Bauerle Bass, PhD, MPH, FSBM

Although the rate of new HIV diagnoses in the United States is steadily declining, people in prisons are still disproportionately living with the virus, which is why researchers at Temple University are now developing an app aimed at improving HIV prevention and substance use treatment access for incarcerated women in Philadelphia. To learn more about this research, Dr. Mary Katherine Cheeley is joined by Dr. Sarah Bauerle Bass, Associate Professor of Social and Behavioral Sciences and the Director of Risk Communication Laboratory at Temple University.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Kamel Khalili, PhD

Scientists at Temple University’s Lewis Katz School of Medicine have identified a novel gene-editing strategy aimed at eliminating HIV-1 infection with no adverse effects on cell mortality. Find out how this recent discovery could get us one step closer to a cure for HIV with Dr. Charles Turck and Dr. Kamel Khalili, the Laura H. Carnell Professor in the Department of Neuroscience and Chair of the Department of Microbiology, Immunology & Inflammation.

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Host: Ryan Maves, MD

Guest: Megan Conroy, MD, MA(Ed)

Respiratory syncytial virus (RSV) is most commonly recognized for the significant disease it causes in infants and young children. However, over time its prevalence in adults has increased. Tune in to learn more with Dr. Ryan Maves as he speaks with Dr. Megan Conroy, Assistant Professor of Medicine at the Ohio State University in Columbus.

This program is produced in partnership with the American College of CHEST Physicians and is supported by an educational grant from GSK.

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Host: Ryan Maves, MD

Guest: Kelly Pennington, MD

It’s estimated that respiratory syncytial virus (RSV) is responsible for up to 30 percent of viral respiratory infections in the stem cell transplant population. So how can we help RSV patients achieve their best outcomes? Learn more with Dr. Ryan Maves as he speaks with Dr. Kelly Pennington, Assistant Professor of Medicine at the Mayo Clinic in Rochester, Minnesota.

This program is produced in partnership with the American College of CHEST Physicians and is supported by an educational grant from GSK.

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Host: Jerome Lisk, MD

Guest: Santosh Kumar, PhD

In an effort to examine the correlation between HIV-induced aging and Alzheimer’s disease in the United States population, a team of researchers at the University of Tennessee Health Science Center are working to develop a novel drug delivery system. To learn more, Dr. Jerome Lisk is joined by Dr. Santosh Kumar to discuss his current research and the effects it could have on future treatment approaches for HIV-induced aging and Alzheimer’s disease. Dr. Kumar is a Professor in the Department of Pharmaceutical Science at the University of Tennessee.

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Guest: Natalia Castillo Almeida, MD

Influenza can increase the risk of hospitalization and disease severity, specifically for high-risk patients. Fortunately, the influenza vaccine can help combat this. Join Dr. Natalia Castillo Almeida, an Assistant Professor in the Division of Infectious Diseases at the University of Nebraska School of Medicine, as she shares key data on hospitalization rates and recommendations for vaccination.

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Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA

Guest: Steve Grinspoon, MD

Many studies over the last few years have shown that the risks of cardiovascular disease have increased between 50 to 100 percent among patients with HIV. So what steps need to be taken to help reduce this risk for our patients? Here to discuss what we need to know is Dr. Mary Katherine Cheeley and Dr. Steven Grinspoon, Professor of Medicine at Harvard Medical School and Chief of the Metabolism Unit at Massachusetts General Hospital.

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Host: Anna Giuliano, PhD

Guest: Joel Heidelbaugh, MD

HPV vaccination guidance for mid-aged adults (27 to 45 years old) was updated by the CDC in 2019. Unfortunately, very few individuals in the US in this age range have ever been vaccinated for HPV, despite the risk for acquiring an HPV infection that can potentially progress to cancer, most notably oropharyngeal, cervical, and anorectal. Join us as Drs. Anna Giuliano and Joel Heidelbaugh discuss strategies for improving HPV vaccination rates across different populations and provide specifics on how and when to use shared clinical decision-making (SCDM) when offering a permissive recommendation.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Paul Kwo, MD
Hepatitis B and C are both highly prevalent infections around the world. However, many individuals are not aware of their infection, which can lead to progressive liver damage and other health consequences. This is just one of the many unmet needs in the hepatitis care continuum, and joining Dr. Charles Turck to help uncover those unmet needs and discuss how the latest management strategies can help address them is Dr. Paul Kwo, Director of Hepatology at Stanford University.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Paul Kwo, MD
Hepatitis B and C are both highly prevalent infections around the world. However, many individuals are not aware of their infection, which can lead to progressive liver damage and other health consequences. This is just one of the many unmet needs in the hepatitis care continuum, and joining Dr. Charles Turck to help uncover those unmet needs and discuss how the latest management strategies can help address them is Dr. Paul Kwo, Director of Hepatology at Stanford University.

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Guest: Jason Goldman, MD
How are standard versus adjuvanted influenza vaccines made? Here to break down the manufacturing process for these types of influenza vaccines is primary care physician Dr. Jason Goldman.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Andrew Clark, MD
Emerging treatment options have helped patients with HIV live longer, but the aging population faces its own unique challenges. To explore how we can combat these challenges—including the ongoing stigma around HIV—Dr. Charles Turck is joined by Dr. Andrew Clark, who is the Global Medical Lead at ViiV Healthcare.

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Host: Charles Turck, PharmD, BCPS, BCCCP
Guest: Paul Hunter, MD
It’s important to recognize that older adults are more susceptible to influenza infection—as well as increased severity of infection—than younger, healthier populations.1 Fortunately, there are vaccines available that can help prevent influenza in this aging population. But do the relative benefits and harms of higher-dose and adjuvanted vaccines, compared with one another and with other influenza vaccines, favor the use of any one or more of these vaccines over other age-appropriate options for people 65 and older?2 That's the exact question the CDC’s Advisory Committee on Immunization Practices (ACIP) sought to answer and what Dr. Charles Turck discusses with Dr. Paul Hunter, Associate Professor in the Department of Family Medicine and Community Health at the University of Wisconsin School of Medicine and Public Health.

References:
1. Centers for Disease Control and Prevention. Fly & People 65 Years and Older. Accessed August 16, 2022. https://www.cdc.gov/flu/highrisk/65over.htm.
2. National Center for Immunization & Respiratory Diseases. Advisory Committee on Influenza Practices. Influenza Vaccines for Older Adults: GRADE Summary. Accessed August 16, 2022.

USA-FLUD-22-0056 December 2022

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Natalia Castillo Almeida, MD

Patients in urban communities often face challenges when accessing influenza vaccines. But there are ways we can help address those geographic and socioeconomic barriers. Joining Dr. Charles Turck to share key strategies for improving influenza vaccination rates in urban communities is Dr. Natalia Castillo, Assistant Professor in the Division of Infectious Diseases at University of Nebraska Medical Center.

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Host: Jennifer Caudle, DO

Guest: Carolyn Bridges, MD

We all know that influenza vaccinations can help prevent serious infections and save lives. But how often do you consider the underrecognized benefits of these vaccines—like how influenza vaccinations can be a cost-effective solution for both patients and the entire healthcare system? Joining Dr. Jennifer Caudle to discuss these underrecognized benefits and how we can educate patients about the benefits of influenza vaccination is Dr. Carolyn Bridges, Director of Adult Immunizations at Immunize.org.

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Host: Kevin Cleveland, PharmD, ANP

Older adults face a variety of unique challenges that increase their risk of serious influenza infections. But fortunately, vaccinations can help address these challenges. Learn more with Dr. Kevin Cleveland, Associate Professor at the Idaho State University College of Pharmacy.

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Host: Christina Madison, BS, PharmD, BCACP, AAHIVP

In the midst of a potential tridemic between COVID-19, RSV, and influenza, it’s now more critical than ever to raise awareness among patients about the importance of flu vaccines. Here to provide counseling strategies for educating patients about flu vaccines is Dr. Christina Madison, Associate Professor of Pharmacy Practice at Roseman University of Health Sciences.

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Host: Jennifer Caudle, DO

Guest: Jennifer Shu, MD, FAAP

Why is are we currently facing a tripledemic? Joining Dr. Jennifer Caudle to uncover what has led to this dramatic increase in COVID-19, RSV, and the flu—and share strategies to combat this tripledemic—is ReachMD Host Dr. Jennifer Shu, a pediatrician at Children’s Medical Group in Atlanta, Georgia.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Fatima, Adhi, MD

Guest: Mei Chang, PharmD

Collaborative care is fundamental for critically ill patients, especially when it comes to medication dosing. To explore key considerations on dosing and share insights from their presentations at IDWeek 2022, Dr. Charles Turck is joined by Dr. Adhi Fatima from the Baylor College of Medicine and Mei Chang from the Montefiore Medical Center at the Weiler Division Einstein Campus.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Jason Zucker, MD

The monkeypox outbreak has taken the nation by storm, leading to an increase in diagnostic and vaccination resources. But has this virus prepared us for future infectious disease outbreaks? Joining Dr. Charles Turck to share lessons we’ve learned from the monkeypox outbreak is Dr. Jason Zucker from the Columbia University Irving Medical Center.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Richard Kojan, MD

As the fight against Ebola continues, can a new biosecure emergency care unit (CUBE) and therapeutic guidelines from the World Health Organization (WHO) help combat this disease? Mario Nacinovich joins study Dr. Richard Kojan, President of the Alliance for International Medical Action, to discuss these new guidelines.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Siwen Wang, MD

Have our patients experienced anxiety, depression, and stress following a COVID-19 infection? Joining Mario Nacinovich to dive into emerging research on post-COVID-19 psychological distress is Dr. Siwen Wang, a researcher in the Department of Nutrition at Harvard T.H. Chan School of Public Health.

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Host: Matt Birnholz, MD

Guest: David Canaday, MD

As we age, our immune system becomes weaker and is therefore unable to ward off infection as easily as in our younger years.1 This is particularly troublesome during flu season. In fact, the CDC’s Advisory Committee on Immunization Practices (ACIP) recently looked at flu vaccine data for adults aged 65 years and older, and they now recommend that this age group preferentially receive higher dose or adjuvanted vaccines over standard dose unadjuvanted vaccines when available.2 So what was the data that led to these updated recommendations? Joining Dr. Matt Birnholz to share those key findings and the role of adjuvanted vaccines like FLUAD® QUADRIVALENT (Influenza Vaccine, Adjuvanted) in preventing influenza in older adults is Dr. David Canaday, Professor in the Division of Infectious Diseases & HIV Medicine at Case Western Reserve University in Cleveland.

Avoid use in patients who have experienced any severe allergic reactions to any component of the vaccine. For more risk information please see below or consult the Full US Prescribing Information for FLUAD® QUADRIVALENT here.

References:
1. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis. 2002;2(11):659-666.
2. Centers for Disease Control and Prevention. Past seasons estimated influenza disease …

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: William Schaffner, MD

Before recommending the new COVID-19 booster, what do we need to know about this vaccine, and which of our patients fit the criteria for it? To learn the latest on what experts have to say about the new COVID-19 booster, Dr. Charles Turck speaks with Dr. William Schaffner from the National Foundation for Infectious Diseases.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Charles P. Gerba, MD

A recent case of polio emerging in New York City have clinicians questioning whether or not we need to be concerned about a spread. What do we need to know about this case—and our potential risk—of polio? Joining Mario Nacinovich to take a look at this case is microbiologist Dr. Charles Gerba, a Professor of Environmental Science at the University of Arizona.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Charles P. Gerba, MD

With rates of monkeypox continuing to rise, what do we need to know about this disease? And how easily can it spread from one person to another? Tune in to hear from renowned microbiologist, Dr. Charles Gerba, a Professor of Environmental Science at the University of Arizona as he explores these topics with Mario Nacinovich.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Julia Bilinska, MD

Guest: Aatish Patel, MD

Monkeypox continues to spread around the globe, and its clinical manifestations can differ from what we’ve seen. What are the newest symptoms of this disease? Learn more about these manifestations from Drs. Aatish Patel and Julia Bilinska from Guy's and St. Thomas' NHS Foundation Trust in London as they talk about their research with Host, Mario Nacinovich.

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Guest: Amy Mgonja, PharmD, BCGP, CPPS

Training pharmacists to administer vaccines can reduce barriers to immunizations and improve patient care. Here to discuss the ApHA Pharmacy-Based Immunization Delivery Program and the important role that pharmacists play in educating and vaccinating patients is Dr. Amy Mgonja, clinical consultant pharmacist at Dawa Rx Consulting.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Nick Kusnezov, MD

Can you balance locum tenens with a full-time career? To answer that question, Dr. Charles Turck is joined by board-certified orthopedic surgeon, Dr. Nicholas Kusnezov, to walk us through his journey from joining the military to locum tenens.

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Host: Jennifer Caudle, DO

Guest: Roni Devlin, MD

As rates of burnout continue to rise in the healthcare community, how can help our female physicians combat it? Dr. Jennifer Caudle joins Infectious Disease Specialist, Dr. Roni Devlin, to discuss how we can prevent burnout for female physicians.

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Host: Jennifer Caudle, DO

Guest: Wendy Wright, DNP, FNP-BC, ANP-BC, FAANP, FAAN, FNAP

Guest: Gary Marshall, MD

It's well understood that annual vaccination is the best way to help reduce the high burden associated with influenza. And while most influenza vaccines available in the United States are produced in eggs, this presents some inherent challenges, which can lead to reduced vaccine effectiveness. Fortunately, alternative production processes can help us overcome those challenges, and to learn more, Dr. Jennifer Caudle speaks with Dr. Wendy Wright and Dr. Gary Marshall.

USA-CRP-22-0018 May 2022

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Host: John J. Russell, MD

Guest: Randy Young, MD

As Monkeypox continues to spread across non-endemic countries more and more, how can we detect it in our patients? And what’s being done to stop the spread? Guest and fellow ReachMD Host Dr. Randy Young, a Pulmonary Disease and Critical Care Medicine physician, joins Dr. John Russell to discuss what physicians should be looking out for, and how this virus has impacted public health.

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Host: Michael Greenberg, MD

Guest: Esther Freeman, MD, PhD

Guest: Steven Chen, MD, MPH, MHPEd

With the recent rise of monkeypox cases around the world, dermatologists will be some of the first to evaluate and diagnose patients with the disease. So to help those on the frontlines, Dr. Esther Freeman, Director of Global Health Dermatology at Massachusetts General Hospital and Dr. Steven Chen, Assistant Professor of Dermatology at Harvard Medical School, share what dermatologists need to know about monkeypox.

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Host: Peter Buch, MD, FACG, AGAF, FACP

The COVID-19 pandemic has entirely transformed the educational community, especially for medical students. To find out more about this impact, Dr. Peter Buch is joined by two fourth-year medical school students, Miss Sheila Eghbali and Mr. Kyle Glose, to discuss their experiences.

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Host: John J. Russell, MD

Guest: Amesh Adalja, MD

Monkeypox is not something we’re used to seeing in non-endemic countries like North America and Europe. Yet its spreading has some experts scratching their heads. Dr. Amesh Adalja, a Senior Scholar at the Johns Hopkins Center for Health Security at the Bloomberg School of Public Health, shares with Dr. John Russell what clinicians need to know about monkeypox amid the global outbreak in non-endemic countries.

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Host: Jennifer Caudle, DO

Guest: Maurice G. Sholas, MD, PhD

After years of serving the New Orleans community, one physician decided to pursue locum tenens work. Dr. Jennifer Caudle joins Dr. Maurice Sholas, a pediatric physical rehabilitation physician, to share his experiences with locum tenens and in New Orleans.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Trevor Cabrera, MD

What’s it like becoming a locum tenens physician right out of residency? Dr. Charles Turck joins Dr. Trevor Cabrera, a Board-Certified pediatrician who trained in Houston, Texas, to share his firsthand experience and offer advice for residents.

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Host: Paul P. Doghramji, MD, FAAFP

Guest: Samantha Conroy, MD

Locum tenens can improve quality of care around the globe—especially in remote and underserved communities. To share how, Dr. Paul Doghramji joins Dr. Samantha Conroy, a family practice obstetrician to share her experiences working as a locum tenens obstetrician in underserved communities.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Trevor Cabrera, MD

What’s it like becoming a locum tenens physician right out of residency? Dr. Charles Turck joins Dr. Trevor Cabrera, a Board-Certified pediatrician who trained in Houston, Texas, to share his firsthand experience and offer advice for residents.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Heather Moday, MD

When we say the words behavior, diet, habits, and environment, chances are you don't think of the body's immune system. But based on recent research, all of those factors play a role in influencing immune function. So how can we keep them in mind and boost our immunity in the face of prevalent diseases, including COVID-19? Find out with Dr. Charles Turck as he speaks with Dr. Heather Moday, author of The Immunotype Breakthrough: Your Personalized Plan to Balance Your Immune System, Optimize Health, and Build Lifelong Resilience.

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Host: Matthew Sorrentino, MD

Guest: William W. Li, MD

Some patients who recover from COVID-19 may continue to experience long-term cardiovascular complications. So what symptoms should we be looking out for? Joining Dr. Matthew Sorrentino to discuss the long-term cardiovascular impacts of COVID-19 is Dr. William Li.

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Host: John J. Russell, MD

Guest: Joseph E. Bavaria, MD

Featuring a wide range of disciplines and a new approach to comprehensive care, what do we need to know about the Aorta Center at Penn Medicine? Dr. John Russell is joined by Dr. Joseph E. Bavaria to dive into this aortic program and discuss a new approach to comprehensive care.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Chris Beyrer, MD, MPH

Amid the ongoing COVID-19 pandemic, countries in Sub-Saharan Africa are also facing high rates of HIV and AIDS prevalence. But after the success of the mRNA COVID-19 vaccines, could an mRNA vaccine for HIV/AIDS be on the horizon? Here to explore emerging research and the potential role that mRNA technology might have in battling this global epidemic is Dr. Chris Beyrer, a Professor of Epidemiology at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Kathryn Gallagher, MS, RN, BSN

Guest: Kate Newcomb-DeSanto, MSN, RN, MSW

What does Penn Medicine’s newly-opened patient room facility have to offer? Dr. Charles Turck is joined by Penn Medicine Clinical Advisors Kathy Gallagher and Kate Newcomb-DeSanto to discuss the new pavilion and how it's revolutionizing patient care.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Sandy Marks

Guest: Kim Horvath, JD

Guest: Kyle Thomson, JD

With telehealth services expanding during the COVID-19 pandemic, has our access to them changed? To better understand this, Dr. Charles Turck meets with Sandy Marks, Kim Horvath, and Kyle Thomson from the AMA to explore what’s been done to provide Medicare coverage during a public health emergency and what’s on the horizon for telehealth access.

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Host: Mimi Secor, DNP, FNP-BC, FAANP

Guest: Maria Trent, MD, MPH, FAAP, FSAHM

Dr. Mimi Secor is joined by Dr. Maria Trent to discuss mycoplasma genitalium (MGen), how we can better understand this infection and help reduce our patients' risk of it.

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Host: Mimi Secor, DNP, FNP-BC, FAANP

Guest: Maria Trent, MD, MPH, FAAP, FSAHM

There are gaps in resources available to care for patients with mycoplasma genitalium (MGen). Since access to testing and to resistance testing are critical to be able to properly care for women suspected of having MGen, Dr. Mimi Secor talks with Dr. Maria Trent from Johns Hopkins School of Medicine about how clinicians can overcome common diagnostic and treatment challenges and shares guidelines updates from the CDC.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Emily Carroll, JD, MSW

The No Surprises Act aims to protect consumers from surprise medical bills. But how exactly does it go about doing that, and what’s the current status of its implementation? Joining Dr. Charles Turck to share progress and challenges associated with the No Surprises Act is Ms. Emily Carroll, a senior legislative attorney for the American Medical Association's Advocacy Resource Center.

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Host: Jennifer Caudle, DO

Guest: Sarah Ali, MD

From working in a big city to taking on an assignment in a small mountain village, Dr. Sarah Ali from the Ventura County Medical Center joins Dr. Jennifer Caudle to talk about her adventures abroad with locum tenens and share key lessons she learned along the way.

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Host: Jerome Lisk, MD

Guest: Tissa Wijeratne MD PhD FRACP FRCP FAAN

Since the onset of the COVID-19 pandemic, researchers and clinicians alike have strived to address the mysteries surrounding the virus, including its long-term side effects on patients. So what we do need to know about the emerging syndrome pointing to COVID-19’s neurological and cognitive impacts? To find out, Dr. Jerome Lisk is joined by Dr. Tissa Wijeratne, the Director of the Department of Neurology and Stroke Services at the University of Melbourne, to talk about post-COVID-19 neurological syndrome.

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Guest: Maureen Brogan, MD

The COVID-19 pandemic has impacted care across all specialties, and the 2021 American Society of Nephrology (ASN) Annual Meeting offered a platform for nephrologists to share their experiences. Tune in to hear how Dr. Maureen Brogan adapted her practice to overcome supply and staffing shortages.

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Host: John J. Russell, MD

Guest: Randy C. Miles, MD, MPH

Are enlarged lymph nodes caught on CT scans following mRNA vaccination cause for concern? Or is it just a case of incidentaloma? Joining Dr. John Russell to answer those and other key questions regarding the link between COVID-19 vaccines and abnormal mammogram findings is Dr. Randy C. Miles.

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Host: Jennifer Caudle, DO

Guest: Erik Munson, Ph.D

Mycoplasma genitalium (M. gen) is an STI that shares similar health consequences to chlamydia and gonorrhea. Further complicating this health threat is the fact that there’s been little guidance on how to manage this new pathogen until recently when the 2021 STI Treatment Guidelines were released. Joining Dr. Jennifer Caudle to talk about M. gen and why the guidelines recommend the use of nucleic acid amplification tests for the diagnosis of this pathogen is Dr. Erik Munson, an Assistant Professor of Clinical Laboratory Science at Marquette University.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Onyema Ogbuagu MBBCh, FACP, FIDSA

With so many questions and confusion points surrounding booster shots, what do we need to know? Dr. Charles Turck is joined by Dr. Onyema Ogbuagu, Associate Professor in the section of Infectious Diseases at Yale University School of Medicine, to answer common questions regarding the COVID-19 vaccine booster shots.

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Guest: Cynthia Leifer, PhD

With variants continuing to emerge, how are the COVID-19 vaccines faring. Here to share how these vaccines are holding up—and what that means for future variants—is Dr. Cynthia Leifer, Professor of Immunology at Cornell University.

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Guest: Cynthia Leifer, PhD

In the midst of a global pandemic, where do vaccine ethics come into play? Dr. Cynthia Leifer, a Professor of Immunology at Cornell University, reviews diversity in clinical trial, the impact of vaccine mandates, and more.

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Guest: Jeniffer Hernandez, PhD

mRNA vaccines are far from the only emerging technology out there. Dr. Jeniffer Hernandez, Associate Professor of Biopharmaceutical Sciences at the Keck Graduate Institute, reflects on where vaccine technology is headed.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Mark Blatter, MD

Despite their crucial role in preventing seasonal influenza, traditional influenza vaccines may not be providing as much protection as we thought, leading researchers to take a look at different methods of vaccine production, specifically cell-based flu vaccine production. Here with Dr. Charles Turck to discuss influenza prevention and the latest evidence supporting a cell-based vaccine option is Dr. Mark Blatter.

USA-QIVc-21-0146 November 2021

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Animesh Ray, PhD

Getting ahead of the next pandemic may be possible thanks to deep machine learning’s ability to predict the structure of antibodies. And while that may sound like science fiction, this technology is currently being studied, which is why Dr. Animesh Ray from the Keck Graduate Institute joins Dr. Charles Turck to provide insight on where the research currently lies and what we have to look forward to.

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Host: Mimi Secor, DNP, FNP-BC, FAANP

Guest: Maria Trent, MD, MPH, FAAP, FSAHM

Dr. Mimi Secor is joined by Dr. Maria Trent, Chief of the Division of Adolescent and Young Adult Medicine at Johns Hopkins School of Medicine, to discuss diagnosing and treating antibiotic resistant MGen.

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Host: Jennifer Caudle, DO

Guest: Charles P. Vega, MD

The development of mRNA vaccines marked a turning point in the battle against the COVID-19 pandemic, but what do we need to know about this emerging vaccine technology? Dr. Jennifer Caudle and Dr. Charles Vega, a Clinical Professor in the Department of Family Medicine at the University of California Irvine, discuss some of the benefits and common concerns.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Jill Foster, MD

From mRNA vaccines to egg-based vaccines, what do we need to know about the different types of vaccines? Dr. Jill Foster, Director of the Division of Pediatric Infectious Diseases and Immunology at the University of Minnesota, joins Dr. Charles Turck to explore what we need to know about the various types of vaccines available.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: René F. Najera, DrPH

Misinformation regarding the COVID-19 vaccines have prevented patients from getting vaccinated. How should we talk to our patients about these misconceptions? Dr. Charles Turck joins epidemiologist, Dr. René Najera, to review leading myths surrounding the COVID-19 vaccines and how we can counsel our patients.

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Guest: Muthiah Vaduganathan, MD, MPH

What do we currently know about the cardiac consequences of the COVID-19 vaccines? Dr. Muthiah Vaduganathan, cardiologist and investigator at Brigham Women's Hospital at Harvard Medical School, addresses the cardiac concerns surrounding the vaccines and how we can talk to patients about them.

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Host: John J. Russell, MD

The global pandemic incited the expedited development of COVID-19 vaccines. But how did that change the development process? ReachMD host and Family Medicine Physician, Dr. John Russell, tells us how the rollout of the COVID-19 vaccine differs from other vaccines and what it could mean for the medical field.

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Host: Paul P. Doghramji, MD, FAAFP

Guest: Mojgan Saber, MD

Can Locum Tenens be an option for healthcare professionals just completing their residency? Dr. Paul Doghramji is joined by Dr. Mojgan Saber to share her own experience as well as tips and tricks for residents looking at Locum Tenens right after residency.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Randy Young, MD

Amid the surge of the Delta variant, critical care physician Dr. Randy Young is traveling to ICUs across the country to help treat patients. Tune in to hear Dr. Young share how this surge is impacting both patients infected with the variant and the healthcare professionals caring for them.

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Host: Charles P. Vega, MD

Guest: Sateria Venable

Regional healthcare disparities are biases that are based on where people live. Are your patients’ treatment options being impacted and limited by their geographical location? Join us as our two experts discuss how to support broader policy issues and highlight the importance of diagnostic algorithms that have been developed with diverse input. These steps may be of value in your clinical practice to ensure all patients have equal access to care regardless of their epidemiologic, socioeconomic, or insurance circumstances.

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Host: Charles P. Vega, MD

Guest: Robert O. Roswell, MD, FACC, FACP

Diversifying our physician workforce so that it is more racially, ethnically, and geographically balanced can ultimately have a positive impact on community health. Join us as two experts discuss how pipeline programs reaching children as early as elementary school can help ensure workplace diversity. Also find out how clinicians can be advocates for their patients by helping to disentangle them from structural inequities and working towards policy changes. There’s a lot than can be done to provide more balanced care, but we need to look beyond simple fixes to the root causes of the issues. So find your bandwidth – that’s what you can do today – and discover why it’s so important to move upstream to solve the problems manifesting downstream.

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Host: Charles P. Vega, MD

Guest: Lionel Phillips, MBA

Learn why diversity in clinical trials is so important to community health. Two experts discuss the key role that trusted messengers play in enrollment, why it is critical to break the cycle of medical mistrust, and the downstream effect of a lack of diversity in clinical trials.

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Host: Charles P. Vega, MD

Guest: Candice Taylor Lucas, MD, MPH, FAAP

What is cultural humility, and how can it be incorporated into clinical practice? How does your patient's culture impact their health behaviors, and why does your culture matter?

Listen in as two leading experts navigate concerns surrounding cultural humility and emphasize the importance of empathy, awareness, and advocacy. Discover ways to integrate small but important changes into your clinical practice to help bridge communication gaps and enable your patients to thrive.

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Host: John J. Russell, MD

In order for us to better understand how mRNA vaccines were able to move beyond clinical trials amid the COVID-19 pandemic, we must first know how they were originally developed. That’s why ReachMD host and family medicine physician Dr. John Russell reviews the history of mRNA vaccines and how we can use them in the future.

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Host: Jennifer Caudle, DO

Host: John J. Russell, MD

“What makes the Delta variant different?” “I keep hearing about breakthrough infections, so are the COVID-19 vaccines effective?”

These are just some of the questions patients now have amid the surge of the Delta variant, and many patients are turning to physicians for answers. That’s why ReachMD hosts and primary care physicians Drs. Jennifer Caudle and John Russell sit down to share their approach to answering these FAQs regarding the Delta variant, the COVID-19 vaccines, and more.

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Host: Jennifer Shu, MD, FAAP

Tune in to hear pediatrician Dr. Jennifer Shu share what we currently know about the risks and impacts of the Delta variant on our youngest patients and perhaps even more importantly, how we can help keep them safe.

Published September 23, 2021

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Host: Jennifer Shu, MD, FAAP

School’s back in session, and that means it’s time we take a look at how we can help keep children safe and healthy both inside and outside the classroom with pediatrician Dr. Jennifer Shu.

Published September 21, 2021

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Pradipta Ghosh, MD

Artificial intelligence (AI) is rapidly changing how we practice medicine in a variety of ways, especially in the midst of the COVID-19 pandemic. In fact, a recently developed AI model can help us predict the disease course of patients infected with COVID-19, and here to share how that model was developed based on pandemics of the past and how it can be used in the current—and even future—pandemics is Dr. Pradipta Ghosh, Professor of Cellular and Molecular Medicine at UC San Diego.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Alberto Augsten, PharmD

During the COVID-19 pandemic, many patients turned to alcohol as a way to cope with this sudden and unprecedented global health crisis, and the rates of alcohol dependency are only continuing to rise according to recent studies. That’s why Dr. Charles Turck speaks with board-certified clinical toxicologist Dr. Alberto Augsten to help us better understand the challenges in screening patients for alcohol dependency amid the COVID-19 pandemic and how we can overcome those barriers to get our patients the best—and necessary—treatment.

Published August 20, 2021

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Shantanu Nundy, MD, MBA

With all of the chaos and changes brought on by the COVID-19 pandemic, it can be easy to focus on the negative impacts of this global health crisis. But for one physician, the same chaos and changes are exactly what forged his unique perspective: one that recognizes the benefits that has come out of the pandemic.

Joining Dr. Charles Turck to share why he believes the COVID-19 pandemic has changed healthcare for the better is primary care physician Dr. Shantanu Nundy, author of a recent article published in The Washington Post titled, “A Surprising Pandemic Side Effect: It Has Improved Healthcare.”

Published June X, 2021

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Guest: Susan Butler-Wu, PhD, D(ABMM), SM(ASCP)

Dr. Susan Butler-Wu, Associate Professor of Clinical Pathology and Director of Medical Microbiology at LAC+USC Medical Center, investigates the differences—and highlights the benefits—of PCR versus antigen testing for COVID-19.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Gail Saltz, MD

The quarantine blues may have come to an end, but as the country continues to reopen, a whole new set of mental health challenges are just beginning. So how can we help our patients who found comfort in social distancing and mask-wearing mandates navigate this change and return to public places? To find out, Dr. Charles Turck speaks with psychiatrist Dr. Gail Saltz, who discusses the lasting effects of the quarantine blues, how we can help patients who are suffering from anxiety, and more.

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Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Paul Nyirjesy, MD

Guest: Christina Muzny, MD

Diagnosing vaginal infections early and accurately is key, but are current testing methods for vaginal infections facilitating early diagnosis? Joining Dr. Charles Turck to help answer this question are Drs. Christina Muzny and Paul Nirjesky, who share their multidisciplinary viewpoints on vaginal infections and diagnostic practices in women’s health.

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Host: Andrew Wilner, MD, FACP, FAAN

Guest: William W. Li, MD

As the number of new COVID-19 infections continues to decrease and the United States begins to open back up, it’s important to note that there are patients who have survived COVID-19 but are still suffering. The newly coined term “COVID long-haulers” refers to those patients who continue to have symptoms even after the acute infection is resolved. Joining Dr. Andrew Wilner to share what we know so far about COVID long-haulers and how we can help them is vascular biologist Dr. William Li.

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Host: Neilanjan Nandi, MD

Guest: Jessica Allegretti, MD, MPH

Also known as C. diff for short, Clostridium difficile is an extremely difficult intestinal disease to manage…but not an impossible one. Joining Dr. Neil Nandi to share her insights on how to best mange C. diff in IBD patients is Dr. Jessica Allegretti, the Associate Director of the Crohn's and Colitis Center and the Director of the Fecal Microbiota Transplant Program at the Brigham and Women's Hospital in Boston, Massachusetts.

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Host: Neilanjan Nandi, MD

Guest: Jessica Allegretti, MD, MPH

Bezlotoxumab is an IV antitoxin infusion treatment option for Clostridium difficile (C. diff) that’s been shown to reduce recurrence in IBD patients…so why isn’t it being used as much as it should be? Here to share the latest data and insights on bezlotoxumab as a treatment option for IBD patients with C. diff is Dr. Jessica Allegretti, Associate Director of the Crohn's and Colitis Center and Director of the Fecal Microbiota Transplant Program at the Brigham and Women's Hospital in Boston, Massachusetts.

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Host: Peter Buch, MD, FACG, AGAF, FACP

Guest: Colin T. Swales, MD

How can we help the two to four million Americans who are living with hepatitis C? Joining Dr. Peter Buch to answer this question and share treatment strategies for various case scenarios is hepatologist Dr. Colin Swales, Assistant Medical Director of Transplant Services at Harvard Hospital.

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Host: Jennifer Caudle, DO

Guest: Kelly Cawcutt, MD

How has the COVID-19 pandemic changed vascular access paradigms in the intensive care unit? Joining Dr. Jennifer Caudle to share her story and lessons learned from the pandemic is Dr. Kelly Cawcutt, an Assistant Professor in the Department of Internal Medicine and the Associate Medical Director of Infection Control and Epidemiology at the University of Nebraska Medical Center.

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Host: Jennifer Caudle, DO

Guest: Archana Chatterjee, MD, PhD

Since adults 65 years and older bear the greatest burden of severe disease from influenza, it’s critically important to ask ourselves the following question: what can we do to better prevent seasonal influenza infections in older adults? Here to answer that and other practical questions is Dr. Archana Chatterjee, MD, PhD, Dean of the Chicago Medical School and Vice President for Medical Affairs at Rosalind Franklin University in Chicago, IL.

USA-CRP-21-0004 January 2021

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Host: Andrew Wilner, MD, FACP, FAAN

Guest: Jennifer A. Frontera, MD

Most commonly associated with respiratory symptoms, COVID-19 infections have led to a myriad of neurological symptoms such as encephalopathy and stroke. Dr. Andrew Wilner joins Dr. Jennifer Frontera, a neurocritical care specialist and professor of neurology at the NYU Grossman School of Medicine, to discuss obstacles that neurologists have faced during the COVID-19 pandemic.

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Host: Jennifer Caudle, DO

Guest: Paul Jarris, MD, MBA

Since the COVID-19 vaccines received an emergency use authorization, tracking possible adverse reactions in real time becomes even more important. But what are some of the limitations we’re facing in doing so, and how can we overcome them? To find out, Dr. Jennifer Caudle speaks with Dr. Paul Jarris, Chief Medical Advisor for MITRE Corporation.

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Host: Andrew Wilner, MD, FACP, FAAN

Guest: Ken Tyler, MD

Further complicating the COVID-19 pandemic is the emergence of viral variants. Dr. Ken Tyler from the University of Colorado School of Medicine shares with us what we know so far about the COVID-19 variants that are quickly spreading around the world.

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Host: Andrew Wilner, MD, FACP, FAAN

Guest: Ken Tyler, MD

To find out what we currently know about the neurological complications caused by COVID-19, Dr. Andrew Wilner speaks with Dr. Ken Tyler, Professor and Chair of the Department of Neurology at the University of Colorado School of Medicine.

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Host: Matthew J. Sorrentino, MD, FACC, FASH

Guest: Suneet Mittal, MD FACC FHRS

The development of cardiac devices enhanced by wireless remote monitoring has changed the way cardiologists care for their patients. With that in mind, Dr. Matthew Sorrentino discusses remote monitoring in cardiology with Dr. Suneet Mittal, medical director of the Snyder Center for Comprehensive Atrial Fibrillation at the Valley Hospital in Ridgewood, New Jersey.

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Host: John J. Russell, MD

Social distancing is surprisingly not a new concept in the United States. As our country geared up for World War I in 1918, social gatherings and parades to support the military were at an all-time high. But as feelings of patriotism spread at these events, so too did influenza. Join Dr. John Russell as he recounts The Tale of Two Cities: Philadelphia and St. Louis and how the spread of influenza was dramatically different between the two cities due to the actions each took to mitigate risk.

Published March 28, 2020

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Host: Matt Birnholz, MD

Healthcare workers face a new threat beyond the difficult prospects of overrun hospitals, PPE shortages, and incidental spread of the virus to their loved ones. As the pandemic escalates, shifting perceptions and moods from the public have put some clinicians in the crosshairs.

Published March 27, 2020

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Host: Matt Birnholz, MD

Strategies of self-isolation from caregivers treating patients with COVID-19 are taking an emotional toll, cutting them off from their support networks at a time when workplace stress is at an all-time high. But the alternative, to many, is unthinkable.

Published March 27, 2020

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Host: Matt Birnholz, MD

Emerging reports are painting a far more complex picture of clinical presentations for COVID-19 than previously thought, stemming to exceptionally high viral loads in nasal cavities. How will this affect the risk profile for otolaryngologists performing essential ENT procedures?

Published March 27, 2020

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Host: Matt Birnholz, MD

Reports from hospitals in multiple states speak to a rapidly diminishing supply of personal protective equipment, leading healthcare systems to adopt alternative solutions to the shortage. But will these approaches meet the rising demand, and will clinicians be adequately protected along the way?

Published March 23, 2020

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Host: Matt Birnholz, MD

COVID-19 has irreversibly altered the progression track for the next generation of physicians, with cancellations of Match Day events, Board exams, and clinical rotations in effect. Now an increasing number of entities are calling on medical students to join front-line efforts to combat the virus.

Published March 23, 2020

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Host: Matt Birnholz, MD

Among the most touted candidates in the hunt for effective coronavirus treatments are the antimalarial drugs chloroquine and its derivative, hydroxychloroquine. Will these drugs become effective treatment and post-exposure prophylaxis agents?

Published March 23, 2020

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Host: Anne O'Donnell, MD

Guest: Robert "Brinkley" Sewell

Please note: This activity is no longer available for continuing education credit.

The successful management of nontuberculous mycobacteria lung disease (NTM-LD) remains challenging owing to the need for long-term treatment, the ongoing risks of adverse drug reactions, and the potential for nonadherence. These factors underscore the importance of specialty referral and shared decision making in the successful management of NTM-LD, as Dr. Anne O’Donnell and her patient Brinkley exemplify.

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Host: Mario R. Nacinovich, Jr., MSc

Guest: Kalin Clifford, PharmD

Focusing on hospital-acquired and ventilator-associated pneumonia in older adults, Mario Nacinovich is joined by Dr. Kalin Clifford at the American Society of Consultant Pharmacists Annual Meeting. Together they dive deep into these two types of pneumonia to reveal new guidelines and the latest treatment options.

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Host: Matt Birnholz, MD

Guest: Peng Zhang, PhD

Oxygen: It's the third most abundant element in our universe. From healthcare to industrial needs, we know oxygen's uses to be far-reaching, but could there still be more therapeutic potential yet?

In an in-depth conversation with Dr. Matt Birnholz, Dr. Pang Zheng presents new evidence of oxygen's potential uses within the healthcare industry.

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Host: Jennifer Caudle, DO

Guest: Lisa Ipp, MD

Although most college students in the U.S. believe it is important to get an annual influenza vaccine, less than half say they typically get vaccinated, according to results from a new National Foundation for Infectious Diseases (NFID) survey. Motivating college students to get their annual flu vaccinations remains a public health challenge that many health care officials have struggled to overcome.

Host Dr. Jennifer Caudle chats with Dr. Lisa Ipp about the results and takeaways from this survey and what methods and strategies would be the most effective in encouraging more students to get vaccinated.

Dr. Ipp is a Associate Professor of Clinical Pediatrics at Weill Cornell Medicine and Associate Director of Adolescent Medicine at New York-Presbyterian Komansky Children’s Hospital. She also serves as a board member for the National Foundation for Infectious Diseases (NFID)

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Host: John J. Russell, MD

Guest: Meredith Wadman, BM, BCh, M.S.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses.

In June 1962, a young biologist in Philadelphia, using human tissue samples sent from Sweden, produced a line of cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a massive German measles epidemic, the vaccine that would one day wipe out homegrown rubella was introduced. This vaccine has since protected more than 150 million people in the United States, and its development method has also led to other vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles, and adenovirus.

Host Dr. John Russell chats with Meredith Wadman, author of The Vaccine Race: Science, Politics, and the Human Costs of Defeating Disease, about the story of both the science of this urgent race and the political and ethical controversies that nearly ended it prematurely.

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Host: Matt Rosenberg, MD

Guest: Aiden Harrington, ANP, CNM

Current CDC Treatment Guidelines include transgender men and women as special populations. These guidelines recommend risk assessment based on current anatomy and sexual behaviors and screening for asymptomatic STIs based on the patient's history and sexual practices.

At a recent live event recorded in Chicago, moderator Dr. Matt T. Rosenberg welcomes Aiden Harrington, ANP, CNM from Howard Brown Health in Chicago, Illinois. Topics covered include health risks in the LGBTQ community, STI screening and treatment, and how to discuss sexuality with your patients.

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Host: John J. Russell, MD

Do pets help prevent allergies? Does the 5-second rule actually exist? And is dirt really good for a child’s immune system?

Host Dr. John Russell talks with Jack Gilbert, Ph.D., Professor of Surgery at the University of Chicago and Director of the Microbiome Institute. Dr. Gilbert is author of the book Dirt is Good,answering questions about the potential benefits of exposure to germs and bacteria. He and Dr. Russell sift through common misconceptions about microbiomes to better understand their actual risks and benefits for the body's immune system, explaining its role in disease and health.

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Host: Kathy King, RDN

Lyme disease is one of the most puzzling illnesses on the planet. Anyone who has suffered from its debilitating symptoms knows the frustrations of trying to find a cure.

Joining host Kathy King is Dr. Bill Rawls, physician and author of the book Unlocking Lyme: Myths, Truths and Practical Solutions for Chronic Lyme Disease. Dr. Rawls, who overcame Lyme disease himself, gives a comprehensive, practical review of clinical approaches.

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Host: Matt Birnholz, MD

Guest: Robert McNally, MD

From the Villanova Health Summit's Speaker Event, host Dr. Matt Birnholz speaks with guest Dr. Robert McNally, President, and CEO of GeoVax, Inc. They discuss the challenges that biotech companies face when bringing vaccines through clinical trials, and the long-term project being conducted by his colleagues to deliver an HIV vaccine to market.

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Host: John J. Russell, MD

Infectious disease has the terrifying power to disrupt everyday life on a global scale, overwhelming public and private resources and bringing trade and transportation to a grinding halt.

Host Dr. John Russell sits down with Dr. Osterholm to talk about the book Deadliest Enemy: Our War Against Killer Germs. They talk about how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.

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In this session of Beyond the Data carrying forward ideas discussed at CDC's Public Health Grand Rounds, Dr. Phoebe Thorpe speaks with Dr. Bobbi Pritt, Director of the Clinical Parasitology Laboratory and Co-Director of Vector-borne Diseases Laboratory Services at the Mayo Clinic. The two expand on Dr. Pritt's lecture focusing on advances in diagnosing tickborne diseases.

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Host: John J. Russell, MD

Host Dr. Russell sits down with Dr. Steven Hatch, an infectious disease specialist and author of the book, Inferno: a Doctor's Ebola Story, about his experience in Liberia during the heart of the Ebola crisis.

Dr. Steven Hatch first came to Liberia in November 2013, to work at a hospital in Monrovia. Six months later, several of the physicians Dr. Hatch had mentored and served with were dead or barely clinging to life, and Ebola had become a world health emergency. Hundreds of victims perished each week; whole families were destroyed in a matter of days; so many died so quickly that the culturally taboo practice of cremation had to be instituted to dispose of the bodies. With little help from the international community and a population ravaged by disease and fear, the war-torn African nation was simply unprepared to deal with the catastrophe.

A physician’s memoir about the ravages of a terrible disease and the small hospital that fought to contain it, Inferno is also an explanation of the science and biology of Ebola: how it is transmitted and spreads with such ferocity. And as Dr. Hatch notes, while Ebola is temporarily under control, it will inevitably re-emerge―as will …

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Host: Ana Maria Rosario

Guest: David Gandell, MD

Genital Herpes Simplex Virus (HSV) infection is a major public health problem. A dramatic upsurge in genital HSV infections have been documented from several prominent studies, making recognition, treatment, and patient counseling strategies more important than ever.

Joining host, Ana Rosario at the Women's Health Annual Visit in Deerborn, MI, is Dr. David Gandell, Clinical Professor of Obstetrics and Gynecology at the University of Rochester and attending phsyician at Strong Memorial Hospital.

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Host: Jennifer Caudle, DO

News about the Zika virus have dominated health headlines, but understandings about the full range of viral transmission routes, symptomatology, complications, and rising endemic zones remain unclear for many clinicians.

Joining Dr. Jennifer Caudle for updates in recognitions and treatment for Zika virus infection is Dr. Kecia Gaither, practicing OB/GYN and maternal fetal medicine specialist, and perinatal consultant at St. Lukes Hospital in Kansas City, Missouri. Most recently, Dr. Gaither served as Director of Perinatal Outreach at Montefiore Medical Center and Albert Einstein College of Medicine. Prior to this post, she served as the Vice Chairman and Director of Maternal Fetal Medicine in the Department of Obstetrics & Gynecology at Brookdale University Hospital and Medical Center. Dr. Gaither earned her MPH in health policy and management at Columbia University.

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Host: John J. Russell, MD

A fascinating and shocking historical exposé, The Malaria Project is the story of America's secret mission to combat malaria during World War II—a campaign modeled after a German project which tested experimental drugs on men gone mad from syphilis. Karen M. Masterson, a journalist turned malaria researcher, uncovers the complete story behind this dark tale of science, medicine and war.

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A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients. Flume PA, VanDevanter DR, Morgan EE, Dudley MN, Loutit JS, Bell SC, Kerem E, Fischer R, Smyth AR, Aaron SD, Conrad D, Geller DE,Elborn JS. J Cyst Fibros. 2016 Jul;15(4):495-502. doi: 10.1016/j.jcf.2015.12.004. Epub 2016 Feb 4.

Abstract RATIONALE:

For patients with cystic fibrosis (CF), the use of inhaled antibiotics has become standard of care to suppress chronic Pseudomonas airways infection. There are limited antibiotic options formulated and approved for inhaled use and antibiotic efficacies attenuate over time, making additional inhaled antibiotic classes desirable. APT-1026 (levofloxacin inhalation solution, LIS) is a fluoroquinolone in development for management of chronic P. aeruginosa airways infection in patients with CF.

OBJECTIVES:

To compare the safety and efficacy of a 28-day course of treatment with LIS 240mg or placebo BID in persons ≥12years old with CF and chronic P. aeruginosa infection.

METHODS:

A multinational, randomized (2:1), double-blinded study of LIS and placebo over 28days in CF patients ≥12years with chronic P. aeruginosa infection. Time to exacerbation was the primary endpoint. FEV1 (% predicted) and patient-reported …

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Microbial colonization and lung function in adolescents with cystic fibrosis. Hector A, Kirn T, Ralhan A, Graepler-Mainka U, Berenbrinker S, Riethmueller J, Hogardt M, Wagner M, Pfleger A, Autenrieth I, Kappler M, Griese M, Eber E, Martus P, Hartl D. J Cyst Fibros. 2016 May;15(3):340-9. doi: 10.1016/j.jcf.2016.01.004. Epub 2016 Feb 5.

Abstract With intensified antibiotic therapy and longer survival, patients with cystic fibrosis (CF) are colonized with a more complex pattern ofbacteria and fungi. However, the clinical relevance of these emerging pathogens for lung function remains poorly defined. The aim ofthis study was to assess the association of bacterial and fungal colonization patterns with lung function in adolescent patients with CF. Microbial colonization patterns and lung function parameters were assessed in 770 adolescent European (German/Austrian) CF patients in a retrospective study (median follow-up time: 10years). Colonization with Pseudomonas aeruginosa and MRSA were most strongly associated with loss of lung function, while mainly colonization with Haemophilus influenzae was associated with preservedlung function. Aspergillus fumigatus was the only species that was associated with an increased risk for infection with P. aeruginosa.Microbial interaction analysis revealed three distinct microbial clusters within the longitudinal course of CF lung disease. …

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Host: Jennifer Caudle, DO

Dr. Mary Guinan was one of the first scientists to conduct an initial investigation into the emerging HIV/AIDS epidemic for the Center for Disease Control and Prevention. Additionally, she was one of the first female physicians to work on smallpox eradication and has been a leading researcher and educator on sexually transmitted diseases.

Dr. Mary Guinan is the founding dean of the School of Community Health Sciences at the University of Nevada, Las Vegas, and is now a professor emerita.

She joins Dr. Jennifer Caudle to discuss her book, Adventures of a Female Medical Detective which explores Dr. Guinan's life in medicine, including her many experiences with emerging disease outbreaks and the efforts to control them. She provides a unique female perspective from a time when very few women worked in the field.

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Host: Maurice Pickard, MD

STDs are widespread in all walks of life, regardless of gender, race, social status, or education. Seduced into complacency by the notion that "it can't happen to me" many sexually active teens and young adults are stunned when they are diagnosed with an STD.

In Seductive Delusions: How Everyday People Catch STDs, author and physician Dr. Jill Grimes reveals the truths about sexually transmitted diseases through narrated accounts of young men and women, their exam room conversations with doctors, and both the physical symptoms and the emotional reactions that can accompany infection.

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Host: John J. Russell, MD

In recent years, malaria has emerged as a cause celebre for voguish philanthropists. Bill Gates, Bono, and Laura Bush are only a few of the personalities who have lent their names--and opened their pocketbooks--in hopes of stopping the disease. Still, in a time when every emergent disease inspires waves of panic, why aren't we doing more to tame one of our oldest foes? And how does a pathogen that we've known how to prevent for more than a century still infect 500 million people every year, killing nearly one million of them?

In The Fever, journalist Sonia Shah sets out to answer those questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Dr. John Russell hosts this fascinating discussion about her book.

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Host: Matt Birnholz, MD

In the ongoing global campaign to prevent, treat, and cure HIV and AIDS, there have been countless therapeutic approaches targeting the HIV virus and everything it interacts with on the path to infection. But after decades of relentless infectivity claiming over 25 million lives, what if we could one day simply edit and delete the HIV virus right out of existence?

Joining Dr. Matt Birnholz to discuss a novel research effort to leverage gene editing technology in the fight against HIV is Dr. Kamel Khalili, Professor and Chair of the Department of Neuroscience, Director of the Center for Neuro-virology, and Director of the Comprehensive Neuro-AIDS Center at the Lewis Katz School of Medicine at Temple University.

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Recent outbreaks of vaccine-preventable diseases in the United States have prompted clinicians, public health officials and the public to pay closer attention to the growing phenomenon of vaccine refusal. A new study looks at the role of vaccine refusal and the risk of measles and pertussis. In recent years, a substantial proportion of US measles cases occurred in people who were intentionally unvaccinated. Vaccine refusal was also found to be associated with an increased risk of pertussis in some populations.

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Host: John J. Russell, MD

Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. But which one, and how?

In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, prizewinning journalist Sonia Shah interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.

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Guest: Anthony S. Fauci, MD

This week on Conversations on Health Care, hosts Mark Masselli and Margaret Flinter speak with Dr. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. Dr. Fauci is world renowned for his work battling HIV/AIDS and discusses the current efforts at NIAID, along with other global agencies, to contain and control the Zika pandemic.

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Host: Thomas C. Wright, Jr., MD

How should clinicians educate patients on recommended timing intervals for receiving pap smears based on updated guidelines? And for those patients who receive a positive HPV test, what counseling strategies and treatment pathways would be most helpful?

Joining Dr. Thomas Wright from Omnia Education's Women's Health Annual Visit in Boston, MA is Dr. Dana Gossett, Division Chief of General Obstetrics and Gynecology at Northwestern Medical Faculty Foundation and Associate Professor at Northwestern University Feinberg School of Medicine.

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Sepsis is a clinical syndrome of physiologic, pathologic, and biochemical abnormalities caused by serious infection. Sepsis is a major public health concern. Besides being a leading cause of mortality worldwide, sepsis accounted for more than $20 billion of U.S. hospital costs in 2011. In addition, there is increasing awareness that patients who survive sepsis are often left with long-term disabilities.

Updated definitions and clinical criteria for sepsis should help promote earlier recognition and more timely treatment of patients with sepsis or suspected sepsis. In a related study, researchers reviewed the electronic health records of more than one million patients to assess the usefulness of a clinical score known as "SOFA", which is used to help identify patients with sepsis.

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Host: Brian P. McDonough, MD, FAAFP

Reporting from the Caribbean island of Bonaire, Dr. Brian McDonough provides an update on local public sentiments and concerns around the continuing spread of Zika virus infections across the world.

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Drug diversion is the illegal distribution or abuse of prescription drugs or their use for unintended purposes. The diversion of prescription drugs may occur at any point as prescription drugs are distributed from the manufacturer to wholesale distributors, to pharmacies, and ultimately to the patient. Though this problem is nearly universal among healthcare instititions, many don't have adequate processes in place to detect it. Moreover, concerns about civil and regulatory liability, as well as negative publicity, often impede healthcare organizations from reporting instances of drug diversion.

Dr. Howard Zucker, New York State Department of Health Commissioner, speaks with noted provider drug diversion expert Kimberly New, JD, BSN, RN about how prevalent the problem of drug diversion is, the signs of potential drug diversion activity, and how to set up a robust facility program to avert potential diversion events.

This program is provided on behalf of the New York One and Only Campaign, a public health effort led by the Centers for Disease Control and Prevention (CDC) and the Safe Injection Practices Coalition (SIPC) to raise awareness among patients and healthcare providers about safe injection practices.

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CDC's Dr. Phoebe Thorpe speaks with Dr. Sherif Zaki about the important work being done to further reduce the risk of unusual transplant-associated infections.

Ensuring that organs are safe requires:

  • Involvement by many disciplines including: pathologists, epidemiologists, clinicians, and others
  • Global collaboration between federal and state agencies as well as academic institutions
  • Continued focus on improving regulations and screening procedures

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Preschool children who experience repeated episodes of severe lower respiratory tract infections (LRTI) often present with symptoms like wheezing and difficulty breathing. A new study looked at whether the use of the common antibiotic, azithromycin, would help prevent progression of the illness, if given early enough in the episode.

Researchers from Washington University in Saint Louis School of Medicine, studied more than 600 children, ranging from ages one to six years old, with a history of repeated episodes of severe respiratory illness. Children were randomly assigned to either receive azithromycin or a placebo early in these episodes.

They found that children in the antibiotic group experienced a lower risk of progressing to severe LRTI than the placebo group.

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Global health security is the protection of the health of people and societies worldwide. With diseases a plane ride or border crossing away, the importance of global health security has never been clearer. Patterns of global travel and trade pose greater opportunities for infectious diseases to emerge and spread nearly anywhere within 24 hours. The Ebola epidemic in West Africa, which has infected more than 28,000 people across 10 countries and has caused more than 11,200 deaths, highlights the importance of ensuring that every country is prepared to prevent, detect, and respond to outbreaks and emerging health threats.

In this session of Public Health Grand Rounds from the CDC, experts discuss how CDC, other U.S. government agencies, and global partners are working to promote global health security as an international priority and accelerate progress toward a world safe and secure from epidemics of infectious disease.

For more details on this Grand Rounds session and its participants, click here.

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Host: Matt Birnholz, MD

Joining host Dr. Matt Birnholz is Sarah Marchal Murray, Chief Operating Officer at The END Fund, a private philanthropic initiative dedicated to controlling and eliminating neglected tropical diseases (NTDs). Over 1.4 billion people globally are affected by one or more of the most common NTDs, including 875 million children. The END Fund focuses on tackling the five most prevalent NTDs: intestinal worms,schistosomiasis,lymphatic filariasis,trachoma, and river blindness.

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In the United States, seasonal influenza epidemics are responsible for an estimated 226,000 hospitalizations and between 3,000 and 49,000 deaths each year. Pneumonia, the leading infectious cause of hospitalization and death in the United States, is a serious complication of influenza. A new study examined whether getting a flu shot can help reduce hospitalizations due to influenza pneumonia.

Researchers from Vanderbilt University Medical Center evaluated more than 2,700 patients from January 2010 to June 2012. All patients had pneumonia and were admitted to the hospital from the emergency department. Overall, about six percent of patients had pneumonia due to influenza.

Researchers estimated that the patients who received influenza vaccine had a 57 percent less chance of getting hospitalized with influenza-pneumonia than those patients who were not vaccinated.

[Watch more videos of The JAMA Report]

JAMA Report videos provided pursuant to license. ©2015 American Medical Association, publisher of JAMA® and The JAMA Network® journals.

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Host: Brian P. McDonough, MD, FAAFP

Dr. Brian McDonough welcomes Dr. Gregory Weinstein, Professor and Vice Chair and the Director of the Division of Head and Neck Surgery. He is the Co-Director of The Center for Head and Neck Cancer in The Department of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania. The two discuss a dramatic rise in HPV-related cancers over the past decade, and what clinicians need to be aware of in assessing their patients for these indidious diseases.

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Host: Alan S. Brown, MD, FACC, FAHA, FNLA

In this session of Lipid Luminations, host Dr. Alan Brown welcomes Dr. Merle Myerson, founder and director of the Cardiovascular Disease Prevention Program, Lipid Clinic, Pre-Exercise Heart Screening Program, and Cardiology Section/Institute for Advanced Medicine (HIV) at Mount Sinai St. Luke's and Mount Sinai Roosevelt Hospitals. Dr. Myerson reviews the guidelines for prevention, diagnosis, and management of dyslipidemia in patients with HIV.

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Host: John J. Russell, MD

A cure for HIV? Two men, known in medical journals as the Berlin Patients, were cured of HIV in distinct yet related ways. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time. Her book, CURED: How The Berlin Patients Defeated HIV and Forever Changed Medical Science, explores this new field of investigation and paradign shift in HIV treatment inspired by the Berlin Patients. Dr. John Russell hosts.

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Host: John J. Russell, MD

The beginning of AIDS epidemic has been traced to a single event, localized rather precisely in place and time. David Quammen's book, The Chimp and the River: How AIDS Emerged from an African Forest explores these origins. Dr. John Russell's interview with David Quammen explores the real story of AIDS—how it originated with a virus in a chimpanzee, jumped to one human, and then infected more than 60 million people.

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Host: Matt Birnholz, MD

Antibiotic stewardship, or the responsible prescribing habits of antibiotics, is on the decline in the U.S, and the spread of multidrug resistant bacterial infections through communities has already begun to be observed. Dr. Steven Brown, staff physician at Mercy Hospital in St. Louis, MO and Medical Director of the Lung Injury Center, likens antibiotic prescription expectations by patients to that of gameshow participants, where everyone presumes to take home a "prize" of some kind by the end of the encounter. How can clinicians counteract this trend in antibiotic prescription habits, and what are the risks of ignoring this mandate for better stewardship?

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Host: Lee Freedman, MD

Oropharyngeal cancer is part of a growing proportion of head and neck malignancies. This has also been associated with the increase in infection of the oropharynx by oncogenic strains of the human papillomavirus (HPV). And, transoral robotic surgery, or TORS, has allowed for minimally invasive surgery for HPV-related and non-HPV-related oropharyngeal cancer. To discuss this topic and much more, host Dr. Lee Freedman welcomes Dr. Gregory Weinstein, Professor and Vice Chair and the Director of the Division of Head and Neck Surgery. He is also the Co-Director of The Center for Head and Neck Cancer in The Department of Otorhinolaryngology: Head and Neck Surgery at the Hospital of the University of Pennsylvania.

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Host: Frank Russomano

"When political considerations trump basic medical strategies proven effective over centuries, the danger can be grave." That's a passage taken from a recent article called "The Deadly Politicization of Ebola," written by Dr. Richard Amerling, guest on this episode of Voices. Dr. Amerling is President of The Association Of American Physicians And Surgeons. He is Associate Professor of Clinical Medicine and a renowned academic nephrologist at the Beth Israel Medical Center in New York City.

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This week, Mark and Margaret speak with Dr. Arjun Srinivasan, Associate Director for Healthcare Associated Infection Prevention Programs, Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention. Dr. Srinivasan is a prominent spokesman for the CDC's response to the Ebola crisis, as well as an expert on the rise of antibiotic resistant bacteria, which has killed an estimated 75 thousand Americans through hospital acquired infections.

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The Gender, Sexuality and HIV Prevention Center at Ann & Robert H Lurie Children's Hospital of Chicago is the first of its kind facilty for adolescent patients.  Host Dr. Jennifer Caudle welcoms the center's director, Dr. Robert Garofalo. Dr. Garofalo will share the center's mission of supporting multidisciplinary academic subjects including sexual health, gender, sexuality, HIV prevention and health disparities which affect adolescent and young adult populations at risk of acquiring HIV. The Center partners with similar organizations throughout the country in creating an environment where clinicians, academics and scientists can collaborate to design projects with public health significance.

Robert Garofalo, MD, MPH, is Professor of Pediatrics and Preventive Medicine at Northwestern University Feinberg School of Medicine. He is also an Attending Physician at Lurie Children's, where he directs the Adolescent/Young Adult HIV Program. Dr. Garofalo is a national authority on LGBT health issues, adolescent sexuality, and HIV clinical care and prevention.

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Host: Brian P. McDonough, MD, FAAFP

What are the differences in managing the Ebola virius in Africa versus the United States? It has been relatively controlled to date, but what are the major concerns in spreading? Host Dr. Brian McDonough welcomes special guest Dr. Kamar Adeleke, cardiologist in New Castle, Delaware, whose practice includes frequent travels to Nigeria where he teaches at affiliated medical schools. 

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Host: Matt Birnholz, MD

Twenty-five years ago CDC played a pivotal role in the discovery of the virus that causes hepatitis C. After the isolation of HCV, implementation of screening of blood products and organs for donation led to a decrease in rates of HCV infection between 1990 and 2009. In spite of these successes, HCV still remains a serious threat, both domestically and abroad. HCV remains the most common chronic blood borne infection in the United States, affecting approximately 3.9 million individuals. However up to 50% of HCV-infected persons are unaware of their infection. Globally, there are 180 million people who are chronically infected with the virus, and 3-4 million new infections occur every year.

Recent therapeutic advances hold the potential to halt the progression of HCV infection and disease. While HCV-infected persons can be effectively treated, more effort is needed to screen, diagnosis, treat and provide continuity of care. This session of Public Health Grand Rounds will discuss how new screening guidelines, testing methods and therapeutic advances will provide us with an opportunity to improve individual outcomes and to eventually eliminate HCV infection.

To view the complete video recording of this and other CDC Public Health Grand Rounds sessions, visit http://www.cdc.gov/about/grand-rounds/

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Host: Ana Maria Rosario

Guest: David Gandell, MD

Genital herpes is a common sexually transmitted disease. However, it is also one that is commonly underrecognized and misdiagnosed. Senior reporter Ana Maria Rosario chats with Dr. David L. Gandell to discuss genital herpes, from its prevalence to presentation of symptoms, treatment options, and ongoing therapy. Of particular focus within their discussion is the importance of counseling patients through the course of diagnosis and treatment. Dr. Gandell is a Clinical Professor of Obstetrics and Gynecology from the University of Rochester, Strong Memorial Hospital in Rochester, NY.

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Host: Mimi Secor, DNP, FNP-BC, FAANP

Guest: Helen Carcio, NP

Mimi Secor is joined by Nurse practitioner Helen Carcio, Associate Professor in the Graduate School of Nursing at the University of Massachusetts in Amherst. Director of the Health and Continence Institute in South Deerfield, Massachusetts. Ms. Carcio trains doctors and advanced practice clinicians in how to set up community based continence centers.

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Host: John J. Russell, MD

Author and journalist Molly Caldwell Crosby joins host Dr. John Russell to discuss her second book, Asleep: The Forgotten Epidemic that Remains One of Medicine's Greatest Mysteries. Asleep is another fascnating look into medical history.  In the 1920s and '30s, a team of neurologists investigated a rare but disturbing group of patients spread across various hospitals and insane asylums to try to solve the worldwide epidemic of encephalitis lethargica, or sleeping sickness.

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Host: John J. Russell, MD

Host Dr. John Russell welcomes author and journalist Molly Caldwell Crosby to discuss her first book, THE AMERICAN PLAGUE: The Untold Story of Yellow Fever, the Epidemic That Shaped Our History. The discussion focuses on one of history's most controversial human studies - the story of yellow fever and how it overshadowed this country, and in Africa, where even today it strikes thousands every year.

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Host: Matt Birnholz, MD

Tuberculosis is an ancient disease that remains an important global cause of morbidity and mortality. In most cases, TB can be treated and cured by taking a combination of several drugs for 6 to 12 months. When inappropriate or incomplete treatment takes place, however, TB bacteria can develop multidrug resistance (MDR). Annually, there are approximately 500,000 cases of MDR TB, and 150,000 deaths. Although there are simple rapid tests that have improved the diagnosis of the disease, there is immense potential to increase the number of persons diagnosed with MDR TB, and to do so more quickly to initiate treatment sooner.

This session of CDC′s Public Health Grand Rounds will explore how more patients can benefit from advances in diagnostic and treatment options, resulting in an overall reduction in morbidity from MDR TB. The role of CDC, WHO and other partners in combating this public health epidemic will also be discussed.

To view the complete video recording of this and other CDC Public Health Grand Rounds sessions, visit http://www.cdc.gov/about/grand-rounds/

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Host: John J. Russell, MD

A horrifying epidemic of smallpox was sweeping across North America when the War of Independence began, and until now we have known almost nothing about it. Author Elizabeth A. Fenn is the first historian to reveal how deeply Variola affected the outcome of the war in every colony and the lives of everyone on the continent. Join Dr. John Russell in exploring Fenn's innovative work, which brings to light how this megatragedy was met and what its consequences were for the young republic.

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Host: John J. Russell, MD

When the next pandemic arrives, what will it look like? From which innocent host animal will it emerge? Will we be ready? Addressing these and other questions is David Quammen, author of Spillover: Animal Infections and the Next Human Pandemic. Mr. Quammen's book illuminates the origins and dynamics of Ebola, SARS, bird flu, Lyme disease, and other emerging threats.

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Host: John J. Russell, MD

At the turn of the last century, a powerful smallpox epidemic swept the United States from coast to coast. The age-old disease spread swiftly through an increasingly interconnected American landscape: from southern tobacco plantations to the dense immigrant neighborhoods of northern cities to far-flung villages on the edges of the nascent American empire. In Pox, award-winning historian Michael Willrich offers a gripping chronicle of how the nation's continentwide fight against smallpox launched one of the most important civil liberties struggles of the twentieth century.

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Host: John J. Russell, MD

In his book, The Wildlife of Our Bodies, biologist Rob Dunn from the Department of Biology at North Carolina State University opines that while "clean living" has benefited us in some ways, it has also made us sicker in others. We are trapped in bodies that evolved to deal with the dependable presence of hundreds of other species. As Dunn reveals, our modern disconnect from the web of life has resulted in unprecedented effects that immunologists, evolutionary biologists, psychologists, and other scientists are only beginning to understand.

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Host: John J. Russell, MD

In 1998 Andrew Wakefield, a British gastroenterologist with a history of self-promotion, published a paper with a shocking allegation: the measles-mumps-rubella vaccine might cause autism. The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. Yet despite the numerous studies that failed to find any link between childhood vaccines and autism, it has since been popularized by media personalities, and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. In The Panic Virus: The True Story Behind the Vaccine-Autism Controversy, author Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is?

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Host: John J. Russell, MD

500,000 Americans died over a 6 week period; is this the latest thriller from Hollywood, or a piece of American history? Joining host Dr. John Russell to elaborate is Gina Kolata, acclaimed reporter for The New York Times and author of Flu:The Story Of The Great Influenza Pandemic of 1918 and the Search for the Virus that Caused It. In Flu, Ms. Kolata unravels the mystery of this lethal virus. From Alaska to Norway, from the streets of Hong Kong to the corridors of the White House, Kolata tracks the race to recover the live pathogen and probes the fear that has impelled government policy ever since. A gripping work of science writing, Flu addresses the prospects for a great epidemic's recurrence and considers what can be done to prevent it. 

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Host: Linda Bernstein, Pharm.D.

In this premiere edition of The Pharmacy Report®, host Dr. Linda Bernstein focuses on the growing threat of antimicrobial drug resistance. Top news stories include the CDC's "Threat Report 2013," and FDA drug and new indication approval updates. In this week's Movers and Shakers segment, Joseph Guglielmo, PharmD, Dean of the UCSF School of Pharmacy and a clinical pharmacist specialist in infectious disease will address antimicrobial stewardship and the role of the physician and pharmacist in these multidisciplinary programs.

References mentioned in this segment:

  • Centers for Disease Control and Prevention:
    Threat Report 2013 Antibioitic Resistance Threats in the United States, 2013
  • Antimicrobial stewardship guidelines Dellit TH, Owens RC, McGowan Jr JE, Gerding DN, Weinstein RA, Burke JP, Huskins WC, Paterson DL, Fishman NO, Carpenter CF, Brennan PJ, Billeter M, and Hooton TM. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Guidelines for Developing an Institutional Program to Enhance Antimicrobial Stewardship. Clin Infect Dis. 2007 Jan 15;44(2):159-77
  • IDSA REPORT: Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America Boucher HW, Talbot GH, Bradley JS, Edwards JE, Gilbert D, Rice LB, Scheld M, Spellberg B, …

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Host: John J. Russell, MD

A maddened creature, frothing at the mouth, lunges at an innocent victim and, with a bite, transforms its prey into another raving monster. It's a scenario that underlies our darkest tales of supernatural horror, but its power derives from a very real virus, a deadly scourge known to mankind from our earliest days. In this fascinating exploration, journalist Bill Wasik and veterinarian Monica Murphy speak with host Dr. John Russell about the history, science, and cultural mythology of rabies as described in their book "Rabid."

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Guest: Shelly Batra, MD

Host: Maurice Pickard, MD

Multidrug Resistant (MDR) Tuberculosis is a growing public health epidemic in India. Experts estimate there could easily be over 5 million cases of MDR TB at present, with each untreated patient capable of spreading the disease to 10-15 others per year. The non-profit organization Operation ASHA has expanded its role considerably over the past few years to stem this tide of TB transmission from the poorest to the most prosperous communities, bringing innovative treatment protocols right to the patients' doorsteps. Dr. Shelly Batra, president of Operation ASHA, discusses the progress being made in this increasingly global public health campaign. Hosted by Dr. Maurice Pickard.

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Guest: Shelly Batra, MD

Host: Maurice Pickard, MD

Multidrug Resistant (MDR) Tuberculosis is a growing public health epidemic in India. The non-profit organization Operation ASHA has expanded its role considerably over the past few years to stem this tide of TB transmission within both the poorest and the most prosperous communities, bringing innovative treatment protocols right to the patients' doorsteps. Dr. Shelly Batra, president of Operation ASHA, discusses the progress being made in this increasingly global public health campaign. Hosted by Dr. Maurice Pickard.

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Host: Matt Birnholz, MD

Lyme disease is one of the most rapidly emerging infectious diseases in North America and Europe. In 2009, nearly 30,000 confirmed and more than 8,500 probable cases of Lyme disease were reported to the CDC in the United States alone. Named after a small Connecticut town, Lyme disease is transmitted to humans by the bite of ticks infected with the bacterium Borrelia burgdorferi. This multi-system infection typically occurs in stages with different clinical manifestations at each stage. While it can be treated effectively with antibiotics, in some cases recovery may be incomplete - although there is no evidence that any of these post-Lyme disease syndromes respond to further courses of antibiotic therapy.

Dr. Allen Steere, the renowned discoverer of Lyme disease, joins an esteemed panel of speakers for CDC's Public Health Grand Rounds to explore the clinical manifestations and treatment of Lyme disease, innovations in laboratory testing, prevention strategies, and national trends of disease emergence. The session gives a rare glimpse into the front lines of those battling and treating Lyme disease while addressing the data gaps, unmet needs, and overall challenges and opportunities for its prevention and control.

This is Part 3 of a lecture in three parts.

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Host: Matt Birnholz, MD

Lyme disease is one of the most rapidly emerging infectious diseases in North America and Europe. In 2009, nearly 30,000 confirmed and more than 8,500 probable cases of Lyme disease were reported to the CDC in the United States alone. Named after a small Connecticut town, Lyme disease is transmitted to humans by the bite of ticks infected with the bacterium Borrelia burgdorferi. This multi-system infection typically occurs in stages with different clinical manifestations at each stage. While it can be treated effectively with antibiotics, in some cases recovery may be incomplete - although there is no evidence that any of these post-Lyme disease syndromes respond to further courses of antibiotic therapy.

Dr. Allen Steere, the renowned discoverer of Lyme disease, joins an esteemed panel of speakers for CDC's Public Health Grand Rounds to explore the clinical manifestations and treatment of Lyme disease, innovations in laboratory testing, prevention strategies, and national trends of disease emergence. The session gives a rare glimpse into the front lines of those battling and treating Lyme disease while addressing the data gaps, unmet needs, and overall challenges and opportunities for its prevention and control.

This is Part 2 of a lecture in three parts.

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Host: Mimi Secor, DNP, FNP-BC, FAANP

Guest: Terri Warren, NP

The CDC has recommendations when it comes to the treatment, testing and counseling of patients who may have sexually transmitted infections or at high risk of contracting an STI. There are a number of ways to test for diseases like gonnorhea, chlamidiya, and syphillis and that can be confusing for NPs and their patients. Nurse Practitioner Terri Warren with the Westover Clinic in Portland, Oregon explains to host Mimi Secor some of the most important changes recommended by the CDC to help reduce the number of sexually transmitted infections in the country especially among teens.

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Host: Matt Birnholz, MD

The CDC commemorates Dr. Robert Koch's 1882 discovery of Mycobacterium tuberculosis, the bacteria that causes TB. Over the past 129 years, history has witnessed many advances over in TB control. Through the intervention efforts of CDC, USAID, WHO's Stop TB Partnership, and many others, TB death rates have fallen by 35% since 1990, and as many as 6 million lives have been saved since 1995.

In spite of these successes, TB still remains a serious threat, especially for those infected with HIV. HIV is the single most powerful risk factor for TB disease and one of the leading causes of death among people infected with HIV. Among the 1.7 million lives that TB claimed in 2009, 380,000 were among people with HIV infection. While people with HIV who have TB can be effectively diagnosed and treated, more effort is needed to diagnose and treat TB promptly and effectively, and to scale-up preventive treatment for TB.

This special session of Public Health Grand Rounds shed light on myths and misconceptions about TB and HIV, and discussed actions needed in preventing deaths from this lethal combination.

This is Part 3 of a lecture in three parts.

Part 1 >>

Part …

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Host: Matt Birnholz, MD

The CDC commemorates Dr. Robert Koch's 1882 discovery of Mycobacterium tuberculosis, the bacteria that causes TB. Over the past 129 years, history has witnessed many advances over in TB control. Through the intervention efforts of CDC, USAID, WHO's Stop TB Partnership, and many others, TB death rates have fallen by 35% since 1990, and as many as 6 million lives have been saved since 1995.

But in spite of these successes, TB still remains a serious threat, especially for those infected with HIV— the single most powerful risk factor for TB disease and one of the leading causes of death among people infected with HIV. Among the 1.7 million lives that TB claimed in 2009, 380,000 were among people with HIV infection. While people with HIV who have TB can be effectively diagnosed and treated, more effort is needed to diagnose and treat TB promptly and effectively, and to scale-up preventive treatment for TB.

This special session of Public Health Grand Rounds sheds light on myths and misconceptions about TB and HIV, and discusses actions needed in preventing deaths from this lethal combination.

This is Part 2 of a lecture in three parts.

Part 1 >>

Part …

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Guest: Everett Winslow Lovrien, MD

Host: Matt Birnholz, MD

Host: Michael Greenberg, MD

This week, hosts Drs. Matt Birnholz and Michael Greenberg wrap up 2010 with a look at the year's most notable research; as well as some notably retracted research, with Jef Akst of The Scientist; and talk with Dr. Everett Winslow Lovrien, whose book Doctor Guilt? looks at how thousands of hemophilia patients in the 1970s and 80s came to be treated with HIV-tainted medication. Plus: Just in time for your holiday parties, notable findings on cheese fondue and vodka, gleaned from the pages of the British Medical Journal's Christmas issue.

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Host: Matt Birnholz, MD

The 2010 meeting of the Infectious Diseases Society of America, held in Vancouver, Canada, October 21 - 24, attracted over 47-hundred participants from 82 countries around the world. This year's conference included presentations highlighting advances in a number of important areas — including the development of antibiotics and prevention of antibiotic resistance; HIV management; and both seasonal and H1N1 vaccine uptake and safety.

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Guest: Lynne Mofenson, MD

Host: Maurice Pickard, MD

Although HIV transmission through breast milk is a significant global health issue, many mothers and their babies depend on breastfeeding for survival. About 90% of children who become infected with HIV each year are in sub-Saharan Africa. What therapeutic interventions are recommended for mothers with HIV in order to prevent transmission of the virus to their babies? Dr. Lynne Mofenson, chief of the pediatric, adolescent and maternal AIDS branch at the National Institute of Child Health and Human Development, at the National Institutes of Health in Rockville, Maryland, discusses two exciting new developments found to reduce the risk of HIV transmission from mothers to their babies in places where replacement feeding for infants isn't available. Hosted by Dr. Maurice Pickard.

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Guest: Mark Pendergrast

Host: Matt Birnholz, MD

Host: Michael Greenberg, MD

Hosts Drs. Michael Greenberg and Matt Birnholz interview Mark Pendergrast, author of the new book Inside the Outbreaks: the Elite Medical Detectives of the Epidemic Intelligence Service. The Second Opinion Live hosts also discuss new research on salt, chocolate, and a patient who's opened his case to the Internet and the wisdom of crowds. Plus, can martial arts teach senior citizens how to fall?

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Host: Mark Chyna, MD

Tune in to hear news and research from the Infectious Diseases Society of America's 47th Annual Meeting in Philadelphia.

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Guest: Norman Edelman, MD

Host: Matt Birnholz, MD

Host: Michael Greenberg, MD

We are moving closer to the height of what many feel will be an extraordinarily busy flu season, with H1N1 and the seasonal flu both central parts of the discussion. We don't know exactly how serious H1N1 will be, but we do know that it's here, that many more people could get sick, and that we have to be prepared to deal with it. Hosts Dr. Michael Greenberg and Dr. Matt Birnholz speak with Dr. Norman Edelman, chief medical officer for the American Lung Association and a professor of preventive medicine and internal medicine at the State University of New York at Stony Brook.

Dr. Birnholz and Dr. Greenberg will also give you their take on an amusing recitation of the health reform bill in the House known as HR 3200. They will also play back the winning entry in an entertaining yet informative contest to create a public service announcement on H1N1, co-sponsored by the U.S. Department of Health and Human Services. You won't want to miss it!

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Guest: Abraham Verghese, MD, MACP

Host: Martin Samuels, MD

What does treating a patient with a stigmatized illness teach a physician about treating all illness? Dr. Abraham Verghese, professor for the theory and practice of medicine at Stanford University School of Medicine, joins host Dr. Martin Samuels to discuss the effects of stigmatized medicine on the physician-patient relationship, and other topics.

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Host: Mark Nolan Hill, MD

Guest: Jeffrey Klausner, MD, MPH

Detection and treatment of HIV in the United States has improved dramatically since the peak of the epidemic here in the 1980s, but there is far more work to be done. HIV transmission is one area of heightened concern, particularly those cases spread by newly infected persons who remain undiagnosed. Though tests are available to diagnose HIV in the acute phase, many experts believe we must improve these tests to really make headway in reducing the incidence of HIV in the United States. Dr. Jeffrey Klausner, a deputy health officer and director of the STD Prevention and Control Services Section at the San Francisco Department of Public Health, joins host Dr. Mark Nolan Hill to lay out the path toward progress in detecting acute cases of HIV infection. Newer, more effective tests are available, but must be adopted around the United States, and as Dr. Klausner looks ahead, a point-of-care rapid exam, though still in development, could eventually change the paradigm for early-stage HIV detection.

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Guest: Patrick Schlievert, PhD

Host: Lee Freedman, MD

HIV research has encountered quite a few setbacks, especially with attempts to create an HIV vaccination. But topical microbicides made from glycerol monolaurate, commonly found in some foods and cosmetics, are showing some promise. What mechanisms of microbicides may help successfully prevent infection, including HIV and other sexually transmitted infections? Dr. Patrick Schlievert, professor of microbiology and immunology at the University of Minnesota Medical School, explains the exciting potential of topical microbicides for preventing the transmission of sexually transmitted infections and HIV. How soon might one of these topical microbicides be available, if they are further proved to have efficacy? Dr. Lee Freedman hosts.

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Guest: Joan Nichols, PhD

Host: Michael Greenberg, MD and Larry Kaskel, MD

Events surrounding the spread of H1N1 influenza virus have dominated the news over the course of the last few weeks. We are all receiving calls from patients worried that they may have symptoms, while others are concerned that they may be at risk. Everyone has questions: Is there any need to think about stockpiling Tamiflu and other antiviral products, and should we recommend that at-risk patients start on a prophylactic antiviral regimen? How long will it be until we have vaccine resources at hand to combat the virus? Hosts Dr. Michael Greenberg and Dr. Larry Kaskel sort through your questions, as well as those you are getting from your patients, with the help of Dr. Joan Nichols, associate director of research at the Galveston National Biocontainment Laboratory, our nation's first national biocontainment facility, based in Galveston, Texas. Dr. Nichols, who is also an associate professor of microbiology & immunology at the University of Texas Medical Branch at Galveston, will also explore a few symptoms of the H1N1 virus that may allow us to distinguish the infection from that of the more commonplace seasonal influenza.

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Guest: Michael Gabay, PharmD, JD

Host: Charles Turck, PharmD, BCPS, BCCCP

Culled from human plasma, intravenous immunoglobulin (IVIG) is an expensive and limited resource. These constraints underscore the importance of ensuring that our clinical uses of IVIG are in line with the applications for which we have best demonstrated its efficacy. Yet IVIG has only amassed a short list of FDA-approved indications, and is often employed as an off-label therapy. In what areas is our use of IVIG best supported by the literature, and is this consistent with how the agent is most commonly used? Host Dr. Charles Turck examines these questions and more with Dr. Michael Gabay, clinical assistant professor at the University of Illinois at Chicago College of Pharmacy, where he directs the university's Drug Information Group and Prior Authorization Services.

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Guest: Pride Chigwedere, MD, PhD

Host: Cathleen Margolin, PhD

Dr. Pride Chigwedere, an affiliate of the Harvard AIDS Initiative, speaks with host Dr. Cathleen Margolin about the role of government policy in the AIDS epidemic in South Africa. Dr. Chigwedere's research, as published in the Journal of Acquired Immune Deficiency Syndromes, pins fault on these frightening government rules for the loss of more than 3.8 million person-years in the early portion of this decade. How is South Africa now moving toward a state of accountability for this crucial aspect of their overall public health strategy?

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Guest: Paul Farmer, MD, PhD

Host: Martin Samuels, MD

Aside from pure altruism, is there any reason that an American doctor should care about healthcare elsewhere, particularly in parts of the world remote as Russian jails? Joining host Dr. Martin Samuels is Dr. Paul Farmer, medical anthropologist and founding director of Partners in Health, an international health and social justice organization, to discuss this and other important topics.

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Guest: W. David Hardy, MD

Host: Maurice Pickard, MD

Dr. David Hardy, director of infectious disease at Cedars-Sinai Medical Center in Los Angeles, emphasizes that we already have methods for prevention of the HIV epidemic, especially among gay men and African-Americans. He tells host Dr. Maurice Pickard that, if implemented, the Centers for Disease Control and Prevention's new recommendation for testing, that does away with exceptionism, would go a long way towards diagnosing the 25 percent of cases in the United States that are not identified.

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Guest: W. David Hardy, MD

Host: Maurice Pickard, MD

A new test to differentiate recent from older HIV infections may help experts more accurately track prevention programs. Host Dr. Maurice Pickard is joined by Dr. David Hardy, director of infectious disease at Cedars-Sinai Medical Center in Los Angeles. Dr. Hardy talks about new statistics from the CDC indicating significant increase in the diagnosis of HIV and AIDS in young men and African-Americans.

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Guest: Lorie Chaiten, JD

Host: Lauren Streicher, MD

For the past 25 years, the U.S. government has funded abstinence-only sex education in public schools.  Still, 47 percent of high school students report having had sexual intercourse and 70 percent are sexually active by age 19.  Lorie Chaiten, director of the Reproductive Rights Project for the Roger Baldwin Foundation of the ACLU of Illinois, talks with host Dr. Lauren Streicher about the implications for young people's sexual health when they are denied access to complete and accurate science-based information.

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Guest: Robert Bailey, PhD, MPH

Host: Larry Kaskel, MD

New research reveals that male circumcision could reduce HIV infection rates by up to 60 percent, which could prevent 5.7 million new cases and 3 million deaths over 20 years in sub-Saharan Africa. Dr. Robert Bailey, professor of epidemiology at the University of Illinois, Chicago, School of Public Health, discusses his research findings with host Dr. Larry Kaskel, highlighting HIV infection rates in areas of Africa where the male population is circumcised, and explaining the mechanism by which HIV infection may occur in uncircumcised men.

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Guest: James Crowe, MD

Host: Mark Nolan Hill, MD

Preparing for the future by studying the past: With researchers now able to resurrect antibodies to the 1918 influenza pandemic from elderly survivors, how does the technology used to do this potentially lead us to antibodies for other viruses? Can we be sure this immunity is not generated by recent exposure to similar strains? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, explains how we are beginning to learn more about where viruses, including HIV, are most susceptible to being controlled and destroyed. Dr. Mark Nolan Hill hosts.

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Host: Mark Nolan Hill, MD

Guest: James Crowe, MD

Ninety-plus years after the 1918 influenza pandemic, we are just beginning to understand the naturally occurring adaptive immunity of those who were in contact with this devastating virus. As researchers probe survivors of the flu pandemic, all of whom are approaching or have attained centenarian status, what are we learning about their long-lasting immunity to this virus? Can we explain why these people survived this expansive outbreak, just as relatives and friends around them perished? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, shares some of the tricks that his team has used to make these antibodies in this fascinating discussion with Dr. Mark Nolan Hill.

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Guest: James Crowe, MD

Host: Mark Nolan Hill, MD

First published in 2005, the story of how we've come to understand the complete sequence of the 1918 pandemic influenza virus begins years ago, in a remote Alaskan village, and continues today in research across the country. What are we learning about a virus that has taken many decades to comprehend? Dr. James Crowe, Jr., professor of microbiology and immunology, and director of the Vanderbilt Program for Vaccine Sciences at Vanderbilt University School of Medicine, and one of the researchers leading this expansive project, tells host Dr. Mark Nolan Hill that antibody recognition may actually bear a strong resemblance to cognitive memory. What does Dr. Crowe mean by this? Do we know how the immune system would respond if survivors were infected with this influenza virus?

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Guest: Bruce Walker, MD

Host: Leslie P. Lundt, MD

Chronic viral infections can manifest in two different ways: one group, such as Epstein-Barr virus, are immunologically contained after the acute infection. The other group, including HIV, lead to persistent viremia and progressive clinical disease.  Are there patients who are able to escape the latter without antiviral medications? The director of the Center for AIDS Research at Harvard Medical School, Dr. Bruce Walker, joins host Dr. Leslie Lundt to discuss these so-called "elite controllers."

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Guest: Anthony S. Fauci, MD

Host: Maurice Pickard, MD

Dr. Anthony Fauci, director of National Institute of Allergy and Infectious Diseases at the National Institutes of Health discusses the sentiments and mood after the XVII International Conference on AIDS at Mexico City.  He emphasizes the need for societies and individuals to implement effective and multifaceted treatment and preventive programs, advance human rights, and invest in AIDS and health care systems. Can therapies that are already at our disposal help stop this pandemic? Hosted by Dr. Maurice Pickard.

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Guest: Anthony S. Fauci, MD

Host: Maurice Pickard, MD

Dr. Anthony Fauci, director of National Institute of Allergy and Infectious Diseases at the National Institutes of Health speaks about the daunting challenges 25 years after the discovery of HIV as the pandemic continues to rage worldwide. In particular he describes the factors that have not made it possible to develop a vaccine despite our success in the past with this intervention in other viral illnesses.  Hosted by Dr. Maurice Pickard.

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Guest: Ronald Hall II, PharmD

Host: Charles Turck, PharmD, BCPS, BCCCP

A drug that's been around for decades, vancoymcin is the medicine of choice for treating MRSA infections. While intravenous dosing recommendations are usually weight-based, vancomycin is often prescribed using a flat-dose strategy. Given the growing obesity epidemic in our country, it's worthwhile to ask whether we're underdosing our patients when we write for vancomycin using the conventional flat-dose. Dr. Ronald Hall II joins host Dr. Charles Turck to evaluate vancomycin dosing by weight.

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Guest: Roy Steigbigel, MD

Host: Mark Nolan Hill, MD

We are getting our first in-depth look at some of the research behind raltegravir, a powerful therapy for multi-drug resistant HIV infection already approved by the FDA. How is this raltegravir data impacting current clinical strategies for attacking the virus in multi-drug resistant patients? Host Dr. Mark Nolan Hill probes this question and much more with Dr. Roy Steigbigel, professor of medicine and pathology, molecular genetics and microbiology, and pharmacological sciences, and founding director of the Comprehensive AIDS Center at the State University of New York at Stony Brook.

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Guest: Roy Steigbigel, MD

Host: Mark Nolan Hill, MD

In the quest to find therapies for multi-drug resistant HIV, researchers have zeroed in on raltegravir. The latest data indicates this potent agent provides the highest reported virologic suppression rate among multi-drug resistant patients. Is raltegravir proving more effective than antiretrovirals? Does it carry any prominent side effects? Dr. Roy Steigbigel, professor of medicine and pathology, molecular genetics and microbiology, and pharmacological sciences, and founding director of the Comprehensive AIDS Center at the State University of New York at Stony Brook, details his New England Journal of Medicine research on raltegravir therapy for multi-drug resistant HIV with host Dr. Mark Nolan Hill.

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Guest: Sharon Mitchell, PhD

Host: Michael Greenberg, MD

Dr. Sharon Mitchell joins host Dr. Michael Greenberg to detail her role in addressing healthcare for the adult film industry. Known to many as 'Dr. Mitch,' she describes her own transformation from adult film star to sexual health expert and founder of the Adult Industry Medical (AIM) Healthcare Foundation. She'll also give us an idea of the unique healthcare challenges of caring for adult film workers, and how the AIM Foundation is able to cater to the specific needs of these patients.

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Host: Lee Freedman, MD

Guest: Babatunde Olowokure, MD, MPH, PhD

Guest: Stephen Karpiak, PhD

Rates of STDs in the over-45 population have increased more than twofold since the year 2000. The trend is pushing healthcare providers to stay current on how best to address issues associated with STD care for the older demographic. Host Dr. Lee Freedman learns more from Dr. Babatunde Olowokure, consultant regional epidemiologist from the United Kingdom's Health Protection Agency, and author of research published in the journal Sexually Transmitted Infections, and Dr. Stephen Karpiak, research director for the AIDS Community Research Initiative of America. What's driving this staggering rise in STDs? What initiatives are underway to boost physician awareness of therapeutic measures for our older patients?

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Guest: Stephen Lewis

Host: Cathleen Margolin, PhD

Healthcare professionals are deeply concerned about HIV/AIDS and the problems presented across the world by the disease. Our voices often carry some influence with those leaders in policy and politics who possess the power to do more for the afflicted and to take preventive steps for those at risk, but our intentions must be strong and clear. What specific messages should we be sending to our world leaders and the powers that be? How can we do more to make known our views? Host Dr. Cathleen Margolin investigates these questions on advocacy and more with Stephen Lewis, co-director of AIDS-Free World, a former United Nations special envoy for HIV/AIDS in Africa and a former deputy executive director of UNICEF.

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Guest: Stephen Lewis

Host: Cathleen Margolin, PhD

Women around the world are more likely to be infected with HIV, in part because of their social and economic vulnerability. The stark lack of empowerment of women in many parts of the world indicates the need for men to help protect their gender counterparts from the scourge of HIV. Stephen Lewis, co-director of AIDS-Free World, a former United Nations special envoy for HIV/AIDS in Africa and former deputy executive director of UNICEF, speaks about our need to address the role of sexual violence in furthering the spread of HIV with host Dr. Cathleen Margolin.

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Guest: Stephen Lewis

Host: Cathleen Margolin, PhD

A passionate belief in the power of advocacy fuels AIDS-Free World, an organization working to maintain accountability among those responsible for addressing the challenges of this most devastating disease. Host Dr. Cathleen Margolin speaks with the co-director of AIDS-Free World, Mr. Stephen Lewis, who also is a former United Nations special envoy for HIV/AIDS in Africa and a former deputy executive director of UNICEF.

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Guest: Col. Lisa Keep, MD, MPH

Host: John Armstrong, MD

As our world flattens, we're seeing a similar trend across medicine: developing nations in tropical climates are now increasingly dealing with the lifestyle behavior risks to which we, in the United States, have grown accustomed. Despite this pattern, infectious disease remains a major threat among populations native to the tropics. Host Dr. John Armstrong discusses the current trajectory of tropical medicine, from lifestyle risks, to tuberculosis, malaria and beyond, with Col. Dr. Lisa Keep, director of tropical public health and an assistant professor of preventive medicine at Uniformed Services University of the Health Sciences.

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Guest: Robert Klitzman, MD

Host: Maurice Pickard, MD

HIV is a very preventable disease.  If everyone who is HIV positive agreed not to spread the disease it could be stopped, says our guest, Dr. Robert Klitzman, associate professor of clinical psychology at Columbia University College of Physicians and Surgeons.  Disclosure however is not easy and does not always happen.  Dr. Klitzman explores with host, Dr. Maurice Pickard the size of this non-disclosure problem and why communications are so difficult. It could be that sexual partners are not asking the right questions.

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Guest: Jill Grimes, MD

Host: Jennifer Shu, MD, FAAP

The Centers for Disease Control (CDC) has indicated that 19 million Americans — including one in four teenage girls — are infected with at least one sexually transmitted disease (STD). As physicians, we know that these diseases are far more common than most people think. But are we doing our best to educate our patients and provide appropriate screening measures? How can physicians work to debunk common public misconceptions about STDs? Dr. Jill Grimes, a practicing family physician in Austin, Texas, and author of Seductive Delusions: How Everyday People Catch STDs, addresses a series of erroneous beliefs about STDs and offers counsel on the most effective ways for physicians to help tackle this critical public health problem. Dr. Jennifer Shu hosts.

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Guest: James Welker, DO

Host: Leslie P. Lundt, MD

The time to first antibiotic dose in patients with community-acquired pneumonia is a core quality measure by which hospitals and physicians are evaluated. Might this time pressure have a negative effect on the accuracy of diagnosis of pneumonia? Dr. James Welker, the Director of the Franklin Square Clinical Research Center, joins host Dr. Leslie Lundt to discuss his research in this area.

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Guest: Mark Merchant, PhD

Host: Shira Johnson, MD

Surely the first question you’re asking yourself is, how does one extract blood from an alligator? Mark Merchant, PhD, associate professor of biochemistry at McNeese State University, is one researcher brave enough to tackle this arduous task. Exactly why would Dr. Merchant go this far to get ahold of alligator serum? The answer, indeed, lies in its potentially unique medicinal value. Host Dr. Shira Johnson finds out what features of alligator serum may make it a strong candidate for future use in the clinical setting. The answer may surprise you.

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Host: Shira Johnson, MD

Guest: Mark Merchant, PhD

Dr. Shira Johnson interviews Dr. Mark Merchant on his recent research into the immunity of alligators in their natural habitat. Listen to learn what the implications are for future work with topical products in burn research and more. Why is alligator serum effective against HIV in vitro and is there a take home message for human research in all of this work?

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Guest: Theo Zaoutis, MD

Host: Charles Turck, PharmD, BCPS, BCCCP

Guest: Talene Metjian, PharmD

Antimicrobial stewardship programs (ASP) are recognized as apt measures for effective antimicrobial use and for promoting patient safety in adult care settings. Recent research indicates these programs may be applicable in pediatrics. Theo Zaoutis, MD, and Talene Metjian, PharmD, leaders of the ASP at the Children’s Hospital of Philadelphia, join host Dr. Charles Turck. Can ASPs optimize clinical outcomes related to antimicrobial use?

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Guest: Charles van der Horst, MD

Host: Shira Johnson, MD

Host Dr. Shira Johnson speaks with Dr. Charles van der Horst about his upbringings as an HIV/AIDS specialist and the directions of HIV research today. Dr van der Horst has been involved in HIV research for 27 years and speaks on his concerns within this field along with current trends and funding in 2008. He also talks about his important work in Malawi and South Africa designing and implementing clinical trials for HIV treatment and prevention.

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Guest: Jane Fowler

Host: Gary Kohn, MD

There exists a lingering perception that only certain groups are vulnerable to contracting HIV. Jane Fowler dismisses this notion, and with good reason. Despite eschewing the major risk factors, she contracted HIV in the early 1990s. Now the founder and director of HIV Wisdom for Older Women, Ms. Fowler shares her perspective with host Dr. Gary Kohn. How are we addressing the need to care for older patients contracting and carrying HIV, and is it enough?

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Guest: Jane Fowler

Host: Gary Kohn, MD

As an HIV/AIDS prevention educator, and founder and director for the HIV Wisdom for Older Women Program, Jane Fowler describes her work in educating the public and medical community on the impact of HIV incidence and contraction in seniors with host Dr. Gary Kohn. Tune in and listen to a revealing discussion on the increasing rate of infection of HIV in seniors, including their diagnosis and misdiagnosis.

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Guest: Michael Oxman, MD

Host: Mark Nolan Hill, MD

Guest: William Schaffner, MD

A vaccine for adult shingles was approved by the FDA in 2006 and is in use today. Perversely, recent data shows that delivery of the adult Shingles vaccine has been a challenge. This includes delivery to older populations, on whom the Shingles virus typically realizes its greatest impact. With Baby Boomers nearing the age of greatest risk, how can physicians and other medical professionals improve their dialogue with patients about this vaccine? Host Dr. Mark Nolan Hill examines strategies to improve immunization rates for adult Shingles with Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine at Vanderbilt University School of Medicine.

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Guest: Michael Oxman, MD

Host: Mark Nolan Hill, MD

Guest: William Schaffner, MD

A vaccine for adult Shingles was approved in 2006 by the FDA and is in use today. Yet delivery of this vaccination has not been as widespread as it could and should be. With this in mind, many hospitals and clinics are working to improve on their current approach to its distribution; at some health centers, this includes allowing pharmacists to administer the vaccine. Can this program be implemented nationwide, in accordance with local and state laws? Would this program necessitate any change in insurance coverage for providers? Learn more from Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine at Vanderbilt University School of Medicine. Will this program also lower overall immunization costs? Dr. Mark Nolan Hill hosts.

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Guest: Michael Oxman, MD

Host: Mark Nolan Hill, MD

Guest: William Schaffner, MD

A vaccine for adult Shingles was officially licensed for use in 2006, but recent data shows that delivery of this vaccination has been a challenge. What are some of the issues which are limiting the distribution of the Shingles vaccine? How can we best address these difficulties? For expert insight on these questions and more, host Dr. Mark Nolan Hill welcomes Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine and professor of medicine in the department of infectious diseases at Vanderbilt University School of Medicine.

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Guest: Michael Oxman, MD

Host: Mark Nolan Hill, MD

Guest: William Schaffner, MD

Decades of research have gone into the isolation and refinement of a vaccine for adult shingles, approved in 2006 by the FDA and in use today. Do we now fully understand the mechanism which activates the latent varicella-zoster virus, leading to adult shingles? How did initial isolation, going back more than 30 years, of the vaccine for chicken pox (triggered by the same varicella virus) contribute to the investigations on adult shingles? Host Dr. Mark Nolan Hill discusses these questions and more with Dr. Michael Oxman, professor of medicine and pathology at the University of California, San Diego School of Medicine, and Dr. William Schaffner, professor and chair of preventive medicine and professor of medicine in the department of infectious diseases at Vanderbilt University School of Medicine.

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Guest: Anthony Fiore, MD

Host: Bruce Bloom, DDS, JD

Why has this year's flu season seemed more severe than those in the past? Are the vaccines working? Are influenza strains more difficult to predict? In addressing this year's peculiar flu season, host Dr. Bruce Bloom speaks with Dr. Tony Fiore, a vaccination and immunization expert from the CDC's National Center for Infectious and Respiratory Diseases in Atlanta.

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Guest: Anthony Fiore, MD

Host: Bruce Bloom, DDS, JD

With this year's flu season comes the recommendation from the CDC to extend the age of childhood vaccination past the previous age of 59 months, to 18 years. Why the change, and what are the recommendations based upon? Joining Dr. Bruce Bloom to discuss this year's recommendation is Dr. Anthony Fiore, a vaccination and immunization expert, and medical epidemiologist from the CDC in Atlanta.

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Host: Leslie P. Lundt, MD

Guest: Aine Collier, EdD

“A mysterious epidemic, hitherto unknown, which had struck terror into all hearts by the rapidity of its spread, the ravages it made, and the apparent helplessness of the physicians to cure it.” This 16th century writer was discussing syphilis. Author Aine Collier joins host Dr. Leslie Lundt to explore the history of sexually transmitted disease and the early treatments used to combat them.

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Guest: David Morens, MD

Host: Gary Kohn, MD

Is dengue fever the new West Nile virus? How does it spread? Is there serious potential for an outbreak in the United States? David Morens, senior adviser to the director of the National Institute of Allergy and Infectious Diseases, National Institutes of Health, speaks with host Dr. Gary Kohn on dengue fever's pathogenesis, epidemiology, and potential impact in the United States.

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Guest: Richard Atkinson, MD

Host: Lee Freedman, MD

Dr. Atkinson reviews the animal data, the human observational data and the data on viral mechanisms of action to make the case that a human adenovirus may paly a key role in the development of human obesity. Learn how this information may lead to novel approaches in preventing obesity in humans. Could these efforts save society and individuals from the huge costs of being overweight?

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Guest: Richard Atkinson, MD

Host: Lee Freedman, MD

Are there unseen factors in the worldwide obesity epidemic? Dr. Richard Atkinson, Emeritus Professor of Medicine and Nutritional Sciences at the University of Wisconsin, and editor of the International Journal of Obesity explains the rationale behind an infectious etiology for the worldwide obesity epidemic with your host, Dr. Lee Freedman. He addresses the evidence supporting the theory that viruses may play an important role in the development of obesity in animals and humans.

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Guest: Shelly Batra, MD

Host: Maurice Pickard, MD

Dr. Shelly Batra talks about the reasons she shifted her focus from her private practice as a gynecologist, and a career as a best-selling physician-author and television personality, to fighting tuberculosis in India's urban slums. In India, this disease carries a stigma and, for women, can mean the loss of a job, ostracism from their own family and little hope of being married. Dr. Maurice Pickard hosts.

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Guest: Shelly Batra, MD

Host: Maurice Pickard, MD

Dr. Shelly Batra, a gynecologist, author, and the medical director of the nonprofit Operation Asha, talks with host Dr. Maurice Pickard about her organization's fight against tuberculosis among New Delhi's impoverished and marginalized ragpickers in the urban slums of New Delhi, where adequate nutrition and sanitation are nonexistent. The clinic is staffed by paid employees from the same slums, who counsel patients and keep them coming back to continue their treatment. With donated funds, the clinic also offers incentives like blankets, food, and over-the-counter medicines to encourage patients to complete their treatment.

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Guest: David Kertzer, PhD

Host: Leslie P. Lundt, MD

We all know that sometimes the answers to today’s problems can be found in the past. Our guest today will take us to 19th century Italy where we will have a glimpse into a dark page of social and medical history. At one time, up to 10% of European men had syphilis – its victims were rumored to include Beethoven, Van Gogh, Baudelaire, Oscar Wilde, Flaubert. But the syphilis epidemic had another side that hasn’t gotten much attention. Dr. David Kertzer of Brown University has written a detailed account of how one Italian woman contracted syphilis from an infant. He joins host Dr. Leslie Lundt to discuss his latest book, “Amalia’s Tale”.

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Host: Michael Benson, MD

The CDC has decided to open a file on “Morgellons” a newly described dermopathy. What made them decide to look into this demopathy? How do the disease hunters plan to get to the bottom of this new malady? Our guest today is Dr. Michelle Pearson, an epidemiologist with the Centers for Disease Control in Atlanta. She is heading the effort to look into Morgellons.

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Host: Michael Benson, MD

Morgellons is a disease straight out of "The X-Files." In fact, the government opened a file on it. A newly recognized dermopathy, Morgellons is now receiving scrutiny from the Centers for Disease Control (CDC). Dr. Michelle Pearson, a CDC epidemiologist leading the effort to examine Morgellons, joins host Dr. Michael Benson.

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Guest: Kristin Harper

Host: Paul Raeburn

The first recorded outbreak of syphilis occurred in Naples, Italy in 1495. Controversy has raged over the source of the pathogen, but a recent study suggests that when Columbus discovered the New World, he also discovered syphilis. The evidence comes from an updated treponemal family tree published in PLoS. How did investigators collar Columbus? And how good is their evidence?

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Guest: Michael Otto, PhD

Host: Paul Raeburn

The CDC says it’s killing more people than AIDS, emphysema, or Parkinson’s disease—Can we stop the new strains of Staph aureus bacteria? Our topic today is MRSA. Recently, the Centers for Disease Control and Prevention reported an estimate of 94,000 patients developing MRSA infections in the US over the course of 2005. Of this number, nearly 19,000 people died, a stunning mortality ratio of one in five. Our guest today is Dr. Michael Otto, a microbiologist from the Rocky Mountain Laboratories in Montana, a part of the National Institute of Allergy and Infectious Diseases. In a recent paper in the journal Nature Medicine, Otto and his colleagues say they’ve found what they think is the mechanism that makes MRSA so virulent.

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Guest: Arjun Srinivasan, MD

Host: Shira Johnson, MD

Dr. Shira Johnson interviews Dr. Arjun Srinivasan, who is a Medical Epidemiologist from the CDC in Atlanta. His work is to diagnose and to prevent outbreaks of infections in the hospital and in the community. Learn about a resistant infection caused by Acinetobacter which is prolonging ICU stays across the country. Acinetobacter species has become increasingly difficult to treat due to the development of antibiotic resistance, and mortality and length of hospitalization are increased in a subset of patients.

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Guest: Arjun Srinivasan, MD

Host: Shira Johnson, MD

Join Dr Shira Johnson as she interviews Dr. Arjun Srinivasan, a Medical Epidemiologist from the CDC in Atlanta. His job is to investigate outbreaks of infections in hospitals and communities across the country and importantly, to prevent them from occurring again. Why is resistance spreading from the community to the hospital, and are we responding appropriately? What you don't know about MRSA may surprise you.

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Guest: Arjun Srinivasan, MD

Host: Shira Johnson, MD

Dr. Arjun Srinivasan is a Medical Epidemiologist at the CDC in Atlanta, and his work involves diagnosing and and stopping outbreaks of infectious diseases. Join Dr. Shira Johnson as she interviews him to learn why a virulent strain of the well known MRSA microcrobe is on the rise in the community at this time. Are we effective in our approach to the new epidemic of antibiotic resistance in this organism? And why did it occur?

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Host: Michael Benson, MD

Guest: Susan Cu-Uvin, MD

For women with HIV in the US, nursing is not an option. Yet is nursing their babies a better choice for women with HIV in other countries? The answer may surprise you. Today our guest is Dr. Susan Cu-Uvin, professor of obstetrics and gynecology and Medicine at Brown Medical School. She is also Director of the Miriam Hospital's Immunology Center in Providence Rhode Island, which provides comprehensive care to over a thousand women and men living with HIV/AIDS. She is doing NIH-funded research on the prevalence and transmission of HIV among women during pregnancy.

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Host: Michael Benson, MD

Guest: Susan Cu-Uvin, MD

Before the Hepatitis B vaccine, up to one-third of obstetricians had been infected with Hepatitis B—chiefly from needle sticks or other exposures to bodily fluids. However, our modern day plague, HIV has no vaccine. What are the risks to doctors and nurses from providing care to HIV patients? In this segment host Dr. Michael Benson discusses HIV during pregnancy - the myths and prejudices of both patients and health care providers - with. Guest Dr. Susan Cu-Uvin. Dr. Cu-Uvin is professor of OB/GYN and Medicine at Brown Medical School. She is also Director of the Miriam Hospital's Immunology Center in Providence Rhode Island, which provides comprehensive care to over a thousand women and men living with HIV/AIDS. She is doing NIH funded research on the prevalence and transmission of HIV among during pregnancy.

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Guest: Susan Cu-Uvin, MD

Host: Michael Benson, MD

In one developing Asian country, not a single case of HIV was found among several thousand pregnant women tested. Yet in one African country, a whopping 40% of pregnant women were infected. How can either be true? Why? Today our guest is Dr. Susan Cu-Uvin, professor of obstetrics and gynecology and Medicine at Brown Medical School. She is also Director of the Miriam Hospital's Immunology Center in Providence Rhode Island, which provides comprehensive care to over a thousand women and men living with HIV/AIDS. She is doing NIH funded research on the prevalence and transmission of HIV among during pregnancy.

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Guest: Anthony Busti, PharmD

Host: Larry Kaskel, MD

Dr. Larry Kaskel welcomes Dr. Anthony Busti, clinical lipid specialist, to Lipid Luminations. They will discuss HIV patients with regards to antiretrovirals and dyslipidemia and other special issues in this patient population.

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Host: Larry Kaskel, MD

Guest: Ronald Turner, MD

Join Dr. Ron Turner sharing his knowledge of natural remedies for the common cold. What works? What doesn't? Is there any evidence?

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Guest: Chris Beyrer, MD, MPH

Host: Maurice Pickard, MD

Dr. Maurice Pickard is joined by Dr. Chris Beyrer who discusses the startling finding that for women, the greatest risk for contacting Aids is being married despite being monogamous. Adding great insult to injury, these individuals are often the ones exclusively blamed for "shamefully bringing" this disease into their families.

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Guest: Fitzhugh Mullan, MD

Host: Cathleen Margolin, PhD

Dr. Fitzhugh Mullan of George Washington University discusses the proposed U.S. Global Health Service Corps - a peace corps for health that would work to treat and prevent AIDS in 15 countries.

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Guest: Fitzhugh Mullan, MD

Host: Cathleen Margolin, PhD

Dr. Fitzhugh Mullan of George Washington University discusses the challenge of scale up and task shifting in the face of the HIV epidemic.

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Host: Larry Kaskel, MD

Guest: Elizabeth Tieman, MD

Work-life balance: how many of us can say we have it, let alone come close to having it? Board-certified radiologist Dr. Betsy Tieman is one healthcare professional who can say she achieved work-life balance by leaving private practice where she was working 14 hours a day to take advantage of locum tenens work, which also enabled her to train and compete in triathlons.

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Host: Maurice Pickard, MD

Guest: Thomas Quinn, MD

In this segment, Dr. Quinn addresses the history of HIV/AIDS development in Africa over the past 25 years. The interview then follows with a more modern-day look at circumcision practices being used as methods for reducing STD transmission in Africa.

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Host: Maurice Pickard, MD

Guest: Thomas Quinn, MD

In this segment, Dr. Quinn discusses important milestones in the history of HIV/AIDS within America. He then transitions into the modern era with an analysis of the "End of Exceptionalism" initiative by the CDC to blood test the masses for HIV-screening purposes regardless of individual risk factors.

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Guest: Jay Keystone, MD, MPH

Host: Susan Dolan, RN, JD

Join Dr. Jay Keystone, travel and tropical medicine specialist at Toronto General Hospital in Canada as he offers his best travel advice.

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Guest: Jay Keystone, MD, MPH

Host: Susan Dolan, RN, JD

Studies show that 97% of traveler's will make a food or beverage error within 72 hours of arrival often resulting in a trip being ruined due to illness. Join Dr. Jay Keystone, Travel and Tropical Medicine specialist at Toronto General Hospital in Canada as he offers a crash course in travel medicine.

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Guest: Christopher Plowe, MD, MPH

Host: Michael Benson, MD

In this segment, Dr. Plowe describes the malarial preventive treatments and travel-precautionary strategies applied for patients, including chemoprophylaxis, mosquito abatement methods, and chemical repellants such as DDT and Silent Spring. The interview concludes with an examination of natural immunity to malaria and the question on whether some people who live in endemic areas still need prophylaxis.

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Guest: Christopher Plowe, MD, MPH

Host: Michael Benson, MD

In this segment, Dr. Plowe overviews the diagnostic and therapeutic modalities for malaria, as well as the current states of resistance, comparatively on national vs. global levels. The stark discrepancies in available resources for treatment and prevention become quickly apparent as Dr. Plowe describes personal experiences facing total lack of access to health care in large parts of sub-Saharan Africa.

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Guest: Christopher Plowe, MD, MPH

Host: Michael Benson, MD

In this segment, Dr. Plowe describes the pertinent biological features of malarial infection and the scope of malaria's impact on a global level. Many physicians are surprised to learn that between one and three million people continue to die each year secondary to this disease. The interview revisits familiar concepts such as the parasitic life cycles and types of mosquitoes responsible for transmission, and then follows with clinical pearls on malarial disease course and presenting symptoms.

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Guest: Henry Masur, MD

Host: Michael Benson, MD

Join Dr. Henry Masur, President of the Infections Diseases Society of America as he discusses why bacterial resistance is increasing in the United States, with a particular focus on the problems posed by Methicillin Resistant Staph Aureus.

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Guest: Henry Masur, MD

Host: Michael Benson, MD

The rise of bacterial resistance has always been with us. However, the crisis in new antibiotic development has made this chronic problem an increasing clinical threat. In this discussion, Dr. Henry Masur will focus on the clinical problems patients face as bacterial antibiotic resistance rises.

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Guest: Mardge Cohen, MD

Host: Maurice Pickard, MD

Issues in the care of HIV positive women in the United states and similarities in genocide rape survivors of Rwanda

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Host: Mark Chyna, MD

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Guest: Steven Gordon, MD

Host: Matt Birnholz, MD

Dr. Gordon distinguishes between the different strains of the influenza virus discussing the H5N1.

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Guest: Diljeet Singh, MD

Host: Joel Heller, MD

Dr. Singh discusses the recent activities related to the AIDS epidemic in Rawanda.

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Guest: Kenneth Alexander, MD

Host: Bill Rutenberg, MD

Dr. Kenneth Alexander, Associate Professor of Pediatrics and Chief of the Section of Pediatric Diseases at the University of Chicago discusses concerns about patient resistance to antibiotics.

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Guest: Paul Sax, MD

Host: Shira Johnson, MD

Dr. Paul Sax, Clinical Director of the HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital and Associate Professor of Medicine at Harvard Medical School talks about truths and fallacies about HIV/AIDS.

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Guest: Paul Sax, MD

Host: Shira Johnson, MD

Dr. Paul Sax, Clinical Director of the HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital and Associate Professor of Medicine at Harvard Medical School discusses the changes in patterns and trends in the epidemiology of HIV/AIDS.

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Guest: Paul Sax, MD

Host: Shira Johnson, MD

Dr. Paul Sax, Clinical Director of the HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital and Associate Professor of Medicine at Harvard Medical School joins us to discuss the complications involved in HIV/AIDS treatment and pearls for the Primary Care Provider.

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Guest: Paul Sax, MD

Host: Shira Johnson, MD

Dr. Paul Sax, , Clinical Director of the HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital and Associate Professor of Medicine at Harvard Medical School joins us to talk about treatment and caring for patients infected with HIV.

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Guest: Paul Sax, MD

Host: Shira Johnson, MD

Dr. Paul Sax, Clinical Director of the HIV Program and Division of Infectious Diseases, Brigham and Women's Hospital and Associate Professor at Harvard Medical School discusses the major changes in recommendation by the CDC regarding HIV testing.

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Guest: Michael Sadler, MD

Host: Larry Kaskel, MD

AIDS patients abdominal CT images: The imaging findings tends to follow in the clinical condition.

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Guest: Michael Sadler, MD

Host: Larry Kaskel, MD

Bowel and Hepatobiliary findings on CT Imaging in AIDS patients.

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Guest: Michael Sadler, MD

Host: Larry Kaskel, MD

Multidetector CT Scanning: The newest innovation in CT. Multidetection CT scanning obtains four 'slices' of the body at once, allowing radiologists the ability to pick up smaller abnormalities of the body, which translates to earlier diagnoses.

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Guest: Michael Parmacek, MD

Host: Matt Birnholz, MD

Dr. Parmacek discusses the Human Genome project and how the identification of genes can assist with understanding the risk of heart disease.

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Guest: Miriam Rabkin, MD

Host: Joel Heller, MD

Dr. Rabkin describes the AIDS prevention care and services provided to governments and individuals where resources are limited by ICAP.

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Guest: Orin Levine, PhD

Host: Cathleen Margolin, PhD

Dr. Levine discusses the development, benefits and concerns with administration of the pneumococcal vaccination in specific populations.