BEaTS Research Radio's Podcast: Recent Episodes

BEaTS Research Radio

Each week on BEaTS Research Radio at the University of Ottawa Heart Institute, early-career scientists and investigators deep dive into the ever-changing, rapidly evolving world of Science in one-on-one conversations with some of the planet's most brilliant Scientists, breaking down the science in terms you can understand

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In this episode, we sit down with Bryce, a clinical psychologist and musician whose work crosses the borders of mind and body, science and art, structure and improvisation. From assessing cognitive function in the Epilepsy unit to composing and performing folk-rock and psychedelic music, he explores how perception, embodiment, and shared experience shape both therapy and music. Join us as we dive into Bryce’s reflections on the parallels between music and psychology.

0:00:20 | Welcome to the Podcast
0:01:35 | Can you tell us about your journey?
0:05:59 | Where does that instinctive ability for music come from?
0:07:09 | How do you incorporate these arts into your work/patient care?
0:09:35 | How do you feel AI is shaping psychology? What are your concerns?
0:17:35 | Do you have advice for health professionals who are starting their journey and feeling like they have to leave their art behind?
0:20:02 | Thank you

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In this episode, we sit down with Dr. Madhukar Pai, a physician, researcher, and global health leader whose work has consistently crossed borders of geography, disciplines, and institutions to shape medical education and health equity globally. From his leadership at McGill International TB Centre to his widely read editorials on decolonizing global health, Dr. Pai has pushed the field to rethink how knowledge is shared, who gets to produce it, and how medical education can better serve people everywhere. His work has been widely recognized and his leadership valued in many global spaces. Join us as we explore Dr. Pai’s reflections on the challenges and opportunities of transforming medical education across
countries, fields, and organizations.

0:00:20 | Welcome to the Podcast
0:01:44 | Can you tell us about your journey?
0:06:45 | How is global epistemic violence having an impact on young scholars?
0:10:27 | How would you highlight the inequitities in global medical education?
0:14:34 | Can you talk to us about your paper on being pulled into the "Matrix"?
0:19:05 | Will Global Health survive decolonization? And how do students maintain hope?
0:25:57 | Thank you

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In this episode, we explore the work of Dr. Vishna Devi V Nadarajah, a global leader in health professions education whose career crosses borders of science, pedagogy, and geography. From biomedical research to institutional leadership, her work bridges disciplines, nations, and communities of practice. Prof. Vishna Devi V Nadarajah has transitioned to the role of Deputy Vice Chancellor Academic at IMU University in Kuala Lumpur Malaysia. She was formerly CEO , Provost and Professor at Newcastle University Medicine Malaysia.

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In this episode, we’ll be exploring the work of Dr. Saleem Razack, an innovator in changing discriminatory practices and systems in health education and healthcare. His work exists at the intersection of academic and clinical work - from leadership roles as well as research through/in residency programs to faculty advising. He also strives to bridge the gap between research and the application of research to educational policies in order to achieve social justice.

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In this episode, we sit down with Dr. Lorenzo Madrazo, a General Internist and Clinical Scholar whose journey to medicine was shaped by his deep roots in music and education. We explore his research on resident leadership, physician wellness, and the formation of professional identity in healthcare, as well as how his relationship with the arts shapes his perspective.

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In this episode, we’ll be exploring the work of Dr. Foluso Ishola, an internationally trained physician helping to transform global health and health systems through education, research, and policy. She has unique insights into how systems at various levels, from the local to international, shape health as well as how to navigate these spaces in a way that achieves the intended goals while maintaining stakeholder satisfaction.

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In this episode, we speak with Sheena Doyle, a Master of Science in Nursing student at McGill University and a Labor and Delivery Nurse Clinician. We explore how she uses the arts as a powerful tool for critical reflection and health advocacy. Join us as we discuss her commitment to decolonizing healthcare and advancing ethical, relational models of care through research and community engagement.

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In this episode, co-hosts Sam and Ammi from the University of Ottawa’s TMM program are in conversation with Dr. Kevin Smit, a Pediatric Orthopedic Surgeon and Clinical Researcher at the Children’s Hospital of Eastern Ontario (CHEO).

The conversation centers around Adolescent Idiopathic Scoliosis (AIS), which is an abnormal curvature of the spine with no known cause, and can have a significant impact on the lives of its young patients. Dr. Smit is a part of inspiring new research on a developing treatment that could help preserve patient mobility while correcting the curve, called Vertebral Body Tethering (VBT). Here, we discuss AIS and its impact, as well as what makes VBT a unique and promising treatment.

To read the full study: https://doi.org/10.1007/s43390-022-00578-6
Maksimovic, M. et al. The effect of vertebral body tethering on spine range of motion in adolescent idiopathic scoliosis: A pilot study. Spine Deformity 11, 123–131 (2022).

00:04 Introduction

01:11 | As a clinician and researcher, how do you balance these 2 aspects of your life?

02:20 | How do you explain treatment options to your young patients?

04:49 | How do patient impacts inform your research?

09:44 | Are there risks/complications associated with that surgery and recovery?

11:32 | Does having that shoelace allow the patients more motion?

13:36 | Where do you see this research leading?

14:37 | Thank you!

14:47 Outro & Credits

Music: “Lounging Lads” from the Lofi Phantasy album by DanAndPhilBEATS and Lowave.

Saeid Kholgi (producer), Samantha Kiraly (co-host & writing), Ammi Paul (co-host & post-production), Moumita Dutta (writing & social media production)

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Global challenges like climate change demand urgent action, and chemistry is at the center of these emerging solutions. However, graduates starting chemistry-based careers often leave the classroom unprepared to tackle complex global issues. In this podcast, we speak with Dr. Alison Flynn, Principal Investigator of the Flynn Research Group, about how her team is developing strategies to create more engaging and effective learning experiences for students, including the integration of systems thinking into the curriculum. We explore her educational journey, what inspired her to focus on chemistry education, how systems thinking can be applied in classrooms, her thoughts on AI as an emerging educational tool, and more. We also share insights from Dr. Peter Mahaffy on educational resources available to support instructors.

Learn more: https://www.flynnresearchgroup.com/

00:11 | Introduction
01:23- Dr. Flynn's education background
02:49| Challenges and highlights of researching chemistry education
03:40| What is systems thinking
06:24| How to integrate systems thinking into the classroom
07:32| Comment from Peter Mahaffy on tips for educators
07:50| Challenges in organic chemistry and how to succeed
09:14| Redesigning the UOttawa curriculum
11:10| Artificial Intelligence as a tool
13:20| The future of chemistry education
14:48| Conclusion and closing remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:

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Justin Nguyen (Producer), Sophia Guy (Host), Induja Arulchelvam (Writer), Kathleen Connolly (Social Media Producer)

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In this episode of the BEaTS Research Radio, Annie Xiang from the University of Ottawa sits down with Dr. Marcelo Vazquez, radiobiology section head at the Canadian Nuclear Laboratories. Together, they explore how cosmic and proton radiation affects the human body as astronauts prepare for missions to the Moon, Mars, and beyond. Dr. Vazquez shares his journey from aspiring astronaut to NASA researcher, explains the power of human brain organoids as cutting-edge research models, and highlights how this work will help protect future astronauts.

Learn more: https://space.uwo.ca/people/our-members/vazquez-marcelo/index.html

0:01 | BEaTs and host introduction
0:50 | Introduction by Dr. Vazquez and his scientific journey
4:18 | Overview of Dr. Vazquez's research on radiation biology
5:58 | Summary of a paper published by Dr. Vazquez regarding radiation on brain organoids
6:54 | Reasons for using human brain organoid models
8:57 | Challenges encountered during the research process
11:30 | How Dr. Vazquez's findings can help protect astronauts from space radiation
13:30 | Final takeaways by Dr. Vazquez

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Annie Xiang (Voice), Annie Xiang, Adam Al-Khalili, Kamron Yunusov, Tabassum Howlader (Post-production, Content generation, Producers).

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Ananya Jain from the University of Ottawa interviews Dr Adam Rudner about advances in temperate bacteriophage research. Dr. Rudner is a researcher and associate professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. He also co-leads the Howard Hughes Medical Institute (HHMI) Science Education Alliance-Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) associated bacteriophage discovery lab for students in the Translational and Molecular Medicine Program at the University of Ottawa. In this episode, Dr. Rudner discusses bacteriophage basics, the current state of bacteriophage therapy, and how temperate bacteriophages could be harnessed in the future of bacteriophage therapy. Dr Rudner also highlights novel discoveries in the field of temperate bacteriophage biology by discussing his own lab's discovery of a new lysogeny mechanism and discussing the work of Dr. Alex Hynes, a researcher and associate professor at McMaster University, who discovered temperate phage antibiotic synergy (tPAS).

Learn more: https://www.uottawa.ca/faculty-medicine/directory/dr-adam-rudner

0:00 | Introduction to the Podcast
0:29 | Introduction to Dr. Adam Rudner
1:16 | What inspired Dr. Rudner to pursue bacteriophage research
2:23 | The differences between lytic and lysogenic bacteriophages
3:26 | The importance of researching bacteriophages and their therapeutic potential
4:57 | Discussing the work of Dr. Alex Hynes and his discovery of temperate phage antibiotic synergy (tPAS)
7:12 | Advancements required to implement temperate phages and tPAS in therapeutics
8:25 | The discovery of a novel lysogeny mechanism by Dr. Rudner's lab
13:50 | Key Takeaways
14:27 | Concluding Remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Ananya Jain (Host), Rebecca Santhosh Babu (Writer), Mirabel Joseph (Social Media Coordinator), Amber Morton (Producer)

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Jack Cowan from the University of Ottawa interviews Dr. Morgan Fullerton, a Professor in the Department of Biochemistry, Microbiology and Immunology, on behalf of his team in the TMM4950 Science Communication course. Dr. Fullerton discusses dysregulated cholesterol metabolism, a hallmark of atherosclerotic cardiovascular diseases. He delves into his lab’s recent study examining whether AMPK, the cell’s energy sensor, truly protects against atherosclerosis by limiting cholesterol production, where his team made an unexpected discovery that challenged long-standing assumptions in cardiovascular research.

Learn more: https://www.fullertonlab.com/

0:00 | Introduction

1:34 | Introduction of guest (Dr. Morgan Fullerton)

2:35 | What is atherosclerosis?

4:05 | The cell's energy sensor (AMPK)

5:25 | Targeting AMPK|HMGCR to protect against atherosclerosis

7:42 | What was expected when AMPK's control was removed?

8:32 | Importance of validating a disease model

10:25 | Does removing AMPK change atherosclerosis?

12:53 | Future therapies

13:52 | Commentary (provided by Dr. Emily Day) and conclusion

Music is non-copyrighted and free for use.

Jack Cowan (Host), Toshka Besharah (Writer), Melissa Barnett (Producer)

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In this episode, TMM students discuss the hidden declines in long-term care, drawing on insights from Dr. Daniel Kobewka, Dr. Sandy Shamon, and Dr. Susan Mitchell. Through examining changes in mental and physical function, the study highlights how this knowledge can guide more informed, dignity-focused decisions for residents and their families.

Learn more: 10.1001/jamanetworkopen.2025.5635

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Katie Klein (Producer), Sarah Rehmani (Show Host), Paniz Akbari (Social Media Editor), Charlie Levine (Writer Editor)

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Ryan Tu from the University of Ottawa interviews Dr. Sangeeta Murugkar. Dr. Murugkar is an associate professor in the department of medical physics at Carleton University, where she established the Laboratory for Laser-Assisted Medical Physics and Engineering (LLAMPE). In this episode, Dr. Murugkar discusses her recent research in using the non-invasive imaging technique of Raman scattering microscopy to better understand the chemical changes that occur in breast cancer cells.

Learn more: https://lampe.physics.carleton.ca/people/

00:07 | BEaTS and host introduction
00:30 | Introduction to Dr. Murugkar
01:01 | Optical imaging techniques and ongoing research in this field
04:33 | Using Raman scattering microscopy to observe chemical changes in breast cancer
08:48 | Clinical applications of Raman scattering microscopy
14:08 | Conclusion

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Ryan Tu (voice), Abdelrahman Fahmy, Mason Gillick, Raghav Bhargava (post-production, content generation, producers)

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In this episode, James Humber, a Translational and Molecular Medicine student from the University of Ottawa, interviews Dr. Simon Hatcher on behalf of his team for the TMM 4950 Science Communication course. Dr. Hatcher is a psychiatrist at the Ottawa Hospital and Medical Director of Psychiatry at Ottawa Inner City Health. He’s also a scientist at the Ottawa Hospital Research Institute and a professor and Chair of the Department of Psychiatry at the University of Ottawa. His research focuses on suicide prevention and managing the effects of trauma. Together, they address the factors surrounding public safety personnel suicides in Ontario, the contributing stressors, and how policies can change to ensure better mental health care. Special thanks to Dr. Nicholas Carleton, a professor of clinical psychology and registered clinical psychologist in Saskatchewan, who contributed to the making of this episode.

Learn more: https://hatchingideaslab.com/research
https://ptsslab.ca/

2:18 | Introducing our guest: Dr. Simon Hatcher
4:22 | Rethinking resilience in public safety personnel (PSP)
5:12 | Discussion of findings from his recent (2024) paper
7:40 | Exploring Dr. Nick Carleton’s insights
14:28 | Looking ahead: A message of hope
15:24 | Closing remarks

Perfect Storm - Kara Square and Piero Peluche by Piero Peluche (c) copyright 2020 Licensed under a Creative Commons Attribution Noncommercial (3.0) license. https://dig.ccmixter.org/files/pieropeluche/61852 Ft: Kara Square

James Humber (Host), Angélique Cayer (Producer), and Mélodie Bellefleur (Writer)

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Mattea Abou Faiçal from the University of Ottawa interviews Dr. Marisa Azad. Dr. Marisa Azad is an Associate Clinical Scientist at the Ottawa Hospital Research Institute, and a Mayo Clinic Research Collaborator. She is also an Assistant Professor of Medicine in the Division of Infectious Diseases at The Ottawa Hospital. In this episode, Dr. Marisa Azad shares her research on phage therapy and how her team delivered Canada’s first treatment for a multidrug-resistant joint infection.

Learn more: https://www.uottawa.ca/faculty-medicine/directory/dr-marisa-azad

0:04 | BEaTS and host introduction.
1:11 | Introduction to Dr. Azad.
1:45 | Why are periprosthetic joint infections so difficult to treat?
3:30 | Introduction to phages, phage therapy, and a landmark Canadian case study
6:26 | Finding the right phage: collaboration between Cytophage Technologies and The Ottawa Hospital
9:45 | Ethical and regulatory hurdles
12:00 | The growing potential of phage therapy and its current limitations
14:15 | Closing remarks and credits

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Abhijit Sinha (Content Generation), Mattheo Fakhouri (Producer), Mattea Abou Faiçal (Voice) and Jean-Paul Azzi (Post-production)

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Katya Krykunova from the University of Ottawa interviews Dr. Marisa Azad from The Ottawa Hospital about the first use of phage therapy in Canada. Dr. Azad's patient developed a life-threatening periprosthetic joint infection (PJI) of her hip implant. She was allergic to most major antibiotics; the culprit bacteria were resistant to all others, and further surgery would risk her life. All conventional treatments were exhausted. With the patient’s condition declining, Dr. Azad decided to team up with Cytophage Technologies and pursue phage therapy as a last resort. In this episode, Dr. Azad walks us through this clinical case and highlights how phage therapy offers an alternative approach for targeting infections when antibiotics and surgery fail.

Learn more: https://www.mdpi.com/1999-4915/17/8/1118

0:04 | BEaTS and host introduction

0:20 | What is phage therapy?

0:56 | Introduction to Dr. Marisa Azad

2:52 | What are PJIs?

4:26 | Using phage therapy for a severe case of PJI

7:29 | Making phage therapy possible for this patient in collaboration with Cytophage Technologies

9:27 | Ensuring the safety and efficacy of phage therapy

11:31 | What Dr. Azad has learned throughout the process

13:07 | Science, medicine, and art

14:08 | Concluding remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Show Host: Katya Krykunova
Producer: Meghan Walsh
Writer: Sydney Brown, Katya Krykunova
Content generation: Talia LoFaro, Meghan Walsh, Katya Krykunova
Editor: Meghan Walsh, Katya Krykunova, Sydney Brown, Talia LoFaro
Audio post-production: Sydney Brown
Social media coordinator: Talia LoFaro

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Chris Kachi from the University of Ottawa interviews Dr. May Griffith and Andrés Mercado as part of the TMM4950 Science Communication course, exploring cutting-edge advances in bioengineered corneal regeneration. Dr. Griffith is a senior scientist at the Ottawa Hospital Research Institute and a professor in the Faculty of Medicine whose work focuses on regenerative biomaterials and translational ophthalmology. Andrés Mercado is a PhD student in Dr. Emilio Alarcón’s laboratory at the University of Ottawa Heart Institute, developing tunable photo-sealants and customized biomaterials for ocular and soft-tissue repair.

In this episode, they discuss the development of the Cornea-in-a-Syringe (CIS) hydrogel, how regenerative biomaterials such as GF19-functionalized matrices can be tailored to promote ocular healing, and the future of minimally invasive technologies for corneal repair and vision restoration.

Learn more:
Dr. May Griffith - https://www.griffithresearch.ca/may-griffith-2
Andrés Mercado (Alarcón Lab) - https://www.beatsresearch.com/Alarcon.php

0:00 | BEaTS and host introduction.
0:27 | Introduction to Dr. Griffith.
1:11 | Childhood encounter in Malaysia that inspired Dr. Griffith’s mission.
2:57 | Main obstacles to corneal care in low-resource countries.
4:15 | Donor shortages and compatibility challenges in corneal transplants.
5:08 | Why donor compatibility matters and why people hesitate to donate.
5:44 | How artificial/cell-free corneas work - “Field of Dreams” analogy.
7:35 | What is Cornea-in-a-Syringe and how does it expand access?
9:10 | Why combine Cornea-in-a-Syringe with antiviral GF19 instead of just eye drops?
11:44 | Future of corneal treatments and a “vaccine-like” vision restoration.
13:10 | Comments from Andrés Mercado on Dr. Griffith’s work.
14:01 | Podcast conclusion.

Background music: “Podcast Background Music While Talking Interviews - Free Music to use, No Copyright” by Copyright Free Music - Background Music For Videos.
Licensed under Creative Commons Attribution 3.0 (CC BY 3.0).
Watch/listen: https://www.youtube.com/watch?v=cdFqvdekuvI
Channel: https://www.youtube.com/@podcastbackgroundmusic
Creative Commons - Attribution 3.0 Unported - CC BY 3.0
Music promoted by Copyright Free Music - Background Music For Videos - https://www.youtube.com/@podcastbackgroundmusic

Alyssa Thomas (Content Generation), Michael Wossen (Producer), Chris Kachi (Voice), and Salah Hussein Aly (Post-Production)

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Juliet Cruz and Maria Nikokavoura from the University of Ottawa interview Dr. Giovanni Ferrari for the TMM4950 Science Communication course about pushing the limits of donor heart preservation times. Dr. Ferrari is an associate professor of surgical sciences and the Scientific director of the cardiothoracic research program at Columbia University. Dr. Ferrari's research focuses on exploring how the heart functions and how we can better protect it, especially during surgery and organ transplantation. In this episode, Dr. Ferrari presents his findings from their work on a revolutionary method to keep donor hearts viable for up to 48 hours outside the body using a novel oxygen-rich cooling system. This could dramatically expand access to life-saving transplants and reshape how we think about organ preservation.

Learn more: https://columbiasurgery.org/about/giovanni-ferrari-phd

0:00 | Introduction to podcast
0:18 | Introduction to Dr. Ferrari
1:11 | What sparked Dr. Ferrari’s early interest in the heart and organ preservation?
2:59 | What is the HOPE system, and how does it differ from standard cold storage?
5:32 | Why push the limits of donor heart preservation, and what challenges came with it?
6:44 | What surprising insights emerged from the RNA and metabolomic analyses?
9:15 | How did it feel to see a HOPE-preserved heart beat again after 48 hours?
11:15 | Can HOPE principles be applied to preserve other organs in transplantation?
12:09 | What future research questions is the team most excited to pursue?
14:30 | What advice does Dr. Ferrari have for young scientists bridging engineering and medicine?
15:27 | Closing remarks

“Only You with the Universe” by Spøq, licensed via Tribe of Noise PRO. All rights reserved. Listen more:
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Juliet Cruz and Maria Nikokavoura (Voice), Reena Corbane (Post-Production), Nika Abedian (Producer)

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As part of the TMM4950 Sci-Comm special episode, J.P. Doyle from the University of Ottawa interviews Dr. Alexandre Stewart, a distinguished scientist from the University of Ottawa Heart Institute and a director of the Laboratory of Translational Genomics. In this episode, Dr. Stewart and J.P. discuss the viral origins of breast cancer, specifically the hypothesis that the Mouse Mammary Tumor Virus (MMTV) may cause breast cancer in humans. They explored the "second hit" hypothesis, geographic variations in cancer incidence between Western and Eastern Europe, and the potential for future vaccines and anti-retroviral therapies to prevent and treat the disease.

Learn more about Dr. Stewart: https://www.ottawaheart.ca/profile/stewart-alexandre

Read more about the paper: https://doi.org/10.3390/v14030559

0:10 - Introduction to Dr. Alexandre Stewart and Breast Cancer
1:04 - Inspiration: The Biology of Breast Cancer and Immunosuppression
2:48 - Geographic Variation and the Migrant Effect
4:25 - Mechanisms: How MMTV and Human Papillomavirus (HPV) differ in causing cancer
7:05 - The Senegal Study: Globalization and Mouse Populations
10:22 - Vaccines and Anti-Retroviral Parallels
14:34 - Conclusion

Music Credit: This podcast episode features the song 'Documentary' by SigmaMusicArt (Mikhail Smusev) via Pixabay, available under the Pixabay Content License. Listen more:
https://pixabay.com/music/modern-classical-documentary-264400/

J.P. Doyle (Host, Content Writer), Barry Ngo (Producer, Editor, Promoter)

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Listen to this University of Ottawa TMM student discuss 3D testis bioprinting with distinguished guest Dr. Stephanie Willerth. The episode provides an exciting peek into how bioprinting technologies are reshaping reproductive biology research.

Learn more: https://bme.ubc.ca/?directory=stephanie-willerth

1:00 | Early Life, Education, and Journey into Research
2:45 | Exploring the Shift to Reproductive Bioprinting
5:20 | Overcoming Challenges
8:10 | Microsphere Stability and Reproducibility
10:00 | Potential Applications of Microspheres
10:45 | Progress Toward an In-Vivo Model for Full Human Spermatogenesis
12:50 | Advice for Young Scientists

Soundrack

Step Into The Light by Zenboy1955

http://mixter.plus/myTracks.php?id=70336

Catherine Waghorn (Producer), Mathieu D'Souza (Host), Bayan Abou Mehrem (Social Media), Grace Stocker (Editor)

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Emily Wu from the University of Ottawa interviews Dr. Emilio Alarcón on the significance of sex differences in cardiovascular research. Dr. Alarcón is a professor at the University of Ottawa and a scientist at the Heart Institute whose research focuses on developing biomaterials for the regeneration of damaged tissues. In this episode, Dr. Alarcón comments on segments from a previous BEaTS interview between University of Ottawa student Deyanira Hernandez and Dr. Brian Aguado. Dr. Aguado is a professor at the University of California, San Diego, whose research focuses on using biomaterials to determine sex-specific mechanisms of heart diseases, namely aortic valve stenosis (AVS). This episode discusses the effects and significance of including sex differences in disease and biomaterial research.

Learn more:
Dr. Emilio Alarcón - https://www.uottawa.ca/faculty-medicine/dr-emilio-alarcon

Dr. Brian Aguado - https://jacobsschool.ucsd.edu/people/profile/brian-aguado

0:03 | Topic introduction.
1:06 | BEaTS and host introduction.
1:28 | Introduction to Dr. Alarcón.
2:14 | Introduction to Dr. Aguado.
2:58 | The importance of studying biological sex in disease research (Dr. Aguado).
5:13 | The relevance of studying biological sex in biomaterial research (Dr. Alarcón).
7:40 | Precision medicine and sex-based research (Dr. Aguado).
9:07 | Addressing the potential unavailability of precision medicine (Dr. Alarcón).
11:08 | Considering other biological variables in future research (Dr. Alarcón).
14:22 | Concluding remarks.

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Isra Omar (Producer, Post-production, Content generation), Bushra Pathan (Social media editor, Content generation), Malik Thomas (Writer, Content generation), Emily Wu (Host, Content generation).

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In this episode titled “Lost in Translation”, we dive into the complex world of bringing cell therapies from the lab to human trials. With our guest Matthew Jeffers, author of a recent scoping review on this topic, we explore what regulators look for in promising cell therapies and why inconsistent guidelines can leave researchers unsure of their next steps. By summarizing expectations from various regulatory agencies worldwide, Jeffers et. al’s study offers a clearer blueprint for preclinical research, helping innovative treatments reach patients faster.

Learn more: https://ca.linkedin.com/in/msjeffers

0:05 | Introduction
0:46 | Guest introduction
1:24 | Why should we research the regulatory application process?
3:05 | Reasons for the limited coordination between regulators, despite the existence of international health agencies.
5:50 | How regulatory systems shift during exceptional circumstances, such as the COVID-19 pandemic, and the lessons that can be applied to improve the translation of future therapies.
9:34 | The importance of placing a greater emphasis on understanding the regulatory landscape as scientific researchers and students.
12:00 | Episode summary

Background music "Embrace" by Evgeny_Bardyuzha, free for use under Pixabay's Content License.
https://pixabay.com/music/electronic-embrace-364091/

Hosts: Nicholas Lafond and Seb Parmasad
Post-production & Content generation: Chloé McAllister, Mila Schaffrath, Nicholas Lafond, and Seb Parmasad

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Puksar Kunwar, a student from the University of Ottawa, interviews Dr. Marcelo Muñoz for the TMM4950 Science Communication course, focusing on his work developing miniaturized devices for the on-the-spot generation of small-diameter vascular grafts. Dr. Muñoz is an early-career researcher at the University of Ottawa Heart Institute, specializing in clinical peptide therapeutics, biomaterials innovation, and biomedical device design. He was recognized as the top graduating pharmacist in Chile by the National Pharmacy Association. His research aims to “print” new blood vessels inside the human body using a catheter during minimally invasive procedures, and potentially eliminating the need for open-chest surgery.

Learn more: https://advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202500077

0:09 | Introduction to Podcast
0:35 | Introduction to Dr. Muñoz
2:10 | Relevance of Cardiovascular Diseases and Story behind the Discovery of the Device
4:05 | Brief Description of the Device
6:16 | Progress in Clinical Trials with reference to TAVI (Transcatheter Aortic Valve Implantation)
9:30 | Advice for Future Scientists
13:18 | Closing Remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Bhavya Joshi (Post-production & Content generation), Cynthia Chahine (Post-production &Producer), Puskar Kunwar (Show Host), Ezechiel Sugr-Noma Yameogo (Social Media Editor)

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In this episode, we’ll be exploring the work of Dr. Jesse Bump, whose research brings a historical and political economy lens to some of the most pressing challenges in global health. Drawing on history, social science, and policy analysis, Dr. Bump’s research spans local and global scales, offering insight into how societies understand and manage threats to public health.

Learn more about Dr. Thirusha Naidu

https://www.uottawa.ca/faculty-medicine/directory/dr-thirusha-naidu

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In this episode, we’ll be exploring the work of Dr. Jaswant Guzder, an internationally renowned transcultural psychiatrist, psychoanalyst, and visual artist. Our conversation will touch on her work at the intersection of child psychiatry, culture, and community-based mental health, drawing from her leadership roles in Montreal and Victoria, as well as her research and teaching projects in Jamaica and India. We’ll also reflect on how her South Asian heritage, artistic practice, and decades of clinical and academic experience shape her approach to healing, pedagogy, and global mental health.

Learn more about Dr. Thirusha Naidu

https://www.uottawa.ca/faculty-medicine/directory/dr-thirusha-naidu

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In this episode, we’ll be delving into the work of Professor Jennifer Cleland, a global leader whose work continues to challenge and expand the boundaries of healthcare education. Her work crosses boundaries in numerous ways, across fields (Health Economics, Medical Statistics, Language and Linguistics and Business), methodologies (big data sets and qualitative), institutions (government, universities), etc.

Learn more about Dr. Thirusha Naidu

https://www.uottawa.ca/faculty-medicine/directory/dr-thirusha-naidu

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Summary of Podcast Episode: In this episode we delve into Professor Ahmed's research and work at the intersection of medicine, global health, and education policy. Our conversation will focus on the role of power, politics, and inequities in shaping these fields. Together, we’ll explore how critical, and often uncomfortable, conversations can be fostered in ways that are constructive and innovative.

Learn more about Dr. Thirusha Naidu

https://www.uottawa.ca/faculty-medicine/directory/dr-thirusha-naidu

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In this episode, we’ll be exploring the work of Dr. Rashmi Kusurkar, a leading scholar in health professions education whose research centers on the question: how do we develop “students for life”? Her work exists at the intersection of motivation theory, equity, and professional identity, spanning borders, disciplines, and cultures — from advancing Self-Determination Theory in education to addressing access, diversity, and inclusion in healthcare training.

Learn more about Dr. Thirusha Naidu

https://www.uottawa.ca/faculty-medicine/directory/dr-thirusha-naidu

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In this episode, Dr. Brian Aguado discusses the importance of incorporating sex differences research in cardiovascular science, emphasizing how biological variables influence disease progression and treatment outcomes. He highlights that recognizing these differences is key to designing biomaterials with improved performance and inclusivity, ultimately contributing to more effective and equitable healthcare solutions.

Learn more: https://jacobsschool.ucsd.edu/people/profile/brian-aguado

Time stamps

2:20. Why is it important to study sex as a biological variable in this context, and how has it changed the way we understand disease?
6:40 One of the major challenges in biomedical research is designing experiments that truly reflect sex differences. What have been some of the biggest obstacles you have encountered in your work?
10.:20 How do you envision your work on sex-specific biomaterials contributing to more personalized or equitable cardiovascular therapies in the future?
14:02 For young scientists listening to this podcast, what advice would you give to someone interested in integrating sex differences into their own research?

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, Nicolás Alessandroni parle du rôle de la science ouverte dans le cadre des principes IDEAS. Avec lui, nous examinons comment ces principes contribuent à rendre le processus de recherche plus accessible et inclusif – de la production des connaissances à leur application. Nous nous demandons également à qui et dans quelle mesure la science est ouverte et nous nous penchons sur les défis et les responsabilités associés aux processus de recherche réellement ouverts. M. Alessandroni insiste sur l’importance d’étendre les principes IDEAS non seulement à l’accès à l’information, mais aussi à la production même du savoir. L’épisode vous amènera à repenser la notion d’ouverture en sciences et à réfléchir à la mise en place de stratégies visant à rendre les écosystèmes de recherche plus inclusifs.

In this episode, we speak with Dr. Nicolas Alessandroni about the role of open science within the framework of IDEAS. The conversation centers on how IDEAS works to make research processes more accessible and inclusive, from the generation of knowledge to its implementation. We reflect on the guiding question “Open to whom, and to what extent?” and explore the challenges and responsibilities involved in truly open research. Dr. Alessandroni emphasizes the importance of considering not just access to information, but also who participates in knowledge production. This episode invites listeners to rethink what openness means in science today and how we might begin to incorporate strategies to move toward more inclusive research ecosystems.

Learn more: https://www.concordia.ca/faculty/nicolas-alessandroni.html

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, Ulrich Aivodji nous propose une incursion dans son champ de recherche : les principes de l’IA responsable. Il aborde également l’importance d’intégrer à la société des systèmes qui assurent l’équité, la protection de la vie privée et la transparence. Selon lui, l’IA doit être conçue pour éviter la discrimination et les disparités. Il insiste aussi sur le fait que les processus décisionnels doivent être inclusifs et équitables. M. Aivodji fait également remarquer l’importance de former des équipes diversifiées pour générer de nouvelles idées, mais surtout pour favoriser le sentiment d’appartenance et la participation de tout le monde. Selon lui, la conception inclusive et la diversité des points de vue sont les clés pour créer des systèmes plus accessibles, représentatifs et efficaces.

In this episode, Dr. Ulrich shares with us about his research interest in the principles of responsible AI and the importance of integrating systems into society that uphold fairness, privacy, and transparency. He discusses how AI must be designed to avoid discrimination and disparity, emphasizing the need for inclusive, equitable decision-making. Dr. Ulrich also highlights the critical role of diversity in teams, not only to generate more ideas, but to ensure everyone feels they belong and have a right to participate. Through inclusive design and diverse perspectives, we can build systems that are more accessible, representative, and impactful for all.

Learn more: https://aivodji.github.io

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, Stephen Lewis nous parle de son approche du dépistage et du traitement des problèmes de santé mentale, axée sur la personne et son expérience de vie. Il insiste sur l’importance de reconnaître les enjeux systémiques, de lutter contre la stigmatisation et de créer des espaces propices au soutien, à la résilience et au bien-être. M. Lewis prône des pratiques de recherche inclusives qui sollicitent la participation active des personnes directement touchées à toutes les étapes du projet. Il fait aussi remarquer qu’une même situation n’a pas le même effet chez tout le monde, et qu’il est donc essentiel de poser les bonnes questions pour obtenir des travaux de recherche équitables, représentatifs et significatifs.

In this episode, Dr. Lewis discusses their work on identifying and addressing mental health adversities through a person-centred lens grounded in lived experience. He highlights the importance of understanding systemic issues, combating stigma, and creating space for support, resilience, and well-being. Dr. Lewis advocates for inclusive research practices where individuals with lived experience are not only participants but also collaborators and researchers throughout the entire process. Dr. Lewis also emphasizes that even within similar circumstances, each person’s experience is unique, and that asking the right questions is essential to achieving more equitable, representative, and meaningful research.

Learn more: https://www.uoguelph.ca/psychology/users/stephen-p-lewis

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, Nafissa Ismail aborde l’application des principes IDEAS en recherche, particulièrement en sciences fondamentales et cliniques. Elle explique en quoi le manque d’inclusivité dans les études a entraîné des lacunes – toujours présentes aujourd’hui – dans nos connaissances sur la santé des femmes, les symptômes et les maladies les touchant étant souvent mal compris ou carrément ignorés. Elle estime que, même si la situation s’est améliorée, nous devons collectivement en faire bien plus encore. Nous discutons aussi de la nécessité de l’inclusion non seulement à des fins de validité scientifique, mais d’équité en santé également.

In this episode, Dr. Nafissa Ismail discusses how the principles of IDEAS apply from a research perspective, particularly in the context of basic and clinical science. She examines how the lack of inclusivity in study designs has led to a persistent knowledge gap in women’s health, with many symptoms and conditions either misrepresented or overlooked altogether. While progress has been made, Dr. Ismail emphasizes that much more collective effort is needed. Through this conversation, we explore how inclusion is essential not only for scientific accuracy, but also for health equity.

Learn more: https://www.linkedin.com/in/nafissa-ismail-890aa899/?originalSubdomain=ca

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, Dre Carla Rice nous parle de l’importance des activités de recherche qui intègrent véritablement les principes IDEAS, des différences qui émergent lorsque le monde change et de la nécessité de composer avec cette réalité complexe, autant en recherche que dans la société. Selon elle, le progrès technologique, qui vise souvent à améliorer l’accessibilité, peut paradoxalement entraîner de nouvelles formes d’exclusion – une réalité qui montre que l’inclusion n’est pas un objectif figé, mais plutôt un processus continu d’apprentissage et d’adaptation. Nous discutons aussi de la façon dont la peur de l’inconnu et de la différence façonne nos sociétés, et de la manière dont les principes IDEAS appliqués à la recherche peuvent servir d’antidote et favoriser l’inclusion.

In this episode, we talk with Dr. Carla Rice about the importance of research that truly reflects the values of IDEAS and discuss how differences are always emerging as the world changes, and why embracing that complexity is essential in both research and society. She shares her perspective on how technological advancements, while often intended to enhance accessibility, can also unintentionally create new forms of disability, reminding us that inclusion is not a static goal, but a continuous process of learning and adaptation. We also reflect on how fear of difference and the unfamiliar can shape our social systems, and how research rooted in IDEAS can help challenge these responses and build a more inclusive environment.

Learn more: https://family.uoguelph.ca/people/carla-rice

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Le 6 mai 2025, l’Interconnectome cœur-cerveau (ICC) a tenu à l’Université d’Ottawa (Canada) un atelier portant sur les principes IDEAS et la gouvernance des données dans la recherche sur la connexion cœur-cerveau. Les conférencières, conférenciers et scientifiques invités ont accepté de participer au balado BEaTS pour discuter de leur perspective et de leur expérience en répondant à trois questions sur les principes IDEAS (inclusion, diversité, équité, accessibilité et justice sociale) dans la recherche cœur-cerveau.

On May 6th, 2025, the Brain-Heart Interconnectome (BHI) held a workshop, “Brain-Heart Health for All: IDEAS in Data Governance” at the University of Ottawa, Canada. Invited speakers and scientists agreed to participate in the BEATs podcast to share their perspectives and experiences based on three key questions related to IDEAS (inclusion, diversity, equity, accessibility and social justice) in brain (B)-heart (H) research.

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Dans cet épisode, la Dre May Griffith explique à quoi ressemble la mise en pratique au quotidien des principes IDEAS en laboratoire. En s’appuyant sur son riche parcours à l’international, elle soutient que les équipes formées de personnes de divers horizons et aux points de vue différents permettent une meilleure créativité, une plus grande collaboration et des résultats de recherche porteurs. Elle souligne l’importance de réunir non seulement des étudiantes et étudiants de disciplines et de cultures variées, mais aussi des patientes et patients partenaires, dont le vécu apporte une perspective essentielle au processus de recherche. Elle discute également des approches multinationales et multidisciplinaires, lesquelles ont contribué à son succès professionnel, particulièrement dans la science translationnelle.

In this episode, we speak with Dr. May Griffith about what IDEAS looks like in day-to-day lab practice. Drawing from her extensive international experience, Dr. Griffith reflects on how cultivating diverse teams with individuals from different backgrounds and perspectives contributes to more creative, collaborative, and impactful research. She highlights the importance of not only involving students from varied disciplines and cultures, but also patient partners, whose lived experiences bring essential insights into the research process. We also explore how a multinational and multidisciplinary approach has been central to the success of her work, particularly in translational science.

https://crhmr.ciusss-estmtl.gouv.qc.ca/en/researcher/may-griffith

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In this episode, Dr. Erin Mulvihill discusses the advancements in metabolism research that broadens our understanding of the mechanisms behind diabetes and heart health. Through models of both diseases, it is hypothesized that similar hormones and lipids can act as drug targets to improve patient outcomes.

Learn more: https://www.ottawaheart.ca/profile/mulvihill-erin-e

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Deyanira Hdez. de la Universidad de Ottawa, habla con el Dr. Sergio Alberto Bernal Chávez, Profesor del departamento de Ciencias Químico Biológicas de la Universidad de las Américas, Puebla, y miembro del Sistema Nacional de Investigadores, nivel 1. El Dr. Bernal es Químico Farmacéutico Biólogo con maestría y doctorado en Ciencias Químicas por la UNAM. Su investigación se centra en la aplicación de nanotecnología para el desarrollo de productos cosméticos innovadores. En el episodio de hoy el Dr. brneal dsmitificará ideas sobre los bloqueadores solares.

https://www.udlap.mx/profesores/Sergio-Alberto-Bernal-Chavez

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Iman Kashif from the University of Ottawa interviewed Dr. Barbara Vanderhyden, a senior scientist in ovarian cancer research and a professor at the University of Ottawa. In this insightful episode, Dr. Vanderhyden discusses her groundbreaking research pertaining to how immune regulator NLRC5 can reshape the tumor microenvironment and increase T-cell reactivity to better recognize and respond to cancer cells. She explains the mechanisms of immune evasion in ovarian cancer and discusses how her work could pave the way for novel therapeutic approaches.

Learn more: https://www.ohri.ca/profile/vanderhydenlab/profile

1:47 | Immune Evasion and NLRC5.
4:49 | Clinical Applications of NLRC5.
6:28 | Combination Therapy with NLRC5.
9:23 | Tumor Adaptation Challenges.
12:26 | Advice for Early Career Professionals.

Music Credit/Copyright information: Copyright free, Youtube video: “DEATH NOTE - L THEME SONG (RIFTI BEATS REMIX) [No Copyright Music]”. Account: Kingdom Power Music. Published January 18, 2021. https://www.youtube.com/watch?v=AkFHNQELp3Y&ab_channel=KingdomPowerMusic

Iman Kashif (Host, Audio Master), Jacqueline Aoun (Producer), Aaya Mahdi (Content Writer), Shreya Padhy (Content Writer)

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In this episode, your host, Emily Schraeder, speaks to Dr. Christian Vaillancourt, Full Professor with the Department of Emergency Medicine, University of Ottawa, and Senior Scientist at the Ottawa Hospital Research Institute. His research looks at pre-hospital care, specifically improving care and survival for cardiac arrest and trauma victims. He implemented a multi-phase protocol to allow nurses to use automated external defibrillators (AEDs) during in-hospital cardiac arrest and studied its impact on survival. His research has a major impact on the care and treatment of cardiac arrest victims in our hospitals. We also hear from Julie Considine, Deakin Distinguished Professor, who is Chair of Nursing at Eastern Health and Director of the Centre for Quality and Patient Safety Research, who gives her point of view on this protocol.

Learn more: https://www.ohri.ca/profile/cvaillancourt

1:23 | What is an AED? Why is an AED important?
3:16 | Why is the 3-minute time frame so important? Why can it take up to 12 minutes for the first shock to occur?
5:28 | Why are nurses not allowed to use AED in hospitals?
7:47 | What were the study's challenges or different opinions and views?
10:08 | From a nursing perspective, what are some strengths and weaknesses of this protocol?
12:07 | How do you expect these protocols to be implemented in the long term?
13:49 | Is there anything that you, Dr. Vaillancourt, want the listeners to know about AED use?

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Producer: Stephanie Khoury
Show host: Emily Schraeder
Writer editor: Hannah Verge and Elizabeth Thibeault
Audio master: Stephanie Khoury and Emily Schraeder

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Batoul Jomaa from the University of Ottawa interviews Dr. Marisa Azad and Dr. Robin Patel on behalf of her team for the TMM4950 Science Communication course about improving the diagnostic methods for periprosthetic joint infections (PJIs). Dr. Azad is a senior scientist and physician of infectious diseases at the Ottawa Hospital Research Institute and a cross-appointed assistant professor at the University of Ottawa. Dr. Azad's research focuses on exploring PJI to develop more efficient diagnostic methods. Dr. Robin Patel is a director of the Infectious Disease Research Laboratory and a clinician at the Mayo Clinic. In this episode, Dr. Azad and Dr. Patel present their findings from their research on new diagnostic methods for PJI, how diagnostic methods can improve, and important considerations regarding PJI.

Learn more: https://www.uottawa.ca/faculty-medicine/dr-marisa-azad

0:05 | Introduction to podcast
1:15 | Introduction to Dr. Azad
1:44 | Why is diagnosing PJIs so difficult and what are the current standard treatments?
4:20 | What is the BioFire Joint Infection (JI) panel and how does it work?
5:20 | What are the plans to improve the accuracy of the BioFire Joint Infection (JI) panel?
7:23 | How will antimicrobial resistance affect the prevalence of PJIs and diagnostic strategies?
9:25 | Introduction to Dr. Robin Patel
10:00 | Are PJIs typically caused by one or multiple microbes?
11:58 | Will biomaterials reduce the risk of PJIs or introduce new problems?
14:32 | Closing remarks

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Batoul Jomaa (Voice), Tony Lin (Post-Production), Abha Ranjitkar (Content Generation), Sam Khanlou (Producer)

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Giselle Joseph of the University of Ottawa interviews Dr. Deborah M. Siegal of the Ottawa Hospital Research Institute about how a simple change in blood collection practices in ICUs could significantly improve patient care. Dr. Siegal is a hematologist, clinician-scientist at the Ottawa Hospital Research Institute, and Associate Professor of Medicine at the School of Epidemiology and Public Health at the University of Ottawa.

Learn more: https://www.ohri.ca/profile/dsiegal

0:06 | Introduction
0:56 | Motivation behind using small-volume tubes in ICUs
3:15 | Study design and challenges
6:19 | COVID-19 and adaptations to the study
8:46 | Limitations and interpretation of results
11:23 | Next steps

Soundtrack by The Underground Drive. All rights reserved.Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Natasha Trehan (Producer), Giselle Joseph (Host), Emma Mahoney (Content Writer), Angela Guevara (Post-Production)

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Serena George, a student from the University of Ottawa, interviewed Dr. Melissa Fernandez, an assistant professor at the School of Nutrition Sciences at the University of Ottawa. Her research focuses on understanding the impacts of digital food environments on health and nutrition, with a particular interest in food literacy, eating practices, dietary intake, and mental health. In this episode, Dr. Fernandez gives insights into the research behind one of her studies that suggests that improving cooking skills and reducing processed food use may support healthier diets and overall well-being. Following this, Serena sits down with Nicholas Goulet, a Ph.D. candidate in the School of Human Kinetics at the University of Ottawa, who shares his perspective on Dr. Fernandez's research and the insights discussed in the interview.

00:19 | Main guest introduction

00:46 | What inspired Dr. Fernandez to focus on nutrition research

01:22 | Main findings of the study, 01:58 - Dr. Fernandez on her research study

04:18 | Food agency and impact of cooking skills, 05:38 Impact of Socioeconomic background, education, and culture

07:46 | Cooking skills and mental health

09:34 | Future research recommendations

11:39 | Message to listeners and general public

13:29 | Input from PhD candidate Nicholas Goulet

14:45 | Closing remarks.

Learn more: https://www.uottawa.ca/faculty-health-sciences/nutrition/our-professors/melissa-a-fernandez.

Music credits: Guitar Beat Intro / Outro 0128 by TuesdayNight on Pixabay.com (copyright-free)

Producer: Svitlana Demchenko, Show Host: Serena George, Writer editor: Nohadra Jeorje, Audio master: Anna Pawelko

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Sahib Moga from the University of Ottawa interviews Dr. Jean-François Couture. Dr. Couture is a Full Professor and Chair in the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. He has published over 90 papers in prestigious journals and is a leading structural biology and epigenetics expert. In this episode, Dr. Couture shares his research on the role of a non-canonical zinc finger in stabilizing Cfp1’s integration into the H3K4 methyltransferase complex COMPASS and its implications for epigenetic signaling and cancer biology.

Learn more: http://jfclab.ca/

0:05 | BEaTS and host introduction
1:00 | Introduction to Dr. Couture
1:58 | Introduction to epigenetics and structural biology
5: 55 | COMPASS complex and its role
8:14 | Novel zinc finger discovery
12:20 | Future treatments and drug development
13:15 | Conclusion

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Daniel Nguyen (Producer), Sahib Moga (Host), Ryan Zammar (Content Writer), Francesco Cortese (Post-Production)

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Joyce Lu from the University of Ottawa interviews Dr. Céline Aguer. Dr. Aguer is an assistant professor at McGill University in the Department of Physiology and principal investigator in her muscle metabolism laboratory at the Institut du Savoir Montfort in Ottawa. In this episode, Dr. Aguer shares her research on how bisphenol A (BPA), an environmental pollutant, disrupts muscle metabolism. This episode also features additional commentary by Dr. Ella Atlas, adjunct professor at the Department of Biochemistry, Microbioloy and Immunology and Health Canada Research Scientist on environmental pollutants.

Learn more

Dr. Céline Aguer: https://www.uottawa.ca/faculty-medicine/dr-celine-aguer
Dr. Ella Atlas: https://www.uottawa.ca/faculty-medicine/dr-ella-atlas

0:16 | BEaTS, Host introduction, and Background information.
0:55 | Introduction to Dr. Aguer
1:26 | How Dr. Aguer started research on pollutants and muscle metabolism,
2:54 | Current issues with BPA exposure and why studying BPA is important?
5:51 | Special Guest Dr. Ella Atlas Introduction
6:11 | Dr. Atlas' insights on BPA alternatives and avoidance
8:05 | How BPA can cause insulin resistance in muscle cells
11:15 | Other potential health impacts of BPA exposure
12:22 | Future Studies with the Aguer Lab
14:08 | Closing Remarks

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Joyce Lu (Podcast Host), Emily Wood (Writer/Editor), Ernest Ngou (Audio Master), Angela Wang (Producer)

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Hosein Hosseini Abardeh, from the University of Ottawa, interviews Dr. Kusum Menon, a senior scientist at the CHEO Research Institute, to explore her research into pediatric septic shock. In this episode, we dive into critical topics such as the use of corticosteroids in managing pediatric septic shock and the challenges and benefits of using a deferred consent model for patient recruitment in clinical studies. Special guest Katie O’Hearn joins to provide additional insights into the complexities of conducting research in pediatric critical care.

Learn more: https://www.cheoresearch.ca/research/find-a-researcher/kusum-menon/

0:06 | Host introduction.
0:27 | Introduction to Dr. Menon and Katie O'Hearn
1:15 | Walking through Dr.Menon's scientific journey
2:41 | Katie O'Hearn's role in the lab
3:44 | Why are corticosteroids used for pediatric septic shock?
5:28 | Challenges faced during the double-blind septic shock pilot study.
6:14 | How were the challenges with steroid usage addressed for the study?
7:52 | What is deferred consent? Why is it necessary? And how it was employed in the study.
10:13 | Walkthrough of what happens when a child dies during the study.
13:00 | Closing Remarks

This podcast features the song "Chroma Dusk" from Top-Flow on PixaBay, which is available under a Creative Commons Zero (CC0) license. Sergio Prosvirini created it.

https://pixabay.com/music/beats-chroma-dusk-269465/

Hosein Hosseini Abardeh (Host), Aaron Reyes (Producer), Malcolm Wilson (Audio), Vincent Baron (Script Writer)

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Larissa Yakoub from the University of Ottawa speaks with Dr. Betty Li, a researcher at the Human Health Therapeutics Research Center and an adjunct professor in the Department of Systems and Computer Engineering at Carleton University. In this episode, Dr. Li shares her recent findings in the development of 3D-printed materials for their application in vascular research and the creation of disease models.

Access to Dr. Betty Li and her team’s publication in Elsevier: https://doi.org/10.1016/j.bprint.2023.e00258

Learn more about Dr. Li: https://carleton.ca/sce/people/li-2/

0:03 | Introduction
1:23 | What motivated Dr. Li to advance bioprinting technology?
4:47 | Who can benefit from 3D bioprinted blood vessels?
6:40 | Innovation of AGC bioink- How Dr. Li created a special type of ink (bioink) that can mimic real living tissue to be used in 3D bioprinting
8:50 | 3D bioprinted vascular networks in drug discovery- How using 3D bioprinted blood vessels can help test new medicines
10:24 | AGC bioink and ECM remodeling- AGC bioink reshapes the framework that supports your cells
12:48| Dr. Li’s expectations for her research
15:12 | Conclusion and credits

Soundtrack by penguinmusic. All rights reserved. https://pixabay.com/music/beats-lazy-day-stylish-futuristic-chill-239287/

Podcast by Larissa Yakoub (host, writer, and audio director) and Nada Abu Khater (producer, audio director, post-production, and writer). Social media collaboration by Suad Zain Aldeen and Darah Freije.

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Tracy Xie, a student from the University of Ottawa, interviews Dr. Stephanie Willerth, a full professor and Tier II Canada Research Chair in Biomedical Engineering at the University of Victoria. In 2019, Dr. Willerth's group pioneered a new way to 3D print neural tissues using fibrinogen, a natural substance that helps our blood clot.

In addition, Dr. Willerth is the CEO and co-founder of Axolotl Biosciences, a women-led biotech company. They have created the world's first commercial neuro-ink by bringing her 3D bioprinting technology to the market with Axolotl Biosciences!

In this episode, we discuss the journey behind creating this versatile bioink, the advancements it helped lead to, and the exciting future of 3D bioprinting.

Learn more about Dr. Willerth's work here: https://www.engr.uvic.ca/~willerth/

Learn more about Axolotl Biosciences here: https://www.axolotlbiosciences.com/

0:05 | BEaTS Research Radio and host introduction
0:26 | Background on 3D bioprinting
0:51 | Introduction to Dr. Willerth and her 2019 paper
2:03 | Current landscape of 3D bioprinting
3:17 | Key takeaways from Dr. Willerth's 2019 paper
4:20 | What makes this bioink so special?
4:53 | Choosing the right materials to support stem cell growth
6:03 | Checking stem cell viability and differentiation into neurons
6:54 | The biggest challenge in developing this protocol
7:40 | Dr. Willerth's favorite parts of the project
8:29 | Advancements and applications using this bioink!
9:38 | Next steps from the Willerth Lab
11:22 | Outro, and thank you for listening!

Music by the Underground Drive. All rights reserved. Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Ryan Chan (Producer), Tracy Xie (Show Host), Abigail Shaver (Writer Editor), and Mia Petrović (Audio Master).

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As part of the BEaTS Research Radio Translational and Molecular Medicine Sci-Comm Podcast series, our host, Daniel Anderson, interviews Dr. Ruel and NP Ponnambalam. In this episode, Daniel, Dr. Ruel, and Ms. Ponnambalam discuss the promise of minimally invasive coronary bypass grafting (MICS CABG) and how it is a less invasive and safer option for patients who require coronary bypass surgery. Dr. Marc Ruel (MD, MPH) is the endowed chair of minimally invasive cardiac research at the University of Ottawa Heart Institute. He is also a Professor in the Division of Cardiac Surgery at the University of Ottawa Heart Institute. He is a Professor in the Department of Surgery and Department of Cellular and Molecular Medicine at the University of Ottawa. Menaka Ponnambalam (RN-EC, MN, NP-Adult) is a nurse practitioner in the Division of Cardiac Surgery at the University of Ottawa Heart Institute.

Learn more

Dr. Marc Ruel: https://www.ottawaheart.ca/profile/ruel-marc
Menaka Ponnabalam: https://www.ottawaheart.ca/patients-and-visitors/clinical-departments/cardiac-surgery

0:20 | Introduction to Dr. Marc Ruel & NP Menaka Ponnambalam
1:22 | Origin of the MICS CABG Procedure
4:39 | Patient Experience
6:35 | Science Behind the Magic
8:20 | Future of Cardiac Surgery
9:05 | Teamwork
10:16 | Patient Advice
13:29 | Conclusion & Resources

Music: Waltz in F# minor by Josh Zeldin & Huy K. Nguyen (unpublished composition). All rights reserved.

Huy K. Nguyen (Producer), Daniel Anderson (Host), Josh Zeldin (Writer), Gil Toex (Editor)

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Omar Moghrabi from the University of Ottawa interviews Dr. Marceline Côté about using Sphingosine Kinase (SK) Inhibitors to treat enveloped viruses like Ebola. Dr. Côté is an associate professor at the University of Ottawa and the director of the Centre for Infection, Immunity, & Inflammation, where her research and practice involve antiviral treatments. In this episode, Dr. Côté weighs in on the emerging research that suggests that the use of SK inhibitors may be the future of broad-spectrum antiviral treatments. Omar and Dr. Côté discuss the mechanism, breadth, and safety of SK inhibitors in detail and the future of this post-entry approach to viral combat.

Learn more: https://www.uottawa.ca/faculty-medicine/dr-marceline-cote

0:03 | Introduction to the speaker
1:04 | Lay Summary/intro to the topic
1:54 | How do viruses like Ebola enter cells in the first place?
4:50 | What are sphingosine kinases, and why are they such a good target for blocking viruses?
6:00 | How effective is this approach across these viruses, and were there any surprises or interesting findings?
8:48 | The future of broad-spectrum antiviral treatments and the potential of SK inhibitors
10:22 | Known side effects of using SK inhibitors and safety concerns
11:54 | Impact of SK Inhibitor Therapies on Public Health Responses During Viral Outbreaks
13:16 | Outro and Thanks

Intro: Sunny Brazilian Bossa Nova Jazz Podcast - Denis-Pavlov-Music;
Outro: Context Sensitive - CHIPTUNE
https://www.youtube.com/ContextSensitive
https://contextsensitive.bandcamp.com/

Producer: Zaid Taweel
Editor: Zaid Taweel
Script Writers and Editors: Aws Almir Ahmad and Paul Al Haddad
Show Host: Omar Moghrabi

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Matteus McCulloch from the University of Ottawa interviews Dr. Michele Ardolino, a senior scientist in cancer research at the Ottawa Hospital Research Institute and an Assistant Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. In this episode, Dr. Ardolino discusses a recent paper published by his lab about PD-L1 and its inhibition of the Type I IFN pathway during oncolytic virus infection, how the research came about, and the relevance of the work to advance cancer treatment.

Learn more about Dr. Ardolino and the work of the Ardolino Lab:
https://www.uottawa.ca/faculty-medicine/dr-michele-ardolino
https://ardolinolab.ca/

0:00 | Introduction to PD-L1 and the type I IFN pathway and its relevance to recent research by Hodgins, J.J. et al.
1:40 | BEaTS, host, and guest introduction
2:18 | What inspired the Ardolino Lab's exploration of PD-L1 and the type I IFN pathway?
5:01 | What setbacks were encountered over the course of this study?
6:35 | What is the mechanism of action for PD-L1 antibodies and oncolytic viruses in cancer therapy?
8:17 | Clinical applications of PD-L1 antibodies and oncolytic viruses for cancer therapy
9:50 | Impactful moments during the research process
10:57 | Next steps in PD-L1 research
12:02 | Advice for students entering research
13:30 | End credits

This podcast features the following songs:
"Hidden Realm" by I.V.Lab, available under a Creative Commons Attribution-NonCommercial license.
Listen here: https://archive.org/details/ffs62
"600 light years" by Macroform, available under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 license.
Listen here: https://archive.org/details/Macroform2011

Matteus McCulloch (Podcast Host), Serena Bezanson (Script Writer), Sara Ladha (Audio post-production), Mattheuren Aucoin (Producer).

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In this episode, Ali Abdalbari from the University of Ottawa's Translational and Molecular Medicine (TMM) program speaks with Dr. Morgan Fullerton, Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. This episode features a discussion surrounding Dr. Fullerton’s most recent paper, published in the Atherosclerosis Journal (https://doi.org/10.1016/j.atherosclerosis.2024.117608). Dr. Fullerton provides an in-depth overview of his team’s discoveries and offers his expertise in the field of metabolic research, highlighting the importance of model systems of disease and the implications of his research in this field.

Learn more: https://doi.org/10.1016/j.atherosclerosis.2024.117608

Fullerton Lab: https://www.fullertonlab.com/

0:10 | BEaTS and host introduction
0:39 | Introduction to Dr. Fullerton
1:39 | Podcast topic introduction
1:56 | Guest welcome
2:08 | Introduction to atherosclerosis
3:44 | Focus of the Fullerton lab: metabolism and AMPK
6:32 | Interlude: a study from collaborator Dr. Kim Loh
7:04 | Concept of “negative data”
7:43 | Data and challenges
10:16 | Impact of research on the field of atherosclerosis
11:33 | Accessibility and efficient communication in science
13:23 | Podcast Outro

Soundtrack by the Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Podcast credits: Ali Abdalbari (Show Host), Brianna Kore (Audio Master), Michelle Levesque (Writer Editor), Peter Noel (Producer).

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Anastasia Fahlman and Sarah Damiani from the University of Ottawa speak with Dr. Erin Mulvihill, Scientist and Director of the Energy Substrate Metabolism Research Laboratory at the University of Ottawa Heart Institute. Tune in to learn more about her recent work published in CellPress, which explores the potential mechanisms underlying the cardioprotective benefits of metabolic surgery and GLP-1RA-based therapies. It also discusses recent evidence and emerging therapies in this dynamic area of research.

Learn more: https://www.sciencedirect.com/science/article/pii/S1043276024001930

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Podcast by Sarah Damiani (Voice, Producer, Show Co-Host, Writer Editor, Audio Master) and Anastasia Fahlman (Voice, Show Co-Host, Writer Editor, Audio Master)

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Lia Morton from the University of Ottawa interviews Dr. Marisa Azad. Dr. Azad is a physician-scientist at the Ottawa Hospital Research Institute and an Assistant Professor of medicine in the division of infectious diseases at the University of Ottawa. In this episode, Dr. Azad shares her insight and expertise on implant-associated infections (IAIs), notably the challenges of detecting and diagnosing IAIs and emerging diagnostic methods.

Learn more: https://www.ohri.ca/newsroom/story/view/1543?l=en

0:00 | BEaTS and host introduction.
0:38 | Introduction to Implant-Associated Infections (IAIs)
1:40 | Introduction to Dr.Azad.
2:11 | Why is IAI diagnosis so difficult, and what makes it particularly challenging?
3:39 | Implant types that are notably hard to detect.
4:29 | How do biofilms contribute to the formation of IAIs, and what makes them dangerous?
7:41 | Limitations associated with microbiological analyses.
11:09 |Future work and new approaches considered to identify IAIs.
12:59 |The diagnostic methods currently being used in the clinic
14:26 | Farewells and closure.

Soundtrack by The Underground Drive. Song Titled: BEaTS. All rights reserved.

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Lia Morton (Show Host, Content Generation), Julianne Morin (Production, Content Generation), Amal Assebbane (Script, Content Generation), Adjia Seynabou Sy Gueye (Post-Production, Content Generation)

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Maheen Khanotia from the Translational Molecular Medicine program interviews Dr. Barabara Vanderhyden, a distinguished researcher at the Ottawa Hospital and a professor at the University of Ottawa. She is a leading researcher in ovarian cancer, focusing on the BRCA1 and BRCA2 mutations. In this podcast, Maheen discusses with Dr. Vanderhyden her key findings in her 2023 paper "BRCA1 and BRCA2 deficient tumor models generate distinct ovarian tumor microenvironments and differential responses to therapy," where they delve into the world of cancer, Dr. Vanderhyden's lab findings, potential treatments, and research advice.

Learn more: https://www.ohri.ca/profile/vanderhydenlab/profile

0:05 | BEaTS and host introduction.
1:17 | Introduction to Dr. Barbara Vanderhyden.
1:39 | How did you come to study ovarian cancer?
2:48 | What led you to believe the BRCA1 and BRCA2 mutations are different?
3:50 | What is the tumor microenvironment?
4:57 | What do the research findings mean to the general public?
6:05 | Why do BRCA1 and BRCA2 deletions at the gene and protein levels have different effects on tumor microenvironments?
8:04 | What were the challenges you went through as a researcher?
9:18 | What were the crucial limitations of your research?
10:24 | What are the future steps for ovarian cancer research?
11:56 | What is general advice you would give to other researchers?
12:55 | How long does a study like this take?
13:40 | How does this research affect a patient's diagnosis?
14:31 | Closing remarks

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

Maheen Khanotia (Voice, host, editor), Soniya Agarwal (Producer, writer)

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Join Kahliana Nguyen and Khaled Najjar, Translational and Molecular Medicine students, as they speak with Dr. Baptiste Lacoste, a neuroscience researcher at the Ottawa Hospital Research Institute whose recent work focuses on the critical role of the brain’s vascular system in development.

The episode explores a new perspective on autism spectrum disorders (ASD) and how problems with the brain’s blood vessels in early development may contribute to challenges seen in autism. Dr. Lacoste goes into depth on how these blood vessels play a role in brain growth, energy use, and behavior. By studying these interactions alongside neural and genetic factors, his research opens new avenues in how we understand autism and find better ways to address ASD. Whether you’re a researcher, student, or simply curious, this episode offers an exciting new lens to the field.

Learn more: Dr Baptiste Lacoste

Dr Baptiste Lacoste | Faculté de médecine

https://bsky.app/profile/blacoste.bsky.social

https://www.ohri.ca/profile/lacostelab

0:02 | BEaTS and host introduction.
0:22 | Introduction to Dr. Lacoste
1:10 | Why did Dr. Lacoste choose to focus on the vascular system specifically?
3:05 | The Neurovascular unit (NVU) and its importance in Dr. Lacoste's research on ASD
5:15 | The use of mice with a 16p11.2 deletion mutation to study ASD
8:43 | The novel findings were seen in Dr. Lactoste's lab study on ASD
10:51 | Treatment Strategies when it comes to ASD
12:03 | Limitations & Challenges Dr. Lacoste's lab faced and still faces while studying ASD
13:50 | Wrapping up the episode

Science and Innovation by Vicate. All rights reserved. Listen more:
https://www.jamendo.com/album/578641/science-and-innovation
Vicate | Jamendo Music | Free music downloads

Kahliana Nguyen (Voice) & Khaled Najjar (Producer & Editor)

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Maryam Yassin from the University of Ottawa interviews Dr. Anna Jezierski and Dr. Alex MacKenzie. Dr. Jezierski is a research officer at the Department of Translational Biosciences in the Human Health Therapeutics Research Center at the National Research Council of Canada. She is also an adjunct professor for the Department of Biochemistry, Microbiology, and Immunology at the University of Ottawa. In this episode, Dr. Jezierski shares her research on modeling the human blood-brain barrier using induced pluripotent stem cells and the various applications of this model in studying therapeutics for diseases of the central nervous system. We're also joined by Dr. Alex Mackenzie, an attending pediatrician and senior scientist at the Children's Hospital of Eastern Ontario (CHEO). He has served as the CEO and Scientific Director of CHEO Research Institute and is a cross-appointed member of the Faculty of Medicine at the University of Ottawa. Dr. Mackenzie comments on how this model is revolutionizing drug development.

Learn more: https://www.uottawa.ca/faculty-medicine/dr-anna-jezierski
https://www.cheoresearch.ca/research/find-a-researcher/alex-mackenzie/

0.03 | BEaTS and host introduction.
0.26 | Introduction to Dr. Jezierski.
1.17 | Introduction to Blood-Brain Barrier (BBB).
3.22 | Creating a BBB model using induced pluripotent stem cells is important.
7.07 | How tight junctions are replicated effectively.
9.20 | Applications of the iPSC-derived BBB model.
12.35 | Introduction to Dr. Alex Mackenzie
12.51 | Implications of the model on drug discovery and clinical trials.
14.54 | Closing remarks.

Soundtracks by the Underground Drive. All rights reserved. Listen more
https://www.dropbox.com/scl/fo/yrgjajtxzy4j08zj5iptc/AF7HMueoQwogLQMFxHxSHpU?e=1&preview=BEaTS+-+music+only+2.wav&rlkey=epcpj63eohwgi44mnqg7ctoa6&st=bn1v69ik&dl=0

Maryam Yassin (Voice), Aysha Aftab (Post-Production), Dalia Zeidan (Content Generation), Jordan Yin (Producer).

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In this episode, Celina Tanbari from the University of Ottawa interviews Dr. Adam Rudner about the fascinating world of bacteriophages—viruses that target and kill bacteria. Dr. Rudner is the coordinator of the University of Ottawa’s Phage Hunters program, a member of the SEA-PHAGES and SEA-GENES programs, and an Associate Professor in the Department of Biochemistry, Microbiology, and Immunology. Dr. Rudner shares with us his expert opinion on a study that isolated bacteriophages from human skin to kill infection-causing bacteria. The discussion delves into the therapeutic potential of phages, their involvement in biofilms and lysogeny, and the challenges associated with utilizing phages in medicine.

This episode was produced and written by Emma Etchells Foisy, hosted by Celina Tanbari, and audio edited by Sam Rogers. Copyrights are reserved to BEaTS Research Radio and the University of Ottawa.

If you are interested in learning more about the paper we discussed today, you can find it through the following link: https://pmc.ncbi.nlm.nih.gov/articles/PMC10117716/

Learn more: https://www.uottawa.ca/faculty-medicine/dr-adam-rudner

0:03 | BEaTS and host introduction.
0:38 | Introducing Dr. Rudner.
1:05 | What are bacteriophages?
1:41 | Phages as a possible solution to antibiotic-resistant bacteria
2:41 | What are biofilms, and how do they affect bacterial infections?
5:01 | Phage BE01 and how lysogeny can affect phage therapy.
8:52 | Phage BE04 and the potential of phages in replacing antibiotics.
10:55 | Squashing the stigma, phages only attack bacteria.
12:35 | Potential challenges with phage therapy.
14:08 | Dr. Rudner's take-home message.
14:36 | Thank yous and credits!

Soundtrack, Chillout by AudioCoffee | https://www.audiocoffee.net/
Music promoted by https://www.chosic.com/free-music/all/
Creative Commons CC BY-SA 3.0
https://creativecommons.org/licenses/by-sa/3.0/

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A series of interviews with presenters and participants at the Music and Health Research Institute's annual conference at The Royal Ottawa Mental Health Centre. This episode serves as an introduction to the ongoing work of institute members in the field of Music and Health research and practice.

Lucas Marchand (Interviewer, Post-production, Content generation, Producer)

Learn more: https://www.uottawa.ca/research-innovation/music-health

0:02 | Host introduction.
0:29 | Interview with Dr. Jane Gosine of Memorial University
2:15 | Interveiw with Ludovic Dubé
4:34 | Interview with Dr. Chi Lo of Singwell
9:45 | Interview with Dr. Erin Parks of Lotus Centre
14:15 | Interview with Cory Butler of Zamar Music

Original music written and recorded by Lucas Marchand

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Nicole Chu from the University of Ottawa speaks with Dr. Javed Butler. Dr. Javed Butler, MD, MPH, MBA, is the President of the Baylor Scott and White Research Institute, and Senior Vice President and Maxwell A. and Gayle H. Clampitt Endowed Chair at the Baylor Scott and White Health in Dallas, Texas. He is also the Distinguished Professor of Medicine at the University of Mississippi in Jackson, Mississippi. In this episode, Dr. Butler shares with us the major findings from the recent EMPACT-MI clinical trial and his perspective on the future of heart failure therapies. The EMPACT-MI trial investigated whether a medicine called empagliflozin, a SGLT2 inhibitor, helps to lower the risk of heart failure and death in people had experienced a heart attack (myocardial infarction).

Learn more about the EMPACT-MI clinical trial https://www.nejm.org/doi/full/10.1056/NEJMoa2206286

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Nicole Chu from the University of Ottawa speaks with Dr. Rosalin Miles. Dr. Miles is an active community member of the Lytton First Nation and a Research Associate in the Indigenous Health and Physical Activity program at The University of British Columbia School of Kinesiology. Her research focuses on the promotion of Indigenous health and wellness and understanding the value of traditional, cultural, and historical knowledge using a strength-based approach. Dr. Miles founded the Indigenous Physical Activity and Cultural Circle (IPACC), a national non-profit for First Nations, Métis and Inuit people who are involved in Traditional Activities, Fitness, Recreation, and Sports.

Tune in to this episode to learn more about how the IPACC creates a community to promote physical activity as a way to health and wellness.

Register for the upcoming National Indigenous Physical Activity & Wellness Conference Date: May 15th & 16th, 2024
https://iactive.ca/conference/

Learn more: https://iactive.ca

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Ryan Tu speaks with Dr. Emmanuel Stamatakis, a professor of physical activity, lifestyle, and population health at the University of Sydney, and a NHMRC Leadership 2 Fellow. Dr. Stamatakis focuses on cohort study-based research to correlate physical exercise to health. In this episode, Dr. Stamatakis explains his role in the Prospective Physical Activity, Sitting and Sleep consortium (ProPASS), how this helped him lead the development of activity guidelines for the World Health Organization, and how exercise is incorporated to the daily routine.

Learn more: https://www.sydney.edu.au/medicine-health/about/our-people/academic-staff/emmanuel-stamatakis.html

Episode produced by Nicole Chu and hosted by Ryan Tu.

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Jinane El-Hage from the University of Ottawa interviews Dr. Martin Gibala from the University of McMaster. Dr. Gibala is a professor of kinesiology, and his research focuses on the beneficial effects of exercise at the molecular to whole body level in both healthy individuals and those with chronic diseases. Dr. Gibala and his team are renowned for their work on high-intensity interval training and its impact on health, performance, metabolism, and even cognitive function. Dr. Gibala's expertise has led to the publication of "The One Minute Workout: Science Shows a Way to Get Fit That's Smarter, faster, and Shorter," a book that offers science-backed exercises and workouts for individuals seeking to achieve their health and fitness goals. Have you sought science-backed exercises and workouts that suit your lifestyle and health goals? Look no further as Dr. Gibala dives deep into what makes a healthy, practical, and uncomplicated exercise lifestyle.

Learn more: https://martingibala.com/

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Deyanira Hernandez from the University of Ottawa interviews Dr. Catherine Sabiston, an exercise and health psychology professor at the University of Toronto. Dr. Sabiston holds a Canada Research Chair in physical activity and mental health to conduct research on understanding physical activity, motivation, and mental health, including body image, physical self-perceptions, anxiety, depression, and stress. In this episode, Dr. Sabiston talks about her motivation to pursue a career in physical activity and mental health, the differences between multi-sport vs. single-sport approaches, and finally, she gives some advice for the community about how to create a more inclusive and appropriate environment where adolescents do not develop body-related shame and guilt.

Learn more: https://kpe.utoronto.ca/faculty/sabiston-catherine

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Armita Kalani from the Translational and Molecular Medicine (TMM) program at the University of Ottawa interviews Dr. Shawn Beug on behalf of her team for the TMM4950 Science Communication course. Dr. Shawn Beug is a Scientist at the CHEO Research Institute and an Assistant Professor at the University of Ottawa. Dr. Beug’s research group focuses on understanding the factors involved in apoptosis (programmed cell death) and aims to develop new immune-based therapies for the treatment of cancer. In his quest to defeat cancer, Dr. Beug shares with us his research on a new class of drugs known as 'SMAC mimetics' as well as major findings from his 2017 Nature paper on the use of SMAC mimetics for glioblastoma treatment, and the results from ongoing clinical trials.

To learn more, please visit: https://med.uottawa.ca/bmi/en/people/beug-shawn

Episode credits: Ana Spasojevic (Producer), Armita Kalani (Host), Nicole Chu (Content Writer), Kirsten Chua (Video Editor)

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Areej Khanotia, a student in the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Patrick Fafard. Dr. Fafard is a full professor and
also serves in leadership roles for the Global Strategy Lab at York University and the
University of Ottawa, the Centre for Health Law, Policy and Ethics, the Institute for
Science, Society and Policy, and the Ottawa Hub for Harm Reduction. In this episode, Dr. Fafard shares his insight on the illusions and implications of the ‘just following the science’ rhetoric in COVID-19 messaging.

We explore whether policy makers are actually "following the science" or hiding behind experts to dodge
the blame.

Learn more: https://www.globalstrategylab.org/people/patrick-fafard/

0:08 | BEaTS and Host Introduction
0:55 | Introducing Dr. Patrick Fafard!
1:30 | Overview of study being discussed
4:45 | Negative concequences for leaders that rely on "the science"
7:45 | Positive concequences for leaders that "follow the science"
10:04 | Recommendations for leaders facing future healthcare crisis
11:52 | Future research plans extending from this work
13:55 | Connecting with Dr. Fafard

Podcast by Areej Khanotia (Show Host), Hiba Alami Chentoufi (Audio Master), Hoda Osman (Writer Editor), Madeeha Shaikh (Producer)

Music by the Underground Drive. All rights reserved. Listen more

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Megan Verma from the University of Ottawa interviews Dr. Ian Colman for the TMM4950 Science Communication podcast assignment. Dr. Colman is a professor in the School of Epidemiology and Public Health at the University of Ottawa, and he directs the Applied Psychiatric Epidemiology Across the Life-course (APEAL) Lab. In this episode, Megan explores Dr. Colman's research on how prenatal maternal stress negatively impacts children's behaviour and mental health after birth. In the conversation, they highlight the impact of parenting on children — positively noting how effective parenting can mitigate adverse behaviours.

Learn more: https://med.uottawa.ca/epidemiology/people/colman-ian

0:06 | Podcast opening segment and introduction by host Megan Verma
0:24 | Introduction to Dr. Ian Colman, his research, and the fetal programming hypothesis
3:15 | Objectives of Dr. Colman's paper on prenatal maternal stress, children's mental health, and parenting
6:32 | Impacts of prenatal maternal stress on children
8:18 | Environmental factors contributing to mental health or behavioural problems in early childhood
9:29 | Parenting behaviours that reduce the impact of prenatal maternal stress on children's mental health
11:06 | Sex specific effects of parenting methods
12:02 | Decreasing stress levels for pregnant people on a wider scale

Podcast by Megan Verma (Host), Nassima Marouf (Producer), Ayesha Syed (Writer), Jenny Zhang (Audio Editor).

This podcast features a song "Vibe Out" by Ellis Breen, available under a Creative Commons Attribution-NonCommercial license. Listen more:
https://archive.org/details/EMC23001An_Hour_Of_EMCradio/015_Vibeout-Ellis_Breen.mp3

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In this episode, Dr. Luca Pellegrini is interviewed by Olivia Hillier, with narration by Andrew Cao, from the University of Ottawa. Dr. Pellegrini is a new professor in the department of Biochemistry, Microbiology, and Immunology and is an expert on mitochondria and inter-organelle contacts. He joins us to discuss his team’s most recent paper, published in Cell Reports (https://doi.org/10.1016/j.celrep.2021.108873). This publication describes his team’s discovery of the “wrappER”, a microscopic superhero in your body that plays a vital role in keeping you in top shape. Dr. Pellegrini takes us through the history of inter-organelle contacts research, the intriguing results detailed in his paper, and the broader implications of his findings to human health.

Learn more: https://www.pellegrinilab.com/

0:27 | Podcast team introduction
0:42 | Meet the wrappER, the cloak that safeguards your metabolic health.
2:02 | Meet Dr. Luca Pellegrini, the founder of the wrappER.
3:00 | How did Dr. Pellegrini come to study the wrappER?
3:46 | Why does Dr. Pellegrini like history so much?
4:41 | When did researchers start to consider how contacts between organelles may be important?
5:58 | Diseases related to defects in inter-organelle contacts.
6:48 | What you need to know about Anastasia et al., 2021: the paper that discovered and defined the wrappER.
8:12 | The wrappeR's structure is like a burrito.
8:43 | Are all mitochondria wrapped by the wrappER?
9:01 | The wrappER is not limited to liver cells.
9:38 | What else can the wrappER wrap?
10:12 | Dynamics of the wrappER and mitochondria.
11:32 | How long did it take to make these discoveries of the wrappER?
11:44 | The team behind the discovery.
12:40 | What the wrappER can teach us about how our bodies regulate fat.
13:18 | The wrappER and treatments for fat-related diseases and disorders.
13:55 | Dr. Pellegrini's plans as a new profressor and principal investigator at the University of Ottawa.
14:22 | Wrapping up: thank you to Dr. Pellegrini

Podcast by Andrew Cao (Narrator and Post-Production), Olivia Hillier (Interviewer), Olivia Sommers (Producer), & Anna Wang (Writer-Editor).

Music:
“The Launch” by Chronox (https://freemusicarchive.org/music/Chronox_2/)
This song can be found on the Free Music Archive (https://freemusicarchive.org/music/Chronox/Voyager/Chronox_-_01_-_The_Launch/)

“Nocturnal (BGM)” by LEMMiNO (https://www.lemmi.no/)

“Thannoid” by Blue Dot Sessions (https://www.sessions.blue/)

“Are We Loose Yet” by Blue Dot Sessions (https://www.sessions.blue/)

“Here” by Hyson (https://iamhyson.bandcamp.com/)

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Alzheimer's is a disease unique in the lack of treatment dand diagnostic techniques aimed at mitigating it's effects. To address these issues, researchers at Dr. Clifford Cassidy’s neuroscience lab are investigating the use of novel imaging techniques that have great potential to improve both our understanding of molecular mechanisms underlying Alzheimer’s and improve our ability to predict the development of it’s symptoms. At the heart of these new techniques is a brain structure called the locus coeruleus (LC), which is the primary site of release of a chemical called norepinephrine. It has already been established that gradual degeneration of the LC is an important feature of alzheimer’s disease. However, the contribution of this degeneration to development of disease symptoms remains poorly understood due to limitations in existing imaging techniques. To solve this issue, Dr. Casidy’s lab is investigating the use of Neuromelanin, a pigment found abundantly in the LC to more accurately detect this structure’s degeneration and its relation to Alzheimer’s and its symptoms.

Learn more: https://www.cliffordcassidy.com/

00:00 I Podcast Introduction
02:32 I Overview of the Cassidy Lab
4:24 I What is NM-MRI?
6:40 I Overview of the Paper about NM-MRI
9:40 I What is the role of neuroadronergic system in psychotic symptom progression?
12:20 I What is the broader role of NM-MRI
14:30 I Outro

Podcast by Patrick Chary(Host), Abdul Karim Halal (Producer), Elijah Van Dinther (Script), Nicholas Lafreniere (Editor).

Soundtrack by the Underground Drive, Song title: Nobody. All rights reserved.
Listen more: https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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This episode of Beats Radio, hosted by Danyaal Ansari, written by Shay Patel, produced by Hasssan Taleb, and edited by Anas Khoja, features an in-depth discussion with immunology expert Dr. Michele Ardolino from the University of Ottawa and the Ottawa Hospital Research Institute. The conversation centers around the fascinating interplay between the immune system and cancer, with a particular focus on the process of trogocytosis and its role in immune evasion by cancer cells. Dr. Ardolino elaborates on his groundbreaking research into how cancer cells transfer PD-1 to Natural Killer (NK) cells via trogocytosis, effectively inhibiting these critical components of the immune response. This detailed exploration sheds light on the sophisticated mechanisms cancer cells employ to evade immune detection and opens up discussions about potential therapeutic strategies targeting these interactions.

https://www.ohri.ca/profile/mardolino/cancer-immunology-lab

0:00 - Introduction
0:57 - Trogocytosis Explained
2:51 - Choosing Trogocytosis for PD-1 Transfer Study
5:00 - NK Cells' Functional Variability
8:10 - Immune System's Complexity & Beauty
10:50 - Rapid Fire Q&A
14:27 - Closing Remarks

Podcast by Danyaal Ansari (Host), Shay Patel (Writer), Hasssan Taleb (Producer), Anas Khoja (Editor)

Music by "Podcast Background Music" https://www.youtube.com/watch?v=cdFqvdekuvI

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In the latest episode of 'Neural Networks,' your Neural Networks host Lillian Abebe, a passionate advocate for neuroscience and neurophilosophy, engages in a thought-provoking conversation with Dr. Georg Northoff. As a distinguished philosopher, neuroscientist, and psychiatrist leading the Mind, Brain, and Neuroethics Research Unit at the Royal Institute of Mental Health Research, Dr. Northoff shares profound insights into the intersection of philosophy, neuroscience, and psychiatry.

Explore the intricacies of distinguishing between the brain and the mind, unravel the conceptual illusions of consciousness, and dive into the development of biomarkers for conditions like Complete Locked-In Syndrome (CLIS). Join Lillian and Dr. Northoff as they discuss the challenges of defining consciousness in scientific terms and the latest breakthroughs in understanding the connections between the brain and the mind.

Learn more: www.georgnorthoff.com

3:33 | Distuinguishing brain from mind
5:32 | Areas of development in elucidating brain-mind connections.
7:08 | Techniques used to measure consciousness
12:15 | The importance of making science accessible

Podcast by Abby Cherinet (producer), Lillian Abebe (host), Selam Yimer (writer), Xeius Tran-Wong (editor)

Soundtrack by Blue Fox Music through Renderforest

https://bluefoxmusic.com/

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Amy Stewart from the University of Ottawa speaks with Dr. Marta Cerruti, a professor in the Department of Mining and Materials Engineering at McGill University, a prominent figure in the research field of bio-synthetic materials, and the team leader of the Bio-Interface lab. As of today, Dr. Cerruti is the co-director of the McGill Institute for Advanced Materials and an associate member of the Faculty of Dentistry and the Department of Bioengineering. In the Bio Interface lab, her work centers around the incorporation of implants, tissues and drugs into the human body, as well as how minerals such as calcium and magnesium are formed in living organisms that help her address the questions of curing mineral-based diseases. Today, we'll be discussing her work centering around mineral deposits that lead to aortic valve stenosis.

Learn more: https://www.mcgill.ca/materials/marta-cerruti

0:15 l Introduction to BEaTS and Dr. Cerruti
1:25 l What is aortic valve calcification and what are the causes?
2:54 l Are there other minerals that develop in the heart?
3:45 l What are the methods used to view clacium deposits?
7:06 l Differences in calcification between men and women
12:01 l Future research
14:10 l Conclusion
14:45 l Credits

Podcast by Amy Stewart (Show Host), Shikshita Singh (Producer), Minh Tran (Writer Editor), Jade Gamelin Kao (Audio Master).

Soundtrack by Lexin_music featuring the song "sicence documentary". All rights reserved. Listen more: https://pixabay.com/music/build-up-scenes-science-documentary-169621/

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Fiona Haugen of the University of Ottawa speaks with Dr. Smita Pakhale of the Ottawa Hospital Research Institute about the impact of health inequities on the development of obstructive lung diseases in urban poor populations. Dr. Pakhale is a Senior Scientist, staff respirologist at The Ottawa Hospital, and associate professor at the University of Ottawa who created The Bridge Engagement Center. The Bridge conducts research in partnership with and to improve the well-being of underserved populations in Ottawa, Ontario.

Learn more: https://bridgeengagement.ca/

00:05 | Introduction
01:10 | Overview of Dr. Pakhale's research
02:51 | The Bridge Engagement Center
03:44 | Tobacco and Ottawa's urban poor population
05:51 | Social determinants of health and lung disease
07:18 | Building trust with marginalized communities
09:15 | Unjustified exclusion of underserved communities in mainstream research
11:22 | Addressing inequities in health and research
13:01 | How can we do our part?
14:12 | Conclusion and thanks

Podcast by Fiona Haugen (host and graphic design), Amandine Courtemanche (writer), Mairead Green (producer), Jade Poirier (audio-producer and writer)

Soundtrack by Grand_Project from Pixabay. All rights reserved. Listen more:

https://pixabay.com/users/grand_project-19033897/?utm_source=link-attribution&utm_medium=referral&utm_campaign=music&utm_content=177572

https://pixabay.com//?utm_source=link-attribution&utm_medium=referral&utm_campaign=music&utm_content=177572

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Nandini Biyani from the Translational and Molecular Medicine program at the University of Ottawa interviews Dr. Leila Mostaço-Guidolin, an assistant professor at Carleton University in the Department of Systems and Computer Engineering. With a focus in 3D-bioprinting, Dr. Mostaço-Guidolin leads a tissue engineering and bioimaging lab. In today's podcast, Dr. Mostaço-Guidolin dives into her research regarding the use of a microfluidic-based 3D bioprinting technology to synthesize new vasculature.

Learn more: https://carleton.ca/mostacoguidolin/

0:28 | Topic Introduction
0:36 | Guest introduction
1:25 | Interest in the field of 3D bioprinting?
3:23 | Elaborating on the study
4:51 | Specific choice of SV-ARBEC cells
8:31 | What is microfluidic-based 3D bioprinting?
9:56 | Limitations of the study
12:56 | Future steps
14:00 | Catch you later!

This podcast was produced by Nandini Biyani (the show host), Esha Gahunia (the writer editor) & Gurrose Gahla (the audio master).

Soundtrack by The Underground Drive. All rights reserved. Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Siyona Kassel, a Translational and Molecular Medicine student at the University of Ottawa, interviews Dr. Juan Valerio Cauich-Rodriguez. Dr. Cauich-Rodriguez is a researcher at the Centro de Investigación Científica de Yucatán in Mexico, possessing a Bachelor of Science in Industrial Chemistry, a Masters in Polymer Science & Technology, and a PhD in Biomedical Materials. He is currently engaged in the development and assessment of new materials for their role in Regenerative Medicine, with a specific focus on the use of synthesized polymers. In this episode, Dr. Cauich-Rodriguez discusses his research using a unique and innovative polymer blend to advance the field of vascular grafts for medical application.

Learn more: https://www.cicy.mx/unidad-de-materiales/investigador/juan-valerio-cauich-rodriguez

0:21 I Introduction: Cardiovascular grafts
0:49 I Intro to Dr. Juan Valerio Cauich-Rodriguez
1:29 I Dr. Cauich-Rodriguez's science background and current research
3:08 I Polymers for biomedical applications in Mexico
4:21 I What are polyurethanes?
6:39 I Biomaterials as a treatment for cardiovascular disease
8:40 I Designing synthetic vascular grafts with polymer blends
10:40 I Staying on top of the latest advancements in the field of regenerative materials
12:05 I Personalized medicine and biomaterials
13:29 I Dr. Cauich-Rodriguez's future directions

Podcast by Siyona Kassel (Voice), Caleb Lakhani (Content Generation), Paul Nguyen (Producer and Post-Production)

Credits for music: Soundtrack provided by the Underground Drive all rights reserved.
Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Zachary Mitchell from the University of Ottawa speaks with Angelico Obille, a PhD candidate at the University of Toronto Institute of Biomedical Engineering in the Biological & Bioinspired Materials Laboratory. Tune in to learn more about their research on proteins involved in freshwater mussel adhesion and how this can be applied to develop new medical adhesive technology.

Learn more: https://www.sonelab.bme.utoronto.ca/

00:04 I Intro
01:05 I Why is it important to study freshwater mussel adhesion?
02:15 I What is a byssal proteome and what does it show us?
04:16 I What's special about the proteins of zebra mussels that allows them to stick so well to wet surfaces?
07:38 I Can you explain why you don't fully agree with considering these mussels as an invasive species?
11:52 I How have these mussels impacted our ecosystem?
13:24 I What do you think about biocontrol and do you think there is a way to live harmoniously with these animals?
14:15 I Outro

Podcast by Liliana Austin, Safa Ghaziasgar, Samarth Chauhan, and Zachary Mitchell

Soundtracks by the Underground Drive. All rights reserved. Listen more:

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Devin Brain from the University of Ottawa interviews Dr. May Griffith. Dr. May Griffith is a lead researcher at Université de Montreal and holds a Canada Research Chair in Biomaterials and Stem Cell Ophthalmology. She is one of the brilliant minds behind the development of LiQD Cornea, an injectable liquid that gels in the eye to help heal corneal perforations. In this episode, Dr. Griffith shares the story that inspired her to study eye conditions and shares her incredible research focused on developing a gel for corneal regeneration.

Learn more: https://www.griffithresearch.ca/may-griffith-2

0:07 | BEaTS and host introduction
0:37 | Statistical introduction to the cornea
1:01 | Introduction to Dr. May Griffith
1:40 | Dr. Griffith's story of inspiration
3:30 | What is a corneal perforation and how are they aquired?
4:25 | Addressing problems with current treatments for corneal perforations using LiQD Cornea
6:07 | LiQD Cornea administration route in relation to accessibility
8:00 | Future plans for LiQD Cornea treatment
9:15 | What should patients expect from this treatment, short and long-term?
10:46 | Closing remarks and credits

Erica Anderson (script writing), Devin Brain (host), Rosalie Salati (audio editor), Tamara Synek (script writing). All shared role of producer

Soundtrack by The Underground Drive. All rights reserved. Listen more:
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Anabella Nakhle from the University of Ottawa interviews Dr. Stephanie Willerth. Dr. Stephanie Willerth is the CEO of Axolotl Biosciences, a 3D bioprinting company in Victoria, BC. She is also a a Canada research chair and full professor of Biomedical Engineering at the University of Victoria, and an Adjunct Professor at the University of Missouri. In this episode, Dr. Willerth shares about her research in developing a 3D bioprinted Alzheimers disease model that replicated the native tissue environment.

Learn more: https://www.engr.uvic.ca/~willerth/

https://www.axolotlbiosciences.com/

Anabella Nakhle (Voice), Serena Solari, Elie Njeime, and Mathania Vuningoma (Post-production, graphic designer and producer)

0:06| BeaTs and host introduction.
0:29 | Topic introduction.
0:59| Introduction to Dr. Willerth
1:47| Introduction to 3D bioprinting and bioink that was used for the disease model
2:43|Why was alzheimer's used as the disease model in this paper?
3:55 |Differences in modeling parkinson's disease vs alzheimer's disease.
4:30| Cell viability in the bioink
5:20| markers for cell death
6:00 | The future and challenges of 3D bioprinting in disease model development
7:14| Ethical issues that are faced with using patient-derived tissue
8:55| Ensuring the genotype of the induced pluripotent stem cells (iPSCs)
10:20| membrane potential of the bioprinted cells
11:10| Future involvement in the bioprinting field for listeners

Soundtrack by Funky Giraffe. All rights reserved. Listen more:

https://open.spotify.com/track/1ZOKcgiydsTA6OVdkraVN5
https://artlist.io/royalty-free-music/song/are-you-ready-for-me-baby/63852

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Meron Samuel Demissie from the University of Ottawa speaks with Dr. Jean-François Couture, Full Professor and Chair in the Department of Biochemistry, Microbiology and Immunology in the Faculty of Medicine at the University of Ottawa. Tune in to learn more about their studies on structural biology and epigenetics to understand the importance of small molecules and proteins' functions for the treatments of different conditions such as cancer.

Learn more: http://jfclab.ca/

0:15 | Introduction and Description
1:27 | X-Ray Crystallography
2:55 | Epigenetic Processes
5:15 | Role of X-Ray Crystallography in protein-protein interaction, precisely histones
10:13 | Closing Remarks and Advice for trainees

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more
https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Félix Labonté, an undergraduate student in the Translational and Molecular Medecine program at the University of Ottawa speaks with Dr. Dylan Burger. Dr. Burger is an associate professor at The University of Ottawa in The Department of Cellular and Molecular Medicine, cross-appointed member in the School of Pharmaceutical Sciences, and an investigator at The Ottawa Hospital Research Institute. Tune into today's podcast to learn more about Dr. Burger's research, published in the Journal of Extracellular Vesicles which demonstrates how extracellular vesicles secreted by the kidneys could potentially be used for targeted therapy advancing our knowledge on diabetic nephropathy and treatments.

Learn more: https://www.ohri.ca/profile/dylanburger

0:16 | Introduction
1:00 | Dr. Dylan Burger Introduction
1:44 | What are extracellular vesicles and what role do they play in healthy cells?
2:52 | What is diabetic nephropathy and why is your lab interested in this condition?
3:55 | What is the impact of diabetic kidney disease on microparticles released by the podocytes?
4:35 | What is the impact of the microparticles released by the podoocytes?
5:57 | What would be the next steps for your lab to complete to understand the mechanism of intracellular communication between the podocytes and the proximal tubule epithelial cells?
7:16 | Are there any specific medications being tested right now as potential treatments for these types of kidney diseases?
8:26 | For extracellular vesicles in general, what's their potential to be used as biomarkers for certain diseases? How could it be used in a clinical setting?
10:24 | Closing remarks
10:48 | Conclusion

Soundtracks by the Underground Drive. All rights reserved. Listen more: https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Hannah Deyell from the University of Ottawa interviews Dr. Adam Rudner on his current research and experience. Dr. Adam Rudner is an Associate Professor at the University of Ottawa in the Department of Biochemistry, Microbiology and Immunology, a member of the SEA-PHAGES and SEA-GENES programs, and the coordiantor of uOttawa Phage Hunters. The primary research focuses of Dr. Rudner's team are exploring the potential applications for baceteriophage therapy, building essential research skills, and exploring bacteriophages with interesting genomic sequences. In this episode, Dr. Rudner explores how bacteriophages can target antibiotic resistance for patients with disseminated bacterial infections, how his lab is working to increase the pool of available phages, and how personalized medicine can be used to improve patient outcomes with phage therapy.

Learn more: https://rudnerlab.med.uottawa.ca/Adam_Rudner_Lab/Home.html

00:00 | Introduction
01:00 | Dr. Adam Rudner's recent research focuses and ongoing projects
02:13 | The roles of bacteriophages and how they function to treat bacterial infections
03:04 | Advantages of bacteriophage therapy over tradtional antibiotics in the context of antibiotic resistance
04:13 | Challenges associated with research related to bacteriophages / limitations of bacteriophage therapy
05:44 | Primary motivators for using engineered bacteriophages as a treatment for 15-year old cystic fibrosis patient
07:51 | The purpose of engineering bacteriophages to effectively treat the patient
10:23 | The undergraduate SEA-PHAGES Program
11:48 | Dr. Adam Rudner's research advice to undergraduate students
13:17 | Conclusion

Credits for music: Soundtracks by the Underground Drive. All rights reserved. Listen more

https://music.apple.com/ca/artist/the-underground-drive/1571062779

https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Rama El Hakim from the University of Ottawa speaks with Dr. Doug Coyle, Professor at the University of Ottawa in the School of Epidemiology and Public Health. Listen in to learn about Dr. Coyle's recent work in CJC Open, which determines that lifesaving drug Canakinumab needs a cost reduction of 91% to be feasible in Canada.

Learn more: https://med.uottawa.ca/epidemiology/people/coyle-doug

00:10 | Introduction
01:41 | Dr. Coyle's Current Research Focuses
03:37 | Applications to Other Healthcare Systems
08:14 | Is the suggested 91% price reduction of Canakinumab feasible?
10:05 | Translating this research to clinical settings
11:05 | Advice to the general public
14:52 | Wrap-Up

Soundtrack by Secret Ops. All rights reserved. Learn more:

https://cctrax.com/mystified/secret-ops

https://creativecommons.org/licenses/by/4.0/

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In this special episode, Dr. Gabriela Ghisi talks about the educational component and its impact on cardiac rehabilitation, the challenges of cardiac rehabilitation programs across the globe, and the advancements of the International Council of Cardiovascular Prevention and Rehabilitation.

Learn more: https://kite-uhn.com/scientist/gabriela---melo-ghisi

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Spinal Muscular Atrophy (SMA) is a devastating genetic disease that causes muscle weakness and atrophy (shrinking of muscles) in children. There is currently no cure for this disease; however, base editing, a type of gene therapy, provides potential. Dr. Rasthmi Kothary is the Deputy Scientific Director and Senior Scientist at the Ottawa Hospital Research Institute. His lab focuses on understanding the mechanisms that underlie muscle and nervous system integrity. In this episode, Dr. Kothary gives us a greater insight on what SMA is, how it is currently being treated, and his research so far on a new base editing system to potentially cure this disease.

Episode produced & hosted by: Nicole Chu

Learn more: https://www.ohri.ca/profile/rkothary

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Jinane E. from the University of Ottawa interviews Dr. Mete Civelek, a distinguished researcher and professor in the department of biomedical engineering at the University of Virginia. Dr. Civelek’s research focuses on studying the complex interactions between genes and the environment that increase the risk of heart disease and type 2 diabetes. Dr. Civelek and his team employ cutting-edge bioinformatics tools to unravel the molecular pathways associated with these diseases and to develop personalized medicine strategies for cardiovascular and metabolic disorders. If you’ve ever been curious about computational biology applied to gene expressions, this episode is a unique opportunity to gain insights. Dr. Civelek provides an in-depth exploration of his research in systems genetics aimed at understanding cardiometabolic diseases.

Learn more: https://civeleklab.org/

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Nicole Chu from the University of Ottawa speaks with Sarah Groom, a Life Sciences recruitment professional and leader of the Pharmaceutical & Life Sciences recruitment division at Groom & Associates. Sarah holds Bachelor’s and Masters degrees in medical chemistry from the University of Ottawa. In this episode, Sarah gives us an introduction of GROOM, Canada’s leading recruitment firm, and shares some advice for recruitment. 

Learn more: https://www.groomassocies.com/about/

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Nicole Chu from the University of Ottawa speaks with Dr. Michael Laflamme, a Senior Scientist at the McEwen Stem Cell Institute in the University Health Network in Toronto. Dr. Laflamme holds the Robert McEwen Chair in Cardiac Regenerative Medicine and the Tier 1 Canada Research Chair in Cardiovascular Regenerative Medicine. In this episode, he speaks on the development of novel therapies for post-myocardial infarction heart failure based on human pluripotent stem cells.

Learn more: https://www.uhn.ca/Research/Research_Institutes/McEwen_Stem_Cell_Institute/Research/Pages/Michael_Laflamme.aspx

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Nicole Chu from the University of Ottawa speaks with Dr. James Fang, Chief of Cardiovascular Medicine at the University of Utah School of Medicine. Dr. Fang completed Cardiovascular Medicine and Advanced Heart Failure/Transplant Cardiology fellowships at the Brigham and Women’s Hospital. In this episode, he gives us a closer insight into heart failure characterized by preserved ejection fraction.

Learn more: https://healthcare.utah.edu/find-a-doctor/james-c-fang

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Deyanira Hdez. del Tecnológico de Monterrey habla con el Dr. Argel Aguilar.  El Dr. Argel es profesor e investigador del departamento de Neurociencia de la Universidad de Carleton, Canadá. El laboratorio del Dr. Argel Aguilar, en la Universidad de Carleton, investiga los mecanismos moleculares que subyacen a los trastornos psiquiátricos y del neurodesarrollo. Usan una combinación de bioquímica, biología molecular, cultivo neuronal y modelos animales para entender cómo los factores de riesgo genético contribuyen a las enfermedades mentales. En este episodio, el Dr. Argel cuenta sobre sus motivaciones y experiencia adquirida a lo largo de este tiempo así como su investigación con los trastornos de depresión y del espectro autista.

Learn more: https://carleton.ca/neuroscience/profile/argel-aguilar-valles/

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Jinane Elhage from the University of Ottawa interviews Dr. Soheila Karimi from the University of Manitoba. Dr. Soheila Karimi a Professor at the University of Manitoba in the Department of Physiology and Pathophysiology and the founding director of the Manitoba Multiple Sclerosis Research Centre. The primary research focuses of her team include the development of innovative therapies to treat debilitating neurological conditions such as multiple sclerosis and spinal cord injury. Are you curious about translational discoveries in neural regeneration and stem cell therapies? In this episode, Dr. Karimi shares more details regarding her research in neural injury regeneration, spinal cord injury, multiple sclerosis, and stem cell therapies.

Learn more: https://home.cc.umanitoba.ca/~karimis/

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Nicole Chu from the University of Ottawa interviews Dr. Edana Cassol from Carleton University. Dr. Edana Cassol is an Associate Professor in the Department of Health Sciences at Carleton University. She is also the Co-Director of the newly established Tissue Engineering and Applied Materials (TEAM) Hub. Her research team investigates the role of cellular metabolism in regulating macrophage function in response bacteria and viruses, and how these processes different across diverse tissue microenvironments. In this episode, Dr. Cassol shares with us more about the ongoing projects in her laboratory and highlights the interactions between infectious diseases and our body's immune system. 

Learn more: https://www.cassollab.com/

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In this special episode, Dr.Vasconcelos talks about cell therapy in heart disease, the challenges of developing effective treatments for diabetes, and the use of heart-on-a-chip technology, along with important advice for future researchers! 

Learn more: http://www.vasconceloslab.com

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Neste episódio especial, o Dr. Vasconcelos fala sobre terapia celular em doenças cardíacas, os desafios de desenvolver tratamentos eficazes para diabetes e o uso da tecnologia 'heart-on-a-chip', além de conselhos importantes para futuros pesquisadores!

http://www.vasconceloslab.com

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Nicole Chu from the University of Ottawa interviews Dr. Connor Kupchak from Carleton University. Dr. Connor Kupchak, an Assistant Professor at Carleton University in the Department of Electronics and leads the Carleton University Quantum Information Technology (cuQIT). The main research focuses of his team include the development of light-based quantum communication technologies for applications in the future quantum internet. Have you been curious to learn more about Quantum entanglement, which won the 2022 Nobel Prize in Physics? In this episode, Dr. Kupchak shares more details regarding his research in quantum optics, quantum entanglement, and applications in developing quantum-based technologies.

Learn more: https://doe.carleton.ca/~connorkupchak/

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刘明耀教授是多伦多总医院研究所资深科学家,多伦多大学外科教授. 他担任多个领导职务,包括医学院 医学科学研究所 所长和研究生院副院长。刘教授擅长对于急性肺损伤的细胞分子研究.在这期节目中,刘教授讲授成功经验那就是对科学永不放弃,一定会为社会做出贡献!

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Kieran Chalmers from the University of Ottawa interviews Dr. Michael De Lisio from the Department of Cellular and Molecular Medicine at the University of Ottawa, discussing the regenerative benefits of exercise. Dr. De Lisio is an associate professor at the University of Ottawa and runs the Exercise is Regenerative Medicine Lab where they investigate the effects of a lifestyle of exercise on disease recovery. Dr. De Lisio shares how exercise may reduce cancer risk, what is considered exercise, and the future of exercise in cancer treatment.

Learn more: https://www.delisiolab.ca/ 

Kieran Chalmers (Host), Catherine Leclerc (Content Generation), Sarah Lapolice (Producer), Nathan Joyce (Post-Production)

0:11 - Introduction
1:41 - How exercise is regenerative medicine
3:02 - Overview of Dr. De Lisio’s 2021 paper findings on the impacts of exercise on cancer-free survival and health span
9:12 - What is exercise?
10:56 - Future Directions

Soundtrack by the Underground Drive. All rights reserved. Listen more
https://music.apple.com/ca/artist/the-underground-drive/1571062779
https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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TMM student Rohan Ray interviews professor and scientist Dr. Michele Ardolino at the Ottawa Hospital Research Institute. Dr. Ardolino is an immunology expert and is highly established in this field, with many publications in top scientific journals. One of his studies that is discussed in this podcast is leukemia. In leukemia, a theft between cells called trogocytosis equips blood cancer cells for victory against the immune system. 

Learn more: https://www.ohri.ca/profile/mardolino

Ragav Chona (Content Generation, Editor & Producer), Alyanna Popatia (Content Generation & Producer), Rohan Ray (Voice), Salman Abdisalam (Pre-Production) 

00:48 - What sparked Dr. Ardolino's interest in the field
06:14 - Dr. Ardolino's explanation of trogocytosis
10:32 - Credits that thinking and luck is needed for new discoveries!
13:15 - Collaboration is key!

Soundtrack by Oleksii Kaplunskyi (LesFM) all rights reserved. Listen more https://bit.ly/2Jr35tF https://spoti.fi/2L952eF

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Melanie Kirkby from the University of Ottawa interviews Dr. Corinne Berger, a post-doctoral researcher at the University of Saskatchewan. Dr. Berger has a bachelor's degree in psychology and English literature, a master's degree in health and medical psychology, and a Ph.D. in neuropsychology. She was previously a post-doctoral fellow in informational/psychological warfare at Ariel University. In this episode, Dr. Berger shares her research on the use of Moxo d-CPT, a computer-based test that can detect ADHD, to determine if someone is feigning their ADHD diagnosis. We discuss the Moxo d-CPT, the research study that was conducted, its promise, and its limitations as of today. 

Learn more: https://www.usask.ca/

Melanie Kirkby (Voice), Zeynep Cildir (Post-production), Kieran Furlong (Producer), Naomi Tecle (Content developer).

0:00 - Introduction to Dr. Corinne Berger and their research into feigned ADHD
2:53 - How Dr. Berger became interested in ADHD research
3:50 - Research Background: What is Moxo-d-CPT, and does it detect ADHD?
7:30 - Research Design: How Moxo-d-CPT was evaluated to detect 'feigned' ADHD
10:35 - Research Results: Was Moxo-d-CPT successful in detecting feigned ADHD?
12:21 - The future uses of Moxo-d-CTP and ADHD research
13:05 - Conclusion and Thanks

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Meghana Kesanakurti from the University of Ottawa interviews Dr. Sandra Ramirez. Dr. Ramirez is a Senior Development Scientist in the Process and Products Development Group at the Centre for Innovation. She is also the head of the microbiology laboratory at Canadian Blood Services and an Adjunct Professor at the University of Ottawa. In this episode, Dr. Ramirez shares her research on the survival and threat of bacteria such as Staphylococcus in donated blood and how her work addresses this danger.

Learn more: https://med.uottawa.ca/bmi/en/people/ramirez-arcos-sandra

Meghana Kesanakurti (Voice), Meghana Kesanakurti, Sanjeevani Kumar, Natasha Strong, Katia Koziel Ly (Post-production, Content generation, Producers)

0:05 | BEaTS and host introduction.
0:32 | Introduction to Dr. Ramirez.
1:15 | What is Dr. Ramirez's research on blood contamination, and why is it important?
2:35 | Current issues with blood contamination.
3:47 | How bacteria survive in stored blood.
5:30 | What are complements and neutrophils?
6:34 | Why Dr. Ramirez studies Staphylococcus.
8:12 | Systems in place to prevent blood contamination and some of the issues we have with these methods.
11:05 | What issues are being addressed with Dr. Ramirez's future research?
12:17 | Will be able to eliminate bacteria from blood components completely?
14:02 | Conclusion

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Laila Alfadhli from the University of Ottawa's Translational and Molecular Medicine program interviews Dr. Mary-Ellen Harper. Dr. Harper is the university research chair in mitochondrial bioenergetics, director of the Metabolomics Advanced Training and International Exchange (MATRIX) program, and director (Interim) of the Ottawa Institute of System Biology. In this episode, Dr. Harper provides a general overview of the research conducted in her lab, discusses translating mechanistic research to clinical conditions, and gives insight into why she wrote some of her research articles.

Learn more: https://www.theharperlab.com/

This episode is brought to you by students from the 2023 Translational and Molecular Medicine cohort at the University of Ottawa. Laila Alfadhli (voice), Naveed Shahzada (Producer), Omar Ferri (content generation), Abdulla Al Aidie (post-production), and Celine Fawagreh (capsule design and voiceover).

1:11 - General overview of The Harper Lab's research
3:01 - Metabolic terminology: What's in the name?
7:50 - Factors affecting weight loss variability in obesity
11:25 - Explaining how oxidative fibers play a role in weight lose variability to the general public
12:50 - Appealing factors of metabolic research

Background music: Smarties Intro - FMA Podcast Suggestion by Birds for Scale, licensed under an Attribution-ShareAlike 4.0 International License https://freemusicarchive.org/music/birds-for-scale/smarties/smarties-intro-fma-podcast-suggestion/.

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Chantal MacLean, a Translational and Molecular Medicine student at the University of Ottawa, interviews Dr. Stephanie Willerth. Dr. Willerth is a Full Professor and Canada Research Chair in Biomedical Engineering at the University of Victoria. She also currently serves as the Acting Director of the Centre for Biomedical Research at the University of Victoria. In this episode, Dr. Willerth discusses her research using 3D bioprinting to print brain tissue and what inspired her to enter this exciting research field.

Learn more: https://www.engr.uvic.ca/~willerth/

Chantal MacLean (Voice), Alexandra Akman (Post-production and Content generation), Emma Dorfman (Producer)

0:30 - Background: science fiction to reality!
0:55 - Intro to Dr. Willerth
1:34 - Main research question
2:43 - What is a bioink?
3:40 - Benefits of 3D bioprinting
4:25 - Why is viability so important to tissue engineering?
6:00 - Properties of bioprinted tissues
8:03 - Applications of bioprinted tissues in clinic
9:29 - Future directions
10:10 - Bonus: inspiration behind Dr. Willerth's field of study

Soundtrack provided by the Underground Drive all rights reserved.
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Today's podcast features an interview with uOttawa's very own Dr. Nicolas Bordenave, a nutrition and food sciences researcher! Today we will be busting the long-told tale of eating your greens...as we will discover, eating your veggies is not always good for you! To learn more about this fascinating discovery, tune in to this episode!

Learn more: https://med.uottawa.ca/bmi/en/people/bordenave-nicolas

Episode produced by Arpana Wadhwani, Amanie Salama, and Alicia Wu

1:02 - Intro to Dr. Bordenave and His Research 
3:00 - Explaining Beta-Glucans and Phenolic Compounds … Why are they important? 
6:56 - The importance of viscosity 
9:07 - Important conclusions of the study 

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Andrea Corrales-Malaga, Stephanie Lofaro, and Valeria Vasilyeva from the University of Ottawa speak with Dr. Payal Arya, a postdoctoral fellow in the Gobes laboratory in the Department of  Neuroscience at Wellesey College. Tune in to learn more about their recent work published Neuroscience letters, which demonstrates that the brain's left hemisphere plays the dominant role in auditory learning. 

Learn more at: http://academics.wellesley.edu/Neuroscience/gobes/home.html. 

Andrea Corrales-Malaga (voice), Stephanie Lofaro (post-production), Valeria Vasilyeva (content generation) 

1:00 - Ongoing projects in the Gobes laboratory and Dr. Arya's current research focus 
2:20 - Zebra finches as the researched animal model 
4:00 - Neurological and behavioral differences in male vs. female zebra finch vocalizations
4:46 - Bilateral brain activity publication key findings and hemispheric asymmetry introduction
6:28 - Use of fathers vs. tutor finch substitutes 
7:08 - Techniques and technologies used to achieve results 
9:04 - Song acquisition and speech learning comparison to humans 
10:45 - Evolutionary advantage of neural processing as improved by hemispheric asymmetry 
12:37 - Knowledge application and future directions 

Soundtrack from https://youtu.be/ZpveW5nptkE. 

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Ciara Hefferman from the University of Ottawa interviews Dr. Leila Mostaço-Guidolin. Dr. Mostaço-Guidolin researches optical microscopy and image analysis with 3-D bioprinting as an Assistant Professor in the Systems and Computer Engineering department of Carleton University. In this episode, you will learn about atherosclerosis and its importance in human health and heart attacks. Dr. Mostaço-Guidolin will also use their expertise to educate you on what non-linear optical microscopy is, how it can track the progression of atherosclerosis and what her team has been researching about this technology.

Learn more: https://carleton.ca/mostacoguidolin/

Walid Hassouni (Producer + coordinator), Marissa Hamlin (Scientific writer + graphic design creator), Sebastian Gaudette (Host + audio editor), Ciara Hefferman (Host)

0:00 - General introduction/hook
0:26 - BEaTS Research Radio introduction and synopsis of podcast
1:14 - Description of atherosclerosis
3:21 - Description of nonlinear optical microscopy (NLOM)
3:54 - Introduction to Dr. Mostaço-Guidolin and her research
4: 40 - What is NLOM, why is it useful and what do we need to change for clinical use?
9: 06 - Understanding of extracellular matrix proteins and components
12:42 - Outro/conclusion

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Tanvi Ahluwalia (voice), Chelsea Klein (post-production), and Amanda Bruce (post-production) from the Translational Molecular Medicine program at the University of Ottawa interview Ph.D. student Rafael Silva Lima from the Cell-Cell Interaction Lab at the Federal University of Minas Gerais in Belo Horizonte, Brazil. Rafael works on the characterization of the intestinal microbiota and the expression and methylation profile in CD4 + T cell differentiation genes in childhood and juvenile obesity. In this episode, Rafael shares with us his research on COVID-19 and how obesity interplays with the immune system to foster a severe immune response and contribute to severe COVID-19. 

Learn more: https://labicufmg.wixsite.com/labic/alunos?lang=en 

0:00 - Introduction
1:30 - What is covid-19?
5:00 - How does obesity provide higher susceptibility to COVID-19 symptoms?
6:15 - Immunology & Obesity Research
7:15- Why obesity?
8:00 - How did you select papers for the review? 
9:00 - Upregulated Genes in Obesity
10:30 - Next steps in obesity research & COVID-19 research
12:15 - Differences in immune response between COVID-19 variants

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Sabrina Gregoire, a student at the University of Ottawa, interviews Dr. John Bell on behalf of her team for the TMM4950 Science Communication Course. Dr. Bell is a Senior Scientist in the Cancer Therapeutics Program at the Ottawa Hospital Research Institute. He is also the program director of the Canadian Oncolytic Virus Consortium and a Professor in the Departments of Medicine and Biochemistry, Microbiology, and Immunology at the University of Ottawa. In this episode, Dr. Bell discusses his research interests and ongoing projects, how cancer-killing viruses work, the advantage of this therapeutic strategy over conventional methods, and its potential for translation into clinical treatment.

Learn more: https://www.ohri.ca/profile/jbell

Sabrina Gregoire (Voice, Content generation), Sandra Fang (Post-production, Content generation), Marcelle Mackenzie (Content generation), and Floriana Maswa (Content generation).

1:02 - Research interests and ongoing projects
4:18 - How oncolytic viruses differentiate between healthy and cancerous cells
6:43 - Using the prime + boost technique in anti-cancer vaccines
9:07 - Co-administrating peptide with oncolytic viruses vs. Engineering oncolytic viruses to encode peptide
10:50 - Advantage of oncolytic viruses over conventional methods
12:48 - Clinical translation of oncolytic viruses

Soundtrack by the Underground Drive. All rights reserved. Listen more: https://music.apple.com/ca/artist/the-underground-drive/1571062779 https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Aaron Gallardo from the University of Ottawa speaks with Dr. Arvind Mer, Assistant professor at the University of Ottawa in the Department of Biochemistry, Microbiology, and Immunology. Dr. Mer’s lab uses cutting-edge machine learning and artificial intelligence methods for genomic data mining and advancing personalized medicine. Tune in to learn more about his recent work using AI and machine learning to characterize subtypes of acute myeloid leukemia. 

Learn more: https://merlab.github.io/

Produced by: Adela Gottardi and Rachel Piché

0:05  - Introduction/Welcome to Dr. Mer 
1:05 - What is the main focus of your research?
2:30 - What inspired you to enter this field of research?
3:26 - Can you briefly describe machine learning/AI for our audience?
7:01 - Can you describe your labs discovery and research regarding NMP1 and leukemia?
9:30 - How important was the role of machine learning in making these discoveries?
10:34 - What are the next steps/directions for your lab?
12:19 - How can people learn more about your lab and get involved in this research?
13:25 - Thank you to Dr. Mer!

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Philippe Corbin (Voice) from the University of Ottawa speaks on behalf of his team, Kassandre Kelly (Post-production) and Dalia Frank Kamenetski (Content generation), to Dr. Leila Mostaço-Guidolin, Assistant Professor at Carleton University within the Department of Systems and Computer Engineering. 

Join us as we learn more about their research on airway remodeling in Asthma patients using 3D bio-printing and non-linear optical microscopy, which they published in the American Journal of respiratory and critical care medicine in 2019. 

Learn more: https://carleton.ca/mostacoguidolin

0:55 | Introduction to the topic
3:23 | Challenges of Bioprinting
6:00 | The significance of studying collagen with non-linear microscopy
7:36 | The advantages of using the non-linear microscope 
8:48 | Findings that demonstrated that there is collagen disorganization in asthma
10:35 | The significance of the decrease of decorin in asthma
13:20 | Developments of this project since the publication of this article
14:24 | Conclusion and Acknowledgments

Soundtrack by the Underground Drive all rights reserved. Listen more https://music.apple.com/ca/artist/the-underground-drive/1571062779 or https://open.spotify.com/artist/4sCJG8TMQyTZ9FDd1JjJmR

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Up to one billion people, nearly 1 in 6 of the world's population, suffer from neurological disorders, many of which are only diagnosed when it is too late for medical intervention. Join us for this episode, where we will delve into a fascinating discussion of a novel brain imaging technique that can detect early stages of psychiatric disorders, potentially even before symptoms appear.

Learn more: https://www.cliffordcassidy.com/ 

Leen Madani (Content generation), Sumaya Alsayadi (Content generation), Danya Alomar (Post-production), Isabella Zabek (Voice)

0:28 - Guest introduction
1:15 - What got you interested in what you do?
2:37 - Research focus and ongoing projects
4:19 - MRI vs. neuromelanin MRI: How are they different?
6:19 - What is neuromelanin doing in our brain?
8:00 - What does dopamine mean to you?
10:15 - Putting it all together
12:28 - How can we use this tool as a marker of different illnesses?
14:06 - Wrap up

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BEaTS Research Radio is happy to present our latest episode, where Ibrahim Alayche, a student studying Translational and Molecular Medicine at the University of Ottawa, conducts an extensive interview with Dr. Errol Thomson, a Research Scientist and Adjunct Professor at the University of Ottawa, Environmental Health Science and Research Bureau, and Health Canada. Dr. Thomson's research heavily emphasizes the negative effects of air pollution on our overall health, and he is recognized for his important contributions to this field. Our episode today with Dr. Thomson focuses on his latest research that provides an interesting perspective in regards to how traffic air pollution can have a significant negative impact on our stress levels, specifically on how diesel exhaust causes changes in our cortisol levels, a hormone produced exclusively to deal with stressful situations. Tune in to learn more about how he and his team studied these effects and what we can do to protect ourselves in the future better!

Learn more: https://med.uottawa.ca/bmi/en/people/thomson-errol

Ibrahim Alayche (Voice & Post-production), Giorgio Freije & Carlos Rios Giraldo (Content generation), Ruiyan Gao (Producer)

1:19 - What is traffic-related air pollution?
2:12 - How would you define stress? Can you measure it?
3:27 - Air pollution as a stressor
4:00 - Goal of the study
5:15 - Methodology and study design
8:56 - Results of short exposure to diesel exhaust on cortisol levels
10:06 - Health implications of having high cortisol levels from traffic-related air pollution
11:02 - Should we be worried about the results?
11:35 - General recommendations
12:39 - Future studies on traffic-related air pollution

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Dylan Thomas from the University of Ottawa interviews Dr. Maria Isabel Carreño-Muñoz. Dr. Carreño-Muñoz is a post-doctoral student in Dr. DiCristo's Lab at the CHU Sainte-Justine Research Center, affiliated with Université de Montréal. In this episode, Dr. Carreño-Muñoz shares her research on developing a new tool for behavioral analysis called Phenotypix. Here she elaborates on this exciting technology which has the potential to analyze aspects of animal model behavior that have previously been out of reach to researchers.

Learn more: https://research.chusj.org/en/Home

Dylan Thomas (Voice and Post-Production), Michelle Gandelman (Pre-Production and Graphic Design), Jess Hursti (Pre-Production and Post-Production), Nik Chander (Pre-Production and Post-Production)

2:47 - What are piezoelectric sensors and how do they work?
4:27 - Identifying subtle behaviours in animal models with Phenotypix
6:05 - Using Phenotypix to detect new behaviours in mouse models of Fragile-X Syndrome
7:49 - Measuring heart rate in a new, non-invasive manner
10:27 - Applications of this technology in different fields 

Soundtrack by the Underground Drive. All rights reserved. Listen more:
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Shafik and Rachel from the University of Ottawa interview Dr. Manoj Lalu. Dr. Lalu is an associate scientist from the Ottawa Hospital Research Institute and an associate professor at the University of Ottawa. He is also a co-leader of the Blueprint team, a research team aiming to improve the translation of preclinical to clinical research. Dr. Lalu is with us today to discuss his ongoing research monitoring the first Canadian multicentric preclinical study investigating a wide range of treatments against sepsis. Dr. Lalu shares with us his discoveries on the factors that can help preclinical scientists work with other labs successfully. 

Learn more: https://www.ohri.ca/profile/mlalu 

Shafik Algharbi (Voice), Rachel Friesen (Voice), Arvin Zaker (Post-production), Osama Mahdi (Post-production)

00:00 - Introduction
03:01 - Description of the research
03:48 - Existing barriers of multi-centric research
05:49 - Benefits of multi-centric research
07:33 - The thing that surprised Dr. Lalu in his study
09:07 - Drawbacks of multi-centric research
10:07 - Suggestions for scientists
11:14 - Outro

Music by Coma-Media from Pixabay

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Malithi Thanthridge (Voice, Content generation), Ishika Tripathi (Content generation), and Julie Pan (Post-production, Content generation) from the University of Ottawa interview Dr. Zen Faulkes. 

Dr. Zen Faulkes is a scientist and Assistant Professor at McMaster University and the well-renowned author of several books, blogs, and papers on topics including neurobiology, carcinology, evolutionary biology, and scientific communication. In this episode, Dr. Faulkes shares with us the issues surrounding the crayfish pet trade ecologically and legislatively and proposes ways to improve them. 

Learn more: https://sites.google.com/site/doctorzen/home?authuser=0&pli=1

0:30 - Introducing the researcher: Dr.Zen Faulkes 
1:01 - Summary of two papers discussed
1:34 - Discussing the problem at hand: invasive crayfish
9:15 - Challenges of this project and next steps - finding information and encouraging action
12:51 - Overall Summary and what you can do to help

Soundtrack by the Underground Drive. All rights reserved. Listen more 
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Amanda Featherstone from the University of Ottawa interviews Dr. Simon Matoori, an assistant professor at l’Université de Montréal, Faculté de Pharmacie. He is also a federally licensed pharmacist in Switzerland where he completed his PhD in Drug Formulation and Delivery at ETH Zurich. He later completed his postdoctoral studies in Bioengineering at Harvard University. Dr. Matoori's lab is developing a novel diagnostic tool for the early detection of sepsis.

Learn more: www.matoori-lab.com

This special episode was written by Ana Radar (Post-production, Content generation), Jinane Elhage (Post-production, Content generation), Ella McIlroy (Content generation), and Amanda Featherstone (Voice, Content generation, Post-production).

0:56 - Introduction and the main focus of Dr. Matoori's research.
2:30 - The need for improved sepsis diagnosis.
6:40 - Methods for developing the diagnostic assay.
8:28 - How does this two-step reaction assay effectively diagnose sepsis?
10:05 - Plans for translating the assay into the clinic.
12:53 - The biggest potential advantage of the assay in sepsis detection.
14:03 - The potential for nanomedicine, and this assay specifically, in global access.
15:37 - Final acknowledgments.

Soundtrack by the Underground Drive. All rights reserved. Listen more:
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The Immunotmetabolab team led by Dr. Morgan Fullerton at the University of Ottawa was able to find a breakthrough in discovering a novel signaling pathway involving the AMPK-HMGCR axis associated with regulating cholesterol levels and the development of atherosclerosis. This was achieved using atherosclerotic-prone mice to demonstrate that disrupting AMPK regulation of HMGCR leads to increased aortic lesion size, lipid accumulation, circulating cholesterol, and plaque-associated macrophages. Additionally, these mice exhibited increased atherogenic monocytes associated with the increased intracellular cholesterol in hematopoietic stem and progenitor cells. With this discovery, the Immunometabolab team continues to demonstrate the importance of the interaction between the immune and metabolic systems. Their findings will facilitate the development of new therapies for targeting atherosclerosis and help prevent the onset of myocardial infarction and stroke.

Learn more: https://www.fullertonlab.com/

Team: Athavan Murugaananthan (Voice), Ammar Alam (Content generation), Aditya Prashar (Content generation), Nicolas Toex (Post-production and Producer)

0:16 Introduction
1:15 How are metabolic and immune pathways linked, and why are you interested in this research?
2:47 What are AMPK and HMG Coa Reductase, and what role do they play in our body?
5:34 Some of the results (blocking AMPK signaling leads to the development of atherosclerosis) that you were able to find?
8:01 Do you think that there are other pathways that could be significant in the development of atherosclerosis?
9:59 What is the significance of your research, and are there any drugs in clinical trials that revolve around it?
11:47 Conclusion

Credits for music: "Soundtracks by the Underground Drive. All rights reserved. Listen more

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Deyanira Hdez. del Tecnológico de Monterrey, habla con la Dra. Grissel Trujillo de Santiago. La Dra. Trujillo es profesora e investigadora de la Escuela de Ingeniería y Ciencias del Tecnológico de Monterrey y una de los Investigadores líderes de Álvarez-Trujillo Lab. En este episodio la Dra. Trujillo explica sobre qué es su investigación, específicamente sobre su tecnología de impresión caótica en 3D, así como su experiencia como Investigadora Principal del Laboratorio Álvarez-Trujillo; de igual manera, nos cuenta sobre sobre su motivación y los retos que se le han presentado a lo largo de su carrera. 

Mas información: https://alvareztrujillolab.com/index.html

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Nicole Chu from the University of Ottawa interviews Dr. Duncan Stewart. Dr. Stewart serves as the CEO and Scientific Director of the Ottawa Hospital Research Institute, and the Executive Vice-President of Research at The Ottawa Hospital. He is also an active senior scientist in The Ottawa Hospital’s Regenerative Medicine Program who holds the Evelyne and Rowell Laishley Chair and is a Professor in the Department of Medicine at the University of Ottawa. Dr. Stewart is recognized as a pioneering Canadian cardiovascular researcher for his discoveries in blood vessel biology. In this episode, Dr. Stewart shares with us his research, his ongoing clinical trials, and his focus on translating benchside research into clinical treatments for patients. 

Learn more: https://www.ohri.ca/profile/DuncanJStewart

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Nicole Chu from the University of Ottawa speaks with Dr. Sophie Lerouge. Dr. Lerouge is a Full Professor in the Department of mechanical engineering at École de technologie supérieure (ÉTS) and Adjunct Professor at the University of Montreal. She is also a Principal Scientist at the CHUM Research Centre in Montreal, Quebec and was the Canada Research Chair on endovascular implants and biomaterials from 2008 to 2018. In this episode, Dr. Lerouge shares with us her research on the design and evaluation of new biomaterials, such as hydrogels, and how her team optimizes their qualities for applications in vascular diseases, cell therapy and tissue engineering. 

Learn more: https://www.etsmtl.ca/en/research/professors/slerouge/

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Nicole Chu from the University of Ottawa speaks with Professor Cooper. Professor Cooper was elected as a Fellow of the Royal Society in 2015 and is currently a Professor of Chemistry at the University of Liverpool. He is the Founding Director of the Centre for Materials Discovery and the Academic Director of the new Materials Innovation Factory. He is also the principal investigator of the Cooper Group at the University of Liverpool, and his pioneering research work in Materials Chemistry focuses on polymer synthesis, nanoparticles and crystal engineering. In 2011, he was named one of the Top 100 materials scientists of the last decade in the Thomson Reuters list. In 2021, he was awarded the Super AI Leadership award, which was previously won by IBM Research, for his robotics work on the mobile chemist that was published in the Journal Nature. In this episode, he joins us to discuss more about the topic of AI in materials chemistry. Learn more: https://www.liverpool.ac.uk/cooper-group/

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Nicole Chu from the University of Ottawa speaks with Dr. Adam Shuhendler, an associate professor at the University of Ottawa and a Canada Research Chair (Tier 2) in Chemical Biology. He is also cross-appointed to the UOHI, and is affiliated with the University of Ottawa Brain and Mind Research Institute where he is a member of the Concussion Injury Group. In this episode, Dr. Shuhendler shares how his team at the Molecular Medicine Lab is optimizing medical imaging technologies such as PET and CEST-MRI to screen for diseases on a molecular level. 

Learn more: https://www.molmedlabuo.com/

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渥太华大学的褚慕佳采访李剑宇教授。李教授毕业于浙江大学,并获得哈佛大学机械工程博士。他现任McGill University (麦吉尔大学) 机械工程系助理教授以及加拿大生物材料,肌肉骨骼健康的研究主席。在这期采访中,李教授介绍了他团队做的生物材料研究 以及新一代的止血技术研究和应用。 

https://sites.google.com/view/libiomater/home 

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Nicole Chu from the University of Ottawa speaks with Dr. Darlene Kitty. Dr. Kitty is a Cree woman and family physician who has been practicing since 2006 in Chisasibi, the largest of 9 Cree communities in northern Quebec. In this episode, she highlights the importance of curiosity, care, and mentorship on her journey to becoming a physician, and shares with us areas of advocacy to improve Indigenous health and cultural safety. 

Learn more: https://fafm.cfpc.ca/darlene-kitty/

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Dr. Gomes fala sobre a importância de desenvolver novos catalisadores, novas abordagens para representar estruturas moleculares com gráficos e o que podemos esperar do machine learning na química e engenharia.

https://gomesgroup.andrew.cmu.edu/index.html

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Dr. Gomes talks about the importance of developing new catalysts, new approaches to representing molecular structures with graphs, and what we can expect from machine learning for chemical and engineering applications.

https://gomesgroup.andrew.cmu.edu/index.html

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Nicole Chu from the University of Ottawa speaks with Dr. Filipa Simões, a Principal Investigator and British Heart Foundation Intermediate Basic Science Fellow at the Institute of Developmental and Regenerative Medicine in the University of Oxford. In this episode, Dr. Simões shares with us how her passion for science began, her research with zebrafish models, and how her team is investigating the function of macrophages in heart regeneration post-heart attack. 

Learn more: https://www.idrm.ox.ac.uk/research/cardiology/cardiology-research-groups/simoes-group

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Heart Valve Diseases (HVD) is being described as ‘the next cardiac epidemic’. In support of Heart Valve Awareness Week 2022 (Sept 12-18) and the #ListenToYourHeart Campaign, this discussion highlights the diagnosis stories of 3 unique individuals and aims to bring awareness to the importance of regular screening and early diagnosis. Heart valve disease: It’s common, serious, but treatable. 

For more information on the Listen to Your Heart Campaign, please visit: 
https://www.heartvalvevoice.ca/listen-to-your-heart 

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Deyanira Hdez. de la Universidad de Ottawa habla con el Dr. Sergio Lavandero. El Dr. Lavandero es un científico chileno muy bien establecido que ha recibido reconocimiento tanto nacional como internacional. El Dr. Lavandero mantiene una posición de profesor adjunto en la División de Cardiología en University of Texas Southwestern Medical Center; también es Director e Investigador Principal del Centro Avanzado de Enfermedades Crónicas (ACCDiS ). En este episodio el Dr. Lavandero explica sobre qué es su investigación y su experiencia como director de dicho centro; de igual manera cuenta sobre su experiencia como profesor. 

Para saber mas, visita https://www.accdis.cl/eng/en/sergio-lavandero/

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Nicole Chu from the University of Ottawa speaks with Dr. Mike Hildebrand, Associate Professor at Carleton University in the Department of Neuroscience and Affiliate Investigator at the Ottawa Hospital Research Institute. Tune in to learn more about their recent work published in the Journal Brain which demonstrates for the first time that spinal cord process pain signals differently in women compared to men. 

Learn more: https://hildebrandpainlab.com/ 

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Disclaimer: The views and opinions expressed in this radio episode are those of the speakers and do not necessarily reflect the views or positions of the UOHI, University of Ottawa, or BEaTS Radio affiliates.

BEaTS Research Radio aims to provide a platform for leaders and scientists across the globe to disseminate their research. Russia’s invasion on Ukraine has affected millions of innocent Ukrainians, including scientists. This episode invites a Faculty member from the University of Ottawa community and two early-career Ukrainian graduate students to share their experiences and the resources they found helpful in supporting scientists from Ukraine.

Valeriia Kolesnyk is a former student of Kharkiv University of Radio Electronics who graduated with a Bachelor of Software Engineering in June 2022. She has experience working as a Business Analyst for almost 2 years in IT company. On the day war began, she was in Kharkiv and was woken up by the explosions.

Myroslava Volosheniuk is an international student from Ukraine who started her Master's Degree of Organic Chemistry in the Beauchemin Lab at the University of Ottawa in January 2021. In the last 8 years before coming to Canada, she was studying in Kyiv, but is originally from the Vinnytsia region.

Dr. Augusto Gerolin arrived in Canada less than one year ago to establish a research group at the University of Ottawa as a Canada Research Chair in Artificial Intelligence at the Interface of Chemistry and Mathematics. He is an Assistant Professor jointly appointed to the Department of Mathematics and Statistics and the Department of Chemistry and Biomolecular Sciences.

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Nicole Chu from the University of Ottawa speaks with Dr. Brokoslaw Laschowski, a Ukrainian-Canadian researcher working in the Temerty Faculty of Medicine at the University of Toronto and the Toronto Rehabilitation Institute. He is also the national coordinator for Canada for #ScienceForUkraine, a global initiative that provides resources and support to Ukrainian students and researchers who have been affected by the Russian invasion and war in Ukraine. In this episode, Dr. Lashowski speaks on his research on wearable robotic devices and how he became involved in an international initiative to help support Ukraine. Learn more: https://scienceforukraine.eu/ Website Dr. Laschowski: https://iatsl.org/people/blaschowski.html

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Ana S. from the University of Ottawa speaks with Dr. Paul Riley, the Director of the British Heart Foundation Oxbridge Centre for Regenerative Medicine. The focus of his research program is to investigate the potential that lies in activated resident cardiovascular cells in the development of treatments for cardiovascular regeneration. In this Curiosity Capsule, Dr. Riley discusses his role as the Chair of Development and Cell Biology at the University of Oxford and the Director of the newly established Institute of Developmental & Regenerative Medicine. 

Learn more: www.idrm.ox.ac.uk

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Nicole Chu from the University of Ottawa speaks with Dr. Kanika Harris, the Director of Maternal Health for the Black Women’s Health Imperative, public health expert for the DC Mayor’s Lactation Commission and the Maternal Health Equity advisor for the state of Maryland. In this episode, Dr. Harris speaks on her past research in South Africa, focusing on maternal health and HIV prevention. She also speaks on the Black Women's Health Imperative, their purpose, and how they are working towards eliminating the racial disparity which is still prevalent against Black women in healthcare.

Learn more: https://bwhi.org/

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Dr. Lara Gharibeh, uOttawa/Ottawa Heart Institute, interviews Dr. Giovanni Ferrari, an Associate Professor in the Department of Surgery and School of Biomedical Engineering, Columbia University, NY, USA. In this episode, Dr. Ferrari shares his unique experience as a researcher in Translational Science. He also reveals some of his research interests, his involvement in the Columbia tissue and blood biobank, and his important role in mentorship for early career professionals.

Learn more: www.ferrarilabcolumbia.com

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Dr. Nunes de Vasconcelos: In this Curiosity Capsule, Ana S. from the University of Ottawa speaks with Dr. Sara Nunes de Vasconcelos, a scientist in the Division of Experimental Therapeutics at the University Health Network and a Professor in the Institute of Biomedical Engineering at the University of Toronto. The focus of Dr. Nunes de Vasconcelos’ research programme is the generation of alternative therapeutic avenues to treat cardiovascular diseases. In this episode, Dr. Nunes de Vasconcelos discusses the development of the Biowire, a novel, innovative platform for maturation of human pluripotent stem cell-derived cardiomyocytes. 

Learn more: http://www.vasconceloslab.com/

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Dr. Lara Gharibeh, uOttawa/Ottawa Heart Institute, interviews Dr. Hanadi Sleiman, a Professor in the Department of Chemistry at McGill University, Canada. In this episode, Dr. Sleiman shares what inspired her to pursue her career journey in DNA nanotechnology. She also shares insights on her ground-breaking advancements in the field of DNA nanotechnology and precision medicine to combat major diseases.

Learn more: https://sleimangroup.com/

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Tuba B. from the University of Ottawa talks to Dr. Caroline Ménard a Professor in the Department of Psychiatry and Neurosciences at the Faculty of Medicine in the CERVO LAB at Laval University where she investigates the root causes of brain diseases. Most recently, Dr. Ménard led projects investigating the neurobiology of stress vulnerability and resilience and the development of mood disorders. In this interview, Dr. Ménard describes her research on biological measures that can help to establish a diagnostic test on mental health conditions such as anxiety and depression. She explains the connection between resilience/vulnerability to stress in the development of major depressive disorder (M.D.D.). Dr. Ménard reveals certain differences that men and women experience during depression. We discussed the reasons why some people respond poorly to current antidepressants and the causes for this resistance. Lastly, she provides her outlook on the future of mental health prevention and touches on ways to keep healthy

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Janis Petit discute avec Charlette N'Guessan, co-fondatrice de BACE API, un logiciel de vérification d'identité à distance utilisant la reconnaissance faciale alimentée par l'IA. Charlette est la première femme à remporter le prix africain d'ingénierie décerné par la Royal Academy of Engineering et a été reconnue comme l'une des 80 femmes africaines faisant progresser l'intelligence artificielle en Afrique et dans le monde. Elle est co-auteur de deux livres. Durant l'entrevue, Chalette nous parle de son logiciel BACE API, des utilisations actuelles de son logiciel et de son avenir. 

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Janis Petit talks with Charlette N'guessan, co-founder of BACE API, a remote identity verification software using AI-powered facial recognition. Charlette is the first woman to win the Africa prize of engineering awarded by the Royal Academy of Engineering and has been recognized as one of 80 African women advancing artificial intelligence in Africa and around the world. She is co-author of "the AI BOOK " published in 2020 and "Rising to the top Volume IV" published in 2022. In this interview, Charlette talks about "Rising to the top Volume IV", the purpose of this book, and why she wanted to be part of this amazing project. Charlette also talks about what drives her and keeps her motivated.

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Janïs Petit discute avec Myriam Valin, developeuse Logiciel chez Zimmer Biomet depuis plus de 15 ans. Myriam Valin a fait un baccalauréat en ingénierie informatique à l'université de Sherbrooke et une maitrise en ingénierie biomédicale à l'université de Montréal. Dans cette entrevue, Myriam Valin nous parle de la branche de chirurgie assistée par ordinateur de Zimmer Biomet, de l'utilisation de ROSA en salle d'opération et du future de la chirurgie assistée par ordinateur.

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Janïs Petit discute avec Myriam Valin, developeuse Logiciel chez Zimmer Biomet depuis plus de 15 ans. Myriam Valin a fait un baccalauréat en ingénierie informatique à l'université de Sherbrooke et une maitrise en ingénierie biomédicale à l'université de Montréal. Dans cette entrevue, Myriam Valin nous parle de son parcour académique et professionel, de son expérience en tant que femmes en génie logiciel, et donne des conseils aux jeunes filles intéressées à poursuivre des études en ingénierie et en sciences.

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Dr. Niv Ad, an internationally renowned leader in cardiothoracic surgery speaks to BEaTS Research Radio about why he decided to pursue a career in medicine and the key factors that aid in successful cardiac surgeries for patients worldwide.

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Nicole Chu from the University of Ottawa speaks with Dr. Annie Huang. Dr. Annie Huang holds a Tier 1 Canada Research Chair and is a Professor of Paediatrics with Laboratory Medicine and Pathobiology at the University of Toronto. She is also the Associate Chair of Research of the Department of Paediatrics at The Sickkids Hospital. Dr. Huang founded The Rare Brain Tumor Consortium (RBTC), an international network of physicians and scientists dedicated to improving the survival of children diagnosed with rare brain tumors. Tune in to this episode to learn more about how the RBTC brings families and researchers across the world together, sharing the common goal of making rare brain tumours a curable disease. 

Learn more: https://lab.research.sickkids.ca/annie-huang/rbtc/

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Nicole Chu from the University of Ottawa speaks with Dr. Xi Huang. Dr. Xi Huang is an Assistant Professor in the Faculty of Medicine, Department of Molecular Genetics at the University of Toronto, Senior Scientist at the SickKids Hospital and Tier 2 Canada Research Chair in Cancer Biophysics. Ion channels represent a large class of drug targets however their impact on brain cancer remains understudied. Tune in to this episode to learn more about the influence of mechanosensitive ion channels on brain tumours.

Learn more: https://lab.research.sickkids.ca/huang/

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渥太华大学的褚慕佳采访黄熹教授。黄教授是多伦多大学分子遗传学助理教授、加拿大多伦多大学附属儿童医院(SickKids)高级科学家,和加拿大癌症生物物理学研究主席。在这期采访中,黄教授解释了离子通道的机械性能及其在治疗脑癌和恶性肿瘤等方面的应用前景。 

https://lab.research.sickkids.ca/huang/

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Janis Petit de l’université d’Ottawa parle avec le Dr Georges Nemer, un professeur et coordinateur du programme de génomique et médecine de précision au collège de la santé et des sciences de la vie de l’université Hamad Bin Khalifa au Qatar. Dr Nemer a obtenu son doctorat en pharmacologie à l’université de Montréal en 2002. Dans cette entrevue, Dr Nemer parle de la médecine précision, de ces obstacles et de son avenir. Il parle aussi de l’importance de la collaboration en sciences.

Pour plus d’information sur Dr Nemer : https://www.hbku.edu.qa/en/staff/georges-nemer

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Ana S. from the University of Ottawa speaks with Dr. May Griffith, a Professor in the Department of Ophthalmology at the University of Montreal and a researcher at the Maisonneuve-Rosemont Hospital Research Centre. Her research focuses on cornea regeneration and the development of biomimetic biomaterials for regenerative medicine. In this Curiosity Capsule, Dr. Griffith discusses how she led her team in successfully regenerating the world's first human cornea using biosynthetic implants, how she is working towards solving the global problem of the shortage of human donor corneas, and her vision for the future of biomaterials engineering in Canada and beyond.

Learn more about Dr. Griffith’s work: https://www.griffithresearch.ca/

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Ana S. from the University of Ottawa speaks with Dr. Stephanie Willerth, a Professor and the Acting Director of the Centre for Biomedical Research at the University of Victoria. Dr. Willerth runs a research program investigating neural tissue engineering treatments for disorders of the central nervous system, while concurrently training highly qualified personnel. In this Curiosity Capsule, Dr. Willerth speaks about how her groundbreaking work combines stem cells, tissue engineering, drug delivery, and 3D bioprinting.

Learn more about Dr. Wilerth’s research https://www.engr.uvic.ca/~willerth/drwillerth.shtml

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Dr. Lara Gharibeh, uOttawa/Ottawa Heart Institute, interviews Mr. Hashem Al-Ghaili, a science communicator and a video producer based in Berlin, Germany. In this episode, Mr. Al-Ghaili shares what inspired him to pursue his career journey in science communication. He also shares insights on the challenges he faces, how he navigates misinformation, and where he sees the evolution of the field of science communication is going.

Learn more: https://hashem-alghaili.com/

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تقابل الدكتورة لارا غريبه ، معهد أوتاوا للقلب / أوتاوا ، السيد هاشم الغيلي ، متخصص في التواصلالعلمي ومنتج فيديو في برلين ، ألمانيا. في هذه الحلقة ، يشارك السيد الغيلي ما ألهمه لمتابعة رحلته المهنية في مجال الاتصال العلمي.

يشاركنا أيضاً التحديات التي يواجهها في ظل إنتشار المعلومات العلمية الخاطئة واين يرى توجه مجال الاتصال العلمي في المستقبل

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Nicole Chu from the University of Ottawa speaks with Chloe Yap, MD-PhD Candidate at the Mater Research Institute and the Institute for Molecular Bioscience, University of Queensland and Fulbright Future Scholar currently visiting UCLA. In this interview, Chloe shares the major findings from her recent work published in CellPress Journal titled “Autism-related dietary preferences mediate autism-microbiome associations”. Tune in to learn more about Chloe's research on the brain-gut-microbiome axis and its relationship to our social mind. 

Learn more about this study:  https://t.co/ZJpQ2Tkr44 

Timestamps:

1:30 - Major findings from the paper?
3:28 - What is the gut microbiome and its role in our health?
6:30 - Hypothesis "hype" around the gut microbiome driving autism?
8:57 - "Big data" analysis method
12:17 - Future takeaways to help improve the standard of care for autism? 

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Nicole Chu from the University of Ottawa speaks with Dr. Richard Lee, Professor of Stem Cell and Regenerative Biology at Harvard University and Professor of Medicine at Harvard Medical School. Dr. Lee is also a Senior Physician at the Brigham and Women's Hospital and Leader of the Cardiovascular Diseases Program at the Harvard Stem Cell Institute. Tune in to this episode and learn more about Dr. Lee's research on induced pluripotent stem cell (iPSC) derived cardiomyocytes for heart regeneration. 

Learn more: https://hscrb.harvard.edu/labs/lee-lab/

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Our host and producer Ana Spasojevic from the University of Ottawa speaks with Dr. Milica Radisic, a Professor at the University of Toronto’s Institute of Biomaterials and Biomedical Engineering. Dr. Radisic’s research aims to enable cardiovascular regeneration through tissue engineering and the development of novel biomaterials. In this Curiosity Capsule, Dr. Radisic discusses her pioneering work in the engineering of cardiac patches, generating beating in-vitro heart tissues from stem cells via electrical stimulation.

Learn more about Dr. Radisic’s research: https://www.labs.chem-eng.utoronto.ca/radisic/

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Tuba B. from the University of Ottawa talks to Dr. Joanne Lemieux a Professor of Structural Biology at the University of Alberta in the Faculty of Medicine & Dentistry. Most recently, during the COVID-19 pandemic, as the principal investigator on the study, Dr. Lemieux worked to develop an antiviral drug against coronavirus disease. In this interview, Dr. Lemieux speaks on her discovery of antiviral protease agents that interfere with SARS-CoV-2, the chemical design process of drug development, and her perspective on the future of antiviral pills. 

Learn more: https://lemieuxlab.biochem.ualberta.ca/ 

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Tune into our latest episode featuring Dr. Nicole Racine, clinical psychologist and post-doctoral research fellow at the University of Calgary and the Alberta Children’s Hospital Research Institute. In this episode, Dr. Racine shares actionable insights on the global-wide mental health crisis youth and adolescents are facing during the pandemic. Dr. Racine discusses topics such as the reopening of schools across Canada, possible long-term impacts the pandemic could have on Youth mental health, and much more.

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Neste episódio, o Dr. Pedro Curi Hallal fala sobre os desafios da Atividade Física em diferentes países e na era do COVID-19, como aumentar a participação nisto e tornar-se mais ativo, e o que está sendo feito na área de exercício físico para superar a sub-representação das mulheres na ciência.

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In this episode, Dr. Pedro Curi Hallal talks about the challenges of physical activity in different countries and in the era of COVID-19. Dr. Hallal also shares with us his view on how to become more physically active and what is being done in the exercise field to overcome the under-representation of women.

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Tune into our latest episode featuring Megan Reich, a Ph.D. Candidate in Biology at the University of Ottawa. Megan traveled 20,000 km to collect milkweed and create an isoscape of the Monarch butterfly’s annual migration journey. In this episode, Megan explains the specific role Strontium isotopes play in the ecological conservation efforts of Monarch butterflies. 

Learn more: https://www.saivelab.com/

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Nicole Chu from the University of Ottawa interviews Dr. Emily Chung, a digital journalist at CBC News who covers topics in Science, the Environment, and occasionally biotechnology. Before pursuing a career in science writing, Emily received a Ph.D. in Chemistry from the University of British Columbia. Emily shares with us how the COVID-19 pandemic has impacted health and science news coverage at CBC and addresses the importance of accurate scientific communication.

Learn more: https://www.cbc.ca/news/science 

0:27-Intro 

1:35-What is the process behind publishing science news stories?

5:42-Challenges of covering COVID-19 as a news topic?

7:00 - Has COVID-19 impacted science coverage at CBC?

8:28 - Your favourite article you have written so far?

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Tune in to our latest episode featuring Madhura Rao, a PhD Candidate from Maastricht University in the Netherlands researching food sustainability and safety. Madhura speaks on the concept of food waste valorization and shares suggestions on how our food systems can be made more sustainable by businesses and the government.

Learn more: https://madhurarao.com/

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BioRender: Revolutionizing Visual Science Communication. Tune into our latest episode featuring Shiz Aoki, co-founder, and CEO of BioRender and previous Lead Medical Illustrator at National Geographic. BioRender is a Canadian start-up with the goal of empowering scientists to curate their own medical illustrations quickly and consistently. In this episode, Shiz shares with us the story behind the formation of BioRender and some pieces of advice for aspiring medical illustrators.

Learn more: https://biorender.com/

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渥太华大学褚慕佳采访姚澤民教授。姚教授已从渥太华大学退休。 2002年至2013年,姚教授被任命为渥太华大学BMI系主任及创始人之一。BMI是生物化学、微生物学和免疫学的简称。姚教授分享了他30年在学术研究方面的经历并且他如何永远保持对科学的好奇心了解更多关于姚澤民教授,请浏览:https://med.uottawa.ca/bmi/en/people/yao-zemin

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Tune into our newest episode featuring Dr. Zemin Yao, a Professor (emeritus) and the former Chairman (2002 through 2013) of the Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine at the University of Ottawa. Dr. Yao speaks on his career and how he has maintained his love for research after a career of 30+ years of research in academia.

To learn more, please visit: https://med.uottawa.ca/bmi/en/people/yao-zemin

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Sol Vidal from the University of Ottawa Heart Institute talks to Leonard Benoit from the Toronto Central Regional Cancer Program. Join us in this Beats Research Radio episode as we speak with Leonard Benoit, the Indigenous Patient Navigator for the Toronto Central Regional Cancer Program, about the importance of his role to make our healthcare system more culturally safe and accessible for indigenous people in Canada.

Learn more: www.Trcp.ca

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Nicole Chu from the University of Ottawa talks to Dr. Carole Yauk, a Professor in the Department of Biology, University of Ottawa, Adjunct Professor in the Department of Biology, Carleton University, and President of the Environmental Mutagenesis and Genomics Society. In this episode, Dr. Yauk speaks on the importance of toxicogenomics in public health and how her lab, the GReAT Lab, is modernizing chemical risk assessment methods using genomic approaches.

Learn more about Dr. Yauk's research: https://caroleyauk.weebly.com/

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Isabela R Marçal chats with Dr. Leila Mostaço-Guidolin about her research on image analysis, extracellular matrix remodeling, and how those are helping her to understand issue function during normal and disease processes as well as in response to treatments. 

Learn more about Dr. Leila Mostaço-Guidolin's research: https://carleton.ca/mostacoguidolin/

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Isabela R Marçal chats with Dr. Leila Mostaço-Guidolin about her research on image analysis, extracellular matrix remodeling, and how those are helping her to understand issue function during normal and disease processes as well as in response to treatments. 

Learn more about Dr. Leila Mostaço-Guidolin's research: https://carleton.ca/mostacoguidolin/

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Janis Petït talks to Dr. Gad Sabbatier, Projet Manager at Axelys, and Manager and Founder of Mentorship and Professional Development Program for the Canadian Biomaterial Society. In this interview, Dr. Gad Sabbatier shares his experience in mentorship and explains us why do need to more for mentoring the future generations of Scientists and Engineers in Canada. 

Learn more about Dr. Gad Sabbatier’ work in mentorship at the Canadian Biomaterials Society here: https://biomaterials.ca/

Learn more about Dr. Gad Sabbatier here: https://ca.linkedin.com/in/gadsabbatier

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Nicole Chu from the University of Ottawa talks to Dr. Anna Blakney, Assistant Professor in the Michael Smith Laboratories and School of Biomedical Engineering at UBC, member of #TeamHalo, and TikTok Science Educator with over 3 million likes and 200,000 followers. In this conversation, Dr. Blakney shares her research experience on COVID-19 mRNA vaccines and her use of the social media platform, TikTok, to communicate science accurately and debunk vaccine misinformation.

Learn more about Dr. Blakney’s research here: https://blakneylab.msl.ubc.ca/

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Hallie Arnott from Zimmer Biomet speaks with Dr. Todd Hoare, a professor with the Department of Chemical Engineering at McMaster University. Dr. Hoare explains how his team designs “smart” hydrogel-based materials for multiple applications, including the biomedical industry and agriculture. Dr. Hoare provides some tips and tricks on how to effectively design a hydrogel for translation into the industry. Dr. Hoare’s work has been profiled by Popular Science, Maclean’s, and BBC for its potential in solving clinical challenges through innovative smart materials design.

Learn more www.hoarelab.com and https://control-create.mcmaster.ca/

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Nicole Chu from the University of Ottawa talks to Dr. Heather Sheardown, Tier 1 Canada Research Chair in Ophthalmic Biomaterials and a Professor of Chemical Engineering at McMaster University. Her research focuses on developing new polymeric materials and drug delivery systems for all areas of the eye to combat ocular disease and blindness. In this interview, Dr. Sheardown speaks on the challenges when commercializing academic technologies, her experience developing academic-industry collaborations with major companies like Ripple Therapeutics and EyeGate, as well as the C20/20 initiative she is leading, established with the 20/20 NSERC Ophthalmic Materials Network.

To learn more, please visit: https://www.sheardownlab.ca/

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Janis Petït talks to Dr. Alex Mihailidis, the Scientific Director of the Intelligent Assistive Technology and System Lab (IATSL) and Associate Vice President - International Partnerships at the University of Toronto. In this interview, Dr. Mihailidis shares his ongoing research on artificial intelligence and robotics for health and wellness and some pearls of wisdom for young researchers. 

Learn more about Dr. Alex Mihailidis’ work here: https://www.iatsl.org/

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Hallie Arnott from Zimmer Biomet talks to Chris Gunn, the lead photographer of the James Webb Telescope project at the NASA Space Goddard Flight Center since 2009. Chris won NASA Photographer of the Year 2019 and has had his photography work published in National Geographic, Wired Magazine, Popular Science, and The New York Times. In this interview, Chris shares with us some of his favorite moments photographing the Webb telescope, the importance of science communication at NASA through photography, and much more! 

Learn more about Chris’ photography work here: https://www.chrisgunn.com/