In conversation with...: Recent Episodes

eBioMedicine

Our Editors and the journal’s authors explore their research and its impact on people’s health, health care, and health policy in this regular podcast.

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Dr. Wenqing Li joins Peng Zhang to discuss a recent study integrating genetics and transcriptomics for risk stratification of gastric cancer.

The conversation explores the global epidemiology of gastric cancer, its high prevalence and mortality rates, particularly in East Asia and China, and the complex interplay of genetic and environmental risk factors, notably Helicobacter pylori infection.

Read the full article:

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(25)00211-7/fulltext?dgcid=buzzsprout_icw_podcast_July_25_ebiom

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Prof Alisa Clyne and Dr Callie Weber from the University of Maryland speak to Dr Gita Thapaliya about an eBioMedicine article examining the impacts of APOE-ε4 and exercise training on brain function and metabolism.

Read the full article:

https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00523-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Dr. Boyi Yang joins Peng Zhang to discuss the credibility of the relationship between green space and human health.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00297-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Dr. Lei Chen from The First Affiliated Hospital of Sun Yat-sen University discusses her publication "Approaches to scarless burn wound healing: application of 3D printed skin substitutes with dual properties of anti-infection and balancing wound hydration levels".

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00297-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Prof Torben Hansen from the Novo Nordisk Foundation Centre for Basic Metabolic Research, the University of Copenhagen, speaks to Gita Thapaliya about an eBioMedicine article examining the interplay between birth weight and obesity in determining childhood and adolescent cardiometabolic risks.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00240-8/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Dr. Mo Li from Peking University Third Hospital discusses his publication "PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response".

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00164-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Sanja Jelic & Daniel Gottlieb join eBioMedicine to discuss the use of continuous positive airway pressure in obstructive sleep apnoea and its impact on cardiovascular and inflammatory markers.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00050-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Sanja Jelic & Daniel Gottlieb join eBioMedicine to discuss the use of continuous positive airway pressure in obstructive sleep apnoea and its impact on cardiovascular and inflammatory markers.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(24)00050-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Drs. Pasquier and LeGrand join eBioMedicine to discuss their stepwise approach to unveil druggable cancer vulnerabilities and to fast-track the identification of synergistic combinations against glioblastoma.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00317-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Alan Dangour joins eBioMedicine to discuss climate change and health, our recently published Series, and projects they are working on at The Wellcome Trust.

Read the full Series:
https://www.thelancet.com/series/climate-change-and-health?dgcid=buzzsprout_icw_podcast_generic_ebiom

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John Cryan joins eBioMedicine to discuss how the microbiome-gut-brain axis regulates social cognition and craving in young binge drinkers.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00007-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_ebiom

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Drs Berbís and McClintock join eBioMedicine to discuss the survey they conducted with experts, forecasting the role of AI in pathology within the next decade.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00609-0/fulltext?dgcid=buzzsprout_icw_podcast_ebiom_lancet

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Drs Robinson and Reese join eBioMedicine to discuss their findings on semantic phenotypic clustering long COVID subtypes observed in N3C and RECOVER programmes.

Read the full article:
Generalisable long COVID subtypes: findings from the NIH N3C and RECOVER programmes

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Drs Zeng join eBioMedicine to discuss their study of a novel molecular glue, called bufalin.

Read the full article:
Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy

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Drs Fischer & Horvatits join eBioMedicine to discuss their findings of microplastics in cirrhotic liver tissues. 

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Dr Carmel Harrington joins eBioMedicine to discuss about their findings of a potential biomarker for sudden infant death syndrome.

Read the full article:
Butyrylcholinesterase is a potential biomarker for Sudden Infant Death Syndrome

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Drs Matthieu Pernot, Clément Papadacci & Alexandre Dizeux join eBioMedicine to discuss about ultrasound localization microscopy, brain imaging and scientific communication.

Read the full article:
In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy

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Dr Lilian Hunt joins eBioMedicine to discuss a series of articles we commissioned on the topic of diversity in medical research.

Read the articles :
Individual differences and diversity in human physiological responses to light
Towards equitable and trustworthy genomics research
Ensuring that biomedical AI benefits diverse populations

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Dr Jun Seok Son and Dr Min Du join eBioMedicine to discuss maternal exercise and offspring’s health, especially diet-induced obesity and metabolic disorders.

Read the full article:
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

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Professor Marc Mansour and Dr Victor Llombart join eBioMedicine to discuss the “undruggable” MYC in cancer. 

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Rachel Deer joins eBioMedicine to present a study encouraging characterization of long COVID symptoms via human phenotype ontology.

Read the full article:
Characterizing Long COVID: Deep Phenotype of a Complex Condition

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James Zou & David Ouyang join eBioMedicine to discuss issues around deep learning and hidden clinical correlates.

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Prof Beate Kampmann, Dr Karen Keddy, and Prof Peter Ghazal discuss a new cross-journal Series in The Lancet Infectious Diseases and eBioMedicine addressing the potential for and challenge of applying big data to childhood infectious diseases in LMICs.

Read the full Series:
https://www.thelancet.com/series/big-data-childhood-infections-LMICs 

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Dr Anthony Chirwa and Dr Ben Morton join eBioMedicine to discuss controlled infections in Streptococcus Pneumoniae and the importance of localised research.

Read the full article:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00372-8/fulltext

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Jodi Sherman joins Julie Stacey and Liam Messin of eBioMedicine to discuss the intersection between healthcare and climate change.

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How can we ensure that research being conducted is relevant to its ultimate end-users? Grace Fox and Dr Manoj Lalu join eBioMedicine to discuss the importance of patient engagement in preclinical research.

Further reading:
Patient engagement in preclinical laboratory research: A scoping review

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Dr Aleix Prat on the relationship between chemotherapy effectiveness and menopause in patients with breast cancer.

Further reading:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00244-9/fulltext

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Dr. Viviana Simon and Dr. Maria Rescigno discuss their proposal that people who have recovered from symptomatic COVID-19 may require only one dose of an mRNA vaccine.

Further reading:
https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(21)00194-8/fulltext