Prevmed: Recent Episodes
Dr. Ford Brewer
At PrevMed, we focus on preventing not only heart attacks and strokes but also type 2 diabetes, cognitive decline, and other chronic diseases. We serve patients who already experienced an event, as well as those who have not developed an event or diagnosis. Our approach is to reduce or eliminate risks through attentive care and state-of-the-art genetic testing, imaging, lab tests, and telemedicine options.
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or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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https://www.prevmedcare.com/glucose-manager
Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
Get My 7- Step Heart Attack Prevention Protocol free ebook here: https://45413573.hs-sites.com/ebook
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
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Ready for your personalized care plan? Call us Now: 859-721-1414
or visit http://www.prevmedcare.com/sp1
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Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Looking to improve your health and add decades to your life?Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).All you need to do is click the link below to sign up. Sign up here: https://prevmedhealthtampa.com/Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Learn more here: https://prevmedhealth.com/
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
Have you registered for the PrevMed Health Dallas Summit yet? We have an early bird sale going on right now. Reserve your spot now while seats are available.
Hear from top medical professionals on how to avoid heart attacks, cardiovascular diseases, strokes, and age healthier. Don't miss this life-changing event!
Sign up now at https://www.prevmedhealthevents.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Looking to improve your health and add decades to your life?
Join me and the PrevMed team Dec 1st & 2nd in Tampa for the Heart Attack and Stroke prevention Conference.
You’ll not only learn how to prevent heart attack and stroke using my battle tested system, but also access accurate, predictive testing the majority of physicians NEVER USE (because they don’t know how).
All you need to do is click the link below to sign up.
Sign up here: https://prevmedhealthtampa.com/
Or if you’d like to see the PrevMed team virtually and reverse your chronic disease, Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time.
Learn more here: https://prevmedhealth.com/
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
Ready to reverse your chronic disease? Dr. Ford and the PrevMed staff are currently accepting new patients for a limited time. Book an appointment here: https://prevmedhealth.com/
To ensure quality of care there are limited openings available so act quickly.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·Newsletter Sign Up
·Purchase an Appointmen Today!
·PrevMed's Locals
·PrevMed's Rumble
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
·PrevMed's Instagram
·PrevMed's LinkedIn
·PrevMed's Twitter
·PrevMed's Pinterest
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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This is part 2 of a series on Diabetic Glucose Spikes Seen in "Healthy Adults". This video reviews PLOS Biology. Micheal Snyder, head of the genetics department at Stanford, and Heather Hall, a graduate student. They used Continuous Glucose Monitor (CGM). 15% of otherwise "healthy" adults had prediabetes. 2% met the criteria for full-blown diabetes. Age and BMI were major drivers of high variability patterns.
https://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.2005143 https://www.medscape.com/viewarticle/900134
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Episode NotesFor more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For over 25 years now, oral pathogens have been suggested as a root cause of cardiovascular disease. Since then, solid evidence was lacking to support this theory. More recently, 2016 Level A evidence has shown that oral pathogens do indeed cause CVD. Here is how to identify if you have those oral pathogens and how to get them treated.
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In JACC, Oct 2017, (Jl of the American College of Cardiology), there was a beginning of a series on colchicine and heart attack/stroke prevention. This focus on cardiovascular inflammation (CV) inflammation was started again in June of 2017. It was tripped off by the announcement of the CANTOS trial by Paul Ridker. I review the cellular view of plaque inflammation. Then I talk about colchicine. Colchicine was first recorded as a treatment for arthritis, rheumatism, which is caused by similar inflammation of the joints. I review the Clinical Trials.gov site on the COLCOT study, an upcoming trial using colchicine.
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Is there a benefit to self-monitoring blood glucose for Type 2 diabetics who don't use insulin? Will the ADA recommendations help us learn to better manage our insulin resistance and diabetes?
About John Lorscheider - John is a frequent contributor. He’s also a PrevMed patient. Like most of us, John’s family and personal history include significant cardiovascular risk.
John came from a technical background and spent his entire career in providing engineered fluid process systems and equipment to industry, as well as performing root cause failure analyses for his customers.
His own study and research made it clear he wasn’t getting the whole story about prevention from his docs. They just didn’t know. So he’s been in several roles of running prevention medical groups to help further the science.
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UCLA recently published a study indicating over half of Californians are prediabetic. Other sources indicate that 90% of us with prediabetes are totally unaware. Insulin resistance is the #1 cause of cardiovascular inflammation. CV inflammation is, in fact, the #1 cause of heart attack, stroke, and dementia - the biggest killers and disablers.
The Freestyle Libre by Abbott is now available. It provides continuous glucose monitoring. It also provides graphs, long duration of readouts, and analysis of ranges.
This is my first application of this breakthrough device. It's simple, easy, and painless.
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Reo52 suggested I do a video on sulforaphane. It was great advice! Sulforaphane is one of the isothiocyanates (like glucoraphanin). These are phytochemicals ( plant molecules) that contain sulfur. They have strong anti-cancer properties. There has actually been excellent research in NATURE and CANCER RESEARCH investigating the biochemical mechanisms. Although it's not completely understood, there are indicators re: gene amplification, anti-inflammatory mechanisms. It not only prevents cancers but is being used in treating them. There is even good research indicating that it may be one of the few possible treatments for autism spectrum disorder.
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Recent studies like CANTOS have raised the idea that colchicine could decrease plaque inflammation. Colchicine is an old, inexpensive anti-inflammatory medication.
Basically, there are several studies now looking at this. One study has shown a decrease in plaque volume by LAPV (Low Attenuation Plaque Volume) studies. It's been termed as "intriguing" by experts such as Paul Ridker, MD at Harvard, that has focused on cv inflammation for years. Ridker was the Principle Investigator of the CANTOS trial that was announced in June 2017. The CANTOS trial created excitement and surprise in the global cardiology community, despite the fact that this has been known for over a decade.
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Type 1 Diabetes isn't supposed to happen much after age 15. After age 30, it's considered rare - or nonexistent. That's just not true. This article shows that the incidence of Type 1 diabetes is just as common as ages 16-30 and almost as common as 0-15.
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Dr. Christopher Ramsden, dietary research at the NIH, is described by Scientific American, as "the Indiana Jones of Biology". In 2011, he noticed that a large and expensive study financed by the NIH was published late and with very little of the promised data. The principle investigator, Dr. Ivan Frantz, of the University of Minnesota, had died in 2009. But his son was a physician in Mayo. The son drove 90 minutes back to Dr. Frantz's home.
In the basement, there were file folders and boxes containing - IBM magnetic data tapes and even data punch cards. Dr. Ramsden was able to get the data off the tapes and card. He analyzed it and published it in BMJ in April 2017 (British Medical Journal).
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The Power of Calm, or Address Stress program contains a series of books and apps. It includes a 14-day introductory program, introductory books, and an app I accessed on my iPhone.
Advantages:
it includes books as well as an app for those that need one or the other media
it has good content describing and defining stress
lots of pictures are included
It even includes in written and pictures mention of telomere length and size of the hippocampus and prefrontal cortex
the app is easy to learn, intuitive
the app includes lots of focus on breathing and soothing sounds
it provides good lists of ways to manage stress, like yoga, tai chi, and mindfulness
What it's not good at:
it doesn't get deep in terms of scientific citations
neither the book nor the app gets that deep in terms of the concepts covered in Palouse, Tolle, or Untethered Soul, or westernized concepts of Buddhist concepts of mindfulness
it also does not even mention these important resources for understanding and managing stress.
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Heart attack and stroke have many causes and risk factors, ranging from lifestyle, obesity, diabetes, hypertension, high cholesterol, inflammation, dental infections, stress, etc. Which of these is the real cause? Maybe it's a common factor, like the mitochondria and cellular respiration. The reality is that we do not know. Cellular respiration and the mitochondria theory can be helpful in terms of both research questions and lifestyle, treatment issues. The functional item is what comes of the knowledge. What can we do to prevent or reverse early disease? For example, we know that there are many things we can do to decrease disease: a proper diet, exercise, and specific medications when indicated. There are a couple of examples: ACE inhibitors and insulin resistance. We know that ACE inhibitors and ARBs improve insulin resistance. ACE inhibitors improve inflammation as well, so we recommend those when the patient tolerates them. Beta-blockers have been shown to improve life expectancy post cardiovascular events. But one thing we often don't think about is the fact that so much cardiovascular risk is driven by insulin resistance ( est 70%). If that's the case, should we consider beta-blockers that have a positive impact on diabetes? I think so. But this is often ignored in the hurried medical practice. If you're on Toprol or metoprolol and have cardiovascular risk and diabetes, consider carvedilol or Coreg.
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Vit D was thought to be a non-issue when it was provided as a preventive of Rickets. Rickets was a disabling disease of bone deformity of children. Over the past decade, we've discovered that Rickets was just the tip of the iceberg. Now we're discovering multiple functions, especially anti-inflammatory in nature. Significant evidence supports the prevention of cardiovascular disease, multiple cancers, and even mental health issues. The Wikipedia site on Vit D appears outdated. It doesn't mention the recent data about these issues. Vit D toxicity is a debatable condition. Toxicity has been reported to kidneys at doses over 50 times the recommended amount. Vit D increases calcium absorption by the gut. But what happens next? That's supposed to be where Vit K2 enters the picture. Vit K2 is involved in getting calcium to the bone. There is evidence that k2 decreases the deposition of calcium in the artery walls. The scientific evidence in this area is growing.
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This is an unboxing video. It's Day 2 of my experience with Prolon. Prolon is a fasting-mimicking (meal replacement) product developed by one of the world's leading researchers in the genetics and biochemistry of longevity. He has demonstrated improvement in multiple markers, including cholesterol, inflammatory markers, stem cell performance, and the metabolic pathways IGF-1, mTOR, and PKA. These pathways are all related to aging. The actual contents, foods, soups, supplements, and teas are demonstrated. There is also a brief biochemistry explanation re: the tea sweetener - glycerine. Glycerine is a carbohydrate, but it is low glycemic. Perhaps more important, glycerine is the backbone of triGLYCERIDES - or fat molecules. So in a fasting state, you should be making ketones and creating/burning glycerine. In other words, the sweetener used is already being made by the body in the fasting state.
To get Valter Longo's Prolon ( Fasting Mimicking Diet, go to: https://prevmedheartrisk.gethealthy.s...
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You can obtain Valter Longo's Fasting Mimicking Diet (Prolon) at: https://prevmedheartrisk.gethealthy.s... There is a lot of buzz re: curing diabetes. Valter Longo at USC Davis is one of the world's top biochemists/geneticists focused on gerontology or longevity. He's demonstrated stem cell-mediated regrowth of beta cells in the pancreas in mice. The mice were cured of their diabetes. Can we do that with men as well? Other articles by Longo are reviewed demonstrating improvement of multiple metabolic indicators, mostly driven by the glucose metabolism pathways including mTOR, AMPK, ILG-1. A final academic article demonstrates the probable mechanism. Caloric restriction or fasting clearly increases the transcription of genes that code for these proteins. P53 and FOXO appear to be acting agents in this transcription improvement - or upregulation. In the end, this all makes sense. Episodes of caloric restriction cause our bodies to transcribe more of the genes involved in energy metabolism. It makes sense after.
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There is NO DEBATE about the fact that getting less than 7.5 hours of sleep causes obesity, diabetes, high blood pressure, dementia, and early death. We'll do a brief mention of science reviews of the literature. Here are some links to studies: https://www.hindawi.com/journals/ije/... http://journals.plos.org/plosmedicine... http://journals.plos.org/plosmedicine... Science has been there for a long time. Unlike the debate on low fat and plant-based vs low carb, there is absolutely no debate about the science in this area. Sleeping less than 7.5 hours causes diabetes, insulin resistance, obesity, hypertension, and death. About Dr. Brewer - is a physician that started as an Emergency Doctor. After seeing too many patients coming in dead from early heart attacks, he went to Johns Hopkins to learn Preventive Medicine. He went on the run the post-graduate training program (residency) in Preventive Medicine at Hopkins. From there, he made a career of practicing and managing preventive medicine and primary care clinics. His later role in this area was Chief Medical Officer for Premise, which has over 500 primary care/ prevention clinics. He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, stroke, and diabetes prevention clinic. At PrevMed, we focus on heart attack and stroke and Type 2 diabetes prevention by reducing or eliminating risk through attentive care and state-of-the-art genetic testing, imaging, labs, and telemedicine options. We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event. Our team of senior clinicians includes internationally recognized leaders in the research and treatment of cardiovascular disease, preventive medicine, and wellness. We also provide preventive medicine by telemedicine technology to over 30 states.
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Homocysteine, folate, methylation, and monoamine metabolism in depression. Teodoro Bottiglieri et al. British Medical Jl This is an old study. It's been cited over 500 times. Here's why. they took severely ( hospitalized) depression patients and controls: and 1. it looked at methylation indicators in serum, red blood cells, and even cerebrospinal fluid; 2. documented an inverse relationship between serum homocysteine and all other indicators for products of methylation, INCLUDING metabolite indicators of monoamine neurotransmitter metabolism. In other words, there was strong evidence that the methylation metabolism failure was linked to depression.
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Diet 101 is a companion book to Blood Sugar 101, but Jenny Ruhl. She's the founder of the award-winning website Blood Sugar 101. Like Blood Sugar 101, this is a very well-researched book. And it also was written for diabetics. However, the information provided is important for all of us. And it's not just for diets and weight loss. It's also for the Type 2 diabetes pandemic. She does an excellent review of the new studies coming out over the past few years re: studies of diets using stronger scientific techniques. Actually, diets routinely don't do well. Here's why; people don't stick with them. 6-month follow-up for almost all diet studies has been abysmal. Low carb diets have shown marginal improvement. Do ketogenic diets have a metabolic advantage? Yes, but you can't eat 7000 calories per day. Jenny's a proponent of low-carb diets, especially for diabetics and prediabetics. But she fairly reports problems and shortcomings, like grumpy moods, quick loss of improvement when carbs are re-introduced, failure to prevent or cure diabetes or prediabetes.
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This is part 2 with a summary of the scientific literature on CoQ10 and Ubiquinol. It's clear that CoQ10 is safe, important, expensive, that it's a key component of animal cell respiration and drives over 90% of our energy production, it's depleted during disease states such as heart failure, stroke, and cardiovascular inflammation. It is also depleted by statins. But what's not clear is whether improving levels of CoQ10 actually improve athletic performance and disease outcomes.
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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We're testing the home Insulin Survey by Imaware. I unbox & do my first sticks. And guess what my glucose challenge will be - a 20 oz Cherry Coke.
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Diabetes can lead to eye problems, which include diabetic retinopathy (DR). This happens when high blood pressure causes retinal blood vessels to leak fluid or bleed. DR and other diabetes complications are also associated with hyperhomocysteinemia (high homocysteine levels). Thus, there should be very little homocysteine left in the bloodstream. Hyperhomocysteinemia leads to arterial damage and blood clots. It is usually seen in carriers of MTHFR gene mutations. If you have high levels of homocysteine in your blood, it may be a sign of a vitamin deficiency, heart disease, or a rare inherited disorder. Let's discuss MTHFR gene mutation & high homocysteine levels, their association with diabetic retinopathy & other diabetes complications, and the role of methylated B vitamins & supplements in this area.
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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A new study, published in Stem Cell Reports, looked at transforming stem cells into beta cells that are more responsive to blood glucose levels to produce insulin. While stem cells may sound exciting (especially for type 1 diabetics), I doubt it will be a long-term reliable cure. We still have to target the main problem—insulin resistance.
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Dr. David Fajgenbaum and his team devoted most of their resources to the fight against the COVID-19 pandemic. They reviewed 150+ old and existing drugs currently used for coronavirus treatment. Some that stood out are antiviral drugs and those used to address cytokine storms.
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Doctors also get sick. Our guest, Dr. Kevin McChord, a specialist in family medicine, shares his bout with heart attack, fatty liver, DVT, & insulin resistance. We'll talk about NAFLD (non-alcoholic fatty liver disease), insulin resistance, and other health topics.
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For decades, cardiac stress tests have been a go-to test for detecting heart disease. However, in the past couple of months, stress tests, as well as other elective tests & procedures, were deferred as attention was put into controlling the coronavirus. Does this mean stress tests aren't really necessary?
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We primarily think heart attack to be a man's disease. But in reality, it's the common cause of disease in both men and women in the US. Women's symptoms typically differ from those of men, usually leading to late diagnosis. In this video, let's discuss heart disease in women, symptoms, risk factors, and prevention.
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In this video, let's discuss the difference between type 1 diabetes and type 2 diabetes, and the various ways of testing diabetes (including the oral glucose tolerance test and hemoglobin A1c).
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The brain is found to be one of the targets of the coronavirus, with some severe cases characterized by confusion, delirium, or an altered mental state.
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Joining me in this live session is infectious disease expert Dr. David Vigerust. We'll discuss genes that may explain why some people get severely sick with COVID-19, coronavirus testing, vaccines, and other topics about COVID-19.
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It isn't the same as convalescent plasma therapy, but the experimental antibody cocktail therapy is being eyed as COVID-19 treatment. Apart from vaccines, it's worked on as another way to provide coronavirus immunity. In this video, let's discuss antibody cocktails, their potentials, and their challenges.
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Anaphylaxis is a treatable condition with no permanent effects. Nevertheless, news of allergic reactions has raised fear about the risks of the new COVID-19 vaccines. Polyethylene glycol (PEG) is used as an excipient in Pfizer & Moderna vaccines and has been implicated as a rare, “hidden danger” cause of anaphylaxis.
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Widespread coronavirus testing is key to identify infected people, trace & isolate their contacts, and prevent more waves of COVID-19 infection. The benchmark of how many tests we should do is that positives should be 10% or lower out of the total done. Currently, in the US, around half of the states fail to meet the benchmark.
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Researchers found that type 2 diabetics who followed a low-carb diet for at least 6 months experienced greater rates of remission than those who did not.
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With Apple and Google at the helm of making contact tracing app, the US is preparing to contain the COVID-19 pandemic with contact tracing. But as seen in some countries, there are issues with the practice, particularly with privacy and the extent of coronavirus tests done.
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Are supplements safe? In this live session, we'll talk about the safety of supplements. I'll also tackle metformin and NDMA, folate and folinic acid, and further questions from viewers about vitamin K2, vitamin D3, fish oil, and omega 3, among other things.
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This is my weekly YT Live event. Tonight we talked about the new & first randomized clinical trial on Vit D and T2DM prevention. We also talked about limiting statin use to those with plaque, and finally, we talked about the glycocalyx. It's where it's all happening.
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CDC advised people aged 60 years and up and those with diabetes and other health issues to stock up on supply and practice social distancing.
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We'll cover a recent article from the New England Journal of Medicine titled "Effects of Intermittent Fasting On Health, Aging & Disease." Here, we'll discuss intermittent fasting, its benefits, how it differs from time-restricted eating and caloric restriction. I also took questions from viewers about homocysteine, methylation, diabetic eye disease, methylated vitamins (including methyl folate), vitamin K2, among other things.
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As more people are getting a carotid IMT (CIMT) scan, they're also curious about how to interpret their reports. Unfortunately, not a lot of doctors are familiar with the CIMT test. In this video, I'll discuss CIMT interpretation, arterial age, mean max, intima-media thickness, and how CIMT differs from other carotid ultrasound techniques. I also answered questions about vitamin K2, insulin resistance, niacin, statins, metformin, methylation, and gene testing.
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People are avoiding going to hospitals and clinics during this COVID-19 pandemic. Instead, they're doing medical consultations through video calls or other online means. While many things are possible with the 4G and Wi-Fi, expect everything to get supercharged once 5G is widely available.
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On Dec. 29, 2020, the USDA & HHS released the 2020-2025 Dietary Guidelines for Americans (DGA). It contains new recommendations for pregnant & breastfeeding women, infants, & toddlers. However, it excluded updated scientific recommendations for daily sugar and alcohol intake.
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Are you visiting your dentist's office? Know what dentists can do (and should do) to protect their clients and themselves from COVID-19.
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I'm with Doug Thompson of the Wellness Dentistry Network. Today, we'll talk about telemedicine, teledentistry, and the connection between gum disease and prediabetes. Plus, some updates on COVID-19.
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I'm doing Prolon again after a 2-year gap. For the past 6 months, I've been doing a weekly 2-day water fast. Why would I try the FMD (Fasting Mimicking Diet) after getting a regular pattern of weekly water fasts? First of all, I noticed the 40-48 hours of water fasts are now passing by pretty quickly. It seems I'm adapting to it. I'm wondering if that has a biochemical adaption as well. I'm thinking it may be better to mix it up.
But there's the biggest thing: over 3/4 of my patients have a problem with weight. This is a great way to manage your weight. Sure, other things work - like water fasts. But I've seen VERY few people do water fasts. Low carb and Intermittent Fasting/ Time Restricted Eating also work very well for a long-term lifestyle change. But again, there are many methods for getting control of your weight - and CV inflammation - and Insulin Resistance. And these things are killing and disabling so many of us - any valid option should be seriously considered.
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Patient - Directed Care is happening! & it's one of the biggest components of the future of medicine. The goal of this channel is to stop heart attacks, strokes, dementia, blindness, erectile dysfunction, and a lot of other bad things. The scientific medical community is learning things every day that help us prevent these problems. One of our Forum subs, Fatmax, shares his recent experiences. Knowing what he now knows, he prepped for his first meeting with a new endocrinologist. She was impressed with his detailed knowledge and prep. She ordered everything he requested. It was a very pleasant experience for both of them.
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In this episode, I'll first talk about Alzheimer's disease, insulin resistance of the brain, and T3DM (type 3 diabetes mellitus). I also touched topics/questions from viewers about Gymnema Sylvestre ("the sugar destroyer"), statins, CV inflammation, FH, magnesium, HIIT, and sitting as the "new smoking."
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Debilitating symptoms can last long even after a person’s body has gotten rid of the coronavirus. Many COVID-19 survivors find themselves unable to shake sickness, fatigue, and other illnesses, weeks after they're cleared of the virus.
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This video describes the typical process for managing chest pain. Too bad it doesn’t work.
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I talked here about cardiovascular (CV) inflammation, the different laboratory tests for inflammation, as well as insulin resistance, and diabetes.
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More than 90 coronavirus vaccines are under development across the world. Researchers are trying various technologies, some of which still aren't used in a previously licensed vaccine.
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Random clinical trial (RCT) is the fastest route to learning whether experimental products work. In special cases, the US FDA issues EUA (Emergency Use Authorization) to allow the use of experimental products or approved products for unproven indications. Let's discuss RCTs and EUA, and some of the current COVID-19 treatments, like chloroquine, hydroxychloroquine, antivirals (like remdesivir), convalescent plasma therapy, vitamin C, and COVID-19 vaccine.
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The body naturally produces a protein called “interferon beta” as a response to viruses. Synairgen developed an inhaled interferon beta that targets lung cells, as opposed to an injected form that could produce more intense side effects.
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On July 14, 2020, NEJM published the results of Phase 1, dose-escalation, open-label trial of the ModeRNA vaccine. Its technology-enabled ModeRNA to speed up the process, bypassing and shaving the typical steps involved in vaccine development.
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In this video, we talk about herd immunity. Will it be a useful measure against the coronavirus spread? What portion of the herd should be immune to halt COVID-19 transmission? We also cover COVID-19 antibody and vaccination, social/physical distancing, 2 coronavirus transmission viral videos, and COVID-19 treatments and supplements.
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We're going to talk about whether we have reached the COVID-19 peak in the US and compare the US's standing with other countries. Plus, whether states are ready to restart the economy, and if yes, what measures should be done or maintained (like social distancing, continuous PPE use, coronavirus test and tracking, and use of thermal imaging camera).
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Accurate death certificates are necessary to determine where to focus resources to curb the coronavirus spread. However, the US has been struggling to track the coronavirus death toll accurately. In this video, let's tackle the reasons why this is the case.
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The number of T lymphocytes could drop significantly in COVID-19 patients. Researchers found that SARS-CoV-2 preys and kills powerful T cells that are supposed to kill the coronavirus, just like HIV.
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Based on two studies, it's surprising that pregnant women have very few or no COVID-19 symptoms at all. This is an unexpected reaction among a demographic that’s often more susceptible to becoming seriously ill from influenza and other infections.
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A new study conducted by Hong Kong researchers gives weight to wearing a face mask as a means to reduce COVID-19 transmission drastically. Subjects were hamsters, and face masks were used as cage barriers to protect healthy hamsters from the airborne transmission of the coronavirus.
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Academic labs in the US have joined the fight against COVID-19 by helping with coronavirus test efforts. However, nothing comes easy for them as they face several barriers.
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The demand for surveillance technology surged during the COVID-19 pandemic. But as companies started doing surveillance with technologies like thermal cameras, facial recognition, drones, contact tracing apps, and mobile location tracking, many raised concerns about privacy.
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If you then have a positive stress test, you’ll likely be led to the catheter lab for a coronary angiogram. If plaque is detected, you’ll then be recommended to have a coronary stent. This progression—from stress test to cardiac catheterization to stent—is tragically a common (yet often unnecessary) triad of cardiology procedures.
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Type 2 diabetes (T2D) is a metabolic disorder characterized by insulin resistance and insufficient insulin release from pancreatic islet β (beta) cells. But is T2D a result of a loss of β cells or a decline in β cell function? In this live session, let's discuss a study published in Cell Reports.
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Should you supplement your diet with fiber? In this video, we'll talk about fiber (psyllium) and cover some studies on whether fiber can decrease heart attack and stroke risk, blood sugar levels, and LDL cholesterol.
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Is it safe to eat takeout food during the COVID-19 outbreak? Food experts say yes, as there's no evidence of the coronavirus spread through food. Still, everybody (customer, seller, and delivery people) should practice physical distancing and surface sanitation when receiving and handling takeouts.
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Falls are the #1 cause of trauma death in the elderly. But according to the STRIDE trial which was published in NEJM, the # of injuries from falls has not declined despite intervention.
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Scientists say a much-feared “second wave” of infection may not wait until fall and instead may become a storm of wavelets breaking unpredictably across the US. This is as several states are coming out of lockdown.
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The coronavirus is so unpredictable that it brings a myriad of various COVID-19 symptoms. It often attacks the lungs, but it can also strike anywhere from the brain to the toes. Scientists believe this is due to the virus's capability to cause blood clots and trigger excessive inflammation ("cytokine storm").
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Most of our understanding of coronavirus immunity is based on studies on seasonal coronaviruses. However, we know that antibodies detected in SARS and MERS survivors linger for years. All these form the assumptions on what would be the expected immune response against COVID-19. Still, there are lots of questions, like COVID-19 reinfection, false-positive coronavirus test results, and the uncertainty of getting herd immunity.
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Due to the immunomodulatory properties of statins, it's assumed that they would help deal with cytokine storms in COVID-19 cases. While certain statins do work against inflammation, there's not yet enough evidence that they do work against COVID-19.
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Recent stroke patients with COVID-19 are in their 30s to 40s. This may be a direct consequence of blood problems that produce “mysterious” blood clots all over some people’s bodies. This blood-clotting appears to be a new and emerging COVID-19 complication.
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Intermittent fasting is said to have lots of benefits for many health conditions. It triggers a metabolic switch from glucose-based to ketone-based energy. It increases stress resistance and longevity. It brings physical and cognitive effects. It decreases the incidence of a range of diseases. However, despite these benefits, intermittent fasting also has its challenges. There is even a study saying it doesn't bring any difference.
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Let's talk further about COVID-19 modeling. This time, I'll show you how to predict the estimated peak time of COVID-19 outbreak and the ICU need/capacity in each US state.
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·PrevMed's website
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There's emerging evidence that vitamin D may be relevant against COVID-19 infection and its severe complications. Getting exposed to sunlight is the typical recommendation to increase vitamin D levels, though we recommend supplementing, then test and adjust the intake.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Let's talk about a paper titled "Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease." It was recently published in the New England Journal of Medicine last September 2019. In a nutshell, the study compares the long-term outcomes of patients who went through percutaneous coronary intervention (PCI) and stenting vs. those who went through coronary artery bypass grafting (CABG). Also, we covered questions that currently interest the live viewers, like Hashimoto's disease, the dawn effect, continuous glucose monitoring, methylome, HIIT, and carb diets.
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We'll cover an update on the use of ACE inhibitors and ARB drugs amid COVID-19, particularly on the "double-edged sword" nature of the two BP medications. Here's the link to the JAHA article: https://www.ahajournals.org/doi/10.11.... We'll also cover our telemedicine program for non-emergency care, other COVID-19 updates, vitamins C and D3, DIC (disseminated intravascular coagulation), prediabetes, and calcium score.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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The scientists at Los Alamos National Laboratory identified a new coronavirus strain, more widespread and more contagious than earlier versions (including the Wuhan coronavirus). They focused on a mutation called D614G, affecting the spikes of the mutant coronavirus.
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Amid the COVID-19 outbreak, there seems to be a marked decline in heart attack and stroke cases. Is it because these diseases have been classified as COVID-19 comorbidities? Probably not as there is also a decline in other conditions like appendicitis and acute gall bladder disease.
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To curb COVID-19 spread, the World Health Organization (WHO) sets 6 conditions for countries wanting to lift restrictions or end a coronavirus lockdown.
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In this video, we'll focus our talk on how COVID-19 is transmitted.
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·PrevMed's website
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The CDC has recently recommended the wearing of a face mask. I'm here with Janice, and we'll talk about face masks—N95 mask, fabric face mask, and how to make a simple DIY mask (one from Kente cloth and one from a T-shirt as seen on CDC's site).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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In this video, we discussed "social" vs. "physical" isolation in the midst of COVID-19. Plus updates on ACE Inhibitors, zinc supplements and ionophores, chloroquine and hydroxychloroquine, reinfection, coronavirus testing, and in-home medical care.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Let's talk about how China managed its COVID-19 situation. We'll also cover vaccine development efforts, herd immunity, and social isolation.
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·PrevMed's website
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In this live session, we discussed the current CDC policies regarding COVID-19 testing (very little of it) and "social isolation" vs. what's worked in other countries (greatly expanded testing, case finding, and quarantine). Plus, updates on ACE Inhibitors, zinc supplements and ionophores, chloroquine and hydroxychloroquine, HIV antivirals and coronavirus, reinfection, coronavirus test, and in-home medical care (telemedicine).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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In a study published in JAMA Cardiology last March 27, 2020, 27.8% of 187 COVID-19 patients in Wuhan, China, found to have a myocardial injury. Is the damage directly caused by the virus or caused by the inflammation? Knowing which really causes the heart damage would help docs understand what treatment to use.
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·PrevMed's website
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There are two types of coronavirus test—polymerase chain reaction test and the antibody test for COVID-19. Let's differentiate the two, and we'll also cover the CDC's guideline on coronavirus testing.
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·PrevMed's website
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During this COVID-19 pandemic, physical distancing will prove to be a crucial measure in saving a huge number of lives. This is supported by estimates from COVID-19 modeling tools, like the Imperial College, the Spanish flu, and the NIH models. Here's the link to Imperial College.
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Colchicine—an anti-inflammatory gout medication—appears to have a positive effect against CV inflammation. This is based on a recent article published in NEJM.
Not all anti-inflammatory drugs, though, have that similar effect, as seen in the case of Vioxx and methotrexate.
In this live session, I'll cover the colchicine study, the connection between inflammation and CV risk, the natural ways to decrease inflammation, as well as viewers' questions about metformin, statin, methylation HIIT, TG, and LDL.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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We made a lot of mistakes. We didn't prepare enough for this COVID-19 pandemic. We lack test kits and PPE. We fell short in vaccine research and social isolation plans. Not to mention the added risk brought by prediabetes, diabetes, and other underlying health conditions. But it isn't the end; we can ride this crisis.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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If you have a high TG level, there are ways to lower it—a healthy diet, lose weight, address medical conditions like prediabetes/diabetes. Sometimes, the doctor may prescribe meds, like Vascepa (icosapent ethyl). But is taking Vascepa worth it?
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Asking whether saturated fat is bad for CV health is looking for a simplified answer to a complicated issue. There are a lot of studies showing the two sides of this issue. In this video, I'll cover some of those studies, plus the acclaimed book "The Big Fat Surprise" by Nina Teicholz, and a new JACC article published in June 2020.
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Prolon Day 5 - Last day! Since the nap at noon on day 3, I have felt great! no fatigue or hunger. This is my Prolon Experience on a YouTube Live video discussion format.
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Restart the economy or remain on lockdown? Such a decision is not that simple for COVID-19-stricken locations. A NEJM article titled "From a Sprint to a Marathon in Hong Kong" detailed the steps Hong Kong has done on managing the COVID-19 pandemic.
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Kroger, Costco, and Walmart are recently limiting the number of entering customers and imposing physical distancing rules. We are going to cover that and other aspects of safe grocery shopping. We'll also talk about "victory gardens," telemedicine, and some COVID-19 updates.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Should we take a nitric oxide supplement? What connects nitric oxide with mouthwash rinse or dentistry in general? Does nitric oxide affect erectile dysfunction, heart attack, or stroke? In this live session, I'm with Dr. Doug Thompson, and we discussed nitric oxide benefits and supplementation.
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·PrevMed's website
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What started as a diet vacation for me turned into dietary debauchery. My sugar addiction acted up, I fell off the wagon, but I'm climbing back to gain control. Let's talk about sweets addiction, artificial sweeteners, a sugar buster called Gymnema Sylvestre. I'll also take questions about Prolon, Lp(a), niacin, and prediabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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An article about antisense oligonucleotides was recently published in the New England Journal of Medicine. While this new medication provides an 80% reduction of Lp (a) or lipoprotein(a), it appears to be not yet ready for primetime. Lp(a) is a variation of LDL, and some known ways to decrease it include statins, niacin, apheresis, and L-carnitine.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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While you can't stop aging or alter your family history or genetics, you can control many stroke risk factors. In this video, we'll list the common stroke risk factors (like physical inactivity & high blood pressure), the connections between atrial fibrillation and stroke, and some things you can do for stroke prevention.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Amidst the COVID-19 pandemic, should we close our schools? There are arguments in favor of and against that policy. We'll cover those things in this live session.
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This is day 4 of a personal Prolon FMD experience. I'm sharing the results. My blood glucose spiked again up to almost 200. After a bowl of Prolon soup? (23 grams of complex carbs)
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Sudden cardiac arrest is a Hollywood myth. According to a 2006 Harvard Heart Letter, while sudden cardiac arrest is often the initial sign of heart disease, most victims already got some cardiovascular issues. Here's the link to the article: https://www.health.harvard.edu/newsle....
Thanks to the excellent ways for screening plaque, cardiovascular inflammation, and insulin resistance, "metabolic storms" can be detected early to prevent a heart attack. I'll discuss this issue in this live session, and I'll also answer inquiries about CIMT, glucometer, vitamin K2, and intermittent fasting.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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At a press conference on December 4, 2020, the FLCCC Alliance has called on national health authorities to immediately review medical evidence showing the efficacy of ivermectin for the prevention & early treatment of COVID-19. Let’s discuss what ivermectin is, 2 studies about ivermectin, and the treatment protocol recommended by FLCCC.
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·PrevMed's website
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In the early days of the COVID-19 pandemic, doctors noticed something about people who became severely ill—Many were obese. In this live session, let's talk about why this is the case, and what steps one can do to prevent this.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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In part 1 of our "TG HDL ratio" Livestream, we introduced the concepts of HDL, triglycerides, LDL, remnant cholesterol, and how they are all connected to prediabetes/diabetes. In this part 2, we dive deeper into the TG HDL ratio, its importance, and how to improve this important cardiovascular marker.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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We just got an update today that the US has overtaken China (#1) and Italy (#2) in the number of confirmed cases. This makes lifestyle and behavior change more important. In this live session, Janice and I will discuss the COVID-19 lifestyle which includes social distancing and managing groceries and package deliveries.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Prediabetes and diabetes top the list of health conditions that could severely increase COVID-19 risk. Let's discuss what prediabetes is, what causes it, and how it affects COVID-19 severity. We'll also cover COVID-19 supplements (including zinc and quercetin), and the new 5-minute coronavirus test from Abbott Labs.
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·PrevMed's website
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While we are affected by the COVID-19 outbreak, we also see a silver lining from the crisis. I'm with Janice today, and we'll talk about a few of these good things that happened in COVID-19 times. Plus, updates on ACE inhibitors and ARB drugs, ivermectin as a potential COVID-19 treatment, and lower fatality rate.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Blood pressure medications ACE inhibitors and ARB drugs are in the spotlight nowadays. This was due to an initial finding that the COVID-19 virus sticks to the ACE2 receptor in the body, and that ACE-Is and ARBs affect ACE2 levels. However, the reports are conflicting—some say the drugs increase COVID-19 risk, while others say otherwise.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Dentists see peoples’ gums all day. As gum disease are early warning signs of prediabetes, dentists are already in a unique position to help prevent prediabetes and diabetes. In this video, let's discuss a tool/guideline that could help dentists deliver prediabetes care.
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·PrevMed's website
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You can't supplement your way out of a bad lifestyle, but that doesn't necessarily mean you should ignore supplements. In this video, let's talk about supplements for COVID-19: zinc and quercetin, vitamin D3, and vitamin C. Let's also talk about the potential use of the BCG vaccine against the coronavirus.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Most ER patients with COVID-19 had COVID pneumonia, even those without respiratory complaints or breathing problems. However, chest X-rays do show diffuse pneumonia, and the patient's oxygen saturation level was below normal. This makes a pulse oximeter a handy tool for detecting such "silent hypoxia." This topic was featured in The New York Times op-ed last April 20, 2020: https://www.nytimes.com/2020/04/20/op....
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Can COVID-19 herd immunity be achieved without a coronavirus vaccine? Possible. However, that would entail lots of people getting infected, some of which could suffer a fatality.
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This is day 3 of this week's Prolon experience. I experienced & shared a significant glucose spike - up to 180 - on my 1st meal (lunch) on day 2 of the Prolon diet. That hasn't happened before. I give follow-up and talk more about potential causes of the spike. We follow up with more Fasting Mimicking Diet facts. We will go into other things, too, as we have before. Tonight we cover Cancer and Fasting.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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With the new coronavirus strain discovered in the UK, there are many questions lingering on our minds. Should we be worried? Will the new strain affect current COVID-19 vaccines? What should we do now? Let's discuss these things in this live session.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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There's a recent report in Nature Nanotechnology about nanoparticles that can dissolve arterial plaque. These particles are expected to reduce cardiovascular risk with minimal side effects. In this live session, I'll briefly touch on that topic, plus I'll discuss inflammation, plaque formation, heart attack and stroke, ways to measure plaque, insulin resistance, metformin, a few supplements.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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In this video, let's talk about COVID-19 basics, what we should do, how the novel coronavirus is transmitted, how the novel coronavirus affects the lungs, plus other updates.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Children are also affected by COVID-19, and they are part of the transmission. In this video, we'll talk about COVID-19 and children, as based on this NEJM article: https://www.nejm.org/doi/full/10.1056.... Plus, I'll provide updates and answers about ACE Inhibitors; baby aspirin and NSAIDs; zinc supplements, quercetin, and ionophores; chloroquine and hydroxychloroquine; and the clinical trial of HIV antivirals Lopinavir & Ritonavir against the coronavirus.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Trials have been conducted in search of coronavirus medicine. One of these is Kaletra, an HIV antiviral drug made up of Lopinavir & Ritonavir. However, the trial found no therapeutic effect, as written in this NEJM article: https://www.nejm.org/doi/full/10.1056.... Let's discuss Kaletra and other "coronavirus treatments," like Remdesivir, Avigan, melatonin, zinc and quercetin, chloroquine, and hydroxychloroquine. Plus updates on COVID-19 reinfection, baby aspirin and NSAIDs, ACE inhibitors and ARBs, and the new coronavirus testing program we plan to launch in the coming days.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Let's discuss what we know so far about the ModeRNA, Pfizer-BioNTech, and Oxford-AstraZeneca COVID-19 vaccines.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Gum disease (like Inflamed, reddish, and bleeding gums) are early warning signs of prediabetes. And as dentists see peoples’ gums all day, they are already in a unique position to help prevent prediabetes and diabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
Let's talk about new updates on the science of COVID-19.
(1) A study published in Lancet has been hypothesizing increased COVID-19 risk with the intake of ACE inhibitors or ARB:
https://www.thelancet.com/journals/la....
(2) The European Society of Cardiology (ESC), however, stated that doctors shouldn't change patient's use of ACE inhibitor and ARB:
https://www.escardio.org/Councils/Cou....
We'll also talk about coronavirus testing, zinc supplements, antimalarial drugs chloroquine, and hydroxychloroquine, social isolation, and telemedicine as measures against the current COVID-19 pandemic.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
·PrevMed's YouTube channel
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Can vitamin C be used against COVID-19? The use of vitamin C against infection is an ongoing debate, rekindled recently by COVID-19. Studies are saying different things, particularly on vitamin C's effect on severe infection sepsis and acute respiratory distress syndrome (ARDS), which we'll discuss here. I'll also cover Harvard FAQs on COVID-19 and the CDC's coronavirus test guidelines.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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There's the popular notion that vitamin K2 moves calcium from arteries into the bone. This is a process that may adversely affect plaques that are already stable. But there are other plausible mechanisms on how vitamin K2 works.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Osteoarthritis (OA) & cardiovascular disease (CVD) are 2 of the most prevalent conditions affecting the US population. Although OA is the most common arthritis, we know very little about the relationship between OA and CVD.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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I'm covering David Sinclair's new book, "Lifespan: Why We Age—and Why We Don't Have To." Contained here are some interesting theories and discussions about aging and age-related diseases.
I also touched on the topics of Valter Longo's Prolon FMD (fasting-mimicking diet), vitamin K2 carboxylation and vitamin K2-dependent enzymes, inflammation tests (Hs-CRP, MPO, Lp-PLA2, and MACR), the secret life of fat cells, and niacin.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Inflammation panel (CRP, MPO, MACR, Lp-PLA2), OGTT (oral glucose tolerance test), and Kraft insulin survey—these are definitive tests to check whether you got insulin resistance and/or cardiovascular inflammation. If you want them done but don't know how where to get them, we have a new program for lab screening plus free webinars.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Let's talk about peripheral artery disease, ABI (Ankle Brachial Index), plaque, a bit about stress tests as well as the calcium score.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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We cover the recent New England Journal December 19 article, showing state-by-state projections for obesity for 2030. Half of us would be obese, and 1 in 4 would be morbidly obese! What do you think about that? I think we need to bend that curve!!
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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This is a YouTube Live event on the Fasting Mimicking Diet (FMD). I've had dozens of patients lose 30 pounds or more. Most of them do that with a combination of low carb and Time Restricted Eating. But very few take my advice on fasting. Why? It's hard. I know that. Valter Longo's product PROLON is an easy button for hardening your body to fasting. I'm doing an FMD event this week and covering the experience on YouTube Live.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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How does the body age? There are many theories about the aging process. In his new book "Lifespan: Why We Age—and Why We Don't Have To," longevity researcher Dr. David Sinclair discussed interesting concepts, like the information theory of aging and the so-called "zombie cells."
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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This is my weekly YT Live event. Tonight we talked about the new & first randomized clinical trial on Vit D and T2DM prevention. We also talked about limiting statin use to those with plaque, and finally, we talked about glycocalyx. It's where it's all happening.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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In this episode, we're going to be talking about high BMI (body mass index), weight loss, diabesity, obesity, prediabetes, diabetes, meal replacement diets, and fasting. We'll also answer questions from viewers about vitamin K2 and D3, Libre vs. Dexcom, and statins.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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I felt so good after the 5-day Prolon experience, I decided to change my schedule. I "water fasted" for 2 more days. Don't do this at home. I'll share why. First of all, "water fast" is in quotes. Here's why. I do usually have a bulletproof coffee in the AM. It includes 1/2 teaspoon of coconut oil and 1/2 teaspoon of ghee. That would technically make these days a "fat fast", not water fast.
Overall, everything continues to go well. But there was one problem. I woke up well-rested again this morning. (If you can sleep well during a fast, you'll probably do great!) But upon awakening, my blood sugar read 45. I confirmed it on my Freestyle fingerstick device. I felt fine, though. I obviously didn't operate machinery. And I only went downstairs. I had my bulletproof coffee and sat talking with Janice until my sugar came back up to the 60s.
In this video, we talk some about hypoglycemic episodes, what causes them, why they can be dangerous, and how to manage them.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Do patients with stable ischemic heart disease reaping tons of benefits from stents or bypass surgery? According to the latest ISCHEMIA trial, no, invasive procedures aren't bringing any substantial benefits in terms of preventing cardiovascular events. The message isn't something new, as this is what the COURAGE and ORBITA trials had been saying all along.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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In this episode, I'll first talk about Alzheimer's disease, insulin resistance of the brain, and T3DM (type 3 diabetes mellitus). I also touched topics/questions from viewers about Gymnema Sylvestre ("the sugar destroyer"), statins, CV inflammation, FH, magnesium, HIIT, and sitting as the "new smoking." By the way, we're currently ironing out our webinar pilot.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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The FDA released a statement about reports of metformin that's sold in the US containing NDMA (a carcinogen). This is in light of metformin sold outside the US having low levels of NDMA. The detected levels, though, are "within the range that is naturally occurring in some foods and in water."
FDA still recommends (and I agree with them) the continued use of metformin as prescribed while their investigation is ongoing. (In this live session, I'll also cover questions about CGM, CIMT, statins, gut biome, and insulin resistance.)
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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I had a patient come to me last week who didn't understand how he "cured" his insulin resistance. His OGTT and Kraft insulin surveys are done regularly, and he almost has full-blown diabetes. In this episode, I talked about what happened during his test. I will also answer questions about inflammation tests (particularly on high CRP values), vitamin K2, "diabesity," fat cells, and haptoglobin.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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You don't need type 2 diabetes to damage your eyes' retina. You're already at risk of diabetic retinopathy once you have prediabetes or insulin resistance. Diabetic retinopathy is also tied with other issues, like methylation and homocysteine, homocysteine and heart disease, methyl folate deficiency, folate vs folic acid, and the enzyme MTHFR. Confused? Let's connect all these pieces together in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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We'll review an article that shows the stability of calcified plaque. We'll also cover the Annals of Internal Medicine article that covered the case of a 17-year-old that is now blind from eating junk food. Believe it or not.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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·PrevMed's Facebook page
Let's talk about a paper titled "Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease." It was recently published in the New England Journal of Medicine last September 2019. In a nutshell, the study compares the long-term outcomes of patients who went through percutaneous coronary intervention (PCI) and stenting vs. those who went through coronary artery bypass grafting (CABG).
Also, we covered questions that currently interest the live viewers, like Hashimoto's disease, the dawn effect, continuous glucose monitoring, methylome, HIIT, and carb diets.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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If drusen (singular: druse) sound new to you, they are dots at the back of the eye. And they are related to insulin resistance as well as aging and inflammation. Apart from drusen, we'll also cover in this live session the topics of retinopathy, macular degeneration, methylation problems, folate, diabetic eye disease, and viewers' questions about vitamin K2, metformin, intermittent fasting, LDL, and supplements.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Janice and I sat down with Laura Freeman for this YT Live interview.
In the past, Laura created and ran "Laura’s Lean Beef," a company that raises and sells antibiotic-free beef. First, we cover the fascinating story of how she changed a tough, backward food market, bringing new considerations for health.
Now, she's in a new market: the CBD industry. As before, she's focused on health, quality, and measurable outcomes.
There is no question that CBD oil will continue to grow dramatically as an important supplement. There are many known effects, which we discuss in this video. But, as much as we know about the science of CBD, many questions remain. The science on the topic is emerging. In this video, we discuss Laura's story and a bit of CBD science. We'll cover more CBD science in future videos.
Laura's Mercantile's web site is below:
https://www.laurasmercantile.com/
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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We review two of the recent JAMA articles indicating that having a purpose in life is important for longevity. We also had a lot of questions about K2, autophagy, fasting, & CIMT.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Low carb vs keto, easy weight loss, ketones vs blood sugar, the FreeStyle Libre, Continuous Glucose Monitoring (CGM), the GKI ( Glucose Ketone Index), the DrBoz ratio, Dr. Bosworth & keto, the Warburg effect, CIMTs ( Carotid Intima-Media Thickness ) test & others.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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This is our weekly YouTube Live event. I start off by covering dysfunctional HDL and the many functions of HDL. We also got questions about K2, like whether it really does make sure that D3 works correctly. We talked about whether LDL is really good or bad. And we talked about Rapamycin, mTOR, fasting & autophagy.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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We covered a few topics, like a reversal of eye/kidney disease, the Esselstyn diet & heart attacks, the importance of BMI ( or RFM if you know it), and others.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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We cover the mechanism of CV Inflammation. Then we take a lot of questions, as we usually do. Then there is some information about the Webinar series - and other ways to access valuable information.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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This is an excerpt from our March 24 live stream. Let's discuss zinc and quercetin (as a proposed COVID-19 treatment) as well as other issues like hydroxychloroquine, social distancing, and coronavirus test.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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"Sleep is for the weak," some say, and I disagree. There's so much at stake with having a quality sleep that every one of us should have enough of it. This video is an excerpt from our recent Louisville conference. I'll discuss the basics of sleep and its connection to cardiovascular health, diabetes, insulin resistance, hormones, cancer, and telomere shortening.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Los Alamos National Laboratory scientists identified a new strain of coronavirus. This is more widespread and contagious than earlier strains, including the Wuhan coronavirus. Scientists focused on the D614G mutation which affects the virus's spikes. Here's the news article: https://www.msn.com/en-us/news/health....
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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The coronary artery calcium scan (CACS) detects and measures calcium in arterial plaque. Thus, it can only check for calcified plaque.
This podcast is an excerpt from our recent Louisville conference. Learn the basics of the coronary calcium scan and how to interpret your calcium score.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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An article titled "Effects of Intermittent Fasting On Health, Aging & Disease" was recently published in the New England Journal of Medicine. That article referenced another article about caloric restriction. In this last part of our 3-video series, David and I will discuss caloric restriction and how it differs from intermittent fasting.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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We released previously a Q&A video titled "How to Lower Your Calcium Score (Part 1)" where we listed several root causes of high calcium scores. We weren't explicit back then, but to lower your calcium score, you should know what causes it then do the fix.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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There are actually 3 different forms of folate—folate, folinic acid, and folic acid. Which one should you take? We will describe them in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Which type of arterial plaque is better—calcified or soft plaque? According to the Honda study, calcified/hard plaque is safer and more stable than soft plaque. Here are the crucial points:
(a) In ultrasound, "echogenic" appears as a solid, white mass. "Echolucent" would be transparent.
(b) Soft plaques are echolucent. 29 CV events happened in 112 patients with echolucent plaque (25.9%).
(c) Hard/calcified plaques are echogenic. Only 4 events happened in 103 patients without echolucent plaque (3.9%).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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What is the carotid IMT (CIMT) scan? Why is it such an excellent plaque screening test? This video is an excerpt from our recent Louisville conference. I'll discuss the basics of CIMT, the CAFES-CAVE study, and the certain limitations surrounding the CIMT test.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Statins are primarily known as LDL cholesterol-lowering medication. But statins (even in low doses) can decrease cardiovascular inflammation. Some statins also help regulate insulin resistance. All these combined effects make a low-dose statin a good component of a patient's regimen for reducing CV plaque.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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This is part 3 of our series on David Sinclair's new book, "Lifespan: Why We Age and Why We Don't Have To." We'll talk about 3 concepts—rapamycin, mTOR, autophagy. Rapamycin (an antibiotic) inhibits mTOR (a protein). mTOR inhibits autophagy. Autophagy is a natural process by which the body eliminates unnecessary components (like dead mitochondria). So, does rapamycin have an effect on aging and longevity? That's what we'll discuss in the podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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This podcast covers the sulfur-containing anti-oxidants N Acetyl Cysteine and Glutathione. Glutathione supplementation doesn't make it past the stomach acid. Acetyl Cysteine is better for supplementation. But cruciate sulfur-containing vegetables are best - asparagus, brussels sprouts, broccoli, etc. We also geek out on a little metabolic pathway discussion, showing relationships between the anti-oxidant vitamins A, C, E, Glutathione, and the Methylation pathways involving the B complex vitamins and homocysteine.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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The coronary artery calcium scan (CACS) detects and measures calcium in arterial plaque. Thus, it can only check for calcified plaque. In this video, know the basics of the coronary calcium scan and how to interpret your calcium score.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
·PrevMed's YouTube channel
·PrevMed's Facebook page
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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·PrevMed's Facebook page
LDL gets most of the flak for heart disease risks, but there's another type of cholesterol we should also be watching—remnant cholesterol. It's made up of VLDL (very low-density lipoprotein) and IDL (intermediate-density lipoprotein).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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This topic was requested by a viewer, Joe Isaacs. He saw an article indicating that PCSK9 inhibitors decrease plaque deposition. So he's asking why I don't use them. I do, but so far only for Familial Hypercholesterolemia patients.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Fasting is an important tool for managing weight and insulin resistance. I've recently started reading a few of Dr. Jason Fung's books on the subject. Long before that, though, I had a history of using fasting in my own weight management. This article provides helpful information on 3 critical hormones during the fasting process: insulin, ghrelin, and cortisol.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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This is the first video in a 2-part series on Gymnema Sylvestre. It's been used for centuries in Ayurvedic medicine for glucose control. We go into a little of this herb's history, uses, background, description, and safety/side effects.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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How many times do you go pee at night? If it's more than twice, you should get it checked out. And NOT by a gynecologist or urologist - a sleep specialist. You might have sleep apnea or sleep-disordered breathing.
How does that happen? Sleep has a huge impact on our hormones. Sleep apnea has even more impact. In addition to causing inflammation & catecholamine ( "fight or flight hormones like adrenaline), it also releases hormones that cause us to pee.
Nocturia (urination at night) is a screening tool for sleep apnea.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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The science is full of relationships between osteocalcin and diabetes. Osteocalcin is critical to bone growth and autophagy. It also appears to increase insulin sensitivity. And remember that vitamin K2 is required to activate osteocalcin through the process of carboxylation. Does this mean vitamin K2 deficiency can create insulin resistance? I don't know, but it's an interesting thought.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Gut biome and insulin resistance—is there a relationship between the two? How about non-nutritive artificial sweeteners? Do they affect gut biome or insulin resistance? Do they cause weight gain? From one of the Q & A sessions, I discussed stevia, erythritol, saccharin, and Gymnema Sylvestre.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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If you're curious about vitamin dosages, here's what I take for vitamin D3 and vitamin K2 MK7. For vitamin K2, I also add natto powder into my morning coffee.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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Vitamin K2 studies show varying results, with only the Rotterdam study significantly showing vitamin K2 benefits against plaque calcification. Vitamin K2, though, has other interesting aspects. It affects the mineralization activity of osteocalcin (a bone protein hormone). It also has pleiotropic effects against diabetes and insulin resistance.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Phytosterols - Cleveland Clinic says good for you. So does the AHA. But the French, German and English food and drug agencies say no.
What are phytosterols? Phyto means PLANTS. Sterol means an ALCOHOL (or ester) component added to CHOLESTEROL.
There are actually studies showing increased cardiovascular events in study participants with increased blood levels of phytosterols in the blood. There was no statement, however, that this came from dietary phytosterols.
The bottom line for me? I don't think there is enough evidence to take phytosterol supplements. But I also don't think there is enough evidence to warn patients off them.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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Homocysteine, folate, methylation, and monoamine metabolism in depression. Teodoro Bottiglieri et al. British Medical Jl
This is an old study. It's been cited over 500 times. Here's why. they took severely ( hospitalized) depression patients and controls: and
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it looked at methylation indicators in serum, red blood cells, and even cerebrospinal fluid;
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documented an inverse relationship between serum homocysteine and all other indicators for products of methylation, INCLUDING metabolite indicators of monoamine neurotransmitter metabolism.
In other words, there was strong evidence that the methylation metabolism failure was linked to depression.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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This podcast covers CycloDextrin. It's a new medication that dissolves cholesterol crystals. And it stimulates LXR -related genes. It's actually been shown clearly in lab mouse models to dissolve plaque. It hasn't been used in humans yet. But it has been shown to stop human immune cells from attacking plaque, again by the LXR pathway.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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There is a broad range of carbs in adult beverages. Beer is no exception. Until recently, there were not many low-carb options for beer. That has changed. There are now a lot of options. John L suggested a website (Daily Burn) that provided their list of the top 15 low carbs, low-calorie beers. This video lists their top 5. In reverse order, the top 5 are: 5. Busch Light - 3.2 gm carb 4. Michelob ultra - 2.6 gm carb 3. Beck's Premier light - 3.2 gm carb 2. Miller 64 - 64 calories 2.4 gm carb 1. Bud Select 55 - 55 calories. 1.9 gm carbs
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
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There is a wide range of opinions re: the best goals for A1c. Jenny Ruhl's book and website Blood Sugar 101 is an example of diabetics searching for prevention through tighter control. They have the "5% Club". This is a group of diabetics that maintain A1c levels less than 6%, " a level most doctors consider normal". They go on to talk about how this can be done safely- and how it increases safety long-term due to decreased arterial damage. The American Diabetes Association (ADA) standards are very different. 6.5% is considered an "aggressive goal", which should be done only for young people, not on meds other than metformin, focused on lifestyle. 7.5% is considered the standard and usual goal for "nonpregnant adults". And finally, 8% is considered a better goal for older diabetics, requiring more meds, and having lower life expectancy. There is actually scientific evidence for both sides of this debate. We'll cover that in other videos.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
·PrevMed's website
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A protein called MGP (matrix Gla protein) has a role in calcification. To do its action, the protein has to be activated by vitamin K2, and in turn, enables calcium removal from artery walls. This is a quick podcast to summarize specific MGP points.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin K2
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Policosanols are plant waxes and given for cholesterol or LDL problems. The logic for the mechanism is similar to phytosterols. Phytosterols are the plant version of cholesterol but maybe more healthy.
Policosanols are the plant version of fatty acids. They are for the most part safe. The major reaction concern may be increased bleeding. This is a concern since most people with CV inflammation or LDL problems are also taking baby aspirin or a blood thinner.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
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Recently, when I mention vitamin D to patients, they've begun asking, "which D vitamin?" There is another D vitamin: D2. It's plant-based and not nearly as potent. In fact, it's less than 30% as potent as vitamin D3.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin D
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
As a result of the AIM-HIGH study, doctors stopped recommending the use of niacin. But even the study author said it would be a mistake to stop using niacin as a result. But that's just what happened.
- https://www.youtube.com/watch?v=iy07edzuvmM
- https://www.nejm.org/doi/full/10.1056/NEJMoa1107579
Part of the standard medical response is true; you can't "supplement away a bad lifestyle". But the interpretation that niacin doesn't work was wrong. Unfortunately, too many of us are still living with that mistake - and dying with it as well.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on niacin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Intermittent fasting — alternating between periods of eating and fasting during the week — is a "new" weight-loss fad. But is it real and sustainable? Dr. Ford Brewer explains.
There are many versions of intermittent fasting-- weekly, daily, and monthly. Advocates claim many benefits ranging from improved athletic performance to weight loss, biomarker improvement, decreased inflammation, and even longer life. Are these real?
A little history: Intermittent fasting is not new. There is a long history and major cultural story here. And the hard science is becoming clear. It works. It even appears to prolong life.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This podcast is on CIMT. It measures the artery wall thickness. That's important. Why? Plaque actually enters the artery wall, not the inside (or lumen) of the artery.
Most heart attacks and strokes occur in arteries that were open. But plaques in the artery wall burst. When they do, the "hot" or inflamed liquid plaque touches the blood and causes a clot. If the clot is big and flows down to the heart, it causes a heart attack. Big clots that flow to the brain cause strokes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CIMT
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
How can you tell whether you are resistant to insulin or just don't make enough? There is a technique called the euglycemic clamp or the Whole Body Insulin Resistance Index (WBISI).
It involves intravenous insulin. (This can be dangerous. Don't try it at home.) Glucose is also given intravenously to counteract hypoglycemia. People (or animals) with insulin resistance require higher infusion rates of insulin and lower infusion rates of glucose to maintain a normal glucose level (euglycemia).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on insulin resistance
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The ASPREE study was a trial of aspirin in 20,000 healthy adults, age 70 and older. It was published in September 2018 in the New England Journal of Medicine.
Surprisingly, aspirin did not show a preventive benefit. Even more surprisingly, it showed an increased risk. And even more surprisingly, it was in cancer. Even the authors suggested that we look at these results with caution since there are meta-analyses which showed just the opposite.
There's one more surprise. The mortality rate was less than half of that predicted in the study. This is being seen in several studies, such as the ASCEND trials. Are we getting healthier in our old age? Is this washing out benefits of less powerful interventions such as aspirin and low-dose Omega 3s?
References:
- https://www.nejm.org/doi/full/10.1056/NEJMoa1800722?query=recirc_curatedRelated_article
- https://www.nejm.org/doi/full/10.1056/NEJMoa1805819?query=recirc_mostViewed_railB_article
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Garlic is safe. It's been used for 5000 years by historical civilizations including the Egyptians, Greeks, Romans, Native Americans, Japanese, and others. It's been used for health effects on the heart, arteries, cancers, respiratory system, and many others. There have been many epidemiological studies on its impact on health.
The National Institute of Health office for Complementary Medicine has a synopsis saying that it's clearly safe, but that evidence on the improvement of health is unclear. Garlic, like glutathione and N Acetyl Cysteine, contains sulfur. Allicin is the active compound. There are also other, non-sulfur- containing compounds (like FruArg).
This podcast covers the Nature magazine article on the impact of AGE (Aged Garlic Extract) on the inflammatory response triggered by Lipo-polysaccharide. According to the authors, it decreased 2/3 of the inflammatory mRNA gene expression. FruArg decreased 55%.
References:
- https://759241a66b89-003789.vbulletin.net/forum/supplement-questions-and-comments/493-chondroitin-sulfate-and-aged-garlic-extract-for-reducing-arterial-inflammation
- https://www.nature.com/articles/srep35323
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
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ACCORD was a large (over 10,000 subjects, 71 centers) trial of lower A1c levels in people with advanced diabetes and pre-existing cardiovascular disease. Over 32% were already on insulin; their mean BMIs were over 30.
The intensive study group (goal A1c less than 6) had fewer nonfatal MIs. However, they had a greater overall death rate. Deaths occurred in cardiovascular categories as well as others. The intensive study group had far more people gaining over 10kg. In other words, the attempts at lowering A1c were made with medication, not lifestyle.
This has lead to a fear of lower A1c goals for everyone, and even using lifestyle. What it really meant was you shouldn't try lowering the A1c of advanced diabetics using meds alone.
- (ACCORD trial link) https://www.nejm.org/doi/full/10.1056/NEJMoa0802743
- (significance - ADA/AHA standards) http://care.diabetesjournals.org/content/32/1/187.figures-only
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You can actually estimate arterial age using ultrasound technology of the arterial wall. Heart attacks and strokes occur "downstream" of an artery wall with a soft, inflamed plaque. Calcification indicates an old plaque that has stabilized. Carotid intima-media thickness (CIMT) measurement allows estimation of arterial age.
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- PrevMed's article on CIMT
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This podcast explains and balances the risks and benefits of statin use. There are risks from myopathy (muscle tissue breakdown), the advancement of diabetes, and even a potential risk of stroke.
So, why do doctors routinely recommend statins? Because they save lives.
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- PrevMed's article on statins
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Most doctors prescribe statins to lower LDL (or "bad" cholesterol). However, that's probably not how statins prevent heart attacks and strokes. It's more likely due to an impact on cardiovascular inflammation.
What is cardiovascular inflammation? Inflammation is similar whether it's causing arthritis, skin disease, or inflammatory bowel disease: inflammation is the body's attempt to correct a problem. The immune system sends antibodies and immune cells. Immune cells release enzymes to "digest" tissue that should be there. In the artery wall, that tissue is plaque. Inflamed plaque is unstable. It can leak into the bloodstream and cause life-threatening clot formation.
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- PrevMed's article on cardiovascular inflammation
- PrevMed's website
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Livalo (pitavastatin) is a newcomer to the statin market. It brings many advantages with improvements in LDL, HDL, muscle damage side effects, and even glucose/HgA1c values.
So why have I not given it? My treatment priority is inflammation, the immediate cause of heart attack and stroke. With statins, my priority has not been LDL and DM treatment. Livalo has no known impact yet on inflammation.
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Continuous glucose monitoring has many advantages over conventional glucometers that incorporate lances and testing strips. Just how accurate are these new continuous devices and how reliable is the information we obtain from them?
About John Lorscheider - John is a frequent contributor. He’s also a PrevMed patient. Like most of us, John’s family and personal history includes significant cardiovascular risk.
John came from a technical background and spent his entire career in providing engineered fluid process systems and equipment to industry, as well as performing root cause failure analyses for his customers.
His own study and research made it clear he wasn’t getting the whole story about prevention from his docs. They just didn’t know. So he’s been in several roles of running prevention medical groups to help further the science.
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Malmo and associates from Sweden published an article in Circulation in Jan 2016. It was the report of a randomized clinical trial of HIIT in atrial fib patients. They used a loop recorder looking for episodes.
There were 51 patients with significant AFib. They were symptomatic. They had all been referred for ablation. The mean BMI was 28. They were randomized to 12 weeks of HIIT. The control group was told to do whatever they usually did, whether it included exercise or not.
Those with HIIT training had fewer episodes of atrial fib. Also, the episodes were shorter and less intense. They also lost 5 pounds more weight, had improved cardiac function and improved lipid/cholesterol indicators.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on atrial fibrillation
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The Malmo study was a randomized clinical trial of 51 patients with significant atrial fibrillation, referred for ablation. HIIT resulted in decreased frequency and intensity of episodes of atrial fib, weight loss, improved lipid profiles.
Elliott and others were asked to do this editorial because of their own work in the area. They review the importance of atrial fib and the importance of exercise in the prevention of atrial fibrillation. They also discussed the J curve dilemma resulting from the increased risk of atrial fib among endurance athletes. They demonstrated in their own study of over 300 atrial fib patients a 9% decrease in atrial fib episodes for every 1 metabolic equivalent of exercise tolerance on a treadmill.
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- PrevMed's article on atrial fibrillation
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Patients often come in with reports of pulmonary nodules (solid tissue in the lungs). These are first seen usually in a chest X-ray or a CACS (coronary artery calcium score). The patients are worried, afraid of cancer. What indicates cancer? Size, shape, fluid, calcification pattern, the rest of the lung, and other criteria.
This patient, like the vast majority, was advised to wait for months to repeat the CT. That's a challenge for the patient. But it's actually a good sign. Being asked to come in for further work-up is more challenging.
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This fDNA test was much anticipated. Instead of looking simply for blood from a polyp, this was a test for the adenoma or cancer DNA. It actually could have worked better. The sensitivity is improved over other at-home colon cancer tests.
However, the price is over $600 each time. At that price, no one's likely to do repeated studies. They're only recommended every 3 years. Even at that 3-year interval, it's still over $1,000 over a 10-year period.
That's why very few standards, guidelines, or recommendations include fDNA (Cologuard) as a front-line option. They've just priced themselves out of being a practical option. Adding other testing technology improves the sensitivity but at great cost for increased false-positive tests.
- http://www.latimes.com/business/la-fi-lazarus-20140822-column.html
- https://www.webmd.com/colorectal-cancer/home-test-colon-cancer-cologuard#1
- https://www.ncbi.nlm.nih.gov/pubmed/27305422
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There are 2 basic differences between LDL and HDL: content and protein type. LDL has 25% or less protein. HDL has 50% or more protein. In addition, the proteins are slightly different. HDL's protein is called A1; the protein in LDL, VLDL, and other large lipoprotein groups is apo B.
Why the prefix "apo"? Apo as a prefix simply means "part of". And lipoproteins are the proteins that our bodies use to safely transport fats, oils, and cholesterol.
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I've had requests from viewers to see what I eat. This podcast is about home foods. I have gone from 6 servings of salmon/week up to about 10. By far most of my calories are from olive oil. (Bertolli's the best kind available to me). I saute Brussels sprouts, brocolli, and mushrooms.
I usually eat only 1 or 2 dishes if I'm eating alone. And it's usually sauted vegetables. It reminds me of Gundry's statement, "food is a vehicle for getting olive oil into your mouth."
I come from challenges around foods, including a father that weighed over 350 pounds ( at 5'10"). Holidays were episodes of being surrounded by cakes, pies, fudge, and other desserts. And I was a high birth weight baby - 10.5 pounds.
I have replaced the high grains in my previous high-carb diet with biscuits I'm making out of psyllium fiber. Beware - they're bluish/black! After a couple of years of intermittent fasting (6/1) and 30 years of high-carb, plant-based diet, I switched to low-carb, plant-based diet.
I added mimicked fasting and even metformin due to insulin resistance. I developed a couple of hypoglycemic episodes. Those are dangerous at worst and unpleasant at best. So I stop metformin (or if I happen to be taking pioglitazone at the time, I alternate every few months) when I go onto significant caloric restriction.
By far the largest single source of calories now is vegetables sauteed in olive oil.
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The Lancet Study, based on the ARIC trial, actually speaks about the diet of younger people and people that do not have diabetes or CV disease.
- https://www.thelancet.com/action/showPdf?pii=S0140-6736%2817%2932252-3
- https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext
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Inflammation was shown to be an independent risk factor for heart attack and stroke for years. Even the MRFIT study and Framingham over 20 years ago showed that elevated CRP (C-reactive protein) causes heart attack and stroke.
Paul Ridker and Gavin Blake noticed in the WOSCOP trial that the decrease in heart attacks and stroke were higher than you'd expect from the impact on LDL and the minor impact on the size of the plaque. Also, they noticed an improvement in the major available marker for inflammation (at that time): CRP. So they designed the JUPITER study and published it in the New England Journal. They selected only people with low LDL and high CRP. They had a big decrease in heart attack and stroke.
Paul Ridker made the headlines in August 2017 with the topic of inflammation and CV risk. The study was CANTOS, using the major anti-inflammatory drug Ilaris. It made a big decrease in not only heart attack and stroke but even with cancer.
Unfortunately, the number of lives saved from prevented heart attacks, strokes, and cancer were all given back with increased deaths due to serious infection. That's not surprising; Ilaris is a heavy-duty anti-inflammatory used to stop inflammation associated with major auto-immune diseases. That level of anti-inflammation is likely to cripple the body's immune system. In these cases, it resulted in death due to serious infection.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CRP & other inflammation tests
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Stem cell treatment is the big buzz now in orthopedics. I had a family member with great results with the arthritis of her hand. There are a lot of companies now providing stem cell treatment. Most of them offer stem cell treatment for stroke as well.
There are reputable (and not so reputable) companies providing stem cell treatment now for arthritis, stroke, and other disabling conditions. Stroke is the #1 cause of disabling disease in the US. It affects women more than men, and those greater than 65, at least 75% of the time. Stroke is now the #5 cause of death, down from #3 due to improvements in the major cause of stroke-- hypertension.
Atrial fibrillation is growing in importance. It's become clear that we need to improve the detection of paroxysmal (unknown, occasional) atrial fib. It's also clear that we need to have better methods of detection. I use iKARDIA, Alive Cor. (And I have no financial connection to this product.) I use it myself. I have 4Q25 the atrial fib gene. When I get a flutter, I check a rhythm strip on my iPhone.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke & atrial fibrillation
- PrevMed's website
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Ford & John discuss all those tricky carbs that sneak into your diet, such as:
- fruits;
- "healthy" vs fructose loads;
- legumes;
- lentils & garden peas;
- kidney beans;
- nuts (like cashews & others);
- maltodextrin.
We also discussed sugar alcohols & fiber.
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The video "What The Health" preaches the gospel of a plant-based diet. But people can sustain very unhealthy diets using plants only.
Meanwhile, there are other public sources of information, like "Fat Chance" by Robert Lustig and "Why We Get Fat" by Gary Taubes. These focus on sugars and carbs, based on the hormonal theory of weight gain. Basically, this theory indicates that carbs stimulate insulin. Insulin stops our process of fat-burning. We get hungry. And we eat more. And we get fat. There is a lot of good science supporting this theory, by the way.
Whether it's carbs or fats, plants or animal sources, obesity kills. And diabetes kills. Like obesity, aging is a risk factor for both death and diabetes. We can eat the wrong foods even though plant-based. We have to be a little smarter than that.
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There are a lot of blood thinners in the herbal medicine list, like garlic, nattokinase, ginger, cinnamon, cassia, vitamin e, Ginko biloba, grape seed extract, cayenne, aspirin, apple cider vinegar, and cod liver oil. But most of these are antiplatelets, not anticoagulants. Anticoagulants have been shown to be more effective in terms of prevention of strokes.
Safety is also an issue. The strokes we're preventing are infarction, embolic, or ischemic strokes. So, we decrease the formation of blood clots. Unfortunately, that also increases the risk for serious bleeding or hemorrhage, such as hemorrhagic strokes.
The research has been clear for over 20 years that anticoagulants seem better than antiplatelets for stroke prevention. And most docs will go with the researched recommendations. These days the researched recommendations are leaning more and more toward the NOACs (new oral anticoagulants).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke & atrial fibrillation
- PrevMed's website
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This is another issue raised by Jenny Ruhl in her book Diet 101. It involved a study by Kasim-Karakas of PCOS patients. They compared hormone responses to glucose vs. protein dietary challenges. Ghrelin stabilized after the protein challenge. However, ghrelin increased again starting at 3 hours after a glucose challenge. Evidence indicates that low-carb, high-protein meals decrease the fluctuation of blood glucose and ghrelin as well as other hormones.
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In order to interpret your cholesterol tests, we need to understand lipoproteins. If fats and oils are released into the bloodstream, they would cause major damage if not for lipoproteins. Fats and oils would coalesce into large "bubbles" or emboli. These emboli would cause damage like heart attack if not controlled. Lipoproteins keep the fats and oils from forming large, or embolic, particles.
LDL (low-density lipoprotein) and HDL (high-density lipoprotein) are mostly the same except for the portion of protein. HDL has 50% or more protein. LDL has 25% or less protein. HDL is, therefore, like an empty dump truck, able to carry LDL away from the artery wall. LDL is like a full dump truck, spilling and leaving LDL in the lining of the arteries. That LDL deposition is plaque formation.
Other particles (lipoprotein) get larger and are carry even more fats and oils. These are called IDL (intermediate density lipoprotein) and VLDL (very low density lipoprotein) all have more fats and oils (cholesterol and triglycerides). The particles that are the most likely to get caught in the artery wall have mostly fat (LDLs), but they are small & dense enough to slip between cracks in the intima. They're called sdLDL, which stands for small, dense LDL.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on cardiovascular inflammation
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You don't have to be on insulin or sulfonylureas or DPP4s/Victoza to have a hypoglycemic episode. Such an episode can happen at significant, even dangerous levels. And they are dangerous, causing arguments, wrecks, and even seizures.
I'm on metformin. Metformin doesn't cause hypoglycemia. Insulin, sulfonylureas, and other meds do that. But metformin makes it difficult for your liver to raise your glucose if it does go low.
Alcohol does the same thing. Does that give you some perspective on your experience if you've ever had a "hangover" that improved from eating or drinking calories?
Because of the adrenaline/epinephrine and the fact that I've been on low-carb diets, I couldn't eat carbs. But I was able to eat cheese and then later an omelet.
This is a critical warning for baby boomers. I was born with a weight of 10.5 pounds. My family thought I was just a fat, happy baby. Since then we've found that babies weighing over 8.5 pounds at birth are at a greatly increased risk of diabetes. There is a common belief that prediabetic patients are at increased risk for diabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin
- PrevMed's website
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Prediabetes is often called insulin resistance. Glucose transporter proteins (insulin receptors) located in the cell walls can be opened by insulin. High-intensity exercise can also open glucose transporter proteins for up to 48 hours. That's why exercise has to be more than once per week. 3 times 48 equals 6 days.
Metabolic proteins involved with insulin resistance (like MTOR, AMPK, etc.) are often involved in this process of insulin receptor function. Mimicked fasting, lifestyle, and epigenetics--all these are ways to make sure that these insulin receptors function.
One final point--stress can cause insulin resistance. Cortisol (the stress hormone) has a negative effect on insulin receptor function.
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- PrevMed's post on insulin resistance
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This podcast covers a great science review article by 2 prominent authors in the fasting space: Valter Longo and Satchin Panda. This part covers some of the original science showing that fasting works in terms of both longevity and biomarkers for chronic diseases.
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There was a lot of reaction to a recent post on vitamin K2. Bambi Able walked us through not only her own story but some great comments about the science and her logic. Originally, she said, "Maybe it's not THE answer, but they are a non-toxic idea."
That was actually my summary of the science until John Lorscheider weighed in with science indicating that calcium might actually be more than a marker of plaque stability. It might, according to John, actually be like mortar contributing to plaque stability.
According to these citations supplied by Bambi, there is some (although not very strong) evidence that MK-7, 8, 9 actually decrease calcium and may even decrease CV events.
- https://www.ncbi.nlm.nih.gov/pubmed/28797404
- https://www.ncbi.nlm.nih.gov/pubmed/19179058
- https://www.ncbi.nlm.nih.gov/pubmed/26295257
So clearly, further research is needed. But based on the information cited by John, maybe we should "let sleeping dogs lie."
I agree. I'd also say that the big issue is getting ignored. Most of the patients I see are focused on unproven supplements (such as K2) while ignoring blood glucose and insulin values. They're "fiddling while Rome burns."
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- PrevMed's article on vitamin K2
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Dale Bredesen is the author of the book "The End of Alzheimer's." He is an internationally recognized neurologist specializing in dementia and Alzheimer's disease prevention. He says he's actually reversing Alzheimer's. He's using well-researched treatments as well as less-researched treatments and preventive.
Besides the science and medicine, he got 2 major concepts:
- Functional medicine: Some of this isn't totally researched. But let's be functional and provide anything that can help the patient;
- "36 holes in the roof": There are at least 36 causes of dementia. Therefore, the "holy grail" of a single medicine or cure is a pipe dream destined for failure. Yet we continue to waste $ trillions on looking for that "magic bullet."
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on Alzheimer's
- PrevMed's website
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L-carnitine is known as a fat burner, a "jet fuel" for bodybuilders. It's also known as atherogenic. Its biggest dietary resource is meat. When meat is ingested, gut bacteria ferment it and form TMAO (Trimethylamine N-oxide), a known atherogenic.
But there is evidence that it actually helps lower lipoprotein (a) or Lp(a). There was a strong meta-analysis in Scientific Reports of 2016 using robust Cochrane meta-analysis techniques. It indicated that there is actually some decrease in Lp(a). The "dropped study" analysis indicated that the L-carnitine may be used in conjunction with statins (simvastatin in this study).
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Dr. Joseph Mercola's book "FAT FOR FUEL" is a fun book with a lot of information. It reflects a large change in our culture around diet, from low fat to high fat.
This is somewhat revolutionary. When TIME magazine featured cover articles on Ancel Keys in 1961, Keys was the driving force behind the decades-long low-fat diet culture. But in 2014, TIME then featured a cover article on eating butter for health.
Dr. Mercola recommended a dietary fat content of 70-80% of calories. This type of diet, though, can be dangerous to the 1-in-5 individuals with ApoE4 genetic components. It would increase the risk for heart attack, stroke, and especially senility.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article about saturated fats
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This starts with my own personal cholesterol test. And it goes through a rapid analysis of the major components of the test. You'll have a great picture in your mind at the end of what these concepts mean: lipoprotein, cholesterol, good and bad cholesterol, LDL, HDL, Lp(a), ApoB/ApoA1, ApoE, TG/HDL, and sdLDL.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
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The fact that the obesity epidemic is even hitting the teenage demographic proves the rule that teens usually tend to be thinner, more active, and can even eat more than middle-aged people. It's about hormones. If hormones can create this difference among age groups, can't hormones create weight problems among individuals?
Here's the mechanism for hormonal or insulin obesity. Carbs in the diet (not fat or caloric overload) causes insulin increase. If the individual has several high-carb meals and snacks daily, there is a greater time period every day when the body's fat-burning mechanisms are shut down. This, according to the insulin theory of weight gain, causes fat deposition and eventually, obesity.
Let's consider TAME, the only study approved by the FDA for anti-aging. TAME (Targeting Aging with Metformin) was designed by large groups of gerontologists. These are doctors that work with aging on a daily basis. Their consensus was that breakdown of glucose metabolism mechanisms was the most common cause of what is currently considered "normal aging".
What's the connection between the insulin theory of obesity and metformin? They both concern hormonal breakdowns in glucose metabolism. In addition, they bring up a practical consideration: Is there a treatment?
Yes. Metformin, as discussed, slows the breakdown of glucose metabolism, particularly with some enzymes such as MTOR and AMPK. But metformin has also been found to be an effective treatment for a couple of key patient groups.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin & weight loss
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Strokes are the #1 cause of significant long-term disability, the #5 (or #3) cause of death. 55,000 more women have strokes each year. It's decreasing due to better management of blood pressure - the biggest risk factor.
But the new challenge in stroke prevention is atrial fibrillation. Paroxysmal (occasional, undiagnosed) atrial fib is becoming recognized as one of the new leading causes of stroke. So, it is becoming far more important to look for atrial fib.
Now, it has become clear that there are better ways to prevent a stroke if medication is needed. Aspirin does help. But Plavix is better. Warfarin or Coumadin is even better. But Elliquis, Xarelto, dabigatran--the NOACs (new oral antiCoagulants)--are even far more effective at preventing a stroke.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke & atrial fib
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
A viewer asked whether vitamin K2 is a reasonable tactic for arterial plaque reduction, and if yes, how much vitamin K2 should be taken. I tackled those topics in this podcast, and I also mentioned vitamin K2's connection with insulin resistance and enzymes like MGP and osteocalcin.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin K2
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The book “Blood Sugar 101” by Jenny Ruhl is excellent. It is a summary of Ruhl's award-winning website. She has done a lot of research for this website and uses this for her books. She's not a medical professional. This cuts both ways. She places excellent criticism of medical researchers, like the UKPD study, saying incorrectly that diabetic control doesn't preserve eyes and other tissue.
On the other hand, the summaries of medications can be a little simplistic. She sees metformin as great, insulins as necessary, and everything else as poisons. That tends to give no options for those of my patients that just can't tolerate metformin. All prescription drugs have their problems. That includes metformin as well as pioglitazone, the GLiPs, SGLT2 inhibitors, etc.
She provides a major contribution to low-carb dieting, especially for diabetics and prediabetics. The rest of the world sees the metabolic advantage of low carb diets as great for weight loss. She and Richard Bernstein see a different issue; it's the key for diabetics and prediabetics to retain normal glucose values.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In this podcast, we cover several components of cholesterol test results. We start with key questions, like:
- What are lipoproteins (cholesterol values)?
- Why do lipoproteins even exist?
- What's the difference between LDL and HDL?
We end up explaining how the most important clues for heart attack & stroke risks found in cholesterol (or lipid) tests actually point to our old friend: insulin resistance, prediabetes, metabolic syndrome.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Aseem Malhotra is an interventional cardiologist. He takes swipes at:
- Stents for prevention don't work.
- Statins don't work.
- Saturated fats aren't harmful.
It may surprise you to note that I think almost all of what he says is right. Almost.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article about stents
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- PrevMed's YouTube channel
- PrevMed's Facebook page
A viewer once said, "My cardiologist (a leading cardiologist at Cedars-Sinai) said this is not possible... You can't (reverse CV plaque)." So I must be a crazy YouTube doc, right?
Wrong. It's true that plaque reversal is uncommon. And "drinking 1 cup a day" of anything alone is not going to do it. But the science (like JACC - the Journal of the American College of Cardiology) is full of studies of measure plaque reversal.
http://www.onlinejacc.org/content/66/5/495
This podcast mentions several other articles as well but shows a key image from this JACC study. Doctors, patients, & web influencers really need to study the science more. When they don't, we end up with too much death & disability due to CV inflammation, which is usually in turn due to insulin resistance.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on arterial plaque reduction
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Even TIME magazine featured a cover in 2004, blaming inflammation for heart attack, stroke, Alzheimer's cancer, and other chronic diseases.
Dale Bredesen in his book END OF ALZHEIMER'S, Brad Bale and Amy Doneen in their book BEAT THE HEART GENE, and others have their recommendations for biochemical tests for inflammation.
Paul Ridker, MD at Brigham & Women's, is considered by many to be the father of chronic inflammation. He recently made headlines with the CANTOS trial. He looks simply at hsCRP.
Bredesen adds albumin amounts and ratios. So do Bale and Doneen. Both added TNF alpha and IL6 previously. Both have also looked at Omega6:3. Bredesen looks at glutathione as well.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on inflammation tests
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
You can't stop aging or alter your family history or genetics. But you can control many stroke risk factors.
In this podcast, let's discuss:
- What is stroke?
- The 10 most significant stroke risk factors;
- How to prevent stroke (Exercise & 6 more ways of stroke prevention);
- What is atrial fibrillation?
- DIY atrial fib detection
- Atrial fib prevention
Here are the articles used for discussion:
- https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(10)60834-3/fulltext
- https://www.health.harvard.edu/womens-health/8-things-you-can-do-to-prevent-a-stroke
- https://strokeprevention.info/risk-factor-psysical-inactivity/8-facts-on-exercise-and-stroke-risk/
- https://www.stroke.org.uk/sites/default/files/exercise_and_stroke.pdf
- https://pubmed.ncbi.nlm.nih.gov/19254604/
- https://pubmed.ncbi.nlm.nih.gov/20929415/
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke & atrial fib
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I used my own labs from the March 2019 Orlando event, The Healthy Life Summit, to show how to assess insulin resistance or prediabetes. We even cover how to avoid some pitfalls, such as relying on fasting blood glucose or hemoglobin A1c.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I've done several YouTube videos for vitamin K2. If not for a patient who asked the question, I would have forgotten to mention that I do take vitamin K2.
In this podcast, I'll tell what vitamin K2 I take, why I take it, and how I take it.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin K2
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Several trials are coming out now regarding the primary prevention of heart attack and stroke. This podcast contains the reaction of the medical community to the ASCEND TRIAL, published in the New England Journal in Aug 2018.
The trial showed a significant decrease in heart attack and (ischemic) stroke. But it came at the cost of increased bleeds (GI, brain, & eye). There is a debate now regarding whether the guidelines should be changed.
- https://www.nejm.org/doi/full/10.1056/NEJMoa1804989
- https://www.medscape.com/viewarticle/901212
- https://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/aspirin-to-prevent-cardiovascular-disease-and-cancer
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke prevention
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There are several techniques currently used to screen for arterial plaque. The list includes the Framingham risk score, stress test, coronary angiography, coronary artery calcium score, ankle-brachial index, and CIMT.
Each of these techniques, though, has pros and cons. In this podcast, I'll give a brief overview of these plaque measurement techniques.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
When a diagnosis of insulin resistance or metabolic syndrome is given, patients often want to know which is more effective: lifestyle or metformin.
The NEJM published landmark research in 2002 showed that lifestyle is clearly more effective IF it involves intense lifestyle changes. This included 1-on-1 training for 6 months, a 7% weight loss, and over 150 minutes per week. We also found that HIIT, resistance training, and low carb diets are also especially effective for preventing diabetes, heart attack, stroke, erectile dysfunction, and dementia.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
TAME (Targeting Aging with Metformin) aims to slow the aging process. It has been developed and approved by the National Institute of Aging and the FDA. The principal investigator, Nir Barzilai, is excited about changing the paradigm and getting big PHARMA to actually fund research for drugs (like metformin) for anti-aging.
Getting older is associated with heart disease, kidney disease, cancer, dementia, among other things. This is where metformin comes in. It helps slow down the major biochemical challenge of aging: glucose metabolism. Enzymes like insulin membrane receptors, mTOR, AMPK, and SIRT1 are implicated. And they are positively impacted by metformin.
Metformin is cheap (free at many pharmacies now). It's been used for decades. It's popular (the #1 oral drug for early type 2 diabetes). And it's safer than you think. Some medical sites (like Mayo) still incorrectly list lactic acidosis as a problem with metformin. But look up the multiple Cochrane analyses on this.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
New evidence regarding the impact of supplementation with PQQ (pyrroloquinoline quinone) appeared this June 2018. Using standard lab animal models, this showed:
- significant improved cognitive performance;
- decreased reactive oxygen species;
- decreased inflammatory markers.
Here's the link to the article: https://www.nature.com/articles/s41598-018-26962-9.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Magnesium is important to over 300 known metabolic pathways. Magnesium sulfate is given to prevent and stop the seizures and high blood pressure associated with eclampsia, pre-eclampsia, HELLP syndrome, and alcohol withdrawal syndrome.
There is much evidence that most of us have magnesium deficiency. Estimates range from 30% to over 50%. This deficiency is more prevalent in chronic diseases such as diabetes, inflammatory diseases, and alcohol dependence.
The most common forms are magnesium sulfate and citrate. There has been some press recently about the neurologic and mental health advantages of magnesium threonate. I recently made a fool of myself by being arrogant and making an assumption that threonate was simply a ploy to sell more supplements.
A viewer patiently and politely asked me to investigate more deeply. I did. And I apologized. She was very gracious. And I bought myself some magnesium threonate supplement. I'm taking it now.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on magnesium
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I tell the story of a friend that had a slightly positive Lp-PLA2 test. He was very worried about CV inflammation. I was able to put him at ease by describing the rest of his cardiovascular inflammation panel.
This focus on CV inflammation started, and is still being researched, by Paul Ridker MD at Harvard. Here are the other tests we review: myeloperoxidase (MPO), high-sensitivity C-reactive protein (hsCRP), and microalbumin creatinine ratio (MACR). You can find a lot of this at the following link from Cleveland Heart Labs (CHL), which was recently purchased by Quest.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on inflammation tests
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This is another issue raised by Jenny Ruhl in her book Diet 101. It involved a study by Kasim-Karakas of PCOS patients. They compared hormone responses to glucose vs. protein dietary challenges.
- Ghrelin (the hunger hormone) stabilized after the protein challenge.
- However, ghrelin increased again starting at 3 hours after a glucose challenge.
Evidence indicates that low-carb, high-protein meals decrease the fluctuation of blood glucose and ghrelin as well as other hormones.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Coronary plaque begins as a soft and unstable plaque with a thin fibrous cap. It is often inflamed too. It has the ability to rupture and cause cardiac events. How do we take that type of higher-risk plaque and convert it to lower-risk, hard, and stabilized plaque?
About John Lorscheider - John is a frequent contributor. He’s also a PrevMed patient. Like most of us, John’s family and personal history include significant cardiovascular risk. John came from a technical background and spent his entire career in providing engineered fluid process systems and equipment to industry, as well as performing root cause failure analyses for his customers. His own study and research made it clear he wasn’t getting the whole story about prevention from his docs. They just didn’t know. So he’s been in several roles of running prevention medical groups to help further the science.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on arterial plaque reduction
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Over half of us develop insulin resistance between 50 and 60 years. High-intensity interval training has shown to be the best type for preventing this.
But many of my patients are in their 50s, 60s, 70s. Many of them are walkers only. They are surprised to find that they, too, can do interval training.
It's not your current performance, it's your willingness to push forward. Most walkers can find hills or stairs. Treadmills and ellipticals on resistance work. Even wheelchair-bound can do handcycle ergometers. The details of intensity/recovery, total numbers of intervals, and time in the gym (less than 30 minutes) are covered.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Saxenda is the new name given to diabetes drug Victoza in 2014, when manufacturer Novo Nordisk discovered that Victoza can also cause weight loss. Both brands are under the generic drug liraglutide.
Liraglutide belongs to a larger class of drugs called incretins. These were discovered by Dr. Eng from the saliva of the lizard called the Gila monster. These have become blockbuster drugs with revenue rising to $3.5 billion in 2015.
In terms of advantages, these meds appeared to save the beta cells of the pancreas and prevent the hypoglycemic episodes seen with insulin. (However, the impact on the beta cells may have turned out to be the source of biggest risk--pancreatitis.) The LEADER trial showed improved cardiovascular outcomes for diabetics taking liraglutide. So, there are clearly opportunities, but risks as well.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on liraglutide/Victoza/Saxenda
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This is a summary of the scientific literature on coenzyme Q10 (CoQ10, ubiquinone) and its reduced form ubiquinol.
It's clear that CoQ10 is safe, important, expensive. That it's a key component of animal cell respiration and drives over 90% of our energy production. It's depleted during disease states, such as heart failure, stroke, and cardiovascular inflammation.
CoQ10 is also depleted by statins. But what's not clear is whether improving levels of CoQ10 actually improve athletic performance and disease outcomes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on coenzyme Q10
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I have a viewer that is taking berberine INSTEAD OF METFORMIN. Is that wise?
There is some quality research available suggesting a 2 point drop in HgA1c. There are multiple mechanisms: AMPK-protein kinase activity, improve insulin sensitivity, protect beta cells (pancreatic islet cells), and improve triglycerides (probably due to decreased glucose).
Let's discuss further this topic in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on berberine vs. metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There are a lot of blood thinners in the herbal medicine list, like garlic, nattokinase, ginger, cinnamon, cassia, vitamin e, Ginko biloba, grape seed extract, cayenne, aspirin, apple cider vinegar, and cod liver oil. But most of these are antiplatelets, not anticoagulants. Anticoagulants have been shown to be more effective in terms of prevention of strokes.
Safety is also an issue. The strokes we're preventing are infarction, embolic, or ischemic strokes. So, we decrease the formation of blood clots. Unfortunately, that also increases the risk for serious bleeding or hemorrhage, such as hemorrhagic strokes.
The research has been clear for over 20 years that anticoagulants seem better than antiplatelets for stroke prevention. And most docs will go with the researched recommendations. These days the researched recommendations are leaning more and more toward the NOACs (new oral anticoagulants).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stroke & atrial fibrillation
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
When a diagnosis of insulin resistance or metabolic syndrome is given, patients often want to know which is more effective: lifestyle or metformin.
The NEJM published landmark research in 2002 showed that lifestyle is clearly more effective IF it involves intense lifestyle changes. This included 1-on-1 training for 6 months, a 7% weight loss, and over 150 minutes per week. We also found that HIIT, resistance training, and low carb diets are also especially effective for preventing diabetes, heart attack, stroke, erectile dysfunction, and dementia.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Weight loss medications have always been notorious for the dangers associated with amphetamine-related medications. But it's a new day. There are new medications related to SSRIs, the newer/safer antidepressants. There's Contrave, which uses a combination of Wellbutrin and Naltrexone. Naltrexone is used for narcotic or alcohol addiction. Orlistat is another medication that blocks digestion of fats.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Diet and exercise are obviously critical to weight loss. But is there a place for medications outside of weight loss clinics? Yes. Overweight and obesity are major (and growing) causes of heart attack, stroke, and cancer.
The easy assumption is that we get fat because we eat too much. But why is there so much weight gain as we get over 50 years old? Understanding this, most of us realize there are endocrine reasons for weight gain. But we often think only of behavior (lifestyle) in relation to treatment of weight gain.
As far as medications are concerned, metformin is usually the best first option for the majority of baby boomers with prediabetes or insulin resistance. Saxenda is simply one of the new diabetes drugs; it's used to be Victoza (liraglutide) but renamed for weight loss. Naltrexone is most often given for alcohol and opiate addiction, but genetics do not favor naltrexone in many patients. However, naltrexone combined with buproprion (Wellbutrin) may be as successful in the form of Contrave.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The Freestyle Libre provides simple, effective, and affordable continuous glucose monitoring (CGM). Its major competition is the Dexcom (like the Dexcom G5). Some current Dexcom users are eligible for a Freestyle at no cost.
What are the differences?
Among other things, Dexcom G5 is constant readout, while Freestyle is readout on request; both are constant read. Freestyle gives a great graph, showing not only the reading but the range by day for all days monitored. The Dexcom G5 is estimated at $3500/year and the Freestyle at $2300/year (Canadian dollars).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Ken Rach, one of PrevMed's followers, is focused on plant-based diet (like many others). He provided a link to Dr. McDougall's lecture to the College of Lifestyle Medicine. I've seen this. I've preached (and lived) the lifestyle gospel for 30 years. After 30 years of plant-based diet, marathons, and a BMI of 21, I developed insulin resistance. I'm not alone. There are other causes of type 2 diabetes, like age and genetics. So what do I tell my patients? Let's discuss plant-based diet & diabetes in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This is a summary of the scientific literature on coenzyme Q10 (CoQ10, ubiquinone) and its reduced form ubiquinol.
It's clear that CoQ10 is safe, important, expensive. That it's a key component of animal cell respiration and drives over 90% of our energy production. It's depleted during disease states, such as heart failure, stroke, and cardiovascular inflammation.
CoQ10 is also depleted by statins. But what's not clear is whether improving levels of CoQ10 actually improve athletic performance and disease outcomes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CoQ10
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
It's amazing how little quality control regulation is done for personal glucometers. As you see on this comparison, you go from an indicator of poor health to good simply by changing the device. How do you make sure you have the right device? In this podcast, let's compare 2 glucometers: Freestyle Lite vs OneTouch Ultra 2.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The debate on cinnamon continues. There is little evidence that it impacts cholesterol or HgA1c. There are several studies indicating that it may improve fasting glucose levels. For prediabetics, it's the post-meal glucose values that are the problem, not fasting glucose values. In addition, the most recent Cochrane meta-analysis did not support any impact at all from cinnamon on any cholesterol or glucose values.
So, why take cinnamon? It's cheap (~$3/month). You might enjoy those occasional cinnamon burps. And maybe it will turn out to help. But if you do take it, you may want to make sure to look for Ceylon, Burmanii, or Cassia cinnamon; these are all really the same thing. Korintje cinnamon is different, although it's not known as there has been far less research on this.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Niacin increases HDL cholesterol, decreases LDL cholesterol, and decreases Lp(a). All meta-analyses agree to this until 2 studies came along—the HPS2 THRIVE and AIM-HIGH. But in an interview. Dr. William Boden (principal investigator of the AIM-HIGH trial) said that the AIM-HIGH trial was misinterpreted and shouldn't be used as a basis to stop niacin therapy.
In this podcast, I'll discuss the details AIM-HIGH trial and why it isn't a basis for abandoning niacin. Here are links to the AIM HIGH article and Dr. Boden's interview:
-
Article: https://www.nejm.org/doi/full/10.1056/nejmoa1107579
-
Interview: https://www.youtube.com/watch?v=iy07edzuvmM
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on niacin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This podcast covers vitamin K2 sources. We contrast that to vitamin K1 sources. We also compare vitamin K2 MK4 to vitamin K2 MK7. Lastly, we'll talk about supplementing vs. getting vitamin K entirely from diet.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin K2
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Tired of hearing that vitamin K2 impacts calcium use in both bone and vessel tissue - without an explanation of how? What's the mechanism? Is it just fabrications and imagination? No. It's real. It involves matrix Gla protein (MGP), osteocalcin, and carboxylation.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on vitamin K2
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Doctors all knew that niacin helps - until the AIM-HIGH study. It was published in the New England Journal of Medicine in 2012. Even though the study author warned against the mistake of over-simplifying to patients' disadvantage, the medical standards groups did it anyway.
Did they "throw the baby out with the bathwater?" What was it about the AIM-HIGH study that confused the issue? too short a time frame? the extended-release component? the statin intervention? How about the safety signal? This video covers these issues and more. -
https://www.nejm.org/doi/full/10.1056/NEJMc1311039
https://www.nejm.org/doi/full/10.1056/NEJMc1311039
If AIM HIGH weren't enough, then HPS2-THRIVE came along, also showing negative results for a niacin trial. Again, this was with a supplement known for decades - and with dozens of studies - to work. What was it this time? Laropripant? Time frame? We also do a brief preview.
https://www.nejm.org/doi/full/10.1056/NEJMoa1300955
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on niacin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Metformin is the well known front-line medication for oral diabetes therapy by the ADA, AACE, etc. But it also has shown weight loss for nondiabetics, including prediabetic, again, PCOS, and mental health patients. Metformin side effects for PCOS and other reasons include gas, diarrhea, occasionally nausea. Supposedly the worst side effect is lactic acidosis, which occurs with the other drugs in the biguanide class.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on metformin & weight loss
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Mitochondria are the powerhouses of the cell. They are critical to health and longevity. As we age, DNA processes begin to fail. These failures can come from damage to DNA or from decreased transcription of genes. These genes make proteins (enzymes) that are critical to cellular respiration, or the process of getting energy out of food. Some of these enzyme names are becoming familiar - AMPK, SIRT1 and the SIRTUINS, p53, and ATM.
Dr. Sreekumaran Nair at Mayo Clinic in Rochester, New York, did a unique study and published his results in March 2017. He had two groups involved; 1 group age 18-30, and another group 65-80. Both groups did HIIT (High Intensity Interval Training) for 3 months. Cardiovascular and lung function improved 28% in the younger group and 17% in the older group.
Here's the unusual part. Muscle biopsies were done, showing actual metabolic, cellular changes in mitochondrial function. The older group had a 69% improvement in mitochondrial function. The younger group had a 49% improvement.
One review of this study stated that HIIT doesn't really make you younger. It went on to say that eating too many doughnuts could overweigh the positive impacts of the HIIT. That seems obvious to me. I think we want to have mitochondria that perform on a healthy level. That is, if we want to be healthy.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I have a viewer that is taking berberine INSTEAD OF METFORMIN. Is that wise?
There is some quality research available suggesting a 2 point drop in HgA1c. There are multiple mechanisms: AMPK-protein kinase activity, improve insulin sensitivity, protect beta cells (pancreatic islet cells), and improve triglycerides (probably due to decreased glucose).
Let's discuss further this topic in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on berberine vs. metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
CT angiogram is an up-and-coming test that's better than stress tests, cardiac catheterization, and stents. Studies, like the PROMISE & SCOT-HEART trials, have shown reduced heart attack incidence among people who took CT angiography.
In this podcast, let's discuss:
- What a CT angiogram is;
- The PROMISE & SCOT-HEART Trials;
- CT angiography vs. stress tests & cardiac cath.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CT angiography
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Researchers at the Karolinska Institute found that a protein called CARD8 is somewhat connected to cardiovascular inflammation. In this podcast, let's have a brief look at CARD8 then have a deep discussion about inflammation and the sure things that drive it.
- What causes cardiovascular inflammation?
- A brief look at CARD8 (Caspase activation and recruitment domain 8);
- What is cardiovascular inflammation?
- The inflammation tests - MACR, myeloperoxidase, Lp-PLA2, C-reactive protein.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on cardiovascular inflammation
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Berberine is one of those supplements used for controlling blood sugar levels. Does it work? How does it fare against metformin?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on berberine vs. metformin
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Arterial plaque regression is a known entity. In this podcast, we go into the details of the process.
- HDL is critical to this process. It pulls the LDL out of the plaque.
- Endothelial cells then repopulate and cover denuded areas, replacing the intima.
- Immune cells (mast cells, monocytes, leukocytes) will actually stop releasing digestive/inflammatory enzymes and cytokines. And, they will regress back away from the area of the previous plaque.
- And of course, the necrotic (dead materials) are cleaned up.
Here's an article which explains the process: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209544.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on cardiovascular inflammation
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
James just tried on a Freestyle Libre continuous glucose monitor (CGM)... and he liked it. In this podcast, we talked about the benefits of using a CGM, how it works, how blood sugar levels changes with sleep, diet, fasting, exercise, and other activities.
- 3 Things James liked about using a CGM;
- Sleep & blood sugar patterns;
- Cortisol & the "dawn effect;"
- "Eat to the glucometer. Live to the glucometer."
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Let's discuss the coronary artery calcium score (calcium score for short), its 4 uses, and what a score means in terms of the degree of a person's cardiovascular risk.
- What is coronary calcium score?
- The 4 uses of calcium score;
- Downsides of calcium scoring;
- Calcium score distribution in men & women;
- Interpreting CV risk using the Agatston calcium score.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on calcium score
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Even though I always maintained a healthy lifestyle, I had challenging genetics. I'm not alone; over half of us have some high-risk versions of 9P21. It's been known as the "cancer" gene and the "heart attack" gene. Now it's clear that it causes both cancer and heart attack due to increased diabetes risk. And there are multiple locations and high prevalence. The bottom line is that most of us have some 9P21 risk. That's why Type 2 Diabetes is so common for people over 50. I have very high 9P21 risk.
However, I made some simple adjustments (5-pound weight loss, increased omega 3s, HIIT training, resistance training, niacin, rosuvastatin, and ramipril). My arterial age dropped steadily over the next 18 months from 73 years old to 52 years old. No matter where I fall in the CIMT/arterial age debate, it's clear I have been lowering my LDL plaque load in my intima-media space.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on my plaque reversal story
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
At a press conference on December 4, 2020, the FLCCC Alliance has called on national health authorities to immediately review medical evidence showing the efficacy of ivermectin for the prevention & early treatment of COVID-19.
In this podcast, let’s discuss:
- The FDA's warning against the ivermectin's use in humans;
- What ivermectin is;
- How ivermectin works against COVID-19;
- The ICON study - how ivermectin benefits hospitalized COVID-19 patients;
- The I-Mask+ (Proposed protocol for preventing & treating COVID with ivermectin).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There's a new drug for Alzheimer's disease that could reverse age-related memory decline. It's called ISRIB (Integrated Stress Response Inhibitor B). What strikes me about this "miracle" drug from UCSF is that its action resembles that of rapamycin.
In this podcast, let's discuss:
- A brief background on rapamycin & autophagy;
- What ISRIB is;
- How ISRIB resembles rapamycin, MTOR;
- ISRIB mechanism & reversal of age-related memory decline.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on cardiovascular inflammation
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Patients may suffer from statin side effects. But according to Dr. James Howard, who presented the SAMSON trial at a 2020 AHA meeting, symptoms are not caused by the statin molecules but by the act of taking a tablet. Moreover, the symptoms are almost as bad as taking a placebo.
In this podcast, let's discuss:
- The SAMSON (N-of-1 clinical trial) and how it was performed;
- Results: atorvastatin (Lipitor) vs. placebo vs. no pills;
- The "nocebo" effect, other explanations and arguments.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on stopping statins
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2 is a related but different chemical from vitamin K1.
Both are fat-soluble.
- K1 is from leafy green vegetable sources, while K2 is from meats, cheeses, eggs.
- K1 is primarily involved in the coagulation process. K2 is involved in bone and vascular tissue calcification.
- While large studies (like the Nurses' Health Study and Health Professionals Follow-Up Study) showed a minimal impact of K2 on cardiovascular health, these studies did not differentiate between K1 and K2.
The Rotterdam Study did show cardiovascular protection with K2 and none with K1. But "protective" in the Rotterdam study means a decrease in the calcification of coronary arteries.
If you have a plaque, it’s better if it’s calcified and not soft. That’s because a calcified or hard plaque is more stable. Significant risk can come from inflaming a soft plaque, forming a deadly clot, and letting that clot cause stroke or a heart attack.
However, the entire story of how K2 affects plaque is not completely understood years ago. Recent research shows that there's more about K2 than just removing calcium from calcified plaques.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
This podcast covers the data and conclusions on the Criqui article in more detail.
Higher CAC (Coronary Artery Calcium) scores lead to a higher risk of heart disease. So, if vitamin K2 pulls the calcium out, it should decrease the risk. Well, it's just not that simple. In fact, the science indicates that increased plaque density and decreased plaque volume are the real indicators.
Let's review the most recent definitive article. To find it, just GOOGLE the following: JACC criqui. Or go to the following link: http://imaging.onlinejacc.org/content/10/8/845.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2's effect on calcium deposition is well-known. But did you know that K2 has other "side effects" that seem unrelated to calcification? In medicine, we called such "side effects" as pleiotropic effects or pleiotropic roles.
In this podcast, I'll describe what the pleiotropic effect is by using antihistamines, Marfan syndrome gene, Alzheimer's, and statins as examples. In the end, you'll find out that vitamin K2 not only impacts calcification but also impacts IR (insulin resistance or prediabetes) and inflammation.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
A viewer Shane Creamer alerted me to the following great article in Nutrient magazine in 2015 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586551).
This was an excellent study looking at the science behind the effect of olive oil on CV inflammation. The Cochrane clinical trial meta-analysis processes were used well. There were 30 studies that met the criteria. These included a total of 3106 participants.
Olive oil showed improvement in C-reactive protein, flow-mediated dilation, and interleukin 6. There are differences between things such as supplementation vs. diet. There was some comparison to other oils, but these comparisons were not so clear in terms of the study write-up.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CV inflammation
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The movie "What The Health" is getting a lot of air time recently. It basically preaches the plant-based diet approach for 30 years.
But it's not that simple. Orange juice and grape juice are just like taking an oral glucose tolerance test. It is a major stressor to the beta cells of the pancreas.
Others (like Robert Lustig) would say that these sugars are the real problem. He, like Gary Taubes in "Why We Get Fat," is talking about the hormonal theory of weight gain.
In short, eating sugars raises insulin. Insulin, in turn, stops fat burning. It also results in ghrelin ( the hunger hormone) release. So there's still debate about whether eating fat or sugar makes you fat. But there's no debate for diabetics. Sugar is bad for them.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Red yeast rice has been used for centuries in Chinese medicine. It has been shown to decrease cholesterol. It includes HMG-CoA reductase materials. In fact, statins were originally developed from Monacolins, the fungus used to make red yeast rice.
The FDA declared Monacolin products as a drug and tried to stop the sale of supplements containing it. This decision went to court and was overturned by the US Court of Appeals. They actually typically contain 10-20 mg of monacolins. Mevachor, made by Merck from red yeast rice, contains 20-80 mg of monacolins. So you're taking the same thing but usually at a lower dose. Side effects are the same: liver function problems, muscle breakdown.
I prefer to use better statins at far lower doses. And I don't appreciate the patent formula product salesmen all over the web saying, "my product, XXX, is safer, more effective, and contains the exact right combination..... blah, blah, blah."
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In the early days of the COVID-19 pandemic, doctors noticed something about people who became severely ill—Many were obese.
In this podcast, let's talk about:
- The obesity and COVID-19 link (heart disease, diabetes, ACE2 receptor, leptin resistance, inflammation);
- Complications of hospital care for obese patients;
- What can be done with obesity and COVID-19.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
CoQ10 stands for coenzyme Q10. It is used for ATP, which is in turn critical to cell respiration which provides over 90% of human cell energy.
Ubiquinol is the reduced alcohol form of CoQ10. It's supposed to be the most effective and easily absorbed form. On the other hand, ubiquinone is the oxidized ketone form.
Statins are HMG-CoA reductase inhibitors. When they stop cholesterol production, they also decrease CoQ10 production.
There is a lot of great research on ubiquinone & ubiquinol. However, the study results conflict. There seems to be evidence that we can elevate our levels of CoQ10. But it's not so clear that it works. Part of the evidence is that it's difficult to assume an improvement in biological status based on mitochondrial improvement. That in turn requires assumptions that lung, heart, and vascular functions are not the actual rate-limiting problem.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on CoQ10
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There's a new drug for Alzheimer's disease that could reverse age-related memory decline. It's called ISRIB (Integrated Stress Response Inhibitor B). What strikes me about this "miracle" drug from UCSF is that its action resembles that of rapamycin.
In this podcast, let's discuss:
- A brief background on rapamycin & autophagy;
- What is ISRIB?
- How ISRIB resembles rapamycin, MTOR;
- ISRIB's mechanism & reversal of age-related memory decline.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Using BMI to predict heart disease risk has problems. DEXA scan & RFM are more accurate, but they still can't unseat BMI.
There's a new contender—using AI to analyze CT images of the belly or gut, which proves to be a better predictor of heart attack & stroke.
In this podcast, let's discuss:
- The problem with BMI (body mass index);
- The fact that body fat is not just a storage tissue;
- AI analysis of abdominal CT imaging ((https://www.sciencedaily.com/releases/2020/12/201202114507.htm);
- How AI/machine learning helps predict heart attack & stroke;
- BMI vs. DEXA scan vs. RFM (relative fat mass).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
One way to reduce or reverse arterial plaque is to improve one's blood glucose numbers. Can anti-diabetes medications metformin & pioglitazone help in this area?
In this podcast, let's discuss:
- Ways to reverse arterial plaque;
- How metformin works;
- How pioglitazone works.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on arterial plaque reversal
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There is no question that diet is the most important part of preventing heart attack, stroke, and other common forms of death & disability (such as Alzheimer's).
But as an experienced & credentialed prevention physician, I think there is "more heat than light" on the diet debates. "More heat than light" means there is a lot of emotion, but not so much illumination.
I know the science. But it's not really a science thing, either. It a beliefs thing. There are beliefs, perceptions, and habits that create a major problem for the majority of us to know how to develop a healthy diet. We, therefore, create major risk for ourselves almost every time we eat - yet we don't know it.
This is not a science review, but I do mention a couple of articles. This is the Hayashi article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631850/pdf/1229.pdf
And the following article deals with awareness of post-prandial insulin: https://openheart.bmj.com/content/openhrt/4/2/e000656.full.pdf
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I have a patient whose calcium score keeps increasing despite a keto diet, chelation therapy, and supplements. Then we found out that he had unrecognized diabetes. His wife was thankful we discovered the problem.
In this podcast, let's discuss why this patient's calcium score keeps increasing, and the connection between calcium score & unrecognized prediabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's article on prediabetes
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The path of stress test-cath lab-stents is something I would call the "unholy triumvirate."
Why? Because one thing leads to another, and in the end, they all lead to a false sense of security on the patient's part.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's stress test article
- PrevMed's stress test-cardiac cath-stent article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2 impacts calcium use in both bone and blood vessel tissues, but there's not much explanation of how that happens. That mechanism is now explained with matrix Gla protein (MGP), osteocalcin, and carboxylation.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Higher calcium scores on CACS (Coronary Artery Calcium Score) is believed to mean a higher risk for cardiovascular events (heart attack or stroke). So the web is full of advice on removing calcium from plaque using vitamin K2.
Is that assumption correct? Is it really safe to remove calcium from plaque?
There have been studies showing that inflamed/liquid/"hot" plaque is unstable, not the type of plaque that's hardened with calcium. In fact, many believe that calcium is like a mortar, adding strength to the plaque.
There is evidence from the MESA study (published by Criqui et al. in JACC in October 2017) supporting this. In fact, the point of this study was that increasing calcium density was "cardioprotective."
This explains what we've seen for years: a higher volume of calcium means many cycles of inflammation and laying down of plaque have already happened. However, increased density of calcium is cardioprotective; it indicates that plaque is stable and inflammation has decreased.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
If you then have a positive stress test, you’ll likely be led to the catheter lab for a coronary angiogram. If plaque is detected, you’ll then be recommended to have a coronary stent. This progression—from stress test to cardiac catheterization to stent—is tragically a common (yet often unnecessary) triad of cardiology procedures.
In this podcast, let's discuss:
- Cardiac stress tests, cardiac cath & stents - common but unnecessary procedures;
- What is cardiac catheterization? Coronary angiography? Coronary stents?
- COURAGE, ORBITA, & ISCHEMIA trials;
- Risks & downsides;
- Are stress tests, cardiac cath, & stents unnecessary & overused?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's stress test article
- PrevMed's stress test-cardiac cath-stent article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Rosuvastatin (Crestor) has a half-life of 17 hours. That means it takes 17 hours for half of the medication to be excreted/neutralized/metabolized. So that allows us to give Crestor every other day, or even 3 times per week.
Very low doses of rosuvastatin have a positive impact on inflammation. We routinely give 5 or even 2.5 mg. If the inflammatory markers are low, and there are no unusual cholesterol problems, we can even go to 3 times per week dosage. Brad Bale and Amy Doneen have even reported decreases in inflammation from having some intolerant patients "lick" the tablet 3 times/week.
Yes, lower doses are good. And they mean lower side effects.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's statin article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Osteoarthritis (OA) & cardiovascular disease (CVD) are 2 of the most prevalent conditions affecting the US population. Although OA is the most common arthritis, we know very little about the relationship between OA and CVD. One study published in BMJ Open, however, sought to describe the connection between the 2 conditions.
- What is osteoarthritis?
- 4 reasons why OA may be associated with CVD;
- A 2013 study that described the correlation between OA & CVD (https://bmjopen.bmj.com/content/3/5/e002624).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Metformin is a popular anti-diabetes medication. But it is also said to be an anti-aging drug.
This podcast is based on David Sinclair's new book, "Lifespan: Why We Age and Why We Don't Have To." Here, we'll talk about metformin, metformin's benefits, multiple metabolic pathways impacted by metformin, and the TAME study (Targeting Aging with Metformin).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's metformin article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Which statins are best for cardiovascular Inflammation? And how do statins actually impact cardiovascular inflammation? I know Lipitor (atorvastatin) works, but not as well as Livalo (pitavastatin), Crestor (rosuvastatin), pravastatin, or simvastatin. However, Livalo is prohibitively expensive, while Crestor has lost its patent for years now so it's not expensive.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's statin article
- PrevMed's cardiovascular inflammation article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The vast majority of heart attack and stroke is not caused by full-blown diabetes but prediabetes. In this podcast, let's cover some quick facts about prediabetes, the types of tests, and how to manage such conditions.
- Prediabetes or type 2 diabetes?
- Why hemoglobin A1c test is not reliable;
- Oral glucose tolerance test (OGTT) vs. fasting blood sugar (FBS);
- The optimum insulin numbers;
- How to manage prediabetes/diabetes;
- How diet (e.g. low-carb, carnivore) affects your glucose metabolism.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's prediabetes article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Stress tests are the go-to measurement for arterial plaque. Its supposed goal is to predict a heart attack. Unfortunately and ironically, stress tests don’t measure plaque—they only measure blood flow.
In this podcast, let’s describe:
- Cardiac stress test & its types (stress ECG, stress echo, nuclear stress testing);
- What a stress test can tell you;
- Why a stress test can't reliably predict a heart attack;
- How accurate are stress tests.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's stress test article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The ankle-brachial index (ABI) test is a quick, DIY way to measure arterial plaque and whether you have peripheral artery disease. You can do it at home, but care must be taken when interpreting results.
In this podcast, let's discuss:
- How to perform the ankle-brachial index test
- What to consider when interpreting ABI test results
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In this podcast, let's discuss what we know so far about the 3 early COVID-19 vaccines that were approved/to be approved by the US FDA as of Dec. 2020: Moderna, Pfizer-BioNTech, and Oxford-AstraZeneca vaccines.
- How are Pfizer-BioNTech, Moderna, & Oxford-AstraZeneca vaccines made;
- How are COVID-19 vaccines approved;
- How are the COVD-19 vaccines handled;
- What is herd immunity?
- Who gets vaccinated first;
- The 2-dose vaccination process;
- Can people choose their COVID-19 vaccine?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There has been significant buzz about bergamot, the essential oil found in flavoring Earl Gray tea. The impact comes from a couple of chemicals in the flavonoid class found in higher concentrations than in any other fruit. These flavonoids have a similar impact with the chemical found in red rice yeast and statins; it decreases cholesterol production. It has also been shown to decrease blood sugar. But the information is not so clear yet in this area.
Can bergamot replace statins? Is bergamot a lot safer than metformin? In this podcast, we'll answer such questions.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I provide a lot of cutting-edge science regarding cardiovascular risk. But cutting-edge research is, by nature, rarely conclusive. So I get a lot of viewer requests to provide easier, simpler rules regarding cardiovascular health. Here are 15 of them.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's cardiovascular inflammation post
- PrevMed's prediabetes post
- PrevMed's arterial plaque post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin D, vitamin K2, niacin, bergamot, and berberine are some supplements with reported cardiovascular (CV) benefits.
- Vitamin D is essential for healthy bones; supports the brain, immune and nervous systems; regulates insulin levels; and promotes CV health. Target vitamin D level in the blood should be between 60-80 ng/mL. Persons with < 30 ng/ml were up to 5x at greater risk for developing diabetes than people with > 50 ng/ml. However, too high doses can have toxic side effects.
- Vitamin K2 affects bone growth/loss. Studies have shown that it also has a preventive impact on prediabetes.
- Niacin is recommended for patients with significant Lp(a) and for increasing HDL.
- There is medical evidence that bergamot extract positively impacts blood glucose & cholesterol levels. Like statins, bergamot oil has the same impact on the enzyme that creates cholesterol HMG synthetics. It also has been shown to have anti-inflammatory & antioxidant effects, and it may improve LDL, HDL, and several other things.
- Traditional Chinese herb extract berberine drops HbA1c by 2 points, which is the same as metformin. It might be a good alternative for treating type 2 diabetes, hyperlipidemia, and hypertension over a long-time period.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin D post
- PrevMed's vitamin K2 post
- PrevMed's niacin post
- PrevMed's berberine post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
A viewer asked whether vitamin K2 is a reasonable tactic for arterial plaque reduction, and if yes, how much vitamin K2 should be taken.
I tackled those topics in this podcast. I also mentioned vitamin K2's connection with insulin resistance and enzymes like MGP (matrix Gla protein) and osteocalcin.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In this podcast, I tackled vitamin K's relationship with a calcium-binding protein called "matrix Gla protein" (MGP).
According to a 2015 article that was published in JACC (Journal of the American College of Cardiology):
- MGP pulls out calcium from blood vessel walls. Therefore, MGP's activity prevents vascular calcification, arterial damage, and decline in renal function.
- Vitamin K's role is to activate MGP.
- However, warfarin and other "vitamin K antagonists" prevent vitamin K from activating MGP. In other words, warfarin and vitamin K antagonists indirectly block MGP from doing its activity.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2 may have more promise than I originally thought.
I just read the book "Vitamin K2 and the Calcium Paradox" by Kate Rheaume-Bleue. The book brings up some interesting concepts about vitamin K2 which I was unaware of. Examples include osteocalcin, which appears to have a role both in calcium deposition and glucose metabolism.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Niacin (vitamin B3) is touted as one of the natural ways to raise HDL levels. But does it really work? And how much should you take for niacin to be effective?
In this podcast, let's talk about:
- Ways to increase HDL levels;
- Does niacin work?
- No flush niacin;
- The recommended niacin dosage.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There appears to be an overlap between the risks of insulin resistance and Alzheimer's disease, dementia, cognitive decline.
In this podcast, let's talk about:
- My brief encounter with Dr. Dale Bredesen (author of the book "The End Of Alzheimer's");
- Brain insulin and memory loss;
- The unrecognized prediabetes epidemic.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's post on "The End of Alzheimer's"
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Many people focused more on LDL cholesterol as being the cause of heart attacks and strokes. While plaque consists of oxidized LDL cholesterol, having a high LDL level isn’t the problem. Recent studies showed that it’s actually inflammation that is the culprit here.
In this podcast, let's discuss:
- Inflammation and heart disease;
- How cardiovascular inflammation leads to heart attack and stroke;
- How to test & detect cardiovascular inflammation (CRP, MACR, Lp-PLA2, myeloperoxidase, IL-6);
- Prediabetes and cardiovascular inflammation;
- Can we delay atherosclerosis & cardiovascular inflammation?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's inflammation post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Blood clots are dangerous. They could cause a heart attack or stroke. Inflammation is a leading cause of such blood clots, while prediabetes can lead to inflammation.
In this podcast, let's discuss:
- Why doctors miss prediabetes in patients;
- The connection between inflammation & prediabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's inflammation post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
An increase in coronary calcium score worries many people. But a high calcium score could mean lots of things. In some cases, it indicates the presence of stable plaques, which is a good thing.
In this podcast, let's discuss:
- What a high calcium score is;
- Soft plaque vs. hard plaque;
- Can we reverse a high calcium score?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The FDA announced another recall of metformin ER on October 5, 2020. Since December 2019, the FDA has been investigating the presence of NDMA (a possible carcinogen) in some metformin batches. Does this mean patients should stop taking metformin as their diabetes medication?
In this podcast, let's discuss:
- The FDA metformin recalls
- Why is metformin being recalled?
- NDMA (the contaminant in recalled metformin batches, ARBs, & other meds)
- Should we stop taking metformin?
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
An old running friend of mine used to say, "it isn't that 'diabetes runs in the family.' It's that nobody in the family runs."
Sounds like a great quip. But here's the truth: running helps, but it isn't complete protection. Get checked!
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blogs
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Inflammation causes heart attacks and strokes. However, the inflammation process isn't easy to visualize. But when you see how an inflammation looks on the outside (say, in the skin), you'll understand how inflammation impacts the arteries.
In this podcast, let's talk about:
- What inflammation looks like on the outside;
- My story with imiquimod & cytokines;
- What inflammation does to our arteries (injured glycocalyx, cardiovascular inflammation);
- The various Inflammation markers and tests.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's inflammation post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Does vitamin K2 move calcium out of stable, calcified plaque? Or does vitamin K2 improve insulin sensitivity?
In this podcast, let's discuss:
- A brief history and background of vitamin K;
- The difference between vitamins K1 and K2;
- Vitamin K2 and calcification;
- Vitamin K2 and diabetes, prediabetes, insulin resistance.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There's still caution in taking vitamin K2 with the belief that vitamin K2 takes calcium out of stable, calcified plaques. In this podcast, let's clarify vitamin K2's role in the calcification/decalcification process, and whether decalcification of arteries really increases a person's cardiovascular risk.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There was a lot of information that came out on the topic of vitamin D and COVID-19.
In this podcast, let's talk about:
- Vitamin D and its health benefits;
- How vitamin D acts against respiratory tract infection;
- How vitamin D lowers inflammation & suppresses cytokine storm;
- The relationship between vitamin D deficiency & COVID-19 mortality;
- Vitamin D sources (e.g., sunlight, diet, supplements);
- The safe dosage of vitamin D.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin D post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Triglycerides (TG) and HDL are critical to our health, so knowing them should suit us well.
In this podcast, let's talk more about:
- The TG/HDL ratio, how to calculate it, its importance, and the optimal range;
- TG/HDL ratio variation by ethnicity;
- How to lower triglycerides and increase HDL (naturally & through medications);
- How lowering carbs affects TG/HDL ratio, remnant cholesterol, & cardiovascular risk;
- The connection between triglycerides and diabetes/prediabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Triglycerides and HDL are critical to our health, so knowing them should suit us well.
In this podcast, let's discuss:
- Drs. Attia & Dayspring's discussion about lipids & TG/HDL ratio;
- What a triglyceride (TG) is;
- What high-density lipoprotein (HDL) is;
- The connection between prediabetes & TG;
- How TG affects HDL & LDL;
- What remnant cholesterol is.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The common question about vitamin K2 is whether it could destabilize already stable, calcified plaques. In this podcast, I addressed that question. I also shared:
- Where I get my supply of vitamin K2.
- Whether vitamin K2 is risky for people who got stents or had a CV event.
- Vitamin K2 supplements, natto, & dosage.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin K2 post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
I had a recent talk with an old friend. His name is Charles, and we know him on this channel as OAG (Old Alabama Gardener). He shared his recent CIMT result. And one good thing is that his arterial age is now younger than his actual age by 17 years!
In this podcast, we'll talk about:
- The CIMT test vs. calcium score
- How to use the nomogram of CIMT
- Soft vs. heterogeneous vs. hard/calcified plaques
- What OAG did to get such good CIMT results
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There are many ways used to detect and measure plaque—stress tests, Agatston score through a calcium CT scan, CIMT, and angiograms. But all these tests may come at a cost, and you need to visit the clinic or laboratory to get them done.
There is one DIY test which you can easily do at home—the ABI or Ankle Brachial Index. You can perform it with just your BP (blood pressure) monitoring tool. In this podcast, I’ll explain what ABI is, how to do ABI test, how to calculate and interpret your ABI results, and ABI's limitations.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin D, vitamin K2, niacin, bergamot, and berberine are some supplements with reported cardiovascular (CV) benefits.
- Vitamin D is essential for healthy bones; supports the brain, immune and nervous systems; regulates insulin levels; and promotes CV health. Target vitamin D level in the blood should be between 60-80 ng/mL. Persons with < 30 ng/ml were up to 5x at greater risk for developing diabetes than people with > 50 ng/ml. However, too high doses can have toxic side effects.
- Vitamin K2 affects bone growth/loss. Studies have shown that it also has a preventive impact on prediabetes.
- Niacin is recommended for patients with significant Lp(a) and for increasing HDL.
- There is medical evidence that bergamot extract positively impacts blood glucose & cholesterol levels. Like statins, bergamot oil has the same impact on the enzyme that creates cholesterol HMG synthetics. It also has been shown to have anti-inflammatory & antioxidant effects, and it may improve LDL, HDL, and several other things.
- Traditional Chines herb extract berberine drops HbA1c by 2 points, which is the same as metformin. It might be a good alternative for treating type 2 diabetes, hyperlipidemia, and hypertension over a long-time period.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's vitamin D post
- PrevMed's vitamin K2 post
- PrevMed's niacin post
- PrevMed's berberine post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
When it comes to a healthy lifestyle, Dr. Ford Brewer was your typical poster boy.
He started his career as an ER doctor in his early 20s. He went to John Hopkins to study preventive medicine. He loved it, and he did well. He practiced a good lifestyle, performed regular exercises, and observed a plant-based diet.
All these things, however, didn’t ensure crystal-clear arteries for him. In February 2015, Dr. Brewer went through a CIMT test, and he got a surprise—he got plaques here and there, in different parts of his body. He was 57 then, but his arterial age is roughly 73 years old!
So he had a lifestyle check and realized some things. He then followed the standard practices to address his plaque. He changed several aspects of his lifestyle to reverse 20 years’ worth of arterial plaque.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In this podcast, Dr. Ford Brewer went over a Harvard Health Letter article titled "Can we reduce vascular plaque buildup?" He pointed out:
- what information he agrees and disagrees with in terms of inflammation and cardiovascular disease;
- what causes arterial plaque;
- how to reverse arterial plaque buildup—statins, other medications, and lifestyle changes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Gerry had a stent at the age of 71 despite tracking his markers since he was 35 and following the "standard of care."
Now, he is using 4 tracking trails: lipids, glucose, inflammation, and imaging (CIMT test, calcium score, and CT angiogram). He also went through a change of diet, statins, and supplements.
Let's hear about Gerry's education and lifestyle journey in this podcast.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
John Lorscheider was a frequent contributor and moderator of our forum and YouTube channel. He was also a PrevMed patient. Like most of us, John’s family and personal history include significant cardiovascular risk.
In this podcast, listen:
- a bit about John's background;
- about John's inflammation and carotid IMT test results;
- how OGTT and insulin survey helped John discovered that he was borderline diabetic;
- how John used calcium scan to track his plaque growth/regression;
- about the several changes John implemented (medications, supplements, diet, exercises) to successfully lower his calcium score by 59% within 16 months.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Niacin increases HDL cholesterol, decreases LDL cholesterol, and decreases Lp(a). All meta-analyses agree to the power of niacin until 2 studies came along—the HPS2-THRIVE and AIM-HIGH.
But in an interview, Dr. William Boden (principal investigator of the AIM-HIGH trial) said that the AIM-HIGH trial was misinterpreted and shouldn't be used as a basis to stop niacin therapy.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Consuming saturated fats—is it healthy? Answering this question is not that simple, with several studies showing conflicting findings.
Let's discuss some of those studies, the book "The Big Fat Surprise" by Nina Teicholz, and a recent state-of-the-art review published in JACC.
Materials for this podcast were taken from the following links:
- Saturated Fat and CAD: It's Complicated
- Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions
- Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations - JACC State-of-the-Art Review
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Coconut oil has been a part of the dietary fat battle for decades.
- Coconut oil is saturated fat. Therefore, it has been thought to be a problem, causing weight gain and heart disease.
- On June 18, 2017, the AHA (American Heart Association) published a "Presidential Advisory" on dietary fats and heart disease. In that study, the body stated unequivocally that it does not recommend coconut for heart disease.
- Bruce Fife wrote a book called, "The Coconut Oil Miracle." Is this really true? Probably not. Others would still call coconut a villain. That's probably not true, either.
- But coconut oil also is made up of MCTs (medium-chain triglycerides). Recent studies say that not only are MCTs not bad; they are actually good for you. There is some evidence to indicate this may be true.
At this point, things about coconut oil remain inconclusive.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
HDL is the major healthy way of removing plaque from artery walls. For instance, if your LDL is all the way up at 220 mg/dL, you can still have less heart attack and stroke risk than someone at an LDL of 100 mg/dL. How? By having a high HDL level, say, 65 mg/dL. As you see, HDL is very cardio-protective.
Autophagy comes from the roots "auto" (meaning self) and "phage" (meaning to eat). Autophagy is an important process that happens on the cellular level. It is a major contributor to health. If you're obese, you're not giving your body much chance to use autophagy.
Inflammation is another way the body attempts to get plaques out of the artery wall. Unfortunately, it is the most common cause of heart attack, stroke, and dementia. Inflammatory cells release enzymes, which digest and liquefy plaque. This liquified (or inflamed) plaque can cause clot if it gets into the bloodstream. These clots could cause of heart attack and stroke.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2's effect on calcium deposition is well known. But did you know that K2 has other "side effects" that seem unrelated to calcification? In medicine, we called such "side effects" as pleiotropic effects or pleiotropic roles?
First, let's describe what the pleiotropic effect is by using antihistamines, the Marfan syndrome gene, Alzheimer's, and statins as examples. Then we'll cover that vitamin K2 not only impacts calcification but also impacts IR (insulin resistance or prediabetes) and inflammation.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Niacin is vitamin B3. It was originally called the "PP" factor (pellagra prevention factor). It is involved in many metabolic processes and has been found to have a positive impact on cholesterol, lipid, and cardiovascular problems than any medicine or supplement.
However, 2 studies—the HPS2-THRIVE and AIM HIGH—started a new debate on whether niacin is truly effective.
- The problem with HPS2-THRIVE was laropiprant. Laropiprant is a popular medication used to stop niacin flush (a common side effect to taking niacin). But laropiprant appears to stop not only the flush but also the positive impacts of niacin.
- AIM HIGH was another study that failed to show the positive impacts of niacin. There is a lot of debate regarding why. It ranges from the thought of niacin not working to problems with the AIM-HIGH's design.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
David Sinclair, Ph.D., a tenured faculty at Harvard, is one of the top anti-aging researchers in the world. He is renowned for his work on resveratrol, sirtuins, and NMN.
Resveratrol is a chemical found in red wine. It stimulates certain sirtuins, a family of proteins that have been shown to regulate lifespan, oxidative stress, and DNA damages. Thus, resveratrol appears to have anti-aging benefits, but one has to drink lots of glasses of red wine to get enough resveratrol.
Dr. Sinclair's team then discovered an analog of resveratrol called NMN (nicotinamide mononucleotide). NMN is a precursor/booster of NAD, another key component of the animal cell's respiration, or metabolism.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Nitric oxide (NO), a colorless gas, has been discovered and used for decades. In 1998, the Nobel Prize for Medicine went to Drs. Furchgott, Murad, and Ignarro for their discoveries leading to understanding NO.
Inside the body, NO can relax the smooth muscles like that of the arteries. For instance, nitrates and nitrites have been used to decrease angina. Relaxing the smooth muscles of the veins and arteries decreases the load on the heart. That's how it decreases the pain of angina.
This effect of NO also makes NO useful against high blood pressure and erectile dysfunction.
L-arginine and citrulline are metabolic precursors of NO. In this podcast, we'll cover some studies dealing with L-arginine and citrulline as supplements.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Nitric oxide (NO) is essential for the health of the artery. So anything that boosts NO levels can have a huge impact on cardiovascular health.
Citrulline is converted by the kidneys to L-arginine and then to nitric oxide (NO). It is used for many things: erectile dysfunction, bodybuilding, cycling, and other athletic activities, high blood pressure or hypertension, and even diabetes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Berberine is one of those supplements used to control blood sugar levels. This is the same area where metformin is known for. With some people who don't like taking metformin, berberine can be an alternative. In this podcast, let's discuss if berberine is as potent as metformin.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Statins are primarily known as an LDL cholesterol-lowering medication. But statins (even in low doses) can decrease cardiovascular inflammation. Some statins also help regulate insulin resistance. All these combined effects make a low dose statin a good component of a patient's regimen for reducing cardiovascular plaque.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
An article titled "Can we reduce vascular plaque buildup?" was posted in Harvard Health. In this podcast, let's discuss that article in terms of inflammation and cardiovascular disease, what causes arterial plaque, how to reverse arterial plaque buildup, and statins and lifestyle changes.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
In this podcast, we will talk about weight loss, and Dave Murphy agreed to tell his story.
Dave tried fad diets but couldn't keep the weight off. He got a high calcium score. He's almost ready for bypass until he looked into intermittent fasting and keto. Dave's story just shows that lifestyle improvements make a bigger difference than any medication, supplement, or surgery can do for long-term health.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
The book "The Big Fat Surprise" by Nina Teicholz is highly acclaimed for debunking several myths surrounding saturated fats. In this podcast, we'll cover Teicholz's book and a recent JACC article which also looked into the saturated dietary fat issue.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There have been many studies on populations that stop statins. There are several things to consider. One is the reason for starting statins. Another is the stability of the patient. This podcast goes into stopping statins for stable patients.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Juice Plus has a great product concept. Juice fruits and vegetables, take the carbs out, add vitamins and other nutrients. Bear Grylls, the German Olympic team, and OJ Simpson (the Juice) have all endorsed it.
However, Juice Plus has been criticized by research groups and shut down by multiple state and federal regulators.
Dr. Ford Brewer thinks there's a potential for Juice Plus' concept—getting your fruits and veggies without all the carbs, and not having to eat all those carbs. He tried it but not sure whether to continue it.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Higher CAC (coronary artery calcium) scores could indicate a higher risk for cardiovascular events. And the Internet is full of advice on removing calcium from plaque through vitamin K2. Is that assumption correct? Is it really safe to remove the calcium from plaque?
There have been studies showing that soft, inflamed, or "hot" plaque is the kind of plaque that is unstable, not calcified or hard plaque. In fact, many believe that calcium adds strength and stability to plaque. This is supported by the MESA study, published in JACC in October 2017.
The point of the MESA study: increasing calcium density provides a protective effect. Yes, increasing coronary calcium volume increased the risk of a cardiovascular event, but the increased density of calcium was cardioprotective.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Serrapeptase is a proteolytic enzyme produced by bacteria in the gut of a silkworm. It is used by the silkworm to dissolve the cocoon. It's hailed as a natural anti-inflammatory, with lots of promise and with no side effects. It is also claimed to have an effect against the build-up of cardiovascular plaque.
But does serrapeptase work?
If you go to sources like LEI (Life Extension Institute), you get a great story about the "huge potential" and "no reported side effects" of serrapeptase. But if you go to harder science sources (like ClinicalTrials.gov, Cochrane Library, PubMed, Medline), you would get a different story.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Metformin is a well-known front-line medication for oral diabetes therapy by the ADA, AACE, and other organizations. But it also has shown other beneficial effects against:
- weight problems for non-diabetics and prediabetics;
- against PCOS (polycystic ovary syndrome);
- mental health problems;
- senility and aging-associated conditions;
- cancer.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Can mouthwash cause erectile dysfunction (ED)? What does that have to do with nitric oxide (NO)?
In this podcast, Dr. Ford Brewer and Dr. Doug Thompson (Wellness Dentistry Network) discussed NO, its health benefits, its connection to cardiovascular health, ED, and periodontal health, and whether it's a good idea to take NO supplements (like citrulline and L-arginine).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Vitamin K2 is a related but different chemical from vitamin K1.
- Both are fat-soluble.
- K1 is from leafy green vegetable sources, while K2 is from meats, cheeses, eggs.
- K1 is primarily involved in the coagulation process. K2 is involved in bone and vascular tissue calcification.
While large studies (like the Nurses' Health Study and Health Professionals Follow-Up Study) showed a minimal impact of K2 on cardiovascular health, these studies did not differentiate between K1 and K2.
The Rotterdam Study did show cardiovascular protection with K2 and none with K1. But "protective" in the Rotterdam study means a decrease in the calcification of coronary arteries.
If you have a plaque, it’s better if it’s calcified and not soft. That’s because a calcified or hard plaque is more stable. Significant risk can come from inflaming a soft plaque, forming a deadly clot, and letting that clot cause stroke or a heart attack.
However, the entire story of how K2 affects plaque is not completely understood years ago. Recent research shows that there's more about K2 than just removing calcium from calcified plaques.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog post
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Metformin is a well-known front-line medication for oral diabetes therapy by the ADA, AACE, and other organizations. But it also has shown other beneficial effects against:
- weight problems for non-diabetics and prediabetics;
- against PCOS (polycystic ovary syndrome);
- mental health problems;
- senility and aging-associated conditions;
- cancer.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Even though Dr. Ford Brewer always maintained a healthy lifestyle, he had challenging genetics. He's not alone, though. Over half of us have some high-risk versions of the 9P21 gene, the "cancer" and the "heart attack" gene. That's why type 2 diabetes is so common for people over 50 years of age.
He made some simple adjustments (e.g., 5-pound weight loss, increased intake of omega 3s, HIIT and resistance training, niacin, rosuvastatin, and ramipril). His arterial age dropped steadily over the next 18 months, from 73 years old to 52 years old.
So no matter where you fall in the CIMT/arterial age debate, take comfort in the thought that Dr. Brewer lowered the plaque load in his intima-media space.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Metformin is a popular anti-diabetes medication. But it is also hailed as an anti-aging drug too.
This podcast is based on David Sinclair's new book, "Lifespan: Why We Age and Why We Don't Have To." We'll talk about metformin, metformin's benefits, multiple metabolic pathways impacted by metformin, and the TAME study (Targeting Aging with Metformin).
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There have been many studies on populations that stop statins. There are several things to consider. One is the reason for starting statins. Another is the stability of the patient. This podcast goes into stopping statins for stable patients.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
Most docs and patients ignore the important warnings of having an elevated TG/HDL ratio.
In this podcast, let's:
- review the cholesterol panel;
- explain HDL and LDL. (They are basically the same, except the LDL is more full and carries more cholesterol and triglycerides.
- connect high blood glucose, insulin levels, triglycerides, HDL, LDL, and inflammation.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page
There have been many studies on populations that stop statins. There are several things to consider. One is the reason for starting statins. Another is the stability of the patient. This podcast goes into stopping statins for stable patients.
For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:
- PrevMed's blog article
- PrevMed's website
- PrevMed's YouTube channel
- PrevMed's Facebook page