Podcast – GI_Pearls: Recent Episodes

Dmitriy Kedrin

Gastroenterology Literature Review

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Show Notes for Episode 63 of GI Pearls

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Episode 62 Show Notes July 2023

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Episode 61 Show Notes June 2023

  1. Efficacy of a Second PPI Course After Steroid-induced remission in EOE refractory to initial PPI therapy. – ACG
  2. AGA Clinical Practice Update on Management of Subepithelial Lesions encountered during routine Endoscopy: Expert Review – CGH
  3. Prune juice Containing Sorbitol, Pectin and Polyphenol Ameliorates subjective complaints and Hard Feces while Normalizing Stool in Chronic constipation: A randomized placebo-controlleD Trial. – Am J Gastro
  4. Adenoma Detection Rate and Risk for Interval Post colonoscopy Colorectal Cancer in Fecal Immunochemical Test–Based Screening – Annals of IM
  5. Latiglutenase Protects the mucosa and attenuates symptom severity in patients with celiac disease exposed to a gluten challenge – Gastro
  6. Evaluation of real-time computer-aided polyp detection system during screening colonoscopy: AI-DETECT study – Endoscopy

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Show Notes for GI Pearls Episode 60 What is the Prevalence of Clinically Significant Endoscopic Findings in Subjects With Dyspepsia? Updated Systematic Review and Meta-analysis – CGH Quality of upper GI endoscopy: a prospective cohort study on impact of endoscopist education – GIE Association between endoscopist specialty and colonoscopy quality: a systematic Review and meta-analysis.… Continue reading GI Pearls Episode 60

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Show notes for Episode 59 GI Pearls Podcast Cannabidiol for Functional Dyspepsia With Normal Gastric Emptying: a RCT. – Am J Gastro Randomized Controlled Trial Investigating Cold Snare and Forceps Polypectomy among small POLYPs in Rates of Complete Resection: The TINYPOLYP Trial – Am J Gastro Vonoprazan triple and dual therapy for Hpylori infection in… Continue reading GI Pearls Episode 59 Short

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Episode 58 Show notes Cold versus hot snare resection with or without submucosal injection of 6-15mm colorectal polyps: RCT. – GIE Prospective cohort study to investigate the safety of preoperative tumor necrosis factor inhibitor exposure in patients with inflammatory bowel disease undergoing intra-abdominal surgery.  – Gastroenterology Clip Closure does not reduce risk of bleeding after… Continue reading GI Pearls Episode 58 Short

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Articles discussed Clinically significant serrated polyp detection rates and risk for postcolonoscopy colorectal cancer: data from the New Hampshire Colonoscopy Registry – GIE Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice. – GIE Fecal Microbiota transplant is a good treatment for recurrent C.difficile and there were several randomized clinical… Continue reading GI Pearls Episode 57 Short

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Episode 56 – New Short Format Articles discussed: Once-only colonoscopy or two rounds of faecal immunochemical testing 2 years apart for colorectal cancer screening: preliminary report of a randomised controlled trial – Lancet Gastro Hep Vedolizumab is associated with a lower risk of Serious Infectious than Anti-Tumor Factors Agents in Older Adults – CGH please… Continue reading Episode 56 – Short

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Show notes for Episode 55 – June 2022 Pooled Rates of Adenoma Detection by Colonoscopy in Asymptomatic Average Risk Individuals with Positive Fecal Immunochemical Test: A Systematic Review and Meta-Analysis – GIE Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of IM Recurrence of Colorectal neoplastic polyps after incomplete resection  – annals of… Continue reading Episode 55 – June 2022 – Gastroenterology Literature Review

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Show notes Episode 54 – May 2022 A Randomized Controlled Trial of Cold Snare Polypectomy Technique: Technique Matters More Than Snare Wire Diameter – Am J Gastro Outcomes for upper gastrointestinal bleeding during the first wave of the COVID-19 pandemic in the Toronto area – J Gastro and Hep  Endoscopic Surveillance of Barrett’s Esophagus –… Continue reading Episode 54 – May 2022 – Gastroenterology Literature Review

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Show Notes for Episode 53 Lyophilised oral fecal microbiota transplantation for ulcerative colitis (LOTUS): a randomised, double-blind, placebo-controlled trial. – Lancet Gastro Effect of prophylactic endoscopic clip placement on clinically significant post-endoscopic mucosal resection bleeding in the right colon: a single centre, randomized controlled trial – Lancet Gastro Feasibility and diagnostic yield of small-bowel capsule… Continue reading Episode 53 – February 2022 – Gastroenterology Literature Review

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Episode 52 Show notes Immediate versus Postponed Intervention for Infected Necrotizing Pancreatitis – NEJM Benchmarking Adenoma Detection Rates for Colonoscopy: Results From a US-Based Registry – Am J Gastro Colonoscopy-related Mortality in a Fecal-Immunochemical Test-based Colorectal Cancer Screening Program – CGH AGA Clinical Practice Update on Endoscopic Surveillance and Management of Colorectal Dysplasia in IBD… Continue reading Episode 52 – November 2021 – Gastroenterology Literature Review

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Show notes for Episode 51 Role of routine second-look endoscopy in patients with acute peptic ulcer bleeding: meta-analysis of randomized controlled trials-  GIE A Randomized Trial Comparing the Specific Carbohydrate Diet to a Mediterranean Diet in Adults with Crohn’s Disease – Gastroenterology Comparative effectiveness and harms of antibiotics for outpatient diverticulitis. – Annals of IM… Continue reading Episode 51 – September 2021 – Gastroenterology Literature Review

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Histologic Changes caused by Injection of a novel submucosal lifting agent for endoscopic resection in GI lesions. – GIE Prevalence of Barrett’s Esophagus and performance of societal screening guidelines in an unreferred Primary care Population of US veterans.  – GIE The usefulness of olive oil enema in children with severe chronic constipation – J Ped… Continue reading Episode 50 – May 2021 – Gastroenterology Literature Review

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Show notes for Episode 49 for April 2021 Effectiveness of Oral Vancomycin for Prevention of Healtchare Facility-onset C.diff infection in Targeted Patients during Systemic antibiotic Exposure – Clinical ID The Detrimental Effects of oral Vancomycin – Letter to Editor – Clinical ID Linked color imaging focused on Neoplasm detection in the Upper GI tract –… Continue reading Episode 49 – April 2021 – Gastroenterology Literature Review

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Show notes for Episode  48 March 2021 Younger physicians and longer withdwaral times are associated with detection of advanced neoplasia in a large community practice. – CGH It’s All The RAVE: Time to Give up on “Chronic Radiation Proctitis” Misnomer – Gastroenterology Local immune response to food antigens drives meal-induced abdominal pain – Nature Prevalence… Continue reading Episode 48 – March 2021 – Gastroenterology Literature Review

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Show notes for Episode  47, January 2021 Endoscopic Recognition and management strategies for Malignant Colorectal Polyps: Recommendation of the US Multi-Society Task force on Colorectal Cancer – GIE Polyp morphology: an interobserver evaluation for the Paris classification among international experts – AmJ Gastro Outcomes in lower GI bleeding comparing weekend with weekday admission. – GIE… Continue reading Episode 47 – January 2021 – Gastroenterology Literature Review

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Show notes for Episode 46 for December 2020 Sequential endoscopist-driven phone calls improve capture rate of adverse events after ERCP: a prospective study – GIE  Regular use of proton pump inhibitors and risk of type 2 diabetes: results from three prospective cohort studies – GUT  Long-Term Consequences of Undiagnosed Celiac seropositivity –  Am J Gastro Hyperbaric… Continue reading GI Pearls – December 2020 – Episode 46 Gastroenterology Literature Review

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Show notes for Episode 45 for November 2020  Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude – CGH Early Colonoscopy Does Not Improve Outcomes of  Patients With Lower Gastrointestinal Bleeding: SRM – CGH  Adverse Events After Inpatient Colonoscopy in Octogenarians – J of Clinical Gastro Comparative Efficacy of Drugs for the Treatment… Continue reading GI Pearls – November 2020 – Episode 45 Gastroenterology Literature Review

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Show Notes for October 2020 – Episode 44 A Quarter of Participants With Advanced Neoplasia  Have Discordant Results From 2-Sample Fecal  Immunochemical Tests for Colorectal Cancer Screening – CGH Assessment of Clinical Conditions Associated with Splenic Infarction in Adult Patients – JAMA Internal Medicine Unsedated colonoscopy – impact on quality indicators – Dig Dis Sci The effect… Continue reading GI Pearls – October 2020 – Episode 44 Gastroenterology Literature Review

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Show notes for Episodes 43 – September 2020 Levels of Vitamin D are low after Crohn’s disease is established but not before –  CGH Rapid recurrence of EOE activity after successful treatment in the observational phase of a randomised trial. – CGH Clinical outcomes of adults with eosinophilic esophagitis with severe stricture. – GIE Quality… Continue reading GI Pearls – September 2020 – Episode 43 Gastroenterology Literature Review

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Show notes for Episodes 42 – July/August 2020 Use of total underwater colonoscopy to navigate endoscopic challenges – CGH Performance of radiographic imaging after incomplete colonoscopy for non-malignant causes in clinical practice. – GIE Cognitive Deficit and white matter changes in persons with celiac disease: a population based study. -Gastroenterology Endoscopic gastric body plication for… Continue reading GI Pearls – July 2020 – Episode 42 Gastroenterology Literature Review

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Show notes for Episodes 41 – June 2020 Discrepancy between self-reported and actual colonoscopy polypectomy practices for the removal of small polyps – GIE AGA Guidelines on the management of Moderate to Severe Ulcerative Colitis – Gastro  Resistance training increases muscle strength and muscle size in patients with liver cirrhosis. – CGH Reduced incidence of… Continue reading GI Pearls – June 2020 – Episode 41 Gastroenterology Literature Review

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Show notes for Episodes 40 – May 2020 Choosing a prokinetic for your patient beyond metoclopramide – AmJ Gastro Ultraprocessed Food Consumption and Risk of T2DM among participants of the NutriNet-Sante Prospective Cohort – JAMA Int Med Diagnosis and Treatment of Clostridioides (Clostridium) difficile  Infection  in Adults in 2020 – JAMA Clinical importance of cold polypectomy… Continue reading GI Pearls – May 2020 – Episode 40 Gastroenterology Literature Review

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Show notes for Episodes 39 – February-March 2020 Prevalence of colorectal cancer and advanced adenoma in patients with acute diverticulitis – GIE Pancreatic tuberculosis: A systematic review of symptoms, diagnosis and treatment – UEGJournal Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastro… Continue reading GI Pearls – March/April 2020 – Episode 39 Gastroenterology Literature Review

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Show notes for Episodes 38 – January 2020 ASGE review of adverse events in colonoscopy – GIE  Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia – NEJM Relationship Between Recreational Marijuana  Use and Bowel Function in a Nationwide Cohort Study – Am J gastro Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and  screening… Continue reading GI Pearls – January 2020 – Episode 38 Gastroenterology Literature Review

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Show Notes for December 2019 – Episode 37 Assessment of Publication Trends of Systematic Reviews and RCTs – JAMA Int Med. Association between Hpylori exposure and decreased odds of EOE – CGH Effect of anti-Hpylori therapy on incidence of autoimmune diseases,  – CGH AGA Practice Update on Surveillance for cancer in patients with PSC –… Continue reading GI Pearls – December 2019 – Episode 37 Gastroenterology Literature Review

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Show Notes for November 2019 – Episode 36 Detection of Various Microplastics in Human stool – Annals of int Med Herpes Zoster in Tofacitinib: Risk is Further Increased with Glucocorticoids but not Methotrexate – Arthritis Care Res Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae  – Cell Incidence of and Risk Factors for  Hepatic Encephalopathy in a Population-Based… Continue reading GI Pearls – November 2019 – Episode 36 Gastroenterology Literature Review

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Show Notes for Oct 2019 – Episode 35 Appropriate therapeutic drug monitoring of Biologic agents for Patients with IBD – CGH The View from Europe – TDM  – CGH  Cold snare vs Heparin bridging and hot snare polypectomy in patients on anticoagulants with subcentimeter polyps. – Annals of int Med. High-Dose Vitamin D Supplementation on… Continue reading GI Pearls – October 2019 – Episode 35 Gastroenterology Literature Review

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Discussing #FMT, Immunizations in #IBD patients, #ColonCancer guidelines, #DILI and much more!

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Show Notes for June 2019 – Episode 33 Epidemiology and implications of concurrent diagnosis of EOE and IBD – Gut Risk of Cdiff Infection with Systemic  Antimicrobial Therapy Following Successful FMT –   Dig Dis Sci Safety of Endoscopy in cancer patients with thrombocytopenia and neutropenia – GIE Same-Day vs Different-Day Elective Upper and Lower Endoscopic Procedures… Continue reading GI Pearls – June 2019 – Episode 33 Gastroenterology Literature Review

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Show Notes for May 2019 – Episode 32 Risk of postpolypectomy bleeding with uninterrupted clopidogrel therapy- an industry-indepentend, double-blind, randomized trial. – Gastroenterology Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study – GUT Cold snare endoscopic resection of nonpedunculated colorectal polyps larger than 10mm: A systematic review and pooled… Continue reading GI Pearls – May 2019 – Episode 32 Gastroenterology Literature Review

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Show Notes for April 2019 – Episode 31 Prediction of individuals at high absolute risk of esophageal squamous cell carcinoma – GIE Updates on Gastric Intestinal Metaplasia – Digestive Diseases Sci Thermal ablation of mucosal defect margins reduces adenoma recurrence after colonic EMR – Gastro Transfusion Strategies for Acute Upper Gastrointestinal Bleeding – NEJM  Effect… Continue reading GI Pearls – April 2019 – Episode 31 Gastroenterology Literature Review