EAU Podcasts: Recent Episodes

European Association of Urology

This is the official podcast channel of the European Association of Urology and the European School of Urology. The EAU Podcast is your source for the latest information across the full urological spectrum. Take your clinical practice to new heights and tune in!

In this episode, UROONCO PCa chief editor Dr. Giancarlo Marra interviews Prof. Mary-Ellen Taplin from Dana–Farber Cancer Institute in the United States, on the results of the PROTEUS trial.

The PROTEUS trial is a phase 3, double-blind, placebo-controlled trial evaluating the benefit of adding apalutamide to standard androgen deprivation therapy (ADT) in men with high-risk, localised prostate cancer undergoing radical prostatectomy.

They discuss the rationale, patient selection and the results of this trial (dual primary endpoint), as well as the impact of the results on clinical practice. Prof. Taplin concludes in the take-home messages that this trial has illustrated the progress being made in regard to preventing and delaying relapse.

To know more on this trial, read the abstract with expert commentary by UROONCO PCa associate editor Assoc. Prof. Pawel Rajwa.

For more updates on prostate cancer, please visit our educational platform UROONCO PCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, "Update in the management of recurrent urinary tract infection", Prof. Chris Harding, Prof. Gernot Bonkat, Assoc. Prof. Kathrin Bausch, Dr. José Medina-Polo and Dr. Carolina Ochoa Vargas discuss the latest evidence and practical approaches for managing recurrent urinary tract infections while supporting antimicrobial stewardship.

The episode explores non-antibiotic treatment and prevention strategies, including phytotherapy, immunoprophylaxis, vaginal oestrogen therapy and methenamine hippurate. The speakers review current EAU Guideline recommendations and examine the evidence behind emerging therapies aimed at reducing antibiotic use. Particular attention is given to the management of acute cystitis, prevention of recurrent infections and treatment considerations for patients with neurogenic lower urinary tract dysfunction.

The faculty also discuss patient selection, safety considerations and the role of shared decision-making when choosing between available treatment options. Throughout the episode, practical clinical insights are combined with the latest research findings to help clinicians optimise care for patients with recurrent urinary tract infections.

This podcast is brought to you in collaboration with the EAU Section of Infections in Urology.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

How should prostate biopsy be performed in the MRI era, and what impact does biopsy strategy have on treatment planning?

In this episode, Prof. Francesco Sanguedolce is joined by Prof. Francesco Giganti, Prof. Gianluca Giannarini and Prof. Lars Budäus to discuss the latest expert recommendations on prostate biopsy.

The conversation explores the importance of high-quality MRI, targeted and perilesional biopsy strategies, the role of emerging imaging technologies and the ongoing debate surrounding systematic biopsy.

The faculty also discuss how biopsy findings can influence decisions on focal therapy, nerve-sparing surgery and lymph node dissection, while highlighting current areas of consensus and the questions that still remain in clinical practice.

ProBIOPSY: A Multidisciplinary International Consensus on Standards for Prostate Biopsy, European Urology, article in press. Doi.org/10.1016/j.eururo.2026.06.012)

This podcast is brought to you in collaboration with the EAU Section of Urological Imaging.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Dr. Giuseppe Magistro (DE), Prof. Gernot Bonkat (CH) and Ass. Prof. Kathrin Bausch (CH) discuss the latest updates in the 2026 EAU Guidelines on Urological Infections.

They explore the growing importance of antimicrobial stewardship, including new non-antibiotic approaches for the treatment and prevention of cystitis. The speakers also highlight updated recommendations favouring the transperineal approach for prostate biopsy, with increasing evidence supporting reduced antibiotic use.

In addition, they discuss the newly introduced chapter on fungal urinary tract infections and the importance of distinguishing asymptomatic funguria from clinically relevant infections.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROLUTS associate editor Ms. Neha Sihra (GB) interviews Dr. Yasmin Heiniger (CH) about the abstract “Multi-institutional outcomes of robot-assisted simple prostatectomy: a retrospective study by the ERUS scientific reconstructive working group”, which she presented at AUA2026.

They discuss the different surgical techniques evaluated in this study and the results, including complications and post-operative management.

To know more on this study, read the abstract here.

For more updates on functional urology, visit UROLUTS educational platform.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO RCC chief editor Dr. Carmen Mir talks to Assoc. Prof. Pedro Barata from Case Western Reserve University, Ohio (US). They discuss the results of the ctDNA analysis in participants with renal cell carcinoma (RCC) treated with adjuvant pembrolizumab or placebo in the KEYNOTE-564 trial and the potential impact of these results for clinical practice.

Read the abstract of this trial to know more.

For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Dr. Francesco Del Giudice (IT), Prof. Antoine van der Heijden (NL), Prof. Richard Cathomas (CH) and Dr. Laura Mertens (NL) discuss the latest updates in the 2026 EAU Guidelines on muscle-invasive bladder cancer (MIBC).

They explore major changes in perioperative treatment strategies, including the introduction of immunotherapy-based combination treatments and evolving standards for cisplatin-eligible and ineligible patients. The speakers also discuss the growing role of ctDNA, mpMRI, and multimodal imaging in diagnosis, treatment response assessment, and bladder preservation strategies.

In addition, they highlight the importance of multidisciplinary collaboration, patient-centred care, psychological support, and shared decision-making in the rapidly evolving management of MIBC.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Ms. Neha Sihra (GB) and Prof. Thomas M. Kessler (CH) discuss the latest updates in the 2026 EAU Guidelines on neuro-urology.

They explore the growing importance of patient perspectives and shared decision-making in managing neuro-urological conditions, as well as ongoing discussions around single-use versus reusable catheters. The speakers also address challenges in defining and managing urinary tract infections in patients with underlying neurological diseases.

In addition, they discuss the future potential of neuromodulation therapies and updated recommendations regarding the use of botulinum toxin following failed antimuscarinic treatment.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Ass. Prof. Giancarlo Marra (IT), Prof. Derya Tilki (DE) and Prof. Philip Cornford (IE) discuss the latest updates in the 2026 EAU Guidelines on Prostate Cancer.

They explore changes in risk stratification, the evolving role of enzalutamide plus ADT in high-risk disease, and emerging diagnostic technologies such as micro-ultrasound and NeuroSAFE. The conversation also highlights advances in personalised treatment approaches for metastatic hormone-sensitive prostate cancer, including BRCA and PTEN-targeted strategies.

In addition, the speakers emphasise the growing importance of supportive care, bone protection, and managing long-term treatment-related side effects to improve patient outcomes.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

UROLUTS associate editor Dr. Cyrille Guillot-Tantay interviews Dr. Ahmed Albakr on the abstract he presented at AUA 2026 last month, “Evaluation of a novel midurethral sling for tissue compatibility and easier sling excision in porcine models”.

Dr. Albakr elaborates on the rationale of his study, and what the findings of this study tell us about tissue incorporation. They also discuss what the significant clinical advantages could be for patients when comparing to traditional polypropylene slings.

To know more on this study, read the abstract here.

For more updates on functional urology, visit UROLUTS educational platform.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 3, “Revalidation & lifelong learning” of the series “Start smart: EU-ACME for young urologists”, Prof. Marek Babjuk (CZ), Assoc. Prof. Juan Luis Vásquez (DK), Prof. Giorgio Ivan Russo (IT) and Dr. Loïc Baekelandt (BE) explore the importance of maintaining competencies in a rapidly evolving field.

The speakers reflect on revalidation, future career development, and the value of adopting a lifelong learning mindset. The conversation underscores how EU-ACME helps urologists stay current while preparing for the next stages of their professional journey.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

EAU History Office curator Dr. Rob Schipper (NL) and historian and author Mr. Loek Keizer (NL) talk about the earliest developments in endoscopy and how they dovetail with the rise of urology as a field.

Visit the EAU’s online European Museum of Urology for much more information on Bozzini and the first proto-endoscope and the further development of the Desormeaux endoscope.

Also mentioned in the conversation: the Josephinum in Vienna, Austria.

Check out the EAU’s historical publications. EAU:50 is free while stocks last!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

This EAUN episode features an interview with the faculty of the hands-on training on erectile dysfunction. Jeannette Verkerk-Geelhoed (NL), MSc, PhD candidate and CNS at St. Antonius Hospital, specialising in male sexual health including erectile dysfunction and Peyronie’s disease, is joined by Phil Reynolds (GB), MSc, BSc, HNC, radiographer at Clatterbridge Cancer Centre with a holistic focus on prostate cancer care, and Mariet Lenaers (BE), MSc, BN, prosthetic nurse at Virga Jesse Hospital, specialising in counselling patients undergoing prosthetic treatment.

Together, they reflect on the EAUN26 hands-on training session, focusing on the impact of sexual dysfunction in men and what it means for patients and their partners. The discussion highlights both the physical and psychological aspects of erectile dysfunction, as well as the importance of communication and patient education. The faculty also review current treatment options, including oral medication, vacuum devices, intracavernosal injections, and, as a final option, penile prosthesis.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 5, “AI in surgical navigation” of the series “AI in urology: From principles to practice”, Dr. Enrico Checcucci (IT) and Dr. Pieter De Backer (BE) discuss how artificial intelligence is changing the way urological surgery is planned and performed.

The episode explores how AI can assist with analysing CT and MRI imaging, automatically segment anatomical structures, and create patient-specific 3D models. The speakers explain how these digital models can support surgical planning, improve navigation during procedures and help surgeons better understand complex anatomy. They also discuss the importance of validating AI-generated models and maintaining clinical oversight.

In addition, their conversation looks at future developments such as digital twins, augmented reality, and more personalised approaches to surgery. Overall, the episode provides a practical overview of how AI may enhance precision and decision-making in the operating room.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO BCa chief editor Dr. Benjamin Pradere interviews Dr. Trinity Bivalacqua on the first results from CORE-008 Cohort CX- phase 2 study of intravesical cretostimogene grenadenorepvec with gemcitabine in patients with high-risk BCG-exposed or BCG-unresponsive non-muscle invasive bladder cancer.

They talk in detail of the rational and results of this cohort, and the role of cretostimogene in treatments of BCG-exposed or BCG-unresponsive bladder cancer.

For more details on this study, you can read the abstract on the UROONCO BCa Educational Platform.

This interview was recorded at AUA2026. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 4, “Large language models in urology” of the series “AI in urology: From principles to practice”, Assoc. Prof. Giovanni Cacciamani (US) and Dr. Pieter De Backer (BE) discuss the current and future role of large language models in urology.

The conversation explores how large language models tools can assist with clinical documentation, education, research and communication with patients. The speakers discuss the advantages of these systems, including improved efficiency and easier access to information. They also address important limitations, such as the risk of incorrect outputs, bias and the need for human oversight.

In addition, the episode highlights the importance of using these tools responsibly and understanding their capabilities and boundaries. Overall, the discussion provides a practical overview of how large language models may influence urological practice in the future.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 3, “AI policy in urology” of the series “AI in urology: From principles to practice”, Sarah Collen (BE) and Dr. Karl Kowalewski (DE) discuss the critical role of policy and regulation in the development and use of artificial intelligence in urology.

The conversation highlights why governance frameworks are essential to ensure patient safety, transparency and accountability. The speakers explore current regulatory challenges and the need for clear guidelines to support the responsible integration of AI into clinical practice. They also address ethical considerations, including data use, bias and trust in AI-driven decision-making.

In addition, the discussion considers how policy can both enable innovation and provide necessary safeguards. Overall, the episode offers a clear and practical overview of why policy matters in shaping the future of AI in urology.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 2, “AI in urology education” of the series “AI in urology: From principles to practice”, Prof. Bhaskar Somani (UK) and Dr. Pieter De Backer (BE) discuss the growing role of artificial intelligence in urological training and education.

The conversation focuses on how AI can support busy clinicians by improving efficiency, saving time, and enhancing access to educational resources. The speakers highlight practical applications of AI in daily learning, including content preparation and knowledge acquisition. They also address the importance of understanding AI tools to use them effectively and responsibly in clinical practice.

In addition, the discussion touches on the need for adapting training programmes to ensure future urologists are equipped with the necessary AI-related skills. Overall, the episode provides a balanced perspective on the opportunities and challenges of integrating AI into urology education.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 1, “Explainable AI in urology” of the series “AI in urology: From principles to practice”, Dr. Titus Brinker (DE) and Dr. Karl Kowalewski (DE) discuss the importance of transparency and trust in the use of artificial intelligence in healthcare.

The conversation focuses on explainable AI and why it is important for clinicians to understand how algorithms arrive at their recommendations. The speakers explore how AI systems can support clinical decision-making, but also why users need to understand their strengths and limitations. They discuss the importance of being able to interpret AI outputs and communicate them clearly to both clinicians and patients.

In addition, the episode highlights how explainability can help improve confidence in AI-supported healthcare. Overall, the discussion provides a practical introduction to one of the key challenges in AI implementation.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Dr. Paolo Capogrosso (IT) and Dr. Marij Dinkelman-Smit (NL) discuss “EAU guidelines updates on Sexual & Reproductive Health”.

The episode highlights the latest updates across key sections of the guidelines, including hypogonadism, penile curvature, priapism, and ejaculation disorders. Key changes include the removal of ineffective treatments, updates to conservative management strategies, and the introduction of new options such as hyaluronic acid for Peyronie’s disease.

The discussion also addresses important considerations in diagnosing hypogonadism, including proper testosterone measurement and distinguishing between functional and organic causes. Challenges related to limited high-quality evidence are emphasised, particularly in areas such as testosterone therapy in prostate cancer survivors and treatment options for ejaculation disorders.

Finally, updates to priapism management and treatment algorithms are outlined, reinforcing the importance of balanced, evidence-based recommendations to support clinical decision-making and improve patient care.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this EAU Podcast episode, Prof. Jean-Nicolas Cornu (FR) and Prof. Hashim Hashim (UK) discuss “EAU guidelines updates on Non-neurogenic Male LUTS”.

The episode highlights the latest updates to the EAU Guidelines on non-neurogenic male lower urinary tract symptoms, with a focus on a broader, symptom-based approach to diagnosis and management. Key developments include updated guidance on urodynamics, improved initial patient assessment, and the use of guideline algorithms available via the app.

The discussion also covers treatment updates, including new evidence on beta-3 agonists for storage symptoms and the continued role of established surgical options. Endoscopic enucleation is reinforced as the reference ablative treatment, while aquablation is highlighted as an increasingly supported alternative, particularly for patients wishing to preserve ejaculation. Emerging minimally invasive techniques are addressed, with emphasis on the need for further evidence before broader implementation.

The episode also introduces a new guideline chapter on detrusor underactivity and underactive bladder, marking an important expansion of scope. It concludes with the expectation that updates to the guidelines may become more frequent as new evidence continues to emerge in this rapidly evolving field.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 2, “Becoming a member & using EU-ACME” of the series “Start smart: EU-ACME for young urologists”, Prof. Marek Babjuk (CZ), Assoc. Prof. Juan Luis Vásquez (DK), Prof. Giorgio Ivan Russo (IT) and Dr. Loïc Baekelandt (BE) provide practical guidance on joining the programme and making effective use of its tools.

The speakers discuss how EU-ACME supports career progression, helps track educational activities, and encourages continuous professional growth. The episode offers clear insights for young urologists looking to actively manage their learning pathway.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this Journal Club edition of the EAU Podcast, moderator Prof. Thomas Tailly (BE) leads an in-depth conversation with guideline panel members Prof. Andreas Skolarikos (GR), Ass. Prof. Christopher Netsch (DE) and Prof. Otas Durutovic (RS), exploring how the EAU Guidelines on Urolithiasis are actually created, reviewed, and updated each year.

The speakers walk listeners through the methodology and workflow behind the guideline development process. They outline how the panel evaluates new evidence, conducts structured literature reviews, grades recommendations, and balances scientific rigour with clinical applicability. The discussion also highlights the timing and workload surrounding annual updates, the collaboration between full and associate panel members, and the importance of transparency when translating evolving evidence into practical recommendations.

Drawing on their personal experiences, the panel reflects on the challenges of harmonising diverse viewpoints, maintaining consistency across chapters, and adapting to rapidly expanding scientific data in stone disease. They also comment on how the guideline process has matured over time, emphasising quality control, internal peer review, and collective decision-making.

With clear explanations and candid insights “from inside the panel room”, this episode provides a rare behind-the-scenes look at how one of the most widely used urological guidelines is developed - and what it takes to keep it current, balanced, and clinically meaningful.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Recorded live at EAU26 in London, this special episode features a live recording of GU Cast, bringing a dynamic and interactive format to the congress stage.

Hosted by Prof. Declan Murphy (AU) and Prof. Renu Eapen (AU), the session brings together expert guests to discuss updates in prostate cancer guidelines, recent evidence, and key developments in urology. With contributions from the audience and a lively journal club segment, the episode offers a broad overview of current topics shaping clinical practice. Expect an engaging mix of expert insight, discussion and real-time interaction.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Recorded live at EAU26 in London, this special podcast episode features Prof. Brian Rini (US) and Prof. Tom Powles (GB)hosting an interactive UROmigos discussion with experts from the audience.

The session explores evolving treatment strategies and key debates in bladder and kidney cancer, highlighting emerging evidence and its potential impact on clinical decision-making.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO RCC chief editor Dr. Carmen Mir talks to Prof. Jose Karam on the results of the LITESPARK-022 study: Adjuvant pembrolizumab plus belzutifan versus pembrolizumab for clear cell renal cell carcinoma (ccRCC): The randomised phase 3 LITESPARK-022 study.

The LITESPARK-022 study will be also presented and discussed at the upcoming EAU26 on Saturday 14th March in the Game Changer Session. Don't miss the chance to hear more on this important study.

This interview was recorded at ASCO GU26. For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Prostate surgery in the United Kingdom was the domain of general surgeons for a relatively long time, discover why in this podcast. On the other hand, the UK has been leading the professionalisation and organisation of urological nurses. Both topics (and more) are the major topics at this year’s Historical Exhibition, part of the EAU Square (V14) in the EAU26 Exhibition.

Author and historian Mr. Loek Keizer (NL) of the EAU Central Office talks to urological surgeon and member of the EAU History Office Mr. Jonathan Goddard (GB) about that Office’s activities in London during EAU26.

Visit the Abstract Session mentioned in the podcast.
Prof. Van Kerrebroeck’s talk
Mr. Goddard’s talk.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO BCa chief editor Dr Benjamin Pradere (France) sits down with Matthew Galsky, Professor of Medicine at Icahn School of Medicine at Mount Sinai (New York, USA), to discuss the newly published results of the KEYNOTE-B15 trial.

This marks a truly pivotal moment for muscle-invasive bladder cancer. The presentation of KEYNOTE-B15 represents one of the most practice-changing advances in localised MIBC management in recent years, opening a new era of peri-operative systemic therapy and renewed hope for our patients.

KEYNOTE-B15 is a randomised phase III trial evaluating peri-operative enfortumab vedotin plus pembrolizumab in cisplatin-eligible patients with MIBC. In this in-depth discussion, Prof. Galsky walks us through the scientific rationale behind the study, the key efficacy and safety results, and crucially, how these data are likely to reshape clinical practice, not only in the immediate future but for years to come.
A must-listen conversation for urologists and multidisciplinary teams involved in the care of bladder cancer patients.

The KEYNOTE-B15 study will be also presented and discussed at upcoming EAU26 on Saturday 14th March in the Game Changer Session. Don't miss the chance to hear more on this important study and mark your agenda!

This interview was recorded at ASCO GU26. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this Journal Club edition of the EAU Podcast, Prof. Thomas Tailly leads a focused discussion on the recently completed APPEAL trial, a multicentre randomised controlled study evaluating whether routine antibiotic prophylaxis is necessary for patients undergoing extracorporeal shock wave lithotripsy (ESWL).

The distinguished panel - Prof. Kari Tikkinen, Prof. Zafer Tandogdu, Dr. Daron Smith, and Dr. Guido Kamphuis - explores the study’s design, recruitment challenges, outcome measures and the rationale behind examining antibiotic use in a procedure historically considered low-risk for infection.

They discuss variations in practice across centres, the balance between preventing rare infectious complications and avoiding unnecessary antibiotic exposure, and how the trial contributes valuable evidence in an area with limited high-quality data.

Throughout the episode, the panel reflects on how these findings align with current EAU recommendations and considers how the APPEAL trial can support future refinements in guideline statements. With a mix of expert insight, clinical reasoning and constructive debate, this episode offers listeners a clear understanding of the trial’s significance and its potential impact on everyday urological practice.

You can find the article to the APPEAL trial here.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 1, “Understanding EU-ACME / MyCME in daily practice” of the series “Start smart: EU-ACME for young urologists”, Prof. Marek Babjuk, Assoc. Prof. Juan Luis Vásquez, Prof. Giorgio Ivan Russo and Dr. Loïc Baekelandt introduce the EU-ACME programme and its role in supporting structured training and professional development.

They clarify key concepts, terminology, and membership types, helping listeners build a strong foundation for engaging with the system. Their discussion highlights how EU-ACME contributes to harmonising education and promoting high standards across European urology.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa associate editor Prof. Claudia Kesch (DE) interviews Dr. Jochen Walz (FR) about the key highlights of 2025 in low- to intermediate-risk prostate cancer.

They discuss advances in imaging diagnostics, artificial intelligence and biomarkers, active surveillance, surgical techniques and radiotherapy, as well as what is anticipated in 2026.

Here are the links to the articles and interviews on the trials which were mentioned in this podcast:

OPTIMUM Trial
PRIME Trial
BARCODE1 study
NeuroSAFE PROOF trial results
ENZARAD trial

For more updates on prostate cancer, please visit our educational platform UROONCO PCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

This EAUN episode is about understanding urinary tract infections (UTIs). Rikke Nygaard Knudsen, Clinical RN, EAUN Board Member and Chair of the Danish National Society, is joined by Susanne Vahr Lauridsen, Clinical RN, Senior Researcher, former EAUN Chair and EAUN guideline group member, for a practical and engaging conversation on everything there is to know about UTIs.

Drawing on extensive clinical and guideline experience, they unpack what a UTI really is, why it remains so common, and how to distinguish localised from systemic infections. The discussion brings guideline recommendations to life, with a strong focus on prevention and careful assessment rather than reflex antibiotic use. Particular attention is given to catheter-related UTIs, explaining why intermittent catheterisation should be preferred whenever possible.

With clear examples from daily practice, the episode translates EAUN guidance into actionable insights, empowering nurses to make informed decisions and improve patient outcomes.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 10, “My andrologist is a woman: Redefining expectations” of the series “Women in urology: Dare to thrive”, Dr. Marta Skrodzka (GB) and Dr. Nadja Stivalet (FR) explore how being a woman in andrology is reshaping professional practice and patient expectations.

Drawing on their clinical experiences, they discuss why female andrologists may offer a different dynamic in consultations, particularly in sensitive conversations around sexuality, fertility and male health. The speakers reflect on trust-building with patients and couples, challenging traditional assumptions about gender roles in andrology. They also address misconceptions about the specialty, emphasising that andrology extends far beyond prostate care and spans all stages of a patient’s life.

Through open dialogue, the episode highlights how visibility, communication style and empathy contribute to redefining what patients expect from their andrologist. Together, they make a compelling case for normalising and valuing women’s presence in this traditionally male-associated field.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa Associate Editor Assoc. Prof. Pawel Rajwa (PL) interviews medical oncologist Prof. Silke Gillessen Sommer (CH) about the present and future directions of metastatic prostate cancer treatment.

They discuss the greatest survival gains in metastatic prostate cancer over the past decade, triplet therapy in mHSPC and patient selection, the role of PSMA-PET imaging and sequencing of systemic therapies in metastatic prostate cancer, biomarker-driven treatment selection, and finally where the future of metastatic prostate cancer treatment is heading.

Here are the links to the articles and event which were mentioned in this podcast:

EORTC GUCG 2238 De-escalate trial
CAPItello-281 phase III study
APCCC (Advanced Prostate Cancer Consensus Conference)

For more updates on prostate cancer, please visit our educational platform UROONCO PCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode on “Public awareness of urinary tract infections and the fight against antimicrobial resistance”, Assoc. Prof. Z. Tandoğdu (TR) is joined by Prof. G. Bonkat (CH) and Mrs. J.M. Meijlink (NL) to address one of today’s most pressing global health challenges. UTIs are among the most common bacterial infections worldwide, yet they are often wrongly perceived as minor conditions. This misconception can lead to overuse or misuse of antibiotics, fuelling the rapid spread of antimicrobial resistance.

Prof. Bonkat shares insights from the EAU Guidelines on how responsible prescribing and clinical practice can help prevent unnecessary antibiotic use. Mrs. Meijlink shares the patient perspective, stressing the importance of accurate information and clear communication between doctors and patients.

Together, the speakers explore how awareness campaigns, education, and collaboration across healthcare and patient communities are essential to reducing the burden of UTIs. They emphasise that antimicrobial resistance already causes millions of deaths each year and requires urgent, coordinated action.

The discussion highlights practical steps for clinicians and patients alike, while reminding listeners that sustainable management of UTIs depends on both medical expertise and active public involvement.

Acknowledgment

This activity is supported by an educational grant from our industry partner - GSK, with no involvement in the programme or speaker selection.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

The UROONCO RCC editorial board chief editor Dr. Carmen Mir, and associate editors Dr. Teele Kuusk, Dr. Riccardo Bertolo and Assoc. Prof. Carlotta Palumbo share and discuss highlights of the important kidney cancer developments for 2025.

They summarise the developments in diagnostics and early detection, systemic therapy and perioperative treatment. They also talk about surgical and robotics innovations, tumour biology, and anticipated advances expected in 2026.

To learn more on the highlights discussed in this podcast, check out this report on kidney cancer highlights in 2025.

For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode "How can we optimise decision-making for complex/high-risk kidney stone patients?" Prof. Bhaskar Somani (GB) is joined by Dr. Matthew Breeggemann (US) and Dr. Timothy Bryant (GB) to explore the practical value and challenges of multidisciplinary collaboration in stone disease management.

The speakers reflect on how shared decision-making within a structured stone MDT can support better outcomes for complex or high-risk recurrent kidney stone patients. Using a real-life case example, they walk through the patient journey, examining how early specialist input and coordinated care can impact diagnosis, treatment planning and follow-up.

They discuss the current gaps in guideline implementation, particularly where patient complexity demands input beyond standard urological care. The role of nephrology, radiology and dietetics in MDT decision-making is highlighted, emphasising the need for clear communication and flexible protocols. The speakers also address challenges, such as delays in imaging or conflicting clinical opinions and how MDT formats can help resolve these through consensus-building.

The importance of tailoring care to individual risk profiles is underscored, along with suggestions for integrating MDT principles into both large and smaller healthcare systems. The episode concludes with practical recommendations for centres looking to establish or improve a stone MDT. This conversation provides valuable insight for clinicians involved in managing stone disease and those working toward more coordinated care models.

You can also listen to the previously released episode:

Identifying high-risk stone formers: How can we improve early diagnosis and referral? A discussion between Prof. Somani, Prof. Ferraro and Prof. Emiliani

Acknowledgment

Medical writing support was provided by Accenture Song Life Sciences with unrestricted funding from Novo Nordisk, with no involvement in the programme or speaker selection.

This EAUN edition of EAU Podcasts presents the latest update of the intravesical instillation guidelines, featuring insights from experts Bente Thoft Jensen RN, PhD, Susanne Vahr Lauridsen RN, PhD, and Lisbeth Leinum RN, PhD.

They discuss the key recommendations and changes since the previous version, as well as the impact on clinical practice, and how nurses and patients benefit from the guidelines.

They also outline the evidence-based development process of the guidelines and highlight the focus on nurse and patient safety, education, risk stratification and management of complications. The speakers emphasise growing evidence on managing side effects and the increasing attention to patient perspectives and quality of life.

A key message is the importance of improving patient adherence and ensuring nurses understand the differences between BCG and Mitomycin to maintain safety.

Host: Lisbeth Leinum, EAUN board member

Speakers: Bente Thoft Jensen, RN, senior researcher, chair of the Bladder Cancer SIG and the guideline panel; Susanne Vahr Lauridsen, RN, senior researcher, member of the guidelines panel.

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In Episode 9, “The urology resident perspective” of the series “Women in urology: Dare to thrive”, Dr. Kim Pauwaert (BE) and Dr. Francesco Ripa (IT) offer an honest and personal look into the realities of residency from both female and male perspectives.

Drawing on their training experiences in Belgium, Italy and the UK, they discuss the changing gender landscape in urology, the importance of visible role models and how mentorship shapes confidence and career choices.

Dr. Pauwaert shares candid reflections on balancing demanding training with societal expectations placed on women, including the challenges of long hours, family responsibilities and concerns around pregnancy risks for surgical trainees.

Together, they examine how work culture, flexibility and institutional support can improve the residency experience for all, regardless of gender. The episode closes with an optimistic view of the future, as both speakers note the growing presence of female urologists and the positive shift in patient and professional perceptions.

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In Episode 8, “Inclusivity challenge: Creating transformative culture” of the series “Women in urology: Dare to thrive”, Dr. Joe Philip (GB) and Dr. Silvia Proietti (IT) explore what true inclusivity looks like in modern urology and how cultural transformation begins with everyday behaviours.

Across their discussion, both speakers emphasise that inclusivity goes far beyond gender balance - it requires psychological safety, open communication and a willingness to question long-standing norms in surgical culture.

They discuss the importance of positive role models, supportive senior colleagues and transparent opportunities for career development, noting how these elements can empower young urologists regardless of background. Practical strategies emerge throughout their conversation, including active mentorship, equitable access to the operating room and consciously amplifying underrepresented voices.

Dr. Philip and Dr. Proietti also address the need for institutional commitment, reminding listeners that sustainable change depends on leadership engagement as much as individual effort. The episode ultimately offers a hopeful message: with intentional action and collective responsibility, urology can become a more inclusive, empowering and forward-thinking specialty.

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In this EAU podcast episode, UROONCO PCa associate editor Dr. Pawel Rajwa (PL), talks to Prof. Thomas Zilli (CH) on local therapy in metastatic prostate cancer.

This discussion was recorded at EMUC25. For more updates on prostate cancer, please visit our educational platform UROONCO PCa.

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In Episode 7, “Imposter syndrome and resilience” of the series “Women in urology: Dare to thrive”, Dr. Silvia Secco (IT), Dr. Rianne Lammers (NL) and Dr. Guido Cereda (IT) share open and personal reflections on imposter syndrome and the many forms it takes throughout a urological career.

They begin by acknowledging how common these feelings are - even among confident, accomplished clinicians - and discuss how new roles, transitions and increased responsibilities can intensify self-doubt.

Drawing on their own experiences, they explore how comparison, perfectionism and fear of inadequacy affect both trainees and senior doctors, often quietly and persistently. The speakers highlight the importance of supportive colleagues, mentorship and honest conversations, emphasising how validation from peers can help break the isolation many feel.

They also discuss practical approaches to building resilience, from reframing negative thoughts to recognising achievements and allowing space for vulnerability. Ultimately, the episode offers a reassuring message: imposter syndrome is widespread, manageable and best overcome together through openness, connection and shared understanding.

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UROONCO BCa associate edtiors Dr. Laura Mertens (NL) and Dr. Elisabeth Grobet-Jeandin (CH) talked to Prof. Lars Dyrskjøt (DE) about ctDNA in muscle invasive bladder cancer. To conclude this discussion, the associate editors also prepared some insightful rapid fire questions for Prof. Dyrskjøt.

This interview was recorded at EMUC25 in Prague. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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UROONCO BCa associate editor Dr. Elisabeth Grobet-Jeandin (CH) and Dr. Laura Mertens (NL) interview Dr. Laura Bukavina (US) on managing high-risk non-muscle invasive bladder cancer (NMIBC).

This interview was recorded at EMUC25 in Prague, Czech. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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UROONCO RCC chief editor Dr. Carmen Mir (US) talks to Dr. Lorenzo Bianchi (IT) on his lecture "RCC with venous thrombosis: optimal imaging for surgical planning and imaging-guided surgery".

This interview was recorded at EMUC25 in Prague. For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

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UROONCO RCC associate editor Assoc. Prof. Carlotta Palumbo (IT) talks with medical oncologist Dr. Pasquale Rescigno (GB) about his presentation supporting the 'yes' position in the debate at EMUC25: “Is single agent TKI (tyrosine kinase inhibitor) still an option in selected mRCC patients?

This interview was recorded at EMUC25 in Prague. For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

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In Episode 6, “The mentor perspective: Welcoming diversity” of the series “Women in urology: Dare to thrive”, Dr. Michelle Jo Semins (US) and Prof. Bhaskar Somani (GB) share their insights on how mentorship can shape more inclusive and equitable professional environments.

Drawing on their own experiences as mentor and mentee, they discuss how effective guidance can help overcome systemic barriers and support women in advancing their careers in urology. The conversation highlights the importance of recognising individual strengths, fostering confidence and creating opportunities that empower the next generation.

Both speakers emphasise that mentorship is not only about professional growth but also about personal connection, trust and the shared responsibility to promote diversity across all levels of academia and clinical practice. Together, they offer a thoughtful reflection on how inclusive mentorship can drive real change in the culture of urology.

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In Episode 5, “Role Models in Academic Urology: The WUO Perspective” of the series “Women in Urology: Dare to Thrive”, Dr. Sarah Psutka and Dr. Sima Porten reflect on the role of mentorship, collaboration and visibility through the lens of the Women in Urologic Oncology (WUO). They discuss how WUO has become a platform for fostering diversity, leadership and professional growth, creating opportunities for women to contribute to academic excellence and clinical innovation.

The speakers share how mentorship within WUO has helped strengthen global connections and inspired new generations of female urologists to pursue academic and leadership paths. They highlight the organisation’s achievements in promoting inclusivity, scientific exchange and balanced representation in urologic oncology.

This episode celebrates not only personal journeys but also the collective progress of women who are redefining academic success through shared purpose and collaboration.

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In Episode 4, “Women surgeons in Latin America: Leading change” of the series “Women in Urology: Dare to Thrive”, Dr. Catalina Solano Mendoza (CO) and Dr. Mariela Corrales Acosta (FR) discuss the evolving role of women surgeons in Latin America.

They share their personal experiences and reflect on the progress achieved through mentorship, collaboration and determination. Their conversation highlights the cultural and systemic challenges women still face across the region and the importance of creating networks that promote equal opportunities and professional growth. Both speakers emphasise that representation and solidarity are key to inspiring the next generation of urologists.

This episode celebrates the resilience and leadership of women who are driving lasting change in Latin American urology.

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UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks to Prof. Morgan Roupret (FR), on the results of the ALBAN trial. A phase 3, randomised, open-label, international study of intravenous atezolizumab and intravesical Bacillus Calmette-Guérin (BCG) vs BCG alone in BCG naïve high-risk, non-muscle invasive bladder cancer.

This interview was recorded at ESMO 2025 in Berlin, Germany. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks to Prof. Nicholas James (GB) on the results of the final survival analysis from the BladderPath trial, a randomised comparison of upfront magnetic resonance imaging versus transurethral resection for staging new bladder cancers.

This interview was recorded at ESMO 2025 in Berlin, Germany. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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In Episode 3, “Women surgeons in Asia – Pioneering progress” of the series “Women in Urology: Dare to Thrive”, Dr. Kinju Adhikari (NP) and Dr. Steffi Kar Kei Yuen (HK) share their experiences as pioneering female surgeons in Asia. Dr. Adhikari recounts her path from Nepal to becoming a leading onco-urologist and robotic surgeon in India, while Dr. Yuen reflects on her work at the Chinese University of Hong Kong and the evolving role of women in urology across the region. Together, they discuss the challenges of gender bias, the importance of perseverance and the growing number of women entering surgical specialities.

They highlight the vital role of mentorship, collaboration and supportive professional networks in fostering women’s progress in medicine. Both speakers emphasise that while representation has improved, barriers such as societal expectations and limited opportunities still exist. Their conversation explores how passion for patient care and clinical excellence can co-exist with advocacy for equality.

Through their exchange, the episode celebrates the determination of women surgeons shaping the future of urology in Asia and inspires the next generation to follow their lead with confidence and purpose.

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In this episode, Prof. Scott Tagawa (US), a medical oncologist atWeill Cornell Medicine in New York, discusses the results of PSMAddition - a phase III trial of [177Lu]Lu-PSMA-617 combined with ADT + ARPI in patients with PSMA-positive metastatic hormone-sensitive prostate cancer.

This interview was recorded at ESMO 2025 in Berlin, Germany. For more updates on prostate cancer, please visit our educational platform UROONCO PCa.

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UROONCO BCa chief editor Dr. Benjamin Pradere (FR) interviews Prof. Maria De Santis (DE) about the result of the final analysis of the phase III, open-label, randomised POTOMAC trial: Durvalumab (D) in combination with Bacillus Calmette-Guérin (BCG) for BCG-naïve, high-risk non-muscle-invasive bladder cancer (NMIBC).

This interview was recorded at ESMO 2025 in Berlin, Germany. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks to Prof. Christof Vulsteke (BE) on the design and results of the phase III KEYNOTE 905/EV303 study: Perioperative (periop) enfortumab vedotin (EV) plus pembrolizumab (pembro) in participants (pts) with muscle-invasive bladder cancer (MIBC) who are cisplatin-ineligible.

This interview was recorded at ESMO 2025 in Berlin, Germany. For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

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In Episode 2, “Academic career – The long and winding road?” of the series “Women in Urology: Dare to Thrive”, Dr. Amelia Pietropaolo (GB) and Dr. Carmen Mir (US) explore the opportunities and obstacles women face in building an academic career in urology. They highlight the persistence of gender gaps in leadership, the structural barriers that limit women’s access to networks and senior positions, and the pressures of balancing academia with personal life.

Both speakers emphasise the value of mentorship and sponsorship, sharing how role models and supportive colleagues helped them progress, while also reflecting on moments when barriers or cultural biases made the journey more difficult. They discuss positive shifts in recent years, including greater awareness of diversity at conferences and in academic societies, while questioning whether current measures go far enough.

Their conversation also touches on the importance of collaboration, networking, and building resilient research communities that encourage young urologists to thrive. Finally, they share personal advice for the next generation: seek mentors, stay curious, and remember why you chose research in the first place.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 1, “Leadership ladder: Creating your path” of the series “Women in Urology – Dare to Thrive”, Dr. Amelia Pietropaolo (GB) and Prof. Maria Ribal (ES) discuss the challenges and opportunities of pursuing leadership in a traditionally male-dominated specialty. Drawing on their personal journeys, they reflect on the persistence of gender stereotypes, the experience of imposter syndrome, and the importance of building confidence through knowledge, hard work, and supportive networks.

Their conversation emphasises that leadership is not about following a rigid master plan but about vision, long-term investment, and trust in one’s capabilities. Both speakers highlight the transformative role of mentorship and sponsorship, the value of inclusive groups in attracting more women into urology, and the importance of respecting individuality rather than conforming to stereotypes. Practical advice for young urologists includes taking small steps, embracing networking opportunities, and being unafraid to volunteer or step outside of one’s comfort zone.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In Episode 3 "Pharmaceutical preventative measures" of the series "How to prevent anxiety in children undergoing urological procedures", MSc. Gülhan Karaöz-Bulut (NL) and Dr. M. İrfan Dönmez (TR) discuss how medications can support anxiety reduction in paediatric urological care. They begin by emphasising that sedation should not be a goal on its own but part of a broader, child-centred strategy aimed at preventing trauma and building trust. The episode reviews several commonly used agents - nitrous oxide, midazolam, dexmedetomidine, clonidine and ketamine - with clear explanations of their benefits, limitations, and suitability for different procedures.

The speakers provide guidance on how each medication affects the child’s experience, with practical considerations such as onset time, duration, side effects and how they may impact diagnostic results. Special attention is given to the impact of sedatives on urodynamic studies, highlighting where certain agents (like dexmedetomidine or ketamine) may alter bladder function. They also address administration methods, such as intranasal and oral routes, and the importance of planning around food intake and hydration.

Throughout, the discussion underscores that medication should be tailored to the individual child and procedure, always supported by experienced clinical staff. The episode closes with a strong reminder that safe and effective sedation enhances both procedural success and the child’s well-being.

*See references and additional research information here

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In this episode, UROLUTS chief editor Dr. Giuseppe Magistro talks to Dr. Franziska Blobel on surgical treatments for benign prostatic obstruction (BPO).

For more updates on functional urology, visit UROLUTS educational platform.

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At DGU 2025 (Congress of the German Society of Urology), UROLUTS chief editor Dr. Giuseppe Magistro (DE) talks to Prof. Tamalunas (DE) about treatments for LUTS, with a focus on in vitro medicines.

For more updates on functional urology, visit UROLUTS educational platform.

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In Episode 2, “Non-pharmaceutical preventative measures" of the series "How to prevent anxiety in children undergoing urological procedures", Dr. Lisette ‘t Hoen (NL) and Dr. Sofie Schilling (NL) discuss how thoughtful, non-medication-based approaches can significantly ease procedural anxiety in children. Drawing from their experience at the Erasmus MC - Sophia Children’s Hospital, they share the importance of assessing each child’s age, emotional needs and prior medical experiences to tailor supportive care.

The conversation highlights the critical role of communication - not only with children but also with their families - as a foundation for trust and reassurance. The speakers explain how giving children a sense of control, even in small choices, helps reduce anxiety and increase cooperation. They present a range of effective tools, including bubble play, search-and-find books, stress toys and virtual reality headsets, each adapted to the child’s developmental stage.

Particular attention is given to cognitive distraction techniques that actively engage a child’s attention, leaving less mental space for fear. The episode also addresses what can be done during emergencies or at night when child life specialists are unavailable - emphasising that even small, simple gestures by clinical staff can have a big impact.

Finally, the discussion turns to newborns, often overlooked in anxiety prevention. The speakers explain how skin-to-skin contact, pacifiers, breastfeeding, and glucose water can all contribute to a calmer, less stressful experience, even in the earliest stages of life.

This episode offers highly practical insights for anyone involved in paediatric urological care - underscoring that anxiety prevention can often be achieved with empathy, creativity and the right non-pharmaceutical tools.

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UROONCO RCC associate editor Dr. Riccardo Bertolo (IT) talks to Prof. Jean-Christophe Bernhard (FR) about the lectures he presented during the ERUS25 Meeting.

Prof. Bernhard discusses surgical training for the next generation of urologists, sharing practical advice and guidance to help young surgeons grow in their careers, as discussed in his Young ERUS lecture.

He also shares details of his presentation on "Complex surgery of robotic nephrectomy in level 3 caval thrombus", and provides insights into treatment strategies, highlights the most critical preoperative considerations, and shares practical tips and tricks. He concludes with his opinion on whether robotic surgery represents the future for managing such challenging cases.

This interview was recorded at ERUS25 in London, United Kingdom. For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

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In “Episode 1” of the series "How to prevent anxiety in children undergoing urological procedures", Dr. Beatriz Bañuelos Marco (ES) and Dr. Michele Gnech (IT) discuss the basic principles of preventing anxiety, and the impact of urological procedures. Their discussion covers the core psychological and behavioural aspects that contribute to anxiety in children, particularly in the context of invasive urological procedures like catheterisation or surgery. They highlight the critical importance of preparing both the child and their caregivers, using age-appropriate language, clear explanations, and visual aids when necessary.

Dr. Gnech draws on his clinical experience to underscore how even common procedures can trigger stress responses if not handled with empathy and planning. Dr. Bañuelos Marco highlights how early assessment of a child's psychological state can help tailor supportive interventions. The discussion touches on the role of hospital environments, the use of distraction techniques, and the impact of parental anxiety on children's emotional regulation.

Together, they advocate for a multidisciplinary and preventative approach involving not just urologists, but also nurses, child psychologists and play therapists. The episode serves as an essential starting point for understanding how procedural anxiety can be mitigated with thoughtful communication, planning and compassion. This foundation sets the stage for more focused episodes later in the series, which will examine specific techniques and interventions.

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In this episode, Dr. Uchenna Kennedy (CH) talks about the growing importance of fertility preservation in pediatric patients, particularly those undergoing cancer treatment.

Dr. Kennedy explains the reasons behind adding fertility preservation to clinical guidelines, and the increasing survival rates of children with cancer. She also explores the effects of chemotherapy on the ovarian reserve in girls and the role of a pediatric multidisciplinary team in managing fertility preservation.

The episode covers various fertility preservation options, including ovarian tissue retrieval, oocyte retrieval, and ovarian transposition, as well as the outcomes and challenges associated with these procedures.

Shifting to boys, Dr. Kennedy addresses cryopreservation techniques, including sperm cryopreservation for postpbertal boys and the experimental status of testicular tissue cryopreservation for prepubertal boys.

Finally, she outlines the current state of these procedures and the ongoing advancements in the field.

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This podcast episode is the first in a series by the EAU’s History Office. Its chair, Prof. Philip Van Kerrebroeck (BE) is interviewed by EAU Editor and historian Loek Keizer (NL) about how electricity has been used for centuries to treat urological conditions.

From natural sources in ancient times, to generated power and its effects on the body to the current state of neuromodulation, find out from one of its experts how our understanding and applications of electricity have developed.

This podcast was recorded in Noordwijk, the Netherlands, on the occasion of the annual EAU Meets National Societies Meeting. Its contents are based on a presentation first given at the History Office’s Fall Meeting in Leiden in October 2024.

· Download the original presentation (PDF): https://tinyurl.com/39n6n4my

· Explore the European Museum of Urology: https://history.uroweb.org/

· Browse the books produced by the History Office: https://shop.uroweb.org/pages/books

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EAU Educational Platform UROLUTS associate editor Dr. Manuela Tutolo talks to guidelines panel chair Prof. Gernot Bonkat on updates on EAU Guidelines for urological infections.

This discussion took place during EAU25 in Madrid, Spain. For more updates on functional urology, please visit our educational platform UROLUTS.

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EAU edu platform UROLUTS associate editor Dr. Manuela Tutolo talks to guidelines panel members Prof. Chris Harding and Prof. Salvador Arlandis on the 2025 updates on EAU Guidelines for female LUTS. This expert discussion took place during EAU25 in Madrid, Spain.

For more updates on functional urology, please visit our educational platform UROLUTS.

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In this episode on "Identifying high-risk stone formers: How can we improve early diagnosis and referral?" Prof. Bhaskar Somani (GB) is joined by Prof. Pietro Manuel Ferraro (IT) and Prof. Esteban Emiliani (ES) to discuss timely and effective strategies for recognising patients with increased risk of kidney stone recurrence and complications.

The episode opens with the speakers sharing their clinical backgrounds - Prof. Ferraro as a nephrologist and Prof. Emiliani as an endourologist - laying the foundation for a multidisciplinary exchange. They reflect on challenges currently faced in clinical practice, including the delayed identification of patients who are predisposed to rapid stone formation, complex surgical pathways, or long-term renal complications.

Prof. Somani introduces the concept of the SMART Stone MDT and its potential to streamline patient care by enabling earlier recognition and appropriate referral. The discussion highlights the benefits of a structured, team-based model that incorporates both surgical and nephrology perspectives, aiming to reduce complications and improve outcomes.

Practical examples and real-world insights are shared throughout the episode, illustrating how MDTs can be integrated into everyday workflows. The conversation underlines the importance of collaboration, early intervention, and tailored patient pathways for high-risk stone formers, including those with primary hyperoxaluria or a solitary kidney.

This episode offers valuable takeaways for clinicians seeking to improve kidney stone care through early diagnosis and coordinated referral pathways.

Acknowledgment

Medical writing support was provided by Health Unlimited with unrestricted funding from Novo Nordisk, with no involvement in the programme or speaker selection.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO PCa chief editor Dr. Giancarlo Marra speaks to Prof. Derya Tilki (DE) about the 2025 updates in the EAU Prostate Cancer Guidelines, specifically regarding high risk, locally advanced disease and biochemical recurrence. This discussion includes changes such as the use of PSMA-PET-CT for staging, and updates related to lymphadenectomy.

In this EAUN edition of EAU Podcasts, you can listen to an inspiring conversation on Endourology – Implementation of Advance Nursing Practice, between Marta Marchetti (GB), Carmine Civilli (GB), and Dr. Susy Dal Bello (IT).

Dr. Dal Bello shares her groundbreaking journey in implementing advanced nursing practices and launching the first nurse-led flexible cystoscopy endoscopy clinic in Italy.

About the speakers:

Marta Marchetti

Marta is a highly skilled nursing professional from northern Italy. She graduated in nursing from the University of Padua in 2013 and earned a master’s degree in the diagnosis and surgical treatment of congenital heart disease in paediatric and adult patients in 2015. Marta’s career began as a surgical nurse, progressing to roles in the operating room as a scrub nurse in endourology and robotics, and later as a surgical assistant. In 2022, she completed a master’s in surgical care practice from Anglia Ruskin University (GB). Her expertise spans preoperative planning, intraoperative care, postoperative management, and patient follow-up. Marta is passionate about staff and patient education, which has led her to become actively involved with the EAUN and the Special Interest Group in Endourology and Robotics. Marta is currently working at The Royal Marsden Hospital in Chelsea (London), a centre of excellence and research for cancer treatment and care.

Carmine Civilli

Carmine is an experienced Surgical Care Practitioner with a strong background in perioperative multi-disciplinary cancer care and robotic-assisted surgery. Based in Manchester, he plays a pivotal role in service development across the region, especially in complex robotic procedures. Particularly interested in research design and data analysis, Carmine brings both clinical expertise and academic insight to the evolving field of robotic surgery. His work spans hands-on surgical practice, quality improvement, and staff education, including mentoring and contributing to national discussions. Carmine’s experience has also been shaped by his involvement in humanitarian surgical missions across African countries with Doctors Without Borders, where he supported surgical care delivery in resource-limited settings, an experience that continues to strongly influence his perspective on global health equity. His passion lies in improving patient outcomes through innovation and evidence-based practice, while advocating for the development and recognition of surgical practitioners within and beyond the robotic theatre. Carmine is also active in research and editorial writing, focusing on healthcare systems, surgical education, and frontline staff wellbeing.

Susy Dal Bello

Susy is a highly accomplished nursing leader from northern Italy. She graduated in nursing from the University of Padua in 2013 and earned a master’s degree in healthcare management in 2017. In 2023, she completed a master’s in nursing and midwifery sciences. Susy’s career began as a surgical scrub nurse, gaining extensive expertise in operating room procedures before advancing into a leadership role. Since 2019, she has served as the nurse manager of the multidisciplinary endoscopy unit, overseeing endoscopic procedures, staff management, and the strategic organization of the unit. Her expertise encompasses advanced clinical practice, leadership in healthcare management, and the coordination of multidisciplinary teams. Committed to professional development and education, she has been actively involved with the EAUN and the Special Interest Group in Endourology and Robotics since 2021. In 2023, she further expanded her international perspective through an observership at the Mayo Clinic in Rochester, Minnesota.

In "Episode 7" of the series on "Present and future of diagnostics in prostate cancer", Dr. Marcin Miszczyk (PL) and Prof. Wolfgang Fendler (DE) discuss the role of PSMA-PET imaging in modern prostate cancer management.

They examine how this advanced imaging modality compares to conventional techniques, and whether its improved sensitivity and specificity are enough to shift treatment paradigms. Drawing on key trials like proPSMA, ORIOLE, STORM, and RADIOSA, the episode highlights both the clinical value and the unresolved questions surrounding PSMA-PET, particularly regarding overdiagnosis, stage migration, and missed lesions.

Dr. Miszczyk and Prof. Fendler consider its potential in dose escalation, personalised therapy, and integration with MRI for better staging. They also reflect on upcoming changes in clinical guidelines, especially for high-risk patients, and share a hopeful outlook on the impact of PSMA-PET in shaping more precise and effective prostate cancer care.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In "Episode 6" of the series on "Present and future of diagnostics in prostate cancer", Assoc. Prof. Pawel Rajwa (PL) speaks with Prof. Peter Carroll (US) about the shifting landscape of active surveillance for intermediate-risk prostate cancer.

Traditionally reserved for low-risk cases, active surveillance is now being considered for select patients with grade group 2 disease - especially when diagnosed through advanced techniques like MRI-targeted biopsy.

Prof. Carroll explains how MRI has changed both the decision-making process and the biopsy approach, helping identify candidates with low risk of progression. The conversation addresses the potential to reduce overtreatment, minimise invasive follow-ups, and improve quality of life without compromising outcomes. Together, they examine how emerging data and imaging innovations are informing a more nuanced, patient-specific approach to prostate cancer care.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In "Episode 5" of the series on "Present and future of diagnostics in prostate cancer," Assoc. Prof. Henkjan Huisman (NL) and Dr. Alexander Ng (GB) discuss the exciting, yet controversial topic of artificial intelligence (AI) in prostate cancer diagnosis.

They examine where AI currently stands in the diagnostic pathway, including its role alongside MRI-guided biopsies. The discussion covers the progress AI has made in improving accuracy and efficiency in detecting prostate cancer, while also addressing the limitations and challenges that still exist.

The episode raises important questions about whether AI is truly transformative or if the excitement around it is just hype, offering a balanced view on its present and future impact in prostate cancer diagnostics.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this panel discussion, UROONCO RCC associate editor Dr. Teele Kuusk talks to EAU RCC guidelines panel members Prof. Axel Bex and Assoc. Prof. Saeed Dabestani on the 2025 updates in the EAU Guidelines for renal cell carcinoma (RCC).

Their conversation includes the impact of KEYNOTE-564 on adjuvant therapy, recommendations for stereotactic body radiotherapy (SBRT), surgical approaches, systemic therapies for papillary RCC, and new trial data. They also share insights into ongoing research on liquid biomarkers and perioperative treatment strategies.

In "Episode 4" of the series on "Present and future of diagnostics in Prostate Cancer", Dr. Rossella Nicoletti (IT) and Prof. Eva Compérat (FR) present the case against renaming Gleason score 6 Prostate Cancer.

They discuss the strong pathological arguments for keeping the "cancer" designation, pointing to the morphological and molecular evidence that supports this classification. Prof. Comperat highlights the risks of causing confusion within the clinical and research communities if Gleason score 6 were no longer considered cancer.

The episode also addresses the potential impact on prostate cancer reporting and the broader implications for treatment decision-making. This discussion presents a compelling counterpoint to the proposal of renaming Gleason score 6, emphasising the importance of consistency in cancer classification.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

The panel chair of the EAU guidelines on MIBC, Assoc. Prof. A. Van Der Heijden discusses the new updates with panel members Dr. L. Mertens and Prof. P. Mariappan.

You can view the newest Muscle-invasive and Metastatic Bladder Cancer EAU Guidelines, or download EAU Guidelines App. The app helps to optimise your search with interactive tools to quickly get the answer you need from the best-practice clinical guidelines for urologists. EAU members get full access, and non-members can explore with a 30-day free trial.

In "Episode 3" of the series on "Present and future of diagnostics in prostate cancer", Assoc. Prof. Paweł Rajwa (PL) and Prof. Scott Eggener (US) engage in a thought-provoking discussion about renaming Gleason 6 (Grade Group 1) prostate cancer.

The episode digs into the reasons why many experts believe this change is necessary, and the potential benefits it could bring to clinical practice, particularly in reducing overdiagnosis/overtreatment and improving patient outcomes. Prof. Eggener discusses the argument that Gleason 6 (Grade Group 1) might not behave like typical cancer, as it rarely leads to metastasis or death, and that renaming it could positively guide management decisions, particularly with active surveillance.

The conversation touches on the implications of this change on prostate cancer screening and how it could alter the way clinicians approach diagnosis and treatment in the future.

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At the American Urological Association's 2025 Annual Meeting in Las Vegas, Dr. Félix Guerrero-Ramos (ES) presented the first results from cohort 4 of the SunRISe-1 study, assessing TAR-200 monotherapy in patients with Bacillus Calmette-Guérin (BCG) - unresponsive papillary-only high-risk non-muscle-invasive bladder cancer.

In this episode, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) interviews Dr. Guerrero-Ramos about the study’s design, a detailed discussion of the results, comparisons with other trials such as BOND-003, and the implications for clinical practice.

For more updates on bladder cancer, please visit our educational platform UROONCO BCa.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

At the 2025 American Urological Association (AUA2025) Meeting in Las Vegas, UROONCO RCC associate editor Dr. Riccardo Bertolo (IT) spoke with Prof. Riccardo Autorino (US) about multi-port and single-port surgery options for kidney cancer.

Prof. Autorino shares expert insights on the key features of both surgical platforms, discussing their advantages and disadvantages, as well as considerations for selecting the most suitable patients for each approach.

For more updates on kidney cancer, please visit our educational platform UROONCO RCC.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

At the 2025 American Urological Association (AUA 2025) Meeting in Las Vegas, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talked to Dr. Neal Shore (US) about the CREST study results: Sasanlimab in combination with bacillus calmette-guérin (BCG) improves event-free survival (EFS) versus bacillus calmette-guérin as standard of care in high-risk non- muscle-invasive bladder cancer (NMIBC).

Dr. Shore explains the study rational, the results of the study, and the take home messages he presented during the meeting.

UROONCO PCa chief editor Dr. Giancarlo Marra talks to Prof. Phil Cornford on the updated EAU Prostate Cancer Guidelines for 2025, specifically on diagnosis and localised disease.

Their conversation focuses on key updates in active surveillance, diagnosis, and treatment of localised disease.

In "Episode 2" of the series on "Present and future of diagnostics in prostate cancer," Prof. Monique Roobol (NL) and Dr. Tamás Fazekas (HU) review the ongoing debate surrounding prostate cancer screening.

They review the history and development of screening strategies, including the key findings from early trials and the progression toward more personalised, risk-stratified approaches.

Prof. Roobol discusses the significance of PSA testing and how it serves as a tool for initial risk stratification, while also addressing the role of advanced techniques like MRI and novel biomarkers in improving screening accuracy. The episode also highlights the need to balance the benefits of early detection with the risks of overdiagnosis, and the speakers share their insights into how the latest clinical trials are shaping the future of prostate cancer screening.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In "Episode 1" of the series "Present and future of diagnostics in prostate cancer," Assoc. Prof. Juan Gomez Rivas (ES) and Dr. Elena Castro (ES) explore the importance of genomics and biomarkers in localised prostate cancer.

The episode reviews why these diagnostic tools are pivotal in the changing landscape of prostate cancer, offering a deeper understanding of their current and future role in patient care.

Assoc. Prof. Gomez Rivas and Dr. Castro discuss how these advancements in molecular profiling and biomarker testing can revolutionise the diagnosis and management of prostate cancer. Their conversation highlights the evolving nature of prostate cancer diagnosis, offering valuable perspectives on how genomics and biomarkers are shaping the future of personalised treatment strategies.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode of EAU Podcasts, Prof. Guy Bogaert and Prof. Christian Radmayr, the vice-chair and chair of the Paediatric Urology Guidelines Panel, discuss the latest updates to the EAU Guidelines on paediatric urology. Tune in to learn about the 2025 updates.

In ‘Episode 4’ of the series “Effective performance and personal success”, Assoc. Prof. Juan Luis Vasquez (DK) and Mr. Jason Howlett (DK) explore habit formation and its impact on personal and professional growth.

They discuss how consistent actions lead to significant long-term results, offering insights into how habits are formed and sustained. This episode explores strategies for reinforcing positive behaviours, overcoming obstacles to habit change, and using science-backed techniques to make new routines stick.

Join us to learn how to take control of your habits and build a foundation for lasting success.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In ‘Episode 3’ of the series “Effective performance and personal success”, Assoc. Prof. Juan Luis Vasquez (DK) and Mr. Jason Howlett (DK) explore the role of attention management in maintaining productivity and achieving personal success.

They discuss practical strategies to enhance focus, reduce distractions, and create an environment that supports deep work. The episode also covers techniques for managing digital interruptions, sustaining concentration over long periods, and structuring tasks to align with cognitive energy levels.

Join us for an insightful conversation on how to take control of your attention and work more effectively.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In ‘Episode 2’ of the series “Effective performance and personal success”, Assoc. Prof. Juan Luis Vásquez (DK) and Mr. Jason Howlett (DK) dive into the topic of energy management.

They discuss how optimising physical, mental and emotional energy can lead to sustained high performance and overall well-being. The episode covers key factors such as sleep, movement, and recovery, along with strategies to manage stress and prevent burnout. The speakers also share practical techniques for maintaining focus and productivity throughout the day.

Join us for an insightful conversation on how to manage your energy effectively and perform at your best.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In ‘Episode 1’ of the series “Effective performance and personal success”, Assoc. Prof. Juan Luis Vásquez (DK) and Mr. Jason Howlett (DK) discuss the crucial topic of time management.

They explore how effective prioritisation, planning and structured workflows can improve both productivity and personal success. The discussion covers practical strategies for optimising daily schedules, managing competing demands, and maintaining focus amid distractions. The speakers also share their perspectives on overcoming common time management challenges and building sustainable habits for long-term efficiency.

Join us for an insightful conversation filled with actionable advice to help you take control of your time!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, UROONCO kidney cancer chief editor Dr. Carmen Mir talks to Assoc. Prof. Tian Zhang from UT Southwestern Medical Center (USA). Assoc. Prof. Zhang shares an overview on the trial results of metastatic kidney cancer (mRCC) that were discussed at ASCO GU25. These trials include CheckMate-9ER, COSMIC-313, KEYMAKER-U03, LITESPARK-011. Assoc. Prof. Zhang gives her expert opinion on how these trials could impact clinical practice on first-line kidney cancer treatment.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this podcast interview recorded at ASCO GU25, UROONCO bladder cancer chief editor Dr. Benjamin Pradere talked to Dr. Nadine Houede from CHU Nîmes, Hospital Caremeau in France, on the results of the iNDUCT trial.

The iNDUCT trial is a phase II trial evaluated safety and efficacy of neoadjuvant chemotherapy (cisplatin or carboplatin + gemcitabine) in combination with durvalumab in these patients. Dr. Houede discusses the rational, the results and next steps.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Welcome to another EAUN edition of EAU Podcasts! In this episode, Ms. Anna Mohammed and Ms. Marta Marchetti introduce the Special Interest Group (SIG) in Endourology and Robotics.

Beginning with a brief introduction, Ms. Mohammed and Ms. Marchetti share details of what the SIG hopes to achieve, current developments, and how other nurse specialists can join the group.

Hosts:

Ms. Anna Mohammed – Originally from Trinidad, she graduated from the University of Hertfordshire in 2004. She began her career in theatre, progressing to Theatre Sister with a specialist interest in robotics, gynaecology, and urology. She later trained as a surgical care practitioner, earning a Master’s in surgical care practice (urology) in 2015 and qualifying as an independent prescriber in 2021. Passionate about education, she has developed training for theatre staff and surgical practitioners. As Chair of the Endourology and Robotics SIG with the EAUN, she promotes evidence-based practice internationally. She currently works at Cleveland Clinic, London (GB).

Ms. Marta Machetti – A skilled nursing professional from northern Italy, Marta graduated in Nursing from the University of Padua in 2013 and earned a Master’s in the Surgical Treatment of Congenital Heart Disease in 2015. She advanced from a surgical nurse to a scrub nurse in endourology and robotics, later becoming a surgical assistant. In 2022, she completed a Master’s in Surgical Care Practice at Anglia Ruskin University. Her expertise covers all surgical phases, and she is dedicated to staff and patient education. Actively involved in the EAUN, she now works at The Royal Marsden Hospital in Chelsea, a leading cancer treatment and research center.

In this episode, Dr. Nazim Gherabi (DZ) discusses his systematic review on the treatment of urge incontinence in postmenopausal women.

Dr. Gherabi talks about the most effective therapeutic approaches, and evaluates current evidence. He highlights gaps in research and offers insights into tailoring treatments to improve patient outcomes. This episode provides valuable perspectives for clinicians and researchers interested in advancing care for this prevalent condition in postmenopausal women.

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In this episode, Dr. Benjamin Pradere (FR) interviews Dr. Markus Eckstein (DE) to explore how artificial intelligence is revolutionising the field of bladder cancer pathology.

The discussion focuses on the role of AI in deciphering tumour complexity, improving diagnostic accuracy, and enhancing our understanding of this challenging disease. Dr. Eckstein shares insights into recent advancements, potential clinical applications, and the challenges of integrating AI into routine pathology workflows. This episode offers a compelling look at the intersection of technology and medicine, highlighting the future of AI-driven solutions in oncology.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, Dr. Alexander Glaser (US) explores the relationship between genetic predisposition and lifestyle in benign prostatic hyperplasia (BPH).

Drawing on data from a UK Biobank cohort study, he investigates whether varying levels of physical activity can modulate genetic risk factors for BPH. Dr. Glaser provides a detailed overview of the study's methodology, key findings, and potential implications for preventive and personalised approaches to managing prostate health. This episode sheds light on the critical intersection of genetics and lifestyle in addressing urological conditions.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

At the Turin Oncology Prostate Cancer Masterclass, UROONCO prostate cancer chief editor Dr. Giancarlo Marra talked to Prof. Bernardo Rocco from the Policlinico Gemelli and Università Cattolica in Rome (IT), on the new robotic technologies in prostate cancer, especially the technology of telesurgery and training.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

The UROONCO RCC editorial board chief editor Dr. Carmen Mir, and associate editors Dr. Teele Kuusk and Dr. Riccardo Bertolo share highlights of the important kidney cancer developments for 2024.

They summarise the results on several important trials such as FASTRACK, ZIRCON, KEYNOTE-564 and IMmotion010. They also discuss the developments on surgical aspects too.

To learn more on the highlights discussed in this podcast, you can read the below Articles of the Month, listen to the podcasts or watch the videos.

Stereotactic ablative body radiotherapy for primary kidney cancer (TROG 15.03 FASTRACK II): a non-randomised phase 2 trial
[89Zr]Zr-girentuximab for PET–CT imaging of clear-cell renal cell carcinoma: a prospective, open-label, multicentre, phase 3 trial
ASCO GU24 special: Assoc. Prof. Barata discusses the results of KEYNOTE-564 and CheckMate-914
ASCO GU24 special: Prof. Michael Hofman talks about a novel CA IX-targeting peptide
ASCO2024 special: Circulating kidney injury molecule-1 biomarker analysis in IMmotion010Present and future of robotic surgery for RCC
The treatment of locally advanced and metastatic renal cancer

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, Google Podcasts.

In 'Episode 7' of the series "Exploring urology: A roadmap for medical students", Assoc. Prof. Juan Gómez Rivas (ES) and Mrs. Sarah Collen (BE) discuss "Opportunities beyond the clinic – leadership, academia, and advocacy".

They highlight how urologists can shape the future of healthcare by taking on leadership roles, contributing to academic research, and championing patient advocacy on a global scale. With their experiences, they discuss the rewards and challenges of pursuing these non-clinical avenues. Whether guiding institutional strategy, advancing cutting-edge research, or influencing policy for better urological care, these opportunities add depth and purpose to a urologist’s career. This episode invites medical students to envision a broader, impactful future in urology that goes beyond the operating room.

Whether you’re considering urology as a career or are simply curious, listen in as we uncover why urology is an essential part of modern healthcare - and an exciting career path!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In 'Episode 6' of the series on "Exploring urology: A roadmap for medical students", Prof. Michiel Sedelaar (NL) and Prof. Ian Pearce (GB) discuss "A day in the life of a urologist".

This engaging conversation covers the multifaceted nature of urological practice, exploring the balance between clinical care, surgeries, research, and patient interaction. By sharing their personal experiences, Prof. Sedelaar and Prof. Pearce aim to inspire and inform students considering urology as a future career. Their dialogue offers a realistic, yet exciting glimpse into the profession, illustrating the profound impact a urologist can make on patients' lives.

Whether you’re considering urology as a career or are simply curious, listen in as we uncover why urology is an essential part of modern healthcare - and an exciting career path!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In 'Episode 5' of the series on "Exploring urology: A roadmap for medical students", Prof. Marcio Moschovas (US) and Dr. Angelo Territo (IT) discuss "Cutting-edge technology and innovations in urology".

They explore the rapid advancements in urological practices, highlighting the pivotal role of robotic surgery in improving surgical outcomes and enhancing precision.

The episode offers insights into how these technologies are reshaping the urological landscape, making complex procedures less invasive and more patient-centred. From discussing their personal experiences with robotic systems to examining how innovations are driving the field forward, this episode provides a compelling look into the future of urology.

Whether you’re considering urology as a career or are simply curious, listen in as we uncover why urology is an essential part of modern healthcare - and an exciting career path!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In 'Episode 4' of the series on "Exploring urology: A roadmap for medical students", Prof. James N'Dow (GB) and Dr. Paweł Rajwa (PL) discuss "Urological research and clinical trials".

Together, they discuss the critical role of research in advancing urological care, offering insights into the complexities of clinical trials and their impact on patient outcomes. Prof. N'Dow and Dr. Rajwa share their experiences in the field, emphasising the need for curiosity and a dedication to evidence-based medicine.

Whether you’re considering urology as a career or are simply curious; Listen in as we uncover why urology is an essential part of modern healthcare - and an exciting career path!

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In episode 3 of the series "Exploring urology: A roadmap for medical students", Ass. Prof. Giancarlo Marra (IT) and Dr. Rossella Nicoletti (IT) discuss "Urology as a career choice".

This is an enthusiastic talk about the unique appeal of urology, highlighting its dynamic mix of surgical precision, patient-focused care, and opportunities for innovation. Ass. Prof. Marra and Dr. Nicoletti address common misconceptions about the specialty, explore diverse career paths, and share practical advice on training and mentorship. With insights into the rewards and challenges of urology, this episode aims to inspire and guide medical students as they consider their future in this exciting field.

In 'Episode 2' of the series on "Exploring urology: A roadmap for medical students", Dr. Roderick Van Den Bergh (NL) and Dr. Katharina Beyer (NL) speak about "The impact of urology on public health".

Dr. Van Den Bergh and Dr. Beyer discuss the importance of urology in public health, emphasising early diagnosis and treatment for common diseases such as kidney stones and various cancers. They also highlight the role of organisations like the European Association of Urology in raising global awareness and supporting prevention initiatives. The episode concludes with insights into understanding and addressing the educational needs of different populations concerning urological health.

Join us as we uncover why urology is not only an essential part of modern healthcare but also a dynamic and rewarding career choice.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

Prof. Jens Bedke (DE) talks about two key topics from this year's EMUC24 kidney cancer sessions: the role of cytoreductive nephrectomy, and the SUNNIFORECAST trial (prospective randomised phase 2 trial of ipilimumab + nivolumab versus standaard of care in non-clear cell RCC.)

This informative episode was recorded at the 16th European Multidisciplinary Congress on Urological Cancers (EMUC24) in Lisbon, Portugal.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In 'Episode 1' of the series on "Exploring urology: A roadmap for medical students", Prof. Henk Van der Poel (NL) and Dr. Alexander Ng (GB) introduce the field of urology, offering insights into its broad scope and unique appeal.

In "Introduction to urology" Prof. Van der Poel and Dr. Ng discuss how urology combines surgical precision with medical innovation, covering everything from common treatments to advanced technologies that improve patient care. Highlighting urology’s pivotal role in healthcare, they emphasise the opportunities for specialisation and close collaborations with other disciplines.

Join us as we uncover why urology is not only an essential part of modern healthcare but also a dynamic and rewarding career choice.

At ICS24 (International Continence Society Annual Meeting), Dr. José Batista (ES) presented his abstract, “Artificial intelligence to read urodynamic tracings: Could we skip a human reading?”. In this episode of EAU Podcasts, Dr. Batista discusses the rationale and key findings of his study, exploring whether AI can interpret CMG traces reliably enough to be integrated into daily clinical practice.

To learn more on this study, read the abstract here.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this interview from UROonco24, Dr. Juan Gómez Rivas (ES) and Dr. Ursula Vogl (CH) discuss advancements in genomic profiling and the use of PARP inhibitors in treating metastatic prostate cancer, with a focus on genomic profiling, patient selection and toxicity management.

This activity is supported by an educational grant from a Pharmaceutical company, with no involvement in the programme or speaker selection.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this episode, Dr. Martin Stentebjerg Skøtt (DK) presents findings from a recently published systematic review on the topic of "Endoscopic balloon dilatation and incision for treating primary obstructive megaureter in children".

Historically, ureteral re-implantation has been the gold standard for addressing primary obstructive megaureter (POM) in children, but its challenges, particularly in infants, have spurred interest in less invasive methods. Dr. Skott discusses the effectiveness, safety, and benefits of endoscopic management as an alternative to the traditional surgical approach.

Dr. Skøtt also discussses potential complications, the need for long-term follow-up, and the importance of future research to refine treatment protocols for better patient outcomes.

Join us for this insightful conversation as Dr. Martin Skott sheds light on cutting-edge approaches to managing primary obstructive megaureter in children. Tune in and stay informed!

In this interview, medical oncologist Dr. Elena Castro (ES) and Dr. Gianluca Giannarini (IT) discuss the challenges of managing treatment-related toxicity and quality of life for PCa patients, particularly hormone-sensitive patients.

This activity is supported by an educational grant from a Pharmaceutical company, with no involvement in the programme or speaker selection.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

In this interview recorded at UROonco24 in Budapest earlier in the year, Dr. Gianluca Giannarini (IT) talks with Prof. Geert De Meerleer (BE) about the quality of life for patients with metastatic prostate cancer (mPCa) that are undergoing treatment. Their conversation features the role and safety of radiation therapy in patients with de novo metastatic hormone sensitive prostate cancer.

This activity is supported by an educational grant from a Pharmaceutical company, with no involvement in the programme or speaker selection.

In 'Episode 3' of the series "Voices of tomorrow's urologists (ESRU): Journeying through Europe's resident perspectives", Dr. Enrico Checcucci (IT) and Assoc. Prof. Stefano Puliatti (IT) discuss "Surgical training unveiled: Exploring new tech and standardisation trends".

This insightful talk highlights the evolving landscape of urological surgical training, addressing the integration of new technologies such as 3D printing and virtual simulators. The conversation also underscores the need for standardised training pathways and explores the challenges posed by the heavy reliance on patient-based training in the early stages of the learning curve.

Dr. Checcucci shares key findings from a Europe-wide survey on surgical training, shedding light on the current gaps and future directions. The episode offers valuable perspectives on how young urologists can benefit from a more structured and technologically enhanced training environment to ensure better surgical outcomes.

This EAU podcast has been developed with financial support from Pfizer Inc for healthcare professionals based in the EU and UK. The content discussed here was up to date at the time of recording in June 2024 and may not be suitable in your local market. The EAU has retained full editorial control.

In this episode, the panel chair of the EAU guidelines on prostate cancer, Prof. Philip Cornford (GB) is at UROonco24 in Budapest, and talks to medical oncologist Dr. Ursula Vogl (CH) on the role of genetic testing for prostate cancer.

Dr. Vogl discusses why genetic testing is important, and defines both somatic (tissue) testing, and germline testing. She shares her opinion on why ideally both should be done, and when, as well as an explanation of the guidelines.

To keep updated on prostate cancer developments, go to the UROONCO Prostate Cancer Educational Platform.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, EAU YouTube channel.

PP-UNP-GBR-10244. September 2024

In this podcast recorded live at ESMO 2024 in Barcelona, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talked to Prof. Hiroshi Kitamura (JP) about his presentation on the JCOG1019 study results: An open-label, non-inferiority, randomised phase III study comparing the effectiveness of watchful waiting (WW) and intravesical Bacillus Calmette-Guérin (BCG) in patients with high-grade pT1 (HGT1) bladder cancer with pT0 on the second transurethral resection (TUR) specimen.

Prof. Kitamura shares details of the study rationale, summarises the results, and discusses how these results could be implemented into clinical practice.

UROONCO BCa chief editor Dr. Benjamin Pradere talks to Assoc. Prof. Andrea Necchi (IT) at EMSO 2024 on the results of the interim analysis of SunRISe-4 study: TAR-200 plus cetrelimab or CET alone as neoadjuvant therapy in patients with muscle-invasive bladder cancer who are ineligible for or refuse neoadjuvant cisplatin-based chemotherapy.

Assoc. Prof. Necchi shares details of the study rationale and design, followed by an analysis of the results, and how these data could positively impact the future of treatment options for patients.

According to Assoc. Prof. Necchi, the SunRISe-4 study results show for the first time that an intravesical treatment with TAR-200, combined with a systemic PD-1 inhibitor, could potentially result in a complete pathological response in a high proportion of patients.

In 'Episode 2' of the series on "Voices of tomorrow's urologists (ESRU): Journeying through Europe's resident perspectives", Dr. Chechilia Maria Cracco and Dr. Luis Enrique Ortega Polledo discuss "Inside endourology: Resident perspectives exposed".

Hear about the unique challenges and rewarding experiences residents encounter in the specialised field of endourology. This discussion highlights the innovations shaping this area, offering insight into the learning process that residents undergo. Listeners will hear about endourology training and what residents find most engaging in their daily work. This episode provides a closer look at the evolving techniques and technology in urology, from the perspective of future specialist.

In this episode on "Prostate cancer indication for biopsy and screening", Dr. Roderick van den Bergh (NL) and Dr. Erik Briers (BE) discuss the dynamics of prostate cancer diagnostics, and the latest advancements in screening methods, including the updates to diagnostic algorithms that are reshaping clinical practices.

The discussion covers the role of prostate biopsies in detecting cancer, focusing on when they are most beneficial and how they impact patient outcomes. Dr. Briers also shares insights from the patient perspective, emphasising the importance of informed decision-making.

In this episode recorded during the EAU Robotic Urology Section meeting 2024, Mr. Ben Challacombe (Guy’s & St Thomas’ MDM Urological Cancer and Clinical Robotics Lead, a UK Robotic Surgery Mentor and Robotic Fellowship Director) spoke to UROONCO RCC Associate Editor Dr. Riccardo Bertolo about robotic resection of renal cell carcinoma recurrence.

Mr. Challacombe provided his strategy on how to plan a treatment if the recurrence takes place after partial nephrectomy. He offered insights into the more appropriate treatment (robotic nephron-sparing approach vs. radical nephrectomy vs. ablation) based on the characteristics of the recurrence.

He also shared his experiences regarding the status of tissues encountered during such surgeries after the patient is exposed to systemic therapy or radiation.

Finally, he shared important insights about the different multi-port and single-port platforms available on the European market, and the choice among them, particularly if such complex surgical interventions must be performed.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, Google Podcasts.

In this episode on "How to install intravesical therapy post-TURBT", Prof. Alexandra Masson-Lecomte (FR) and Prof. Fred Witjes (NL) discuss a case involving a 68-year-old male with a 2 cm bladder tumor at the dome, following a complete TURBT but with a small intraoperative perforation.

They explore key clinical decisions, starting with whether to administer a single postoperative instillation, the choice of drug, and timing considerations. The experts further address how to begin a course of instillations in intermediate-risk patients, including procedural details like nurse or doctor involvement and management of adverse events.

The episode concludes with the management of significant local side effects during BCG therapy and the steps taken when urinary tuberculosis is suspected, highlighting an individualized treatment approach.

Acknowledgment
This activity is supported by an educational grant from our industry partner, with no involvement in the programme or speaker selection.

In 'Episode 1' of the series on "Voices of tomorrow's urologists (ESRU): Journeying through Europe's resident perspectives", Dr. Vital Hevia Palacios and Dr. Alessio Pecoraro discuss "Into the OR: Residents' role in kidney transplants".

This episode takes a look at the valuable contributions urology residents can make during kidney transplant surgeries. Dr. Hevia Palacios and Dr. Pecoraro share their firsthand experiences, shedding light on the challenges and opportunities that come with this vital training. Their conversation provides insights into the evolving role of residents in transplantation, highlighting the importance of hands-on experience in shaping the next generation of urologists.

In "Episode 4" of the series on "What young urologists need to know", segment 3 covers the topic of "Pursuing academic excellence in urology".

In this episode, "Starting your journey in urology research and academics", Prof. Bhaskar Somani (GB) and Dr. Robert Geraghty (GB) discuss the essential steps for newcomers to the field. They share practical advice on how to begin a career in urology research, from identifying research opportunities to finding mentors. The conversation covers the importance of academic publishing and tips for networking in the urology community.

Whether you're a student or a clinician looking to transition into research, this episode offers valuable insights. Tune in to learn how to build a successful academic career in urology.

Welcome to the fourth episode of "Andrology chronicles: Messages for men's health", a podcast series accredited by the EU-ACME programme.

In this final episode, titled "Navigating priapism. Tailored approaches for both ischaemic and non-ischaemic cases", the complexities of diagnosing and managing priapism are explored. Our distinguished speakers, Dr. R. Rees (GB) and Dr. V. Sahdev (GB), provide a comprehensive overview of both ischaemic (low-flow) and non-ischaemic (high-flow) priapism, discussing their distinct etiologies and clinical presentations. They share details on the latest treatment protocols, from emergency interventions to long-term management strategies, ensuring that healthcare professionals are well-equipped to handle these critical situations.

This episode is the last in a series of four. Past episodes include:

The varicocele conundrum. Treatment strategies explored - already released, find it here.
The complex Peyronie’s dilemma. Methods for effective management - already released, find it here.
From investigation to resolution. Tackling advanced erectile dysfunction - already released, find it here.

This series is essential listening for healthcare professionals dedicated to advancing men's health, as well as for patients seeking comprehensive knowledge about their conditions. Tune in to enhance your understanding and stay at the forefront of andrological care.

Upon completion of all four episodes and a post-test questionnaire, listeners will receive 1 European CME credit (ECMEC®) upon completion.Here is the post-test questionnaire for this episode.

Welcome to the third episode of "Andrology chronicles: Messages for men's health", the podcast series accredited by the EU-ACME programme.

In this episode, titled "From investigation to resolution. Tackling advanced erectile dysfunction (ED)", experts Dr. R. Rees (GB) and Dr. V. Sahdev (GB) will take you through a thorough exploration of diagnostic techniques and cutting-edge treatment options. They will examine the underlying causes of advanced ED, ranging from physiological to psychological factors, and discuss the latest advancements in pharmacological treatments, surgical interventions, and lifestyle modifications.

This episode is the third in a series of four. Past or future episodes include:

The varicocele conundrum. Treatment strategies explored - already released, find it here.
The complex Peyronie’s dilemma. Methods for effective management - already released, find it here.
Navigating priapism: Tailored approaches for both ischaemic and non-ischaemic cases - releasing on August 18th.

This series is essential listening for healthcare professionals dedicated to advancing men's health, as well as for patients seeking comprehensive knowledge about their conditions. Tune in to enhance your understanding and stay at the forefront of andrological care.

Upon completion of all four episodes and a post-test questionnaire, listeners will receive 1 European CME credit (ECMEC®) upon completion.Sign in for the post-test questionnaire for this episode.

Welcome to the second episode of "Andrology chronicles: Messages for men's health", a podcast series accredited by the EU-ACME programme.

In this episode, titled "The complex Peyronie’s dilemma: Methods for effective management", we address the challenges and treatment options for Peyronie’s disease, a condition characterised by the development of fibrous scar tissue inside the penis.

Dr. R. Rees (GB) and Dr. V. Sahdev (GB) will guide you through the latest advancements in medical and surgical treatments, as well as innovative non-invasive approaches. They will explore the implications of Peyronie’s disease on sexual health and quality of life, providing a comprehensive understanding of patient management strategies.

This episode is the second in a series of four. Past or future episodes include:

The varicocele conundrum. Treatment strategies explored - already released, find it here.
From investigation to resolution: Tackling advanced erectile dysfunction - releasing on August 11th.
Navigating priapism: Tailored approaches for both ischaemic and non-ischaemic cases - releasing on August 18th.

This series is essential listening for healthcare professionals dedicated to advancing men's health, as well as for patients seeking comprehensive knowledge about their conditions. Tune in to enhance your understanding and stay at the forefront of andrological care.

Upon completion of all four episodes and a post-test questionnaire, listeners will receive 1 European CME credit (ECMEC®) upon completion.

Sign in for the post-test questionnaire for this episode.

Welcome to the first episode of "Andrology chronicles: Messages for men's health", the pioneering podcast series accredited by the EU-ACME programme.

In this debut episode, titled "The varicocele conundrum: Treatment strategies explored", experts discuss the complexities of varicocele, a prevalent yet often misunderstood condition affecting male fertility. Our distinguished speakers, Dr. R. Rees (GB) and Dr. V. Sahdev (GB), provide expert insights into the latest treatment options, ranging from surgical interventions to minimally invasive techniques. Join us as we unravel the challenges in diagnosing varicocele, discuss the efficacy of various treatments, and highlight the impact of timely intervention on patient outcomes.

This episode is the first in a series of four. Future episodes include:

The complex Peyronie’s dilemma: Methods for effective management - releasing on August 4th.
From investigation to resolution: Tackling advanced erectile dysfunction - releasing on August 11th.
Navigating priapism: Tailored approaches for both ischaemic and non-ischaemic cases - releasing on August 18th.

This series is essential listening for healthcare professionals dedicated to advancing men's health, as well as for patients seeking comprehensive knowledge about their conditions. Tune in to enhance your understanding and stay at the forefront of andrological care.

Upon completion of all four episodes and a post-test questionnaire, listeners will receive 1 European CME credit (ECMEC®) upon completion.The post-test questionnaire for this episode can be found via this LINK.

Tune in to 'Episode 3' of the series “What young urologists need to know", segment 3 "Pursuing academic excellence in urology", where Assoc. Prof. Juan Gomez Rivas (ES) and Dr. Nikita Bhatt (GB) discuss Communication skills and how to prepare for presentations.

In this episode, Assoc. Prof. Gomes Rivas and Dr. Bhatt share essential strategies for delivering impactful and engaging presentations, tailored specifically for the urology field.

You will learn how to structure your presentation, master non-verbal cues, and how to handle Q&A sessions with confidence. Both speakers share their personal experiences and insights, offering practical tips to enhance your presentation prowess. Whether you're a novice or an experienced presenter, this episode provides valuable guidance to elevate your academic presentations.

In "Episode 2" of the series on "What young urologists need to know", segment 3 covers the topic of "Pursuing academic excellence in urology".

This discussion covers all aspects of The art of writing urology abstracts: from idea to publication. Experts Dr. Luca Afferi (CH) and Assoc. Prof. Giorgio Ivan Russo (IT) share their tips and strategies for crafting compelling abstracts, from conceptualisation to achieving publication success. Urologists aiming to enhance their academic writing skills and impact the field with their research will find this podcast invaluable.

Dr. Luca Afferi is a uro-oncology fellow at Fundació Puigvert Hospital in Barcelona (ES), and chair of the European Society of Residents in Urology. Assoc. Prof. Giorgio Ivan Russo is a specialist in urology, andrology, infertility, and robotic surgery at the University of Catania (IT).

In "Episode 1" of the series on "What young urologists need to know", segment 3 covers the topic of "Pursuing academic excellence in urology".

In this episode, I want to go on a fellowship: What must I know? , the essentials of pursuing a fellowship are discussed between experts Dr. Alba Sierra Del Rio (ES) and Dr. Yasmin Abu-Ghanem (GB).

Dr. Abu-Ghanem shares her insights on the application process, the importance of choosing the right fellowship, and how to make the most of this transformative experience. Dr. Del Rio, offers a first-hand account of her personal journey, highlighting the challenges and rewards she encountered along the way.

Whether you're considering a fellowship for career advancement, research opportunities, or personal growth, this episode provides valuable advice and inspiration to help you navigate the path ahead. Join us as we explore what you need to know to embark on a successful fellowship journey.

Welcome to another EAUN edition of EAU Podcasts! In this episode, two very experienced nursing professionals, Ms. Therese Kelly (IE) & Ms. Eva Wallace (IE) discuss the complexities of continence issues.

They talk about the need for healthcare professionals to use a holistic approach to address a patient’s concerns. Ms. Kelly and Ms. Wallace offer tips & strategies on conservative management, which is a key component to better patient outcomes.

This EAUN (European Association of Urology Nurses) podcast is part of a series of recordings produced by the Special Interest Group on Continence.

Welcome to the very first EAUN edition of EAU Podcasts. In this episode, Dr. Serena Maruccia (IT), an expert in pelvic floor rehabilitation and the treatment of urinary incontinence, is interviewed by Dr. Stefano Terzoni (IT), a researcher in Nursing at the University of Milan La Statale, and chair of the Special Interest Group on Continence of the EAUN.

Dr. Terzoni and Dr. Maruccia have a frank, open discussion about the very common problem of incontinence and share practical solutions to help patients improve their quality of life (QOL) on a daily basis.

This EAUN (European Association of Urology Nurses) podcast is part of a series of recordings produced by the Special Interest Group on Continence.

In this podcast, UROONCO RCC chief editor Dr. Maria Carmen Mir (ES) talks to Prof. Laurence Albiges (FR) on the abstract she recently presented at ASCO2024 - “Circulating kidney injury molecule-1 (KIM-1) biomarker analysis in IMmotion010: A randomised phase 3 study of adjuvant (adj) atezolizumab (atezo) vs placebo (pbo) in patients with renal cell carcinoma (RCC) at increased risk of recurrence after resection”.

Prof. Albiges details the two parts of the circulating biomarker analysis scheme, part one - biomarker identification/screening; and part two - assessing the association of circulating kidney injury molecule-1 with disease free survival outcomes.

The study results are discussed in detail and Prof. Albiges talks about what research is needed in the future to confirm the utility of circulating serum kidney injury molecule-1 in adjuvant RCC as a non-invasive biomarker.

This podcast features Dr. Bertil Blok (NL), chair of the EAU Guidelines Neuro-Urology panel, and soon to be apppointed as professor of functional neuro-urology at Erasmus University, Rotterdam. He shares details on the latest updates to the EAU Neuro-Urology Guidelines.

Dr. Blok talks about the new recommendations to monitor heart rate and blood pressure during invasive procedures (such as urodynamics, cystoscopy, colonoscopy) in patients with a history of autonomic dysreflexia. He includes the benefits of this, as well as the challenges and limitations.

In this final special edition of episodes recorded live at EAU24, our experts discuss the newest updates to the EAU Guidelines on Male LUTS.

Panel Chair Prof. Jean-Nicolas Cornu and panel member Dr. Manuela Tutolo begin the conversation by discussing the reasoning behind renaming the guideline to Management of Non-Neurogenic Male LUTS. They also dive deeper into new updates, including the addition of chapters on benign prostatic obstruction (BPO), incontinence and overactive bladder (OAB), new assessments for management, and even new concepts for clinical guidance.

Continue to get the latest EAU Guidelines news by downloading the EAU Guidelines App! The app helps to optimise your search with interactive tools to quickly get the answer you need from the best-practice clinical guidelines for urologists. EAU members get full access, and non-members can explore with a 30-day free trial.
Download it here: https://cpms.bbinfotech.com/QRCODE/redirect.php?id=D9Ms80QX

In this EAU podcast, UROONCO chief editor Dr. Giancarlo Marra (IT) interviews Prof. David Penson (US) on the prostate cancer highlights that were recently presented at the American Urological Association Annual Meeting (AUA2024). Prof. Penson is the AUA Secretary General and Chair of Urology Department at Vanderbilt, Nashville, Tennessee.

Their discussion starts with the highlights of the P2 programme session, a new session focused on practice changing paradigm shifting research.

Trials discussed include:
i) HIFI, a non-inferiority, prospective, non-randomised, nationwide study performed in 46 French centres comparing HIFU vs RP;

ii) The Next Generation Trial, a phase II prospective validating paired-cohort trial assessing 18F-PSMA1007 PET/CT and mpMRI for locoregional staging of prostate cancer, with final histopathology as the gold standard comparator;

iii) IN APA-RP: a multicentre, open-label, single-arm, Phase 2 study conducted at 27 US urologic practices, focusing on pts with high risk localised PCa who had undergone RP were treated with apalutamide (240 mg; once daily) and ADT for 12 cycles (1 cycle [28 days]).

Finally, Prof. Penson highlights the session of ongoing clinical trials including studies on neoadjuvant enzalutamide, hood technique versus standard radical prostatectomy and transperineal versus transrectal prostate biopsies.

Dr. Marra was able to do this interview during Prof. Penson's visiting professorship at the Molinette Hospital, University of Turin (IT).

To keep update on prostate cancer developments, go to the UROONCO Prostate Cancer Educational Platform.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates: Apple Podcasts, Spotify, Google Podcasts.

In this special edition of EAU Podcasts, Panel Chair Prof. Philip Cornford (GB) and Vice Chair Prof. Derya Tilki (DE) discuss the latest updates in the EAU Guidelines on Prostate Cancer.

This expert discussion details an update on the issues around nodal involvement in prostate cancer, as well as the management and staging challenges in the 2024 Guidelines. This discussion took place during the EAU Annual Congress (EAU24) in Paris.

In this special edition of EAU Podcasts, panel experts Drs. A. Van Uitert (NL) and Dr. L. A. 't Hoen (NL) met in person at EAU24 to discuss the newest updates to the EAU Guidelines on Paediatric Urology. In their discussion, they cover updates in six chapters, including trauma, congenital lower urinary tract obstruction, fertility preservation, and transitioning to future paediatric care, including minimally invasive sugery.

Welcome to 'Episode 4' of the series “What young urologists need to know", titled "Effective time management for busy urologists: techniques and tools”, where Prof. Francesco Montorsi (IT) and Dr. Laura Mertens (NL) discuss time management tailored specifically for busy urologists.

Dr. Mertens and Prof. Montorsi uncover strategies essential for optimising your workflow. They share invaluable techniques and tools to help you enhance your productivity, from mastering task prioritisation to navigating distractions.

Plus, don't miss out on the interesting stories shared by Prof. Montorsi, offering both wisdom and humour from his wealth of experience.

Tune in now to unlock the secrets to efficient time management which can help you manage your agenda.

In this special edition of EAU Podcasts, experts met in person at the EAU Annual Congress (EAU24) to discuss the newest updates to the EAU Guidelines on muscle-invasive and metastatic bladder cancer (MIBC).

Panel chair Prof. J.A. Witjes led the conversation with co-chair Assoc. Prof. A. Van Der Heijden and panel member Prof. R. Cathomas to cover additions to the local imaging recommendations, restaging and new tools, systemic reviews to the guidelines, and combination therapies.

In this special edition of EAU Podcasts, experts Prof. Paolo Gontero and Prof. Alexandra Masson-Lecomte met in person at the EAU Annual Congress (EAU24) to discuss the newest updates to the EAU Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma (UTUC).

Panel Chairs Prof. Paolo Gontero and Prof. Alexandra Masson-Lecomte cover points of change in the UTUC guidelines, including genetic testing recommendations, risk classifications, and treatment recommendations.

In 'Episode 3' of the series “What young urologists need to know", titled "Mentorship and peer support: Navigating urology together”, Prof. Prokar Dasgupta (GB) and Assoc. Prof. Juan Luis Vásquez (DK) talk about the crucial role of mentorship and peer support in the field of urology.

They discuss how guidance from experienced mentors and collaboration among peers can enhance professional growth, clinical skills, and overall well-being in the challenging realm of urological practice.

Whether it's navigating complex cases or advancing career trajectories, this episode offers invaluable insights for aspiring and established urologists alike, emphasising the power of mentorship and camaraderie in shaping successful medical careers.

Tune in to 'Episode 2' of the series “What young urologists need to know", titled "Academic - clinics balance: How to achieve it?", where Prof. Bhaskar Somani (GB) and Ass. Prof. Giorgio Gandaglia (IT) navigate the delicate equilibrium between academia and clinical practice in urology.In their discussion they share insightful strategies and personal experiences on balancing research commitments with patient care responsibilities. Whether you're a seasoned practitioner or an aspiring academic, this podcast offers invaluable guidance on maintaining balance between advancing medical knowledge and delivering optimal healthcare outcomes.

Tune in to this enriching discussion that promises to inspire and inform!

In 'Episode 1' of the series on "What young urologists need to know", segment 2 covers the topic of "Balancing the life of a young urologist". Dr. Thomas Tailly (BE) and Dr. Michiel Sedelaar (NL) offer a comprehensive exploration of the age-old question: Is it truly possible to strike a balance between work and well-being?

Dr. Tailly and Dr. Sedelaar delve into the intricate interplay between work and well-being. Through their insightful discussion and evidence-based insights, you can gain ideas on how to achieve a harmonious balance between professional commitments and personal fulfilment. Tune in to learn some practical strategies to cope in today's fast-paced world of urology.

In 'Episode 3', the final of the series on "Metastatic renal cell carcinoma", Dr. Andrea Mari (IT) talks with Dr. Chiara Ciccarese (IT) from the Medical Oncology Unit at Fondazione Policlinico Universitario A. Gemelli IRCCS, in Rome. Together they have an in-depth discussion on "Beyond first-line treatment strategies for metastatic renal cell carcinoma".

Dr. Mari and Dr. Ciccarese delve into recent advancements in managing mRCC, including therapeutic options, and their impact on patient care and outcomes. From targeted therapies to immunotherapies, they offer a comprehensive exploration of the evolving treatment landscape.

Tune in to this engaging and informative conversation with two distinguished experts at the forefront of cancer research and treatment.

In 'Episode 2' of the series on "Metastatic renal cell carcinoma", Dr. Andrea Mari (IT) talks to Dr. Laura Marandino (GB) about "The first-line treatment strategies for metastatic renal cell carcinoma".

Dr. Andrea Mari and Dr. Laura Marandino unravel the complexities of mRCC management, exploring the latest advancements, therapeutic options, and their implications for patient care. From targeted therapies to immunotherapies, they provide a comprehensive overview of the evolving treatment landscape.

Tune in as we navigate through this insightful conversation with two distinguished guests at the forefront of cancer research and treatment.

This podcast episode was recorded before ASCO GU 2024. Please note that information discussed may not reflect updates from the conference. We encourage listeners to verify the latest information independently.

UROONCO PCa associate editor Dr. Constance Thibault (FR) talks to Prof. Christophe Hennequin from Saint-Louis Hospital, France about the GETUG-AFU 18 trial results he presented at ASCO GU24 in San Francisco.

Prof. Hennequin shares details on the design of the study, followed by the trial results of long-term dose escalation (80 vs 70Gy) combined with long-term androgen deprivation in high-risk prostate cancer.

For more details on this study, you can read this abstract on the UROONCO Prostate Cancer educational platform.

In 'Episode 1' of a series on "Metastatic renal cell carcinoma", Assist. Prof. Andrea Mari (IT) and Prof. Ketan Badani (US) discuss "The role of cytoreductive nephrectomy for metastatic renal cell carcinoma ".

Assist. Prof. Andrea Mari and Prof. Ketan Badani delve into the pivotal role of cytoreductive nephrectomy in the management of metastatic renal cell carcinoma (mRCC). They talk about the rationale behind this surgical intervention, its impact on patient outcomes, and the evolving landscape of treatment strategies in advanced kidney cancer.

Whether you're a healthcare professional or someone seeking insights into cutting-edge cancer therapies, this discussion promises to illuminate the complexities of renal cell carcinoma management.

In this podcast, UROONCO RCC chief editor Dr. Carmen Mir (ES) interviews Prof. Michael Hofman from the Peter MacCallum Cancer Centre, Australia, on the results of his study “First-in-human safety, imaging and dosimetry of [68Ga]Ga-DPI-4452, a novel CA IX-targeting peptide, in patients with clear cell renal cell carcinoma (ccRCC)”.

Prof. Hofman discusses the data he presented at ASCO GU24 in San Francisco and suggests that these first-in-human findings with radiolabelled DPI-4452 are encouraging for the subsequent evaluation of treatment with [177Lu]Lu-DPI-4452.

[68Ga]Ga-DPI-4452 provides exceptional images in patients with ccRCC without clinically significant toxicity. Very high SUVs and tumour-to-background ratios suggest potential for use in both diagnostics and patient selection for therapy. The tumour retention and rapid elimination support potential of [177Lu]Lu-DPI-4452 radioligand therapy.

For more details on this study, you can read the abstract on the UROONCO Kidney Cancer educational platform.

In this podcast, UROONCO RCC chief editor Dr. Carmen Mir interviews Prof. Nizar Tannir from the University of Texas, MD Anderson Cancer Center, USA, on the long-term follow-up data from the phase 3 CheckMate 214 trial: Nivolumab plus ipilimumab (NIVO+IPI) vs sunitinib (SUN) for first-line treatment of advanced renal cell carcinoma (aRCC).

Prof. Tannir summarises the history and stability of the Checkmate 214 trial results over the last 8 years, before discussing the latest data from his presentation at ASCO GU24 in San Francisco.

For more details on this trail, you can read the abstract on the UROONCO Kidney Cancer educational platform.

In this podcast interview live from ASCO GU24 in San Francisco, UROONCO PCa associate editor Dr. Constance Thibault (FR) talks to medical oncologist Dr. Kim Chi from the University of British Columbia, Canada, about the CONTACT-2 trial. This randomised phase 3 trial aimed to evaluate the efficacy of cabozantinib + atezolizumab vs. second novel hormonal therapy in patients with metastatic castration-resistant prostate cancer (mCRPC).

Dr. Chi shares his interpretation of the study design and the main outcomes, including the safety profile. During the interview, Dr. Chi also explains why he does not believe it will become the new standard of care for patients with mCRPC, and details the more preferrable options available for this patient population.

For more details on this trial, you can read the abstract on the UROONCO Prostate Cancer educational platform.

In this podcast, UROONCO RCC chief editor Dr. Carmen Mir (ES) interviews Assoc. Prof. Pedro Barata from University Hospitals Seidman Cancer Center, USA, about the results of two adjuvant RCC studies: KEYNOTE-564; and CheckMate-914.

Assoc. Prof. Barata explains the positive trial results of KEYNOTE-564, which is the first time there has been an overall survival advantage with a PD-1 inhibitor in the pure adjuvant setting in RCC. These results support adjuvant pembrolizumab as a standard of care after surgery.

CheckMate-914 explored adjuvant nivolumab monotherapy versus placebo for patients with high-risk localised RCC post-nephrectomy. The trial had negative results as it did not meet its primary endpoint of disease-free survival improvement.

In an expert analysis at ASCO GU24, Assoc. Prof. Barata presented on adjuvant treatment for RCC and the strategies on how to optimise patient selection for the new standard of care.

For more details on these trials, you can also read the abstract on KEYNOTE-564 and the abstract on CheckMate-914 on the UROONCO Kidney Cancer educational platform.

In this podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) interviews medical oncologist Dr. Andrea Apolo from the National Cancer Institute, USA, on the results of the AMBASSADOR study, which she presented at ASCO GU24.

Dr. Apolo shares details on the rationale of the AMBASSADOR study: An open-label, randomised, phase III trial, evaluating the efficacy and safety of pembrolizumab as an adjuvant treatment in muscle-invasive and locally advanced urothelial carcinoma (MIUC).

Dr. Apolo discusses the positive second interim data for disease-free survival (DFS), with a medium DFS with adjuvant pembrolizumab of 29 months vs. 14 months in the observation arm. Based on these findings, Dr. Apolo stated that pembrolizumab is active and should be considered as a therapy for patients in the adjuvant setting.

For more details on this study, you can read this abstract on the UROONCO Bladder Cancer educational platform.

In this podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) interviews Dr. Srikala Sridhar (CA), about her abstract she recently presented at ESMO 2023, PET-MUSE: “Impact of positron emission tomography (PET) imaging on staging of muscle-invasive bladder cancer (MIBC)”.

Dr. Sridhar shares details on the rationale and design of the study, as well as some interesting results.

For more details on this study, you can read this abstract on the UROONCO Bladder Cancer educational platform.

In this edition, Dr. Aisling Nic an Riogh (IE), a member of the EAU Guidelines panel for Non-neurogenic female LUTS, discusses bladder outlet obstruction (BOO) in women.

Dr. Nic an Riogh defines bladder outlet obstruction, its prevalence, and the various symptoms. She further explains that BOO can be divided into two main groups, anatomical (physical or mechanical), and functional (non-anatomical, non-urogenic). It is diagnosed via urodynamics, and Dr. Nic an Riogh discusses the various tests available.

Lastly, the guidelines for conservative treatment and surgical options are discussed in detail.

In this podcast, UROONCO RCC board members, chief editor Dr. Carmen Mir (ES), and associate editors Dr. Riccardo Bertolo (IT) and Dr. Teele Kuusk (GB), discuss the progress made in the field of kidney cancer during 2023, and what is anticipated for 2024.

Some topics discussed include the game-changing ZIRCON trial, OpeRa trial, and 3D models in PN and single-port RPN, as well as SBRT – FASTRACK II. Adjuvant IO, first-line mRCC treatments (KEYNOTE-426), and RN is also reviewed.

The main WHO classification changes are highlighted, as well as the classification changes that are expected in 2024. This podcast concludes with a summary of the RCC trials to look forward to in the coming year.

In 'Episode 4' of the series "What do young urologists need to know," 'Segment 1' covers the topic of "Navigating the transition from residency to professional urology practice." Assoc. Prof. Emre Şener (TR) discusses networking and building professional relationships in urology with Dr. Amelia Pietropaolo (GB).

Assoc. Prof. Şener and Dr. Pietropaolo delve into the critical aspects of establishing robust connections within the urology field. They emphasise the significance of networking for young professionals, highlighting strategies to initiate and nurture meaningful relationships with mentors, colleagues, and industry peers. The episode provides actionable tips on leveraging social media, attending conferences, and engaging in collaborative projects to expand one's professional network.

Ultimately, the episode aims to empower young urologists with the skills needed to forge impactful connections, fostering career growth and knowledge-exchange within the urology community.

This is 'Episode 3' of the podcast series "What do young urologists need to know," 'Segment 1': "Navigating the transition from residency to professional urology practice." Dr. Elena Seguí-Moya (GB) converses with Prof. Sabine Brookman-May (US) about preparing for a job interview.

The discussion highlights essential steps and strategies for excelling in a job interview within the specialised field of urology, emphasising the importance of showcasing clinical skills or research experience. Additionally, the episode offers valuable tips on effectively communicating one's passion for the field and aligning personal goals with the prospective employer's vision, ensuring a successful and promising start to a urology career.

In 'Episode 2' of the series on "What young urologists need to know," segment 1 covers the topic of "Navigating the transition from residency to professional urology practice." Dr. Bhavan Prasad Rai (GB) and Dr. Guido Kamphuis (NL) delve into the aspects of preparing and maintaining an effective CV.

Dr. Rai and Dr. Kamphuis talk about how your CV should highlight relevant experiences and achievements, exploring the key elements that make a standout CV in the competitive field of urology. They emphasise the importance of tailoring your CV to reflect your career aspirations, including research, clinical, and academic pursuits specific to urology.

Additionally, Dr. Rai and Dr. Kamphuis touch upon the significance of regularly updating your CV to reflect ongoing professional development, certifications, and new skills in this rapidly evolving field.

Tune in for expert insights and practical tips that will help young urologists present themselves effectively on paper and pave the way for a successful career trajectory.

In 'Episode 1' of the series on "What young urologists need to know," segment 1 covers the topic of "Navigating the transition from residency to professional urology practice." Assoc. Prof. Veeru Kasivisvanathan (GB) and Ms. María Pilar Moreno-Fontela (ES) discuss the significant transition from residency to independent practice in this episode titled: "My residency is finished: how will my life change?"

Assoc. Prof. Kasivisvanathan and Ms. Moreno-Fontela delve into the challenges and adjustments that come with newfound autonomy, such as managing patient loads, navigating administrative tasks and adapting to a different work-life balance.

The episode sheds light on the shifts experienced by these urologists, offering insights and advice on coping mechanisms, time management, and building a supportive network in the field. Additionally, it explores strategies for continual learning and growth as they embark on this new phase of their medical careers.

In this podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks with Prof. James Catto (GB) about the THOR-2 cohort 1 study: Results of erdafitinib (ERDA) vs intravesical chemotherapy (chemo) in patients with high-risk non-muscle-invasive bladder cancer (NMIBC) with select fibroblast growth factor receptor alterations (FGFRALT) who received prior bacillus calmette-guérin (BCG) treatment.

Prof. Catto shares details on the rationale and design of the THOR-2 cohort 1 study, the results he presented at ESMO 2023, and some important take-home messages.

For more details on this study, you can read this abstract on the UROONCO Bladder Cancer educational platform.

In this podcast, Dr. Neeraj Agarwal (US), presidential endowed chair of cancer research at the Huntsman Cancer Institute, University of Utah, shares the results of the LITESPARK-013 Phase 2 trial - "Safety and efficacy of two doses of belzutifan in patients with advanced renal cell carcinoma", that he presented at ESMO 2023.

Firstly, Dr. Agarwal shares the rationale of the study, which compared belzutifan 200mg and 120mg doses in patients with advanced clear cell RCC that progressed on anti-PD-1/L1 therapy to evaluate the safety and efficacy of these two doses in a larger, randomised trial.

Dr. Agarwal said that there was no difference in efficacy outcomes of belzutifan 200 mg and 120 mg orally once daily. Progression-free survival and overall survival were similar, as were the safety profiles between the two doses.

But, according to Dr. Neeraj, when they took a deep dive into the belzutifan 200mg once daily dose, it was associated with a higher rate of overall dose modifications and drug discontinuation. Based on these results, he concluded that belzutifan 120mg once daily dose in patients with clear cell RCC should remain the dose.

In this podcast, UROONCO RCC associate editor Dr. Teele Kuusk (GB) talks with Prof. Roberto Iacovelli (IT), Gostino Gemelli University Polyclinic, Rome, about the abstract he presented at ESMO 2023, "The TIDE-A study: Phase II study of avelumab (Ave) plus intermittent axitinib in previously untreated patients with metastatic renal cell carcinoma".

Prof. Iacovelli shares details on the TIDE-A study, the first study demonstrating the potential benefits of VEGFR-TKI interruption combined with immunotherapy. Results showed decreased treatment-related toxicity and delayed tumour progression in mRCC patients. The safety of the combination of avelumab and axitinib in mRCC patients was also promising, and he suggests that future investigations in a randomised trial would be worthwhile.

In this podcast, UROONCO RCC associate editor Dr. Teele Kuusk (GB) talks with medical oncologist Prof. Laurence Albiges (FR), Head of the Department of Oncology at Gustave Roussy, about her abstract: Belzutifan versus everolimus in participants with previously treated advanced clear cell renal cell carcinoma (ccRCC): Randomised open-label phase III LITESPARK-005 study.

Prof. Albiges discusses the study results she presented at ESMO 2023. LITESPARK-005 established HIF-2a inhibition as a novel therapeutic mechanism of action in advanced clear cell RCC. Belzutifan demonstrated a statistically significant improvement in progression-free survival (PFS) and objective response rate versus everolimus.

LITESPARK-005 is the first positive phase 3 study in patients with advanced kidney cancer following immune checkpoint and anti-angiogenic therapies.

Prof. Albiges also answers a question about why everolimus was used as a comparator in this trial. Looking at the future, she shares her vision of how Belzutifan (the new HIF inhibitor) can be used for metastatic kidney cancer patients.

Lastly, Prof. Albiges talks about what trials are ongoing that will position Belzutifan on the treatment line. Belzutifan is currently being studied in combination in second-line, first-line, and adjuvant settings in phase 3 studies.

In this podcast from ESMO 2023, UROONCO BCa associate editor Dr. Laura Mertens (NL) talks with Dr. Michiel Van Der Heijden (NL) on his abstract “Nivolumab plus gemcitabine-cisplatin versus gemcitabine-cisplatin alone for previously untreated unresectable or metastatic urothelial carcinoma: results from the phase 3 CheckMate 901 trial”.

Dr. Van Der Heijden shares details on the design of the trial and the late-breaking results that he presented at ESMO 2023.

Primary endpoints were met with overall survival (OS) and progression-free survival (PFS). Dr. Van Der Heijden also talks about the secondary endpoints, such as complete response rate, durability.

For more details on this trial, you can read this abstract on the UROONCO Bladder Cancer educational platform.

In this special podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks with Prof. Thomas Powles (GB) about the positive results of the EV-302/KEYNOTE-A39 trial that were announced at ESMO 2023.

Prof. Powles shares details on the rationale and design of the EV-302/KEYNOTE-A39 study: an open-label, randomised, controlled, phase 3 study evaluating enfortumab vedotin in combination with pembrolizumab (EV+P) versus chemotherapy in patients with previously untreated locally advanced metastatic urothelial carcinoma (la/mUC).

The dual endpoints of this trial are overall survival (OS) and progression-free survival (PFS) per RECIST (response evaluation criteria in solid tumours) v 1.1 by blinded independent central review (BICR).

Prof. Powles: "The topline results from the EV-302/KEYNOTE-A39 trial are encouraging for patients with advanced-stage urothelial cancer, which is aggressive and associated with devastating outcomes."

For more details on this study, you can read the abstract on the UROONCO Bladder Cancer educational platform.

In 'Episode 4' of the special podcast series on "Uro-oncologic surgery driven by new technologies", Prof. Ricardo Autorino (IT) talks to expert Assoc. Prof. Giovanni Enrico Cacciamani (US) about Artificial intelligence application for urologic cancer detection and classification.Artificial Intelligence (AI) has revolutionised urologic cancer detection by leveraging principles from computer science, machine learning and deep learning. In this context, AI serves as a powerful tool to improve the accuracy and efficiency of cancer diagnosis and treatment.

Assoc. Prof. Cacciamani shares his knowledge how computer science forms the foundation of AI algorithms, enabling the processing and analysis of vast datasets, including medical images and patient records. Machine learning techniques, a subset of AI, are applied to these datasets to create predictive models that can identify patterns and anomalies within patient data. Deep learning, a specialised branch of machine learning, excels in image recognition tasks and has been instrumental in the interpretation of medical images like CT scans, MRI scans, and histopathological slides.

By implementing AI in urologic cancer detection, healthcare professionals can achieve faster and more accurate diagnosis, early cancer detection, and personalised treatment recommendations. AI systems can assist in the identification of tumours, tracking their growth over time, and predicting patient outcomes. This integration of AI technologies enhances the quality of patient care, potentially leading to better survival rates and improved overall well-being for individuals with urologic cancers.

This podcast was produced in collaboration with the YAU Urotechnology group.

In 'Episode 3' of the podcast series on "Uro-oncologic surgery driven by new technologies", Prof. Ricardo Autorino (IT) talks to expert Dr. Inés Rivero Belenchón (ES) about 3D models for kidney cancer with caval thrombous.

3D models are proving invaluable in addressing kidney cancer cases involving caval thrombosis, where the tumour extends into the vena cava. Dr. Rivero Belenchón discusses how these models, generated from advanced imaging, offer precise visualisations of the tumour's position and size within the blood vessels. Surgeons use these models to plan intricate procedures that remove the tumour while minimising damage to vital vessels, and they can simulate surgeries beforehand for better outcomes.

Dr. Rivero Belenchón points out that interdisciplinary collaboration among medical experts is also enhanced, leading to more personalised and effective treatment strategies. In essence, 3D models greatly improve surgical planning and patient care for kidney cancer with caval thrombosis.

This podcast is made in collaboration with the YAU Urotechnology group.

In this podcast, UROONCO PCa associate editor Dr. Giancarlo Marra (IT) talks to Prof. Hashim Ahmed (GB) after his presentation at UROonco23 on focal therapy for low- or intermediate-risk prostate cancer.

They discuss the main reasons for the change in the new guidelines this year. Prof. Ahmed details the dangers of rapid dissemination. He also shares his expert opinion on how he positions focal therapy within the context of the PROTECT trial results. He concludes with information on other recent focal trials, such as the FARP trial.

In 'Episode 2' of this special podcast series on "Uro-oncologic surgery driven by new technologies", Prof. Ricardo Autorino (IT) talks to expert Ass. Prof. Daniele Amparore (IT) about vascular perfusion 3D models and augmented reality for kidney cancer surgery.

Vascular perfusion 3D models and augmented reality (AR) are revolutionising kidney cancer surgery. These technologies provide surgeons with detailed 3D representations of patients' kidneys and their blood vessels. By incorporating colour-coded perfusion data, surgeons can identify and preserve vital vessels while resecting the tumour.

Ass. Prof. Amparore discusses how AR takes this further by overlaying these models onto the surgeon's view during the operation, enhancing precision in locating tumour boundaries and critical vessels. This integration enhances surgical planning, reduces risks, and improves postoperative outcomes, particularly in partial nephrectomies. Beyond kidney surgery, these advancements hold potential for transforming complex procedures across medical specialties.

This podcast is made in collaboration with the YAU Urotechnology group.

In this podcast, UROONCO RCC associate editor Dr. Riccardo Bertolo (IT) interviews a recognised world leader in the research and treatment of kidney cancer, Prof. Ketan Badani (US), from Mount Sinai Hospital. He answers questions on robot-assisted partial nephrectomy (RAPN) after his live surgery session at ERUS23 in Florence, Italy.

Prof. Badani elaborates on the concept of complexity in RAPN.

Another point in the discussion is the decision algorithm in counselling the patient to multi-port vs. single port robotics.

Finally, Prof. Badani also shares some personal experience on training for the future of robotic surgery and how single-port can teach surgeons how to operate more autonomously when operating multi-port, which has historically relied on a significant bedside team/assistance.

This is 'Episode 1' of a new podcast series on "Uro-oncologic surgery driven by new technologies." Prof. Ricardo Autorino (IT) talks to expert Dr. Enrico Checcucci (IT) about 3D models and augmented reality for prostate cancer surgery.

In the realm of prostate cancer surgery, 3D models and augmented reality (AR) are emerging as transformative technologies. Surgeons are utilising 3D models generated from patient imaging data (mp-MRI in particular for prostate cancer) to create precise visualisations of the prostate and its surrounding structures. These models offer detailed insights into tumour location, aiding in surgical planning and decision-making.

AR takes this a step further by overlaying virtual information onto the surgeon's field of view during the procedure. This real-time augmentation provides surgeons with vital data, such as tumour boundaries and critical blood vessels, enhancing surgical accuracy and reducing the risk of complications.

Ultimately, the integration of 3D models and AR in prostate cancer surgery holds the potential to revolutionise the way surgeries are planned and executed, leading to improved patient outcomes and more precise interventions. Lastly, the advent of artificial intelligence and its integration with AR platforms will allow for the improvement of the precision of the overlapping with more dynamic assistance for the surgeon.

This podcast is made in collaboration with the YAU Urotechnology group.

This is 'Episode 4' of the special podcast series on "Preoperative, intraoperative and postoperative new technological tools for urologists". Assoc. Prof. Juan Gómez Rivas (ES) talks to expert Dr. Karl-Friedrich Kowalewski (DE) on laparoscopy procedures and the emergence of advanced robotic platforms.

Over the years laparoscopy has become the standard for various interventions, such as gallbladder removal, appendectomy and certain gynaecological procedures. However, recent advancements in robotic surgical platforms have revolutionised the field, offering enhanced precision, dexterity, and 3D visualisation for complex surgeries.

Dr. Kowalewski analyses the benefits and limitations of both laparoscopic and robotic approaches. This information can help with decision-making to determine the most suitable surgical method for specific interventions based on patient characteristics and procedure complexity.

This podcast is made in collaboration with the YAU Urotechnology group.

In this third episode of the special podcast series on "Preoperative, intraoperative and postoperative new technological tools for urologists", Assoc. Prof. Juan Gómez Rivas (ES) talks to Assoc. Prof. Stefano Puliatti (IT) from the University Hospital of Modena, about new technology for surgical training.

Assoc. Prof. Puliatti shares details of psychologist Prof. Anthony Gallagher's development of the proficiency-based progression (PBP) methodology for surgical training, whereby metrics for a single specific procedure are followed (including critical errors and steps for standardised procedures). Once the training in the lab is mastered, trainees can progress.

New technologies that are really game-changing are recordings and sharing platforms so you can find surgeries done by experts and learn from these, as well as watching your own recordings to look for mistakes. Also, virtual or augmented reality, and 3D printing models, which help with reconstruction and surgical planning. 5G and telementoring will allow for communications from experts via real-time. Devices such as Google glasses may also prove useful in the future.

Assoc. Prof. Puliatti elaborates on the expense and accessibility of training with these new technologies, and some potential solutions.

This podcast is made in collaboration with the YAU Urotechnology group.

In this second episode of the special podcast series on "Preoperative, intraoperative and postoperative new technological tools for urologists", Assoc. Prof. Juan Gómez Rivas (ES) talks to the distinguished Prof. Dmitry Enikeev (IL) about new lasers that are shaping the future of endourology.

Prof. Enikeev elaborates on how lasers work, and the different types of lasers (thulium, holmium, green light). He shares details on usage, settings and the important aspects of distance of incision and speed.

Cutting-edge lasers in endourology have significantly improved the management of kidney stones, bladder tumours and other urological disorders. They allow for safer and faster procedures, reducing patient recovery time and hospital stays. Additionally, the improved energy delivery systems enable better control and accuracy during surgery, leading to fewer complications and improved outcomes.

This podcast is made in collaboration with the YAU Urotechnology group.

This is 'Episode 1' of a new podcast series on "Preoperative, intraoperative and postoperative new technological tools for urologists." Assoc. Prof. Juan Gómez Rivas (ES) talks to expert Dr. Severin Rodler (DE) about the role of telemedicine and applications for the management of cancer patients.

Telemedicine and healthcare applications have revolutionised patient management by offering remote healthcare services and personalised tools for patients. Dr. Rodler discusses the benefits of these innovations such as increased accessibility to healthcare, as well as reduced hospital visits, cost savings, and empowering patients to take a proactive role in monitoring and managing their health.

Nevertheless, Dr. Rodler shares details the significant challenges to consider also. These include the limited capability for physical examinations, accuracy of diagnoses, potential for misdiagnosis, improper treatment, technological barriers, and privacy issues.

When looking at the future of telemedicine, Dr. Rodler expresses the importance of guidelines, the need for level one evidence in a remote setting, and the formation of a secure data infrastructure.

This podcast is made in collaboration with the YAU Urotechnology Working Group.

This podcast features Prof. Gernot Bonkat (CH) and Dr. Kathrin Bausch (CH) discussing the addition of a new chapter on urogenital tuberculosis to the EAU Guidelines on urological infections.

They explain that the lack of knowledge among urologists about tuberculosis, particularly genital tuberculosis, was a reason for adding the new chapter.

Tuberculosis is an ancient bacterial disease affecting not only the lungs but also other organs, including the urogenital tract. Diagnosis of urogenital tuberculosis is often delayed due to the disease's mixed and non-specific symptoms, and people may mistake it for a urinary tract infection (UTI).

Prof. Bonkat and Dr. Kathrin discuss diagnostic options specifically for bladder and kidney tuberculosis, such as urine investigations, microscopy, and PCR - which allows for faster diagnosis and resistance testing (but is not affordable for everyone).

Treatment recommendations are also discussed, as well as taking a look into the future of vaccination possibilities, and drug resistance.

Prof. Gernot Bonkat (CH) is chair of the EAU Guidelines urological infections panel and Dr. Kathrin Bausch (CH) is member of the same panel.

In this podcast, Dr. Kristin Zimmermann (DE) and Dr. Felix Campos-Juanatey (ES) discuss a grade 4 renal trauma case in a young woman who was kicked by a horse. They talk through the decision-making process for her diagnosis, treatment and follow-up, as well as the complications encounted.

Diagnostics included FAST (Focused Assessment Sonography in Trauma), and
then the American Association of Surgery of Trauma classification (AAST) was applied for clinical decision-making and planning further management. The patient underwent a CT scan, which revealed a blunt grade 4 trauma with urinary extravasation.

The conservative approach involved bed rest, thrombo-prophylaxis, and a long course of antibiotics due to the risk of infection, but the patient experienced a drop in haemoglobin levels. This prompted more investigations and a repeat CT scan, which revealed active bleeding.

Subsequently, an embolisation procedure successfully stopped the bleeding. The patient recovered well, and after monitoring her condition, she was discharged with pain medication. Follow-up appointments and tests were planned to assess her long-term recovery.

Dr. Zimmermann and Dr. Campos-Juanatey are members of the EAU Guidelines panel on Urological Trauma.

In this podcast, Dr. Paolo Capogrosso and Dr. Marco Falcone talk about the new chapter in the sexual and reproductive EAU Guidelines on penile abnormalities and penis dysmorphophobia.

With an increase in surgery requests, Dr. Capogrosso and Dr. Falcone talk about the lack of evidence in this field of urology, hence most surgical procedures for penile girth or length enhancement are experimental and should be approached with caution. The aim of the new guidelines is to provide evidence-based treatment to patients with penile size complaints and increase awareness of these conditions.

They emphasise the importance of taking a full medical history and conducting precise penile measurements.

Dr. Capogrosso also talks about the new section on male contraception and a systematic review on vasectomy and vasectomy reversal that they are currently working on, which will provide evidence-based treatments.

Dr. Paolo Capogrosso (IT) and Dr. Marco Falcone (IT) are both members of the EAU Guidelines Sexual and Reproductive Health panel.

In this roundtable discussion, Prof. Florian Wagenlehner, Dr. Zafer Tandoğdu, and Dr. Anne Ackerman talk about the challenges of infections in urology, specifically related to antimicrobial resistance.

Factors such as ageing population and over-medicalisation are identified as possible causes of the increase in mortality rates for urosepsis and other antimicrobial-resistant infections.

The importance of appropriate microbiological workup and non-antibiotic treatments to better support patients is discussed, as well as pitfalls in diagnosing infections in the elderly population, such as the prevalence of bacteriuria. The fear of bad outcomes for patients drives the overuse of antibiotics, despite the risk of antimicrobial resistance.

Prof. Dr. Florian Wagenlehner (DE) is member of the EAU Guidelines panel on Urological Infections, Dr. Z. Tandoğdu (GB) is chair of the EAU Section of Infections in Urology, and Dr. Anna Ackerman (US) is a urologist at Cedars-Sinai Medical Centre in Los Angeles, California.

In this podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks to Dr. Arlene O. Siefker-Radtke (US) from the Depart. of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston. She answers questions about the recent ASCO23 presentations on metastatic urothelial cancer (mUC), where new results of the phase II Norse study, and the phase III THOR study were shared.

Phase II Norse study:
Dr. Siefker-Radtke elaborates on the study rational and pleasing results of the phase II Norse study: Erdafitinib (erda) vs erda plus cetrelimab (erda+CET) for patients with metastatic urothelial carcinoma (mUC) and fibroblast growth factor receptor alterations (FGFRa). Single agent erdafitinib had an objective response rate of around 45%. The combination of erdafitinib and cetrelimab had an objective response rate of around 55%. Single agent erdafitinib had a progression-free survival (PFS) of around 5.5 months, and the combination arm had a median survival of around 11 months. The median overall survival with erdafitinib alone was around 16 months, whereas the combination had a median overall survival of around 20.8 months.

Phase III THOR study:Dr. Siefkerdiscusses the phase III results whereby erda significantly improved overall and PFS, as well as overall response rate, compared with chemotherapy, in patients with advanced or mUC and FGFR alteration who already had been treated with a PD-(L)1 inhibitor.

For more details on these studies, you can read the abstracts on the UROONCO educational platform - phase II Norse, phase III THOR.

In this podcast, Prof. Igor Tsaur (DE), chief editor of the UROONCO PCa editorial board talks with Dr. Craig Jones (GB), from Salford Royal and Christie Hospitals, about his recent presentation at AUA2023, "Clinical fracture incidence in metastatic hormone-sensitive prostate cancer (mHSPC) and risk-reduction following addition of zoledronic acid to androgen deprivation therapy (ADT) with or without docetaxel (Doc): Long-term results of two phase 3 trials from the STAMPEDE platform protocol."

Mr. Craig Jones answers the following questions:

Could you distinguish osteoporotic from pathological fractures in your analysis based on routinely-collected healthcare data? Would a higher rate of pathological fractures explain the higher incidence of clinical fracture events in the M1 as compared to M0 subgroup?
Are there data on symptomatic skeletal events as opposed to skeletal related events as a more relevant endpoint for health related quality of life?
Risk of osteoporosis when utilising ADT+Docetaxel as compared to ADT+NHA?
Denosumab outperformed Zoledronic acid for prevention of SRE in mCRPC. How would you compare both drugs in mHSPC?

To keep up to date with prostate cancer developments, you can also visit our educational platform, UROONCO Prostate Cancer.

In this podcast, Prof. Igor Tsaur (DE), chief editor of the UROONCO PCa editorial board talks with Dr. Antony Pellegrino (IT) about his recent presentation at AUA 2023 on positive surgical margins.

The impact of multiparametric MRI on surgical approach during radical prostatectomy (RP) and on oncological outcomes after surgery is still controversial.

Dr. Pellegrino discusses the results of the topographic single centre study to predict the site of positive surgical margins (PSM) based on the site of the index lesion at multiparametric MRI.

To keep up to date with prostate cancer developments, you can also visit our educational platform, UROONCO Prostate Cancer.

In this podcast, Dr. Riccardo Bertolo (IT), associate editor of the UROONCO kidney cancer editorial board talks to Prof. Jihad Kaouk (US) from the Glickman Urological and Kidney Institute, Cleveland Ohio. Prof. Kaouk answers questions about his recent AUA2023 presentation, "Single port robotic urologic surgery: where are we today and where are we headed?"

The discussion includes details on the pioneering of new technologies, specifically the novel single-port robotic platform. Prof. Kaouk talks about the adoption of its use into daily practice and what it's value is, with many advantages far beyond cosmetic appearance.

Prof. Kaouk shares a summary of the technical modifications his team had to deal with in regards to resection and renorrhaphy techniques during partial nephrectomy, such as modified anterior access for retroperitoneal approach to partial nephrectomy.

Lastly, what are the plans for the single-port platform in Europe?

In this podcast, Prof. Igor Tsaur (DE), chief editor of the UROONCO PCa editorial board talks with Dr. Marcio Covas Moschovas (US) about his abstract presentation at AUA2023, “Simultaneous hernia repair following robotic-assisted radical prostatectomy is safe with low rates of mesh-related complications”.

Dr. Moschovas answers questions about the study design and the data presented. He compared 244 patients who underwent RARP with concomitant hernia repair (inguinal, umbilical, and ventral) and mesh placement, with 244 patients from 6,275 RARPs operated on the same period without hernia repair. He also shares details on what kind of mesh was used in different cases, such as 3D and pro-grip.

To keep up to date with prostate cancer developments, you can also visit our educational platform, UROONCO Prostate Cancer.

In this podcast, Dr. Maria Carmen Mir Maresma (ES), chief editor of the UROONCO RCC editorial board talks to key opinion leader Prof. Alexander Kutikov (US) from Fox Chase Cancer Centre, Philadelphia.

Prof. Kutikov shares details from his recent AUA2023 presentation in Chicago on the surgical complications associated with robotic partial nephrectomy (RPN).

He discusses the four major categories of complications of RPN which include vascular complications (haemorrhage, renal AV fistula/renal artery pseudoaneurysm), urine leak, injury to surrounding structures, and non-RO resection.

As one of the pioneers on complexity measurements for renal masses, Prof. Kutikov talks about the evolution of new technologies and how that will correlate with complications assessment.

He concludes with an update on machine learning and his opinion on how artificial intelligence will assist in preventing surgical complications during RPN.

To keep up to date with kidney cancer developments, you can also visit our educational platform, UROONCO RCC.

In this podcast, UROONCO BCa chief editor Dr. Benjamin Pradere (FR) talks to Prof. Siamak Daneshmand (US) from the Keck School of Medicine, University of Southern California. Prof. Daneshmand answers questions about the SunRISe-1 trial, which he presented at the 'late-breaking oncology abstract session' during AUA2023.

He discusses the study design, and delivers preliminary results from SunRISe-1 in patients with BCG (Bacillus Calmette-Guérin) unresponsive high-risk non–muscle-invasive bladder cancer receiving TAR-200 in combination with cetrelimab, TAR-200, or cetrelimab alone.

The promising findings from TAR-200 monotherapy showed an overall complete response rate of 73% in patients with high-risk non-muscle-invasive bladder cancer (NMIBC) who were unresponsive to BCG. Prof. Daneshmand says the treatment was well-tolerated. Additionally, cetrelimab monotherapy demonstrated safety and efficacy profiles consistent with other anti-PD-L1 treatments in this disease setting.

In this podcast Prof. Nicolas Mottet and Prof. Phil Cornford discuss the 2023 EAU Guidelines for prostate cancer. The new recommendation is to investigate early detection of prostate cancer as part of the EU's new cancer strategy.

They talk about active surveillance for low-risk prostate cancer patients to avoid over-treatment, as well as the PSMA staging process for high-risk disease, and a caution on altering treatment without sufficient evidence. The importance of standardised MRI procedures and the need for quality control to avoid unnecessary biopsies is also discussed.

Prof. Dr. Nicolas Mottet (FR) is the chair of the EAU Guidelines prostate cancer panel. Prof. Phil Cornford (GB) is vice-chair of the same panel.

In this podcast, the new EAU ASCO Guidelines on penile cancer is discussed. The new guidelines are a total revision of prior versions and emphasises the importance of patient representatives and early palliative care. The panel collaborated with ASCO and integrated expertise from around the world.

This expert panel talk about diagnosis and staging, with emphasis on HPV testing and minimally invasive approaches to lymph nodes. Also, treatment of the primary tumour, with recommendations for a balanced discussion with patients and acknowledgement of the risk of recurrence. Organ-sparing surgery was recommended in cases where it is safe, with consideration for the effects on quality of life (QoL).

The conversation was led by Oscar Brouwer (NL), co-chair of the EAU ASCO Guidelines on penile cancer. He spoke with Dr. Philippe Spiess (US), Dr. Maarten Albersen (BE) and Mr. Arie Parnham (GB), all members of the penile cancer panel.

In this episode: Evanguelos Xylinas, Professor of Urology at Bichat-Claude Bernard Hospital in France, Fellow of the European board of Urology. And Fredrik Liedberg, Urologist and Professor at the Department of Urology, at Skåne University Hospital Malmö in Sweden.
Prof. Liedberg and Prof. Xylinas will discuss management of difficult bladder cancer cases.

In this episode, Dr. Hanny Cobussen-Boekhorst, a nurse practitioner (NP) and a member of the EAU guidelines panel for Female Lower Urinary Tract Symptoms (LUTS), discusses her motivation and contribution to the guidelines panel.

Multidisciplinary collaboration is the future, and as a nurse, Dr. Cobussen-Boekhorst talks about the benefits of having a nurse-specialist involved in female LUTS management. Nurses have experience and expertise in providing a patient-centred approach, with a focus on quality of life and education. This is essential when investigating the best treatment options, teaching-guidance from start-to-end of treatment (such as intermittent catheterisation or stoma care), and follow-up.

Dr. Cobussen-Boekhorst shares her experience as part of a multidisciplinary consultation for patients referred for urostomy, where a team of urologists, nurse practitioners, and other healthcare professionals discuss the options and the patient's understanding of the procedure.

Lastly, the importance of the EAUN guidelines for urostomy patients are discussed. These guidelines offer the latest medical insights, e.g., Bricker urostomy vs continent urostomy, with or without a bladder augmentation, stoma material, catheters.

In this podcast, Prof. Bhaskar Somani (GB), an associate of the EULIS - Working Group on ureteroscopic management of stones, and Mr. Patrick Jones (NO), a member of the EAU Young Academic Urology urolithiasis group, discuss the challenges of urolithiasis in pregnancy.

The management of kidney stones during pregnancy can be challenging for most urologists in terms of using the right diagnostics and treatment, to ensure the best outcomes for the patient and the foetus. A multidisciplinary approach to diagnosis and treatment is required (including the midwife).

Prof. Bhaskar and Mr. Jones share details on what type of imaging to use and what not to use, as well as treatment considerations.

Dr. Felix Campos-Juanatey (ES), a member of the EAU Guidelines Panel for Urethral Strictures, answers questions on the diagnosis of urethral strictures and follow-up after urethral surgery.

This podcast begins with details on what patient information is necessary to collect during an in-depth clinical interview and examination to make an accurate diagnosis.

Dr. Campos-Juanatey shares the latest guidelines on when and how to conduct regular follow-up with patients after urethral strictures, in order to detect any complications or recurrences. This includes a useful timeline from 3-months up to 5-years (or longer) depending on low risk- and high-risk patients, and the use of flow rate analysis, questionnaires and anatomical assessment.

Lastly, some information is included on how to evaluate if a urethral intervention has been successful or not, taking into account the practical and functional satisfaction of a patient.

In this edition, Dr. Margarida Manso (PT), associate member of the EAU Section of Female and Functional Urology (ESFFU), discusses female stress urinary incontinence (SUI).

Dr. Manso details the physiological elements of SUI in regards to the bladder neck and urethra, as well as the urinary sphincter.

The multiple causes behind SUI are outlined, including: ageing, radiotherapy trauma and neurological disease.

Dr. Manso shares information on the different treatment options starting with conservative management (lifestyle interventions and PFMT), followed by vaginal devices and surgical interventions.

Surgical interventions discussed include bulking agents, synthetic MUS, autologous fascial slings, colposuspension and external compression devices (such as ACT and AUS).

Dr. Manso concludes with an update on vaginal lasers for SUI, which are currently not recommended as a treatment option.

In this edition, Dr. Lazaros Tzelves (GR), a member of the EAU Guidelines Panel for non-neurogenic female LUTS, discusses underactive bladder (UAB) in women.

Dr. Tzelves clinically defines what an underactive bladder is, followed by sharing information on its prevalence and aetiology. UAB is difficult to diagnose and difficult to manage. Dr Tzelves discusses how urologists can diagnostically approach patients with suspected underactive bladder and what the options are for managing this condition conservatively.

Lastly, Dr. Tzelves talks about when surgical treatment is useful, and what options exist.

In this podcast, EAU Prostate Cancer Guidelines Panel members Prof. Nicolas Mottet (FR) and Prof. Philip Cornford (GB), have an in-depth discussion on active surveillance in prostate cancer.

The two experts elaborate in detail on what active surveillance is, including the difference between active surveillance and watchful waiting, which can often be mis-understood. Prof. Mottet and Prof. Cornford delve into the importance of maintaining quality of life and the fact that active surveillance does not mean no treatment but is considered if the patient will benefit from it.

More information is shared on the guidelines for active surveillance in prostate cancer and how often to repeat biopsies, MRI and PSA testing. Also, vital information about who the good candidates for active surveillance are, such as Gleason 3+3, as well as candidates that it is not suitable for, and the exclusion criteria.

Lastly, Prof. Mottet and Prof. Cornford discuss the problem of compliance and look at what data is currently available.

In this edition, we have Dr. Carme Mir (ES), chief editor of the UROONCO RCC editorial board, together with Prof. Alessandro Antonelli (IT) from the University of Verona and director of the Department of Urology at Borgo Trento Hospital, talking about the retroperitoneal approach to robotic partial nephrectomy (RPN).

Prof. Antonelli begins this interview with a review on transrectal and transperineal for retroperitoneal partial nephrectomy. He shares his experience and expert-knowledge on the likelihood of conversion of surgical strategy.

Dr. Mir and Prof. Antonelli conclude with a discussion on the X series systems from Intuitive and if they are mandatory for retro or not.

This expert interview took place during ERUS22, in Barcelona.

In this edition, we have Dr. Riccardo Bertolo (IT), the associate editor of UROONCO RCC editorial board, together with Dr. Alberto Breda (ES), Head of the Oncology Urology Unit and Kidney Transplant Surgical Team Urology Department, Fundació Puigvert, Barcelona, and Chairman of ERUS and president of the ERUS22 congress, talking about the novel alternative robotic platform that was recently launched in Europe.

Dr. Riccardo Bertolo and Dr. Alberto Breda share highlights on their first experiences with the Hugo robot in performing partial nephrectomy. They discuss the docking/port placement and give details about the Da Vinci experience (S/Si) in regard to facilitating the landing with this new technology.

They share views on the idea of whether or not the multi-carts Hugo robot will prevent the widespread diffusion of the retroperitoneal robotic approach to partial nephrectomy.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our EAU podcast channel for regular updates.

In this edition, Dr. Constance Thibault (FR), associate editor of the UROONCO PCa educational platform, discusses triplet therapy for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC).

In the last decade, the outcome of metastatic prostate cancer has been improved by intensifying the systemic therapy with the addition of docetaxel and/or new hormonal therapies. Clinicians now have several treatment options to offer their patients with mHSPC. This raises the issue of the optimal choice?

Dr. Thibault answers questions about why triplet therapy (ADT + DOCETAXEL + NHT) is recommended to mHSPC patients, and do all patients benefit from a triplet therapy or only specific subgroups?

Lastly, Dr. Thibault talks about which triplet therapy is recommended to use in clinical practice assuming that abiraterone and darolutamide are both approved in combination with ADT + DOCETAXEL for mHSPC patients.

During this episode, Dr. Thomas Seisen (FR), an associate member on the EAU Guidelines Panel for Non-Muscle Invasive Bladder Cancer, answers questions about metastatic upper urothelial cancer (UTUC) treatment options in the 2022 guidelines:

What are the systemic treatment options for metastatic UTUC in the first-line setting?
Can a maintenance systemic treatment be proposed to metastatic UTUC patients responding to first-line platinum-based chemotherapy?
What are the systemic treatment options for metastatic UTUC in the second-line setting?
What are the systemic treatment options for metastatic UTUC in the third-line setting?
Is there a role for surgery in the management of metastatic UTUC?

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates.

In this edition, we have Dr. Teele Kuusk (UK), the associate editor of the UROONCO RCC educational platform discussing kidney cancer highlights at the recent ESMO2022.

Dr. Kuusk begins with the reporting of several new trials and the accompanying results, which include: Phase 3 CheckMate-914, Phase 3 COSMIC-313, Phase 2 Keynote-B61, and Cohort 1 of LITESPARK-003 study.

After delivering the trial results, Dr. Kuusk shares the possible reasons why the adjuvant trials failed.

For more details on the results of the LITESPARK-003 study, you can watch this video featuring Assoc. Prof. Jaime Merchan (US), who presented at ESMO2022. https://kidney.uroonco.uroweb.org/video/cohort-1-of-litespark-003/

In this podcast, members of the EAU Guidelines Panel for RCC Prof. Axel Bex (DE) and Prof. Jens Bedke (DE), discuss renal cell carcinoma (RCC), with updates on treatments and current trials.

Prof. Bex and Prof. Bedke talk about what's new in adjuvant treatment for patients with high-risk RCC after radical nephrectomy. This follows with discussions on the combination and triplet trials, as well as the recent developments in the systemic treatment of advanced RCC.

Other topics include cytoreductive surgery, metastasectomy, systemic therapy and observation. Lastly, Prof. Axel and Prof. Bedke analyse what the role of Stereotactic Body Radiotherapy (SBRT) in advanced RCC might be.

In this edition we have Dr. Benoît Peyronnet (FR), a Panel Member, and Dr. Néha Sihra (UK), an associate member of the EAU Guidelines Panel for female lower urinary tract symptoms, discussing overactive bladder syndrome (OAB) in women.

Ms. Sihra answers questions about what to do when evaluating an overactive bladder patient. She covers the importance of clinical history, and which type of examinations to do, as well as giving details on bladder diaries and symptom scores.

More details are given about specific dietary measures and conservative treatments for overactive bladder patients including fluid intake, weight and specific exercises.

Ms. Sihra also talks about when to use, and more importantly, when not to use, various medications. And lastly, she looks at what the alternatives are for patients who fail first time treatments.

In this podcast, EAU Guidelines office member, Prof. Philip Cornford (GB), and Prostate Cancer Panel patient representative, Dr. Erik Briers (BE), share their views on the importance of patient input in authoring the EAU Guidelines.

Our discussants review the relationship between specialists and their patients, and how they can create better advocacy, as well as, increased involvement going forward in writing the guidelines.

In this edition, Prof. Christian Radmayr talks about the importance of the dissemination of the EAU Guidelines.

Prof. Christian Radmayr is a member of the Paediatric Urology Guidelines Panel and chair of this panel since 2018. In this episode he touches on the various platforms through which the EAU Guidelines are disseminated, which initatives have the most impact and how clear communication of medical guidelines is vital in the current digital climate.

In this podcast, Prof. Peter Gilling (NZ), Professor of Surgery at the University of Auckland, shares details with us on the main findings of the WATER study.

Prof. Gilling gives us some insights into the five-year results of the WATER study, a pivotal trial that compares Aquablation versus transurethral resection of the prostate (TURP). The results were presented at the 2022 EAU Annual Congress.

He also identifies the ideal patients for Aquablation, what steps of the procedure could be improved with this technique and looks at the future of the Aquablation technique.

In this edition, we have Prof. Tamsin Greenwell (GB), a panel member on the EAU Guidelines Panel for Urethral Strictures, discussing the management of female urethral stricture disease.

Prof. Greenwell begins with an overview on the causes of female urethral strictures and how a diagnosis should be made. Following this she answers questions on treatment options, including what type of urethroplasty to use (dorsal and ventral), and which tissue is best for substitution.

She reports on the outcomes of female urethroplasty, and concludes with a discussion on adverse effects from tissue harvest for use in substitution urethroplasty.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates.

In this podcast, Dr. Vasileios Sakalis (GR), a member of the EAU Guidelines Panel for Male Lower Urinary Tract Symptoms, reports on the new section in the guidelines relating to Male Urinary Incontinence.

Dr Vasileios Sakalis begins with information on an important addendum to the 2022 Male LUTS Guidelines with regard to the new incontinence section, and the reasons why this new section has been included in Male LUTS.

He talks about an important study that has been included in this section, as well as updates in the pharmacological management of Male LUTS.

Lastly, Dr Sakalis shares his knowledge on novelties in the diagnostic evaluation of male patients with Lower Urinary Tract Symptoms.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates.

In this commentary, Assoc. Prof. Fardod O'Kelly (IE), member of the EAU Guidelines Panel for paediatric urology, shares his expert knowledge on nocturnal enuresis, also known as bedwetting.

Assoc. Prof. O'Kelly begins by answering questions on the prevalence of bedwetting among children, teenagers and into adulthood. More details are given to define this heritable condition, as well as covering the non-genetic risk factors.

Making a correct diagnosis can be challenging, and the condition is often mis-diagnosed, but Assoc. Prof. O'Kelly discusses how to make a good diagnosis.

Lastly, the different management strategies are reviewed.

For more EAU podcasts, please go to your favourite podcast app and subscribe to our podcast channel for regular updates.

Professors Giulio Del Popolo and Gilles Karsenty (panel members), are joined by Dr. Stefania Musco (associate member) of the EAU Guidelines Panel for Neuro-urology, to talk about N-SUI.

In this commentary three experts share their knowledge of neurogenic stress urinary incontinence (N-SUI); from surgical management, urodynamic evaluation, bulking agents, and other treatments, including artificial sphincter.

Prof. Giu lio Del Popolo (IT) begins with an explanation to the surgical management of N-SUI and assesses why it is considered such a challenge.

Following this, Dr. Stefania Musco (IT) reviews the importance of urodynamic in neurogenic stress urinary incontinence. Is there a place for bulking agents? And if so, in which patients?

Prof. Giulio Del Popolo analyses the use of autologous sling or synthetic mid-urethral tape for treating female neurogenic stress urinary incontinence?

Lastly, Prof. Gilles Karsenty (FR) gives his assessment on who the best candidates for artificial sphincter are.

Dr. Sajjad Rahnama'i (NL), a member of the EAU Section of Female & Functional Urology, will discuss neurogenic detrusor overactivity, including its diagnosis and treatment.

Several questions will be answered. What is neurogenic detrusor overactivity, and can it be a serious condition? What is the standard diagnostic workup of a patient in whom we suspect neurogenic detrusor overactivity? What is the first line treatment of neurogenic detrusor overactivity? What are the second- and third-line treatments? And lastly, how should patients with neurogenic detrusor overactivity be followed up, and by whom? This podcast is supported by an unrestricted education grant from Medtronic.

For more EAU podcasts, please subscribe to our podcast channel for regular updates.

Dr. Richard Cathomas, medical oncologist from Zurich in Switzerland discusses Immunotherapy in muscle-invasive bladder cancer.

He goes into the mechanism of action of immunotherapy and why could it work well in bladder cancer.
Where do we currently stand with the use of immunotherapy in the NEOADJUVANT setting of muscle invasive bladder cancer? And what is currently the best place to integrate immunotherapy for METASTATIC bladder cancer?

Prof. Dr. Cathomas closes with the answer to the question of why some patients benefit much more than others from immunotherapy.

Prof. Dr. Richard Cathomas is oncologist panel member on the EAU Guidelines for muscle-invasive bladder cancer.

In this second edition of two updates, Professor Nicolas Mottet, the chair of the EAU Guidelines panel for prostate cancer, discusses which are the most important changes and new recommendations in the new EAU Guidelines for prostate cancer for 2022 relating to treatment approaches.

In this first edition of two updates, Professor Nicolas Mottet, the chair of the EAU Guidelines panel for prostate cancer, highlights the work of the panel.
His talk includes new systematic reviews, and outlines which are the most important changes in the new EAU Guidelines for prostate cancer for 2022 relating to the definition of clinically localized and clinically significant prostate cancer, diagnostic evaluation, particularly transperineal biopsy. Professor Nicolas Mottet also discusses key points relating to staging and imaging.

What exactly is pain? What do I have to know about pain if I am treating patients with chronic pelvic pain? What is necessary to diagnose a chronic pelvic pain syndrome? What factors are key to successfully treat patients with a chronic pelvic pain syndrome? And what are the psychological aspects of chronic pain? Prof Daniel Engeler answers these questions.

Prof Engeler is chairman of the EAU Guidelines panel on Chronic Pelvic Pain.

Dr Bela Köves answers questions about the changes in the guidelines chapter of recurrent urinary tract infections. And in particular, he elaborates on the question, what the most important updates are for the specific preventive approaches. Are there any changes regarding lifestyle advices or behavioral modifications?

The second part of the podcast covers the updates about the use of topical oestrogen, immunoactive prophylaxis, the changes about prophylaxis with probiotics and cranberries.

Dr Bela Köves is a member of the EAU Guidelines panel on urological infections.

In this edition, we have Professor Berk Burgu, a member of the EAU Guidelines panel for Paediatric Urology, discussing vesico-ureteral reflux in children, including its diagnosis and treatment.

We get answers to the question what is vesico-ureteral reflux is and Prof. Burgu explains the importance. Should we treat vesico-ureteral reflux immediately after being diagnosed? Is there a structured diagnostic work-up for vesico-ureteral reflux?

In the last part of the podcast, Prof. Burgu discusses the options for the surgical treatment of reflux.

In this edition, we have Dr. Toine van der Heijden discussing the three different diversions mentioned in the guideline after cystectomy - uretero cutaneostomy, ileal conduit and an orthotopic neobladder – along with the reasons for choosing a certain diversion and helping the patient to decide.

Dr. Toine van der Heijden is a member of the EAU Guidelines panel for Muscle Invasive Bladder Cancer.

The new guidelines on Non-neurogenic Female LUTS have replaced the old Urinary Incontinence Guideline. Dr. Arjun Nambiar discusses the thought process behind this and tells what's new. He also goes deeper into the process that guidelines users or readers may not be aware of.

Dr. Arjun Nambiar is member of the EAU Guidelines panel for non-neurogenic Female LUTS.

Dr. Sachin Malde catches up with us about the current status and future challenges in minimally invasive treatments for BPO. He elaborates on the surgical options and the EAU guidelines recommendations about the newer surgical treatments for BPO.

We also gain insight into the criteria the guidelines panel use to make a recommendation about a particular treatment. And finally, Dr. Malde discuss the future developments that he think will help to strengthen the recommendations made by the EAU guidelines in this area.

Dr. Sachin Malde is an associate member of the EAU Guidelines panel on Management of Non-neurogenic Male LUTS.

How can we improve the organ pool for kidney transplantation and how do we implement all alternatives in the current transplant teams?

Dr. Oscar Rodriguez Faba is an associate member of the EAU Guidelines panel for kidney transplantation and talks about these questions in this podcast.

Oscar Rodriguez Faba closes with the answer to the question if the results are comparable to cadaveric donors and conventional living donors.

Why bring Psychology to the management of male sexual dysfunction, which specific problems are generally approached in the psychological clinical setting and what are there emerging topics on the intersection of psychology and male sexual health are the questions that Prof. Joana Carvalho answers.

Prof. Joana Carvalho is a member of the EAU Working Group on Sexual and Reproductive Health.

Prof. Carvalho closes this podcast talking about the role of scientific and professional societies in the promotion of a biopsychosocial approach to male sexual problems.

Dr. Josine Quaedackers is a member of the EAU Guidelines panel on Paediatric Urology.

In this podcast, she explains what microlithiasis is. In adults testicular microlithiasis has been associated with an increased risk of testicular malignancy. Dr. Josine Quaedackersanswered the question of whether this is the same in children.

She examines the question of what happens to the risk when the child with testicular microlithiasis becomes an adult. And finally, she gave the advice in case of an incidental finding of testicular microlithiasis in an adolescent boy.

Dr. Alexandra Masson-Lecomte is a member of the EAU Guidelines panel on Upper Urinary Tract Urothelial Cell Carcinoma (UTUC).

In this podcast, she speaks about the challenges and evidence regarding the administration of perioperative chemotherapy in high-risk UTUC.

She also discusses post-operative chemotherapy and alternatives to cisplatin based chemo.

Dr Kay Thomas is a member of the EAU Guidelines urolithiasis panel. In this podcast, she talks about the basic evaluation that should be done for all stone formers. She also elaborates on the question of who needs more specific evaluation and what investigations would you recommend. Finally, she gives her recommendations for a patient with low risk and high risks of recurrence.

Prof. Alberto Breda, the Chair of the EAU Guidelines panel for Kidney transplantation, discussing the latest advances in surgical techniques for organ retrieval and kidney transplantation surgery.

With over 400 peer-reviewed papers published, Prof. Bhaskar Somani is an editorial board member of 4 journals and a reviewer for 15 journals. In this episode, he shares his experience in publishing scientific papers. The scope of his podcast includes:

Tips and tricks for a successful outcome
How to select a topic or a journal
Core skills needed in publishing a scientific paper
How to deal with rejection
Secrets of successful teams who publish numerous articles

Guest: Prof. Bhaskar Somani, Consultant Urological Surgeon within Medicine at the University of Southampton

In this episode, Prof. Christian Radmayr shares his expert insights in treating undescended testes covering topics such as:

Frequency of undescended testes among boys
Reasons for its occurrence
How to classify undescended testes
When to start treatment
Options for surgical therapy, and more

Guest: Prof. Christian Radmayr, the Chair of the EAU Guidelines panel for Paediatric Urology

What are the recommendations for the management of stage I seminoma and stage I non-seminoma after orchiectomy? Tune in as Dr. Stefanie Fischer provides vital information on this, as well as, the risks of relapse after orchiectomy, and the pros and cons of various strategies.

Guest: Dr Stefanie Fischer, oncologist member of the EAU Guidelines panel for Testicular Cancer

In part 2 Prof. Nicolas Mottet discusses which are the most important changes in the new EAU Guidelines for Prostate Cancer treatment related to genetic testing, M1 disease and Castration-resistant prostate cancer (CRPC).

Listen also to part 1 about perineal biopsy, staging PSMA, adjuvant Radio Therapy.

In this first part, Prof. Nicolas Mottet talks about the most important changes in the new EAU Guidelines for Prostate Cancer treatment and discusses in more detail perineal biopsy, staging PSMA, adjuvant Radio Therapy.

prostatecancer

Data has shown the prevalence of infertility has increased over the last decades. In this episode, Dr. Paolo Capogrosso explores if this is also the case in males. Dr. Capogrosso discusses:

Any novel tests to better investigate male fertility
What treatment to suggest if the patient has evidence of increased DNA fragmentation and normal semen parameter
Updates on varicocele treatment, and more

Guest: Dr Paolo Capogrosso, an associate of the EAU Guidelines panel for Sexual and Reproductive Health

Generally speaking, while NMIBCs have a more favourable prognosis compared to their MI counterpart, they are not the same and seem to behave differently (i.e. some are relatively indolent, others have aggressive features). In this episode, Prof. Paolo Gontero explains why. He will also discuss the following:

What is the current, best-recommended way for risk stratification of NMIBCs
If there is a way to predict the risk of recurrence of a NMIBC
How to tailor treatment recommendations

Guest: Prof. Paolo Gontero, member of the EAU Guidelines panel for Non-Muscle Invasive Bladder Cancer

Welcome to the EAU Podcast. In this episode, we have compiled some useful background information on why the EAU is branching out into podcasting, how it will engage listeners, and reach new audiences.

In this episode, we compiled tips and tricks in how to record a podcast. These will include useful information on:

How to prepare for a recording (e.g. practicing your speech and using your mobile as a recording device)
What to take into account during the recording process
What to do next after recording

We also discussed why the EAU is branching out to podcasting, how it will engage listeners, and reach new audiences.