Cleveland Clinic Cancer Advances: Recent Episodes
Cleveland Clinic Taussig Cancer Institute
A Cleveland Clinic podcast for medical professionals exploring the latest innovative research and clinical advances in the field of oncology.
As new therapies move through clinical trials, the management of uveal melanoma is entering a period of significant change. In this episode of Cancer Advances, Arun Singh, MD, discusses emerging strategies to avoid radiation, prevent radiation-related vision loss and shrink tumors before definitive treatment. Learn how these innovations address longstanding unmet needs and reshape care for patients with this rare ocular malignancy.
How can oncologists initiate meaningful goals-of-care discussions earlier in the disease course? In this episode, Dr. Natalie Jacobowski outlines practical communication strategies, including language, timing and approaches to reduce stigma and align care with patient values. She emphasizes how early, transparent dialogue, and framing concerns as shared worries, can enhance decision-making across the cancer continuum, including for younger patients.
How can better data improve decision-making in a curable but nuanced disease like testicular cancer? This episode explores how large language models can turn unstructured clinical notes into actionable insights, helping clinicians refine treatment selection, understand practice variation and balance cure with long-term toxicity management.
Is there a role for earlier integration of lutetium PSMA therapy in mCRPC management? Emerging evidence supports its use in the pre-taxane setting, prompting a shift in sequencing decisions. This episode outlines patient selection, PSMA imaging requirements and how to balance disease aggressiveness, tolerability and real-world considerations when choosing between lutetium and chemotherapy.
As cancer care becomes increasingly personalized, treatment deescalation is emerging as a key strategy to balance efficacy with quality of life. In this episode of Cancer Advances, Jame Abraham, MD, Enterprise Chair of Hematology and Medical Oncology at Cleveland Clinic, discusses how clinicians are rethinking dose intensity, duration and therapeutic selection across disease settings. Learn how evolving evidence, patient preferences and emerging technologies like AI are shaping treatment decisions and redefining standards of care.
How can we better predict progression and outcomes in a disease where treatment decisions must be made in days, sometimes hours? In this episode of Cancer Advances, Moaath Mustafa Ali, MD, MPH, discusses emerging longitudinal and evolutionary modeling approaches that integrate clinical, genomic and treatment data over time to improve risk stratification in acute myeloid leukemia. Learn how these models may support earlier, more informed decisions around therapy selection, relapse risk and long-term management.
Young patients requiring pelvic radiation face limited fertility preservation options. In this episode of Cancer Advances, Robert DeBernardo, MD, and Johanna Kelley, MD, both gynecologic oncologists at Cleveland Clinic, discuss uterine transposition—a novel surgical approach that protects both ovarian function and the uterus—using a real world rectal cancer case. Learn which patients may benefit, how the multidisciplinary model works and what this technique could mean for counseling, referrals and long term reproductive outcomes.
Shilpa Gupta, MD, Genitourinary Medical Oncologist, joins the Cancer Advances podcast to explore how perioperative immunotherapy and ctDNA are redefining management of muscle-invasive bladder cancer. She reviews emerging phase III data and explains how it can inform treatment selection, referral timing and adjuvant decision making in clinical practice.
Lilyana Angelov, MD, Neurosurgeon and Director of the Cleveland Clinic Gamma Knife Center, Samuel Chao, MD, Radiation Oncologist and Associate Director of the Gamma Knife Center; and Ajit Krishnaney, MD, Neurosurgeon in the Center for Spine Health, join the Cancer Advances podcast to share insights from 20 years of a multidisciplinary spine tumor board. Learn how multidisciplinary strategies and newer technologies are improving decision-making, local control and patient outcomes.
Amy Smith, MD, Pediatric Neuro-Oncologist, joins the Cancer Advances podcast to discuss recent progress in pediatric neuro-oncology. Listen as Dr. Smith explains the advances in tumor biology that are shaping treatment decisions and shares how recent FDA approvals for pediatric low-grade gliomas and diffuse midline gliomas are improving disease control and patient outcomes.
Brian Barnett, MD, Director of the Cleveland Clinic Psychiatric Treatment Resistance Program, joins the Cancer Advances podcast to discuss adjustment disorder in patients with cancer. Dr. Barnett shares how oncologists can better recognize this condition and provides insights on screening and treatment strategies. He also highlights emerging research on psychedelic-assisted therapy that may expand care options for these patients.
Thuy Nguyen, DAOM, LAc, Section Head of Acupuncture for the Wellness ad Preventive Medicine Department at Cleveland Clinic, joins the Cancer Advances podcast discuss how acupuncture is being integrated into cancer care. Listen as she explains the evidence behind using acupuncture for managing treatment-related symptoms, how acupuncture works biologically, key safety considerations and when oncologists should consider referral as part of an integrative oncology approach.
Director of the Inpatient Leukemia Unit, Anjali Advani, MD joins the Cancer Advances podcast to break down the latest acute myeloid leukemia clinical trials. From venetoclax-based regimens to emerging menin inhibitors and mutation-driven strategies, listen as Dr. Advani explains how rapid genomics, novel combinations and evolving transplant decisions are reshaping AML care and what still lies ahead for high-risk disease.
Could removing heat improve safety in endoscopic mucosal resection? Florida Division Chair of the Department of Gastroenterology, Hepatology and Nutrition, and the Florida Region Director for Endoscopy, Tolga Erim, DO, joins the Cancer Advances podcast to break down cold EMR how it compares to traditional EMR, including key differences in bleeding risk, recurrence rates, and clinical trade-offs.
Mina Lobbous, MD, MSPH, Neuro-Oncologist and Medical Director of the Adult Neurofibromatosis and Schwannomatosis Clinic at Cleveland Clinic, joins the Cancer Advances podcast to talk about the landscape of neurofibromatosis and schwannomatosis care. Listen as Dr. Lobbous emphasizes the importance of coordinated pediatric‑to‑adult care, highlighting the emergence of MEK inhibitors and transformational advances in imaging and genomics.
The Cancer Advances Podcast welcomes back Nathan Mesko, MD, Vice Chair of Global Clinical Operations for the Department of Orthopaedic Surgery and Center Director for Musculoskeletal Oncology at Cleveland Clinic to talk about chemotherapy, limb salvage surgery and how 3D printed custom implants are reshaping outcomes in osteosarcoma. Dr. Mesko also shares a remarkable pediatric case whose complex reconstruction highlights the power of multidisciplinary care, surgical innovation and long term functional recovery.
Bethany Samuelson Bannow, MD, Director of Classical Hematology at Cleveland Clinic, joins the Cancer Advances podcast to discuss the evolving field of classical hematology and what it means for managing complex non-malignant blood diseases. Listen as she covers emerging gene therapies, bispecific antibodies, cancer-associated thrombosis, and practical referral guidance for conditions like ITP, TTP, and sickle cell disease.
Julie Lang, MD, Breast Surgical Oncologist, joins the Cancer Advances podcast to discuss advancing care for patients with inflammatory breast cancer. Listen as Dr. Lang outlines key clinical features that distinguish IBC from infection, evidence-based sequencing of neoadjuvant therapy, surgery and radiation, and highlights emerging tools and translational research efforts aimed at improving outcomes in this aggressive subtype.
Associate Staff and Physician Scientist at Cleveland Clinic Children’s, Richa Sharma, MD, joins the Cancer Advances podcast to discuss the launch of a National DNA Repair and Telomere Biology Disorder Tumor Board. Listen as Dr. Sharma explains the cancer predisposition associated with these rare inherited disorders, the challenges of treating malignancy in patients with impaired DNA repair, and how a multidisciplinary, national tumor board can help clinicians navigate complex treatment decisions and toxicity risks.
Radiation Oncologist and Physician Scientist Jacob Scott, MD, DPhil, joins the Cancer Advances podcast to discuss how chemograms may change the way oncologists select chemotherapy using transcriptomic data and predictive modeling. Listen as Dr. Scott shares how this approach applies the logic of an antibiogram to cancer care, ranks cytotoxic therapies based on tumor sensitivity, and supports more personalized treatment decisions for patients.
Medical Director of the Women's Comprehensive Health and Research Center and Professor of OB/GYN and Reproductive Biology, Pelin Batur, MD, joins the Cancer Advances podcast to discuss updated guidance on contraceptive care during and after cancer. Listen as Dr. Batur breaks down the latest multidisciplinary recommendations, reviews cancer-specific risks and misconceptions around hormonal contraception, and explains how shared decision-making can help prevent unintended pregnancy, reduce harm, and improve long-term survivorship care.
Mohammad Dwidar, PhD, Assistant Staff in the Lerner Research Institute and Assistant Professor of Molecular Medicine at Cleveland Clinic Lerner College of Medicine, joins the Cancer Advances podcast to discuss the emerging role of engineered bacteria in cancer treatment. Listen as Dr. Dwidar explores the history of bacteria-based immunotherapy, strategies to enhance tumor specificity and safety, and how targeting tumor metabolites like kynurenine could open new therapeutic avenues across solid tumors.
Jaroslaw P. Maciejewski, MD, PhD, Chair of the Translational Hematology and Oncology Research Department at Cleveland Clinic, joins the Cancer Advances podcast to take a deeper look at inborn errors of immunity and their role in clonal T-cell expansion and large granular lymphocyte (LGL) leukemia. Listen as Dr. Maciejewski explains how subtle immune deficiencies may drive disease, what this means for diagnosis and treatment, and how these insights could reshape how clinicians think about immune-mediated bone marrow failure.
Paula Escobar, MD, a Breast Surgical Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to provide an inside look into endoscopic nipple-sparing mastectomy. Listen as Dr. Escobar breaks down how the procedure works, who is an ideal candidate and what this approach could mean for cosmetic outcomes, recovery, and the future standard of care.
Radiation Oncologist and Co-Director of the Genitourinary Program, Shalini Moningi, MD, joins the Cancer Advances podcast to discuss the latest advances in radiation therapy for prostate cancer. Listen as Dr. Moningi talks about SBRT, adaptive radiation, emerging biomarker data, and how these innovations are reshaping treatment selection, toxicity profiles, and patient's quality of life.
Breast density affects 50% of women and can significantly impact both cancer risk and early detection. Breast Radiologist, Paulette Turk, MD, and Medical Breast Program Director, Lakshmi Khatri, MD, join the Cancer Advances Podcast to discuss breast density, its risk implications and the role of supplemental screening. Listen as they explain how Cleveland Clinic is defining practical screening pathways in an area where national guidelines continue to evolve.
Shahzad Raza, MD, Hematologist at Cleveland Clinic, joins the Cancer Advances podcast to share insights from the RedirecTT-1 study. This study, presented at the 2025 American Society of Hematology (ASH) Annual Meeting, explores combining two bispecific antibodies, talquetamab and teclistamab, for patients with relapsed/refractory multiple myeloma with extramedullary disease. Listen as Dr. Raza discusses disease biology, outcomes, safety considerations and why this approach could be a major step forward for high-risk myeloma care.
Certified Oncology Social Worker Jane Dabney, MSW, LISW-S, OSW-C, joins the Cancer Advances Podcast to talk about the vital role social workers play in blood cancer care. Listen as she explains how social work helps identify barriers to transplant and cellular therapy, supports patient and caregiver preparedness, and strengthens continuity of care.
Urologic Oncologist at Cleveland Clinic Weston Hospital, Alberto Pieretti, MD, joins the Cancer Advances Podcast to talk about how innovations in imaging, biomarkers and multidisciplinary care are reshaping the diagnosis and management of prostate cancer. Hear how advances such as PSMA PET scans, biomarker-guided biopsies and precision therapies are improving outcomes and quality of life for patients.
Joseph Skitzki, MD, Director of Melanoma and Cutaneous Oncology Surgery at Cleveland Clinic, joins the Cancer Advances podcast to discuss how neoadjuvant immunotherapy is transforming melanoma treatment. Listen as Dr. Skitzki explains how this approach is improving survival and reducing the need for extensive surgery.
Allison Winter, MD, Hematology Oncologist and Medical Director for VeloSano, returns to the Cancer Advances podcast to discuss the latest advances in diagnosing and managing primary CNS lymphoma. Listen as Dr. Winter shares how evolving treatment strategies, including CAR T-cell therapy and novel clinical trials, are improving outcomes and helping preserve cognitive function.
Pregnancy-associated breast cancer is rare and complex, requiring careful coordination across specialties. Erin Roesch, MD, Breast Medical Oncologist, joins the Cancer Advances Podcast to discuss how a multidisciplinary team approach helps optimize treatment timing, ensures maternal and fetal safety, and supports patients through diagnosis, therapy, and recovery.
Radiation oncologist in the Burkhardt Brain Tumor and Neuro-Oncology Center and Associate Director of the Gamma Knife Center, Samuel Chao, MD, joins the Cancer Advances podcast to talk about how advances in Gamma Knife radiosurgery are transforming treatment for patients with brain metastases. Hear how innovations in imaging, staging, and safety are allowing clinicians to treat more lesions while preserving brain function.
Lauren Kopicky, DO, Breast Surgical Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to discuss the evolving management of the axilla in breast cancer care. Listen as Dr. Kopicky reviews key clinical trials, ongoing research, and how de-escalation strategies are shaping patient care, outcomes, and quality of life.
Radiation Oncologist and Co-Director of the Sarcoma Program, Shauna Campbell, DO, returns to the Cancer Advances Podcast, this time diving into something a bit different - how low dose radiation therapy could help with osteoarthritis. Listen as Dr. Campbell explains how radiation works as an anti-inflammatory treatment, the types of patients who may benefit most, and how it compares with common options like joint injections or surgery.
Theranostics is changing the way we approach cancer care by combining advanced imaging with targeted therapy. Elcin Zan, MD, Chair of the Department of Nuclear Medicine at Cleveland Clinic joins the Cancer Advances Podcast to discuss how theranostics is being used in prostate cancer, for neuroendocrine tumors and its potential use for other cancers.
Samuel Trosman, MD, a Head and Neck Surgeon at Cleveland Clinic Weston Hospital, joins the Cancer Advances Podcast to discuss personalized approaches to thyroid cancer surgery. Listen as Dr. Trosman shares evolving surgical strategies, risk assessment and the role of molecular testing in guiding care.
Emotional distress is common during cancer treatment, but research shows it may also impact treatment outcomes. Psychosocial Oncologist Shiyao Wang, MD, joins the Cancer Advances Podcast to discuss the STRESS-LUNG-1 trial and how addressing emotional distress can potentially influence treatment response.
Jame Abraham, MD, Chair of the Department of Hematology & Medical Oncology at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to discuss how artificial intelligence (AI) is transforming oncology care. Listen has he shares insights from Cleveland Clinic’s recent AI in healthcare conference, real-world applications such as clinical documentation and trial matching, and how AI may reshape research, patient care, and the future of cancer treatment.
Orthopedic Oncologist at Cleveland Clinic in Florida, Jorge Manrique-Succar, MD, returns to the Cancer Advances Podcast to share the latest advances in treating metastatic bone disease. Listen as Dr. Manrique talks about early intervention, advanced surgical techniques, and multidisciplinary collaboration are improving outcomes for cancer patients with skeletal-related complications.
Wen Wee Ma, MBBS, Enterprise Vice Chair for Research and Director of the Novel Cancer Therapeutics Center, joins the Cancer Advances Podcast to discuss a phase 1 trial of KB707 presented at ASCO 2025. This innovative therapy delivers IL-2 and IL-12 directly to the lungs through inhalation, aiming to minimize side effects and improve outcomes for patients with lung tumors. Dr. Ma shares early trial results and what they could mean for the future of cancer treatment.
Kelley Kozma, DO, MS, Medical Director for Oncology at Cleveland Clinic Martin Health in Florida, to discuss how targeted therapies, next generation sequencing, and personalized medicine are transforming breast cancer care. Listen as Dr. Kozma shares how innovations like HER2-low targeting, liquid biopsy, and circulating tumor DNA are helping clinicians tailor treatments and improve outcomes.
Brian Burkey, MD, MEd, Interim Director of the Scully Walsh Cancer Center and Division Chair of Otolaryngology Head and Neck Surgery at Cleveland Clinic in Florida, joins the Cancer Advances Podcast to talk about management strategies for clinically node-negative salivary gland cancer. Listen as Dr. Burkey highlights findings from an outcomes study and share strategies to better identify high-risk patients who may benefit from more aggressive treatment.
George Stark, PhD, and Christine McDonald, PhD, from Cleveland Clinic’s Lerner Research Institute, join the Cancer Advances Podcast to discuss the development of PALA as a novel immunostimulatory agent in oncology. Listen as they highlight promising preclinical data across multiple tumor types, potential for combination therapies and plans for clinical translation, including topical use for skin cancer.
The Cancer Advances Podcast welcomes back Sudha Amarnath, MD, a Radiation Oncologist and Co-Director of the Gynecologic Cancer Program at Cleveland Clinic to discuss the potential of self-collected HPV tests to expand access to cervical cancer screening. Listen as Dr. Amarnath shares insights into how these tests work, their FDA approval, and their potential to reach underserved populations who face barriers to traditional screening methods.
Megan Kruse, MD, a Medical Oncologist and Director of the Clinical Breast Cancer Research Program at Cleveland Clinic joins the Cancer Advances Podcast to share breast cancer research highlights from the 2025 ASCO Conference. She discusses key findings from studies in metastatic hormone receptor-positive, triple-negative, and HER2-positive breast cancer, including potential practice-changing data on oral SERDs, antibody-drug conjugates, and ctDNA testing.
Rafael Arteta-Bulos, MD, a Genitourinary Medical Oncologist at Cleveland Clinic’s Maroone Cancer Center in Weston, Florida, joins the Cancer Advances Podcast to discuss the use of virtual reality in the care of patients with cancer. Dr. Arteta shares how this emerging technology is being studied as a supportive tool to reduce distress, anxiety, and improve overall well-being during chemotherapy.
Laura Bukavina, MD, MPH, a Urologic Oncologist and Translational Research Lead for genitourinary oncology at Cleveland Clinic joins the Cancer Advances Podcast to talk about strategies to improve the survivorship experience for women with bladder cancer, including treatment advances, quality-of-life considerations and encouraging open conversations to drive better survivorship programs.
Akriti Jain, MD, a Hematologist and Medical Oncologist specializing in leukemia and myeloid disorders at Cleveland Clinic, joins the Cancer Advances Podcast to discuss personalizing treatment approaches for myelofibrosis-associated anemia. Listen as Dr. Jain provides insights into the evolving therapeutic landscape, explaining how the field has expanded beyond single-agent therapy.
The Cancer Advances Podcast welcomes back Emre Gorgun, MD, Vice Chair of the Department of Colorectal Surgery and Co-Director of the Endoluminal Surgery Center at Cleveland Clinic, for his fifth appearance to discuss endoscopic submucosal dissection (ESD) in managing early-stage colorectal cancer. Listen as Dr. Gorgun outlines the technique, compares it to traditional surgical approaches, and shares insights from recent research demonstrating its safety, oncologic efficacy, and impact on quality of life.
Christopher Weight, MD, Director of Urologic Oncology at Cleveland Clinic joins the Cancer Advances podcast to discuss using artificial intelligence to predict prostate cancer outcomes after radical prostatectomy. Listen as Dr. Weight explains how the algorithms can analyze standard prostate pathology slides to better predict which patients will likely experience cancer recurrence after surgery, potentially revolutionizing post-operative management strategies.
Hematologist and medical oncologist, Moaath Mustafa Ali, MD, MPH joins the Cancer Advances Podcast to talk about the impact of p53 mutations in patients with acute lymphoblastic leukemia (ALL). Listen as Dr. Mustafa Ali explains findings from a large real-world dataset, challenges in data collection, and how these insights may guide future treatment strategies.
Jamie Ku, MD, Director of the Head and Neck Robotic Surgery Program at Cleveland Clinic joins the Cancer Advances Podcast to discuss the newly released ASCO clinical practice guidelines for transoral robotic surgery (TORS) in patients with HPV-positive oropharyngeal cancer. Listen as Dr. Ku, who co-chaired the ASCO expert panel, provides insight into the multidisciplinary process behind the guidelines, outlines key recommendations for patient selection and explains the role of TORS as a minimally invasive surgical approach.
Matteo Trucco, MD, Director of the Children’s Cancer Innovative Therapy Program, joins the Cancer Advances Podcast to discuss the Cleveland Clinic Children's recent recognition as the first center in the nation to receive pediatric cancer subcommittee accreditation from the Commission on Cancer. Learn how this milestone is not only advancing pediatric cancer care at Cleveland Clinic but also shaping national benchmarks for multidisciplinary pediatric oncology programs.
Chair of the Department of Gastroenterology, Hepatology and Nutrition, Michelle Kang Kim, MD, PhD, joins the Cancer Advances podcast to discuss her team’s innovative work using electronic health records (EHR) to develop a predictive model for noncardiac gastric cancer. Listen as Dr. Kim explains how the model uses common clinical variables to flag high-risk patients who may benefit from endoscopic screening.
Brian T. Hill, MD, PhD, Director of the Lymphoid Malignancies Program at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the latest updates in first-line therapy for chronic lymphocytic leukemia (CLL). During this episode, Dr. Hill explains the shift from traditional chemoimmunotherapy to more precise, targeted treatments, and how customized therapy is transforming patient outcomes.
The Cancer Advances Podcast welcomes back Abhay Singh, MD, MPH, Director of the CHIP Clinic at Cleveland Clinic, to explore the evolving landscape of survivorship care. Listen as Dr. Singh provides insights on how personalized, patient-centered approaches are being integrated with shared care models to address late effects, psychological challenges, and the needs of a growing population of cancer survivors.
Abhay Singh, MD, MPH, Director of the CHIP Clinic at Cleveland Clinic, joins the Cancer Advances Podcast to discuss a major new study exploring the link between GLP-1 receptor agonists and the risk of hematologic malignancies in patients with diabetes. Tune in to hear how GLP-1s, best known for managing diabetes and obesity, may hold promise for cancer prevention and what this could mean for future cardio-oncology care.
The Cancer Advances Podcast is joined by the Chair of the Division of Pediatric Hematology Oncology and Director of the Bone Marrow Transplant Program, Rabi Hanna, MD, along with Ilia Butoriarov, MD, a physician at the Division of Pediatric Hematology Oncology leading the Leukemia Lymphoma Program to discuss evolving approaches to treating pediatric Hodgkin lymphoma. Listen as they talk about how novel therapies, including checkpoint inhibitors and PET-guided treatment strategies, are reshaping patient care and help avoid the need for bone marrow transplant.
Alok Khorana, MD, Director of the Gastrointestinal Malignancies Program at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to break down the latest research on early-onset biliary tract cancer, diving into the genetic and molecular differences that set it apart. Listen as Dr. Khorana addresses the challenges in diagnosing and treating this cancer and the exciting potential for personalized therapies tailored to these molecular discoveries.
Michael Fritz, MD, Director of the Section of Facial Plastic and Reconstructive Surgery at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the approaches to the classification and management of mandibular osteoradionecrosis (ORN). Listen as Dr. Fritz shares insights into the classification and treatment of ORN, including the role of PENTO therapy and the groundbreaking anterolateral thigh rescue flap technique, highlighting the importance of early intervention and how multidisciplinary collaboration can improve patient outcomes.
The Cancer Advances podcast is joined by hematologists Sandra Mazzoni, DO and Shahzad Raza, MD to discuss the latest advancements in multiple myeloma treatment. Listen as they explore the evolving role of CAR-T cell therapy, bispecific antibodies, and autologous stem cell transplants and how they are changing the multiple myeloma treatment landscape.
Kevin Elias, MD, the Lilli and Seth Harris Endowed Chair for Ovarian Cancer at Cleveland Clinic, joins the Cancer Advances podcast to discuss the challenges of trying to detect ovarian cancer early and the need for better predictive tools. Listen as Dr. Elias talks about the MiDe Study, which aims to identify high-risk women through microRNA-based blood tests, potentially transforming ovarian cancer screening and prevention.
Gloria Gonzalez, MD, Pediatric Surgeon and Director of Pediatric Surgical Oncology, joins the Cancer Advances podcast to provide her insights on advanced surgical techniques for neuroblastoma. Listen as Dr. Gonzalez explains the complexities of neuroblastoma, the use of 3D printing in preoperative planning and 3D image-guided surgery, and the emerging role of fluorescent-guided surgery.
The Cancer Advances podcast is joined by the Chair of the Palliative and Supportive Care Department, Laura Shoemaker, DO, and Integrative Medicine Specialist, Naoki Umeda, MD, to talk about Cleveland Clinic’s Integrative Oncology Program. Listen as they share how combining evidence-based complementary therapies, such as acupuncture and lifestyle medicine, with conventional cancer treatment can help alleviate symptoms, enhance patients' quality of life, and improve outcomes.
Paolo Caimi, MD, Associate BMT Director for Cell Therapy at Cleveland Clinic Cancer Institute, joins the Cancer Advances podcast to discuss the latest advancements in immunotherapy for aggressive lymphomas. Listen as Dr. Caimi talks about the potential of bispecific antibody combinations, including early-phase findings on glofitamab plus ICE chemotherapy for relapsed and refractory diffuse large B-cell lymphoma.
Vice Chair of the Center for Immunotherapy & Precision Immuno-Oncology, J. Joseph Melenhorst, PhD, joins the Cancer Advances Podcast to discuss the potential of CAR T-cell therapy for chronic lymphocytic leukemia (CLL). Listen as Dr. Melenhorst explains how advancements in cell therapy are overcoming challenges like T cell exhaustion, improving response rates, and how novel approaches could improve treatment outcomes.
Moshe Ornstein, MD, MA, a Genitourinary Medical Oncologist joins the Cancer Advances podcast to talk about intermittent therapy for metastatic renal cell carcinoma (mRCC). Listen as Dr. Ornstein explores the evolution of treatment options, from cytokine and targeted therapies to immunotherapy, and as he delves into the promising concept of treatment breaks to improve patient outcomes.
Medical Oncologist in the Lymphoid Malignancies Division, Taylor Brooks, MD, joins the Cancer Advances podcast to discuss real-world data on bispecific antibodies for relapsed or refractory large B-cell lymphomas that was presented at the 2024 American Society of Hematology (ASH) Annual Meeting. Listen as Dr. Brooks shares insights into efficacy, safety, and challenges patients face outside clinical trial parameters, and how these therapies are reshaping treatment approaches.
Lukas Nystrom, MD, Orthopaedic Oncology Surgeon and a Co-Director of the Sarcoma Program at Cleveland Clinic joins the Cancer Advances Podcast to talk about the advancements in custom 3D-printed implants for pelvic sarcoma reconstruction. Listen as Dr. Nystrom explains how these personalized implants are transforming sarcoma care by enhancing precision during tumor resections, offering tailored solutions for complex pelvic reconstructions and improving patient outcomes.
Ruth Keri, PhD, Associate Director for Basic Research at Case Comprehensive Cancer Center and Professor of Cancer Biology at Cleveland Clinic, returns to the Cancer Advances Podcast to share the latest advancements in targeting YES1 protein to treat triple-negative breast cancer (TNBC). Listen as Dr. Keri discusses how YES1 impacts chemotherapy resistance, tumor growth, and EGFR inhibition, uncovering promising therapeutic opportunities and the potential clinical trials to improve outcomes for patients facing this aggressive cancer.
The Cancer Advances podcast is joined by Director of Pediatric Radiation Oncology, Erin Murphy, MD, and resident physician, Jenna Kocsis, MD, to share their latest findings on the use of stereotactic body radiation therapy (SBRT) to treat recurrent osteosarcoma. Listen as they discuss the challenges of managing this radio-resistant tumor, including its use in complex cases involving the spine and epidural space, and explore emerging techniques that have the potential to transform cancer care for young patients while reducing long-term side effects.
Theresa Callard-Moore, PhD, LSW, a psychotherapist and certified sex therapist at Cleveland Clinic, joins the Cancer Advances podcast to shed light on the often-overlooked topic of sexual health in cancer patients. In this episode, Dr. Callard-Moore emphasizes the importance of initiating open conversations about sexual health early in the care journey. She also shares valuable insights, practical strategies, and resources to help patients feel heard and supported to address their concerns.
Ali Azka, MD, medical oncologist specializing in breast cancer joins the Cancer Advances podcast to talk about her new research on ESR1 mutations and the PI3-kinase pathway's impact on the effectiveness of elacestrant in treating advanced hormone receptor-positive, HER2-negative breast cancer. This study, presented at the 2024 San Antonio Breast Cancer Symposium (SABCS), highlights the role of real-world data, optimal treatment sequencing, and the evolving landscape of targeted therapies. Tune in as Dr. Azka explores these advancements and their potential to improve patient outcomes.
Chair of the Department of Colorectal Surgery, Director of the Weiss Center for Hereditary GI Neoplasia and Center for Young Onset Colorectal Cancer, David Liska, MD, joins the Cancer Advances Podcast to discuss Cleveland Clinic's integrated program for young people with cancer. Listen as Dr. Liska explains the rise in early-onset cancers, potential factors, and the unique challenges young patients face. Learn how this comprehensive program leverages multidisciplinary care, advanced research, and innovative technology to improve outcomes and survivorship for young cancer patients.
Beth Faiman, PhD, CNP, a Nurse Practitioner and Clinical Researcher at Cleveland Clinic specializing in multiple myeloma, joins the Cancer Advances podcast to discuss updates in managing relapsed and refractory multiple myeloma. Listen as Dr. Faiman talks about advancements in treatment, including proteasome inhibitors, monoclonal antibodies, and bispecific antibodies, which improve both survival rates and the quality of life for patients. She also highlights key research presented at the International Myeloma Society meeting, focusing on CAR T-cell therapy, transplant eligibility criteria, and personalized treatment planning.
Michael Kelly, MD, PhD, a pediatric hematologist and oncologist at Cleveland Clinic Children's, joins the Cancer Advances podcast to discuss innovative care for vascular anomalies. In this episode, Dr. Kelly explains how they are exploring advanced treatments, including clinical trials using cancer medications to address these non-cancerous conditions, the impact of somatic mutations, and the evolving role of genetic research. Discover the latest advances and how these efforts aim to improve both the quality of life and outcomes for patients facing these rare and challenging conditions.
Inpatient Director of the Cellular and Immunotherapy Service, John Molina, MD, EdM, joins the Cancer Advances podcast to talk about the launching of the Cellular and Immunotherapy Service to manage the growing number of patients receiving cellular therapies like CAR-T and bispecific antibodies. Listen as Dr. Molina share insights on the protocols that help identify and mitigate toxicities early, reducing ICU stays and enhancing patient outcomes with the long-term goal of transitioning more patients to outpatient management where possible.
Josephine K. Dermawan, MD, PhD, a soft tissue pathologist at Cleveland Clinic joins the Cancer Advances podcast to discuss the development of novel genomic risk stratification models for soft tissue and uterine leiomyosarcomas. Given the complexity and variety of sarcomas, accurately identifying subtypes is key to effective treatment. Listen as Dr. Dermawan explains the challenges of risk stratification and how genomic profiling enhances our ability to predict tumor behavior, leading to more precise treatment decisions.
Chair of the Department of Gastroenterology, Hepatology and Nutrition, Michelle Kang Kim, MD, PhD, joins the Cancer Advances podcast to discuss neuroendocrine tumors and carcinoid heart disease. Listen as Dr. Kim shares her expertise on this rare but increasingly prevalent type of cancer, the complexities of managing carcinoid heart disease, a condition seen in patients with metastatic neuroendocrine tumors, and the benefits of multidisciplinary care in treatment planning.
Breast Medical Oncologist, Erin Roesch, MD, joins the Cancer Advances podcast to discuss endocrine therapy for breast cancer in young patients. Listen as Dr. Roesch explains the key differences in treatment for premenopausal women, including the use of tamoxifen, ovarian suppression, and aromatase inhibitors.
Joshua Arbesman, MD, Dermatologist and Director of the Pigmented Lesion Clinic at Cleveland Clinic, joins the Cancer Advances podcast to talk about the genetic risks of melanoma. Listen as Dr. Arbesman delves into the inherited predispositions for melanoma, highlights key findings from his research on identifying high-risk patients and explains how genetic testing can help in early detection and personalized treatment.
Zeina Nahleh, MD, Cancer Center Director and Regional Chair of Hematology Oncology at Cleveland Clinic in Florida joins the Cancer Advances Podcast to discuss the latest breakthroughs in treating brain metastasis in breast cancer patients. Listen as Dr. Nahleh shares insights into the challenges of managing this complex condition, highlights key findings from her recent study, and emphasizes the critical role of combining local and systemic therapies. Discover what the future holds with emerging treatments and how they may improve patient outcomes in this evolving field.
Gregory Videtic, MD, Director of the Thoracic Radiation Oncology Program at Cleveland Clinic, joins the 200th episode of the Cancer Advances podcast to talk about neuroprotection in patients with small cell lung cancer. Listen as Dr. Videtic explains the findings of the NRG CC003 trial, which examined how hippocampal-sparing radiation could minimize memory-related side effects while maintaining cancer control.
The Cancer Advances podcast is joined by Ofer Reizes, PhD, the Laura J. Fogarty Endowed Chair for Uterine Cancer Research, and Roberto Vargas, MD, Gynecologic Oncologist and Program Director for the Gynecologic Oncology Fellowship to discuss their research on targeting CD55 to combat chemoresistance in ovarian cancer patients. Listen as they insights into the mechanisms behind chemoresistance, the challenges it presents in treatment, and the potential for innovative therapies to transform patient outcomes.
Arun D. Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, returns to the Cancer Advances podcast to discuss iris melanoma. Listen as Dr. Singh talks about the unique characteristics of this rare eye cancer, the latest advancements in diagnosis and treatment, including cutting-edge imaging techniques and the potential of machine learning. Tune in for this insightful discussion on this rare type of melanoma.
The Cancer Advances podcast is joined by third-year internal medicine resident, Heya Batah, MD, and hematologist and medical oncologist, Moaath Khader Mustafa Ali, MD, MPH to discuss the latest findings on the combination of atezolizumab with carboplatin and etoposide in treating extensive stage small cell lung cancer. Listen as they talk about the real-world data presented by Dr. Batah at ASCO, focusing on the impact of atezolizumab on overall survival and progression-free survival compared to traditional chemotherapy alone.
Shlomo Koyfman, MD, Director of Head and Neck and Skin Radiation at Cleveland Clinic, joins the Cancer Advances podcast to talk about the latest ASCO clinical practice guidelines for managing osteoradionecrosis, a potential complication due to radiation therapy. Listen as Dr. Koyfman discuss how the new guidelines are designed to enhance the prevention, early detection, and management of osteoradionecrosis. He shares insights into how these guidelines can be put into practice, and the impact of these new strategies on patient care and survivorship.
Thach-Giao Truong, MD, Director of the Melanoma Program at Cleveland Clinic, joins the Cancer Advances podcast to discuss Tumor-Infiltrating Lymphocyte (TIL) therapy. This cutting-edge, personalized cancer treatment utilizes a patient's immune cells to target and destroy tumors. Listen as Dr. Truong provides insights into the science behind TIL therapy, its advantages, and its potential to revolutionize treatment for patients with resistant melanoma and other challenging cancers.
Lily Wang, PhD, from the Department of Translational Hematology Oncology Research at Cleveland Clinic, joins the Cancer Advances Podcast to dive into her research on VISTA and LRIG1 interactions. Dr. Wang, an expert in immune mechanisms within cancer, discusses her lab's innovative work on these immune checkpoint proteins and their potential to overcome current treatment limitations. Discover how targeting the VISTA-LRIG1 axis could offer new strategies for tackling resistant tumors and improving patient outcomes.
Urologic Oncologist, Zeyad Schwen, MD, joins the Cancer Advances podcast to discuss prostate cancer and genomics. Learn about the latest advancements in genomic testing, its impact on diagnosis and treatment, and how these innovations shape personalized care in oncology. Dr. Schwen shares insights on the practical applications of genomics in prostate cancer, discusses ongoing research, and explores the potential future of cancer diagnostics.
Lukas Delasos, DO, Medical Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to talk about the ADRIATRIC study. Dr. Delasos shares his insights on small cell lung cancer, detailing its aggressive nature, current treatment paradigms, and the promising results from the ADRIATIC study involving durvalumab as a consolidation therapy.
The Cancer Advances podcast is joined by Palliative Medicine physicians, Renato Samala, MD and Chirag Patel, MD to discuss the use of scrambler technology to treat neuropathic symptoms in cancer patients. Traditional medications for neuropathic symptoms caused by cancer treatments can be ineffective and often have side effects. Scrambler technology, which uses electrical signals to reprogram nerve signals, offers an innovative alternative. Listen as Dr. Samala and Dr. Patel explain the potential benefits of scrambler therapy, its application, patient selection, and prospects for better access and research on long-term outcomes.
Joel Cardenas Goicoechea, MD, MBA, a Gynecologic Oncologist at Cleveland Clinic Weston Hospital in Florida, joins the Cancer Advances podcast to discuss the benefits of robotic cytoreductive surgery combined with laparoscopic HIPEC for ovarian cancer. Listen as Dr. Cardenas explains how this innovative approach offers lower complication risks, reduced blood loss, and shorter hospital stays than traditional open surgery. Tune in to learn how these advancements enhance patient outcomes and quality of life in the treatment of ovarian cancer.
Gynecologic Oncologist, Peter Rose, MD, joins the Cancer Advances podcast to share insights on an exciting new clinical trial investigating adoptive immunotherapy for ovarian cancer. The trial investigates personalized T-cell therapies and their potential to transform treatment outcomes. Discover how this groundbreaking approach offers new hope in the battle against advanced ovarian cancer.
Holly Pederson, MD, an Oncologist and member of the medical breast team at Cleveland Clinic, joins the Cancer Advances podcast to discuss her research on using polygenic risk scores to predict early onset triple-negative breast cancer in Black women. While polygenic risk scores have shown promise in predicting breast cancer risk, they have mainly been tested in European women and are less accurate for other ancestries. Listen as Dr. Pederson talks about the complexities of genetic risk factors across different ancestries and how these scores can revolutionize early detection and prevention strategies.
The Cancer Advances podcast is joined by Wen Wee Ma, MBBS, Director of the Novel Cancer Therapeutics Center, and Lucy Boyce Kennedy, MD, Director of the Oncology Pharmacovigilance Clinic. Listen as they discuss how this new Oncology Pharmacovigilance Clinic enhances patient care by addressing complex toxicities and side effects from immunotherapy treatment, and integrates specialists from rheumatology, endocrinology, pulmonology and more.
Nima Almassi, MD, a Urologic Oncologist at Cleveland Clinic, joins the Cancer Advances Podcast to discuss managing non-muscle-invasive bladder cancer with variant histologies. Listen as Dr. Almassi talks about effectiveness of intravesical therapy, the importance of specialized pathology reviews, and the potential need for early cystectomy in aggressive variants.
Roberto Vargas, MD, gynecologic oncologist at Cleveland Clinic, joins the Cancer Advances Podcast to discuss adding immunotherapy to chemotherapy for endometrial cancer. Listen as Dr. Vargas sheds light on recent studies demonstrating that adding checkpoint inhibitors to standard chemotherapy could notably lower the risk of cancer recurrence in patients with MMR-deficient or MSI-high tumors and the potential of genomic-based therapies for endometrial cancers.
Erin Murphy, MD, Director of Pediatric Radiation Oncology at Cleveland Clinic, joins the Cancer Advances Podcast to discuss stereotactic radio surgery (SRS) for adolescent and young adult brain and spine tumors. Listen as Dr. Murphy highlights the benefits of SRS for younger patients, including shorter treatment intervals, less impact on daily routine and recovery, and the ability to continue with school during treatment.
The Cancer Advances podcast is joined by Ofer Reizes, PhD, the Laura J. Fogarty Endowed Chair for Uterine Cancer Research, and Justin Lathia, PhD, Melvin H. Burkhardt Endowed Chair for Neuro-Oncology Research, Scientific Director of the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, and the Vice Chair of the Department of Cardiovascular and Metabolic Sciences at Cleveland Clinic's Lerner Research Institute to discuss their research on peptide therapy as a targeted treatment for triple negative breast cancer. Listen as they explain their collaborative efforts to develop therapeutic peptides that disrupt cancer stem cell programs, the process of their work, and the potential for expanding peptide therapy to other cancer types.
Young-onset colorectal cancer is becoming more common, and the microbiome could be playing a role in the increase of cases. Alok Khorana, MD, Director of the Gastrointestinal Malignancies Program at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to discuss this issue. Listen as Dr. Khorana highlights his research on the link between changes in the microbiome and the development and progression of colorectal cancer in younger patients. He also discusses the ongoing metabolomic analysis and investigations.
The Cancer Advances podcast is joined by colorectal surgeons, I. Emre Gorgun, MD, Vice Chair of the Department of Colorectal Surgery, and Joshua Sommovilla, MD, Director of the Colon Cancer Tumor Board, to talk about organ preservation in rectal cancer treatment. Listen as they discuss the rising use of neoadjuvant therapy to shrink tumors before surgery, endoluminal procedures, and the importance of close surveillance and follow-ups for patients.
Shilpa Gupta, MD, Director of the Genitourinary Oncology Program at Cleveland Clinic Cancer Institute, provides an overview of the clinical trial of enfortumab vedotin and pembrolizumab in untreated advanced urothelial cancer. Listen as Dr. Gupta talks about the exciting results of the trial, which showed that the combination therapy was effective for both cisplatin-eligible and cisplatin-ineligible patients. She also highlights the future studies that are being conducted to explore the use of the therapy in the neoadjuvant setting.
Anjali Advani, MD, Director of the Inpatient Leukemia Unit at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the innovations in acute lymphoblastic leukemia (ALL). While chemotherapy has traditionally been the go-to treatment, advancements like blinatumomab and CAR-T cell therapy are reshaping care. Listen as Dr. Advani discusses the challenges and considerations in choosing these therapies, CAR-T re-challenge potential, and the future directions in ALL treatments.
Halle Moore, MD, Director of Breast Medical Oncology at Cleveland Clinic, joins the Cancer Advances Podcast to explore the safety of pregnancy after breast cancer with BRCA mutations. In the episode, Dr. Moore emphasizes the importance of early conversations regarding reproductive goals and available fertility preservation strategies for breast cancer patients while maintaining an effective cancer treatment. Despite limited data on this topic, Dr. Moore highlights positive outcomes observed in retrospective studies.
Hematology oncologist, Allison Winter, MD, joins the Cancer Advances podcast to discuss the latest innovations in treating chronic lymphocytic leukemia (CLL). Listen as she explains how the treatment for CLL has evolved over the past decade, with a shift towards using novel therapies such as BTK inhibitors and venetoclax, as well as the concept of time-limited therapy. Dr. Winter also shares insights into ongoing clinical trials like the MAJIC trial, which compares different treatment combinations.
Alison Ibsen, Senior Director for Cancer Programming, joins the Cancer Advances Podcast to talk about the role of cancer programming to enhance cancer patient care. Cancer programming brings together various experts involved in the treatment of a specific cancer to promote multidisciplinary care to help improve outcomes. Listen as Alison elaborates on the program development, its emphasis on creating effective care pathways, and the importance of collaboration across different locations and departments within Cleveland Clinic.
Michael Valente, DO, Program Director for the Colorectal Surgery Residency Program, and Director of the Peritoneal Surface Malignancy Program & Center for Metastatic Colorectal Cancer at Cleveland Clinic, joins the Cancer Advances Podcast to discuss advances in stage 4 colon cancer treatment. Listen as Dr. Valente highlights the significant improvements in outcomes for late stage colon cancer patients due to the recent advancements in surgery, chemotherapy, and immunotherapy. During the episode, he stresses the importance of early screening for colon cancer and the potential for personalized treatments and precision medicine in the future.
The Cancer Advances podcast is joined by surgeon, Federico Aucejo, MD, Director of the Liver Tumor Clinic, and medical GI oncologist, Bassam Estfan, MD, Co-Director of the Liver Tumor Program, to discuss the use of ctDNA screening in colorectal cancer with liver metastases. Tune in to learn about the current state of disease management and the potential of ctDNA testing to guide treatment decisions and monitor disease progression.
Michelle Kuznicki, MD, a gynecologic oncologist, joins the Cancer Advances podcast to talk about fertility-sparing surgery for early-stage cervical cancer. Drawing from her systematic review of oncologic and pregnancy outcomes associated with various surgical techniques, Dr. Kuznicki talks about the shift towards less invasive procedures, highlighting the importance of aligning surgical options with the patient's reproductive goals.
Hematologist, Shahzad Raza, MD, joins the Cancer Advances Podcast to talk about the evolving understanding of smoldering multiple myeloma. Listen as Dr. Raza discusses the challenges in risk stratification, complexities of treatment decisions, and the need for close patient monitoring and education.
The Cancer Advances podcast is joined by Dr. Eileen Slavin, DO, a physiatrist specializing in oncology rehabilitation, to discuss the important role of oncology rehabilitation services in cancer recovery. Listen as Dr. Slavin explains the significance of prehabilitation, collaboration with physical therapy and palliative care, and how the field is evolving.
Brian T. Hill, MD, PhD, Co-Director of the Lymphoid Malignancies Program at Cleveland Clinic, joins the Cancer Advances Podcast to discuss advances in mantle cell lymphoma. Listen as Dr. Hill highlights current treatments and how promising strategies like BTK inhibitors and CAR T-cell therapy are being used. He also addresses challenges such as TP-53 mutations, discusses potential advancements, and emphasizes the importance of individualized treatment approaches.
Mailey Wilks, CNP, APP manager at the Taussig Cancer Center, and Heather Koniarczyk, CNP, Director of Advanced Practice, join the Cancer Advances Podcast to discuss the implementation and success of a Virtual Anemia Clinic. The clinic was developed to address the increased demand for anemia consult requests and aim to reduce average wait times. Listen as they explain how the virtual platform allows for convenient and timely consultations, a 70% retention rate, and the plans for future expansions.
Associate Director of the Gamma Knife Center at Cleveland Clinic, Samuel Chao, MD, joins the Cancer Advances Podcast to talk about the evolution of gamma knife technology. Listen as Dr. Chao takes us through gamma knife's history, the current advantages and considerations, as well as potential future advances in the field.
Shauna Campbell, DO, Radiation Oncologist and Co-Director of the Cleveland Clinic Sarcoma Program joins the Cancer Advances podcast to discuss ultra-hypofractionated radiotherapy for soft tissue sarcoma. Listen as Dr. Campbell explains the advancements, outcomes, and considerations of this innovative approach, referencing her meta-analysis that was presented at the American Society of Radiation Oncology (ASTRO) 2023 Annual Meeting.
Peter Mazzone, MD, MPH, pulmonologist and Section Leader for Thoracic Oncology at Cleveland Clinic, joins the Cancer Advances podcast to discuss the development of blood tests to screen for lung cancer. Listen as Dr. Mazzone explains the intricacies of DNA analysis within these tests, offering insights into their potential to detect lung cancer and alleviate barriers to screenings.
Sudha Amarnath, MD, Co-Director of the Gynecologic Cancer Program, joins the Cancer Advances podcast during Cervical Cancer Awareness Month to share insights on how to improve the quality of care for cervical cancer patients. Listen as Dr. Amarnath talks about the metrics considered for improvement, including tumor board presentations, pathology reviews, imaging protocols, and socioeconomic support. With a focus on multidisciplinary care, Dr. Amarnath explains the implementation of a weekly cervical cancer huddle at Cleveland Clinic to optimize the continuum of care.
Laura Shoemaker, DO, Chair of Palliative and Supportive Care at Cleveland Clinic, joins the Cancer Advances podcast to discuss navigating difficult conversations in the field of oncology. Listen as Dr. Shoemaker shares valuable insights into the essential elements for handling hard discussions, including empathy, validating emotions, and the importance of fostering a relationship built on trust.
Section Chief of Reproductive Endocrinology and Infertility at Cleveland Clinic's Fertility Center, Mindy Christianson, MD, MBA, joins the Cancer Advances podcast to discuss uterine-focused fertility preservation. Dr. Christianson talks about the uterine damage that can be caused by pelvic radiation and explains uterine transposition as a solution. During the episode, Dr. Christianson provides details on the complex surgery, its success stories, and emphasizes the significance of a comprehensive, multidisciplinary approach to fertility preservation.
Jacob Miller, MD, a Radiation Oncologist at Cleveland Clinic, joins the Cancer Advances podcast to share his insights on nasopharyngeal carcinoma (NPC) screening and his trial presented at the American Society of Radiation Oncology (ASTRO) 2023 Annual Meeting. NPC is rare in the United States but prevalent in Southern China, primarily caused by the Epstein-Barr virus (EBV). Listen as Dr. Miller explains his screening trial that resulted in earlier-stage diagnoses and improved outcomes, as well as lessons from this research that may inform screening strategies for other cancers.
The Cancer Advances podcast is joined by Shahzad Raza, MD, a hematologist at Cleveland Clinic Cancer Center, discussing eye toxicities linked to cancer treatments. Listen as Dr. Raza talks about his study examining real-world experiences compiling eye toxicities from several anticancer drugs. During the podcast, he emphasizes the importance of the early involvement of ophthalmologists in patient care and incorporating ophthalmology exams in clinical trials.
Emre Gorgun, MD, colorectal surgeon and Vice Chair of Colorectal Surgery at Cleveland Clinic, joins the Cancer Advances podcast to talk about his study from Digestive Disease Week (DDW) on predicting complete responses to total neoadjuvant therapy (TNT) in patients with locally advanced rectal cancer. Listen as Dr. Gorgun share insights on success rates of TNT, the factors influencing complete response, patient surveillance, and the potential use of immunotherapy.
Faiz Anwer, MD, a hematologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss CRISPR, a gene-editing technology. Listen as Dr. Anwer highlights CRISPR's advantages over traditional cellular therapies, the challenges of off-target effects, and its future in solid tumor treatment.
Medical Oncologist and Co-Director of the Lung Cancer Program at Cleveland Clinic, Nathan A. Pennell, MD, PhD joins the Cancer Advances podcast to discuss the study he and his team conducted exploring the potential benefits of transitioning from single-gene testing to next-generation sequencing (NGS). Listen as Dr. Pennell explains the pivotal role genomic testing has in treating lung cancer and the barriers to widespread NGS testing.
Radiation Oncologist and Co-Director of the Comprehensive Breast Cancer Program at Cleveland Clinic, Chirag Shah, MD, joins the Cancer Advances podcast to discuss his study on the innovative use of CPAP (Continuous Positive Airway Pressure) machines in combination with radiation therapy. Listen as Dr. Shah explains how using CPAP machines in radiation therapy has been shown to reduce radiation-related toxicities in breast and lung cancer patients.
Ruth Keri, PhD, Associate Director for Basic Research at the Case Comprehensive Cancer Center and Professor of Cancer Biology at Cleveland Clinic, joins the Cancer Advances Podcast to talk about her research on a promising new target for treating triple-negative breast cancer, YES1 inhibitors. Listen as Dr. Keri shares the potential of YES1 inhibitors in improving the effectiveness of chemotherapy and the clinical trials that are underway to assess the safety and effectiveness of these inhibitors.
Suneel Kamath, MD, a hematologist and medical oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss his research from the American Society of Clinical Oncology (ASCO) 2023 annual meeting on the metabolomic differences between young onset colorectal cancer (yoCRC) and average onset colorectal cancer (aoCRC). Listen as Dr. Kamath talks about the challenges associated with early detection, the evolving landscape of screening guidelines, potential contributing factors to the rise of yoCRC, and the role of metabolomics in unraveling the complexities of colorectal cancer.
We kick off Breast Cancer Awareness Month with radiologist Laura Dean, MD, who discusses the incorporation of artificial intelligence (AI) into mammography for breast cancer screening and detection. Listen in as our host, Dr. Dale Shepard, talks with Dr. Dean about the new AI algorithms that have improved the accuracy of mammogram interpretations. Dr. Dean explains digital breast tomosynthesis (3D mammography), the benefits of AI in reducing callback rates, and more.
Omar Mian, MD, PhD, radiation oncologist, and physician scientist, joins the Cancer Advances Podcast to talk about emerging molecular biomarkers for genitourinary cancers. During the episode, Dr. Mian explains the multidisciplinary approach required for effective biomarker utilization, the success of prognostic and predictive biomarkers, and his ongoing research on germline polymorphisms and the use of PET scans with PSMA tracers.
Urologic Oncologist, Zeyad Schwen, MD, joins the Cancer Advances podcast to discuss focal therapies for prostate cancer. Dr. Schwen provides insights into the selection process for candidates and explores various focal therapy methods like NanoKnife and HIFU (High-Intensity Focused Ultrasound). Listen as Dr. Schwen explains the benefits, limitations, and ongoing clinical trials of these treatments.
Director of the Novel Cancer Therapeutics Center, Wen Wee Ma, MBBS, joins the Cancer Advances podcast to talk about the Novel Cancer Therapeutics Center. Listen as Dr. Ma delves into the center's mission and role to help bring the latest innovative treatments to patients, expanding clinical trial accessibility across different regions, and the shift from traditional drug-focused approaches to multimodality treatments.
The Cancer Advances podcast kicks off Prostate Cancer Awareness Month with urologic oncologist Zeyad Schwen, MD, to talk about active surveillance. Listen as Dr. Schwen explains the history of prostate cancer diagnosis, the importance of accurate risk assessment to prevent overtreatment, the significance of PSA testing, and the evolving role of advanced imaging techniques.
The Cancer Advances podcast is joined by Justin Lathia, PhD, Melvin H. Burkhardt Endowed Chair for Neuro-Oncology Research, Scientific Director of the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, and the Vice Chair of the Department of Cardiovascular and Metabolic Sciences at Cleveland Clinic's Lerner Research Institute to talk about his study on mitochondria transfer for glioblastoma. Listen as Dr. Lathia shares the complexity of glioblastomas, the challenges in treating it, and the potential of mitochondria transfer as a communication process.
Mr. Stewart Kohl, co-CEO of the Riverside Company, a member of the board of directors at Cleveland Clinic, and founder of VeloSano joins the Cancer Advances podcast to celebrate 10 years of Cleveland Clinic's cancer research fundraising initiative, VeloSano. Listen as Mr. Kohl talks about the journey of VeloSano's 10-year impact on advancing cancer research.
In this episode of Cancer Advances, host Dale Shepard, MD, PhD, talks with Tatiana Byzova, PhD, a staff member in the neurosciences program, about the significance of thrombosis in cancer patients along with current therapy options. Listen as they discuss the challenges of balancing anticoagulant therapy, and Dr. Byzova's research on tumor-platelet interactions and the role of vesicles in thrombus formation. This thought-provoking discussion sheds light on potential treatment options and the importance of understanding the intricate relationship between cancer and thrombosis.
Gary Schwartz, MD, Director of the Case Comprehensive Cancer Center, and a medical oncologist who specializes in sarcoma joins the Cancer Advances podcast to discuss his goal of improving cancer care not just in Cleveland, but beyond. Listen as he talks about his vision for seamless integration of science and clinical practice and fostering rapid translation from bench to bedside and more.
In this episode of the Cancer Advances podcast, Dale Shepard, MD, PhD is joined by Shlomo Koyfman, MD, Director of Head and Neck and Skin Radiation at Cleveland Clinic to discuss the use of stereotactic body radiation therapy (SBRT) for head and neck cancer treatment. Dr. Koyfman shares insights from his experience highlighting the role of SBRT in re-irradiation cases as a primary therapy option. This informative conversation sheds light on the innovative techniques and advancements in radiation oncology that are improving outcomes for patients with head and neck cancer.
Zachary D. Burke, MD, an orthopedic oncologist specializing in pediatric sarcomas, joins the Cancer Advances Podcast to talk about limb sparing surgical techniques for pediatric sarcoma. Listen as Dr. Burke explains the unique challenges posed by pediatric cases, the advancements being made in the field, and research efforts aimed at improving sarcoma treatments.
Arun D. Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, joins the Cancer Advances podcast to discuss metastases to the eye. Listen as Dr. Singh talks about the common types of cancer that metastasize to the eye, symptoms, treatment options, and the importance of looking out for metastases in patients.
Adriana Alveraz, MD, regional oncologist and palliative medicine physician, joins the Cancer Advances Podcast to talk about cancer-related anorexia and cachexia syndrome. Listen as Dr. Alveraz explains the challenges in diagnosing this syndrome, what physicians should pay attention to, as well as the importance of palliative care with cancer treatment.
Joseph Scharpf, MD, FACS, Director of Head and Neck Endocrine Surgery at the Cleveland Clinic Head and Neck Institute, and Emrullah Yilmaz, MD, PhD, an oncologist at Cleveland Clinic Taussig Cancer Institute, specializing in head and neck cancers, join the Cancer Advances podcast to discuss their study that provides insights to treatment strategies and tumor characteristics of anaplastic thyroid cancer. Listen as Dr. Scharpf and Dr. Yilmaz discuss patients with BRAF mutations and Cleveland Clinic's collaborative approach for thyroid cancer care.
Lukas Nystrom, MD, an orthopedic surgeon at Cleveland Clinic specializing in musculoskeletal oncology, joins the Cancer Advances podcast to talk about the management of soft tissue sarcoma in adults. Listen as Dr. Nystrom talks about the misconceptions and the multidisciplinary care that is needed to treat this rare cancer.
Jack Khouri, MD, hematologist oncologist at Cleveland Clinic Cancer Center, who specializes in rare plasma cell disorders joins the Cancer Advances podcast to discuss ide-CEL CAR T-cell therapy and its effectiveness in multiple myeloma patients. Listen as Dr. Khouri talks about the KarMMA trial and his retrospective study.
Sandra Mazzoni, DO, a hematologist at Cleveland Clinic Taussig Cancer Institute joins the Cancer Advances podcast to talk about monoclonal gammopathy of undetermined significance, known as MGUS. Listen as Dr. Mazzoni talks about this abnormal protein and explains when we can still effectively treat patients before it hits all the criteria for becoming multiple myeloma.
Radiation Oncologist, Physician Scientist, and Founding Director of the Center for Hyperthermia at Cleveland Clinic, Jennifer Yu, MD, PhD, joins the Cancer Advances podcast to discuss hyperthermia therapy, which uses heat to destroy cancer cells and shrink tumors. Listen as Dr. Yu explains how this therapy works; and how it helps radiation and chemotherapy treatments become more effective for patients.
The Cancer Advances podcast is joined by Abhay Singh, MD, MPH, a physician with the Department of Hematology and Medical Oncology at Cleveland Clinic to talk about his study, which aimed to identify risk factors for secondary malignancy in breast cancer survivors. This study was presented at the American Society of Hematology (ASH) 2022 annual meeting. Listen as Dr. Singh explains how he explored the different risk factors, such as G-CSF exposure, how the CHIP Clinic might be able to monitor patients, and the long-term goal to figure out which therapies patients should try to avoid.
Alex A. Adjei, MD, PhD, Chair of Cleveland Clinic Taussig Cancer Institute, joins the Cancer Advances podcast to discuss the new Novel Therapeutics Clinic. Listen as Dr. Adjei shares the importance of novel cancer therapetuics, how the clinic is structured, and his hopes of having multiple treatment options for every cancer.
Arun D. Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, and Stacey Zahler, DO, a pediatric hematologist-oncologist at Cleveland Clinic Children's join the Cancer Advances podcast to discuss retinoblastoma. Listen as they discuss this unique children's eye cancer, the treatment options available, and the genetic counseling we have at Cleveland Clinic.
Emrullah Yilmaz, MD, PhD, an oncologist at Cleveland Clinic Taussig Cancer Institute specializing in head and neck cancers, joins the Cancer Advances podcast to discuss new ASCO guidelines for recurrent and metastatic head and neck cancers. Listen as Dr. Yilmaz explains how the guidelines focus on biomarkers, tumor mutation burdens, and how they will impact patient care.
Aaron Gerds, MD, MS, a hematologist in Cleveland Clinic Cancer Center’s Leukemia and Myeloid Disorders Program and Deputy Director for Clinical Research at the Taussig Cancer Institute joins the Cancer Advances podcast to talk about the MOMENTUM trial that was presented at the American Society of Hematology (ASH) 2022 annual meeting. Listen as Dr. Gerds discusses myelofibrosis, the differences between the trial results from 24 to 48 weeks, and the exciting new approaches that are coming to the field.
Hermann Kessler, MD, PhD, a senior colorectal surgeon in the Department of Colorectal Surgery, joins the Cancer Advances podcast to talk about the benefits of a complete mesocolic excision (CME) for patients with colon cancer. Listen as Dr. Kessler talks about improving survival and local recurrence rates, the importance of screening programs, and incorporating different modalities into surgery.
The Cancer Advances podcast is joined by Kate Eshleman, PsyD, a pediatric psychologist in the Center for Pediatric Behavioral Health at Cleveland Clinic Children's to talk about the mental health of children and teenagers with cancer. Listen as Dr. Eshleman discusses the Cleveland Clinic Children's survivorship program, what medical professionals should watch out for, and how to assist patient families.
Chair of the Department of Gastroenterology, Hepatology, and Nutrition, Michelle Kang Kim, MD, PhD, joins the Cancer Advances podcast to discuss neuroendocrine tumors. Listen as Dr. Kim talks about creating a database of biomarker studies, the use of DOTATATE PET CT imaging, and the collaborative, multi-disciplinary approach taken at Cleveland Clinic to treat neuroendocrine tumors.
Christopher Weight, MD, Center Director of Urologic Oncology at Cleveland Clinic joins the Cancer Advances podcast to discuss using artificial intelligence to diagnose kidney cancer. Listen as Dr. Weight explains the progress we have made with imaging-generated software and a fully automated equivalent nephrometry score.
Breast Medical Oncologist at Cleveland Clinic Taussig Cancer Institute, Megan Kruse, MD, joins the Cancer Advances podcast to discuss the differences in the clinical management of invasive lobular breast cancer (ILC) and invasive ductal breast cancer (IDC). Listen as Dr. Kruse discusses the challenges of diagnosing, re-evaluating treatment options, and using genomic data to see different trends for lobular and ductal breast cancer.
Ali Aminian, MD, Director of Cleveland Clinic's Bariatric and Metabolic Institute, joins the Cancer Advances podcast to talk about his study on how bariatric surgery can significantly lower a patient's risk of developing obesity-related cancers. Listen as Dr. Aminian explains how the study saw that with significant weight loss, the risk was reversible across race, sex, and age of the patients.
Director of the Center for Immunotherapy and Precision Immuno-Oncology at Cleveland Clinic, Timothy Chan, MD, PhD, joins the Cancer Advances podcast to discuss the Radiation Oncology-Biology Integration Network (ROBIN). Listen as Dr. Chan talks about this new network of centers, the concentration on multi-modality therapies, and the trials that were funded as part of the center.
Jacob Scott, MD, DPhil, radiation oncologist, associate professor, and staff physician-scientist at Cleveland Clinic, joins the Cancer Advances podcast to talk about the research he presented at the American Society of Radiation Oncology (ASTRO) 2022 Annual Meeting. Listen as Dr. Scott discusses preliminary results from a recent Cleveland Clinic study about using GARD to predict overall survival in patients with HPV positive oropharyngeal squamous cell carcinoma treated with radiotherapy.
Stopping hormone therapy treatment to attempt pregnancy may be an option for hormone-receptor-positive breast cancer patients. Halle Moore, MD, Director of Breast Medical Oncology and Co-Director of the Comprehensive Breast Cancer Program joins the Cancer Advances podcast to discuss her research and encouraging findings of the POSITIVE trial that was presented at the San Antonio Breast Cancer Symposium (SABCS) 2022 annual meeting.
The Director of the Blood and Marrow Transplant Program, Craig Sauter, MD, joins the Cancer Advances podcast to discuss optimizing treatments with CAR T-cell and stem cell transplants. Listen as Dr. Sauter talks about his goals to continue expanding the cellular therapy research team and to improve outcomes for transplant patients.
Sharon Sutherland, MD, Director of the Center for Prevention of Cervical Cancer joins the Cancer Advances podcast to talk about the new center created to help prevent cervical cancer. Listen as Dr. Sutherland highlights the goals of the center, and the collaboration with pathology, primary care physicians, and gynecologic oncologists.
Stacey Zahler, DO, a pediatric hematologist-oncologist at Cleveland Clinic Children's, joins the Cancer Advances podcast to talk about the advances in neuroblastoma care for pediatric patients. Listen as Dr. Zahler talks about current treatment options, creating a metaiodobenzylguanidine (MIBG) therapy center at Cleveland Clinic, and studying difluoromethylornithine (DFMO) against cancer cells.
The emotional, psychological, and mental challenges of living with cancer are significant. In this Cancer Advances Podcast, Kaleena Chilcote, MD, Director of Psycho-Oncology at Taussig Cancer Institute talks about mental healthcare in patients who have cancer. Listen as Dr. Chilcote talks about cancer patients' mental health struggles from the beginning of their journey through survivorship and highlights how oncologists can collaborate with psychiatrists to help cancer patients with their quality of life.
Alex A. Adjei, MD, PhD, the new Chair of Cleveland Clinic Taussig Cancer Institute, joins the Cancer Advances podcast to share his vision for Cleveland Clinic Cancer Center. Listen as Dr. Adjei shares his background, goals, and his vision to integrate clinical trials as first line therapy in patient care.
Surgical Director of the Cleveland Clinic Thyroid Center, Joyce Shin, MD, joins the Cancer Advances podcast to provide surgical insights on thyroid cancer. Listen as Dr. Shin discusses the benefits of multidisciplinary care, molecular profiling, and using a fine needle aspiration for thyroid nodules.
R. Matthew Walsh, MD, Department Chair of General Surgery at Cleveland Clinic, joins the Cancer Advances podcast to talk about surgical options for pancreatic cancer. Listen as Dr. Walsh discusses the Whipple procedure, minimally invasive approaches, robotics improvements and pre-habilitation.
Christopher Wee, MD, a medical oncologist from the Genitourinary Medical Oncology Program at Taussig Cancer Institute joins the Cancer Advances podcast to talk about therapies for metastatic prostate cancer. Listen as Dr. Wee discusses Lutetium-PSMA and the clinical trials that showed patients had better response rates and fewer toxicities when they got lutetium on top of their care.
Cleveland Clinic Akron General oncologic surgeon, Anthony Visioni, MD, joins the Cancer Advances podcast to discuss minimally invasive esophagectomies. Listen as Dr. Visioni talks about esophageal cancers and highlights how the team selects the appropriate surgical approach for these patients.
Christopher Weight, MD, Center Director of Urologic Oncology at Cleveland Clinic joins the Cancer Advances podcast to discuss robot assisted retroperitoneal lymph node dissection (RPLND) for the treatment of testicular cancer. Listen as Dr. Weight explains how this robotic surgery allows shorter hospital stays, quicker recovery time, and a lower rate of chylous ascites.
Shilpa Gupta, MD, director of genitourinary medical oncology at Taussig Cancer Institute and co-leader of the genitourinary oncology program at Cleveland Clinic Cancer Center joins the Cancer Advances podcast to discuss her research that was presented at the American Society of Clinical Oncology (ASCO) 2022 annual meeting. Listen as Dr. Gupta gives us insights into the MAIN-CAV trial and platinum-ineligibility in metastatic urothelial cancer.
Medical Director of the Breast Center at Cleveland Clinic Fairview Hospital, Stephanie Valente, DO, joins the Cancer Advances podcast to discuss the Young Women's Clinic. Listen as Dr. Valente discusses the program, survivorship, and the factors physicians address for younger breast cancer patients.
Chirag Shah, MD, co-director of Breast Radiation and Clinical Research in the Department of Radiation Oncology at Cleveland Clinic, joins the Cancer Advances podcast to discuss breast cancer recurrence. Listen as Dr. Shah discusses his research that was presented at the American Society of Clinical Oncology (ASCO) 2022 annual meeting to help patients that are at risk of recurrence.
Director of the Center of Advanced Robotic and Image-Guided Surgery at Cleveland Clinic's Glickman Urological & Kidney Institute, Jihad Kaouk, MD joins the Cancer Advances podcast to discuss single-port transvesical robot assisted radical prostatectomy. Listen as Dr. Kaouk explains advancements that have been made to prostatectomies and how we are continuing to innovate.
Michael Kattan, PhD, Chair of the Department of Quantitative Health Sciences at Cleveland Clinic, and Rahul Tendulkar, MD, radiation oncologist at Cleveland Clinic Cancer Center join the Cancer Advances podcast to discuss nomograms, a calculation tool designed to allow clinicians to evaluate the collective risk of multiple factors at once. Listen as they discuss the creation of nomograms and how they can be helpful to evaluate treatment options for cancer patients.
Seth Rotz, MD, pediatric hematologist-oncologist and Director of the Childhood Cancer Survivorship Program at Cleveland Clinic Children's, joins the Cancer Advances podcast to talk about CAR T-cell therapies and immunotherapy in pediatric patients. Listen as Dr. Rotz explains the long-term survivorship factors to consider when using these therapies and the exciting studies that are being developed for this type of treatment.
Rahul Tendulkar, MD, radiation oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to talk about the PSMA PET scan for patients with prostate cancer. Listen as Dr. Tendulkar explains the benefits and how the scan is changing the way we think about and treat prostate cancer.
Petar Bajic, MD, a urologist in the Center for Men's Health at Cleveland Clinic's Glickman Urological and Kidney Institute, joins the Cancer Advances podcast to discuss Prostate Cancer Survivorship. Listen as Dr. Bajic discusses the difficulties patients face following prostate cancer treatment and the options available to help with urinary and sexual-health issues. He also discusses the importance of a multidisciplinary collaboration between oncologists, general practitioners, and mental health specialists.
J. Joseph Melenhorst, PhD, Director of the Cell Therapy and Immuno-Engineering program and Vice Chair of the Center for Immunotherapy and Precision Immuno-Oncology, joins the Cancer Advances podcast to talk about the future of CAR T-Cell Therapy. Listen as Dr. Melenhorst discusses the progress being made, barriers to overcome, and and how we can improve cellular therapy to treat even more types of cancer.
Nicole Peters, Executive Director of VeloSano in the Cleveland Clinic Philanthropy Institute, joins the Cancer Advances podcast to talk about VeloSano, a year-round fundraising initiative that supports lifesaving cancer research at Cleveland Clinic. Listen as Nicole discusses how VeloSano was started, our flagship Bike to Cure weekend, and highlights of how 100% of the funds go toward advancing cancer research.
Cleveland Clinic hematology oncologist, Allison Winter, MD, joins the Cancer Advances podcast to discuss the early alert process for aggressive lymphoma. Listen as Dr. Winter covers the importance of time to treat for this disease and what Cleveland Clinic is doing to help see patients sooner.
Director of the Lung Cancer Medical Oncology Program at Cleveland Clinic Taussig Cancer Institute, Nathan A. Pennell, MD, PhD joins the Cancer Advances podcast to discuss the KRYSTAL-1 trial, a new treatment option for patients with advanced non-small-cell lung cancer with KRASG12C mutation. Listen as Dr. Pennell explains the trial and findings that were presented at the American Society of Clinical Oncology (ASCO) 2022 annual meeting.
Julie Nowicki PT, DPT, a physical therapist at Cleveland Clinic's Children’s, joins the 100th episode of the Cancer Advances podcast to talk about the Pediatric Hematology/Oncology Mobility Program. Listen as Julie discusses the program and the benefit of physical therapy for children undergoing cancer treatments.
Michael Fritz, MD, Section Head of Facial Plastic and Microvascular Surgery in Cleveland Clinic's Head & Neck Institute, joins the Cancer Advances podcast to discuss anterolateral thigh fascia lata rescue flap for osteoradionecrosis. Listen as Dr. Fritz highlights how the operation allows patients to get back to their everyday lives sooner.
Harry (Adrian) Lesmana, MD, pediatric hematologist/oncologist and medical geneticist at Cleveland Clinic Children's joins the Cancer Advances podcast to talk about pediatric cancer predispositions. Listen as Dr. Lesmana describes gene predispositions for solid tumors vs hematologic cancers as well as the study he is working on to increase the ability to identify these genes through genomic sequencing.
Yogen Saunthararajah, MD, hematologist/oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss his study on repairing cancer cells. Listen as Dr. Saunthararajah discusses how he is trying to change the mindset from search and destroy to replenishment and repair.
Rachel Georgopoulos, MD, pediatric otolaryngologist and Director of the Thyroid Head and Neck Oncology and Pediatric Endocrine (Thyroid HOPE) Center, and Stefanie Thomas, MD, hematologist/oncologist at Cleveland Clinic Children’s join the Cancer Advances podcast to discuss the rise in pediatric thyroid cancer cases. Listen as they discuss the possible factors causing the increase in cases and the multidisciplinary care given at the Thyroid HOPE Center.
Neurologist/Neuro-oncologist in Cleveland Clinic’s Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center, Glen Stevens, DO, PhD, joins the Cancer Advances podcast to talk about the treatment of recurrent glioblastoma. Listen as Dr. Stevens discusses how a study mixing old principles with a new technique may disrupt the BBB, allowing chemotherapy to reach tumor cells.
Byron Lee, MD, PhD, a urologist in Cleveland Clinic's Glickman Urological and Kidney Institute joins the Cancer Advances podcast to discuss expanding surgical options for patients with bladder cancer. Listen as Dr. Lee compares robotic surgery verses open surgery and what we are doing to improve patient outcomes.
Vice Chair of the Department of Hematology and Medical Oncology, and head and neck medical oncologist, Jessica Geiger, MD joins the Cancer Advances podcast to talk about formulating guidelines for salivary gland tumors. Listen as Dr. Geiger explains the six main clinical questions that the guidelines aims to answer.
Peter Rasmussen, MD, cerebral vascular surgeon and Chief Clinical Officer of Virtual Second Opinions by Cleveland Clinic, joins the Cancer Advances podcast to discuss the benefits of Virtual Second Opinions. Listen as Dr. Rasmussen talks about this service at Cleveland Clinic and our goal to give patients the best opinion on what they can do now and in the future.
Lucy Boyce Kennedy, MD, hematology and medical oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast talk about improving outcomes for patients with metastatic melanoma. Listen as Dr. Kennedy explains how treatment for this disease has improved over the last 10+ years.
Faiz Anwer, MD, hematology oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss CAR T-cell therapy for Multiple Myeloma. Listen as Dr. Anwer discusses the trials aiming to move CAR T-cell therapy treatment to the forefront.
Jason Valent, MD, Director of the Multiple Myeloma Program and Co-Director of the Amyloidosis Program at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss the developments of the CAEL-101 trial for patients with AL amyloidosis. Listen as Dr. Valent talks about the discoveries and changes in treatment in each phase of the trial.
Arun Singh, MD, Director of Ophthalmic Oncology at Cleveland Clinic Cole Eye Institute, joins the Cancer Advances podcast to discuss uveal melanoma. Listen as Dr. Singh explains the symptoms to look out for, treatment, and new therapies in development for this rare eye cancer.
Urologic oncologist in the Glickman Urological and Kidney Institute, Zeyad Schwen, MD joins the Cancer Advances podcast to discuss transperineal biopsy and advances in screening for prostate cancer. Listen as Dr. Schwen explains the benefits of the transperineal prostate biopsy technique and why with the use of better imaging, as well as reduced risks of infection, this technique is coming to the forefront.
Suneel Kamath, MD, hematologist/medical oncologist and Siva Raja, MD, PhD, Surgical Director of the Center for Esophageal Diseases joins the Cancer Advances podcast to discuss the Esophageal Cancer Program. Listen as Dr. Kamath and Dr. Raja discuss this multidisciplinary program and the significant advancements that have been made over the last several years including less invasive therapies to treat esophageal cancer.
Aaron Gerds, MD, MS, hematologist in Cleveland Clinic Cancer Center’s Leukemia & Myeloid Disorders Program joins the Cancer Advances podcast to talk about acute myeloid leukemia. Listen as Dr. Gerds discusses less intensive therapies for acute myeloid leukemia and their impact on mortality.
Director of Head and Neck Research and surgical oncologist at Cleveland Clinic, Natalie Silver, MD, MS, joins the Cancer Advances podcast to talk about head and neck cancers and the treatment barriers we are trying to overcome. Listen as Dr. Silver explains how she is trying to bridge the gap between the clinical and translational research with her work on vaccines.
Betty Hamilton, MD, Interim Director of the Blood and Marrow Transplant (BMT) Program at Cleveland Clinic joins the Cancer Advances podcast to discuss research and findings that were presented at the 2021 American Society of Hematology Annual Meeting (ASH). Listen as Dr. Hamilton discusses graft-versus-host disease and the study that evaluates a new regimen.
Rabi Hanna, MD, Chair of the Department of Pediatric Hematology, Oncology and Blood and Marrow Transplantation at Cleveland Clinic Children's joins the Cancer Advances podcast to discuss the use of gene therapy in sickle cell disease. Listen as Dr. Hanna describes how the last several years have brought significant advancements in the field, expanding our understanding and treatment of sickle cell disease, including the possibility of curative gene therapy.
Program Director of Cleveland Clinic Florida's Sarcoma Program, Jorge Manrique-Succar, MD, joins the Cancer Advances podcast to discuss a feasibility study for drug sensitivity testing and genetic profiling in adults with advanced sarcomas. Listen as Dr. Manrique-Succar highlights how the results from the study will lay grounds for future testing and potentially guide future treatment options.
Rabi Hanna, MD, Chair of the Department of Pediatric Hematology, Oncology and Blood and Marrow Transplantation at Cleveland Clinic Children's and Angelika Erwin, MD, PhD, Medical Geneticist at the Center for Personalized Genetic Healthcare at the Cleveland Clinic join the Cancer Advances podcast to discuss the lysosomal storage disease program (LSD). Listen as Dr. Hanna and Dr. Erwin discuss how the interdisciplinary team for children and adults with LSDs is dedicated to improving diagnosis, management and treatment of these disorders.
Nathan Mesko, MD, Center Director, Orthopaedic Oncology, and Co-Director of Sarcoma Care at Cleveland Clinic and Daniel Joyce, MBBCh, surgical oncologist, join the Cancer Advances podcast to discuss the treatment of retroperitoneal sarcomas. Listen as Dr. Mesko and Dr. Joyce highlight the value of having a multidisciplinary team to ensure the best outcomes for patients with retroperitoneal sarcoma.
Brian Hill, MD, PhD, Director of the Lymphoid Malignancies Program joins the Cancer Advances podcast to discuss research and findings that were presented at the 2021 American Society of Hematology Annual Meeting (ASH). Listen as Dr. Hill discusses how CAR T-Cell therapy may be a lifesaving option for patients with relapsed or refractory disease.
Director of the Center for Immunotherapy and Precision Immuno-Oncology at Cleveland Clinic, Timothy Chan, MD, PhD, joins the Cancer Advances podcast to discuss cancer genomic testing capabilities. Listen as Dr. Chan discusses how Cleveland Clinic offers an advanced genomic testing platform as the standard of care to patients with cancer. This expanded capability allows clinicians to identify genetic defects and connect patients with individualized, lifesaving therapies.
Joseph Scharpf, MD, FACS, Director of Head and Neck Endocrine Surgery at the Cleveland Clinic Head and Neck Institute and Katherine Heiden, MD, an endocrine surgeon at the Cleveland Clinic Endocrinology and Metabolism Institute join the Cancer Advances podcast to discuss the latest advances in aggressive thyroid cancer treatment. Listen as Dr. Scharpf and Dr. Heiden discuss how their collaborative approach and new advancements are contributing to the future care of thyroid cancer.
Today, more children are surviving cancer than ever before. But now, increasing efforts are needed to detect and treat late effects as early as possible. Seth Rotz, MD, Director of the Childhood Cancer Survivorship Program at Cleveland Clinic Children’s joins the Cancer Advances podcast to discuss survivorship. Listen as Dr. Rotz highlights how Cleveland Clinic is helping ensure survivor success by identifying and managing late effects in survivors.
Lung nodules are one of the most common incidental findings seen on radiology exams. Director of the Lung Cancer Program and Lung Cancer Screening Program for the Respiratory Institute, Peter Mazzone, MD, MPH, joins the Cancer Advances podcast to discuss Cleveland Clinic's lung nodule management program. The new program was developed to track the management of these lung nodules throughout the enterprise while ensuring care path compliant management in accordance with the most updated guidelines.
Brian Gastman, MD, Surgical and Co-Director of Cleveland Clinic’s Melanoma and High-Risk Skin Cancer Program joins the Cancer Advances podcast to discuss Merkel cell carcinoma (MCC). Listen as Dr. Gastman discusses clinical trials exploring the use of immunotherapy with adoptive cell transfer for advanced melanoma and Merkel cell carcinoma.
Chief of Breast Surgery at Cleveland Clinic Cancer Center, Julie Lang, MD, joins the Cancer Advances podcast to discuss liquid biopsies in breast cancer. Listen as Dr. Lang discusses how liquid biopsies have been used in the past and how she's using them in a new study, funded in part by VeloSano. The study will use next-generation sequencing to detect circulating tumor DNA in the blood samples and to try to improve upon an existing assay based on biomarkers that may be secreted by different types of tumors, benign and malignant.
At Cleveland Clinic, exceptional cancer care is complemented by services that address the emotional, psycho-social, and financial needs of our patients. Melanie Robbins-Ong, DO, palliative and supportive care specialist at Cleveland Clinic Cancer Center joins the Cancer Advances podcast to discuss the importance of patient and family support services. Listen as Dr. Robbins-Ong describes the different types of services we offer not only for our patients but also for their families and care partners.
Jack Khouri, MD, hematologist oncologist at Cleveland Clinic Cancer Center, who specializes in rare plasma cell disorders within the Rare Cancers and Blood Diseases program joins the Cancer Advances podcast to discuss POEMS (i.e., polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes). Listen as Dr. Khouri talks about how the early recognition and diagnosis of POEMS is key to effective management.
Results from a multi-institutional study led by a Cleveland Clinic researcher, DCSionRT®, a biosignature based on multiple biomarkers, may hold the key to solving the treatment of ductal carcinoma in situ (DCIS). Chirag Shah, MD, coinvestigator, and director of Breast Radiation Oncology at Cleveland Clinic joins the Cancer Advances podcast to explain the study and findings that were presented at the American Society for Radiation Oncology annual meeting (ASTRO).
Medical Director of the Breast Center at Cleveland Clinic Fairview Hospital, Stephanie Valente, DO, joins the Cancer Advances podcast to discuss lymphovenous bypass surgery and its connection to breast cancer. Listen as Dr. Valente highlights the procedure and advances being made in breast surgery at Cleveland Clinic.
Suneel Kamath, MD, hematologist and medical oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast for the second time to discuss our new Center for Young-Onset Colorectal Cancer. Listen as Dr. Kamath discusses how the center was established, and how it will allow us to take a comprehensive and multidisciplinary approach to research, diagnosis, and treatment of young-onset colorectal cancer.
Hematologist and medical oncologist at Cleveland Clinic Cancer Center, Suneel Kamath, MD, joins the Cancer Advances podcast to discuss his research on funding disparities. Many cancers with higher mortality rates and high incidence are underfunded, including colorectal, lung, hepatobiliary and uterine cancers. Listen as Dr. Kamath discusses his research from the American Society of Clinical Oncology (ASCO) 2021 annual meeting, highlighting how critical funding is for advancing cancer research.
Paolo Caimi, MD, Associate BMT Director for Cell Therapy at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss new developments and clinical trials in cell therapy. Listen as Dr. Caimi discusses how the field is changing, along with the primary advantages and disadvantages of using cellular therapy compared to chemotherapy.
Pediatric heart failure and transplant cardiologist at Cleveland Clinic Children's, Shahnawaz Amdani, MD, joins the Cancer Advances podcast to discuss cardio-oncology for both pediatric and adult cancer patients who are undergoing chemotherapy or have completed their chemotherapy and are now long-term survivors. Listen as Dr. Amdani highlights when and how cardiac toxicity develops, preventative therapies and how the field has evolved.
Cleveland Clinic recently opened a clinical trial to determine the maximum tolerated dose of a vaccine in patients with non-metastatic triple-negative breast cancer (TNBC). The breast cancer vaccine was invented and developed by Cleveland Clinic immunologist Vincent Tuohy, PhD, and his research team. Cleveland Clinic medical oncologist and principal investigator, G. Thomas Budd, MD, joins the Cancer Advances podcast to discuss the trial origins and what we are looking to accomplish.
Miriam Hernandez, Program Manager in Community Outreach at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to talk about our approach to community outreach and how we’re helping to educate and provide cancer screenings for the underserved population. Listen as Miriam highlights how the community outreach program initially started, what initiatives they are actively doing within the community, and how they are making a difference.
Thomas Gildea, MD, interventional pulmonologist and Section Head of Bronchology in Cleveland Clinic's Respiratory Institute joins the Cancer Advances podcast to discuss the use of pulmonary lung stents for cancer patients. Listen as Dr. Gildea discusses the different ways his team is able to customize lung stents for each patient, including the new FDA-approved 3D-printed stent. Learn how he is continuing to move this field forward and improve our ability to take care of patients before and after the placement of lung stents.
Cleveland Clinic Akron General surgeon, Terence Jackson, MD, joins the Cancer Advances podcast to talk about the latest advances in pancreatic cancer surgery. Listen as Dr. Jackson covers some of the different techniques, which seem to be the most effective, and what types of patients make the best candidates.
Gene Barnett, MD, MBA, neurosurgeon and Director of the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center joins the Cancer Advances podcast to discuss the standard of care for brain metastases. Listen as Dr. Barnett discusses how the traditional surgical approaches for treating patients with brain metastases have evolved and how we are using stereotactic radiosurgery to deliver superior outcomes.
Chair of Physician Leadership and Development within the Mandel Global Leadership and Learning Institute at Cleveland Clinic, Brian Bolwell, MD, joins the Cancer Advances podcast to reflect on his time as leader of Cleveland Clinic Cancer Center and his ongoing journey in leadership. Listen as Dr. Bolwell shares his story on how he became a leader, lessons learned along the way and advice for upcoming leaders in healthcare.
Physicians treating patients with Ewing sarcoma get a chance to discuss challenging cases with experts from Cleveland Clinic, Cleveland Clinic Children's and other leading cancer centers throughout the country in a new National Ewing Sarcoma Tumor Board, led by Matteo Trucco, MD, a pediatric hematologist oncologist at Cleveland Clinic Children’s. Dr. Trucco joins the Cancer Advances podcast to talk about how the tumor board started, what to expect and how you can get involved.
Cleveland Clinic Akron General oncologic surgeon, Anthony Visioni, MD, joins the Cancer Advances podcast to discuss the latest trends in melanoma care. Listen as Dr. Visioni highlights the importance of a multidisciplinary team and how recent clinical trials have caused a paradigm shift in melanoma care.
Christopher Weight, MD, Center Director of Urologic Oncology at Cleveland Clinic joins the Cancer Advances podcast to discuss how high-intensity focused ultrasound (HIFU), a type of focal therapy for treating localized prostate cancer, is emerging as an alternative to more traditional treatments, such as surgery and radiation for select patients. Listen as Dr. Weight explains how improved HIFU technology, coupled with appropriate patient selection, is enabling us to provide this modality as an outpatient procedure.
Betty Hamilton, MD, Associate Director of the Blood and Marrow Transplant (BMT) Program at Cleveland Clinic joins the Cancer Advances podcast to talk about managing chimeric antigen receptor (CAR) T-cell therapy and other novel cellular therapies within different cancer programs to support participation in and expansion of new clinical trials.
Cleveland Clinic is the first hospital in the world to use an FDA-approved ablation technology that can destroy large liver tumors. Director of Cleveland Clinic's Surgical Liver Ablation Program, Eren Berber, MD, joins the Cancer Advances podcast to discuss how the latest technology allows us to treat larger liver tumors more confidently.
Oncoplastic surgery, which combines lumpectomy with reconstructive surgery, is an option for an increasing number of breast cancer patients. Vice-Chairman of the Department of Plastic Surgery at Cleveland Clinic, Risal Djohan, MD, joins the Cancer Advances podcast to discuss the latest techniques in oncoplastic surgery and which patients make ideal candidates.
Director of Strategic Growth for Cleveland Clinic Cancer Center, Shannon Faulhaber, joins the Cancer Advances podcast to talk about the Cancer Affiliate program. Listen as Shannon highlights what it means to be an affiliate of Cleveland Clinic Cancer Center and how your patients and organization can benefit.
Ehsan Balagamwala, MD, radiation oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to talk about stereotactic body radiation therapy (SBRT) for oligometastatic disease. Listen as Dr. Balagmwala highlights how we are pushing the boundaries with SBRT clinical trials, the benefits, and how you can refer a patient.
Onco-nephrology is a nascent field. Nephrologist Roman Shingarev, MD, joins the Cancer Advances podcast to discuss Cleveland Clinic's new onco-nephrology program. Listen as Dr. Shingarev talks about the patients he treats, the program he is building, and what’s ahead in this growing field.
Michael Valente, DO, FACS, FASCRS, Associate Professor of Surgery and Program Director of Cleveland Clinic's Colorectal Surgery Residency Program, joins the Cancer Advances podcast to highlight some of the different strategies for treating peritoneal malignancies, including HIPEC. Listen to learn how treatments have evolved and which patients might be good candidates.
Steven Campbell, MD, PhD, urologic surgeon, and member of the Section of Urologic Oncology in Cleveland Clinic’s Glickman Urological and Kidney Institute, joins the Cancer Advances podcast to discuss the longstanding controversy between partial nephrectomy vs. radical nephrectomy. Listen as Dr. Campbell highlights the possible advantages and disadvantages of each approach and how to know which is best for your patient.
Director of Laparoscopic Liver Surgery, Choon Hyuck David Kwon, MD, PhD, joins the Cancer Advances podcast to discuss some of the recent advances in laparoscopic liver surgery for liver cancer. Listen as Dr. Kwon highlights new approaches and how having a well-established tumor board and multidisciplinary team can yield better results.
Cleveland Clinic Akron General plastic surgeon, Sarah Bishop, MD, joins the Cancer Advances podcast to talk about some of the recent advances in breast cancer reconstruction. Listen as Dr. Bishop covers some of the different reconstructive techniques, which patients are the best candidates and when is the best timing for patients to undergo breast reconstruction.
Michael Fritz, MD, the Director of the Section of Facial Plastic and Microvascular Surgery, joins the Cancer Advances podcast to discuss salvage operations to improve complications or dysfunction related to prior cancer treatment. Listen as Dr. Fritz highlights different techniques used for salvage surgery and how they have evolved over time.
Pediatric Hematologist-Oncologist at Cleveland Clinic Children's, Peter Anderson, MD, joins the Cancer Advances podcast to talk about the challenges and areas of opportunity in pediatric sarcoma care. Listen as Dr. Anderson covers the importance of multidisciplinary care when managing pediatric sarcoma patients and how virtual visits have become more important than ever.
Chair of the Head and Neck Institute at Cleveland Clinic, Patrick Byrne, MD, MBA, joins the Cancer Advances podcast to discuss novel strategies for facial reconstruction after cancer extirpation. He touches on how facial reconstruction techniques have evolved over the past decade resulting in lower complication rates and how the multidisciplinary team works together for better outcomes.
Jaroslaw Maciejewski, MD, PhD, Chair of the Department of Translational Hematology and Oncology Research and Co-Director of the Bone Marrow Failure and Cytopenias Program, joins the Cancer Advances podcast to discuss these rare conditions. Listen as Dr. Maciejewski highlights how the Bone Marrow Failure and Cytopenias program initially started, what patients might benefit and how physicians can make referrals.
Emre Gorgun, MD, colorectal surgeon and co-director of Cleveland Clinics Endoluminal Surgery Center, joins the Cancer Advances podcast to discuss the center and management of lesions in the lower GI tract. Listen as Dr. Gorgun explains our approach to resecting lower GI polyps and how this allows patients to avoid surgery, keep their native organs and have an improved quality of life.
Gastroenterologist, advanced endoscopist, and co-director of Cleveland Clinic's Endoluminal Surgery Center, Amit Bhatt, MD, joins the Cancer Advances podcast to discuss the center and management of lesions in the upper GI tract. Listen as Dr. Bhatt gives insight on why the center was initially created, how it has evolved and its benefits for patients.
Eric Klein, MD, Chairman of Cleveland Clinic’s Glickman Urological & Kidney Institute joins the Cancer Advances podcast to discuss how we are leading the way in prostate cancer care. Listen as Dr. Klein highlights the four areas of innovation that are transforming the treatment of prostate cancer and providing individualized, high-quality care for our patients.
In order to bring novel, more effective therapies to the youngest patients, Cleveland Clinic launched a new, early phase clinical trial program called Cleveland Clinic Children’s Cancer Innovative Therapy Program, led by Matteo Trucco, MD, a pediatric hematologist oncologist at Cleveland Clinic Children’s. Dr. Trucco joins the Cancer Advances podcast to talk about the program and how it's bringing novel therapies to patients with pediatric cancers.
Eric Lamarre, MD, Interim Section Head of Head and Neck Surgery and Oncology with Cleveland Clinic’s Head & Neck Institute, joins the Cancer Advances podcast to talk about HPV-related head and neck cancers. Listen as Dr. Lamarre discusses the shift in demographics for patients with virally related head and neck cancers and the evolution of treatment options.
Sarah Vij, MD, Director of the Center for Male Fertility at Cleveland Clinic, joins the Cancer Advances podcast to discuss Cleveland Clinic's Fertility Preservation Program for Male Cancer Patients. Listen as Dr. Vij discusses the different fertility-sparing techniques used for both pre-pubertal and post-pubertal male cancer patients.
Chair of Subspecialty Care for Women's Health at Cleveland Clinic, Laura Detti, MD, joins the Cancer Advances podcast to discuss Cleveland Clinic's Fertility Preservation Program for Female Cancer Patients. Listen as Dr. Detti highlights the different fertility-sparing techniques used for female cancer patients and the many factors that determine the best option for each patient.
Compared to younger children, cancer rates are higher in adolescents and young adults (AYA). However, AYA's are less likely to receive a prompt diagnosis or be enrolled in clinical trials for innovative treatment. Cleveland Clinic Children's pediatric hematologist oncologist, Stefanie Thomas, MD, joins the Cancer Advances podcast to discuss Cleveland Clinic Children's Adolescent and Young Adult cancer program. Listen as Dr. Thomas covers why the program was developed and how it is impacting our patients.
Graham Schwarz, MD, FACS, Director of the Cleveland Clinic Microsurgery and Breast Reconstruction Fellowship and Co-Director of the Multidisciplinary Center for Lymphedema Care, joins the Cancer Advances podcast to talk about the latest in lymphedema. Listen as Dr. Schwarz discusses the Multidisciplinary Lymphedema Center and how patients can benefit, along with the big impact microsurgery and supermicrosurgery have made in lymphedema treatment.
Emre Gorgun, MD, colorectal surgeon and co-director of Cleveland Clinic's Colorectal Cancer Program, joins the Cancer Advances podcast to discuss our non-operative organ sparing approach for rectal cancer. Listen as Dr. Gorgun explains how this new care path allows about a third of stage II and III locally advanced rectal cancer patients avoid surgery.
Carrie Emch, Program Coordinator for the Cleveland Clinic 4th Angel Mentoring Program, joins the Cancer Advances podcast to discuss the program and how patients and caregivers benefit. Listen as she highlights the programs interactive approach to cancer support, the peer-to-peer matching process, and how you can get involved.
Rabi Hanna, MD, Chair of Pediatric Hematology, Oncology and Blood and Marrow Transplantation at Cleveland Clinic Children's joins the Cancer Advances podcast to discuss best practices for treating pediatric and young adult cancer patients with autism spectrum disorder (ASD). Listen as Dr. Hanna discusses how we treat the patient, not the disease. By making simple adjustments and individualizing therapy can make a significant difference in a patients treatment.
Cleveland Clinic oncologist, Allison Winter, MD, joins the Cancer Advances podcast to discuss Cleveland Clinic's Central Nervous System (CNS) Lymphoma Transplant Program. Listen as Dr. Winter covers how the program started, our multidisciplinary approach to care and which patients with primary CNS lymphoma might benefit most.
Cleveland Clinic Cancer Center Hospice and Palliative Care Specialist, Cory Chevalier, MD, joins the Cancer Advances podcast to discuss palliative care. Listen as Dr. Chevalier discusses our unique model in how we integrate palliative care by using a multidisciplinary approach in both an inpatient and clinical setting.
Robert DeBernardo, MD, Section Head of Gynecologic Oncology at Cleveland Clinic Ob/Gyn & Women’s Health Institute joins the Cancer Advances podcast to discuss hyperthermic intra-peritoneal chemotherapy (HIPEC), specifically in gynecologic cancers. Listen as Dr. DeBernardo discusses the procedure and use of HIPEC along with the type of patient and cancers that are ideal for HIPEC treatment.
Samuel Chao, MD, radiation oncologist in the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center of Cleveland Clinic Neurological Institute and Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to talk about the work he recently presented at the American Society of Radiation Oncology (ASTRO) 2020 Annual Meeting. Listen as Dr. Chao discusses preliminary results from a recent Cleveland Clinic study that demonstrate that 18F-fluciclovine PET/CT has the potential to distinguish radiation necrosis from tumor progression in brain tumors previously treated with stereotactic radiosurgery (SRS).
Cleveland Clinic Center Director for Musculoskeletal Oncology, Nathan Mesko, MD, joins the Cancer Advances podcast to discuss how Cleveland Clinic is managing sarcoma and cancers involving the bone and soft tissue. Listen as Dr. Mesko covers time to treat in sarcoma patients, the breadth of specialties involved in our multidisciplinary approach to care and how we are collaborating with other Institutions through our national tumor registry.
Eric Klein, MD, Chairman of Cleveland Clinic’s Glickman Urological & Kidney Institute joins the Cancer Advances podcast to discuss the IsoPSA Test, now being offered at Cleveland Clinic. The IsoPSA test is a novel prostate-specific antigen assay for patients with a PSA > 4ng/ml who are facing a decision on prostate biopsy. Listen as Dr. Klein discusses how the IsoPSA test differs from conventional PSA testing and how your patients can benefit.
Sudipto Mukherjee, MD, MPH, Director of Rare Cancers and Blood Diseases at Cleveland Clinic, joins the Cancer Advances podcast to discuss our approach to rare cancers. Patients with rare cancers and blood diseases often have difficulty finding clinicians with necessary expertise. Listen as Dr. Mukherjee discusses how Cleveland Clinic Cancer Center's Rare Cancers and Blood Diseases initiative uses a multidisciplinary approach that includes a highly sub-specialized team of medical and radiation oncologists, surgeons, radiologists and pathologists.
Just like traits such as eye color or height, an increased risk to form certain types of cancers can also be genetic. Approximately 5% of all colorectal cancer cases are hereditary, and Dr. David Liska, Director of Cleveland Clinic's Sanford R. Weiss, MD Center for Hereditary Colorectal Neoplasia, joins Cancer Advances to discuss these cancers and how the multidisciplinary team at The Weiss Center is dedicated to preventing, treating, and educating patients and their families.
Alok Khorana, MD, Director of The Gastrointestinal Malignancies Program and Vice Chair for Career Academic Development at Cleveland Clinic, joins the Cancer Advances podcast to discuss some of his key takeaways from ASCO 2020, along with the important role clinical trials play in cancer advancements, especially GI cancers.
Newer therapies are not only allowing us to care for our cancer patients better, but oftentimes, it helps increase lifespans with fewer toxicities. Laurie Matt-Amaral, MD, MPH, who specializes in Hematology Oncology at Cleveland Clinic Akron General’s McDowell Cancer Center, joins the Cancer Advances podcast to discuss target therapies for lung cancer. Listen as Dr. Matt-Amaral shares her insights into novel strategies that are evolving with genetic driver mutations and how immunotherapy is changing the way we treat metastatic disease patients.
Cleveland Clinic Cancer Center regional medical oncologist, Kasra Karamlou, MD, joins the Cancer Advances podcast to discuss the management of myeloma and how regional facilities collaborate with main campus to bring the same high level care to their patients locally.
Brian Gastman, MD, Plastic Surgeon and Medical and Surgical Director of the Melanoma and High-risk Skin Cancer Program at Cleveland Clinic, joins Cancer Advances to discuss the latest in Merkel Cell Carcinoma. He touches on treatment options, research and results, along with what we can expect to see in the coming years.
Conor Delaney, MD, PhD, President and CEO of the Cleveland Clinic Florida region, joins the Cancer Advances podcast to discuss minimally invasive surgery (MIS). Listen as Dr. Delaney shares his insight on which patients and types of cancer benefit most from MIS, the importance of a multidisciplinary team and what referring physicians should look for when considering who should do their patient's surgery.
Single-fraction SBRT is safe and effective in treating early stage, medically inoperable NSCLC, according to a ten-year retrospective study of 229 patients, the largest single-institution report to date. Gregory Videtic, MD, radiation oncologist at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss the findings that were presented at the American Society for Radiation Oncology (ASTRO) annual meeting.
Cleveland Clinic hematologist/oncologist, Bhumika Patel, MD, joins the Cancer Advances podcast to discuss Cleveland Clinic Cancer Center's new CHIP Clinic. The CHIP Clinic screens and monitors patients with clonal hematopoiesis of indeterminate potential (CHIP): somatic mutations in blood or bone marrow cells that increase the risk of blood cancers and heart disease. Listen as Dr. Patel shares how she believes the CHIP Clinic will implicate how we treat patients moving forward, including cancer survivors.
Jame Abraham, MD, Chair of the Department of Hematology and Medical Oncology at the Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss the latest in breast cancer clinical trials. Listen as Dr. Abraham shares his insight on how to get the word out to patients about clinical trials, the role COVID-19 has played in trial logistics, along with which trials he thinks are likely to have the biggest impact in how we treat patients with breast cancer.
John Suh, MD, Chair of the Department of Radiation Oncology at Cleveland Clinic Cancer Center, joins the Cancer Advances podcast to discuss leadership development. Dr. Suh shares his personal journey on becoming a leader. He highlights the important role coaching and mentorship, self-reflection and emotional intelligence has in continuous improvement.
Chirag Shah, MD, Director of Breast Radiation and Clinical Research in the Department of Radiation Oncology at Cleveland Clinic, joins the Cancer Advances podcast to discuss the latest in breast cancer radiation. Dr. Shah shares how radiation for the breast has evolved over the past decade, giving breast cancer patients multiple options for radiation treatment. Listen as Dr. Shah discusses how we use a multidisciplinary approach when establishing which type of radiation is best suited for our patients.
Genetic testing and screening in gynecologic cancer patients has evolved over the last several years. Miriam AlHilli, MD joins the Cancer Advances podcast to discuss the latest in genetic testing, screening and prevention.
Colorectal cancer is typically the second or third leading cause of cancer-related death in the United States. Scott Steele, MD, Chair of Colorectal Surgery at Cleveland Clinic joins the podcast to discuss updated screening guidelines and recommended methods, as well as the alarming increase in early-onset colorectal cancer.
Upon completing cancer treatment, a patient’s journey is truly just beginning. Halle Moore, MD, Director of Breast Medical Oncology and Co-Director of the Comprehensive Breast Cancer Program discusses Cleveland Clinic’s breast cancer survivorship program. Listen as Dr. Moore shares her learnings from more than a decade of research to improve the quality of life for cancer survivors.
Cleveland Clinic Cancer Center oncologist Shilpa Gupta, MD discusses promising findings in the treatment of advanced bladder cancer in this week's Cancer Advances podcast. Dr. Gupta shares data from the phase II Bladder Cancer Signal Seeking Trial (BLASST-1), recently presented at the American Society of Clinical Oncology’s Genitourinary Cancers Symposium. She also provides an update on additional in-progress clinical trials and what’s on the horizon for bladder cancer research.
With the onset of the global pandemic in early 2020, we were fast tracked into the world of virtual visits in order to continue seeing cancer patients who were hesitant or unable to seek in-person care. James Stevenson, MD, Vice-Chair of the Department of Hematology and Medical Oncology in the Taussig Cancer Institute discusses how virtual visits are transforming the way we deliver cancer care for patients. He touches on the benefits for both patients and providers, the best platforms to use, and what’s on the horizon as we continue to utilize this ever-evolving technology.
Invasive lobular breast cancer accounts for approximately 10-15% of all invasive breast cancer cases and is the second most commonly diagnosed type of invasive breast cancer. Megan Kruse, MD joins the podcast to discuss ongoing and upcoming research to identify optimal treatment plans and outcomes for patients fighting this disease.
Timothy Chan, MD, Director of our new Center for Immunotherapy and Precision Immuno-Oncology, joins us to discuss his vision to help advance immunotherapy, developmental therapeutics and research at Cleveland Clinic both in Northeast Ohio as well as at our regional sites in Florida, Abu Dhabi and eventually London. Dr. Chan discusses his vision on collaborating and breaking down silos not only internally at Cleveland Clinic for the benefit of patients but more widely across NCI cancer centers and with industry.
Matt Kalaycio, MD, Vice-Chair of the Taussig Cancer Institute joins us to discuss how we’ve adjusted the way we deliver care to cancer patients during a global pandemic. He touches on how we’re protecting our patients and caregivers, how we quickly adapted our cancer center to promote social distancing, appropriate use of PPE and proper screening, the increase use of virtual visits and the importance of patients to not delay screenings and continue to seek care in a safe way.
A prototype blood-based screening test evaluated by Cleveland Clinic researchers and other experts can accurately identify the presence and originating site of 12 high-mortality cancer types, across all stages of progression, with a low false-positive rate, according to the latest results of an ongoing national clinical trial. Eric Klein, MD, Chairman of Cleveland Clinic’s Glickman Urological & Kidney Institute and the co-principal investigator of Cleveland Clinic’s portion of the study joins the Cancer Advances podcast to discuss this trial and the path forward to further validate this multi-cancer detection approach.
Imagine yourself in your patients’ shoes, feeling the anxiety and fear of having just been diagnosed with cancer. Now imagine being told it’s going to take 6 weeks or longer before you’re able to receive treatment. Brian J. Bowell, MD, Chairman of Cleveland Clinic Taussig Cancer Institute, discusses how reducing time to treatment became a vision for him and how he helped inspire our cancer center teams to share best practices and reduce time to treat over the past several years. He discusses barriers we still need to tackle and provides recommendations on how other cancer centers can help make progress on this critical issue.